Digital Commons Network^™

Hyperacute Interleukin-1Β Production And Neutrophil Extracellular Trap Formation In The Cerebral Circulation Of Stroke Patients With Large Vessel Occlusion, Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa

Neurology Faculty Publications

Objective: Cerebral ischemia remains a major cause of disability, and the contribution of the hyperacute immune response is increasingly recognized. The aim of this study was to investigate the local inflammatory response in the affected brain of stroke patients with large vessel occlusion during the hyperacute phase of stroke. Methods: To decipher the role of myeloid immune cells in stroke-induced inflammation, we performed an unsupervised multiomics analysis of innate immune pathways in ischemic blood obtained directly from the occluded middle cerebral artery in 54 patients undergoing mechanical recanalization. Paired nonischemic arterial blood served as an internal control. Results: Stroke triggered …

Post-Approval Study 3-Year Outcomes Of The Neuroform Atlas Stent For The Treatment Of Wide-Necked Intracranial Aneurysms, Brian Jankowitz, Ashutosh P. Jadhav, Bradley Gross, Tudor G. Jovin, Abdulnasser A. Alhajeri, Justin F. Fraser, Ricardo A. Hanel, Eric Sauvageau, Amin Aghaebrahim, Donald Frei, Richard Bellon, David N. Loy, Ajit S. Puri, Adel M. Malek, Ajith J. Thomas, Gabor Toth, Demetrius Klee Lopes, R. Webster Crowley, John Reavey-Cantwell, Eugene Lin, Adnan Siddiqui, Michael J. Alexander, Ahmad Khaldi, Geoffrey P. Colby, Justin M. Caplan, Sudhakar R. Satti, Aquilla S. Turk, Alejandro M. Spiotta, Richard Klucznik, Danial K. Hallam, David Kung, Michael T. Froehler

Neurology Faculty Publications

Introduction The ATLAS trial was a prospective, multicenter, single-arm, investigational device exemption (IDE) study to evaluate the safety and effectiveness of the Neuroform Atlas Stent System for the treatment of widenecked bifurcation aneurysms. This analysis presents the 36-month follow-up data for the anterior and posterior cohorts. Methods Of the 182patients in the IDE anterior cohort, 146 consented to participate in the post-approval study (PAS) and, of the 116patients in the IDE posterior cohort, 101 consented to participate in the PAS. The primary effectiveness endpoint was core laboratory adjudicated (Raymond–Roy 1; RR1) without retreatment or parent artery stenosis (>50%) at …

Why Are Executions Becoming Crueler?, Deborah W. Denno

Faculty Scholarship

Since the modern death penalty era, this country’s six execution methods have become crueler over time. This article details the execution procedures adopted across death penalty states up to the end of 2025, analyzing their societal and cultural underpinnings and explaining how they were implemented, including their shared flaws, unscientific origins and protocols, and reliance on untrained, unqualified, or unknown executioners. While legislatures and courts claim that states move from one technique to the next to enhance greater humaneness, history shows that such switches are primarily propelled by constitutional challenges to a state’s particular technique. In theory, rendering a state’s …

Should Statutory Interpretation And Contract Interpretation Be Harmonized?, Ethan J. Leib

Faculty Scholarship

This paper develops four case studies about how states have harmonized or separated their statutory interpretation regimes and their contract interpretation regimes.  After exploring the choices of Texas, Alaska, New York, and Alabama—all of which take different approaches to their lumping or splitting—the paper seeks to make state courts more aware of what their options are; to help states think about whether their commitments to formalism or contextualism make sense to apply in both domains; and to help them evaluate their meta-choices about whether to bring their interpretive regimes closer together or further apart.

Women's Work And Wealth: Measuring The Impact Of Incremental Liberations, 1850-1870, Hannah Kelly

Williams Honors College, Honors Research Projects

Using a two-way fixed effects difference-in-difference model, this project analyzes data from the IPUMS Full Count census for 1850, 1860, and 1870 at a state level for 48 states. Four models assess the impact of property laws on women's real property holdings, labor force participation, household types, and real property values.

By quantifying the impact of various legal reforms on women's economic empowerment, this project fills a gap in the understanding of the intersection between law, society, and women's economic agency during a transformative period in pre-industrial American history. These impacts can implicate the effectiveness of legislative measures in advancing …

A 1d Symmetric Interior Penalty Discontinuous Galerkin Solver In Rust, William Aey

Williams Honors College, Honors Research Projects

This honors project will build a 1D Symmetric Interior Discontinuous Galerkin (SIPDG) solver in Rust for Stum-Liouville type problems such as the Poisson equation, with Robin, Dirichlet, and Neumann boundary conditions. The work will cover the full pipeline: starting from the strong form of the PDE, deriving the DG weak form, implementing element and interface operators, and assembling or apply the discrete operator. Rust's safety and concurrency (e.g, via Rayon) will be used to explore serial and parallel performance. A test-driven development approach will be used to maintain a strong suite of tests. The project will result in a documented …

Ai-Based Porosity Detection In Babbitt Bore Turning, Kaylee Leggett, Hannah Adams Gemmell, Kaisa Shingleton

Williams Honors College, Honors Research Projects

For this project, an external company reached out to the University of Akron requesting assistance with defect detection during their vertical turning operations. As babbitt is removed in a vertical turning process, it occasionally reveals defects, mainly porosity, which can lead to costly downstream failures of the part. Current inspection techniques involve use of dye penetrant, which is time consuming, labor intensive, unergonomic, and a source of human error. The goal of the project is to create an alternative inspection method using an AI-based machine-learning model. After the turning operation, a camera is deployed to perform an in-place inspection, taking …

Printer For Music Box, Chad Lewis, Caleb Murawski, Zion Smith, Bryan Tibbs

Williams Honors College, Honors Research Projects

The traditional method of creating music box sheet music involves manually punching holes into a paper strip using a hand-operated hole punch. This process involves precise knowledge of each note’s location and the ability to achieve perfect accuracy for hours.

The goal of this system is to automate this process, significantly reducing the time required while greatly improving the accuracy of the resulting music box playback. The user simply uploads a MIDI file of their choice into a user-friendly application. Here, the file is modified based on the user’s needs and sent to an automated hole-punching system to punch the …

Crashheart, Ellie Riekert, Kennady Skidmore, Madison Furino

Williams Honors College, Honors Research Projects

This project aims to develop an XR (extended reality) iPad training system to improve pediatric crash cart preparedness among nurses and clinical staff at Akron Children’s Hospital. In emergencies such as respiratory failure or shock, quick and accurate access to crash cart supplies is vital, yet opportunities for hands-on practice are limited. Current nurse training relies on PowerPoint instruction or costly physical simulations, reducing engagement and skill retention. Our interactive XR solution replicates the crash cart’s layout and contents, allowing users to practice identifying and retrieving critical items in a realistic environment without using physical supplies. The system will be …

Seat Belt Data Collection Methods: A Comparison Between States And National Guidelines, Madison R A Richards

Williams Honors College, Honors Research Projects

Thousands of fatalities related to vehicle crashes occur every year. One method to reduce fatalities is to encourage seat belt use compliance. To promote statistics regarding seat belt use, there first must be reliable data on seat belt compliance and this comes from good survey design.

This report is a comparative analysis of seat belt data collection methodologies for Ohio, Michigan, and Indiana, in addition to an evaluation of how each state aligns with standards set by the National Highway Traffic Safety Administration (NHTSA). The framework for this analysis focuses on NHTSA’s five core survey design requirements: selection of observation …

Supporting Mothers Within The Criminal Legal System: Programs In Akron And Perceptions Of “Good Motherhood”, Brynn R. Lewis

Williams Honors College, Honors Research Projects

This paper examines the programs and support systems available in Akron, Ohio, for mothers involved in the criminal legal system, including defendants, survivors, and other justice-involved individuals. Using qualitative interviews (n = 6) with professionals across courts, legal defense, community corrections, and advocacy organizations, this study examines how local institutions provide resources and support to mothers. Findings indicate that while programs aim to promote stability and rehabilitation, mothers face persistent barriers such as limited access to transportation, childcare, and communication, as well as heightened stigma tied to societal expectations of caregiving. These findings reveal that institutional support both reflects and …

Security Onion Ids Case Study: Detecting And Investigating Threat Traffic Using Suricata, Zeek, And Pcap Evidence, Daryna Myroniuk

Williams Honors College, Honors Research Projects

A key component of cybersecurity is network intrusion detection, which is used to examine network traffic for any malicious activity. Many organizations deploy intrusion detection systems (IDS) but still face challenges such as validating detections, investigating alerts in a timely manner, and producing clear and repeatable evidence of what has occurred, especially when live traffic capture may be limited to risks, permissions, or privacy concerns. The goal of this project was to use Security Onion, which includes Suricata and Zeek to create and demonstrate a controllable and manageable evidence-based IDS investigation workflow. This project is focused on deploying and validating …

Stanislavski And Operatic Acting: What Caused The Divide Between Stanislavski’S Ideals And The Opera World?, Max Smith

Williams Honors College, Honors Research Projects

There is a difference between the realism of acting in opera and in other theatrical art forms. One reason for this might be due to theatre practitioner Konstantin Stanislavski’s ideals not being readily adopted in the opera world. Due to translation and publication issues in both the West and in the USSR, his work on opera has been largely neglected by theatre and opera historians. Certain demands of opera as an art form limit or make more difficult the ability for realism in portraying a character, but Stanislavski and others show that it is possible. A look at literature reflecting …

Defending A Soho Network Against Mitm Attacks, Braeden J. Wise

Williams Honors College, Honors Research Projects

Cybersecurity is a vast domain that consists of many threats that target sensitive information found on wired and wireless networks. One of those threats is a man-in-the-middle (MITM) attack, which involves an attacker situating themselves between a sender and a receiver to intercept or redirect network traffic. These kinds of attacks can run rampant on a small office home office (SOHO) network due to the vulnerabilities and lack of enterprise level tools. The intent of this project is to perform and defend against MITM attacks for a SOHO network. In the context of the project, three MITM attacks will be …

Analyzing Network Traffic And Data Exfiltration Via Smb In Post-Vm Escape Scenarios, Noah M. Disanza

Williams Honors College, Honors Research Projects

Virtual machines (VMs) play a crucial role in modern IT infrastructure environments by providing isolation and enhanced security, among other things, for both personal and corporate systems. VMs are heavily rely upon to safely test malware, manage infrastructure, and reduce risk to host systems. This reliance is so substantial that the idea of reducing risk to the host system is believed to be erasing risk entirely. However, this mindset has shown to be challenged time and time again by the emergence of exploits known as virtual machine escapes. These exploits allow malicious actors to break out of the virtualized environment …

Rapid Skin Stapler, Emma J. Patterson, Allison M. Milligan, Morgan E. Dunlap

Williams Honors College, Honors Research Projects

Severe burn injuries frequently require split-thickness skin grafts, with metal surgical staples serving as the current standard for fixation. While staples provide rapid and secure placement of graft material, they also introduce significant challenges. Removal is painful, time-consuming, and often requires sedation in pediatric patients, leading to added risk, resource strain, and poor patient experience. These drawbacks highlight the need for improved fixation methods that maintain graft stability while reducing procedural burden. This project applies the engineering design process to address these challenges through identification of user needs, translation into design inputs, risk assessment, and development of a prototype aimed …

Reconstructing Lost Voices, Lana Tamim

Williams Honors College, Honors Research Projects

This project uses digital text mining tools (OCR, NLP, sentiment analysis, and topic modeling) to analyze 19th–20th-century newspaper archives, focusing on how marginalized groups (women, immigrants, or labor workers) were historically portrayed. Many historical newspapers were dominated by elite voices, so this project aims to recover silenced or misrepresented perspectives by identifying hidden patterns in language, frequency of coverage, sentiment, and shifts in public perception over time. Using machine learning and visualization tools, the project will create interactive maps and timelines showing how representation evolved across regions.

Redrawing Anatomy: Addressing Female Genital Underrepresentation In Educational Texts, Clara E. Krohn

Williams Honors College, Honors Research Projects

The fight for female equality in the historically male dominated medical field is an ongoing battle. This project focuses primarily on the underrepresentation of female genitalia in undergraduate academic textbooks. A dissected pelvis of a female cadaver was initially examined. Pictures were obtained with scale bars to accurately depict size of the structures included. Underrepresented structures such as the clitoris and the broad ligament were closely examined along with the reproductive system as a whole. The pictures compiled along with further research were used to design a portfolio of diagrams and a survey to be later administered. The survey was …

Immigration As A Catalyst To The Far-Right: The Case Of Vox And Spain, Evelyn R. White

Williams Honors College, Honors Research Projects

Over the last decade or two, the world has witnessed a global rise in the popularity and success of far-right wing parties. This new era of the radical right raises questions of what is causing and fueling these political movements. Political Scientists have identified several contributing factors from the global economic crisis of 2008, the migrant crisis of 2015 and the global pandemic in 2020. This research paper aims to demonstrate how immigration acts as a catalyst to the far-right by intersecting with political science ideologies and other variables. The focus of this paper is how the Vox Party found …

Designing Crime Prevention And Crowd Management Plans For The New Berea Campus Expansion Project For The Cleveland Browns, Elleana G. Grant

Williams Honors College, Honors Research Projects

The Cleveland Browns are expanding their CrossCountry Mortgage Campus by 16 acres. This research seeks to answer a core question: How can the design of the new expansion support both crime prevention and effective crowd management for events drawing up to 6,000 guests? Additional research questions include identifying the safety risks associated and determining which evidence-based strategies are most appropriate. The main goal of this research is to ensure that the expanded campus is safe for all visitors. This work is motivated by the significant increase in daily activity that the expansion will bring, not only during major events, but …

Designing Intentionally: Color Psychology In Graphic Design, Savannah Jons

Williams Honors College, Honors Research Projects

This study will explore the role of color in graphic design and the psychological processes behind viewersʼ emotional and perceptual responses. Research will investigate how color psychology is influential on design, how the selection of color guides design appeal, and how it can alter commercial messaging.

Ai-Based Music Mood Analysis With Historical And Real-Time Data, Biswash Bhattarai

Williams Honors College, Honors Research Projects

The Music Mood Analyzer Dashboard identifies and visualizes the emotional tone of songs using audio features like tempo, energy, and valence. It classifies tracks into moods such as happy, sad, or calm and presents insights through an interactive dashboard. The project combines music analysis and data visualization to help users understand how sound relates to emotion.

The Impact Of Night Shift On New Nurses: Effects On Mental Health And Work-Life Balance, Avery Windham, Abby Maruskin, Elizabeth Yoder

Williams Honors College, Honors Research Projects

This research examines the impact of night shift schedules on new nurses' mental health and work-life balance as they transition into professional practice. The transition from nursing school to the workforce presents challenges that are further compounded by shift work, which can disrupt circadian rhythms and contribute to stress, fatigue, and reduced job satisfaction. The purpose of this research is to evaluate how starting on night shift versus day shift influences nurses’ self-evaluation of work-life balance within their first year of practice. This systematic review synthesizes findings from peer-reviewed sources to assess the physical, emotional, and professional consequences of night …

Effects Of Hofmeister Ions On Lower Critical Solution Temperatures Of Poly(N-Isopropylacrylamide) And Poly(Vinyl Methyl Ether), Joseph Joaquin

Williams Honors College, Honors Research Projects

The goal of this study is to compare how four different Hofmeister anions (Cl-, SCN-, F-, and I-) affect the Lower Critical Solution temperature (LCST) on two thermo-responsive polymers: poly(N-isopropylacrylamide) (pNIPAAM) and poly(vinyl methyl ether) (PVME). pNIPAAm is commonly used in the environmental applications such as monitoring, oil-water separations, or antifouling materials, and in medical industry from drug delivery to tissue engineering. When pNIPAAM or PVME reaches a temperature above their LCST, they become hydrophobic, and the polymer chains coiled, leading to their aqueous solutions turn opaque. PVME exhibits a similar LCST as that of pNIPAAM, so it can be …

The Compass, Summer 2026

The Compass, 2018-

The Compass is an annual orientation guide for VCU students produced by the Student Media Collective in the VCU Student Media Centered. The guide is distributed physically during summer orientation sessions for new and transfer students. The publication includes short articles, illustrations, letters of welcome from students and administrators, comics, and advertisements from VCU and Richmond organizations.

Pitch Report: Purdue Ivy Tech Chips Evaluation Report, Jennifer Sdunzik

Evaluation and Learning Research Center Reports

The Purdue Ivy Tech CHips (PITCH) program is a university-industry-community partnership aimed at developing an educational pipeline capable of providing a qualified workforce for the growing semiconductor industry in the region. Increasing student interest in microelectronics, awareness of current and future microelectronics careers, and self-efficacy to pursue microelectronics opportunities are foundational to building the industry’s workforce. The PITCH program addressed these needs by offering a summer experience that introduced high school students to the semiconductor industry.

The PITCH leadership team engaged Purdue's Evaluation and Learning Research Center (ELRC) to (1) identify (short and longer-term) impacts of the summer program on …

“It Feels Like A Safe Container”: Experiences Of Finding Solid Ground Groups For Adults With Dissociative Disorders., Laura Hawkins, Sarah Chipps, Kim Foreman, Stephanie Johnson, Aimee Mccann, Rebecca Braughton, Abidemi Mary Ajuwon, Dongjuan Xu

School of Nursing Faculty Publications

Objective: Dissociative disorders (DD) are trauma-related conditions marked by disruptions in memory, identity, and consciousness. Despite high prevalence, DDs are underdiagnosed and undertreated. This study explores the experiences of adults with DD participating in a 31-week Finding Solid Ground (FSG) psychoeducational group. Method: Participants (N=72) were mostly women (81%), who experienced a DD or PTSD dissociative subtype, along with multiple mental health comorbidities. Eight groups (seven virtual, one in-person) completed 31 weekly 90-minute sessions based on the FSG curriculum as adjunctive to individual psychotherapy. Thematic qualitative analysis was used to analyze participants’ hopes, challenges, helpful and unhelpful aspects, and perceived …

Simplified Traffic Studies For Local Agencies, Laura Slusher

Indiana Local Technical Assistance Program (LTAP) Publications

Traffic studies are critical in the decision-making process for many transportation-related projects, funding requests, paving and plowing priorities, and in reporting to elected officials and the public. It is often difficult for local jurisdictions with limited equipment, staff, and time to perform these studies or have the funds available to hire them out. This handbook describes simplified procedures that are easy to apply and are written for all potential users.

Stem Integration Through Environmental Data Analysis For Real-World Problem Solving, Abigail Erskine

Indiana STEM Education Conference

Integrating authentic, environmental-based data can make STEM instruction more meaningful. As part of a broader high school STEM curriculum, I designed a lesson that connects mathematical and statistical concepts, technology, and environmental data through environmental data analysis to develop real-world problem solving. Using local deer mortality data, I examined how descriptive statistics and data interpretation could reveal population and ecological patterns. Designing with real data highlighted how mathematics can serve as a lens for understanding environmental issues and promote connections across STEM disciplines. This research brief focuses on the instructional design and reflection as the lesson designer.

Breech Baby, Madison Kaufman, Cassidy Allen, Lilian Mills

Williams Honors College, Honors Research Projects

Our project aims to develop a non-invasive device to assist in turning breech babies to a head down position before delivery. Pregnant women facing breech presentations often need safe and effective solutions, yet current options like external cephalic version (ECV), maternal positioning techniques, and cesarean sections can present challenges. Key barriers include variability in maternal and fetal anatomy, patient comfort, compliance, and training for healthcare providers, along with cost and insurance concerns.

Our innovative device will address these issues by providing clear guidance and support throughout the process. It will prioritize minimizing discomfort and risk, ensuring adaptability for various stages …