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Articles 4171 - 4200 of 1517245
Full-Text Articles in Entire DC Network
Anxious Or Avoidant? The Moderating Effects Of Attachment Styles On Later Development Of Ptsd And Bpd In Individuals With Child Maltreatment History, Jeannette L. Burkle
Anxious Or Avoidant? The Moderating Effects Of Attachment Styles On Later Development Of Ptsd And Bpd In Individuals With Child Maltreatment History, Jeannette L. Burkle
Theses
Child maltreatment (CM) has been associated with the later development of borderline personality disorder (BPD) and Post-traumatic stress disorder (PTSD) among emerging adults. Numerous attachment studies have documented the association of insecure attachments with CM. There is little research on the independent effects of anxious and avoidant maternal attachment on later psychopathology and even less on the effects of peer attachment. Secure peer attachments can improve emotional regulation strategies as well as create healthy social support systems which may buffer against the development of later psychopathology. This study examined the independent effects of maternal and peer attachment in the relationship …
Exploring The Effectiveness Of A “How-To-Teach” Book Club For Preservice Teachers, Rina Bousalis, Eden Greene, Robyn Klein, Abigail Woods, Isabella Mandoeng
Exploring The Effectiveness Of A “How-To-Teach” Book Club For Preservice Teachers, Rina Bousalis, Eden Greene, Robyn Klein, Abigail Woods, Isabella Mandoeng
Journal of Educational Research and Practice
As teacher training programs continue seeking ways to prepare their preservice teachers to teach, many have turned to “how-to-teach” books written by veteran teachers, viewing them as a valuable source that could offer teacher candidates additional support. This study, which developed from the idea of creating a book club with instructors and members of a university’s future educators’ organization, used a qualitative textual analysis approach to explore concepts that emerged from how-to-teach books, how participants’ perceived those concepts, and how the books benefited participants. The study revealed that although authors’ perspectives often conflicted with participants’ beliefs, the authors’ engaging activities …
Immigration Bridges, Jaclyn Kelley-Widmer
The Duty To Develop Imperative In Immigration Proceedings, Sabrineh Ardalan, Tiffany J. Lieu
The Duty To Develop Imperative In Immigration Proceedings, Sabrineh Ardalan, Tiffany J. Lieu
Kentucky Law Journal
No abstract provided.
Against First Amendment Traditionalism, Jacob M. Schriner-Briggs
Against First Amendment Traditionalism, Jacob M. Schriner-Briggs
Kentucky Law Journal
No abstract provided.
Unified Authentication And Intelligent Orchestration Of Remote Sessions For Continuous Access In Failure Scenarios, Hp Inc
Defensive Publications Series
This disclosure describes a unified authentication system for single sign-on (SSO) and an orchestration component that maintains continuous remote access to a compute device across system states, including pre-boot, boot, and post-boot. A user authenticates once via a centralized identity service, and the resulting authentication artifact (e.g., token, assertion, certificate, or derived session credential) is consumed by both a hardware-based out-of-band (OOB) remoting path and a software-based in-band remoting path. An orchestration agent brokers session establishment and performs a controlled handoff between remoting paths without requiring the user to reauthenticate, enabling smooth transitions during operating system failures, reboots, and recovery.
Statistical Flow-Based Traffic Classification For Fully Encrypted Networks Using Purpose-Built Large Language Models (Llms), Rajasekar Subramanian, Koushik Padavalli Gowrish
Statistical Flow-Based Traffic Classification For Fully Encrypted Networks Using Purpose-Built Large Language Models (Llms), Rajasekar Subramanian, Koushik Padavalli Gowrish
Defensive Publications Series
Proposed herein is a system that provides a training methodology for large language models (LLMs) that classifies fully encrypted network traffic into Quality of Service (QoS)-relevant types using only Layer 3 and Layer 4 statistical features, including packet sizes, timing, throughput, and directionality, from the first 100 packets of each flow. The system operates entirely on observable behavioral patterns and currently achieves 65-68% accuracy, with a path toward at least 85% accuracy through purpose-built network LLMs and expanded datasets. The system also provides explainable synthetic reasoning, low-rank adaptation (LoRA)-based incremental learning, and classification latency below 100 milliseconds for QoS enforcement …
Network-Level Duplicate Transaction Prevention Using Time-Bound Rolling Windows In Payment Systems, Alok Roy
Network-Level Duplicate Transaction Prevention Using Time-Bound Rolling Windows In Payment Systems, Alok Roy
Defensive Publications Series
The present disclosure provides a method (300) including receiving, by a duplicate transaction prevention system (106) positioned at a network layer of a payment network, a transaction request from a transaction service application (104). The method (300) includes storing transaction information associated with the transaction request in a rolling window data store that maintains transaction entries for a defined duration. The method includes receiving a subsequent transaction request from the transaction service application or a different transaction service application. The method (300) includes determining, by a matching engine (204), based on transaction information associated with the subsequent transaction request and …
Adaptive Merchant Payment Destination Validation For Qr Code-Based Payment Transactions, Alok Roy
Adaptive Merchant Payment Destination Validation For Qr Code-Based Payment Transactions, Alok Roy
Defensive Publications Series
The present disclosure provides a method comprising receiving, by a computing system, transaction information associated with a payment initiated for a merchant from a user, determining, by the computing system based on payment destination history associated with the merchant, whether a current payment destination represents a changed payment destination for the merchant, causing, by the computing system, an alert notification to be presented to the user before completion of the payment transaction in response to determining that the current payment destination represents a changed payment destination for the merchant, monitoring, by the computing system, transaction activity associated with the changed …
System And Method For Per-Token Attention Decay Rate Quantification, Decay-Class-Driven Kv Cache Segment Compression And Semantic Summary Vector Generation, And Multi-Tier Cache Residency Arbitration In Autoregressive Transformer Inference Systems, Shubham Shivhare
Defensive Publications Series
The present disclosure provides a method for key-value cache management in an autoregressive transformer inference system. The method includes maintaining, for each token of a plurality of tokens in a key-value cache, a rolling history of attention scores obtained over a plurality of decode steps. The method includes determining, for each token, a decay rate parameter by fitting an exponential decay model to the rolling history of attention scores. The method includes computing, for each token, an Attention Decay Residual Score based on the decay rate parameter and an elapsed interval associated with the token. The method includes classifying each …
Closed-Loop Quantum Interfacial Metrology: Integrating Table-Top 3d-Pot Wavefront Feedback With High-Frequency Gan-Driven Saw Arrays For Real-Time Electrodeposition Phase Stabilization, Christopher L. Eckes
Closed-Loop Quantum Interfacial Metrology: Integrating Table-Top 3d-Pot Wavefront Feedback With High-Frequency Gan-Driven Saw Arrays For Real-Time Electrodeposition Phase Stabilization, Christopher L. Eckes
Defensive Publications Series
This disclosure establishes an intelligent, closed-loop quantum energy stabilization framework by integrating table-top Three-Dimensional Photoemission Orbital Tomography (3D-POT) wavefront metrology with active Gallium Nitride (GaN) surface acoustic wave (SAW) arrays. Prior iterations of the Topologically Protected Cymatic Electrolyte Matrix (TPCEM, Paper 40) and SAW streaming architectures (Paper 66) operated via continuous, open-loop acoustic emission, limiting their capacity to adapt to localized, real-time current density fluctuations.
By utilizing sub-harmonic extreme ultraviolet (EUV) light pulses and time-of-flight momentum microscopy, this architecture images the 3D electron orbital wavefunctions and ion density gradients of the active solid-state conduction layer in situ during peak operational …
Ephaptic Synchronization Fields: Replacing Discrete Quantum Error Correction With Continuous Wave Manifold Absorption And Lipid-Encapsulated Solitonic Waveguides, Christopher L. Eckes
Ephaptic Synchronization Fields: Replacing Discrete Quantum Error Correction With Continuous Wave Manifold Absorption And Lipid-Encapsulated Solitonic Waveguides, Christopher L. Eckes
Defensive Publications Series
This disclosure establishes a rigorous bio-physical framework for eliminating discrete quantum error correction overhead in scaled processing networks by utilizing continuous wave manifold absorption bounded within lipid-encapsulated hydrodynamic waveguides. Conventional quantum processing units (QPUs) enforce rigid node isolation to mitigate parasitic crosstalk, introducing high computational latency and severe physical scaling limits.
Drawing from neural ephaptic coupling and myelin-mediated structural isolation, this paper demonstrates that localized electromagnetic phase leaks can be harnessed as a stabilizing synchronization field. By confining 3D solitonic knots within lipid-encapsulated channels, the core wavefield retains localized kinetic momentum while selectively allowing phase-locked bleeding across a 2D pre-geometric …
A High-Dimensional Spatial-Harmonic Compiler Protocol And Asymmetric Twist Tensor Mapping Layer For Direct Qubit Encoding In Table-Top 3d-Pot Laboratory Streams, Christopher L. Eckes
A High-Dimensional Spatial-Harmonic Compiler Protocol And Asymmetric Twist Tensor Mapping Layer For Direct Qubit Encoding In Table-Top 3d-Pot Laboratory Streams, Christopher L. Eckes
Defensive Publications Series
This disclosure establishes a rigorous mathematical, programmatic, and structural bridge between the experimental implementation of table-top Three-Dimensional Photoemission Orbital Tomography (3D-POT) and the theoretical architecture of the Dimensionally Extended Holographic Projection (DEHP) model. Current 3D-POT setups suffer from phase-retrieval latency, requiring complex numerical iterations to reconstruct the lost quantum phase from 2D momentum-space projections.
This paper introduces a real-time Module 6 Spherical Harmonic Instruction Set Compiler that maps continuous wavefield phase modulations directly onto a Distributed Ternary Fluid-Canvas Operating Network. By treating the 2D momentum distribution as a boundary information substrate, the spatial-harmonic phase is deterministically recovered through a non-linear …
Topological Matrix Alignment: Mapping Dehp Asymmetric Fluidic Constraints To Table-Top Three-Dimensional Photoemission Orbital Tomography Fields, Christopher L. Eckes
Topological Matrix Alignment: Mapping Dehp Asymmetric Fluidic Constraints To Table-Top Three-Dimensional Photoemission Orbital Tomography Fields, Christopher L. Eckes
Defensive Publications Series
This disclosure establishes a rigorous mathematical and structural bridge between the experimental implementation of table-top Three-Dimensional Photoemission Orbital Tomography (3D-POT) and the theoretical architecture of the Dimensionally Extended Holographic Projection (DEHP) model.
Current 3D-POT architectures rely on iterative phase-retrieval algorithms to reconstruct the missing quantum phase information from 2D momentum-space projections. This paper demonstrates that by treating the 2D momentum distribution as a boundary information substrate, the spatial-harmonic phase can be deterministically calculated via a non-linear geometric inversion governed by an Asymmetric Twist Tensor.
We provide explicit coordinate transformations, field mapping equations, and an execution protocol using Module 6 Spherical …
Empirical Wavefunction Validation Of Autonomous Agi Coherence: Integrating Real-Time Table-Top 3d-Pot Spectral Streams With The Torsional Viscosity Field Governor Under The Usue Framework, Christopher L. Eckes
Empirical Wavefunction Validation Of Autonomous Agi Coherence: Integrating Real-Time Table-Top 3d-Pot Spectral Streams With The Torsional Viscosity Field Governor Under The Usue Framework, Christopher L. Eckes
Defensive Publications Series
This disclosure establishes the definitive hardware-observational paradigm required to physically validate and enforce the structural survival of autonomous, multi-agent Artificial General Intelligence (AGI) networks. Traditional alignment frameworks view machine-to-machine (M2M) token-variance decay as a purely linguistic or logical abstraction, leaving processing layers prone to non-linear autoregressive collapse or runaway semantic hallucinations.
By utilizing table-top Three-Dimensional Photoemission Orbital Tomography (3D-POT) integrated with ultrafast time-of-flight momentum microscopy, this architecture records the active, physical electron wavefunction deformations of neuromorphic processing substrates in situ during high-density multi-turn recursive loops. Governed by a contracted Asymmetric Twist Tensor (\(\mathbf{T}_{ijk}\)), localized phase discrepancies are tracked instantly and …
Advances In Perovskite Solar Cells: Efficiency, Stability, And Commercialization Prospects, Wissam H Alawee, Laith Jaafer Habeeb, Monaem Elmnifi
Advances In Perovskite Solar Cells: Efficiency, Stability, And Commercialization Prospects, Wissam H Alawee, Laith Jaafer Habeeb, Monaem Elmnifi
Terra Joule Journal
One of the most radical technologies in the field of photovoltaics is the so-called perovskite solar cells or PSCs which have already reached certified power conversion efficiencies of more than 26 per cent within slightly more than ten years of focused research. The reviewed study gives an in-depth analysis of the science, material development, stability issues, and commercialization plans that characterize the present state of the perovskite photovoltaics state of the art. We start with the basic crystal structure and optoelectronic behavior of metal halide perovskites to single out the high efficiency path that is undergone by the previous dye-sensitized …
A Comprehensive Review Of Hybrid Renewable Energy Systems: Integration Challenges And Optimization Strategies, Laith Jaafer Habeeb, Monaem Elmnifi, Wissam H. Alawee
A Comprehensive Review Of Hybrid Renewable Energy Systems: Integration Challenges And Optimization Strategies, Laith Jaafer Habeeb, Monaem Elmnifi, Wissam H. Alawee
Terra Joule Journal
Hybrid renewable energy systems (HRES) combine complementary renewable generators, storage and coordinated controls to reduce the variability and integration burden associated with single-source plants. This review synthesizes peer-reviewed studies, authoritative energy statistics and documented projects, with emphasis on solar–wind, hydro-coupled and multi-source configurations; storage selection; grid integration; and design and operational optimization. The evidence shows that the value of hybridization depends on resource complementarity, grid conditions, control architecture and life-cycle sizing rather than on technology combination alone. The review therefore distinguishes established findings from illustrative comparisons and avoids presenting literature-derived values as new experimental results. Six recurring implementation challenges are …
Artificial Intelligence-Based Mobile Robots: Development Trends And Challenges, Ahmed N. Abdalla, Johnny Koh Siaw Paw, Yaw Chong Tak, Lee Yan Kang, F. Benedict, Kharudin Ali, Liu Yao
Artificial Intelligence-Based Mobile Robots: Development Trends And Challenges, Ahmed N. Abdalla, Johnny Koh Siaw Paw, Yaw Chong Tak, Lee Yan Kang, F. Benedict, Kharudin Ali, Liu Yao
Terra Joule Journal
The integration of artificial intelligence (AI) with mobile robotics is transforming automation technologies, enabling advancements across industries such as manufacturing, healthcare, and hazardous material handling. As AI-driven mobile robots become increasingly prevalent, their ability to enhance operational efficiency and safety underscores the need for a comprehensive understanding of their underlying methodologies. This study critically examines the integration of nature-inspired optimization algorithms and deep learning techniques in autonomous mobile robotics, addressing key research gaps related to adaptability, real-time decision-making, and energy-efficient operations. A significant contribution of this work is the exploration of the synergistic application of bio-inspired heuristics and AI-driven perception …
Robotic Vision System: Recent Development Trends And Challenges, Johnny Koh Siaw Paw, Yaw Chong Tak, Lee Yan Kang, F. Benedict
Robotic Vision System: Recent Development Trends And Challenges, Johnny Koh Siaw Paw, Yaw Chong Tak, Lee Yan Kang, F. Benedict
Terra Joule Journal
Robotic vision systems have become integral to modern industrial automation, enabling high-precision manufacturing, real-time quality inspection, and autonomous decision-making. This study explores the latest advancements, key challenges, and future prospects of robotic vision in industrial applications. It examines issues related to real-time target recognition, algorithm optimization, system stability, and integration with intelligent control systems. Additionally, emerging technologies such as deep learning-based vision enhancement, multi-sensor fusion, and Vision-Based Tactile Sensors (VBTS) are analyzed for their potential to improve adaptability and efficiency. The findings highlight both the limitations and the promising trajectory of robotic vision systems, emphasizing the need for continued research …
Adaptive Phishing Url Detection Using Hybrid Fuzzy C-Means Clustering And Xgboost, Muntadher Mohammed Kareem, Rawaa I. Farhan
Adaptive Phishing Url Detection Using Hybrid Fuzzy C-Means Clustering And Xgboost, Muntadher Mohammed Kareem, Rawaa I. Farhan
Karbala International Journal of Modern Science
Phishing attacks continue to evolve in sophistication, rendering static detection methods increasingly ineffective. Existing URL-based approaches suffer from limited adaptability to emerging phishing patterns, mislabeled training data, and insufficient validation protocols. This paper proposes a hybrid phishing URL detection system that integrates Fuzzy C-Means (FCM) clustering with XGBoost classification, enhanced by a novel Micro Adaptive Feature Extractor (MAFE). The system employs a multi-stage pipeline: feature engineering generating 36 statistical and interaction features, MAFE producing 15 adaptive features through class-aware dynamic weighting, micro-pattern detection, and entropy analysis, and FCM with K=2 clusters providing soft membership features to XGBoost. A two-pass confidence-based …
Implementation Of A Cognitive Aide To Guide The Use Of Non-Invasive Hemodynamic Monitoring For Goal-Directed Fluid Therapy During Cesarean Deliveries, Ashley George, Ashley Walbert
Implementation Of A Cognitive Aide To Guide The Use Of Non-Invasive Hemodynamic Monitoring For Goal-Directed Fluid Therapy During Cesarean Deliveries, Ashley George, Ashley Walbert
Doctor of Nurse Anesthesia Practice (DNAP) Manuscripts
Postpartum hemorrhage (PPH) remains a leading cause of maternal morbidity and mortality, with delayed recognition contributing to adverse outcomes during cesarean delivery. In cesarean deliveries, traditional intermittent non-invasive blood pressure monitoring may not detect early hemodynamic instability, creating a need for more structured interpretation of continuous hemodynamic data. This Doctor of Nurse Anesthesia Practice quality improvement project implemented a cognitive aid to support anesthesia providers using the Edwards EV1000/ClearSight platform during goal-directed fluid therapy. A pre–post implementation design using provider surveys evaluated feasibility, usability, confidence, and perceived impact. By organizing continuous values such as stroke volume, cardiac output, and systemic …
A Staff Nurse-Led Clinical Instructional Competency Program To Improve Clinical Judgement In Undergraduate Nursing Students: A Quality Improvement Initiative, Shana Skeffrey
Doctor of Nursing Practice (DNP) Manuscripts
There is increasing concern that new graduate nurses are leaving bedside roles early in favor of less stressful positions due to rising patient acuity and heightened organizational expectations, increasing the effects of the nursing shortage (McClosky et al., 2022; AACN, 2024). A standardized clinical experience, combined with fair and consistent access to skill application in the hospital setting can support a collaborative approach for undergraduate nursing students. This quality improvement project is aimed to implement a Staff Nurse-Led Clinical Instructional Competency Program that will provide a structured opportunity for clinical instructors to help fill the gap in preparing undergraduate nurses …
Feasibility And Acceptability Of A Home-Health Aide-Delivered Loneliness Reduction Program In A Small Home Care Agency: The Caring Connections Quality Improvement Project, Tontalayia L. Robinson
Feasibility And Acceptability Of A Home-Health Aide-Delivered Loneliness Reduction Program In A Small Home Care Agency: The Caring Connections Quality Improvement Project, Tontalayia L. Robinson
Doctor of Nursing Practice (DNP) Manuscripts
Loneliness is a significant public health concern that adversely affects mental, cognitive, and physical health, with consequences comparable to smoking 15 cigarettes per day. Home care recipients experience loneliness at rates of 15.9% to 24.2%, yet home-health aides (HHAs), who often have the most consistent contact with homebound clients, lack structured tools for recognizing and responding to loneliness. This gap highlights the need for practical, evidence-based strategies that can be integrated into routine home care practice. The purpose of this Doctor of Nursing Practice quality improvement project was to evaluate the feasibility, acceptability, and appropriateness of a home-health aide–delivered loneliness …
A Quality Improvement Initiative Utilizing Help To Reduce Delirium, Improve Patient Outcomes, And Provide Age Friendly Care For Patients 65 Years Of Age Or Older With Modifiable Delirium Risk Factors., Maggie Blake
Doctor of Nursing Practice (DNP) Manuscripts
Background: Delirium, an acute change in cognition, occurs in 21% of hospitalized patients and is linked to increased length of stay, readmissions, and increased mortality (Shen et al., 2024). In older adults, delirium prevalence increases and is linked to poor outcomes that inhibit patients' health care goals (Shen et al., 2024). Despite the well-published harms of delirium and standardized prevention measures, delirium prevention is not prioritized. Methods: HELP, originally the Hospital Elder Life Program, now preferred to be known as HELP, is a standardized delirium prevention model specifically designed to address the unique needs of hospitalized older adult patients. HELP …
Improving Chlamydia Testing For Females Through Universal Screening In Outpatient Pediatric Primary Care: An Adolescent Quality Improvement Initiative, Christina Howard
Improving Chlamydia Testing For Females Through Universal Screening In Outpatient Pediatric Primary Care: An Adolescent Quality Improvement Initiative, Christina Howard
Doctor of Nursing Practice (DNP) Manuscripts
Chlamydia is the most common sexually transmitted infection in the United States in adolescents and young adults (Dutra & Lazenby, 2023). Per Smith, Reirden, and Nyquist (2022), adolescents and young adults between the ages of 15 and 24 account for more than 60% of new chlamydia infections each year. Testing for chlamydia is not standardized, and it is estimated that only 50% of those who qualify receive a yearly screening American Sexual Health Association. (2021). If outpatient testing and treatment is not improved these asymptomatic cases will be missed, infections in general will increase, and reinfections may occur leading to …
Enhancing New Graduate Nurse Confidence And Patient Safety Through Clinical Development Coach Integration, Megan T. Kramer
Enhancing New Graduate Nurse Confidence And Patient Safety Through Clinical Development Coach Integration, Megan T. Kramer
Doctor of Nursing Practice (DNP) Manuscripts
The transition from student to professional nurse is a critical developmental stage often marked by heightened stress, emotional exhaustion, and uncertainty in clinical judgment. These challenges frequently contribute to lower confidence levels, increased anxiety, and higher risks for patient safety events among new graduate nurses. This program evaluation project aims to assess the effectiveness of integrating a Clinical Development Coach (CDC) role to enhance new graduate nurse’s confidence, comfort, and overall competence while reducing patient safety incidents on a trauma/surgical inpatient unit in a medical center on the East coast. The CDC role is a structured mentorship and resource position, …
Implementation Of A Deteriorating Patient Simulation For New Graduate Nurses To Improve Clinical Judgment: A Quality Improvement Project, Kasey Mundell
Doctor of Nursing Practice (DNP) Manuscripts
New graduate nurses (NGNs) often have trouble recognizing and responding to patient deterioration because of limited clinical judgment and confidence during the transition to practice. This quality improvement project evaluated the implementation of a high-fidelity deteriorating patient simulation within a new graduate nurse orientation program at a Level I trauma center. Guided by the Plan-Do-Study-Act framework and the International Nursing Association for Clinical Simulation and Learning (INACSL) Standards of Best Practice, the simulation focused on the assessment and management of a patient experiencing pulmonary embolism. Eight NGNs participated in the simulation and completed the Attitudes Toward Recognizing Early and Noticeable …
Evaluating The Implementation And Progress Of A Bereavement Care Program In An Acute Care Adult Hospital, Nancy Abraham
Evaluating The Implementation And Progress Of A Bereavement Care Program In An Acute Care Adult Hospital, Nancy Abraham
Doctor of Nursing Practice (DNP) Manuscripts
Bereavement care is a significant component of patient and family centered care; however, it remains inconsistently addressed in acute adult hospital settings. Families of patients who die in hospitals frequently experience grief, anxiety, and emotional distress, which may be exacerbated by fragmented or inadequate bereavement support (Kustanti et al., 2021). Evidence supports the use of structured, interdisciplinary approaches to bereavement care to ensure timely, consistent, and compassionate support for families. To address this gap, a Bereavement Committee was established at a Level I trauma center in eastern Pennsylvania to implement a standardized Bereavement Care Program aimed at improving bereavement practices …
From Novice To Competent: Enhancing Orientation And Readiness For Post-Anesthesia Care Nurses, Gerri Y. Young
From Novice To Competent: Enhancing Orientation And Readiness For Post-Anesthesia Care Nurses, Gerri Y. Young
Doctor of Nursing Practice (DNP) Manuscripts
Post-anesthesia care unit (PACU) nurses are responsible for managing complex postoperative patients requiring advanced clinical judgment, airway management, hemodynamic monitoring, and rapid recognition of complications. Many nurses transition into the PACU without formal perianesthesia education, resulting in variability in orientation practices, competency validation, and preparedness for independent practice. At a military treatment facility (MTF) in Mississippi, 78% of newly assigned PACU nurses had only one to two years of medical-surgical experience, and a standardized orientation program was not available.
This quality improvement project aimed to implement and evaluate a standardized, evidence-based PACU orientation program designed to improve nurse knowledge, confidence, …
Maternal Microchimerism As A Mechanism Of Developmental Origins Of Health And Disease, Amy M. Boddy, Kristine J. Chua
Maternal Microchimerism As A Mechanism Of Developmental Origins Of Health And Disease, Amy M. Boddy, Kristine J. Chua
Human Biology Open Access Pre-Prints
The in utero environment is now widely recognized as a critical determinant of health across the entire lifespan. The developmental origins of health and disease (DOHaD) framework has established that prenatal exposures, including maternal stress, infection, nutrition, and environmental toxins, can impact fetal development in profound ways associated with disease risk from infancy to old age. Yet a fundamental aspect of pregnancy, the bidirectional exchange of maternal and fetal cells, DNA, and other biological material, a phenomenon known as microchimerism, has received little attention in this context. Maternal cells and genomic material transfer to the developing fetus early in utero …