Digital Commons Network^™

Dupilumab For Patients With Allergic Fungal Rhinosinusitis, Amber U. Luong, Joshua M. Levy, Sarah K. Wise, Joseph K. Han, Mamoru Yoshikawa, Luo Zhang, Rodney Schlosser, Prerna Ranganathan, Paula Dakin, Jennifer Maloney, George D. Yancopoulos, Andrew P. Fontenot, Neelam A. Phadke, Lacey R. Robinson

Department of Otolaryngology (ENT) Faculty Publications

Background

Allergic fungal rhinosinusitis (AFRS) is a severe subtype of chronic rhinosinusitis characterized by fungal hypersensitivity and accentuated type 2 inflammation. Dupilumab-a fully human monoclonal antibody blocking interleukin-4/13, approved for type 2 inflammatory diseases, including chronic rhinosinusitis with nasal polyps-may benefit patients with AFRS.

Objective

We sought to understand the effect of dupilumab in AFRS

Methods

In this phase 3 trial, patients with AFRS aged ≥6 years were randomized to dupilumab or matched placebo for 52 weeks. The primary end point was Lund-Mackay computed tomography (LMK-CT) score, quantifying sinus opacification, at 52 weeks. Secondary end points were multiplicity-controlled and hierarchically …

Advances In Active And Passive Integrated Photonic Devices On Thin-Film Lithium Niobate, Pooja S. Kulkarni

Graduate Studies Theses and Dissertations 2026

Thin-film lithium niobate (TFLN) has emerged as a powerful platform for integrated photonics, combining the exceptional electro-optic, nonlinear, and optical properties of bulk lithium niobate with the scalability and compactness of planar nanophotonic technologies. Building on these principles, advanced device architectures such as adiabatic dichroic filters have demonstrated exceptional spectral performance spanning over two octaves of bandwidth on the TFLN platform. Beyond reciprocal devices, it also offers promising pathways toward integrated nonreciprocal components. By leveraging broadband filtering structures and advanced nonlinear photonic design strategies, compact and monolithic optical isolators can be envisioned without relying on traditional magneto-optic materials. In the …

A Complex Systems Integration Analysis Approach, Tamia Neal

Theses

It has been said that if the building blocks of a system were designed and implemented correctly, then their subsequent integration would be straightforward. The complex systems integration analysis approach presented in this thesis provides the mechanisms to construct those blocks. A spectral clustering algorithm is used to cluster elements into modules, and the normalized integrative complexity metric is used to evaluate the portion of structural complexity that can be attributed to integrating a system from its modules. Together, the algorithm and metric identify which aggregates of system elements reduce the complexity of the integration effort. The proposed integration analysis …

Evaluating The Operational Performance Of Diverging Diamond Interchanges Under High Heavy Vehicle Traffic Using Synchro Traffic Simulation Software, Hannah Duke

Theses

Diverging Diamond Interchanges (DDIs) are increasingly used to improve traffic flow and safety, particularly where left-turn volumes are high. However, their operational performance under high heavy vehicle percentages has not yet been evaluated. This thesis investigates the impact of varying HV percentages and traffic volumes at a sample DDI location. Traffic simulation using Synchro software was used to model the DDI under scenarios with varying heavy vehicle percentages and varying volumes. This approach allowed evaluation of traffic growth and increasing heavy vehicle presence on DDI performance, capturing realistic operational conditions for freight-heavy corridors. Key performance measures included average control delay, …

Characterization Of Krypton Ion Sputtering Of Spacecraft Materials Using Electric Propulsion, Ethan Cummins

Theses

In the field of electric propulsion (EP), xenon is the most commonly used gas for ionization. However, krypton has been identified as a potential substitute due to its high specific impulse and low cost compared to xenon. Therefore, there is a desire to understand the effects of using krypton. In EP, sputtering of spacecraft materials downstream of the ion engines have proven to be an issue during long duration missions. This research observes how krypton ions sputter a variety of spacecraft materials (anodized aluminum, glass, BN ceramic, and Kapton). The experiments in this study subject materials to different sputtering variables …

Front Matter

Comparative Civilizations Review

No abstract provided.

Book Review: All The Noise At Once, Shalece Garff

The Utah English Journal

All the Noise at Once depicts the life of two incredibly close brothers. The eldest is the star quarterback and is being headhunted by universities across the nation (Brandon), while the other is living with autism and difficulties that come with it (Aiden). Unfortunately, many of the activities that he and his brother are involved in (school and football) are almost always crowded and filled with commotion, which sometimes leads Aiden to experience meltdowns when he is overstimulated with touch and noise. Being seen as different puts him on the outs with the other football players, who regard him as …

The Future Of The English Class Essay: Reimagining Multimodal Composition In The Chatgpt Era, Taylor Rose-Dougherty, Christy Goldsmith

The Utah English Journal

As English teacher educators, we are on the frontlines of navigating the technological elephant in the 2025 writing classroom: Generative Artificial Intelligence (GenAI) technologies like ChatGPT, Claude, and Gemini that can produce pages of text in mere seconds. English teachers’ philosophies on GenAI are as diverse as their preferred novels or their favorite poets. But, as the two dozen publications in major English education journals1 in the past two years suggest, what is at stake is not the end of high school English (Herman, 2022), but the opportunity to give it a makeover (Herman, 2023) by reimagining what writing experiences …

Incorporating Texts With People With Disabilities Amidst Scripted Curricula, Kayleigh Kearsley

The Utah English Journal

As I prepare for student teaching this spring, the topic on my and my peers’ minds is scripted curriculum. For emerging teachers, it can be intimidating to determine how to balance the best teaching practices developed in coursework with scripted curriculum, while simultaneously fostering an authentic learning community within my classroom walls. With the rise of scripted curriculum across the state and nation (Kang, 2016), this is becoming an increasingly complex situation to navigate. These curricular resources affect teacher choice, requiring educators to become that much more intentional with the choices they make. An important way to ensure we are …

Teaching Students To Write For The Future By Writing For The Present, Amber Jensen, Meridith Reed

The Utah English Journal

“When you get to eighth grade, you’ll need to know how to write a topic sentence.”

“The five-paragraph essay will prepare you to write in high school.”

“College professors expect you to accurately cite your sources in MLA format.”

“When you graduate from college, you need to be able to write a professional email.”

Perhaps you heard messages like these from your writing teachers as you moved through middle school, high school, college, and into your careers. We certainly did. And perhaps, like we have, you have been a writing teacher in a middle school, high school, or college classroom …

The Role Of Physicians In Society: Perspectives From First-Year Mbbs Aspirants, Jesymol Joy, Dr Rashmi S, Amogha Shree, Dr Sunil Kumar D

Digital Journal of Clinical Medicine

Background: Physicians occupy a pivotal role in society as healers and communicators, with ethical leadership embedded in professional practice. In India, this role is evolving in response to changes in healthcare systems, increasing commercialization, and shifting societal expectations. Understanding how medical students perceive the physician’s role at the onset of medical education is vital for early professional identity development.

Objectives: To assess the motivations, perceptions, and values of first-year MBBS students regarding the societal roles, qualities, and responsibilities of physicians.

Methods: A cross-sectional study was conducted among 430 first-year MBBS students at a tertiary medical college in Mysuru, Karnataka, using …

From Controversy To Comeback: The Renewed Role Of Pralidoxime In Op Poisoning, Dr Sanaa Jain, Dr Savitha V, Dr . Shashidhara K C

Digital Journal of Clinical Medicine

Organophosphorus compounds are commonly used as pesticides in agriculture, but they are responsible for approximately one-third of suicide deaths in Asian countries.The symptoms of organophosphate (OP) poisoning vary over time and are categorized into three phases: Acute Cholinergic Crisis (minutes to 24 hours), Delayed Phase (24 hours to 2 weeks), which may include intermediate syndrome, coma, and extrapyramidal symptoms, and Late Phase (OPIDP). Treatment typically involves Atropine, Pralidoxime, and symptomatic management, including airway support and mechanical ventilation.

Staging Violence With Intentionality, Toby O'Brien

Theses and Dissertations

This thesis examines the role of the fight choreographer in the theatre while addressing the potential issues staged violence has in distracting an audience from the intended narrative of the play. Avoiding the instruction manual approach of stage combat in favor of expounding on the theory of violent entertainment, I have constructed a thesis that informs the reader of certain types of violence found in both classical and modern productions and have researched the psychological ramifications of violent spectatorship and the necessity for content acknowledgements as well as consideration for the performer’s well-being. By exploring the history of violent entertainment …

Your Left Or Mine: A Journey To Accessibility For Learning Disabilities And Neurodivergence In Stage Combat Pedagogy, Ambria Campbell

Theses and Dissertations

This thesis examines stage combat pedagogy from its inception to the present day through the lens of accessibility for learning disabilities and neurodivergence. Relevant research in education as it relates to disability is analyzed and applied to the field of stage combat pedagogy. What follows is a deconstruction and reconstruction of beginning level stage combat pedagogy to increase accessibility. These ideas are then tested and the results reflected on. This thesis focuses on college level and aged students who are the most likely demographic for beginning stage combat students. The completion of this thesis does not represent an endpoint in …

An Integrated Data-Driven Framework For Arctic Shipping: Analyzing Vessel Speed, Environmental And Ecological Factors Through Innovative Statistical Spatio-Temporal Methods, Inverse Optimization And Machine Learning, Mauli Pant

Theses and Dissertations

This dissertation develops an integrated data-driven framework to analyze vessel navigation and ecological risk in the United States Arctic from 2010 to 2019. As environmental change and maritime activity increase in the region, understanding how vessels respond to dynamic conditions and how those responses interact with marine ecosystems has become increasingly important. A central theme of this dissertation is the treatment of vessel speed as both an observed outcome and a decision variable reflecting trade- offs among operational, environmental, and ecological factors. The first chapter develops a predictive framework for vessel speed over ground (SOG) using Gaussian Process Boosting (GPBoost), …

Student Centered Approaches To Analyzing Engagement And Discourse, Kamil Hankour

Theses and Dissertations

Student engagement and participation in classroom discourse are widely recognized as powerful predictors of meaningful science learning, yet students’ own perspectives on the factors that shape their engagement and participation are currently underexamined. Prior research has established strong links between engagement, discourse and outcomes such as academic achievement (Bae & DeBusk-Lane, 2019; Fredricks et al., 2004; Sedova et al., 2019), but less is known about how students understand and interpret their experiences across individual, group-level and classroom contexts, particularly within historically marginalized populations (Cook-Sather, 2013; Schaefer et al., 2024). This three paper dissertation advances a line of inquiry integrating a …

My Mouth Is A Glutton, My Mouth Is A Lover., Cole Kamerick Eller

Theses and Dissertations

This thesis is a reflection on my relationship with jewelry. I discuss the impact of jewelry

and its materials. What are the ramifications of these objects? Politically, socially, and

spiritually. I reflect on material agency, cultural unconscious, and value systems, and

how I relate to jewelry, my love for it, and my grief for it. This work is the result of ritual

and impulse. The writing is my reflection on the results of that ritual.

Tangled Up In Blues, Clara B. Deweese

Theses and Dissertations

Martin Buber’s philosophy teaches us that when our masks fall and our armor’s unveiled, we discover humanity shared. Tangled Up in Blues unpacks the snapshot photographic practice I’ve had for years, which documents my mutually uplifting relationships, and is presented for my thesis exhibit through a painterly technique that deconstructs and reconstructs  the images onto wood panels using laser transfer. As we navigate a distracted and fragmented society made of greed and bigotry, cherishing the deep connections and shared memories brings us optimism.

Sensory Constellations, Madaline K. Gardner

Theses and Dissertations

This thesis situates neurodiversity within the field of fine arts by integrating disability studies, institutional critique, and material practices in painting and printmaking. Through visual analysis and studio-based research, the project examines how tactile engagement, color relationships, and repetitive mark-making can articulate embodied experiences of neurodivergence. It challenges dominant institutional frameworks that pathologize neurodivergent behaviors by reframing stimming as a generative and communicative practice. The resulting body of work includes both image-making and the creation of tactile objects designed to facilitate sensory interaction. The thesis proposes alternative ways of understanding artistic practice and accessibility within art institutions.

All Other Ground Is Sinking Sand, Kevin Hopkins

Theses and Dissertations

My thesis project, All Other Ground Is Sinking Sand, is a body of work that frames soft sculpture as "prophetic charm" and collaborative performance as the ceremony that charges them. In this essay, I will explore the conceptual chronology of the charms, their connection to the notion of décalage, and their potential to compel witnesses toward the immediate liberation of queer, Black individuals.

With my research centered on the necessity of shifting cultural responses to enduring racial trauma, I focus my work on deconstructing Black hypermasculine archetypes shaped by white supremacy and unpacking the tension between individual autonomy and social …

Timing And Stability Of Uav Operations In Smart City Environments: Experimental Analysis And Design Implications, Rabia Ipek Yasar

Theses and Dissertations

This thesis investigates the deployment and performance of unmanned aerial vehicles (UAVs) within the Virginia Commonwealth University Open Cyber City (OCC) testbed. The study focuses on evaluating real-time indoor positioning performance using the Crazyflie drone platform. High-precision position measurements are obtained using the Vicon motion capture system, enabling analysis of the latency between the drone’s actual position and the system-reported position. In a closed-loop control system, the time difference between the position measurement and the application of the control command is called the system delay. Both stationary (hovering) and trajectory-following experiments are conducted to evaluate system performance. Communication delays in …

Examining Mental Healthcare Underutilization Among Latino Immigrants: Healthcare Providers’ And Community Health Workers' Perspectives, Geovani Muñoz

Theses and Dissertations

Latinos continue to experience many logistical and systemic barriers to professional mental health services (Derr, 2016) despite being the second-largest racial-ethnic group in the United States (U.S.). With a community of 65 million people (U.S. Census Bureau, 2024), Latinos experience mental healthcare inequalities (Cook et al., 2019) due to structural, cultural, and systemic barriers. Although prior research has emphasized culturally responsive care as a pathway to reducing disparities (Nagy et al., 2025), much of the literature has focused on Western medical models, with limited attention to community-based perspective. Guided by the Knowledge, Attitude, and Practices (KAP) framework, the present study …

The Transition From School To Work For Students With Emotional And Behavioral Disorders: Examining The Lived Experiences Of Students In Private Day Schools, Gabrielle S. Pickover

Theses and Dissertations

This qualitative phenomenological study examined the lived experiences of young adults with Emotional and Behavioral Disorders (EBD) as they transitioned from private day school settings into sustained employment. Guided by Schlossberg’s Transition Theory, the study explored participants’ perceptions of the barriers, supports, and strategies that shaped their transition experiences. Data were collected through twelve semi-structured interviews with six participants who maintained at least one year of continuous employment following high school. Analysis revealed four primary themes: structure as a stabilizing force, resilience developed through adversity, experiential learning as a pathway to employment, and employment as identity and independence. Findings suggest …

Comorbid Psychosis In The General Population, Mariam Sankoh

Theses and Dissertations

Psychosis is a complex psychiatric phenotype characterized by substantial heterogeneity in symptom presentation, psychosis diagnosis, comorbidity patterns, and genetic architecture across diverse populations in the general population. Despite advances in psychiatric epidemiology and genomics, important gaps remain in understanding how psychosis symptoms and psychosis-related diagnoses manifest across racial and ethnic groups and how evolutionary genomic factors may contribute to disease risk and cross-ancestry genetic prediction. This dissertation, Characterizing Comorbidity in Psychosis in the General Population, integrates epidemiological, psychometric, and evolutionary genetic approaches to examine psychosis across diverse populations.

Aim 1 examined racial and ethnic differences in psychosis comorbidity patterns …

Munajat: Design As A Dialogue With The Divine, Shawky Abdalla

Theses and Dissertations

Contemporary design discourse remains grounded in functional, seemingly user-centered paradigms, often neglecting what lies beyond the tangible within a human experience. This research challenges such frameworks by positioning design as a dialogue with what exceeds the physical, moving toward the experiential, where meaning precedes and informs form. Drawing on Islamic philosophy, particularly the relationship between zahir and batin (outward form and inward meaning), the study repositions design as a medium for remembrance (dhikr) rather than mere utility.

Through a critique of modernist and postmodernist principles, the research proposes a series of objects that engage with memory, introspection, and transcendence in …

Algorhythm: Commodification Of Hobbies On Social Media Platforms, Fariha Ahmed

Theses and Dissertations

Forcing the world online, the COVID-19 pandemic appeared to turn social-media-based hobbies into income-generating cash cows. Digital creative spaces became sites of capitalist logic where hobbyists came to operate as both laborers and commodities. Profit-focused algorithms operate imperceptibly, shaping creative behavior and decision-making in ways that are difficult to recognize, and even harder to resist. This thesis asks how algorithmic participation on platforms such as Instagram conditions a hobbyist, and how that conditioning can be made legible to audiences who inhabit such platforms without always seeing them. Using autoethnography, I position myself as both researcher and subject to document the …

From Cultural Binaries To Coexistence: A Graphic Autoethnography Of Individualism And Collectivism In An International Context, Shahad Alsubaie

Theses and Dissertations

This arts-based autoethnographic study investigates individualism and collectivism, specifically through my study-abroad experience traveling from Saudi Arabia to the United States. Through arts-based reflective practice, I depicted the diasporic experience of being ontoepistemologically collectivistic while navigating a primarily individualistic society. I use the medium of a graphic memoir to illustrate and develop frameworks of confluence that embrace the two distinct cultural orientations simultaneously. This arts-based self-study not only contributes to the body of transnational scholarship but also serves as a reference for international students, researchers, and educators to use arts-based subgenres and data analysis methods to gain better insights into …

Will You Let Me In?, Irene Piazza

Theses and Dissertations

Imposed borders are everywhere: The borders created by stanchions during bureaucratic lines, the borders of a country, the borders of a page. Humans are forced to follow them. Borders are imposed structures that dictate a way to move, a way to write, a way to be confined. But what happens when those borders aren’t followed? What happens when someone decides to walk through the stanchion belt by crouching under it or sliding its buckle open? What happens if a person decides to walk outside of the paved pathway? What happens if someone crosses a border or writes beyond the page …

Contours Of Duration: Movement Authored Through Form—A Behavior Archive, Jood Senussi Elbeshti

Theses and Dissertations

Insect anatomy offers an elegant example of motion derived from structure. Inspired by insect movement, Contours of Duration employs a cam-and-follower system consisting of moving, leg-like parts, designed to engage a series of rotating cams, such that the shape of each cam’s surface activates the legs in unique ways, generating repetitive movement, and demonstrating how geometry produces distinct motion behaviors over time. Through iterative experimentation and controlled variation, trace emerges as a central methodology, whereby movement, over time, creates a distinct pattern of marks, making motion legible and reflecting how subtle changes to surface and form generate different behavioral outcomes. …

Spell Of Forty Small Failings, Erin B. Ehren

Theses and Dissertations

Spell of Forty Small Failings is a collection of images and writings that draws from an unruly range of literary forms, academic disciplines, and religious cannons in order to address the Divine—all that which exists on account of the phenomena of what it is to see and be seen: to hear and be heard: to touch and be touched: to know and be known, and through that knowing proceed beyond mediation. I wrote this thesis for me in the hopes that all along I was writing for you.