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Articles 180451 - 180480 of 1519605
Full-Text Articles in Entire DC Network
Development Of Myelin In Wolfram Syndrome, Olga Reine Neyman
Development Of Myelin In Wolfram Syndrome, Olga Reine Neyman
Arts & Sciences Graduate Student Theses and Dissertations
Wolfram syndrome is a rare, autosomal recessive disease traditionally characterized by juvenile onset insulin dependent diabetes, optic atrophy, deafness, and neurodegeneration often beginning in childhood and adolescence. The disease is caused by mutations in WFS1, which encodes for the protein wolframin and is associated with endoplasmic (ER) stress-mediated apoptosis. ER stress-related dysfunction may inhibit production of myelin during neurodevelopment in Wolfram syndrome, as active and developing oligodendrocytes are more vulnerable to ER stress than mature ones. It is known that white matter tracts are compromised in the disease, but many questions related to the vulnerability of myelin and its impact …
Mapping Brain Development And Decoding Brain Activity With Diffuse Optical Tomography, Kalyan Tripathy
Mapping Brain Development And Decoding Brain Activity With Diffuse Optical Tomography, Kalyan Tripathy
Arts & Sciences Graduate Student Theses and Dissertations
Functional neuroimaging has been used to map brain function as well as decode information from brain activity. However, applications like studying early brain development or enabling augmentative communication in patients with severe motor disabilities have been constrained by extant imaging modalities, which can be challenging to use in young children and entail major tradeoffs between logistics and image quality. Diffuse optical tomography (DOT) is an emerging method combining logistical advantages of optical imaging with enhanced image quality. Here, we developed one of the world’s largest DOT systems for high-performance optical brain imaging in children. From visual cortex activity in adults, …
Leveraging Protein Dynamics To Drug Filovirus Protein-Nucleic Acid Interactions Using Simulations And Experiments, Matthew Alberto Cruz
Leveraging Protein Dynamics To Drug Filovirus Protein-Nucleic Acid Interactions Using Simulations And Experiments, Matthew Alberto Cruz
Arts & Sciences Graduate Student Theses and Dissertations
Drug discovery targeting protein nucleic acid (PNI) and protein-protein interactions (PPI) remains a difficult task. How to identify druggable conformations and discover compounds binding to these conformations is an unsolved problem. Here, I describe how we apply computational and experimental approaches to probe the conformational landscape of a key immune antagonist protein from the Zaire ebolavirus. Viral Protein 35 (VP35) binds to the viral pathogen associated molecular pattern, double stranded RNA (dsRNA), and blocks activation of the interferon (IFN) response. Long time scale molecular dynamics simulations reveal that VP35 adopts an alternative conformation which opens a pocket absent in experimental …
Understanding Thermotolerance In Photosynthetic Cells: From Green Algae To Land Plants, Erin Marie Mattoon
Understanding Thermotolerance In Photosynthetic Cells: From Green Algae To Land Plants, Erin Marie Mattoon
Arts & Sciences Graduate Student Theses and Dissertations
Global temperatures are increasing, causing damage to crop plants, algae, and reducing food and biofuel production. To meet increasing demand for food and energy, we must engineer thermotolerant crops and algae that will thrive in the increasingly warm environment. However, there are many things we do not understand about how photosynthetic cells cope with high temperatures. Primarily, we do not fully understand which genes are required for thermotolerance and how different intensities and durations of high temperature periods may change this list. In this thesis, I employed high-throughput, quantitative, and genomic approaches including transcriptomics, proteomics, and genome-wide pooled mutant screens …
Spike-Timing-Dependent Plasticity Alters Sensory Network Connectivity, Adalee Lube
Spike-Timing-Dependent Plasticity Alters Sensory Network Connectivity, Adalee Lube
Arts & Sciences Graduate Student Theses and Dissertations
A fundamental question in neuroscience is: how does a sensory system optimize detection of behaviorally relevant stimuli, when those stimuli and the sensory environment are constantly changing? Spike-timing-dependent plasticity (STDP), in which synapse strength changes based on the relative timing of pre- and post-synaptic spiking, has been implicated in changes in neuronal connectivity thought to underlie learning and memory. Synaptic strength changes caused by STDP have been shown in optic tectum, visual cortex, hippocampus, and other brain regions in vitro across many organisms like fish, frogs, and mice. Although it is possible that STDP mechanisms underlie changes in sensory neuron …
The Effect Of Oxytocin Receptor Genetic Variants On Oxytocin Response, Manasi Malik
The Effect Of Oxytocin Receptor Genetic Variants On Oxytocin Response, Manasi Malik
Arts & Sciences Graduate Student Theses and Dissertations
Oxytocin is a nonapeptide hormone that modulates social behavior, mediates the lactation reflex, and induces and strengthens uterine contractions. Each year, oxytocin is administered to about half of laboring patients for induction and augmentation, and to almost all patients for prevention of post-partum hemorrhage – a total of four million patients per year in the United States alone. However, response to oxytocin varies widely between individuals, and complications including uterine hyperstimulation, uterine atony, required Cesarean section, and postpartum hemorrhage can arise from either excessive or inadequate oxytocin response. To avoid these adverse events, it is critically important to identify individuals …
Zebrafish Swim Capacity, Gait, And Posture During Innate Spinal Cord Repair, Nicholas Oliver Jensen
Zebrafish Swim Capacity, Gait, And Posture During Innate Spinal Cord Repair, Nicholas Oliver Jensen
Arts & Sciences Graduate Student Theses and Dissertations
Adult zebrafish are capable of anatomical and functional recovery following severe spinal cord injury. Significant advances for understanding the cellular and molecular mechanisms of innate spinal cord repair are best supported by accurate assessment of swim function. This study introduces neuromuscular-associated measurements derived from gait and posture, compares new and classical functional measurements longitudinally, and provides a comprehensive correlative analysis of various functional and cellular regeneration outputs. It also explores trajectories of functional regeneration through tensor decomposition and demonstrates that swim function at 2 weeks post-injury can be used to predict 8-week regeneration outcomes. By establishing swim quality metrics which …
Solo Dance In Greek And Roman Comedy, Marleigh Anderson
Solo Dance In Greek And Roman Comedy, Marleigh Anderson
Arts & Sciences Graduate Student Theses and Dissertations
In the first full-length study focusing exclusively on comic solo dance, I argue for the presence and significance of solo dance in both Greek and Roman comedy. My dissertation aims to answer two driving questions: where does solo dance (broadly defined as dance by actors) occur in extant Greek and Roman comedy, and how does such dancing contribute to the plays? The introduction lays out my methodology for approaching these questions. My study then moves from what can be known with certainty (definite solo dance scenes and references to dance) to what requires more speculation (likely dance scenes). Chapter one, …
Ragd Auto-Activating Mutations Impair Mit/Tfe Activity In Kidney Tubulopathy And Cardiomyopathy Syndrome, Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E G De Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Ballabio
Ragd Auto-Activating Mutations Impair Mit/Tfe Activity In Kidney Tubulopathy And Cardiomyopathy Syndrome, Irene Sambri, Marco Ferniani, Giulia Campostrini, Marialuisa Testa, Viviana Meraviglia, Mariana E G De Araujo, Ladislav Dokládal, Claudia Vilardo, Jlenia Monfregola, Nicolina Zampelli, Francesca Del Vecchio Blanco, Annalaura Torella, Carolina Ruosi, Simona Fecarotta, Giancarlo Parenti, Leopoldo Staiano, Milena Bellin, Lukas A Huber, Claudio De Virgilio, Francesco Trepiccione, Vincenzo Nigro, Andrea Ballabio
Duncan NRI Faculty and Staff Publications
Heterozygous mutations in the gene encoding RagD GTPase were shown to cause a novel autosomal dominant condition characterized by kidney tubulopathy and cardiomyopathy. We previously demonstrated that RagD, and its paralogue RagC, mediate a non-canonical mTORC1 signaling pathway that inhibits the activity of TFEB and TFE3, transcription factors of the MiT/TFE family and master regulators of lysosomal biogenesis and autophagy. Here we show that RagD mutations causing kidney tubulopathy and cardiomyopathy are "auto- activating", even in the absence of Folliculin, the GAP responsible for RagC/D activation, and cause constitutive phosphorylation of TFEB and TFE3 by mTORC1, without affecting the phosphorylation …
Glutamatergic Cerebellar Neurons Differentially Contribute To The Acquisition Of Motor And Social Behaviors, Meike E Van Der Heijden, Alejandro G Rey Hipolito, Linda H Kim, Dominic J Kizek, Ross M Perez, Tao Lin, Roy V Sillitoe
Glutamatergic Cerebellar Neurons Differentially Contribute To The Acquisition Of Motor And Social Behaviors, Meike E Van Der Heijden, Alejandro G Rey Hipolito, Linda H Kim, Dominic J Kizek, Ross M Perez, Tao Lin, Roy V Sillitoe
Duncan NRI Faculty and Staff Publications
Insults to the developing cerebellum can cause motor, language, and social deficits. Here, we investigate whether developmental insults to different cerebellar neurons constrain the ability to acquire cerebellar-dependent behaviors. We perturb cerebellar cortical or nuclei neuron function by eliminating glutamatergic neurotransmission during development, and then we measure motor and social behaviors in early postnatal and adult mice. Altering cortical and nuclei neurons impacts postnatal motor control and social vocalizations. Normalizing neurotransmission in cortical neurons but not nuclei neurons restores social behaviors while the motor deficits remain impaired in adults. In contrast, manipulating only a subset of nuclei neurons leaves social …
Cardiac Pericytes Mediate The Remodeling Response To Myocardial Infarction, Pearl Quijada, Shuin Park, Peng Zhao, Kamal Ss Kolluri, David Wong, Kevin D Shih, Kai Fang, Arash Pezhouman, Lingjun Wang, Ali Daraei, Matthew D Tran, Elle M Rathbun, Kimberly N Burgos Villar, Maria L Garcia-Hernandez, Thanh Td Pham, Charles J Lowenstein, M Luisa Iruela-Arispe, S Thomas Carmichael, Eric M Small, Reza Ardehali
Cardiac Pericytes Mediate The Remodeling Response To Myocardial Infarction, Pearl Quijada, Shuin Park, Peng Zhao, Kamal Ss Kolluri, David Wong, Kevin D Shih, Kai Fang, Arash Pezhouman, Lingjun Wang, Ali Daraei, Matthew D Tran, Elle M Rathbun, Kimberly N Burgos Villar, Maria L Garcia-Hernandez, Thanh Td Pham, Charles J Lowenstein, M Luisa Iruela-Arispe, S Thomas Carmichael, Eric M Small, Reza Ardehali
Faculty, Staff and Students Publications
Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to the injury site and expressed profibrotic genes, coinciding with increased vessel leakage after myocardial infarction (MI). Single-cell RNA-Seq of cardiac pericytes at various time points after MI revealed the temporally regulated induction of genes related to vascular permeability, extracellular matrix production, basement membrane degradation, and TGF-β signaling. Deleting TGF-β receptor 1 in chondroitin sulfate proteoglycan 4-expressing (Cspg4-expressing) cells reduced fibrosis following MI, leading to a transient improvement in the cardiac …
Loneliness And Social Networks Of Older Adults In Rural Communities: A Narrative Synthesis Systematic Review, Basharat Hussain, Mahrukh Mirza, Rebecca Baines, Lorna Burns, Sebastian Stevens, Sheena Asthana, Arunangsu Chatterjee
Loneliness And Social Networks Of Older Adults In Rural Communities: A Narrative Synthesis Systematic Review, Basharat Hussain, Mahrukh Mirza, Rebecca Baines, Lorna Burns, Sebastian Stevens, Sheena Asthana, Arunangsu Chatterjee
Peninsula Medical School
Introduction: Loneliness has significant impacts on the health of older adults. Social networks help to improve psychosocial and quality of life outcomes among older adults. A fifth of older adults live in rural communities, where geographic isolation poses challenges to health. The dynamics of social networks of older adults in rural communities has not been explored. Objective: To synthesize the literature related to loneliness and social networks of older adults in rural settings. Methods: A mixed-methods systematic review was conducted through searching six bibliographic databases to retrieve peer-reviewed literature with no time limits. We performed a methodological assessment of each …
Institutional Repositories For Higher Educational Institutions: A New Opportunity For Academic Libraries, Taher Hussain Khan Mr.
Institutional Repositories For Higher Educational Institutions: A New Opportunity For Academic Libraries, Taher Hussain Khan Mr.
Library Philosophy and Practice (e-journal)
Digital information created for pedagogical and research purposes is gaining traction, and there is a growing interest within academic institutions to gather, archive, and provide value-added services based on this content. The term "institutional repository" refers to a novel system for storing and sharing digital academic works produced by students and teachers at different educational institutions. It was conceived as a solution to the issues plaguing the present model of scholarly communication, which is dominated by for-profit journal publishers and suppliers. Libraries will need to hire librarians with knowledge of digital collection management and the Open Archive Information System (OAIS) …
The Impact Of Continuing Professional Development Programs On Service Delivery At Uganda Christian University Library., Kizito Mayira
The Impact Of Continuing Professional Development Programs On Service Delivery At Uganda Christian University Library., Kizito Mayira
Library Philosophy and Practice (e-journal)
The study was about the Impact of Continuing Professional Development programs on service delivery at Uganda Christian University Library. The main objective of the study was to assess how CPD programs have affected librarians’ service delivery at Uganda Christian University Library. The study employed a descriptive survey design. Data was collected through 28 questionnaires distributed physically to library staff. The findings of the study indicated that UCU library staff have attended CPD programs in form of Workshops, internal and external training programs, workshops, conferences, job shadowing, mentoring and focus groups. These have helped them acquire skills in customer care, presentation, …
Conference Program, Yue Kuo
Conference Program, Yue Kuo
Semiconductor Technology for Ultra Large Scale Integrated Circuits and Thin Film Transistors (ULSIC VS TFT 8)
No abstract provided.
Our Magnitude And Bond: An Ethics Of Care For Art Museum Education, Dana Carlisle Kletchka
Our Magnitude And Bond: An Ethics Of Care For Art Museum Education, Dana Carlisle Kletchka
Journal of Social Theory in Art Education
This work responds to contemporary concerns about the future of art museum education and public practice and art museums more broadly in the wake of a global pandemic that has, at present, killed more than a million people in the United States and sickened millions more. I respond to questions posed by the board of the Journal of Social Theory in Art Education in relation to the theme of Inclusion Invasion, expand upon the relations between art museums and communities posited by a post-critical, socially responsive museological framework, and explore the potential for a feminist philosophical Ethics of Care …
The Body Knows: Embodiment And Whiteness A Rhetorical Analysis Of White Bodies Engaged In Antiracism Work, Otsego County, New York, Kerry Lynn Mess
The Body Knows: Embodiment And Whiteness A Rhetorical Analysis Of White Bodies Engaged In Antiracism Work, Otsego County, New York, Kerry Lynn Mess
Theses - ALL
Multiculturalism, diversity, inclusion, equity, antiracism, belonging… The humanities, social sciences, and rhetorical scholarship have all slowly given attention to questions of race and racism. Situated at the intersection of somatic psychology and rhetorical studies, this thesis uses a somatic theory lens to explore how symbolic systems, specifically language and bodies, are intertwined to understand the embodied or material effects of racism we have not yet accounted for. I borrow Karma Chávez’s language of “abstract” and “actual” (2018) to observe the rhetorical dynamics, patterns and strategies, of white bodies accounting for themselves and apply Resmaa Menakem and Douglas Robinson’s somatic theories …
The Creative Link: Creativity, Resilience, Connection And Story, Elisha Stasko
The Creative Link: Creativity, Resilience, Connection And Story, Elisha Stasko
Theses - ALL
This study examines the intersection between the theories of Campbell's 'The Hero'sJourney,' Brown's 'Rising Strong,' and Catmull's 'Creativity, Inc..' and the experiences of various photographers who have undertaken projects on motherhood. Using a mixed-methods approach, the study analyzes books, interviews, blog entries, documentaries, articles and artist statements to identify patterns and themes. The study finds a consistent pattern of challenge, risk, vulnerability, and struggle, resulting in growth and connection. It concludes the creative process has parallels to patterns of resilience and the narrative arc and can facilitate connection with self and others. By recognizing this pattern in a variety of …
Theaters Of The Intimate: The Feminine Culture Of Self-Care On Tiktok, Rayana Weller
Theaters Of The Intimate: The Feminine Culture Of Self-Care On Tiktok, Rayana Weller
Theses - ALL
In this thesis, I study the feminine culture of self-care on TikTok as it exists in prominent digital genres: skincare and soft living. These two genres represent the aspiration toward a soft perfection of both the physical self and the space around it. Situated within the theories of the female complaint (Berlant, 2008) and the paradigm of perfection (McRobbie, 2015), I argue that feminine culture on TikTok reframes the demanding and unending labor required to approximate standards of feminine perfection as a pleasing and satisfying experience of self-care. Self-care rhetoric on TikTok disguises the discipline required to pursue cultural definitions …
“They Need To Hear Our Voices:” Youth Dialogue, Participatory Research, And Educational Inequity In Central New York, Lauren Eleanor Ashby
“They Need To Hear Our Voices:” Youth Dialogue, Participatory Research, And Educational Inequity In Central New York, Lauren Eleanor Ashby
Theses - ALL
While youth are active participants in urban and educational spaces, young people’s lived experiences are understudied in geography. In this study, I investigate the ways that youth in Central New York understand, communicate, and navigate their schools and neighborhoods through ethnography and participatory research. Situating the city of Syracuse contextually, this study uncovers the way that youth know and enact the spaces of their daily lives, and the impacts of external reputations and relational systems on how these spaces are navigated. I investigate these themes through two case studies. The first is the Common Ground Dialogue program, a school-based intergroup …
Soft Thorns: Uncovering Vulnerability, Qianjin Men
Soft Thorns: Uncovering Vulnerability, Qianjin Men
Theses - ALL
The paper titled “Soft Thorns: Uncovering Vulnerability” summarizes my creative journey and evolution in the art field, as well as how I used various art forms to heal myself during my three-year graduate study. It supplies a detailed account of my artworks created during my time at Syracuse University, including my final work, Soft Thorns. Despite undergoing significant changes in my art style and work due to the passage of time and external influences, the fundamental essence of my artwork has remained centered around exploring my inner emotions and battling mental conflicts. Through experimenting with various artistic mediums such as …
Towards Decolonization: Migrated Kenyan Archives And The Politics Of Knowledge Production, Joy Nyokabi Karinge
Towards Decolonization: Migrated Kenyan Archives And The Politics Of Knowledge Production, Joy Nyokabi Karinge
Theses - ALL
“Towards Decolonization: Migrated Kenyan Archives and the Politics of Knowledge Production” examines ethical questions of archival removal in relation to access to knowledge and the politicization of access. Utilizing a theoretical framework of postcolonial theory, decolonial theory, and epistemic decolonization, this study investigates Kenyan archival holdings within the Foreign and Commonwealth Office files at The National Archives in London and the East African Archives at Syracuse University. Analysis of these archives is conducted using qualitative methods of archival research and interviews. This research reveals British colonial efforts to protect its reputation by migrating, concealing, and destroying archives and to preserve …
Contingencies In Classrooms: A Systematic Review Of Contingent Reinforcement For Academic Performance, Taylor Jean Hitchings
Contingencies In Classrooms: A Systematic Review Of Contingent Reinforcement For Academic Performance, Taylor Jean Hitchings
Theses - ALL
Contingency-based reinforcement interventions, in which students receive a reward for engaging in desired behaviors, have been used to target various behaviors at school. Previous research studies’ findings suggest that contingency-based reinforcement interventions can be used to target a variety of behaviors, including task engagement, appropriate classroom etiquette, and academic performance across a variety of subjects. The purpose of this systematic review was to synthesize the assessment and intervention practices of 98 studies (from 1969 to 2021) that examined the effects of contingency-based reinforcement interventions when academic performance was directly targeted in the areas of math, reading, writing, spelling, and English …
The Passing Intensities Of A Neighborhood. Sensing Atmospheres In La Boca, Gabriel Tomas O'Rourke
The Passing Intensities Of A Neighborhood. Sensing Atmospheres In La Boca, Gabriel Tomas O'Rourke
Theses - ALL
The neighborhood of La Boca, located in the city of Buenos Aires, is an urban space burdened with a story and a unique aesthetic that differentiates it from other barrios in the city. In 2022, I visited this area to walk its streets, with the goal of understanding what elements marked this urban area as a distinctive place in the city. Situated within the rhetoric of space and place, this study relies on the concept of atmospheres developed by Gernot Böhme to account for the way the experience of place is constituted by an interplay between bodies, materiality and spaces. …
With-In-Through, Rumpelstiltskin Anne Morgan
With-In-Through, Rumpelstiltskin Anne Morgan
Theses - ALL
I invite you to join me on a wandering into/besides/returning with ecological-attunement through gatherings, exercises, reflections, and poetry; conversing with the prior as they are as present as the current. Everything has a way of oozing together, losing perceived independence and joining in inter-dependent choreographies.
The Politics Of Care: An Analysis Of The Lives And Stories Of Black Birth Workers In New York City, Mayannah Beauvoir
The Politics Of Care: An Analysis Of The Lives And Stories Of Black Birth Workers In New York City, Mayannah Beauvoir
Theses - ALL
“The Politics of Care: An Analysis of the Lives and Stories of Black Birth Workers in New York City'' examines the complex relationship between Black birth workers and the state. Black birth work, traditionally, has existed as resistance to state policies and actors that limited Black women’s reproductive freedom. In New York City, where Black maternal mortality and morbidity outcomes are comparable to the national average, the state has mobilized to produce the Citywide Doula Initiative, a program designed to provide free birth worker support to families in financial need. Considering the violent relationship between birth workers and the state, …
The Utopian Quest: A Visual And Cultural Exploration Of Ideal Lands, Lingyin Luo
The Utopian Quest: A Visual And Cultural Exploration Of Ideal Lands, Lingyin Luo
Theses - ALL
This thesis explores the concept of utopia across different cultures, analyzing the ideal lands in Eastern and Western societies. The author categorizes utopian ideals into two types: Thomas More-style utopias, which aim for social and political perfection, and Arcadian ideals, which prioritize individual inner peace and escape from society. The author compares the ways of entering, the environments, the lifestyles, and the consequences of leaving mentioned in these stories to identify the visual language involved. These visual elements of ideal lands provide a solid foundation for the author's visual thesis, a video game that allows players to build their own …
Associations Between Parental Separation In Adolescence And Romantic Relationship Quality In Emerging Adulthood, Chloe Ludden
Associations Between Parental Separation In Adolescence And Romantic Relationship Quality In Emerging Adulthood, Chloe Ludden
Theses - ALL
Abstract Parental separation can impact multiple aspects of an individual’s life, including romantic relationship satisfaction (Amato, 2010). Albert Bandura’s social learning theory suggests that children model their behavior based on their parents’ example, which means those whose parents separate may adopt similar relationship practices that lead to their eventual separation with their romantic partner– this could contribute to the pattern of divorce being more common in those whose parents’ divorced (Amato & Deboer, 2001; Bandura, 1977; Ross & Mirowsky, 1999). It is important to interrupt this pattern to prevent the cycle of negative impacts of parental divorce on children being …
Macroproblems Require Microsolutions: The Case For Microgrids In The U.S. Energy Infrastructure, David Howie
Macroproblems Require Microsolutions: The Case For Microgrids In The U.S. Energy Infrastructure, David Howie
Student Theses 2015-Present
This paper explores the shortcomings of the modern United States Power Grid in the face of climate change and worsening climate conditions, and seeks to explore how alternative styles of power grids could be viable replacements for current designs. The power grid is one of the most fundamental aspects of modern life, without it there would be no reliable energy supply to power devices and machinery. Oftentimes when energy generation is discussed in the United States, it only focuses on the source of generation for the energy, not the transmission of the energy. The lack of complete discussion around this …
Implementation Of A Biometric Screening Program And Wellness Coaching Program In A Hospital Employee Wellness Center, Carl Gastanes
Implementation Of A Biometric Screening Program And Wellness Coaching Program In A Hospital Employee Wellness Center, Carl Gastanes
Doctor of Nursing Practice Scholarly Projects
Background: Wellness programs are an emerging priority among organizations concerned about employee wellness and productivity. Data from Long Island Jewish Medical Center (LIJMC) revealed that in 2019 there were 1,690 employee visits to the ER due to chronic diseases; 30% were classified as ER sick visit and 40% of employees who visited the ER had no primary care provider. Many companies use biometric screening and health risk assessment to measure the health of their employees. The purpose of this improvement project was to implement a biometric screening program (BSP) that included wellness coaching to improve the health outcomes of LIJMC …