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Articles 31681 - 31710 of 1517247
Full-Text Articles in Entire DC Network
Following The Thread: Maria Lai’S 1981 Legarsi Alla Montagna, Claire Borre
Following The Thread: Maria Lai’S 1981 Legarsi Alla Montagna, Claire Borre
Theses and Dissertations
This thesis examines Maria Lai’s (1919-2013) Legarsi alla montagna (1981), a three-day, relational project in which seventeen miles of ribbon were wound through the Sardinian town of Ulassai. In its conception, execution, and legacy, Lai’s project represented a significant challenge to traditional monumentality.
Fugitive Formalisms: Strategies Of Dissemblance And Dissent In The Work Of Queer-Identifying Artists, 1970–Present, Rowan Diaz-Toth
Fugitive Formalisms: Strategies Of Dissemblance And Dissent In The Work Of Queer-Identifying Artists, 1970–Present, Rowan Diaz-Toth
Theses and Dissertations
Utilizing case studies of works by Hélio Oiticica, Scott Burton, and Felix Gonzalez-Torres as points of departure, this thesis puts forth a speculative historical framework for reconsidering queer art practices up through the present day in opposition to regimes of visibility and transparency, exploring the subversive, fugitive potential of non-representational formalisms.
Rhetorical Awareness And Vision In The Four Speeches Of Ellison’S Invisible Man, Asif Ibrahim
Rhetorical Awareness And Vision In The Four Speeches Of Ellison’S Invisible Man, Asif Ibrahim
Theses and Dissertations
This thesis evaluates Ralph Ellison’s account of rhetoric’s role in establishing, disguising, and contesting racism in the early- and mid-twentieth-century United States. The thesis is structured around four pivotal public orations by the protagonist of Ellison’s 1952 novel Invisible Man. Drawing on Ellison’s private letters and essays to further illuminate his concern for the relationship between speech, public engagement, and self-perception, I propose that Ellison’s novel dramatizes some ways that shifts in speech style, technique, and addressee enable intellectual development and political efficacy. Even techniques that initially appear self-sabotaging and “blind,” Ellison suggests, have the potential to develop into politically …
Simulation Of Quantum Walks For Secure Data Access Patterns, Arslan Ahmad Janjua
Simulation Of Quantum Walks For Secure Data Access Patterns, Arslan Ahmad Janjua
Theses and Dissertations
Quantum computing is revolutionizing computational science, offering fundamentally new approaches to information processing that surpass classical limitations. One of the most versatile and powerful tools in this emerging field is quantum walks. Quantum walks are quantum analogs of classical random walks that leverage superposition and interference to explore complex spaces efficiently.
This thesis will explore how discrete-time scattering quantum walks can be simulated and analyzed to investigate patterns of secure data access. By modeling quantum walks on a variety of graph structures and studying the dynamics of marked vertices, the project aims to demonstrate how quantum interference and graph topology …
The Decadent Bible: Biblical Intertextuality In Flaubert’S Herodias And Wilde’S Salome, Shoshana Mintz
The Decadent Bible: Biblical Intertextuality In Flaubert’S Herodias And Wilde’S Salome, Shoshana Mintz
Theses and Dissertations
This paper argues that Gustave Flaubert’s Hérodias and Oscar Wilde’s Salomé incorporate biblical intertextuality throughout their work as a means to showcase Decadent technique and themes. Both authors weave direct quotations from biblical sources such as the Gospels of Matthew and Mark, Isaiah, Ezekiel, Revelation, and Acts into their texts, layering biblical passages with themes of excess, eroticism, and decay central to the Decadent movement. Drawing on Julia Kristeva’s theory of intertextuality, I show how these biblical fragments intersect with narrative voice to destabilize meaning and form a unique, new work of writing that intertwines their own words with biblical …
O Esqueleto De Um Romance, Lanna Leite
O Esqueleto De Um Romance, Lanna Leite
Theses and Dissertations
In O Esqueleto de um Romance: The Film (2025), a Berlin legal dispute between a mayor and evangelicals sparks filmmaker Lanna Leite’s reflection on faith, memory, and belief. Using archival, 16mm, and 8mm footage, the experimental film frames filmmaking as an ephemeral, performative practice resisting closure and conventional narrative finality.
The Double Gaze: Weaving Historical, Decolonial, And Indigenous Perspectives Through Maruch Sántiz Gómez’S Creencias., Elisa Gutiérrez Eriksen
The Double Gaze: Weaving Historical, Decolonial, And Indigenous Perspectives Through Maruch Sántiz Gómez’S Creencias., Elisa Gutiérrez Eriksen
Theses and Dissertations
The Double Gaze examines Maruch Sántiz Gómez’s series Creencias (1994-2000) at the intersection of sociopolitical changes in southeastern Mexico and the 1995 Johannesburg Biennial. Drawing on Rita Segato’s “capillary disobedience” and the Mayan philosophy of kab’awil, the research considers Creencias as a theoretical proposal for reading Indigenous art practices.
Structural Characterization Of Peptide Nanoaggregates At Varying Concentrations And Their Impact On Cellular Responses, Malika Rozmetova
Structural Characterization Of Peptide Nanoaggregates At Varying Concentrations And Their Impact On Cellular Responses, Malika Rozmetova
Theses and Dissertations
Peptide nano-assemblies can regulate cellular pathways in a structure-dependent manner. Here, we show that the enzyme-responsive peptide NapFFK(NBD)Yp forms distinct nanoscale assemblies at different concentrations, triggering differential ER stress and extracellular vesicle release in MDA-MB231 cells. These results highlight the importance of supramolecular organization in peptide–cell interactions.
One Stone's Journey, Satoko Saito
One Stone's Journey, Satoko Saito
Theses and Dissertations
One Stone’s Journey is a participatory, experiential thirty-minute documentary about uranium. By using an embroidered world map and appealing to participants’ senses—especially touch—the project explores the possibility of telling the story of radiation, which is invisible, intangible, and silent. Uranium is a radioactive material used by the United States in the development and production of the atomic bombs during the Manhattan Project. This year, 2025, marks the 80th anniversary of the atomic bombings of Hiroshima and Nagasaki. The Fukushima Daiichi nuclear power plant accident in 2011 was on a scale comparable to the Chernobyl disaster of 1986, and the threat …
Risk And Public Judgments On Police Pursuits: A Nationally Representative Conjoint Experiment, Scott M. Mourtgos, Ian T. Adams, Kyle Mclean, Geoffrey P. Alpert
Risk And Public Judgments On Police Pursuits: A Nationally Representative Conjoint Experiment, Scott M. Mourtgos, Ian T. Adams, Kyle Mclean, Geoffrey P. Alpert
Faculty Publications
Police vehicle pursuits emphasize a central tension between law enforcement imperatives and public safety. While modern policies emphasize balancing apprehension needs against risks of continuation, little is known about whether public intuitions mirror this framework. We address this gap using a nationally representative conjoint experiment (N = 3,334) that varied eleven contextual factors across randomized pursuit scenarios. Respondents rated perceived risk, indicated whether pursuits should be terminated, and made forced-choice tradeoffs. Across all outcomes, high-risk situational factors (e.g., high speeds, adverse weather, heavy traffic, urban settings, etc.) increased perceived danger and termination support, while more serious underlying offenses, particularly …
Effects Of Ai Transparency On Perceived Fairness In Ai-Driven Selection Tools: The Mediating Roles Of Ai Literacy And Attitudes Towards Ai, Tony Mellek
Industrial-Organizational Psychology Dissertations
Artificial intelligence is becoming an increasingly prominent feature of modern hiring, creating opportunities to enhance efficiency and consistency in selection. This study examined how AI transparency, AI literacy, and attitudes toward AI shape applicants’ perceptions of fairness when engaging with AI-scored pre-hire assessments. A sample of 290 U.S. adults were randomly assigned to either a high- or low-transparency hiring scenario and then completed measures of AI literacy, attitudes toward AI, and procedural fairness. Results indicated that both AI literacy and attitudes toward AI were strong and significant predictors of perceived procedural fairness, suggesting that applicants who feel knowledgeable about AI …
Light Is Not Always Right: Peri-Iridial Lightness Reduces Attractiveness Via Perceived Sex-Typicality Across Human Populations, Vojtěch Fiala, Juan Olvido Perea-García, Petr Tureček, Sławomir Wacewicz, Juan David Leongómez, Šimon Pokorný, Ondřej Pavlovič, S. Adil Saribay, Farid Pazhoohi, Robert Mbe Akoko, Karel Kleisner
Light Is Not Always Right: Peri-Iridial Lightness Reduces Attractiveness Via Perceived Sex-Typicality Across Human Populations, Vojtěch Fiala, Juan Olvido Perea-García, Petr Tureček, Sławomir Wacewicz, Juan David Leongómez, Šimon Pokorný, Ondřej Pavlovič, S. Adil Saribay, Farid Pazhoohi, Robert Mbe Akoko, Karel Kleisner
School of Psychology
Abstract: Evolutionary psychology views the human eye as special. In particular, it claims that the light peri-iridial tissues surrounding a relatively darker iris form a combination that sets us apart from other primates. From this perspective, much less attention has been paid to how eye colouration varies between humans, although evidence indicates that variations in peri-iridial and iridial colouration influence both perceived facial attractiveness and sex-typicality. To determine what aspects of eye colouration influence the perception of faces, we have measured the colour of peri-iridial eye tissues (‘the white of the eye’) and the iris in nine samples from seven …
Making Waves Through Expedition, Jenna Malloy, Natalia López-Figueroa, Ana Arellano
Making Waves Through Expedition, Jenna Malloy, Natalia López-Figueroa, Ana Arellano
Making Waves REU
No abstract provided.
Cholesterol Efflux Protein, Abca1, Supports Anticancer Functions Of Myeloid Immune Cells, Shruti V Bendre, Yu Wang, Basel Hajyousif, Rajendra K C, Shounak G Bhogale, Dhanya Pradeep, Natalia Krawczynska, Claire P Schane, Erin Weisser, Avni Singh, Simon Han, Hannah Kim, Lara Kockaya, Anasuya Das Gupta, Adam T Nelczyk, Hashni Epa Vidana Gamage, Yifan Fei, Desirée Rodríguez-Casiano, Xingyu Guo, Haoyun Li, Ryan J Deaton, Fei Mo, Maria Sverdlov, Peter H Gann, Saurabh Sinha, Sahil Sahni, Kun Wang, Kevin Van Bortle, Emad Tajkorshid, Wendy A Woodward, Wonhwa Cho, Erik R Nelson
Cholesterol Efflux Protein, Abca1, Supports Anticancer Functions Of Myeloid Immune Cells, Shruti V Bendre, Yu Wang, Basel Hajyousif, Rajendra K C, Shounak G Bhogale, Dhanya Pradeep, Natalia Krawczynska, Claire P Schane, Erin Weisser, Avni Singh, Simon Han, Hannah Kim, Lara Kockaya, Anasuya Das Gupta, Adam T Nelczyk, Hashni Epa Vidana Gamage, Yifan Fei, Desirée Rodríguez-Casiano, Xingyu Guo, Haoyun Li, Ryan J Deaton, Fei Mo, Maria Sverdlov, Peter H Gann, Saurabh Sinha, Sahil Sahni, Kun Wang, Kevin Van Bortle, Emad Tajkorshid, Wendy A Woodward, Wonhwa Cho, Erik R Nelson
Faculty, Staff and Student Publications
Breast and other solid tumors respond poorly to immune therapy. Myeloid cells (MCs) such as macrophages contribute to resistance. Established clinical evidence links cholesterol to cancer outcomes, with MC function being regulated by cholesterol metabolism. We screened MC-expressed regulators of cholesterol homeostasis linked to survival and identified the cholesterol efflux protein ABCA1. ABCA1 activity increases anticancer functions of macrophages: enhancing tumor infiltration, decreasing angiogenic potential, reducing efferocytosis, and improving support of CD8+ T cell activity. Mechanistically, different AKT isoforms are involved, through both PI3K-dependent and PI3K-independent mechanisms. Highlighting the clinical relevance of our findings are correlations between ABCA1 in macrophages …
Nf2 Loss Malignantly Transforms Human Pancreatic Acinar Cells And Enhances Cell Fitness Under Environmental Stress, Yi Xu, Michael H Nipper, Angel A Dominguez, Chenhui He, Francis E Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang
Nf2 Loss Malignantly Transforms Human Pancreatic Acinar Cells And Enhances Cell Fitness Under Environmental Stress, Yi Xu, Michael H Nipper, Angel A Dominguez, Chenhui He, Francis E Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang
Faculty, Staff and Student Publications
Pancreatic ductal adenocarcinoma (PDAC) occurs as a complex, multifaceted event driven by the interplay of tumor-permissive genetic mutations, the nature of the cellular origin, and microenvironmental stress. In this study, using primary human pancreatic acinar 3D organoids, we performed a CRISPR-KO screen targeting 199 potential tumor suppressors curated from clinical PDAC samples. Our data revealed significant enrichment of a list of candidate genes, with neurofibromatosis type 2 associated gene (NF2) emerging as the top target. Functional validation confirmed that loss of NF2 promoted the transition of PDAC to an invasive state, potentially through extracellular matrix modulation. NF2 inactivation …
Public Support For Alcohol-Control Policies And Political Ideology In The Us, Joël Fokom Domgue, Robert Yu, Ernest Hawk, Sanjay Shete
Public Support For Alcohol-Control Policies And Political Ideology In The Us, Joël Fokom Domgue, Robert Yu, Ernest Hawk, Sanjay Shete
Faculty, Staff and Student Publications
This cross-sectional study examines the role of US adults’ political affiliation, perception about alcohol use and cancer, and sociodemographic and behavioral factors in banning outdoor alcohol advertising and adding cancer warnings on alcohol containers.
Laboratory Evaluation Of Armie, A Portable Sps30-Based Low-Cost Sensor Node For Pm 2.5 Monitoring., Asbjørn Kloppenborg, Louise B Frederickson, Rasmus Ø Nielsen, Clive E Sabel, Tue Skallgaard, Jakob Löndahl, Jose G C Laurent, Torben Sigsgaard
Laboratory Evaluation Of Armie, A Portable Sps30-Based Low-Cost Sensor Node For Pm 2.5 Monitoring., Asbjørn Kloppenborg, Louise B Frederickson, Rasmus Ø Nielsen, Clive E Sabel, Tue Skallgaard, Jakob Löndahl, Jose G C Laurent, Torben Sigsgaard
School of Geography, Earth and Environmental Sciences
BACKGROUND: Low-cost particulate matter sensors have enabled new opportunities for exposure monitoring but require evaluation before application in epidemiological studies. This study assessed the performance of the SPS30 sensor integrated into the ARMIE portable monitoring sensor-node under controlled laboratory conditions.
METHODS: Sensors were co-located with two comparison instruments-the optical DustTrak photometer and the combined Scanning Mobility Particle Sizer (SMPS) and Aerodynamic Particle Sizer (APS)-across multiple aerosol sources, including candle burning, cooking, cigarette smoke, and clean air, under both regular and high-humidity conditions. Calibration performance was evaluated using leave-one-sensor-out and leave-one-source-out approaches.
RESULTS: The ARMIE node demonstrated strong agreement with the …
Person-Centered Care In Adult Auditory Rehabilitation: A Scoping Review, Marien Alet Graham, Nannette Nicholson, Rachel Glade, Sonja Delport, Faheema Mahomed-Asmail
Person-Centered Care In Adult Auditory Rehabilitation: A Scoping Review, Marien Alet Graham, Nannette Nicholson, Rachel Glade, Sonja Delport, Faheema Mahomed-Asmail
Communication Disorders and Occupational Therapy Faculty Publications and Presentations
Objective To scrutinise the efficacy of person-centered care (PCC) in enhancing outcomes for adults navigating hearing loss through a comprehensive examination of literature on PCC in auditory rehabilitation (AR). Design A scoping review was conducted following Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) reporting standards. A context framework guided the research question. Study Sample Structured searches across multiple databases identified 36 records which were categorised by research design, mapped by the first author's country, and depicted by number of publications per year. Six identified elements of PCC were anaylzed …
Upcycle Of Used Jute Sacks For Production Of Shoes And Bags As Fashion Accessories, Solomon Gausa Dr., Ruth Adumna Ahmed, Muhammad Sani Yahaya Dr., Dymphna Bakker-Edoh Dr
Upcycle Of Used Jute Sacks For Production Of Shoes And Bags As Fashion Accessories, Solomon Gausa Dr., Ruth Adumna Ahmed, Muhammad Sani Yahaya Dr., Dymphna Bakker-Edoh Dr
Jurnal Sosial Humaniora Terapan
The study aims to upcycle used jute sacks into fashion accessories for sub-Saharan Africa, particularly Nigeria. The approach employs innovative design techniques and manufacturing processes that improve both the aesthetic appeal and environmental impact of jute products. To achieve the study's objectives, a design and development research approach was used to support an iterative process. A structured interview guide collected data from fifteen respondents. The study used thematic analysis by coding both open and axial codes, which were selected and grouped according to the objective to reach the final results before interpreting and translating the findings into a developed design …
Nasionalisme Di Era Artificial Intelligence: Scoping Review, Mudita Vidyananda, Angelina Regina Halim, Patricia Irene, Muhammad Firliansyah Maliki, Ivana Suryaprawira, Bonar Hutapea
Nasionalisme Di Era Artificial Intelligence: Scoping Review, Mudita Vidyananda, Angelina Regina Halim, Patricia Irene, Muhammad Firliansyah Maliki, Ivana Suryaprawira, Bonar Hutapea
Jurnal Sosial Humaniora Terapan
This paper aims to map and thematically present the existing literature on the intersection of Artificial Intelligence (AI), identity, and AI Nationalism, following a scoping review approach. A systematic search was conducted across the Scopus, Web of Science, ACM Digital Library, and Google Scholar databases to identify relevant studies. The selected studies, published between 2020-2025, focus on the impact of AI on identity and geopolitics, resulting in six papers included in the final synthesis. The analyzed studies employed various methods, including conceptual, qualitative, quantitative, and mixed-methods approaches. Data extracted from each study included author, publication year, objectives, methodology, and key …
Pengujian High Fidelity Prototipe Media Pembelajaran Interaktif Bahasa Inggris Dengan Gamifikasi Menggunakan User Experience Questionare, Adhitya Prastyadi, Meizano Muhammad Ardhi, Daniel Rinaldi, Margaretha Karolina Sagala
Pengujian High Fidelity Prototipe Media Pembelajaran Interaktif Bahasa Inggris Dengan Gamifikasi Menggunakan User Experience Questionare, Adhitya Prastyadi, Meizano Muhammad Ardhi, Daniel Rinaldi, Margaretha Karolina Sagala
Jurnal Sosial Humaniora Terapan
Abstract
Testing a Hi-Fi Prototype of Interactive English Learning Media with Gamification Using UEQ
This study aims to test and evaluate the User Experience (UX) quality of a High-Fidelity prototype for interactive English learning media integrating gamification elements. The research is motivated by the low English proficiency and motivation among Indonesian students, and the potential of digital media and gamification to enhance learning engagement. Inspired by the success of the Duolingo application, this prototype was designed to create an enjoyable and effective learning experience. A quantitative research methodology was employed, involving high school students as participants selected via purposive sampling. …
When You Can't Get A One-Shot, Try A One Off, Chereeka Garner, Katy Miller, Renee Cole Montgomery
When You Can't Get A One-Shot, Try A One Off, Chereeka Garner, Katy Miller, Renee Cole Montgomery
Georgia International Conference on Information Literacy
One of the challenges facing librarians is getting exposure to students to teach information literacy skills. Faculty engagement with the library can vary greatly, with many faculty simply not having available class time to allow librarians in the classroom. As a possible alternative means of connecting with students, an Extra Credit Hub was created. This hub is an easily located, visible resource for faculty to share potential extra credit activities with students.
The Hub, which is a standalone Canvas course, includes a number of activities related to key information literacy skills, such as:
- Recognizing bias, misinformation, and disinformation
- Critical thinking …
The Gsa Leadership Committee: Collective Liberation Through Community Building In Chicago Public Schools, Elizabeth A. Jarpe-Ratner, Corey M. Blake, Emilie L. Clark, Li Lichner, Meaghan L. Tomasiewicz, Nora Benomar, Jose Dominguez Magdaleno, Booker Marshall, Makayla Boyd, D. Little
The Gsa Leadership Committee: Collective Liberation Through Community Building In Chicago Public Schools, Elizabeth A. Jarpe-Ratner, Corey M. Blake, Emilie L. Clark, Li Lichner, Meaghan L. Tomasiewicz, Nora Benomar, Jose Dominguez Magdaleno, Booker Marshall, Makayla Boyd, D. Little
Journal of Queer and Trans Studies in Education
Strong evidence links Gender and Sexuality Alliances (GSAs) to improved outcomes for LGBTQ+ (lesbian, gay, bisexual, queer and questioning and other identities) students. Chicago Public Schools’ (CPS) is known for being a leader in supporting LGBTQ+ students. Despite this, CPS’ size has made it difficult to support all schools in adopting recommended practices. Therefore, in 2020 CPS launched the GSA Leadership Committee (GSALC), which comprises teachers and other school-based staff leaders throughout the district, to support all schools in adopting practices known to support LGBTQ+ students. This paper draws on four years of interviews with group facilitators and focus groups …
Ai In Society: A Regulatory Framework For Responsible Integration, Ziad Doughan, Sari Itani, Hadi Al Mubasher
Ai In Society: A Regulatory Framework For Responsible Integration, Ziad Doughan, Sari Itani, Hadi Al Mubasher
BAU Journal - Science and Technology
This review paper studies the influence of Artificial Intelligence (AI) and Machine Learning (ML) on society in various categories in detail. AI and ML have developed rapidly in the past two decades, thus changing our lifestyles. These developments have various positive and negative impacts on society. This paper explores the many societal impacts of AI and ML, in economics, social aspects, ethics, and policy, shedding light on the opportunities and challenges that arise. An interdisciplinary insight is capable of understanding the challenges society faces when it uses AI and ML, locking opportunities that lie ahead and identifying promising paths towards …
Making Sense: Envy In Libanius' Declamation 30, Andrew Scholtz
Making Sense: Envy In Libanius' Declamation 30, Andrew Scholtz
Middle Eastern and Ancient Mediterranean Studies (MEAMS) Faculty Scholarship
Declamation, a genre famous for its sometimes extravagant fictions, has lately been approached as a vehicle for declaimers to reflect on realities familiar to them and their audiences. Reading Libanius' rarely discussed Declamation 30 in just such a self-reflective key, I argue that it explores the mindset of the phthoneros, the "envious man," as a way to make sense of risks posed by unscrupulous rivals. To shed light on this sense-making, I analyze High- and Late-Imperial emotion scripts foregrounding envy’s power to catalyze the formation of dysfunctional networks within and around competitive situations.
Pacs Viewbook 2026-2027, Program In Audiology And Communication Sciences
Pacs Viewbook 2026-2027, Program In Audiology And Communication Sciences
PACS News
No abstract provided.
Psychotherapy Technique And Emotional Communication: The Relationship Between Technique Use In Psychotherapy And Patient Speech Styles Associated With The Referential Process, Sorrel Johnson M.S.
Psychotherapy Technique And Emotional Communication: The Relationship Between Technique Use In Psychotherapy And Patient Speech Styles Associated With The Referential Process, Sorrel Johnson M.S.
Selected Full Text Dissertations, 2011-
Linguistic analysis is a growing field within psychotherapy process research. Computerized measures have been developed to quantify qualities of speech associated with the Referential Process (RP), a construct describing the way in which people communicate emotional experience by cycling through different language styles (Bucci, 2021c). The three phases of RP are arousal, referential activity (RA), and reflection/reorganizing (R/R). Examining the latter two, the current study aimed to determine if therapists’ use of techniques was associated with immediate levels of patient RA and R/R in a sample of three archival psychotherapy sessions. Sessions were coded moment-by-moment (N=263 therapist speech turns) for …
Physiologically Based Pharmacokinetic Modeling Of Acetaminophen In A Preterm Neonate Population, Sonia Sharma
Physiologically Based Pharmacokinetic Modeling Of Acetaminophen In A Preterm Neonate Population, Sonia Sharma
Selected Full-Text Dissertations 2020-
Extremely preterm neonates are a pharmacologically vulnerable group due to their immature organ function and rapid developmental changes, which complicate optimal drug dosing. This thesis introduces a comprehensive physiologically based pharmacokinetic (PBPK) model for acetaminophen (APAP) tailored to this population, incorporating mechanistic ontogeny equations for key sulfotransferase (SULT) enzymes SULT1A1, SULT1A3, SULT1B1, and SULT2A1 developed from a unique dataset of pediatric liver samples. The PBPK model was calibrated and validated using observed pharmacokinetic data from neonates, infants, and children, demonstrating high predictive accuracy across developmental stages. By applying virtual twin simulations, the model was used on a nationwide children's hospital …