Digital Commons Network^™

Occupational Therapy’S Role In Emergency And Disaster Preparation For The Population Of Physically Disabled Individuals, Aldin Cerillo, Susan Macdermott, Karen Park

Fall 2021 Virtual OTD Capstone Symposium

Emergencies and disasters may occur anywhere in the world, with no population immune to their effects. Vulnerable populations, including individuals with physical disabilities, are more at risk and lose the ability to maintain crucial occupations in the event of an emergency or disaster (Rutkow et al., 2015). Currently occupational therapy services have a strong presence in post emergency situations, in a recovery capacity. Despite Safety and Emergency Maintenance being an Instrumental Activity of Daily Living, a gap exists in the literature regarding what occupational therapists may do when engaging in emergency and disaster preparation with individuals who have a physical …

The Impact Of Culture On Family-Centered Care, Summer Akbar, Susan Macdermott, Karen Park

Fall 2021 Virtual OTD Capstone Symposium

Consistent caregiver involvement in therapy services is a necessity for an increase in therapeutic outcomes for children and caregiver confidence. A caregiver’s cultural background plays a significant role in choices made on behalf of their child and the amount of caregiver engagement that is involved in their child’s therapy services. When cultural factors and needs are unacknowledged or unmet by therapists, this can lead to a decrease in motivation for caregivers and their children to participate in therapeutic interventions. Due to the essential need for a caregiver to be involved in their child’s pediatric therapy services, pediatric OTs must learn …

An Educational Website To Foster The Participation Of Summer Campers With Disabilities, Abby Vander Laan, Steven M. Gerardi

Fall 2021 Virtual OTD Capstone Symposium

ABSTRACT NEEDED

Providing Care To People With Dementia: An Educational Workshop, Hannah Hardeman, Steven M. Gerardi, Emily Frank

Fall 2021 Virtual OTD Capstone Symposium

Informal (family) caregivers providing care to loved ones experiencing symptoms of dementia and Alzheimer’s Disease navigate multiple challenges. Caregivers observe and respond to changes in their loved ones related to physical, emotional and social skills. While providing care to their loved ones, caregivers must be aware of their own needs and the importance of maintaining a balance between the responsibilities of being a caregiver and the responsibilities in other areas of their life. Maintenance of positive emotional and physical health is crucial to providing effective and safe care. Identification of methods to promote the positive health of informal caregivers becomes …

Cyanobacteria And Phytoplankton Responses To Nutrients In Deep-Water Montane Reservoirs, Madeleine Paige Malmfeldt

Theses and Dissertations

Mountains play an important role in providing water resources from snow and ice to downstream urban population centers. In Utah, USA, nearly 86% of the state's population resides in the rapidly growing urban corridor along the Wasatch Front. Water along the Wasatch Front is stored in several deep reservoirs in the Provo River Watershed. Additions of nutrients, into these reservoirs, may stimulate the growth of primary producers (e.g., total phytoplankton and cyanobacteria) potentially attenuating water quality. To determine the influence of nutrients on primary producers in the Provo River's reservoirs, identify whether cyanobacteria are transported downstream, and quantify nutrient thresholds …

Evidence Of Myomir Regulation Of The Pentose Phosphate Pathway During Mechanical Load-Induced Hypertrophy, Taylor Valentino, Vandre C. Figueiredo, C. Brooks Mobley, John J. Mccarthy, Ivan J. Vechetti Jr.

Physiology Faculty Publications

Many of the molecular and cellular mechanisms discovered to regulate skeletal muscle hypertrophy were first identified using the rodent synergist ablation model. This model reveals the intrinsic capability and necessary pathways of skeletal muscle growth in response to mechanical overload (MOV). Reminiscent of the rapid cellular growth observed with cancer, we hypothesized that in response to MOV, skeletal muscle would undergo metabolic programming to sustain increased demands to support hypertrophy. To test this hypothesis, we analyzed the gene expression of specific metabolic pathways taken from transcriptomic microarray data of a MOV time course. We found an upregulation of genes involved …

Medicines Regulation In West Africa: Current State And Opportu-Nities, Oluwafunmike Sopein-Mann, Z Ekeocha, S Byrn, K Clase

BIRS Africa Technical Report Papers

Ndomondo-Sigonda et al. (2017) observed that there is scarcity of information on human resources (person-nel devoted to regulation of medicines) in the domain of medicines regulation in the sub-Saharan Africa (SSA). The published information on medicines regulation by the National Medicines Regulatory Authorities (NMRAs) in the Economic Community of West African States (ECOWAS) region are no longer current and consistent with the current realities in the NMRAs. In order to reveal this occurrence, show the trends that exist over the years and make appropriate recommendations, data were collected and compared from 2005, 2010 and 2017 research reports on seven regulatory …

Quality Of Sample Testing In The Laboratory Unit: Current Situation And Strategies For Improvement, Aloyce Constantine, Z Ekeocha, S Byrn, K Clase

BIRS Africa Technical Report Papers

The purpose of this study was to understand the status quo of quality sample testing in the laboratory unit. A quantitative research method was used. An extensive laboratory documents (protocol, worksheets, laboratory analytical plan, standard operating procedures and manuals) review was performed and a networking approach to both management and lab staff at all levels was reviewed in order to identify all non-conformities occurred in the past three years. Results identified 36 number of results deviated from reference standards among different test performed, 400 number of samples lost, the number of laboratory personnel who were not sufficiently trained to take …

The Impact Of Mentoring As A Gmp Capability Building Tool In The Pharmaceutical Manufacturing Industry In Nigeria, Monica Agu, Z Ekeocha, S Byrn, K Clase

BIRS Africa Technical Report Papers

Good Manufacturing Practices (GMP), a component of Pharmaceutical Quality Systems, is aimed primarily at managing and minimizing the risks inherent in pharmaceutical manufacture to ensure the quality, safety and efficacy of products. Provision of adequate number of personnel with the necessary qualifications/practical experience and their continuous training and evaluation of effectiveness of the training is the responsibility of the manufacturer. (World Health Organization [WHO], 2014; International Organization for Standardization [ISO], 2015). The classroom method of training that has been used for GMP capacity building in the pharmaceutical manufacturing industry in Nigeria over the years, delivered by experts from stringently regulated …

Retrospective Study Of Inspectors Competency In The Act Of Writing Gmp Inspection Report, Chidi Uche, Z Ekeocha, S Byrn, K Clase

BIRS Africa Technical Report Papers

The research was a retrospective study of twenty-five Good Manufacturing Practice (GMP) inspection reports (from March 2017 through to December 2018) of a national medicine regulatory agency, drug Inspectorate, in West Africa, designed to assess the inspectors’ expertise in the act of inspection report writing. The investigation examined a paper-based tool of thirteen pre-registration Inspection reports and twelve GMP reassessment reports written prior and following an intervention program by external GMP trainers to enhance inspectors’ skill in pharmaceutical cGMP inspection. The study made use of quantitative analysis to investigate each team’s expertise in the act of writing GMP inspection report. …

The Montclarion, December 9, 2021, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Strategies For Teaching Based On Autism Research (Star Program) Curriculum Review And Implementation, Cassidy Harrington

Dissertations, Theses, and Projects

Autism Spectrum Disorder (ASD) is becoming more prevalent in school systems. Researchers began tracking the prevalence of ASD in the year 2000. It is estimated that 1 in 68 children have ASD in the United States of America (1 in 42 prevalence for boys and 1 in 189 prevalence for girls) (Landa, 2018). Medically a child can be diagnosed with ASD but school systems themselves are not able to formally diagnose ASD in children. (ECTA, 2012). ASD can be hard to diagnose as some cases are more severe than others and the earlier that a child is found to have …

Co-Teaching: How And Where To Begin In A Middle School, Janaya Fugleberg

Dissertations, Theses, and Projects

In 2004 the Individuals Education with Disabilities Act (IDEA) provided a directive that public agencies needed to educate children with disabilities alongside children who do not have a disability. This needed to occur in the least restrictive environment possible. The purpose of this was to allow students with disabilities to be in the general education classroom as much as possible because when students are pulled out of class they are missing academics and social opportunities with their peers. Co-teaching is an instructional strategy that allows for students with disabilities to stay in their classroom while still receiving the support they …

The Impact Of Small Group Direct Instruction On The Vocabulary Development Of Fourth Grade Students, Rachel Solum

Dissertations, Theses, and Projects

This 2021 study focused on the impact that small group vocabulary instruction had on the vocabulary development of 4th grade students. I wanted to see the effect that small group instruction had on students’ vocabulary growth. Students were pulled into a small group every day for four straight weeks. There was four groups of four students involved. During this small group time the teacher pulled vocabulary words from the word wall. The words on the word wall were tier two vocabulary words that had been pulled from various interactive read alouds. The teacher followed Marzano’s Six Step Approach to teaching …

Self-Efficacy: Nurses’ Perceptions Of Caring For Patients Living With Diabetes, Victoria Y. Mccue

Nursing & Health Sciences Research Journal

Introduction: Diabetes is an epidemic that affects over 415 million people worldwide. In the United States, the number of people diagnosed with diabetes is projected to triple to over 60 million by 2060. With this surge, the number of hospitalizations across the country has significantly increased. Direct care nurses play a vital role in the management of patients living with diabetes. The purpose of this research study was to explore and describe medical-surgical nurses’ perceptions of self-efficacy related to caring for patients living with diabetes. This study's guiding research question was: What are nurses’ perceptions on the influences that impact …

Overcoming Undergraduate Nursing Education Challenges During The Pandemic, Melissa Abreu, Carolina Ferreiro, Danielle Garcia, Gisell Gonzalvo, Erika Nusbaum, Beatrice Sikah

Nursing & Health Sciences Research Journal

Despite the challenges encountered throughout the COVID-19 pandemic, undergraduate nursing education was able to pivot and prevent cessation as faculty and students utilized various virtual platforms to provide didactic, skills lab, and clinical exposure without delaying graduation for many students. Although nothing could replace the hands-on human interaction a clinical rotation provided, virtual experiences aligned with the course content helped students reinforce the concepts taught in the corresponding didactic portion proving this to be beneficial in its own way. As faculty, we rose to the challenge in fostering a supportive environment to keep students motivated to learn and engaged in …

Coping In Pediatric Burn Survivors And Its Relation To Social Functioning And Self-Concept, Mira D H Snider, Sarah Young, Paul T Enlow, Corrine Ahrabi-Nejad, Ariel M Aballay, Christina L Duncan

Department of Pediatrics Faculty Papers

Pediatric burn survivors experience increased risk for bullying, stigmatization, body image concerns, and problematic social functioning. Although coping behaviors are associated with engagement in social supports and positive self-concept in multiple pediatric illness populations, their relation has not been examined in pediatric burns. This study examined coping in relation to social functioning and self-concept in 51 pediatric burn survivors aged 7–17years (M=12.54; SD=2.65). Survivors and their caregivers completed the Child Coping Strategies Checklist (CCSC; youth report); the Burn Injury Social Questionnaire (BISQ; parent and youth report); and the Piers-Harris Children’s Self-Concept Scale-2 (PH-2; youth report). Associations between coping, social functioning, …

Barriers Of Bronson School Of Nursing Program, Karla Kline

Honors Theses

Aside from the rigorous coursework of nursing school, nursing students experience various barriers that impact their academic success. Barriers to successful completion of traditional Bachelor of Science of Nursing (BSN) programs include isolation, lack of peer connections, lack of faculty connections, lack of family support, lack of financial support, and mental health struggles (Shaw, 2015) (Seal & Woods, 2021). This research will aim at assessing and exploring these barriers students are facing, along with the additional or exacerbated barriers the COVID-19 pandemic has surfaced.

This study will expand on the research conducted by Shaw (2015), in which she examined the …

Autonomous Control And Signal Acquisition System, Rion Cadell Krampe

Honors College Theses

Our goal is to continue a previous teams project to build a NDE autonomous control and signal acquisition system that is more precise, more customizable with both code and mechanical parts, and cheaper than a similar system bought by the school. This goal has two stages to it. First, to repair the system from considerable damage it received during transportation. Secondly, to continue designing and developing the system to make considerable progress towards the goal of a fully functional NDE system. Along with making progress we must consider the team after us and create an easy stepping off point for …

The Cowl - V. 86 N. 10 - Dec 9, 2021

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 10 - December 9, 2021. 40 pages.

Understanding Factors Influencing Seed Germination Of Seven Wildflowers In Sub-Alpine Ecosystems, Alyssa Joy Brown

Theses and Dissertations

This thesis explores the seed germination of seven wildflowers native to sub-alpine ecosystems. Wildflowers are an essential functional group in native plant ecosystems. Also known as forbs, these plants offer a myriad of benefits in addition to being aesthetically pleasing. They provide habitats for anthropods and small mammals, support native pollinator populations, and grow well with other plant functional groups (especially perennial grasses and shrubs). Healthy plant communities make use of the limited resources in our native ecosystems, competing with invasive species that can otherwise dominate the landscape. Germination involves the transition from seed to an actively growing plant. Following …

At-Sensor Radiometric Correction Of A Multispectral Camera (Rededge) For Suas Vegetation Mapping, Cuizhen Wang

Faculty Publications

Rapid advancement of drone technology enables small unmanned aircraft systems (sUAS) for quantitative applications in public and private sectors. The drone-mounted 5-band MicaSense RedEdge cameras, for example, have been popularly adopted in the agroindustry for assessment of crop healthiness. The camera extracts surface reflectance by referring to a pre-calibrated reflectance panel (CRP). This study tests the performance of a Matrace100/RedEdge-M camera in extracting surface reflectance orthoimages. Exploring multiple flights and field experiments, an at-sensor radiometric correction model was developed that integrated the default CRP and a Downwelling Light Sensor (DLS). Results at three vegetated sites reveal that the current CRP-only …

The Effect Of Volunteering On Philanthropic Giving To American Higher Education, Jess Metzmeier

Graduate Theses, Dissertations, and Capstones

To explore the effect of volunteering on philanthropic giving to U.S. higher education, the study considered the giving rates of first-time alumni participants in an alumni-student career mentor program as measured over three periods: the year prior to their first year as a mentor, their first year as a mentor, and the year following their first year as a mentor. Using a repeated measure ANOVA statistical method, the study sought to determine if there is a statistically significant variance in the giving rates of these volunteers across the three measures. The study also explored the influence of a participant’s prior …

A Performance Improvement Project To Improve Hand-Off Communication Documentation Within The Surgical Services Department, Bobbie J. Wich, Millie Escalona, Judy E. Bowling, Ana L. Santos

Nursing & Health Sciences Research Journal

Over 80% of adverse events in healthcare are due to miscommunication. To improve patient safety, The Joint Commission recommended the use of standardized hand-off communication tools in 2012. One acute care hospital in Southeast Florida implemented standardized handoff reports in 2014 with few revisions since that time. The COVID-19 pandemic brought to light additional critical information was needed to keep patients and staff safe, such as laboratory results indicating the need for isolation precautions. The nurses within the surgical services noticed this critical information was not sufficiently included in the handoff report. The lack of this information led to unnecessary …

A Nursing Leader’S Perspective In Preparing For Magnet® Redesignation In The Midst Of The Covid-19 Pandemic, Harold Girado

Nursing & Health Sciences Research Journal

No abstract provided.

Meta-Analyses Identify Dna Methylation Associated With Kidney Function And Damage, Pascal Schlosser, Adrienne Tin, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Antoine Weihs, Zhi Yu, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Monique M B Breteler, Cristian Carmeli, Layal Chaker, John C Chambers, Shelley A Cole, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Niek De Klein, Graciela E Delgado, Arce Domingo-Relloso, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, Kathryn L Evans, James S Floyd, Myriam Fornage, Lude Franke, Eliza Fraszczyk, Xu Gao, Xīn Gào, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Marjo-Riitta Jarvelin, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Holly Kramer, Florian Kronenberg, Brigitte Kühnel, Terho Lehtimäki, Lars Lind, Dan Liu, Yongmei Liu, Donald M Lloyd-Jones, Kurt Lohman, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Ana Navas-Acien, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Sylvia E Rosas, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Maria Tellez-Plaza, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Niek Verweij, Rosie M Walker, Matthias Wielscher, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Daniel Levy, Melanie Waldenberger, Katalin Susztak, Anna Köttgen, Alexander Teumer

Faculty, Staff and Student Publications

Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. to extend the knowledge on regulatory mechanisms related to kidney function and disease, we conducted a blood-based epigenome-wide association study for estimated glomerular filtration rate (n = 33,605) and urinary albumin-to-creatinine ratio (n = 15,068) and detected 69 and seven CpG sites where DNA methylation was associated with the respective trait. The majority of these findings showed directionally consistent associations with the respective clinical outcomes chronic kidney disease and moderately increased albuminuria. …

Exploratory Study Of Nursing Leadership: An Inquiry Of Leadership Attributes Of Nurse Managers In Acute Care Hospitals And The Professional Practice Environment, Janet Henriksen

Dissertations

This study explored the perceived leadership attributes of nurse managers who enable the creation of positive professional practice environments for registered nurses in acute care hospitals. A general qualitative approach was used to explore the perceptions of ten acute care registered nurses using a three-interview method of inquiry. Three major categories emerged from the data analysis: nurse manager attributes, positive professional practice environment characteristics, and nurse retention, recruitment and job satisfaction. Eight themes emerged in the nurse manager attributes category: expert, mentor, participant, communicator/listener, problem-solver/critical thinker, supporter, arbitrator, and advocate. Seven themes emerged in the characteristics of a positive professional …

Epigenome-Wide Association Study Of Serum Urate Reveals Insights Into Urate Co-Regulation And The Slc2a9 Locus, Adrienne Tin, Pascal Schlosser, Pamela R Matias-Garcia, Chris H L Thio, Roby Joehanes, Hongbo Liu, Zhi Yu, Antoine Weihs, Anselm Hoppmann, Franziska Grundner-Culemann, Josine L Min, Victoria L Halperin Kuhns, Adebowale A Adeyemo, Charles Agyemang, Johan Ärnlöv, Nasir A Aziz, Andrea Baccarelli, Murielle Bochud, Hermann Brenner, Jan Bressler, Monique M B Breteler, Cristian Carmeli, Layal Chaker, Josef Coresh, Tanguy Corre, Adolfo Correa, Simon R Cox, Graciela E Delgado, Kai-Uwe Eckardt, Arif B Ekici, Karlhans Endlich, James S Floyd, Eliza Fraszczyk, Xu Gao, Xīn Gào, Allan C Gelber, Mohsen Ghanbari, Sahar Ghasemi, Christian Gieger, Philip Greenland, Megan L Grove, Sarah E Harris, Gibran Hemani, Peter Henneman, Christian Herder, Steve Horvath, Lifang Hou, Mikko A Hurme, Shih-Jen Hwang, Sharon L R Kardia, Silva Kasela, Marcus E Kleber, Wolfgang Koenig, Jaspal S Kooner, Florian Kronenberg, Brigitte Kühnel, Christine Ladd-Acosta, Terho Lehtimäki, Lars Lind, Dan Liu, Donald M Lloyd-Jones, Stefan Lorkowski, Ake T Lu, Riccardo E Marioni, Winfried März, Daniel L Mccartney, Karlijn A C Meeks, Lili Milani, Pashupati P Mishra, Matthias Nauck, Christoph Nowak, Annette Peters, Holger Prokisch, Bruce M Psaty, Olli T Raitakari, Scott M Ratliff, Alex P Reiner, Ben Schöttker, Joel Schwartz, Sanaz Sedaghat, Jennifer A Smith, Nona Sotoodehnia, Hannah R Stocker, Silvia Stringhini, Johan Sundström, Brenton R Swenson, Joyce B J Van Meurs, Jana V Van Vliet-Ostaptchouk, Andrea Venema, Uwe Völker, Juliane Winkelmann, Bruce H R Wolffenbuttel, Wei Zhao, Yinan Zheng, Marie Loh, Harold Snieder, Melanie Waldenberger, Daniel Levy, Shreeram Akilesh, Owen M Woodward, Katalin Susztak, Alexander Teumer, Anna Köttgen

Faculty, Staff and Student Publications

Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. DNA methylation in whole blood captures genetic and environmental influences and is assessed in transethnic meta-analysis of epigenome-wide association studies (EWAS) of serum urate (discovery, n = 12,474, replication, n = 5522). The 100 replicated, epigenome-wide significant (p < 1.1E-7) CpGs explain 11.6% of the serum urate variance. At SLC2A9, the serum urate locus with the largest effect in genome-wide association studies (GWAS), five CpGs are associated with SLC2A9 gene expression. Four CpGs at SLC2A9 have significant causal effects on serum urate levels and/or gout, and two of these partly mediate the effects of urate-associated GWAS variants. In other genes, including SLC7A11 and PHGDH, 17 urate-associated CpGs are associated with conditions defining metabolic syndrome, suggesting that these CpGs may represent a blood DNA methylation signature of cardiometabolic risk factors. This study demonstrates that EWAS can provide new insights into GWAS loci and the correlation of serum urate with other complex traits.

Hedgehog-Interacting Protein Is A Multimodal Antagonist Of Hedgehog Signalling, Samuel C Griffiths, Rebekka A Schwab, Kamel El Omari, Benjamin Bishop, Ellen J Iverson, Tomas Malinauskas, Ramin Dubey, Mingxing Qian, Douglas F Covey, Robert J C Gilbert, Rajat Rohatgi, Christian Siebold

Open Access Publications

Hedgehog (HH) morphogen signalling, crucial for cell growth and tissue patterning in animals, is initiated by the binding of dually lipidated HH ligands to cell surface receptors. Hedgehog-Interacting Protein (HHIP), the only reported secreted inhibitor of Sonic Hedgehog (SHH) signalling, binds directly to SHH with high nanomolar affinity, sequestering SHH. Here, we report the structure of the HHIP N-terminal domain (HHIP-N) in complex with a glycosaminoglycan (GAG). HHIP-N displays a unique bipartite fold with a GAG-binding domain alongside a Cysteine Rich Domain (CRD). We show that HHIP-N is required to convey full HHIP inhibitory function, likely by interacting with the …

Lyl-1 Regulates Primitive Macrophages And Microglia Development, Shoutang Wang, Deshan Ren, Brahim Arkoun, Anna-Lila Kaushik, Gabriel Matherat, Yann Lécluse, Dominik Filipp, William Vainchenker, Hana Raslova, Isabelle Plo, Isabelle Godin

Open Access Publications

During ontogeny, macrophage populations emerge in the Yolk Sac (YS) via two distinct progenitor waves, prior to hematopoietic stem cell development. Macrophage progenitors from the primitive/"early EMP" and transient-definitive/"late EMP" waves both contribute to various resident primitive macrophage populations in the developing embryonic organs. Identifying factors that modulates early stages of macrophage progenitor development may lead to a better understanding of defective function of specific resident macrophage subsets. Here we show that YS primitive macrophage progenitors express Lyl-1, a bHLH transcription factor related to SCL/Tal-1. Transcriptomic analysis of YS macrophage progenitors indicate that primitive macrophage progenitors present at embryonic day …