The Rpm-1/Phr Signaling Hub Modulates Tau-Induced Neurodegeneration Through Regulation Of Microtubule Stability And Mapk Pathways In C. Elegans, Xinxing Ding

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia, are characterized by the accumulation of pathological tau proteins and progressive neuronal loss. Although research regarding tau-mediated toxicity is extensive, the specific pathology that determine whether neurons maintain homeostasis or succumb to collapse under tau-induced stress remain incompletely elucidated. A central, yet still insufficiently understood, feature of these diseases is the disruption of the microtubule (MT) cytoskeleton . The PHR protein family is evolutionarily highly conserved; within this family, RPM-1 in C. elegans functions as an intracellular signaling hub that regulates axon development, synapse formation, axon termination, and various microtubule-associated processes. This …

Color-Coding: An Aid Or Hindrance In A Multi-Unmanned Aerial Vehicle Supervisory Control Task, Austin Daniel Wood

Theses and Dissertations

The purpose of the current study was to investigate the effect of coding types (i.e., alphanumeric coding, color-coding, and redundant color + alphanumeric coding) for vehicle identification and status information on pilots’ recognition performance, situational awareness (SA), and workload for a multi-vehicle operations ground control station (GCS) supervisory control task. With the aviation industry's push towards operators supervising and controlling multiple vehicles, it is pertinent to identify design features that support the capabilities and limitations of human operators. The current study employed a within-subjects, repeated-measures experimental design, in which a sample of 33 students with aviation experience performed three trials, …

Use Of Active Learning In The Teaching Of The Veterinary Science Course, Cary Rita

All Dissertations

Agricultural education is rooted in active learning, where students develop skills and learning opportunities through hands-on experiences on classroom farms, greenhouses, and even school-based grooming salons. Recent policy and funding revisions have shifted the measures of success in agricultural education programs towards the number of students earning industry-based certifications. This shift has led to the adoption of a test-focused curriculum, often provided by the company offering the certification exam. While the certification-aligned curriculum provides strong content for veterinary knowledge, the problem is that it is often at the expense of hands-on learning. Balancing active learning while also preparing the students …

Novice Teachers' Effective Use Of Progress Monitoring To Improve Student Outcomes, Melanie Williams

All Dissertations

Novice teachers, those with five years or less of classroom experience, are often burdened with keeping up with constant reform and challenges, while under constant pressure to improve student outcomes. This dissertation in practice aimed to address this burden by reducing the number of students receiving Tier 3 intervention, the highest level of intervention before a special education referral.

Grounded in the theory of improvement, the intervention provided teachers with one day a month of professional development and dedicated time to focus on collaboration of Tier 2 progress monitoring data analysis. Tier 2 interventions focus on reteaching and extending state …

Who Gets To Belong: Using A Tier Two Intervention To Increase Student Sense Of Belonging And Supportive Student-Teacher Relationships, Kevin L. Smith

All Dissertations

Students do better in school when they feel like they belong and have positive relationships with their teachers. This study examined whether dialogue circles as a Tier 2 intervention could help students feel more connected to their teachers and school. The study took place in a small, rural, Title I middle school. Although the intervention did not lead to clear improvements in grades, attendance, or discipline, it did achieve its aim of having at least 80% of pre and post survey respondents report having at least one adult who helped them feel a sense of belonging at school. Furthermore, students …

Unlocking Potential: How High-Fidelity Plcs Protect First Graders From Over-Identification In Tiered Placement, Tomeka D. Love

All Dissertations

Nationally, the demand for special education services under the Individuals with Disabilities Education Act (IDEA) has reached an unprecedented peak, serving 7.5 million students (representing 15% of all public school students) in the 2022–23 school year. While national academic discussions regarding socioeconomic hurdles and systemic inequities frequently center on urban environments, minoritized students in rural communities face a persistent and disproportionate over-representation in special education. This trend is driven by complex intersections of geographic isolation, systemic resource allocation issues, and cultural misalignments in assessment practices.

At the local level, Love and Logic Elementary School [pseudonym], a rural K-5 institution, faces …

Changing The Trajectory: A School-Based Mentoring Intervention To Improve Attendance And Belonging, Alexis Black

All Dissertations

Chronic absenteeism continues to impact student academic outcomes, school engagement, and long-term success, particularly at the high school level. Research has shown that students who experience consistent absenteeism are more likely to report lower levels of school connectedness and belonging. This improvement science dissertation examined whether a school-based mentoring intervention could improve attendance and students’ sense of belonging among ninth-grade students identified as chronically absent at a public high school in South Carolina.

The intervention, titled the On Track Together Mentoring Program, paired school staff mentors with students for weekly mentoring sessions over a 10-week implementation period. The program focused …

Lesson Plans, Teacher Self-Efficacy, And Ml Achievement: A Quantitative Study Of Teachers Incorporating Language Acquisition Within Lesson Plans To Improve Multi-Lingual Learner Achievement, Patrick R. Withers

All Dissertations

South Carolina’s public schools are increasingly facing the challenge of addressing the needs of a growing number of multi-lingual (ML) learners. ML learners are increasingly marginalized in society and schools, and show lower rates of achievement within schools. Schools are faced with providing effective tier 1, universal instruction for all students, including ML learners. This quantitative study seeks to improve ML achievement through incorporation of language acquisition skills within the classroom lesson plans. It is also the goal of this study to measure teacher self-efficacy of the selected study cohort.

This study takes place in a large suburban high school …

Closing The Gap: Addressing College Readiness Inequities Through Dual Enrollment Policy And Practice Reform, Tabytha L. Walls

All Dissertations

This dissertation employed improvement science to increase college readiness at Phosphate Grove High School by expanding the dual-enrollment program. At this research site, a majority-minority, Title I high school in South Carolina, dual enrollment serves as the primary pathway towards college readiness on the state report card. College readiness at this school has been low for many years, and participation in the program has not been representative of the school's size. Many students meet the academic eligibility requirements, but students and families are unaware of the opportunities and have difficulty navigating the sign-up process.

This study aimed to address some …

From Referral To Results: Strengthening Mtss Pre-Referral Practices To Improve Special Education Referral Decision-Making, Capricia K. White

All Dissertations

The steady rise in special education identification rates continues to outpace overall U.S. public school enrollment trends, raising important questions about how students are identified, labeled, and referred for services. Despite South Carolina's MTSS mandate under Act 213, implementation remains inconsistent across schools. As a result, referral decisions may be based on limited evidence of student response to targeted general education supports.

The purpose of this Dissertation in Practice was to examine how a school-based improvement initiative, Project FOCUS (Fidelity, Outcomes, Collaboration, and Unified Support), strengthened MTSS pre-referral practices to support special education referral decision-making. Guided by Improvement Science, the …

Making The Case For Historically Minoritized Students At Career Centers With A Focus On Agriculture, Janine Honey Sutter

All Dissertations

Historically minoritized students are still underrepresented in many Career and Technical Education (CTE) programs, such as agricultural education, even though these programs offer valuable academic, workforce, and postsecondary opportunities. This dissertation used Improvement Science to explore whether educator perceptions and communication practices played a role in this underrepresentation at Liberty Career Center. It also examined whether targeted informational interventions could help educators become more aware of and more positive about Career Center opportunities.

Following Improvement Science principles, the study used a continuous improvement approach to find system-level barriers and test new ways to improve communication between the Career Center and …

Growing Our Own Garden: The Implementation Of Cross Curricular And Cross Grade Level Teacher Rounds To Increase Professional Learning Individualization And Feedback, Logan Greene

All Dissertations

Educators are constantly faced with balancing the demands of teaching and professional learning expectations from their districts. Concurrently, administrators are routinely prevented from providing adequate feedback for classroom instructional practices with observations instead focused upon generic and formulaic checks for classroom activities. This results in a gap of intentional professional learning and growth for educators.

The idea of instructional rounds sought to provide teacher-to-teacher feedback for educators to grow their practice together. The original theory focused on groups of teachers operating under a school or district goal of improvement. Instructional rounds have shown positive effects for teacher happiness and student …

Teacher Self-Efficacy And Student Engagement In Rural Science, Technology, Engineering, And Mathematics Magnet Schools: A Correlational Study Within An Improvement Science Context, Deirdre L. Appleby

All Dissertations

Teacher self-efficacy in magnet-themed integration represents a critical, district-influenceable condition shaping instructional experiences in rural Science, Technology, Engineering, and Mathematics (STEM) magnet programs. Persistent under-enrollment of Black, Latinx, and economically disadvantaged students in these settings highlights ongoing inequities in access and participation that may be influenced by upstream instructional conditions. Grounded in Bandura’s Social Cognitive Theory and situated within an improvement science framework, this study examines teacher self-efficacy as a key system-level factor associated with student engagement.

This study employs a correlational research design within an improvement science context to examine the relationship between changes in teacher self-efficacy and changes …

Technology Enhanced Math Instruction And Student Achievement, Barbara Warren

All Dissertations

ABSTRACT

This study examines how one teacher in a large rural high school in South Carolina integrates an AI technological intervention as a supplemental tool, specifically as part of blended learning, to help increase math achievement for students in Geometry with Statistics.  Evidence-based interventions, such as technology enhanced math instruction, encompass a diverse range of tools used by teachers, including an AI-driven high-dose tutorial which is a tool that educators use to diagnose, teach, and assess targeted skills.  The key to the success of the AI tutorial is that it is programmed to use evidence-based practices (Fesler et al., 2026) …

A Mixed-Methods Study Of The Lived Experiences Of Patients And Caregivers Receiving Home Health Occupational Therapy Services, Peyton A. Mendias

Student Capstone Papers

Home health occupational therapy (OT) supports individuals’ safety, independence, and participation in their natural environments; however, patients and caregivers may face barriers that affect the implementation of therapy recommendations. This capstone project explored patient and caregiver experiences with home health OT and identified factors influencing implementation of OT recommendations. We used a sequential explanatory mixed-methods design guided by the Capability, Opportunity, Motivation–Behavior (COM-B) model. Eight participants, including three patients and five caregivers, completed an electronic survey, and one caregiver participated in a follow-up semi-structured interview. We analyzed quantitative data using descriptive statistics and qualitative data using reflexive thematic analysis. Findings …

Exploring The Effect Of Writing-To-Learn Practices On Critical Thinking In A Graduate Teacher Education Program, Alisa Alybaeva

GHEA21 Publications

This project investigates the impact of writing-to-learn practices on the critical thinking skills of first-year students in a graduate teacher preparation program in the Kyrgyz Republic. For this purpose, multiple writing-to-learn strategies (such as Focused Freewriting, Loop Writing, Private Freewriting, Writing in the Zones, Dialectical Notebooks, and others) were integrated into the academic writing course instruction. The analysis of student responses at the beginning and end of the course demonstrated a movement from general statements towards richer responses with evidence of perspective taking, metacognitive reflection, and synthesis. Additionally, student reflections revealed that writing-to-learn practices provided space to overcome writing anxiety, …

Reading The Western Canon From Elsewhere: Teaching Political Theory Through Writing, Zlata Božac

GHEA21 Publications

No abstract provided.

Barriers To Access: Examining Nonprofit Service Delivery In Rural Communities, Elizabeth Knight

School of Professional and Continuing Studies Nonprofit Studies Capstone Projects

Around sixty-six million Americans live in rural communities; however, the research on what accessibility barriers exist for rural residents accessing nonprofit services is limited. Rural communities often face persistent barriers to accessing essential services, including transportation challenges, geographic isolation, and financial hardship. Nonprofit organizations employ strategies to respond to these barriers; however, organizational capacity constraints make it difficult for nonprofits to alter their service delivery strategies. This study uses semi-structured interviews with nonprofit leaders to identify what nonprofit accessibility barriers can currently be seen in rural Virginian communities. Findings also explore how nonprofits navigate these barriers and what they do …

Improving Obesity Management In Primary Care Through Provider Education, Natalie Anderson

Doctor of Nursing Practice Projects

Background: Childhood obesity is a significant public health concern associated with metabolic, cardiovascular, and psychosocial complications. Despite the availability of evidence-based pediatric obesity management guidelines, adherence to these guidelines remains inconsistent in primary care settings. Purpose: This evidence-based quality improvement project aimed to determine whether provider education on the 2023 American Academy of Pediatrics (AAP) Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity, combined with implementation of an electronic health record (EHR) clinical decision support prompt, improved provider knowledge and adherence to guideline-recommended obesity management practices. Method: A pre-post quasi-experimental study was …

Aegic Blogposts - Climate Impacts On Grain Production, Ross Kingwell, Nicholas Thorsager, David Stephens, Ian Foster, Imma Farre

Grain and other field crops published reports

The Australian Export Grains Innovation Centre (AEGIC) was an independent, not-for-profit organisation established in 2012 by the Western Australian Government and the Grains Research and Development Corporation (GRDC). Its core mission was to increase the value and international competitiveness of Australia’s multibillion-dollar export grains industry. AEGIC ceased operation at the end of 2025.

Early in its history between 20 to 30 staff from the former Western Australian Department of Agriculture were seconded to AEGIC. Following the formation of DPIRD, AEGIC continued to receive substantial annual funding support from DPIRD.

This publication is a legacy document containing collated AEGIC blog posts …

Power Signature-Based Hardware Security Techniques For The Internet Of Things, Ashish Mahanta

Dissertations

The rapid proliferation of the Internet of Things (IoT) has introduced significant security challenges, particularly concerning stealthy, instruction-level malicious code injections that evade traditional software defenses. While conventional power analysis techniques are highly effective at detecting such subtle abnormalities, they require capturing high-resolution, voluminous power trace data. This dependency necessitates bulky data acquisition (DAQ) instrumentation, power-hungry analog-to-digital converters (ADCs), and intensive computational resources, making these methods impractical for deployment on resource-constrained IoT devices. To bridge this critical gap, this dissertation presents a novel hardware security paradigm, the Power Rising and Descending Signature (PRIDES) methodology. Instead of quantizing actual power consumption …

Transcriptional Regulation In The Uterine Luminal Epithelium, Evelyn A. Carrion

Dissertations and Theses (Open Access)

Transcriptional Regulation in the Uterine Luminal Epithelium

Evelyn A. Carrion

Advisor: Richard R. Behringer, PhD

Abstract

The uterus is an organ comprised of multiple tissues that are essential for women’s health and reproduction. The uterus is composed of multiple tissue layers, including the perimetrium, myometrium, and the endometrium. The endometrium is the inner lining of the uterus, and contains the luminal epithelium, glandular epithelium, and stroma. The luminal epithelium is a simple columnar layer of cells that is necessary for embryo implantation. The uterus is derived in part from the embryonic precursor tissue called the Müllerian duct. There are no …

Regulation Of Müllerian Duct Mesenchyme Transcription During Mammalian Sex Differentiation, Haowen Li, Richard R Behringer, Rachel D Mullen

Dissertations and Theses (Open Access)

Sp7/Osterix (Osx) encodes a zinc-finger transcription factor of the Specificity-protein family discovered by Nakashima et al. at the MD Anderson Cancer Center. While primarily recognized for its role in osteogenesis, Osx has also been implicated in mammalian reproductive development, particularly in male sex differentiation, where Müllerian Duct (MD) regression occurs, mediated by anti-Müllerian hormone (AMH) signaling. AMH-induced regression signals are transduced by the mesenchymal tissue surrounding the ductal structure, known as the Müllerian Duct mesenchyme (MDM). It was discovered that AMH signaling is necessary and sufficient for driving Osx expression in MDM. A previous transgenic mouse reporter …

Exploring The Impacts Of Research Including Zealous Genz-Ers (Rizz), Afraah Hawa, Andrea Bradley-Ewing Mpa, Ma, Kimberly A. Randell, Md, Msc, Yesenia Montoya, Karynn E. Glover

Posters

No abstract provided.

My God Is My Mercy: A Philological And Exegetical Study Of The Use Of Hesed In The Old Testament And Its Echoes In The New Testament, Sister Mary Agatha Hester, O.P.

Theology Graduate Theses

One little word can have a mighty impact. This is the case with the Hebrew word hesed.  Having encountered hesed in Scripture scholarship, pursuit of its nature and nuance has become a quest that has resulted in this thesis. What follows is a philological and exegetical study of the meaning and use of hesed in the Old Testament, its intertextual echoes in the New Testament, and its implications for right living. First, the use of hesed is analyzed in the context of the Old Testament, focusing on Exodus 34:6-7, which serves as the exemplar text. Using the work of …

Visual Cues Attract Adult Tunga Penetrans (Siphonaptera: Tungidae), Ayako Hyuga, Paul Ouma, Lynne Elson, Kazuchiyo Miyamichi, Satoshi Kaneko, Kensuke Goto, Tullu Bukhari, Jürgen Krücken, Ulrike Fillinger

All Peer-Reviewed Publications

Tunga penetrans (Linnaeus, 1758) (Siphonaptera: Tungidae) is an ectoparasitic flea whose adult females cause tungiasis by embedding into the host’s skin. Environmental, social and financial challenges in tungiasis endemic areas have left this disease neglected and lacking locally available control measures. One possible approach for controlling T. penetrans targets its off-host stages; however, surveillance tools for adult fleas are still lacking. Moreover, host-seeking cues and behaviour of adult T. penetrans remain largely unknown. In this study, we show that visual cues are attractive to adult T. penetrans. Newly emerged T.penetrans responded to light stimuli across a broad spectrum, ranging from …

Advancing Health Equity In Global Oncology: A Collaborative Academic-Cancer Society-Industry Program To Address Health Disparities In Sub-Saharan Africa, Kenneth Merrell, Ben Kamdem-Talom, Hannah Anie, Christine Wekesa, Nomsa Tsikai, Miriam Mutebi, Rakiya Saidu, Nwamaka Lasebikan, Adamu Bojude, Randiak Alaro

General Surgery, East Africa

Purpose Cancer care capacity in sub-Saharan Africa (SSA) is constrained by late diagnosis and limited treatment access. Few funding mechanisms support innovative, locally led programs to address these challenges. A collaborative initiative was developed to strengthen oncology care through quality improvement (QI) projects.

Materials and Methods The program was developed by Global Bridges Oncology (GBO) at Mayo Clinic, Pfizer Global Medical Grants, and the African Organisation for Research and Training in Cancer. A committee composed primarily of African oncology experts guided the process. An RFP was disseminated across SSA in English, French, and Portuguese, inviting applications to improve diagnostic and …

Enhanced Communication Is Fundamental In Providing Quality Care, Jacqueline Turcotte Rn, Msn, Ccrn

MaineHealth Maine Medical Center

No abstract provided.

Effects Of Peer-Mediated Constant Time Delay Instruction On Science Vocabulary Acquisition For Students With Moderate Intellectual Disabilities, Amy S. Roberts

Electronic Theses and Dissertations

This study examined the effectiveness of combining peer-mediated embedded instruction with constant time-delay (CTD) procedures to improve Agriscience vocabulary learning among secondary students with moderate intellectual disability who were educated in an inclusive Agriscience classroom. A multiple-probe across participants design was conducted with three students with moderate intellectual disability. Trained peer tutors provided embedded vocabulary instruction during naturally occurring classroom activities. Results showed an increase in independent correct responding for all participants following the implementation of the intervention. Procedural fidelity, interobserver agreement, Tau-U effect size, and social validity data further demonstrated that the intervention was implemented consistently and was viewed …

Building Careers In The Age Of Ai, Laura Bulkeley

Paul English Applied Artificial Intelligence (AI) Institute Publications

This presentation explores how career advisors can support students navigating a rapidly changing job market shaped by artificial intelligence. It examines how students can reframe traditional career paths around transferable skills, adaptability, human connection, and continuous learning while considering what employers increasingly value in candidates. The presentation discusses the importance of developing high-agency professionals who can learn new technologies, communicate and collaborate effectively, and apply human reasoning alongside AI. It also provides a practical application of generative AI in the job search process, including customizing resumes, preparing for interviews, and receiving feedback on writing while maintaining ownership of one's experiences, …