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Performance Analysis Of Jpeg Xr With Deep Learning-Based Image Super-Resolution, Taingliv Min Jan 2022

Performance Analysis Of Jpeg Xr With Deep Learning-Based Image Super-Resolution, Taingliv Min

Chulalongkorn University Theses and Dissertations (Chula ETD)

The demand for efficient high-level image and video codec compression has widely increased. Conventional image compression methods such as JPEG XR use a high quantization parameter (QP) to produce a highly compressed file for any given image. However, higher QP has unpleasing artifacts that lead to perceptual quality degradation. A feasible solution to tackle this limitation is to reduce the high-resolution image size by downsampling it before encoding it with JPEG XR. Then, the super-resolution algorithm is applied to the resultant low-resolution image to reconstruct the high-resolution result. In this research, we downsample the input image before JPEG XR. Then, …

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Deep Consecutive Attention Network For Video Super-Resolution, Talha Saleem Jan 2022

Deep Consecutive Attention Network For Video Super-Resolution, Talha Saleem

Chulalongkorn University Theses and Dissertations (Chula ETD)

In the video application, slow motion is visually attractive and gets more attention in video super resolution. To generate the high-resolution (HR) slow motion video frames from the low-resolution (LR) frames, two sub-tasks are required, including video super-resolution (VSR) and video frame interpolation (VFI). However, the interpolation approach is not successful to extract low level feature attention to get the maximum advantage from the property of space-time relation. To this extent, we propose a deep consecutive attention network-based method. The multi-head attention and an attentive temporal feature module are designed to achieve better prediction of interpolation feature frame. Bi-directional deformable …

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Applications Of Deep Learning Framework And Localization To Intelligent Radio Spectrum Monitoring, Truong Thanh Le Jan 2022

Applications Of Deep Learning Framework And Localization To Intelligent Radio Spectrum Monitoring, Truong Thanh Le

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this thesis, the author proposed an intelligent radio spectrum monitoring system with implemented deep learning framework. Deep learning is a powerful method to handle hard tasks automatically. The system uses the RTL-SDR USB dongle as the sensor to collect the spectrum data. This dongle is a low-cost device that can measure the signal from 500kHz to 1700MHz. The maximum bandwidth of measurement is 2MHz. The main functions of this system are to collect the spectrum data and then detect the representation signals and extract their characteristics, such as bandwidth, center frequency, modulation type, and capacity. The modulation classification task …

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Functional Split In 5g Cloud Radio Access Network Using Particle Swarm Optimization, Wai Phyo Jan 2022

Functional Split In 5g Cloud Radio Access Network Using Particle Swarm Optimization, Wai Phyo

Chulalongkorn University Theses and Dissertations (Chula ETD)

The Cloud Radio Access Network (C-RAN) is an innovative approach that has the potential to significantly reduce the expenses of setting up and operating wireless networks. C-RAN's placement of RAN functions, which strives to reduce bandwidth utilization and computation costs, is a critical component. In this study, our main goal is to reduce the costs associated with functionally placing the RAN while accounting for the computational expense and the front-haul bandwidth usage among various users. To achieve this, we propose to apply Particle Swarm Optimization (PSO) to achieve effective allocation of computational resources and the front-haul bandwidth, ensuring an efficient …

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Online Self-Learning System For Prediabetes Patients, Ye Moe Myint Jan 2022

Online Self-Learning System For Prediabetes Patients, Ye Moe Myint

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis implements a web-based application that combines a 3D learning center and educational game to facilitate the monitoring, management, and treatment of patients with prediabetes mellitus, by providing exercise plans and controlled diets. The application utilizes advanced web technologies, 3D modeling, and gamification principles to create an engaging learning experience. User-centered design ensures usability, and testing demonstrates positive outcomes, including increased knowledge, motivation, and engagement. This research contributes to digital health interventions by empowering prediabetes patients with informed decision-making and healthy habits. Future directions include expanding the application, refining the user interface, and evaluating long-term impact on prediabetes management.

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Critical Success Factors For Data Warehouse Implementation In An Industrial Associations Organization, Phatnarin Khantayana Jan 2022

Critical Success Factors For Data Warehouse Implementation In An Industrial Associations Organization, Phatnarin Khantayana

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this research is to delve into the key success factors (CSFs) associated with data warehouse (DW) implementation from the perspectives of various stakeholders within an organization. A data warehouse provides a unified and structured view of an organization's data for analysis and reporting, and successfully implementing such a system can have a significant impact on overall organizational performance. It enables better data management, facilitates improved decision-making, and enhances strategic planning. The scope of this research encompasses an in-depth examination of the core CSFs that are instrumental in achieving success during data warehouse deployments. It focuses on understanding …

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Demand Forecasting And Inventory Management For An Automotive Tire Distributor In Northeast Thailand, Vasinee Chantaraponpun Jan 2022

Demand Forecasting And Inventory Management For An Automotive Tire Distributor In Northeast Thailand, Vasinee Chantaraponpun

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this research is to improve the inventory management for an automotive tire distributor company in Northeast Thailand to mainly reduce the excessive unnecessary stock. According to the initial investigations, the main causes of overstock are unstable customer demands and a lack of an inventory control system based on theory. In order to better address the issues and scope down the research area, three suitable products and sub-dealers with different demand patterns are selected to find the best-fit forecasting model for each of them and be customized the inventory policy based on the demand patterns. The methodology is …

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An Implementation Of An Integrated Performance Assessment Module To Promote English Speaking Ability And Learning Engagement Of Undergraduate Students, Benjawan Plengkham Jan 2022

An Implementation Of An Integrated Performance Assessment Module To Promote English Speaking Ability And Learning Engagement Of Undergraduate Students, Benjawan Plengkham

Chulalongkorn University Theses and Dissertations (Chula ETD)

Integrating assessment with instruction has been a challenge for English language teachers, especially in English speaking courses. Therefore, it is crucial to incorporate instruction and assessment methodologies that can help enhance students’ speaking ability. The Integrated Performance Assessment (IPA), designed by the American Council on the Teaching of Foreign Languages (Adair-Hauck et al., 2015), is a cluster assessment consisting of three modes of communication, namely interpretive, interpersonal, and presentational, to seamlessly connect instruction and assessment as well as reflect how students use the language. This study was conducted to 1) investigate the effects of an IPA module on undergraduate students’ …

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Digital Reading On Eil Materials For Thai Undergraduate Students, Nopphanan Adungdejjaroon Jan 2022

Digital Reading On Eil Materials For Thai Undergraduate Students, Nopphanan Adungdejjaroon

Chulalongkorn University Theses and Dissertations (Chula ETD)

This exploratory study had two research objectives. First, it aimed to investigate digital reading on EIL materials for Thai undergraduate students and, second, explore students' perceptions towards digital reading on EIL materials. The study involved two hundred and ninety-nine undergraduate students enrolled in an aviation business management program. The EIL Digital Reading Questionnaire is to collect quantitative data, while the semi-structured interview is to collect qualitative data. The result from descriptive statistics of the questionnaire and thematic analysis of the semi-interview reported that Thai undergraduate students tended to encounter, engage, and evaluate EIL materials frequently. Most of the participants strongly …

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The Effects Of Peer Feedback And Self-Regulated Learning On Thai Efl University Students’ Essay Writing Ability And Self-Regulation, Jantra Prompan Jan 2022

The Effects Of Peer Feedback And Self-Regulated Learning On Thai Efl University Students’ Essay Writing Ability And Self-Regulation, Jantra Prompan

Chulalongkorn University Theses and Dissertations (Chula ETD)

The primary objective of this mixed-method study was to explore the effectiveness of integrating peer feedback and self-regulated learning (SRL) in improving students’ essay writing ability and self-regulation. The study also investigated the relationship between students’ essay writing ability and their self-regulation, as well as explored students’ attitudes towards the intervention. During the 12-week online instruction necessitated by the pandemic crisis, a group of thirty-five 3rd year students majoring in Business English at Nakhon Pathom Rajabhat University were instructed in essay writing using peer feedback activities and SRL techniques. Data collection involved an essay writing test, a self-regulation questionnaire, semi-structured …

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Effects Of The Writing Instructional Model With Integration Of Inquiry-Based Learning And Visual Literacy On 21st Century Skills Of Efl Learners, Patsawut Sukserm Jan 2022

Effects Of The Writing Instructional Model With Integration Of Inquiry-Based Learning And Visual Literacy On 21st Century Skills Of Efl Learners, Patsawut Sukserm

Chulalongkorn University Theses and Dissertations (Chula ETD)

Although a body of research illustrates the potential of inquiry-based learning in promoting the 21st century skills among English as a Foreign Language (EFL) students (AbuRezeq, 2018; Imansyan et al., 2019; Milatasari, 2013; Palupi et al., 2020; Tongjean et al., 2019), other studies have indicated its occasional failure in eliciting students’ engagement (Duschl & Wright, 1989; Gill, 2005), which affects students’ success in language learning. This results in the need to leverage other pedagogical strategies, including visual literacy, to increase the efficacy of inquiry-based learning (Gonzalez-Ledo, 2015; Maricimoi, 2017; Navidinia et al., 2018; Rokhaniyah, 2019, Sulastri, 2019; Tayib, 2015; Villasor, …

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A Study Of Students' Reading Engagement And Perception Of Eil Materials, Tayaporn Nakornsut Jan 2022

A Study Of Students' Reading Engagement And Perception Of Eil Materials, Tayaporn Nakornsut

Chulalongkorn University Theses and Dissertations (Chula ETD)

The popularity of English as an International Language has been rapidly growing, contributing EIL materials to have become more widespread in learning. This study discusses students’ reading engagement and their perception of EIL materials, which aims to (1) investigate students’ engagement in reading EIL materials, (2) explore student perception of EIL materials, and (3) explore the relationship between students’ level of reading engagement and their perception of EIL materials. 113 undergraduate students at one private college who use English as a medium for their instruction were participated in this study. A mixed-method study which Reading Engagement Questionnaire and EIL Perception …

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Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra Jan 2022

Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: This study evaluated the association among the dental arch form, age-sex groups, and sagittal root position regarding alveolar bone thickness in the maxillary central incisor using cone-beam computed tomography (CBCT) images. Materials and Methods: CBCT images of 280 patients were categorized based on the dental arch form and age-sex groups. Five hundred and sixty sagittal CBCT images of the maxillary central incisors were examined to measure the labial and palatal bone thickness at the root apex level, at the mid-root level and 3 mm apically from cemento-enamel junction, with SRP classification. Chi-square, Kruskal-Wallis test, and multiple linear regression were …

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Flow-Performance Relationship In Defi Yield Aggregator, Apisara Pornprasith Jan 2022

Flow-Performance Relationship In Defi Yield Aggregator, Apisara Pornprasith

Chulalongkorn University Theses and Dissertations (Chula ETD)

Decentralized Finance (DeFi) is a new financial infrastructure with applications similar to traditional financial products, such as exchange, lending, derivatives, and asset management. This paper empirically investigates Yearn finance, one of the fastest-growing and largest in DeFi yield aggregator protocols for on-chain asset management, to demonstrate the flow-performance relationship and compare it with mutual funds in traditional finance. According to the findings, there is a positive non-linear relationship between fund flows and recent performance for using stablecoin deposited. In contrast, we cannot find this relationship for using cryptocurrency. Then, we look further into stablecoin holder behaviour and our findings show …

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Development Of High Protein Beverage From Hydrolyzed Egg White, Nuntorn Charoensak Jan 2022

Development Of High Protein Beverage From Hydrolyzed Egg White, Nuntorn Charoensak

Chulalongkorn University Theses and Dissertations (Chula ETD)

The primary objective of this study was to examine the impact of enzymatic treatment on pasteurized egg white protein (EWP) and assess its influence on various physicochemical properties and antioxidant activity. Our findings revealed that the addition of SDAY10 enzymes led to a significant increase in lightness (L*), redness (a*), and yellowness (b*) parameters. Furthermore, higher concentrations of the enzyme resulted in a considerable reduction in pH, viscosity, and volume mean diameter (D4,3) of EWP protein compared to the control group (P < 0.05). Additionally, the application of SDAY10 enzyme (0.1-0.3% w/v) for EWP hydrolysis exhibited a noteworthy enhancement in antioxidant activity (measured by DPPH, ABTS, and FRAP assays) compared to lower enzyme concentrations. Notably, the 0.3% concentration of SDAY10 exhibited the highest release of amino acids during in vitro digestion and received the highest sensory evaluation score. Consequently, employing SDAY10 enzymes at a concentration of 0.3% w/v for EWP hydrolysis demonstrates significant potential for improving the physical properties of EWP and enhancing antioxidant activity. However, it is imperative to investigate the sensory evaluation with regards to the bitterness of the product developed using such enzymes.

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Factors Associated With Oral Health Status Among The Healthy Elderly In Phon Thong District, Roi Et Province, Thailand, Yaowapa Chantaraboot Jan 2022

Factors Associated With Oral Health Status Among The Healthy Elderly In Phon Thong District, Roi Et Province, Thailand, Yaowapa Chantaraboot

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: This study aimed to identify factors related to the oral health status of healthy elderly people in Phon Thong District, Roi Et Province, Thailand. Materials and methods: This cross-sectional study was conducted between 1 May and 25 December 2020 in Phon Thong District, Roi Et Province. A total of 249 male and female elderly people participated in the study. Oral health information was collected by trained dental hygienists using the Thai version of the oral health assessment tool [OHAT]. Data analysis used Mann–Whitney U tests, Chi-Square tests, and Binary logistic regression. Results: There were statistically significant associations between oral …

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The Potential Risk And Occupational Exposure Of Pesticides Among Rice Farmers In Delta Ayeyarwady Division, Myanmar, Moe Thu Khin Jan 2022

The Potential Risk And Occupational Exposure Of Pesticides Among Rice Farmers In Delta Ayeyarwady Division, Myanmar, Moe Thu Khin

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aims to assess the potential risk and occupational exposure of pesticides among rice farmers in the Delta Ayeyarwady Region, Myanmar. A cross-sectional study was carried out with 454 rice farmers from March-April 2022. Data collection was done through face-to-face interviews used with a semi-structured questionnaire. The study showed that the mean age of farmers was 44.36 years old while the range was 16 and 74 years old. Rice farmers' average weight (± standard deviation) was 56.86 (± 7.30) kg. In this study, over two-thirds of the rice farmers (77 %) had a moderate level of knowledge regarding environmental …

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Assessment Of Greenhouse Gases Emissions From Dairy Cattle Production In Thailand, Phoo Pwint Pwint Thu Jan 2022

Assessment Of Greenhouse Gases Emissions From Dairy Cattle Production In Thailand, Phoo Pwint Pwint Thu

Chulalongkorn University Theses and Dissertations (Chula ETD)

Thailand’s agriculture sector plays a vital role in driving economic growth. Globally, livestock production is estimated to contribute about 18% of greenhouse gas (GHG) emissions. Despite its importance, there is a relative lack of research on GHGs assessment in the livestock sector in Thailand. The aim of this research was to estimate GHGs emissions from dairy cattle production in Saraburi and Ratchaburi provinces of Thailand. The 2019 Refinement to the 2006 IPCC guidelines for national greenhouse gas inventories was applied in this research. Twenty dairy farms (n=20) including both small farms (n=10) and medium farms (n=10) were selected as the …

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Southeast Asian Ministers Of Education Organization (Seameo) 'S Role In Digitalisation For Vocational Education Development : A Comparative Analysis Of Indonesia And Thailand, Anastasia Sylvia Jan 2022

Southeast Asian Ministers Of Education Organization (Seameo) 'S Role In Digitalisation For Vocational Education Development : A Comparative Analysis Of Indonesia And Thailand, Anastasia Sylvia

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis focuses on the role of the SEAMEO (Southeast Asian Ministers of Education Organization) role in vocational education development in Industry 4.0. Nowadays, there is a demand for the education sector to align with Industry 4.0, known as Education 4.0. In 2018, the SEAMEO, in collaboration with the GIZ, launched a Regional In-Service Training Modules project to support vocational education for Education 4.0. This study compares the impact of the Regional In-Service Training Modules project in two countries with a medium level of education performance in Southeast Asia: Indonesia and Thailand. This study employs a qualitative method with a …

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Unpacking Gender Inequality For Inclusive Development: A Case Study Of Myanmar Female Migrant Workers In Samut Sakhon Province, Thailand, Hsan Thawdar Htun Jan 2022

Unpacking Gender Inequality For Inclusive Development: A Case Study Of Myanmar Female Migrant Workers In Samut Sakhon Province, Thailand, Hsan Thawdar Htun

Chulalongkorn University Theses and Dissertations (Chula ETD)

The study aims to address the issue of gender inequality in Thailand's seafood industry, with a specific focus on Myanmar female migrant workers in Mahachai (Samut Sakhon province). Although women migrant workers play a significant role in Thailand's economy, they have been facing various challenges in low-wage industries. Gender inequality remains a prominent concern in these low-skilled labor-intensive workplaces like seafood industry. While there have been studies on migration that include both men and women or focus solely on women, gender has not received sufficient emphasis in understanding the experiences of female migrant workers, particularly in the seafood industry. This …

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Migrant Trainees And Social Inclusion : A Study Of Construction And Electronics Company In Japan, Kazuhiro Watanabe Jan 2022

Migrant Trainees And Social Inclusion : A Study Of Construction And Electronics Company In Japan, Kazuhiro Watanabe

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research analyzed the Technical Intern Training Program (TITP) by using the concept of social inclusion and discussed the factors that inhibit the social inclusion of trainees. Not much previous research on has been done on this because trainees are allowed to stay in Japan temporarily and they must go back to their home countries after the training is over. However, trainees contribute economic growth in Japan and play an important role for solving issues of the labor force. Realizing social inclusion of trainees is thus a significant issue for Japan. Factors that inhibit the social inclusion of trainees includes …

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A Study On Government Lottery Buying Behavior : The Cases Of Thai Consumers In Bangkok And Korean Consumers In Seoul Using Online Questionnaire, Korakoj Tongboriboon Jan 2022

A Study On Government Lottery Buying Behavior : The Cases Of Thai Consumers In Bangkok And Korean Consumers In Seoul Using Online Questionnaire, Korakoj Tongboriboon

Chulalongkorn University Theses and Dissertations (Chula ETD)

The research investigates the important factors influencing the government’s lottery buying behavior. The objectives of this research are to study the behavior of the lottery consumers between Thai and Korean consumers. The number of participants of Thai and Korean consumers should be separated. Among the total of 864 consumers, 445 consumers are Thai and the other 419 are Korean. This research employs a quantitative research design, and the data is collected by a questionnaire as a research tool. The data is statistically analyzed by percentage, means, standard deviation, Chi-square and Logistic Regression.The results show that the differences between Thai and …

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The Influence Of K-Pop Thai Fan Loyalty On The Image Of Korean Male Idol: A Case Study Of Lim Youngmin, Nattanon Wongsantimeth Jan 2022

The Influence Of K-Pop Thai Fan Loyalty On The Image Of Korean Male Idol: A Case Study Of Lim Youngmin, Nattanon Wongsantimeth

Chulalongkorn University Theses and Dissertations (Chula ETD)

K-pop boyband artist AB6IX from South Korea, Lim Youngmin, has won the hearts of Thai fans that have developed into loyalness to him. However, Lim Youngmin has faced situations that affected the artist's idol image, and this resulted in the inability of performing as an artist in the meantime, from an incident in 2020, after being arrested for DUI - driving under the influence of alcohol. He had his driving license revoked in the same year which might force him to decide to enlist himself in the military, which is a requirement for all male citizens of South Korea without …

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Hallyu’S Media Hybridization: A Case Study Of A Korean Series Remake For Thai Audiences, Nutchapon Nimitphuwanai Jan 2022

Hallyu’S Media Hybridization: A Case Study Of A Korean Series Remake For Thai Audiences, Nutchapon Nimitphuwanai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Korean culture has currently spread to many countries and benefited both the economy and society, but it also has the potential to integrate with those cultures. Hallyu is centered to the export of cultural products in order to further the spread of its culture throughout the world. Thailand is one of the countries that has been influenced by Hallyu, and the impact on Thai television has not exemplified cultural imperialism but hybridization. Hallyu, on the other hand, is not a single direction, but a composite of mixed and local reconstructions. Korean media imports are also incorporated into the local. Certain …

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Political Astronomy: South Korea Space Development Under The International Political Dimension, Nutnarin Ueasukpakdee Jan 2022

Political Astronomy: South Korea Space Development Under The International Political Dimension, Nutnarin Ueasukpakdee

Chulalongkorn University Theses and Dissertations (Chula ETD)

Human Knows about space technology development since 1950s era during that time U.S. and Soviet Union were main actors in “Space race” war. Space technology development of U.S. and Soviet Union in proxy war era were emphasized to develop for competition of political ideology and power of military. At the present time the purpose of space technology development different from the past, many countries that try to develop space technology for economic benefit, technology benefit, communication benefit or hidden connotation others. South Korea was the one that have potential and interesting to develop space technology because of the conflict with …

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Juxtaposition Images Of Two Koreas Portrayed In Crash Landing On You And Its Effect On Thai Audiences' Perspective, Phonpraphai Chanthanee Jan 2022

Juxtaposition Images Of Two Koreas Portrayed In Crash Landing On You And Its Effect On Thai Audiences' Perspective, Phonpraphai Chanthanee

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study examines the historical and political contexts of the two Koreas in terms of different ideologies that affect various elements of society by exploring insights into the backgrounds of South Korea and North Korea from a literature review. To analyze the disparities between the two nations, the research focuses on the scripts, visuals, and hidden agendas depicted in the renowned Korean series Crash Landing on You, along with investigating the production process and relevant interviews. In addition to exploring the narration, the study also surveyed the impact of the drama on the international perspective of the two Koreas through …

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Connected Size Ramsey Numbers Of Matching And Some Graphs, Jirawat Mungtumklang Jan 2022

Connected Size Ramsey Numbers Of Matching And Some Graphs, Jirawat Mungtumklang

Chulalongkorn University Theses and Dissertations (Chula ETD)

No abstract provided.

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Simulation And Prototyping Of A Knee Assistive Device For Improved Gait Function, Khemwutta Pornpipatsakul Jan 2022

Simulation And Prototyping Of A Knee Assistive Device For Improved Gait Function, Khemwutta Pornpipatsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to develop a knee-assistive device while walking. The research was separated into two sections: the gait support simulation in MATLAB and the prototype of the device. Data on body part positions and ground reaction force were collected from three adult Thai participants walking at a speed of 1.5 m/s to calculate knee moment. The simulation section provides support moments during walking using machine learning and artificial stiffness control strategy (MLASCS), composed of the kNN model and the instantaneous artificial stiffness per body mass (IASPB) equations. The MLASCS was used to determine the proper amount of support moment …

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Effects Of Chitosan Oligosaccharide And Probiotics On Chronic Kidney Disease Rats, Weerapat Anegkamol Jan 2022

Effects Of Chitosan Oligosaccharide And Probiotics On Chronic Kidney Disease Rats, Weerapat Anegkamol

Chulalongkorn University Theses and Dissertations (Chula ETD)

Chronic kidney disease (CKD) patients suffer from the accumulation of toxic substances in their blood due to the loss of kidney function, which results in hyperphosphatemia. This condition contributes to hyperparathyroidism, leading to the development of chronic kidney disease-related mineral bone disorder (CKD-MBD). Additionally, CKD patients experience changes in their gut microbiota, disrupting epithelial tight junctions and allowing excessive absorption of dietary phosphate. In this study, we aimed to investigate the effects of various oligosaccharides and probiotics on the gut microbiota, intestinal barrier, hyperphosphatemia, and hyperparathyroidism in CKD rats. We isolated Lactobacillus and Bifidobacterium strains from healthy participants and tested …

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Macrophage Depletion Enhances Gut Dysbiosis And Severity In Sepsis Mouse Model, Pratsanee Hiengrach Jan 2022

Macrophage Depletion Enhances Gut Dysbiosis And Severity In Sepsis Mouse Model, Pratsanee Hiengrach

Chulalongkorn University Theses and Dissertations (Chula ETD)

Macrophage is vital players in the responsiveness of the innate immune system against injury or infection. Although macrophage depletion is well-known for some emerging therapies, such as osteoporosis, osteopenia, and decreasing tumor-associated macrophages in melanoma, dysfunction of macrophages leads to an inability of an appropriate immune response and implicated in various disease processes, especially intestinal macrophages that play a key role in the gut immune system and the regulation of gastrointestinal physiology. To obtain an understanding of the role of sepsis-associated macrophages, clodronate was used for the dysfunction of mouse macrophages with and without cecal ligation and puncture (CLP) sepsis. …

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