Digital Commons Network^™

Increasing Hpv Vaccination Among Early Adolescents Using A Game-Based Digital Intervention: A Randomized Controlled Trial, Angela Chia-Chen Chen, Lihong Ou, Elizabeth Reifsnider, Kimberly Arcoleo, Ashish Amresh, Michael Todd

Ellmer School of Nursing Faculty Publications

Background/Objectives: Human papillomavirus (HPV) vaccination coverage among adolescents remains below public health targets despite strong evidence of vaccine effectiveness in preventing HPV-related cancers. Digital interventions (e.g., serious games) may improve HPV vaccine uptake, but evidence for effects on vaccination behavior remains limited. Methods: This secondary analysis of a randomized controlled trial evaluated a co-designed, game-based digital intervention to increase HPV vaccine initiation among unvaccinated youth aged 11-14 years and their parents. The sample included 64 parent-adolescent dyads (33 intervention and 31 usual care dyads). The primary outcome was HPV vaccine initiation at 2-month follow-up. Results: A significantly greater proportion of …

The International Order, International Law, And The Definition Of Security, Harlan G. Cohen

Faculty Scholarship

As economic security has seemingly moved to the center of American and European foreign policy, both the United States and the European Union have broadened their interpretation of international law rules governing security, coercion, and intervention. But these interpretations are not exactly new, echoing developing state interpretations of international law that developed states had long ago seemingly rejected. How are these once moribund interpretations of security, force, and coercion being brought back to life?

This article argues that these interpretative shifts highlight the role of the international order as an interpretative mechanism within international law. Borrowing from the work of …

Transparency As A Regulatory Duty, Olivier Sylvain

Faculty Scholarship

This symposium piece offers a simple survey of transparency measures addressed to deepfakes and other related consumer harms, as well as the constitutional problems they present.

Handwriting Recognition In Vr, Dominique Mosley

EWU Masters Thesis Collection

Virtual Reality (VR) is slowly becoming more popular for more than just entertainment. VR can be found in educational, office, and even healthcare settings to help discover more intuitive ways to teach, collaborate, and treat patients. Outside of the virtual world, these environments typically rely on writing for communicating or note-taking. Currently, VR input forces users to rely on clunky on-screen keyboards which disrupts the user’s immersion and breaks the flow of natural interaction. This thesis explores the potential of VR as a learning platform by combining it with artificial intelligence (AI). It aims to develop a VR-enhanced handwriting practicing …

Extracellular Vesicles In Prostate Cancer: Current Understanding And Future Perspectives, Balaji Perumalsamy, Parthasarathy Seshacharyulu, Raghupathy Vengoji, Nicole Shonka, Benjamin A. Teply, Surinder K. Batra, Sakthivel Muniyan

Journal Articles: Biochemistry & Molecular Biology

Exosomes are nanoscale, lipid bilayer extracellular vesicles (EVs) actively secreted by cells under both physiological and pathological conditions. As key mediators of intercellular communication, exosomes carry a diverse array of molecular cargo, including nucleic acids, proteins, lipids, and metabolites, which can influence the function of recipient cells. Based on evidence from 2016–2025 across PubMed, Embase, the Cochrane Library, and clinicaltrials.org, this review consolidates current understanding of exosome biology in prostate cancer (PCa). We discuss exosome biogenesis, molecular cargo composition, and their functional roles in tumor progression, angiogenesis, immune evasion, metastasis, and therapy resistance of PCa. We emphasize the biomarker potential …

Pancreatic Cancer Detection Consortium Biomarker Bakeoff: A Phase Ii Blinded Biomarker Validation And Panel Discovery Study, Ann L. Oberg, William R. Bamlet, Grant Izmirlian, Seetharaman Balasenthil, Surinder K. Batra, Masataka Hayashi, Daniel S. Herman, Michael A. Hollingsworth, Maneesh Jain, Ann M. Killary, Brianna M. Krusen, Suyu Liu, Shounak Majumder, Gopalakrishnan Natarajan, Subrata Sen, Lynette M. Smith, Sudhir Srivastava, Brian M. Wolpin, Kenneth S. Zaret, Michael G. Goggins

Journal Articles: Biochemistry & Molecular Biology

PURPOSE: The Pancreatic Cancer Detection Consortium (PCDC) performed a blinded Early Detection Research Network-defined phase II biomarker bakeoff study of blood-based biomarker panels. The aims were to evaluate panel performance, to compare the panels' performance with that of cancer antigen 19-9 (CA19-9) alone, and to evaluate the performance of new combinations of the individual biomarkers.

EXPERIMENTAL DESIGN: Ten biomarkers representing eight biomarker panels and CA19-9 were evaluated using plasma, serum, and germline DNA from 140 stage I to IV pancreatic ductal adenocarcinoma (PDAC) cases and 140 controls from three tertiary care institutions, with controls frequency matched to cases on age …

Iv Contrast For Mri And Ct In Patients With Kidney Disease, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Early Mobility In Icu Delirium, Audra Lambert Bsn, Rn, Cierra Alexander Bsn, Rn, Desmond Otasowie Bsn, Rn, Sydney Remeis Rn, Jeanie Sy Bsn, Rn, Hope Brown Bsn, Rn, Skylar Wooster Rn

Nurse Residency Posters

Facilitator: Ashley O'Day, MSN, RN CCRN

OhioHealth Grant Medical Center

Decreasing Incidence Of Falls During Change Of Shift, Najma Ali Adn, Rn, Kwabena Barnie Adn, Rn, Laura Bishop Bsn, Rn, Shalay Dale Bsn, Rn, Alli Fields Bsn, Rn, Tia Guo Adn, Rn, Ayan Haji Adn, Rn, Halley Spears Adn, Rn, Allison Stewart Adn, Rn, Courtney Uriostegui Bsn, Rn

Nurse Residency Posters

Facilitator: Dustin Eckert, BSN, RN

OhioHealth Riverside Methodist Hospital

Chaplain Service Benefits, Gabbie Bender, Jonathan Bennett, Maria Sebastiano, Tyler Moore, Azad Robinson, Amanda Hale, Rebecca Price

Nurse Residency Posters

Facilitator: Dara Pence

OhioHealth Pickerington Methodist Hospital and OhioHealth Berger Hospital

Ticket To Ride, Dakota Jenkins Rn, Darbi Brewer Bsn, Rn, Jedidiah Miller Bsn, Rn, Mattison Comer Bsn, Rn

Nurse Residency Posters

OhioHealth Berger Hospital

From Flexibility To Friction: Intended And Unintended Consequences Of Hot-Desking In Workplaces, Cheuk Hang Au, Lin Yue, Siqi Gao, Guanglei Cheng

Research outputs 2022 to 2026

Purpose: This study aims to theorize the tensions of hot-desking. Moving beyond its surface-level effects, we explain its complex impact on employee well-being and organizational conflict.

Design/methodology/approach: Using a multi-platform netnographic approach, we analyzed unsolicited discussions from online communities to capture diverse, authentic experiences across Eastern and Western contexts.

Findings: Grounded in technology affordance and constraints theory (TACT), our central finding is that hot-desking's affordances and constraints are dynamically co-produced. The organizational affordance of space efficiency is directly experienced by employees as a constraint of spatial insecurity and resource deprivation. This core tension fuels emergent social conflicts, such as senior …

Changing Student Perspectives On Alcohol, Smoking & Vaping Through The Use Of Tetrahymena, Courtney Hausner, Douglas L. Chalker, Alexandra Forgerson, Carol E. Colaninno, Alison Brockhouse, Rachel Ruggirello

Institute for School Partnership: Research & Publications

We describe the redesign and classroom testing of an Advancing Secondary Science Education through Tetrahymena (ASSET) module addressing adolescent alcohol, smoking, and vaping. Using the 5E instructional model, the module has students investigate how alcohol, cigarette smoke extract, and vape extract affect the ciliated protozoan Tetrahymena, an accessible proxy for effects on ciliated human respiratory cells. Students analyze public health data, conduct guided and self-designed investigations, and create outreach posters communicating evidence-based risks to peers. We report on observations from two classroom implementations, describing gains in students' ability to articulate toxicology concepts, connect cellular findings to whole-body health, and express …

Clinical Data Integration: Impact On Quality Outcomes, Sora Park Choi

Yale School of Nursing Digital Theses

Clinical Data Integration: Impact on Quality Outcomes

Hospital readmissions continue to contribute substantially to poor patient outcomes and rising healthcare expenditures in the United States, with nearly 20% of Medicare beneficiaries readmitted within 30 days. Fragmented health information systems also impede care coordination and restrict providers’ capacity to deliver timely, high-quality care. This Doctor of Nursing Practice (DNP) project developed, implemented, and evaluated a provider dashboard that integrates real-time clinical and operational data to support primary care providers within a large multistate independent provider association.Guided by the Lean Six Sigma DMAIC framework, this quality improvement project was conducted with 10 …

Improving Patient-Centered Communication To Reduce Falls In A Suburban Community Hospital, Shaun Craig Dickson

Yale School of Nursing Digital Theses

Inpatient falls remain a significant and often preventable patient safety concern that cause harmand increase health delivery costs for health systems across the United States. Communication barriers between bedside clinicians and their patients are a known contributor to falls. This Doctor of Nursing Practice (DNP) quality improvement project evaluated whether a structured communication intervention could reduce falls by improving communication in a suburban community hospital. This project was implemented on a 30-bed Observation-Medical-Surgical unit. Nurses and Patient Care Technicians (PCTs) were trained in using the Plain Language, Engagement, Empathy, Empowerment and Respect (PEEER) Model of Communication to deliver individualized fall …

Increasing Adherence To Cognitive Behavioral Therapy Among Patients With Major Depressive Disorder, Tina Ho

Yale School of Nursing Digital Theses

Major depressive disorder (MDD) is a prevalent psychiatric condition that significantlyimpairs daily functioning, cognitive performance, and overall quality of life. Evidence-based interventions, including pharmacotherapy and psychotherapy, are effective in managing MDD, with cognitive behavioral therapy (CBT) recognized as one of the most empirically supported treatments (Cuijpers et al., 2016). Interventions are needed to improve adherence to CBT to reduce relapse rates by addressing barriers to engagement and supporting sustained participation in treatment. This project developed and implemented a standardized protocol to improve CBT adherence among patients with MDD newly referred for combined CBT and medication management. A new ‘barriers form’ …

Beyond Assumptions: What Students Really Think About School Wellbeing Programs, Amanda Madden

Research outputs 2022 to 2026

The study examined students’ perceptions of effective components in school-based wellbeing programs, addressing a critical gap where adolescent voices are absent. Data was gathered through a questionnaire, individual interviews, and focus groups conducted with 36 Year 12 students across three independent co-educational schools in Western Australia. Thematic analysis identified seven key components essential for effective wellbeing programming: targeted content providing respite from academic pressures, engaging and relatable presenters, strategic timing, developmental appropriateness, meaningful measurement, genuine teacher engagement, and authentic incorporation of student voice. Students valued practical, non-academic content and expressed scepticisms about teacher-delivered programs. Timing emerged as a previously underexplored …

Strengthening Ocean Literacy: Marine Science Education And Training To Ensure Australia's Blue Future, Prue Francis, Rachel Kelly, Louise Swanson, Tanveer M. Adyel, Benjamin Arthur, Kirsten Benkendorff, Melanie J. Bishop, Helen Bostock, Marnie L. Campbell, Emma Church, Corrine Condie, Vaibhavi Dwivedi, Michelle Dyer, Matthew England, Liam Fullbrook, Charlie Huveneers, Malcolm Johnson, Brianna Le Busque, Rebecca R. Mcintosh, Amelie Meyer, Benjamin Mos, Jana Mrazova, Allyson O'Brien, Gretta T. Pecl, Amandine Schaeffer, Rebecca J. Shellock, Grant A. Smith, Scott Smithers, Ana Vila-Concejo, Graham Wood

Research outputs 2022 to 2026

This white paper sets out a national vision for advancing ocean literacy in Australia and outlines the role of marine science in fostering an informed, engaged society capable of addressing the challenges and opportunities of our changing oceans. As environmental pressures intensify, and marine resource demands increase, Australians’ capacity to engage with ocean issues, understand risks and opportunities, and participate in marine decision-making has never been more urgent. Marine science will play a central role in building ocean literacy by delivering credible, actionable science, and strengthening education and training systems that enhance understanding of, and connection to, the ocean. Our …

Reclaiming Constitutional Authority Of Algorithmic Power, Yiyang Mei, Michael J. Broyde

Faculty Articles

Whether and how to govern AI is no longer a question of technical regulation. It is a question of constitutional authority. Across jurisdictions, algorithmic systems now perform functions once reserved to public institutions: allocating welfare, determining legal status, mediating access to housing, employment, and healthcare. These are not merely administrative operations. They are acts of rule. Yet the dominant models of AI governance fail to confront this reality. The European approach centers on rights-based oversight, presenting its regulatory framework as a principled defense of human dignity. The American model relies on decentralized experimentation, treating fragmentation as a proxy for democratic …

Do Emerging Social Media Platforms Shape The Gender Gap In Surveillance Political Knowledge?, Saskia Papsova

Graduate Studies Theses and Dissertations 2026

Abstract

Research shows that men consistently score higher than women on standard political knowledge measures, but as Americans increasingly obtain political information through social media, it is unclear whether different platforms affect this gender gap. This study investigates whether social media platforms shape the gender gap in surveillance political knowledge—knowledge of current political facts and contested claims circulating in the contemporary information environment, and which platforms have the biggest impact. Using data from the ANES 2020 Social Media Study, I estimate weighted OLS regression models testing whether platform-specific usage is associated with surveillance political knowledge and whether these associations differ …

A Sensory Ecology Of Fear: Moonlight-Mediated Predation Risk And Foraging Behavior In Neotropical Electric Fish, Chiu Lok Poon

Graduate Studies Theses and Dissertations 2026

Animals must forage to acquire energy for survival and reproduction, yet foraging exposes them to predators. This creates a trade-off between energy intake and safety, wherein the perception of predation risk alone can alter activity patterns. Within this trade-off, risk, energetic needs, and sensory adaptations vary, shifting the balance and favoring different foraging strategies. Using Neotropical electric fish as a study system, I investigated how foraging under predation risk is shaped across biological scales, including environmental dynamics, interspecific sensory differences, activity-timing mechanisms, and intraspecific variations. These nocturnal fish emit continuous electric signals to sense their environment, allowing non-invasive monitoring of …

Forest Island Reforestation In The Llanos De Moxos, Bolivia, Ethan Tam

Graduate Studies Theses and Dissertations 2026

Within the Llanos de Moxos of Bolivia thousands of forest islands dot the landscape. These forest islands have been shown to have been integral aspects of the pre-Contact indigenous cultures which existed there for thousands of years. Based on 1967 CORONA imagery and statistical analysis, this work provides insight into how these forest islands are integrated as infrastructure features within their landscape and surrounding network of other archaeological features. This research is carried out through investigations into changes in the size of the forest islands across an interval of 57 years, statistical attempts to categorize the forest island into smaller …

Optically-Pumped Semiconductor Optical Amplifiers, Dhruvkumar Desai

Graduate Studies Theses and Dissertations 2026

Semiconductor optical amplifiers (SOAs) offer a low-cost, compact solution for power amplification needs in an optical communication system compared with the dominant erbium-doped fiber amplifiers (EDFAs). They can also provide a wide gain bandwidth. However, conventional electrically-pumped SOAs suffer from larger noise figures, low saturation power, and polarization dependence, in comparison with EDFAs. We propose an optically-pumped SOA (OP-SOA) that will maintain the benefits of conventional SOAs while closing the gaps in other amplifier performance metrics. The underlying reasons for optical pumping are twofold. First, optical pumping allows higher carrier injection and thus "population inversion." Second, optical pumping decouples carrier …

Minimizing Performance Overheads For Crash-Consistency In Disaggregated Persistent Memory, Khan Shaikhul Hadi

Graduate Studies Theses and Dissertations 2026

Compute express link (CXL) enables persistent memory disaggregation with memory pooling and hardware managed multi-host memory sharing capability, resulting in better resource utilization, increased scalability. Persistency-aware applications need to manage crash consistency across the system which results in significant performance overhead. This dissertation systematically investigates performance overhead to achieve crash consistency in disaggregated persistent memory and proposes solutions to enable persistency-aware application scaling for distributed system. First, we study persistent parallel programming to scale computation capability beyond single processor and determine the underlying hardware limitation to adopt lock-free data structure. We propose hardware support to design durable atomic instruction (DAI) …

Connecting The Existing Fiber Infrastructure To The Future With Antiresonant Hollow Core Fibers, Timothy Bate

Graduate Studies Theses and Dissertations 2026

Optical fiber systems based on solid-core silica waveguides underpin modern telecommunications, high-power laser delivery, precision sensing, and coherent optical systems. However, nonlinear effects, material absorption, and thermal limitations within silica increasingly constrain further scaling in both optical power and transmission performance. Antiresonant hollow-core fibers provide a promising alternative by guiding light predominantly in air, substantially reducing nonlinear interactions, latency, and optical damage while enabling transmission regimes inaccessible to conventional solid-core fibers. Despite rapid advances in antiresonant hollow-core fiber attenuation and power handling, one of the largest remaining barriers to widespread adoption is reliable integration with the existing solid-core fiber ecosystem. …

Human-Centered Governance Of Climate Resilience: Integrating Sustainability, Equity, And Mental Health, Chelcee A. Pangerl

Graduate Studies Theses and Dissertations 2026

This dissertation examines how sustainability and resilience are defined, implemented, and experienced across three levels of climate governance: household perception, community experience, and federal policy. Climate resilience is often evaluated through infrastructure performance, emissions targets, restoration timelines, and preparedness systems, yet these measures do not fully capture how residents experience uncertainty, support, equity, and mental health. To address this gap, the dissertation develops and applies the Integrated Policy Framework for Sustainability and Resilience (IPFSR). IPFSR organizes six domains into three functional categories: policy outcomes, human-centered dimensions, and implementation mechanisms. Sustainability and operational/physical resilience are treated as policy outcomes; mental health …

The Case For Friction In Ai-Mediated Information Seeking And Learning, Susan G. Archambault, Priya Kizhakkethil

Librarian Publications & Presentations

Introduction. This paper challenges the assumption that frictionless AI-mediated information seeking represents progress. We argue that AI systems eliminating productive friction, such as uncertainty, exploration, and reflective processes, undermine intellectual virtues essential for critical thinking in an AI-saturated information environment.

Method. This conceptual article employs a theory synthesis approach, drawing on library information science (LIS) theories of information behaviour, experience, and literacy, virtue epistemology, and human–computer interaction (HCI) friction design literature.

Analysis. We map intellectual virtues such as curiosity, thoroughness, and intellectual humility onto the Association of College and Research Libraries (ACRL) Framework for Information Literacy for Higher Education, building …

Vape Counseling At Pediatric Practices: The Rethink Vape Toolkit, Paul T. Harrell, Ann L. Edwards, Natasha K. Sriraman, Rebecca J. Slimak, Anisha S. Vanka, Amy C. Paulson, Kelli J. England

Department of Pediatrics Faculty Publications

Introduction:

E-cigarettes (Vapes) represent the most common form of tobacco used by adolescents, with one out of every 29 (3.5%) middle school students and one in every 13 (7.8%) of high school students vaping daily. This project aimed to increase vape screening and prevention education in youth visits at pediatric practices, to increase provider comfort with the topic of vaping, and to evaluate this educational process.

Methods:

A provider training and resource modules (talking points, billing codes, and shareable parent/teen-tailored resources) were developed. Providers (N = 32) completed an anonymous pre/postsurvey regarding their knowledge, comfort levels, barriers, and practices related …

Causal Effect Estimates Of Online E-Cigarette Marketing Exposure On Future E-Cigarette Harm Perception And Use, Paul T. Harrell, Nicholas T. Williams, Kara E. Rudolph, Rachel Ayala Guzman, Ateeqa Ijaz, Nicole Rychagov, Aaron Null, Silvia S. Martins

Department of Pediatrics Faculty Publications

Background

Globally, over 10 million youth use e-cigarettes; United States use, in particular, dramatically rose in the late 2010's, exceeding year-over-year increases from any other substance in over four decades. This rise has been partially attributed to youth online e-cigarette marketing exposure, but has not been appropriately studied.

Methods

We examined youth data from the Population Assessment of Tobacco and Health (PATH) spanning the dramatic increase period (Waves 4, 4.5, and 5; 2016-2019). We estimated average risk differences (RD) for Wave 5 e-cigarette harmfulness perception and use comparing all youth versus no youth reporting past-month online e-cigarette marketing exposure in …

35 Individuals With Huwe1-Related Neurodevelopmental Disorder And Suggested Clinical Evaluations, Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillman, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano

Department of Pediatrics Faculty Publications

HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X-linked intellectual disability, including in the patients identified by Juberg, Marsidi, and Brooks. This report describes 35 additional cases of individuals with variants in HUWE1 and suggested guidelines for clinical management. Our study includes several female cases, which have not been widely reported previously. Our findings confirm earlier reported clinical features including developmental delay, autism, hypotonia, short stature, and dysmorphic facial features as well …