Digital Commons Network^™

2025-10-28 Executive Council Minutes, Laura Bagley

Executive Council Minutes

No abstract provided.

Research And Innovation Update, October 29, 2025, Office Of The Vice President For Research And Innovation

Office of Research, Economic Engagement and Outreach

No abstract provided.

2025-10-29 Mariners Fall Short Of World Series, Julia Pilch

The Spectator Online

No abstract provided.

2025-10-29 Canvas Outage Exposes Digital Dependency, Samantha Custodi

The Spectator Online

No abstract provided.

2025-10-29 Fledgling First-Gen Center Promotes Student Success, Lily Collins

The Spectator Online

No abstract provided.

2025-10-29 A Haunting Fable On The Amazon River, Cornish Playhouse Presents ‘The River Bride’, Keagen Brooks-Torres

The Spectator Online

No abstract provided.

Spectrum, Volume 55, Issue 7, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: New Scholarship to Support Engineering Students -- The Look of Sustainability -- Springing into Registration -- Effect of Social Media on Mental Health -- Say Yes to the Dress: SHU Students at NYCBFW -- Bovardi Breaks Record as Playoffs Near

Soovin Kim, Violin

Bailey School of Music Concert Programs

Korean-American violinist Soovin Kim is an exciting player who has built on the early successes of his prize-winning years to emerge as a mature and communicative artist. After winning first prize at the Niccolò Paganini International Competition, Mr. Kim was recipient of the prestigious Borletti-Buitoni Trust Award, an Avery Fisher Career Grant, and the Henryk Szeryng Foundation Career Award. Today he enjoys a broad musical career, regularly performing repertoire such as Bach sonatas and Paganini caprices for solo violin, sonatas for violin and piano by Beethoven, Brahms, and Ives, string quartets, Mozart and Haydn concertos and symphonies as a conductor, …

Chromatin Profiling Identifies Putative Dual Roles For H3k27me3 In Regulating Cell Type-Specific Genes And Transposable Elements In Choanoflagellates, James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, Alex De Mendoza, David S Booth

2020-Current year OA Pubs

Chromatin-based mechanisms contribute to the exquisite regulation of gene expression during animal development. But how those mechanisms evolved remains elusive. Here we investigate chromatin regulatory features in the closest relatives of animals, choanoflagellates. In a model choanoflagellate Salpingoeca rosetta, we compare chromatin accessibility and histone modifications to gene expression. Accessible genomic regions in S. rosetta primarily correspond to gene promoters, and we find no evidence of distal gene regulatory elements that resemble enhancers deployed to regulate developmental genes in animals. Remarkably, the histone modification H3K27me3 decorates genes with cell type-specific expression, revealing a functional similarity in S. rosetta and animals. …

Does Cognitive Frame Affect Clinical Reasoning Among Medical Students? A Cross-Sectional Study, Xiao C. Zhang, Sara A. Belko, Andrew J Monick

Department of Emergency Medicine Faculty Papers

Background Diagnostic errors affect patient safety and lead to high costs. Cognitive bias is a key source of diagnostic error, and the framing effect poses a particular clinical challenge. The extent to which individual factors affect susceptibility to the framing bias is unclear, and the role of expertise in particular is contested across the literature. Objectives This study investigated the effects of framing bias on diagnostic reasoning among medical students. We hypothesised that the effects attributable to framing would be mediated by the number of years of medical education completed. Methods Participants were randomly assigned on an automated basis with …

Bankruptcy Judging After Williamson, Vincent S.J. Buccola

Coase-Sandor Institute for Law & Economics Research Paper Series

This Essay asks how bankruptcy judges ought to orient their substantial, statutory discretion in business reorganization cases. The motivating observation is that bankruptcy law enacts a kind of forced integration of productive assets. To shed light on the contemporary problems that bankruptcy judges face, I thus look to two classic approaches to the economic theory of the firm—from Oliver Williamson and from Oliver Hart. I conclude that nonjudicial institutions have largely surmounted the problems to which their theories point, leaving a different, and probably narrower, set of issues to worry about. Bankruptcy judges who have a notion that their job …

Translational Framework Linking Perfluoroheptanoic Acid (Pfhpa) Exposure To Metabolic Dysfunction Associated Steatotic Liver Disease In Adolescents, Brittney O Baumert, Ana C Maretti-Mira, Douglas I Walker, Zhenjiang Li, Nikos Stratakis, Hongxu Wang, Yinqi Zhao, Fabian Christoph Fischer, Qiran Jia, Damaskini Valvi, Scott M Bartell, Jiawen Carmen Chen, Thomas Inge, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Stavra Xanthakos, David E Kleiner, Rohit Kohli, Sarah Rock, Sandrah P Eckel, Michele A La Merrill, Max M Aung, Matthew P Salomon, Rob Mcconnell, Jesse Goodrich, David V Conti, Lucy Golden-Mason, Lida Chatzi

Faculty, Staff and Students Publications

Background: The rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), particularly among pediatric populations, requires identification of modifiable risk factors to control disease progression. Per- and polyfluoroalkyl substances (PFAS) have emerged as potential contributors to liver damage; however, their role in MASLD remains underexplored. This study aimed to develop a translational framework integrating human and in vitro data to elucidate the effect of PFAS on MASLD development.

Methods: We measured PFAS plasma levels in the Teen-LABS cohort (n = 136), comprising adolescents with obesity (mean age = 16.8 years) undergoing bariatric surgery. Plasma samples were also analyzed using proteomic …

Insights Into Spheroid Formation: Interaction Of Ovarian Cancer Cells With Macrophage Populations In The Tumor Microenvironment, Simone Pisano, Yajaira Sofia Jimenez, Paul Rees, Jing Xiao, Deyarina Gonzalez, Robert Steven Conlan, Bruna Corradetti

Faculty, Staff and Students Publications

Background: Treating advanced ovarian cancer (OC) is challenging due to the immunosuppressive tumor microenvironment. This study investigates tumor-immune cell interactions using organotypic spheroid models that simulate the in vivo microenvironment.

Methods: A dual-model spheroid system was established combining serous adenocarcinoma SKOV-3 cells with monocytes, pro-inflammatory (MΦ1) or anti-inflammatory (MΦ2) macrophages, or their derived exosomes (EXOs). In Model A, immune cells or EXOs were co-seeded with tumor cells to replicate early heterotypic aggregation. In Model B, immune cells or EXOs were introduced 24 h post-spheroid formation to simulate immune infiltration into established spheroids. Spheroid morphology was quantified by diameter and circularity, …

Brca2 Deficiency And Replication Stress Drive Apobec3-Mediated Genomic Instability, Kathy Situ, Abby M Green, Et Al.

2020-Current year OA Pubs

BRCA2 plays a critical role in stabilizing stalled replication forks, yet critical gaps remain in understanding how BRCA2 deficiency triggers fork collapse and drives genomic instability. Here, we identify cytidine deaminase APOBEC3B as a key driver of this process. Using a unique uracil-in-DNA probe, we show that BRCA2 loss promotes APOBEC3B-mediated uracil accumulation in single-stranded DNA (U-ssDNA) at stalled forks. These lesions when processed by UNG2 and APE1, trigger fork collapse and release ssDNA fragments into the cytoplasm, activating NF-κB signaling. This in turn upregulates APOBEC3B expression, establishing a self-reinforcing loop that amplifies cytidine deamination at stalled forks and exacerbates …

Enampt/Tlr4 Signaling Drives Pah Cellular Phenotypic Switching And Lung Vascular Remodeling, Mohamed Ahmed, Zhiyu Dai, Et Al.

2020-Current year OA Pubs

BACKGROUND: The attenuation of cellular phenotypic switchingdriving PAH vascular remodeling remains an unmet therapeutic need. As eNAMPT (nicotinamide phosphoribosyltransferase)/TLR4 signaling significantly contributes to PH pathobiology, an eNAMPT-neutralizing ALT-100 mAb was utilized to rescue monocrotaline (MCT) and hypoxia/Sugen (Hy/Su) preclinical PH rat models and to evaluate eNAMPT/TLR4 involvement in endothelial cell (EC), smooth muscle cell (SMC) and monocyte/macrophage phenotypic switching.

METHODS: MCT-PH or Hy/Su-PH rats received IgG or ALT-100 mAb (subQ, beginning week 4) with measurements of PH severity and lung tissue scRNAseq at day 42.

RESULTS: PH severity indices (hemodynamic, histologic, vascular remodeling) were significantly attenuated in MCT-PH and Hy/Su-PH …

Biofilm Formation Of A Strain Of Bovine Escherichia Coli And Analysis Of Its Influencing Factors, Xin Zhang, Yunjiao Chen, Weijuan Jia, Zhilin Liu, Zelin Jia, Jiayu Cui, Huisheng Xiong, Yuhang Zhang, Xueli Wang

The Thai Journal of Veterinary Medicine

This study investigated the biofilm (BF) formation of a bovine-derived Escherichia coli (E. coli) strain (designated DL1907) and analyzed the factors influencing its formation. The BF-forming capacity, optimal formation time and temperature, as well as the effects of different culture media, pH levels, NaCl concentrations, and glucose concentrations, were assessed using the crystal violet method. The results demonstrated that the strain had a strong BF-forming capacity, achieving the most intact BF structure after 36 h of culture at 37°C. Trypticase Soy Broth (TSB) medium promoted the strongest BF formation compared to Luria-Bertani (LB) and Müller-Hinton Broth (MH) media. …

Examining The Evolution Of Coaches Issues In Interscholastic Sport, Tyler J. Ratts, Eric W. Forsyth, Zachary C. T. Evans, James E. Johnson, Michael Fraina, Warren A. Whisenant

Global Sport Business Journal

Central to interscholastic athletic programs are coaches who directly affect the developmental outcomes experienced by student-athletes through their participation (Blanton et al., 2024; Grant, 2024; O’Boyle, 2014). Forsyth et al. (2022) analyzed the key issues perceived by athletic administrators to affect the coaching position, with Coaches Education rated as the single most important issue and Finding Coaches and Retaining Coaches also deemed to be of very high importance. Over time, the coaching role has continued to evolve, as increased role demands (Ratts, 2025), changing stakeholder expectations (Johnson et al., 2019; Stoffer et al., 2021), and growing burnout and turnover (Martin …

Sun, Fun, And Structure: What Resort Activity Schedules Reveal, Phileshia Dombroski, Ph.D., Kayla D. Mohney, Ed.D., Rebecca L. Moriarty, Ava Beal, Libby Scanlon, Emily Bailey, Cyan N. Kvacky

Proceedings of the Recreation Experience Community Network Research Symposium

Daily activity schedules are central to the guest experience in resort environments, guiding participation, communicating brand identity, and structuring leisure time. This mixed-method content analysis explored how resorts across the United States design and present these schedules, emphasizing accessibility and program diversity. Eighteen publicly available resort activity schedules were evaluated using accessibility tools (PAC 3, Adobe Acrobat, WCAG 2.2) and coded for 4,166 individual activities across eight categories. Findings revealed moderate adherence to accessibility standards. Most schedules met minimum font size and color contrast guidelines, but only 25% were compatible with screen readers and 80% lacked alternative text or structural …

Perceived Value Of Sport And Recreation In Aruba: Resident Perceptions Of Health, Lifestyle, And Physical Activity, Stephen L. Shapiro, Andy Gillentine, Jo-Anne Croes, John Wardlaw

Proceedings of the Recreation Experience Community Network Research Symposium

Sport and recreation play an important role in shaping community well-being, particularly in small island nations where health and tourism are integrated. This study examines how Aruban residents perceive the value of sport and recreation and how these perceptions vary based on the type of activity and children’s participation in these activities. A mixed-methods design was used across two phases. Phase I employed focus groups with residents, educators, and government stakeholders to explore themes of health, community impact, and education. Findings emphasized concerns over inactivity and identified sport and recreation as essential to promoting healthy lifestyles, sense of community, and …

Drivers Of Policy Support And Political Consumerism Behavior Among Water Recreationists, Mina Kim

Proceedings of the Recreation Experience Community Network Research Symposium

Individuals who engage in water-based recreation share a distinct bond with water quality due to their direct contact with aquatic environments during leisure activities. Increasing concerns about water quality have led to a rise in research exploring how environmental conditions and perceived risks shape environmental attitudes and conservation actions. However, it remains uncertain whether water recreationists extend their conservation efforts beyond those directly tied to their activities. To explore this issue, the present study investigates whether water-based recreationists in South Carolina support more stringent water management policies and engage in political consumerism behaviors, such as boycotting and buycotting. Data were …

Fall 2025 Full Issue, Undergraduate Research

PANDION: The Osprey Journal of Research and Ideas

No abstract provided.

Probiotic Intervention In Managing Chronic Stress, Bianca Opdenbosch

PANDION: The Osprey Journal of Research and Ideas

Chronic stress can induce gut dysbiosis which contributes to the dysregulation of the gut-brain axis and leads to anxiety and depressive-like symptoms. The gut-brain axis relies on nervous, immune, and endocrine interactions. Gut dysbiosis, an imbalance within the gut microbiome, disrupts gut-brain communication, impairing gut barrier integrity, inflammation regulation, and hormonal and neurotransmitter production. These gut changes contribute to mood disorders resulting from stress, and thus it is important to implement dietary interventions, like probiotics, to help mitigate these effects. Research highlights the potential of probiotics to act as an intervention to combat stress-induced gut dysbiosis and replenish beneficial bacteria …

Listening To Wrong Beliefs: Being A Virtuous Agent In Contexts Of Disparity, Madison K. Mendiola

PANDION: The Osprey Journal of Research and Ideas

Using the concept of intellectual humility (IH) described by Whitcomb et al. (2021) and their application of IH in contexts of disparity, I will be furthering the discussion of the importance of IH when engaging with the other side. Although there are intellectual harms associated with being too open-minded, and moral concerns about being a listener to harmful ideas, I argue that epistemic agents risk committing an intellectual error when they don’t try to understand the beliefs of the in-the-wrong party. Even in contexts of disparity, you should be able to understand the other party’s belief-forming methodologies, which is compatible …

Analysis Of Mct-1 Expression In Mouse Neural Retina In Response To Chronic Inflammation, Ian W. Ronson

PANDION: The Osprey Journal of Research and Ideas

Chronic inflammation is a current public health concern as it is linked to the etiology and symptoms of numerous diseases, for example diabetic retinopathy (DR). In the case of DR, inflammation leads to dysregulation of the blood retina barrier causing retinal hemorrhage and macular edema leading ultimately to irreversible vision loss. MCT-1 is critical for the survival of photoreceptor cells because MCT-1 forms protein complexes with Basigin, a cell-cell adhesion protein, that enables Müller glial cells to efficiently provide lactate as a high energy fuel source. Previous studies have shown chronic inflammation reduces Basigin expression in the retina and that …

A Descriptive Study Of Black College Students’ Perceptions Of Law Enforcement After Police Brutality, Alisia L. Collins

PANDION: The Osprey Journal of Research and Ideas

Police brutality is a social issue that has tormented the mental health of the Black community for decades. Seeing brethren battered and bruised countless times has taken an emotional toll on the relationship of the Black community with the American justice system and the officers meant to uphold it. Previous research has shown that the Black community primarily has a negative perception of law enforcement because of factors like police brutality, unjustified shootings, and legal policies within the justice system. Compounding experiences can occur for people with disabilities within the Black community. Specifically, autistic people have a higher risk of …

Popularising Semiotics (Continued)

Communication Research Trends

In the previous issue of Communication Research Trends (Vol. 11, No. 2), Keyan Tomaselli and Arnold Shepperson from the Centre for Cultural and Media Studies, University of Natal, surveyed the tangled vines of the field of semiotics and explained how, following one of the many paths through this 'forest of symbols', they are trying to develop semiotics into an instrument of social and cultural criticism and reform.

In the present number (11/3) of Communication Research Trends the same discussion is continued through a series of individual book reviews contributed by both senior and junior members of the same Centre. Again, …

Analyzing The Characteristics Of Highly Educated Unemployment In Indonesia’S Capital City, Febrim Leksiando Sipayung, Andy Fefta Wijaya, Fadillah Putra, Natsumi Aratame

Jurnal Ekonomi dan Studi Pembangunan

Indonesia’s capital city, Jakarta, is facing a problem of highly educated unemployment, a phenomenon that has become a very serious issue as Indonesia's population continue to increase facing the demography dividend. This study aims to analyze the characteristics of highly educated unemployment in Jakarta. The logistic regression model is used to analyze the labor force associated to important aspects such as highly educational attainment, age, gender, marital status, and status in the household. This study finds that being less-educated, young, male, single, and member of the household respectively increase the probability of being unemployed. However, it also finds that total …

Technical Efficiency Analysis Of Msmes Fashion Offline And Online In Surabaya, Atik Purmiyati, Tamat Sarmidi, Reza Pradipta

Jurnal Ekonomi dan Studi Pembangunan

The main purpose of this study is analyzing the level of technical efficiency of MSMEs fashion offline with offline and online in Surabaya, examine the differences between offline with offline and online, and determine the factors that affect technical efficiency. This study uses purposive sampling method with primary data. Non-parametric and parametric approach used with Data Envelopment Analysis, Independent sample T-Test and Tobit Regression. First, the results showed the average level of technical efficiency of offline MSMEs fashion was 65 percent with 8 efficient businesses. Meanwhile, the average level of technical efficiency of online and offline MSMEs fashion is 77.1 …

“A Place, A Spirit, A Ministry”: The Persistence Of Koinonia Farm In The Post-Jordan Years, Ryan Geockner

Communal Societies

No abstract provided.

Enhancing Green Energy Solutions Through Pemfc: A Comprehensive Review Of Modeling, Efficiency, Performance Metrics, And Future Opportunities, Elaf N. Mahrous, Ahmad Jamal, Muhammad Saleem

Yanbu Journal of Engineering and Science

Polymer Electrolyte Membrane Fuel Cells (PEMFCs) are a promising technology for clean and efficient energy production. PEMFC was initially developed for the space programs in the 1960s, but today, it finds its application in numerous engineering applications. Growing concerns about fossil fuel depletion and global warming, along with recent advances in renewable energy and the hydrogen economy, have further supported its development. This comprehensive review consolidates modeling approaches, performance analyses, thermal management strategies, and future prospects of PEMFC technology. The analysis of the characteristics of Voltage-Current (V-I) and subsequent examination of the fuel cell’s efficiency include the evaluation of thermal …