Digital Commons Network^™

Survodutide For Treatment Of Obesity: Baseline Characteristics Of Participants In A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial (Synchronize™-1), Carel W Le Roux, Sean Wharton, Biykem Bozkurt, Elke Platz, Gabriele Bleckert, Samina Ajaz Hussain, Martina Brueckmann, Elena Startseva, Isabel M Kloer, Lee M Kaplan

Faculty, Staff and Students Publications

Aims: Survodutide, a novel glucagon receptor and glucagon-like peptide-1 (GLP-1) receptor dual agonist, elicited significant weight loss in a phase 2 trial in individuals with obesity without type 2 diabetes (T2D). Two multinational phase 3 trials are investigating survodutide for obesity management in individuals with or without T2D. We report the baseline characteristics of participants in the SYNCHRONIZE-1 trial in adults with obesity without T2D (ClinicalTrials.gov: NCT06066515).

Materials and methods: Participants aged ≥18 years with BMI ≥30 or ≥27 kg/m2 with ≥1 obesity complication without T2D were randomized 1:1:1 to double-blind, once-weekly, subcutaneous injections of survodutide (up-titrated to 3.6 …

Students Can't Access Education Without Being There: A Systematic Look Into One School's Approach To Improve Access, Shawn A. Bernard

Educational Leadership Professional Doctorate Dissertations

This improvement science dissertation focused on understanding and reducing the frequency of out-of-classroom removal of students exhibiting challenging behavior in one elementary school. Classroom removals result in lost instruction and reduced access to the general education environment. Baseline data indicated an average of 27.8 classroom removals per day, reflecting a systemic issue impacting both student outcomes and staff capacity. The goal was to reduce classroom removals to fewer than 10 per day by June 2026. The leadership team conducted a root cause analysis to inform a theory of improvement grounded in positive behavioral interventions and supports (PBIS). The team selected …

Organizational Causes Of Chronic Absenteeism: Unpacking The Conditions For Learning To Increase Regular Attendance, Melissa Glover

Educational Leadership Professional Doctorate Dissertations

This study employed an improvement science methodology, using plan-do-study-act (PDSA) cycles of improvement, to address the persistent problem of chronic absenteeism within the Gateway School District, where annual absentee rates hovered around 45% and were historically 10% higher for students with disabilities compared to their nondisabled peers. The leadership team engaged in a thorough review of parent and student perceptions of school and aligned findings with Chang’s (2019) conditions for learning framework to pinpoint actionable areas for growth. These findings were then organized into a theory of action using a driver diagram approach. This foundational work led to the identification …

Reproductive Rights On Campus, Janet Levit

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.

Binding The Visual Experience Of Law, Nicholas Mignanelli

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.

Mindful Diagnostics In Culture-Negative Endocarditis: Early Noninvasive Diagnosis Of Tropheryma Whipplei By Plasma Microbial Cell-Free Dna, Ashita Jain, Sarwat Khalil, Muhammad R Sohail, Laura C Lelenwa, Enrique Garcia-Sayan, Kenneth K Liao, Ahmed Hamdi, Todd Lasco, Mayar Al Mohajer

Faculty, Staff and Students Publications

Tropheryma whipplei was identified by plasma microbial cell-free DNA sequencing within 4 days in severe culture-negative endocarditis after antibiotics had already been started. The result supported earlier diagnostic clarification and antimicrobial de-escalation before valve pathology was available, illustrating a practical diagnostic-stewardship role for noninvasive sequencing in high-acuity endocarditis.

Disrupted Intrathalamic And Thalamocortical Structural Covariance Networks In Posttraumatic Stress Disorder, Nick Steele, Ahmed Hussain, Delin Sun, C Lexi Baird, Courtney Russell, Neda Jahanshad, Lauren E Salminen, Miranda Olff, Jessie L Frijling, Dick J Veltman, Saskia B J Koch, Laura Nawijn, Mirjam Van Zuiden, Li Wang, Ye Zhu, Gen Li, Dan J Stein, Jonathan Ipser, Sheri Koopowitz, Yuval Neria, Xi Zhu, Orren Ravid, Sigal Zilcha-Mano, Amit Lazarov, Benjamin Suarez-Jimenez, Ashley A Huggins, Jennifer Stevens, Kerry Ressler, Tanja Jovanovic, Sanne J H Van Rooij, Negar Fani, Emily L Dennis, David F Tate, David X Cifu, William C Walker, Elisabeth A Wilde, Ivan Rektor, Pavel Říha, Milissa L Kaufman, Lauren A M Lebois, Justin T Baker, Anthony King, Israel Liberzon, Mike Angstadt, Nicholas D Davenport, Seth G Disner, Scott R Sponheim, Thomas Straube, David Hofmann, Guang Ming Lu, Rongfeng Qi, Amit Etkin, Adi Maron-Katz, Xin Wang, Austin Kunch, Hong Xie, Yann Quidé, Wissam El-Hage, Shmuel Lissek, Hannah Berg, Steven E Bruce, Josh Cisler, Marisa Ross, Ryan Herringa, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine Larson, Terri A Deroon-Cassini, Carissa W Tomas, Jacklynn M Fitzgerald, Brandee Feola, Jennifer U Blackford, Bunmi O Olatunji, Geoffrey May, Steven M Nelson, Evan M Gordon, Chadi G Abdallah, Ruth Lanius, Maria Densmore, Jean Théberge, Richard W J Neufeld, Paul M Thompson, Rajendra A Morey

Faculty, Staff and Students Publications

The thalamus is a heterogeneous structure crucial for corticocortical communication, affective–perceptual integration, motor preparation, and memory-related functions. Posttraumatic stress disorder (PTSD) is characterized by various symptoms that likely relate to thalamic functions. Group-level and individual differential structural covariance (SC) analyses were conducted on intrathalamic, thalamocortical, and thalamosubcortical volumetric networks by segmenting structural MRI data from 2,784 subjects (PTSD n = 1,306; controls n = 1,478) into 25 thalamic nuclei per hemisphere. We found that PTSD was associated with stronger intrathalamic and thalamocortical network strength and stronger SC between the limbic thalamus and the somatomotor and auditory thalamus. PTSD severity was …

A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)

Faculty, Staff and Students Publications

Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, the Tuberculosis Network European Trials group (TBnet; www.tbnet.eu) is one of the leading research networks in Europe. In this review, we summarize the main advances in TB and NTM that occurred in 2025.

Methods: We conducted a non-systematic review of articles published in 2025, with a strong emphasis on research with current or potential impact on clinical practice. We also selected the most impactful papers regarding the management of adult …

The All Of Us Evenings With Genetics Research Program, Stacy M Lloyd, Jasmine Baker, Carolina Jorgez, Julie Coleman, Laterrica Williams, April Adams, Ashley Butler, Elizabeth Atkinson, Shamika Ketkar, Steven Scherer, Kim Worley, Susan Fernbach, Keasia Daniels, Latanya Hammonds-Odie, Laura Rosales, Brendan Lee, Debra Murray

Faculty, Staff and Students Publications

The All of Us Evenings with Genetics (All of Us EwG) Research Program, funded in part by the National Institute of Health’s All of Us Research Program, engages researchers to utilize the All of Us Researcher Workbench to advance precision medicine. The All of Us EwG program has two core aims: (1) address barriers to research productivity for minorities, disadvantaged, and persons with disabilities aspiring to enter STEM fields; and (2) promote the use of the All of Us Researcher Workbench to develop research focused on health equity. To achieve these goals, the program implements three key activities: (1) …

Can You Hear Me Now?, Daniel Gonzalez, Amanda Moore

Faculty Publications

No abstract provided.

The Torch: 2025-2026 In Review, Suffolk University Honors Program

Torch Newsletter

No abstract provided.

From Measuring Clicks To Inclusion: Coverage Of Digital Adolescent Sexual And Reproductive Health Programs, Miriam Temin, Christabel Gero

Adolescents and Young People

Digital platforms have become popular tools to address adolescents’ sexual and reproductive health and rights (ASRHR) in low- and middle-income countries. Digital programming has the potential to bridge the SRHR information gap, especially for adolescents who face SRHR risks. Given what is known about the digital divide, it is essential to understand who digital ASRHR programming reaches, who is excluded, and how coverage aligns with risk. This brief summarizes an exploration that aims to stimulate interest and seed research on issues of coverage of digital programming for adolescents and its public health importance.

Rise, Lead, Thrive: A Young Feminist's Path To Leadership, Population Council Kenya, Nawiri Project

Adolescents and Young People

Information Education and Communication graphic created for the Young Feminist Organizing (YFO) project.

Evaluating Datasets And Models For Offensive Language Identification, Skye Deson Morgan

Theses

Social media platforms enable people to easily communicate with one another, share ideas and express their opinions. Unfortunately, the anonymity provided by platforms such as Twitter and Facebook is more than enough to foster the spread of harmful content. Government agencies, as well as technology companies, are actively working towards finding better means of curbing offensive and objectionable content in social media and contributing to a more welcoming online environment. In this study, I first present a critical literature review on offensive language identification, exploring offensive language datasets and computational models using both machine learning and deep learning. Next, I …

Supporting Latine Older Adults’ Nutrition And Physical Health Goals In Counseling, Zachary P. Mcniece, Jacqueline J. Bergman

Faculty Research, Scholarly, and Creative Activity

Latine older adults face disproportionate risk of chronic nutrition-related conditions and food insecurity, which can exacerbate or contribute to the development of mental health-related concerns. Cultural stigma toward mental illness can result in Latine clients, especially older adults, somatizing symptoms and focusing on physical health goals in counseling. Despite these intersecting needs, counselors often overlook clients’ physical health goals due to limited training and the assumption that medical providers alone should address them. This article advocates integrating basic, culturally responsive nutrition information into counseling practice to support client well-being while staying within the scope of practice. We offer practical recommendations …

The Energy Change Of Graphs Under Some Edges Deletions, Huan Lei Shi, Wen Huan Wang, Wasin So

Faculty Research, Scholarly, and Creative Activity

The energy ε(G) of a graph G is the sum of the absolute values of all the eigenvalues of its adjacency matrix. Gutman (2001) pointed out a problem to characterize the graph G and the edge e of G such that ε(G − e) ⩽ ε(G). Tang et al. (2023) gave a sufficient condition for ε(G − e) ⩽ ε(G), where e is not necessarily a cut-edge set or a cut edge. We deduce here a stronger conclusion than the results obtained by Tang et al. (2023). Our findings cover some known conclusions, such as the results obtained by Gutman …

Engage & Empower Vol. 2, Elhanan Marvit

Open Touro Created

2026

Engage & Empower, Volume 2 is the second installment in the “Engage & Empower” OER series by Elhanan Marvit LCSW. It serves as the logical next step following Volume 1 (Spring 2025). While the first volume introduced foundational concepts in social work practice, ethics, and generalist skills This volume guides students and readers deeper into the applied, interpersonal, and reflective dimensions of becoming a competent practitioner.

Students begin their reading journey as they strengthen their understanding of professional competence. They achieve this by learning how to navigate field placements, engage in supervision, manage boundaries, and integrate feedback. The text …

Surface Marker Identification To Capture Live Circulating Tumor Cells In Metastatic Triple-Negative Breast Cancer, Bree M Lege, Khushali J Patel, Brendan Panici, Ping Gong, Michael T Lewis, Matthew J Ellis, Chonghui Cheng

Faculty, Staff and Students Publications

Metastatic triple-negative breast cancer (TNBC) is highly aggressive and lacks targeted therapies. Circulating tumor cells (CTC) are invaluable for monitoring metastatic tumor progression and treatment response but are difficult to capture because of their rarity and heterogeneity. Surface-based staining for live CTCs is essential to preserve RNA quality in single cells, but current markers tend to perform poorly on more mesenchymal tumor cells such as TNBCs. To enhance live TNBC CTC detection, we developed a workflow for live CTC capture and single-cell RNA sequencing (scRNA-seq). Using a mouse model of metastatic TNBC, we identified four new CTC surface markers, AHNAK2, …

Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso

Faculty, Staff and Students Publications

Wastewater-based epidemiology (WBE) is the analysis of wastewater to detect pathogen levels or activity for public health awareness or action. Pioneered in the 1940s, WBE underwent a resurgence during the COVID-19 pandemic, providing important information about number of cases, outbreaks, and seasonal impact. With advancements in detection technologies and growing interest in environmental surveillance, WBE is poised to become a standard practice in public health monitoring. Here, we provide an overview of the current state of the art of pathogen WBE, including methods of molecular detection, analysis of wastewater data, real-world applications and programs, public health interventions, and benefits and …

Helicobacter Pylori And Cancer: What's The Link?, Elettra Merola, Giovanni Mario Pes, David Yates Graham, Maria Pina Dore

Faculty, Staff and Students Publications

Helicobacter pylori (H. pylori) is a human bacterial pathogen that causes one of the most common chronic bacterial infections worldwide. The microorganism has been classified by the International Agency for Research on Cancer as a Group I carcinogen. While the etiological link to gastric cancer is well established, the precise molecular and cellular mechanisms driving this transformation are highly complex and incompletely understood. Fundamentally, the infection results from the chronic presence of acute on chronic gastric mucosal inflammation. H. pylori pathogenicity is increased by bacterial virulence factors including the cytotoxin-associated gene A (CagA) and Vacuolating cytotoxin A (VacA) …

The Development And Pilot Evaluation Of An Out-Of-Hospital Immersive Birthing Simulation Training Application For Paramedics And Ambulance Officers Using Virtual-Reality Technology, Michella Hill

Theses: Doctorates and Masters

Out-of-hospital births (OOHBs) are births which occur outside a hospital setting. This includes planned home births attended by midwives, or unplanned OOHBs where the intention was to birth in a hospital or maternity centre, however, occurs in an unintended location. Prehospital clinicians, inclusive of registered paramedics and volunteer ambulance officers (VAOs) infrequently attend OOHBs, as most births occur in maternity wards as anticipated. OOHBs comprises < 1% of emergency ambulance requests and requires specialised skills for prehospital clinicians to competently manage birthing and potential complications. As exposure to birthing is so rare, these specialised skills and knowledge are underutilised and subject to rapid decay. Compounding the problem, obstetrics is infrequently taught across undergraduate education, in-service training, or within individual clinician’s continuing professional development. Placements shadowing midwives are scarce due to nursing and medical students receiving priority. Previous research regarding OOHBs is limited, nonetheless suggests prehospital clinicians are underprepared to manage an OOHB, which has serious patient safety implications. The present research sought to explore prehospital clinicians’ preparedness and confidence in managing OOHBs. It also investigates whether a digital training solution such as virtual reality (VR) simulation may reduce the theory-practice gap and assist in competency retention.

Publication one provides a comprehensive methodology outline which is applied to Study One; a scoping review of prehospital clinician and birth parent experiences with OOHBs. Risk factors, complications and interventions provided by prehospital clinicians, as …

Getting Ready Right: The Impact And Influence Of The University Appointed Supervisor, Madlen Griffiths

Theses: Doctorates and Masters

Initial Teacher Education professional experience is a valued component of teacher education courses, where preservice teachers can practise applying what they have learned at university in classroom settings. Key to these experiences are supervisors, who are employed by the university and support these aspiring teachers during their professional experiences. This supervisory role is complex, underrated, under-theorised and under researched. Consequently, this research sought to address this shortfall through an investigation into the perspectives of two of the major stakeholders in these experiences: the preservice teachers and the supervisors.

Adopting a social constructivist methodology, this research examined the stakeholders’ perceptions of …

Injectable Borate/Borosilicate Bioactive Glass Systems For The Regeneration Of Hard Tissue – A Critical Review Of The Literature, S. Sina Mohammadi, Sunjeev S. Phull, Ryan J. Gilbert, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bone defects caused by trauma, infection, or tumor resection remain difficult to treat because successful repair requires both structural restoration and control of the local pathological microenvironment. Osteolysis, defined as pathological bone resorption, is central to many of these conditions and is commonly driven by excessive osteoclast activity. Clinically translated injectable products such as NovaBone® Putty demonstrate the value of moldable bioactiveglass grafts for defect filling; however, conventional silicate bioactive glasses are permanent and provide limited therapeutic ion release. This limitation has motivated the development of injectable borate bioactive glass (B-BGs) and injectable borosilicate bioactive glass (BS-BG) systems as more …

Stem Identities Of Iowa State University's Biological And Biomanufacturing Systems Technology Students, Levi Nettleton

Dissertations and Theses @ UNI

STEM identity plays a crucial role in students' pursuit and persistence into the STEM field. Iowa State University's Biological and Biomanufacturing Systems Technology (BBST) undergraduate program, developed in alignment with the goals of Chemurgy 2.0, prepares students for careers in the growing STEM workforce. The purpose of this study is to examine how participation in the Biological and Biomanufacturing Systems Technology program influences undergraduate students' STEM identity and how students within the program perceive themselves within the scope of STEM. Specifically, the study investigates students' perceptions of their STEM identity across the four components of STEM identity: recognition, performance and …

Fundamentals Of Speech, Steelman Library, David Yates

Syllabus Repository

No abstract provided.

Fluid Dynamics Of A Microfluidic Micromixer–Micropump Driven By Adjacent Micro Synthetic Jets, Delara Soltani, Tim Persoons, Sajad Alimohammadi

Research Outputs: 2025-Present

Efficient mixing at the microscale remains a significant challenge in microfluidic systems due to the dominance of laminar flow and the consequent limitation of convective transport. Synthetic jets, generated by the oscillatory motion of a diaphragm within a cavity, produce a zero net mass flux while imparting periodic momentum to the surrounding fluid, thereby enabling localised flow perturbation and vortex generation that can substantially enhance mixing and mass transfer in microchannels. In this study, a pair of adjacent micro synthetic jets (AMSJs) is positioned perpendicularly to a microchannel to investigate their potential as a novel micropump-mixer. The vectoring effect of …

Instruction Request: Podcasting In An Academic Library To Connect Library Instruction With Campus And Community, Lauren Odom, Beryl White-Bing

Library Faculty Presentations & Publications

The Instruction Request podcast is co-hosted by two librarians at the University of North Florida: Beryl White-Bing, Virtual Learning Librarian, and Lauren Odom, Instruction Librarian. Both of us serve in the Instruction Unit at the Thomas G. Carpenter Library. In an era where digital content is essential for engagement, we sought a way to modernize our library outreach without compromising our instructional mission. Podcasting emerged as the perfect format for highlighting educational content while being accessible and scalable.

On The Surface: The Mural Of Shireen Abu Akleh As Space For Encounter, Saja Abd El Hai

Dissertations and Theses @ UNI

This thesis examines a mural of Palestinian journalist Shireen Abu Akleh in the city of Baqa al-Gharbiya as a site of political encounter. Rather than approaching the mural solely as a commemorative image, the study analyzes how it generated a series of interactions through acts of creation, defacement, restoration, performance, and digital circulation. Drawing on scholarship in visual culture, graffiti studies, and political theory, I argue that the mural operates as a gendered space of political encounter through which grief, resistance, and national identity are negotiated in public space. Methodologically, the project combines visual and contextual analysis with rhetorical criticism, …

Two Cheers For Cox V. Sony, James Gibson

Law Faculty Publications

There’s a lot to dislike about the Supreme Court’s opinion in Cox Communications, Inc. v. Sony Music Entertainment. It mischaracterizes, oversimplifies, and ignores precedent. It fails to engage with important arguments. It mangles the meaning of “intent.” And it introduces uncertainty into the workings of secondary liability across other intellectual property regimes.

For these reasons, the decision doesn’t deserve three cheers. But it deserves two. Because in two important ways, the Supreme Court has succeeded. First, the opinion fixes some misguided appellate court holdings by articulating a relatively workable standard for future copyright cases involving secondary liability. Second, despite …

Dismantling The Whiteness Of Legal Education, Doron Samuel-Siegel

Law Faculty Publications

Whiteness is not merely a racial description. Whiteness operates as allegiance to structural racism. The quiet engine of racial hierarchy, whiteness pervades and shapes traditional legal education, rendering legal pedagogy a structurally racist enterprise. Legal education not only reproduces the racism embedded in the law and legal profession, but also obscures the ways legal doctrine, professional norms, and pedagogical practices normalize, protect, and make invisible the advantages that accrue to whiteness itself. In doing so, itproduces lawyers ill-equipped to dismantle structural injustice.

This Article breaks new ground in the scholarship on legal pedagogy by defining whiteness as it operates within …