Digital Commons Network^™

Molecular Pathway Dysregulation In Chronic Liver Disease: Metabolic And Mechanotransductive Drivers Of Hepatic Pathophysiology, Samantha Harvat

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Metabolic dysfunction–associated steatotic liver disease (MASLD) represents a rapidly growing cause of chronic liver injury, yet the molecular interactions linking metabolic stress, inflammation, fibrosis, and hepatocellular carcinoma (HCC) remain incompletely defined. This thesis integrates transcriptomic analyses across multiple GEO datasets to identify coordinated metabolic, inflammatory, and mechanotransductive pathways that collectively drive disease progression.

Analysis of human liver biopsy datasets (GSE126848 and GSE89632) revealed consistent suppression of glycolysis, β-oxidation, and oxidative phosphorylation across MASLD and MASH samples, accompanied by modest compensatory TCA cycle activation. These alterations reflect impaired metabolic flexibility, mitochondrial stress, and increased ROS susceptibility. Concurrently, cytokine-network enrichment demonstrated activation …

Curb Their Enthusiasm: Controlling The Discretion Of Creative Prosecutors, Scott A. Schumacher

The University of New Hampshire Law Review

No abstract provided.

An Evaluation Of Virtual Supervision Effectiveness Within Department Of Veterans Affairs (Va) Health Professionals Training Programs, Linda M. Kawentel, John P. Donnelly, Kaylee W. Burgan, Gezan M. Yahya, Joanna S. Doredla, Jessica L. Johnson, Kimberly Falco, Marjorie A. Bowman, John Byrne, Nicholas W. Bowersox

Population and Public Health Sciences Faculty Publications

Background Limited information exists on whether virtual training is equivalent to traditional in-person training in supporting the development of clinical providers. Methods A multi-site evaluation using survey methods was conducted with a multidisciplinary group of health professions trainees and supervisors within the Veterans Health Administration to assess the equivalence of two supervision modalities – exclusively in-person supervision and supervision incorporating at least some virtual supervision – on trainee clinical competency development, trainee preparedness to respond to patient emergencies, and effective trainee/supervisor working relationships. Results Trainees who experienced some virtual supervision rated their clinical competency levels as higher than trainees with …

Behind Closed Doors, Beyond The Cell: Supporting Children Of Incarcerated Parents, Averi R. Amaro

Honors Program Theses and Research Projects

This study examines the overlooked population of children affected by parental incarceration and evaluates intervention programs designed to support them. Grounded in Labeling Theory (Becker, 1963), Self-Fulfilling Prophecy (Merton, 1948), and the Restorative Justice framework (Zehr, 2002), this study explores how stigma, expectation, and repair shape the outcomes for the youth affected by parental incarceration. Drawing from qualitative and quantitative research, it analyzes the emotional, social, and educational effects of incarceration on families, identifying protective factors such as attachment, mentoring, and community support that mitigate delinquency risks. Program evaluations of Girl Scouts Beyond Bars, Parenting Inside Out, Project Avary, and …

Lived Experiences And Educational Needs Of Women With A History Of Preeclampsia: A Qualitative Phenomenological Study In Indonesia, Fitriana Fitriana, Ani Kristianingsih, Nopi Anggistaputri

Journal of Asian Midwives (JAM)

Background: preeclampsia (PE).\ is one of the leading causes of maternal morbidity and mortality worldwide Many pregnant women fail to recognize early warning signs of the condition despite attending antenatal care, for reasons such as limited understanding of PE symptoms and/ or inadequate communication of health information by healthcare providers. Women with a previous history of PE are particularly vulnerable and require targeted educational support during subsequent pregnancies.
Methods: Eight pregnant women with a documented history of PE in their second or third trimester participated in in-depth semi-structured interviews using an interpretative phenomenological technique.  To ensure credibility and reliability, the …

Factors Associated With Emergency Hospitalization Of Kidney Disease Patients In A National Hospital Kenya., Dorcus Miyombe

MSc in Advanced Practice Nursing

Introduction: Emergency hospitalizations among End Stage Kidney Disease (ESKD) is a major global health burden, with low- and middle-income countries in sub-Saharan Africa (SSA), experiencing the highest rates of morbidity and mortality. Limited resource, economic burden, and insufficient health infrastructure were the main challenges. Emergency hospitalizations at Kenyatta National Hospital remains high due to systemic gaps and poor continuity of care. Prerenal, intrarenal, post-renal injuries, as well as any combination of these, are the primary causes of ESKD. There are stipulated guidelines for ESKD patients’ management however, realization of these goals has not been achieved leading to hospitalization KDIGO …

Community Health Promoters’ Experiences In Mitigation Of Cardiovascular Diseases In Lari Sub-County - Kiambu County, Kenya, Emily Njeri Muchina

MSc in Advanced Practice Nursing

Background: Cardiovascular diseases (CVDs) are a rising public health issue in low- and middle-income countries, including Kenya, where there is an escalation of their deaths and preventable risk factors. Community health promoters (CHPs) have a crucial role in the prevention of CVDs. Yet, low knowledge of CVD prevention and low detection of CVD risk factors characterise most underserved communities in Kenya. Little has been documented about CHPs' experiences in mitigating CVDs despite the presence of multilevel barriers and facilitators that can shape their experiences.

Aim: To gain an in-depth insight into the experiences of CHPs in mitigating CVD …

Predictors Of Complications Among Adult Patients Diagnosed With Type 2 Diabetis Mellitus At Thika Level Five Hospital, Kenya, Bernard Wambua Mbithi

MSc in Advanced Practice Nursing

Introduction: Despite advances in the management of Type 2 diabetes mellitus (T2DM), anecdotal reports from Thika Level Five Hospital indicate that patients still present with diabetes mellitus-associated complications. Therefore, this research aimed to determine the predictors of complications among adult patients diagnosed with T2DM in the hospital.

Methodology: Analytical cross-sectional design was utilized in this research. To select the respondents, purposive sampling was used to recruit six nurse managers and their deputies (making a total of 12 nurses), while 294 patients in the clinic were recruited using systematic sampling. Purposive sampling was also used to recruit 15 patients …

Rapid Microbial Activity In Marine Sediments Significantly Enhances Silica Cycling Rates Compared To Abiotic Processes, Panagiotis Michalopoulos, Jeffrey W. Krause, Rebecca A. Pickering, Eleni Rousselaki, Kanchan Maiti, Martial Taillefert, Christophe Rabouille, Rudolph Corvaisier

Faculty Publications

Silicon, earth’s second most abundant element, cycles via biogeochemical processes in terrestrial and oceanic environments. The marine sediment-water interface is thought to divide biological-dominated (water) from abiotic-dominated (sediment) silica cycling processes. Studies indicate marine extremophile bacteria induce silica precipitation, but the quantitative importance of microorganisms in broader sediment silica cycling remains unexplored. We hypothesize that microorganisms significantly influence sediment silica cycling, challenging the prevailing divide of microbial importance. Within hours, sediment microbes expedited silica sequestration through rapid coupled dissolution/reprecipitation processes in marine deltaic sediment experiments. Using radiotracer silicon-32, we reveal that microbial mediation enhanced silica uptake, surpassing abiotic uptake by …

Elucidating The Role Of Marine Benthic Carbon In A Changing World, Cristina Schultz, Jessica Y. Luo, Damian C. Brady, Robinson W. Fulweiler, Matthew H. Long, Colleen M. Petrik, Jeremy M. Testa, Heather M. Benway, David Burdige, Marta M. Cecchetto, Isa Elegbede, Natalya Evans, Alexandra Frenzel, Kayla Gillen, Lisa C. Herbert, Heidi K. Hirsh, Gennadi Lessin, Lisa Levin, Kanchan Maiti, Sairah Malkin, Sarah L. Mincks, Stanley Nmor, Anh Pham, James Pinckney, Christophe Rabouille, Shaily Rahman, Subhadeep Rakshit, Nicholas E. Ray, Dalton K. Sasaki, Samantha A. Siedlecki, Christopher Somes, Aron Stubbins, Olivier Sulpis

Faculty Publications

The ocean plays a major role in controlling atmospheric carbon at decadal to millennial timescales, with benthic carbon representing the only geologic-scale storage of oceanic carbon. Despite its importance, detailed benthic ocean observations are limited and representation of the benthic carbon cycle in ocean and Earth system models (ESMs) is mostly empirical with little prognostic capacity, which hinders our ability to properly understand the long-term evolution of the carbon cycle and climate change-related feedbacks. The Benthic Ecosystem and Carbon Synthesis (BECS) working group, with the support of the US Ocean Carbon & Biogeochemistry Program (OCB), identified key challenges limiting our …

Hurricanes And Human Health In Louisiana: Insights From Hurricanes Laura, Delta, And Ida, Shobha Kumari Yadav, Robert V. Rohli, M. E. Betsy Garrison, Elisabeth Ponce-Garcia, Nazla Bushra, Charleen Mcneill

Faculty Publications

Louisiana is one of the most disaster-prone states, with hurricanes ranking among the most destructive hazards. Hurricanes impede sustainability by straining hospital infrastructure, overwhelming emergency departments, and disrupting continuity of care. Louisiana’s healthcare system, characterized by high uninsured rates, limited rural access, and notable racial and socioeconomic disparities, is particularly vulnerable during disasters. This research explores trends of mental and respiratory health in Louisiana surrounding Hurricanes Laura (2020), Delta (2020), and Ida (2021). Analysis reveals a substantial increase in admissions after landfall of all three storms, with mental health conditions showing a larger surge than respiratory ones in already-vulnerable communities. …

Exploring Retention And Satisfaction Among Arkansas County-Level Cooperative Extension Employees: A Job Embeddedness Perspective, Rebecca M. Simon

Graduate Theses and Dissertations

Abstract This quantitative study investigated the retention of county-level employees within the Arkansas Cooperative Extension Service (CES) using Job Embeddedness Theory (JET) as the theoretical framework. The research aimed to describe levels of job embeddedness, job satisfaction, and intent to stay, and to examine the relationships among these variables. A census of 328 CES employees was conducted, yielding a 53% response rate. Data were collected through a validated online survey and analyzed using descriptive statistics, correlation analysis, and multiple regression. Results indicated high scores in organizational fit and sacrifice dimensions, while links to organization and community were comparatively lower. Age …

The Banner - V. 160, No. 10 - (December 2025), Christian Reformed Church In North America

The Banner

No abstract provided.

Masthead

UC Law Journal

No abstract provided.

An Introduction To The Ai Special Issue And A Modern Framework For Ai In Sport Management, Jun Woo Kim, Vitaly Ford

Journal of Applied Sport Management

This paper introduces the special issue while also exploring the theoretical foundations and practical applications of AI in sport management, guided by Artificial Intelligence: A Modern Approach (Russell & Norvig, 2021). The manuscript examines AI’s evolution from rule-based systems to large language models (LLM)–driven intelligent agents and classifies the technology into five major subfields—machine learning, natural language processing, computer vision, reinforcement learning, and AI agency. Using real-world sport industry examples and recent academic research, this paper presents a modern taxonomy of AI’s role in sport management, articulates managerial implications, and outlines future research directions necessary for sustainable and ethical integration …

An Autoethnography: How Professional Organizations Serve As Professional Development For Secondary Journalism Teachers, Mark R. Hilburn

Educational Leadership Theses, Dissertations, and Student Creative Activity

The purpose of this autoethnography is to provide analysis and explain the importance of professional development experiences for secondary teachers, especially for those that are singletons in a school, district, or community.

Autoethnography is a qualitive research method in which the researcher is also the subject of the study. In autoethnography, the researcher uses autobiographical stories to analyze and interpret their lived experiences with the purpose of extending sociological understanding. It reflects the interconnectivity of self, others, and culture (Hamdan, 2012).

Effective professional development is typically long-term, collegial, supported by leadership, and context-specific (Richardson, 2003; Sparks, 2002), and essential for …

Lack Of Multidisciplinary Collaboration In Stroke Rehabilitation In Pakistan: A Call For Integrated Care Models, Etisam Wahid, Shahzad Ahmad, Nimrah Humayoon

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Fall 2025 Faculty Senate Newsletter, Faculty Senate

Faculty Senate Newsletter

No abstract provided.

December 2025 Title Changes & Checking In, Willa Tavernier

NASIG Newsletter

No abstract provided.

An Analysis Of Face Synthesis Methods And Their Influence On Human Perception, Maha Habib Almaimani

All Dissertations

Synthetic faces (e.g., computer-generated characters) have been increasingly utilized across various fields, including entertainment, healthcare, and education. Perceptual studies are often conducted to understand how synthetic faces are perceived by humans, aiming to enhance both quality and user experience in these domains. Over the years, numerous methods have been developed to create synthetic faces, ranging from traditional techniques such as image composites, Active Appearance Models, and 3D Morphable Models to more recent machine-learning-based frameworks like Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs).

Despite the growing adoption of synthetic face generation and the variety of algorithms available for their creation, …

Gender And Consensus On The Courts, Kaleigh A. Ruiz

Michigan Journal of Gender & Law

During group deliberation, women tend to be the harbingers of compromise, vying for consensus on even the most contentious topics. However, women cannot succeed in this endeavor if gender bias prevents their voices from being heard. In federal courts, collaboration is essential to reaching the simple majority needed to resolve a case. While the courts already function under norms of collegiality during deliberations, the practice of writing a separate opinion to acknowledge disagreement with a majority opinion remains relatively common. In this Article, I test two competing theories as to the effects of women judges on consensus. On one hand, …

Program Development And Evaluation & Clinical Skills Of A Comprehensive Screening Tool For The Pediatric Population, Keegan S. Lepkowski

Occupational Therapy Doctoral Capstones

This capstone project focused on occupational therapy screening tools for the pediatric population within the areas of specialization of program development and evaluation and clinical skills. The literature revealed that there is a lack of recognition of the intent, knowledge, and access to screening and how it fits within the overall evaluation process. To address this gap, this capstone project aimed to create a positively perceived comprehensive screening tool for occupational therapy clinicians to utilize for the early identification of developmental delays within preschool-aged children. This capstone project also aimed to organize a screening program in coordination with local schools/daycare …

Leadership Development Programs For Elected Officials: Measuring The Impact Of Extension On County Leadership Capacity, Nathan Palardy, Matthew Sowcik

Journal of Human Sciences and Extension

Although Extension-led leadership development programs for elected officials are widespread, few evaluations assess their effectiveness. This study uses 2 years of survey data to quantitatively and qualitatively evaluate several programs for Florida county commissioners, focusing on reaction, knowledge transfer, and behavior change. Results indicate high satisfaction with the program content and quality and substantial improvement in leadership competencies. Commissioners reported frequent application of the skills taught and cited networking opportunities as a key benefit. Findings suggest that Extension-led programs can strengthen local governments by enhancing the leadership capabilities of elected officials and offering insights to guide the design of similar …

The Power Of Core Memories In Financial Education For Gen Alpha Children, Karen Richel

Journal of Human Sciences and Extension

Financial education plays a critical role in shaping lifelong financial behaviors and decision-making skills. To create a lasting impact, it is essential to establish core memories associated with money management from an early age. This article explores the significance of these foundational experiences and their role in financial education for Gen Alpha children.

A series of eight immersive financial education events was developed to meet state and national standards for students in pre-kindergarten through sixth grade. These events employ play-based and object-based learning approaches, immersing students in engaging, age-appropriate activities that incorporate real-world scenarios. By creating a fun and memorable …

Enhancing Youth Learning Outcomes Of Travel Programs Through Storytelling, Gary Ellis, Parisa Paymard, Dottie Goebel, Darlene Locke, William F. Zanolini, Emily Catalan, Kelley Ranly

Journal of Human Sciences and Extension

We conducted two studies to evaluate strategies that Extension educators may use to enrich youth travel program experiences. Study 1 evaluated the effects of telling stories about attractions before site visits on youth experiences and learning outcomes on site. Seventeen youth in a 4-H program designed to promote cultural understanding visited eight attractions in Costa Rica. The evening before visiting three sites, youth were told a fictional or cross-fictional story about the sites. The stories elicited imaginary travel to the site (narrative transportation). After visiting the sites, the youth reported the extent to which they felt like they were in …

Evaluating The Effectiveness Of Relationship Education For Latino Adolescents, Joshua J. Turner, Esra Şahin, Kay Bradford, Brian J. Higginbotham

Journal of Human Sciences and Extension

Adolescent romantic relationships are often characterized as exploratory and fleeting; however, they have lasting impacts on individual well-being and relationship quality during and beyond adolescence, shaping future relationship expectations and quality (Collins, 2003; Madsen & Collins, 2011). Adolescent relationship education is an important programmatic feature under the broader umbrella of family life education (Simpson et al., 2018). Previous evaluative studies document positive outcomes in educating adolescents on how to build and recognize healthy relationships (Bradford et al., 2023; Kerpelman et al., 2010); however, research remains limited in addressing potential benefits for adolescents from historically underrepresented groups. This study addresses this …

Referral Strategies For Recruitment And Engagement Of Community Adults Into Online Extension Health Programs, Cheryl L. Eschbach, Dawn A. Contreras, Holly B. Tiret

Journal of Human Sciences and Extension

This article shares details behind building organizational capacity to establish program referrals for statewide recruitment of community adults into Cooperative Extension’s online health programs. This study explores the role of intentional recruitment strategies (active and passive) to increase participant program enrollment into health education and shares examples from one state that has created a trained workforce that offers ongoing research- and evidence-based programs. After many years of trying paper, phone, and electronic medical record methods to increase program reach, Michigan State University Extension tried an electronic referral process via a QR code and web link, accompanied by program marketing, to …

Teaching Leadership In The Context Of Crisis: Connecting Organizational Leadership And Crisis Competencies In A Faculty Leadership Education Program, Caitlin Lunzmann, Nicole Lamee Perez Stedman, Matthew Sowcik

Journal of Human Sciences and Extension

This research focused on enhancing leadership instruction in colleges of agriculture. A multi-institutional research team initiated a program to teach agricultural and natural resource faculty how to create leadership-oriented case studies for undergraduates. Forty faculty members participated in an online training academy centered on Bolman and Deal’s Organizational Frames and case study writing. Following the academy, these faculty members participated in field experiences in the southeastern U.S. to gather data on natural disasters, which they used to write case studies about leadership in agriculture. Though the program focused on organizational leadership, it also discussed leadership in the context of natural …

Exploring The Educational Needs Of Family Caregivers For Patients With Dementia, Karen L. Franck, Janet Fox, Ann A. Berry, Kristen Johnson, Jessica Taylor, Matt Devereaux

Journal of Human Sciences and Extension

Family members who care for patients diagnosed with Alzheimer’s and dementia often face significant stressors and challenges that impact their quality of life. As part of a project to develop Extension educational materials and resources specifically for family caregivers, we conducted an online needs assessment survey with 196 adults in the U.S. Participants identified doctors, the internet, and caregiver support groups as top sources of information about dementia. They were interested in strategies to help them manage stress, address patient behavioral issues, and access locally available resources. Furthermore, they were interested in attending educational programs with other caregivers. These findings …

The Wisdom-Ing Of Academia: A Servant-Leadership Perspective, Kathleen Patterson, Jeffrey Brauch, Don Finn, David Wallace, Jeffrey Anderson, Dorothy Hargett

International Journal of Servant-Leadership

This article looks at the wisdom-ing of academia as more faculty members choose to delay retirement, continue working in varied ways, and are vibrant to the academy. Robert K. Greenleaf (1998), who is best noted as the Father of Servant Leadership, called aging the ultimate test of spirit. The authors represent Regent University’s Faculty Senate and look at this wisdom-ing, or graying, of faculty members through a Servant Leadership lens, a Biblical perspective, and then cognitive considerations, to provide insight into higher-education at large. We, the Regent University Faculty Senate, then share insights we learned from anecdotal casual conversations with …