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Articles 16291 - 16320 of 1517246
Full-Text Articles in Entire DC Network
Tiny Tusks Internship: Factors That Affect Breastfeeding In Public, Caroline E. Bene
Tiny Tusks Internship: Factors That Affect Breastfeeding In Public, Caroline E. Bene
The Eleanor Mann School of Nursing Undergraduate Honors Theses
The purpose of this review was to explore factors that impact women’s decision to breastfeed in public or not. The PICOT question used was: ‘What Factors Affect Women’s Decision to Breastfeed in Public or Not?’ Two platforms, EBSCOhost and The National Library of Medicine, were used to identify 15 peer-reviewed journal articles on factors affecting women’s decision to breastfeed in public or not. The factors that impact a women’s decision on whether it is acceptable to breastfeed in public stems from the media stigmatizing that breastfeeding should be a private action. Research done yielded results of both positive and negative …
Industrial Organization Of The U.S. Short-Term Rental Industry A Layered Structure–Conduct–Performance Analysis, Carlos Rodriguez
Industrial Organization Of The U.S. Short-Term Rental Industry A Layered Structure–Conduct–Performance Analysis, Carlos Rodriguez
Theses & ETDs
This thesis analyzes the U.S. short-term rental industry using a Structure–Conduct–Performance framework to explain how control over demand access is centralized at the platform level, while pricing, revenue generation, and competition play out across distinct local markets at the operator level. The industry does not operate as a simple platform-versus-host model. It runs in layers that are connected through supply. At the top, platforms control demand access through search rankings, platform rules, and distribution, which allows them to influence visibility and booking flow across the entire system. In the middle sits the supply layer. Homeowners and investors decide whether to …
Ai And The Ethos Of Education: Reflections On Human Learning Past And Present, Melanie Trotochaud
Ai And The Ethos Of Education: Reflections On Human Learning Past And Present, Melanie Trotochaud
Yale Divinity School Theses
This thesis reflects on contemporary issues of “Artificial Intelligence” (AI), while also bringing into conversation 12th century Christian mystic and polymath Hildegard Von Bingen and 18th century Humanist philosopher Giambattista Vico. Hildegard’s and Vico’s contexts philosophically and historically share similarities to our present moment: reassessing our humanity and learning in times of technological, economic, and social shifts. Holding up their writing to various conversations about our contemporary world helps illuminate the present. Key aspects of the discussion include what constitutes tools or technologies, the agency we have in choosing to use or not to use them, and how we make …
The Role Of Executive Functions In Creativity, Gavin R. Kyer
The Role Of Executive Functions In Creativity, Gavin R. Kyer
Biological Sciences Undergraduate Honors Theses
The present study investigates the relationship between executive functions and creativity, measured through divergent thinking. Literature review determines that there should be a positive correlation between executive functioning and creative idea generation, however, findings are mixed. This study tested the level of correlation/predictability between executive functions, specifically, updating, shifting, and inhibition, and creativity. Participants (N=112) completed tasks assessing updating (letter memory), shifting (number letter) and inhibition (Stroop). They also completed the Alternative Uses Task (AUT) that measures divergent thinking. Pearson’s correlations and multiple regression analyses were conducted to examine any individual or combined relationship between executive functions and creativity. Results …
State Of Discovery, 2026, Division Of Research And Economic Development
State Of Discovery, 2026, Division Of Research And Economic Development
State of Discovery South Dakota State University's Research Magazine
[Page] 2 R1 Our Way Update
[Page] 2 SDSU Research Spinoff Companies
[Page] 3 The future of agriculture
[Page] 8 Addressing the rural nursing crisis
[Page] 9 Repurposing drugs to create cancers and other diseases
[Page] 10 South Dakota's rural firefighters
[Page] 11 Natural food coloring
[Page] 12 Raising the ROI of Research
[Page] 13 Can ancient bacteria help solve one of agriculture's biggest challenges?
From Admission To Achievement: Evaluating The Predictive Validity Of Entrance Exams And Grade Point Average In Nursing Education, Kristen Fenlason
From Admission To Achievement: Evaluating The Predictive Validity Of Entrance Exams And Grade Point Average In Nursing Education, Kristen Fenlason
Education Doctorate Dissertations
At a critical time of nursing shortages, nursing programs must examine admission gatekeeping practices. The two common admission metrics, grade point average (GPA) and entrance exam scores, are inconsistently supported in the literature, particularly within the understudied population of practical nursing students. This quantitative, retrospective, correlational study examined the relationship between admission criteria and three measures of practical nursing student success: on-time first-semester completion, on-time program completion, and first-time NCLEX-PN pass rate. Data were collected from historical records of five cohorts of practical nursing students (n = 94) at a medium-sized community college from Fall 2020 to Fall 2024. …
Integrated Management Of Procambarus Clarkii Through Habitat Manipulation And Chemosensory Predator Avoidance, Allarae J. Prigan
Integrated Management Of Procambarus Clarkii Through Habitat Manipulation And Chemosensory Predator Avoidance, Allarae J. Prigan
Biology Theses
Aquatic invasive species pose a significant threat to native biodiversity, water quality, and local economies. The Laurentian Great Lakes are especially at risk with over 180 established non-native species. In particular, the red swamp crayfish (Procambarus clarkii) is a recent invader to the Lake Erie eastern watershed and requires sustained management to prevent its spread further into the region. This thesis explores a multi-faceted approach to managing this species via a habitat manipulation study and a laboratory behavior experiment.
I assessed the outcomes of winter stream dewatering on population catch per unit effort (CPUE), mean animal size, and …
Companion Parrot Vocal Learning And Reproduction Of Human Speech Sounds, Karla Vilches Castaño
Companion Parrot Vocal Learning And Reproduction Of Human Speech Sounds, Karla Vilches Castaño
Master's Theses
Vocal learning is rare among animals but is well developed in parrots, which can imitate novel sounds and, in captive settings, reproduce human speech. This study helps address a larger evolutionary question about vocal learning. Specifically, whether vocal learning ability is best understood as a single generalized trait or as a multi-dimensional system in which different acoustic features can be learned and reproduced with varying degrees of fidelity. This thesis quantifies how closely companion parrots match their human tutors across three acoustic dimensions (spectrographic structure, intensity contour, and pitch contour) and tests whether mimicry accuracy varies among individuals, differs between …
Technology-Supported Literacy Instruction In Elementary Classrooms (K-5): Perspectives Of Student Teachers In Western Kentucky, Ila B. Shirrell
Technology-Supported Literacy Instruction In Elementary Classrooms (K-5): Perspectives Of Student Teachers In Western Kentucky, Ila B. Shirrell
Honors College Theses
The use of technology in elementary classrooms (kindergarten–fifth grade) has increased significantly with the goal of enhancing instruction. Additionally, educational technology is being used to improve literacy skills, reading recovery, and comprehension. This study examined how technology supports literacy development and instruction in elementary classrooms by drawing upon the perspectives of current student teachers. Student teachers from Murray State University, placed in third through fifth grade classrooms in Western Kentucky, were interviewed. The interviews assessed how technology was used for literacy instruction, including the extent of its effectiveness and potential challenges. Responses were transcribed and analyzed. The themes of evidence-based …
Evaluating The Rural/Urban Divide In Conservation: Methods Of Improvement In Conservation Programming Across Kentucky, Lauren Tackett
Evaluating The Rural/Urban Divide In Conservation: Methods Of Improvement In Conservation Programming Across Kentucky, Lauren Tackett
Honors College Theses
Kentucky’s lands and waterways have always defined the state. Our unique karst landscape, combined with the Appalachian Mountains and Ohio River, help characterize the state and its identity. However, across Kentucky conservation efforts within recent years have been under attack. Through legislation changes and policy challenges, various bills have sought to repeal Kentucky’s conservation efforts regarding water, soil, and land use. Furthermore, there has been a rise in environmental disasters within the state that cause long term issues for both rural and urban communities to contend with. The responsibility of land stewardship falls on a variety of entities but weighs …
2026 Workshop On Bridging The Gaps: Tackling Microplastics And Nanoplastics Challenges In Coastal Ecosystems, Shenghua Wu, Kaushik Venkiteshwaran, Melike Dizbay-Onat, Alexandra Stenson, Jinhui Wang, Tina Miller-Way, Ebenezer Nyadjro, Bhuvnesh Bharti, John Weinstein, Yi Bao, Shihui Shen, Valerie Longa, Shenghua Zha, John Cleary, Marty Lind
2026 Workshop On Bridging The Gaps: Tackling Microplastics And Nanoplastics Challenges In Coastal Ecosystems, Shenghua Wu, Kaushik Venkiteshwaran, Melike Dizbay-Onat, Alexandra Stenson, Jinhui Wang, Tina Miller-Way, Ebenezer Nyadjro, Bhuvnesh Bharti, John Weinstein, Yi Bao, Shihui Shen, Valerie Longa, Shenghua Zha, John Cleary, Marty Lind
Workshops
This report presents the findings from the 2026 Workshop on Tackling Microplastics and Nanoplastics (MNPs) in Coastal Ecosystems, which took place in Mobile, Alabama. More than 140 experts from universities, government, industry, and community organizations gathered to address the increasing issue of MNPs in coastal regions.
Beyond Challenging Up: How Organizational Climate Shapes Externally-Oriented Courage In The Workplace, Morgan Chandler
Beyond Challenging Up: How Organizational Climate Shapes Externally-Oriented Courage In The Workplace, Morgan Chandler
All Dissertations
Employees often face situations that confront them with the decision to do the right thing at work despite risk, which requires courage. This dissertation introduces a new form of workplace courage: challenging-around, which, in the context of the present study, involves pushing back against external stakeholders to uphold issues like ethical standards, organizational integrity, or professional judgement. Guided by Worthwhile Risk Theory, the study examined how organizational climate and moral courage influence this behavior. Results show that supportive, goal-promoting climates increase challenging-around, while moral courage independently predicts challenging-around. Additionally, the study validates a researcher-developed measure of challenging-around. Overall, findings suggest …
Central Pattern Generator Test Bench Report, Stephanie Wing-Yee Lee, Dustin Wong, Joseph Hernandez
Central Pattern Generator Test Bench Report, Stephanie Wing-Yee Lee, Dustin Wong, Joseph Hernandez
Electrical Engineering
The project presents the design, fabrication, and implementation of a PCB test bench that interfaces with a custom VLSI chip designed to emulate the neural activity of a Central Pattern Generator (CPG). The test bench provides a precise and reliable platform for supporting signal operations and validating neuromorphic functionality. The design integrates both analog and digital circuitry to provide stable biasing, signal routing, and measurement access for chip characterization. The incorporation of op-amp buffers and adjustable potentiometers enables precise voltage tuning, resulting in controlled neuron-like behavior within the custom IC. The two-layer PCB supports modular interfacing with standard laboratory instruments …
Concerned Philosophers For Peace, Vol. 34 (2026), Concerned Philosophers For Peace
Concerned Philosophers For Peace, Vol. 34 (2026), Concerned Philosophers For Peace
Concerned Philosophers for Peace
In addition to organizational information, honors, awards, and calls for papers and abstracts, this issue contains the following articles:
- “Genocide, Evil, and The Madman's Bluff: The Moral Stain of President Trump's Shameful Threat to Annihilate Iran,” by Andrew Fiala
- “Lest We Forget,” by Anna Malavisi
- “Ancient Lessons on Peace from a Roman Dissident,” by Court Lewis
Taking The Lex Mercatoria To Space, Tatiana Sainati
Taking The Lex Mercatoria To Space, Tatiana Sainati
Arbitration Law Review (2009 - Present)
No abstract provided.
Unenforceability Of Arbitration Clauses: How Recent Canadian Decisions Impact The Legitimacy Crisis In International Arbitration, Jamie Gomes
Arbitration Law Review (2009 - Present)
No abstract provided.
Functional Heterogeneity In Trophoblast Stem Cells Derived From Recurrent Pregnancy Loss Products Of Conception., Qi Fu, Keisuke Kozai, Xingrao Ke, Joe Varberg, Sheng Xia, Ashley S. Howard, Michael Lydic, Kristin Holoch, Courtney Marsh, Elin Grundberg, Kaela Varberg
Functional Heterogeneity In Trophoblast Stem Cells Derived From Recurrent Pregnancy Loss Products Of Conception., Qi Fu, Keisuke Kozai, Xingrao Ke, Joe Varberg, Sheng Xia, Ashley S. Howard, Michael Lydic, Kristin Holoch, Courtney Marsh, Elin Grundberg, Kaela Varberg
Manuscripts, Articles, Book Chapters and Other Papers
Recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages, affects 1-5% of couples attempting to conceive and most frequently occurs between 6 and 8 weeks of gestation, coinciding with critical stages of placental development. Despite this temporal association, placental contributions to RPL pathogenesis remain poorly understood. We hypothesized that trophoblast lineage development, including extravillous trophoblast (EVT) and syncytiotrophoblast (STB) differentiation, are disrupted in RPL. To test this hypothesis, we established and functionally characterized human trophoblast stem (TS) cell lines derived from products of conception (POC) obtained from consenting idiopathic RPL cases. Four TS cell lines were successfully derived …
The Use And Efficacy Of Non-Verbal Gestures In Applied Studio Voice Instruction And Vocal Coaching, Mark Eugene Lubas
The Use And Efficacy Of Non-Verbal Gestures In Applied Studio Voice Instruction And Vocal Coaching, Mark Eugene Lubas
Dissertations
Despite important innovations in the use of technology in vocal instruction, individualized, faceto- face communication remains the predominant delivery modality for applied voice lessons and vocal coaching. Applied voice instructors and vocal coaches consistently identify non-verbal, gestural communication as a significant dimension of these instructional interactions. Existing scholarship has examined the expressive use of gesture in musical performance, the role of gesture in facilitating pitch accuracy acquisition among young singers, and the neurological responses of singers to gestural input. However, systematic investigation of gesture as a pedagogical instrument from the perspective of the instructor remains underdeveloped in the literature. This …
Practices And Strategies Used In Classrooms For Children Who Are Deaf With Autism, Jennifer Anne Hills
Practices And Strategies Used In Classrooms For Children Who Are Deaf With Autism, Jennifer Anne Hills
Dissertations
Deaf education has a history spanning more than 200 years; however, there remain relatively few evidence-based practices specifically identified for use with children who are deaf or hard-of-hearing (DHH; Cawthon & Carrie, 2021). In contrast, autism as a diagnostic and educational category is a much more recent phenomenon. Just over 80 years ago, Donald Triplett, became the first person diagnosed with autism in the United States (Donovan & Zucker, 2016). The diagnosis and education of autism is a newer phenomenon with strong research underpinnings. Conversely, the field of deaf education has existed for over 200 years, yet few evidence-based practices …
The Relationship Of Analysis And Performance In Henri Tomasi’S Concerto Pour Trombone Et Orchestre, Craig Owen Hull
The Relationship Of Analysis And Performance In Henri Tomasi’S Concerto Pour Trombone Et Orchestre, Craig Owen Hull
Dissertations
Henri Tomasi’s Concerto pour Trombone et Orchestre is regarded as one of the most important pieces within the trombone solo repertoire. However, neither Tomasi nor his Concerto pour Trombone et Orchestre have received a notable amount of scholarly attention. This is likely due to Tomasi’s obscurity to a general audience and too few trombonists engaging in analytical and historical scholarly endeavors. However, the quality of the composer, his work, and the lack of scholarship surrounding it encourage such a study to exist.
The music theory discipline known as analysis and performance relies on analysis and historical context. The combination of …
Between The Lines And Behind The Lessons: An Educational Criticism Of Bridging Anti-Bias Possibilities In Colorado’S K-2 Standards And Classrooms, Grace Marguerite Breiten
Between The Lines And Behind The Lessons: An Educational Criticism Of Bridging Anti-Bias Possibilities In Colorado’S K-2 Standards And Classrooms, Grace Marguerite Breiten
Dissertations
In an era of standardized accountability in public education, anti-bias-oriented Colorado educators have sought to foster caring, courageous, and critically conscious citizens by affirming student identity, promoting diversity, demanding justice, and inspiring activism, all while adhering to mandated academic standards. The purpose of the qualitative Educational Critical and Connoisseurship study was to understand and describe how K-2 anti-bias-oriented educators teaching in public schools in Colorado interpreted and implemented Colorado’s Reading, Writing, and Communicating (RWC) and Social Studies (SS) standards using an anti-bias orientation. This study was guided by the following research questions:
Q1 In what ways are Colorado’s K–2 Reading, …
Ai-Powered Insights In Pediatric Nephrology: Current Applications And Future Opportunities., Arwa Nada, Yamen Ahmed, Jieji Hu, Darcy K. Weidemann, Gregory H. Gorman, Eva Glenn Lecea, Ibrahim A. Sandokji, Stephen Cha, Stella Shin, Salar Bani-Hani, Sai Sudha Mannemuddhu, Rebecca L. Ruebner, Aadil Kakajiwala, Rupesh Raina, Roshan George, Rim Elchaki, Michael L. Moritz, The American Society Of Pediatric Nephrology Quality Improvement And Artificial Intelligence (Aspn Qi/Ai) Interest Group
Ai-Powered Insights In Pediatric Nephrology: Current Applications And Future Opportunities., Arwa Nada, Yamen Ahmed, Jieji Hu, Darcy K. Weidemann, Gregory H. Gorman, Eva Glenn Lecea, Ibrahim A. Sandokji, Stephen Cha, Stella Shin, Salar Bani-Hani, Sai Sudha Mannemuddhu, Rebecca L. Ruebner, Aadil Kakajiwala, Rupesh Raina, Roshan George, Rim Elchaki, Michael L. Moritz, The American Society Of Pediatric Nephrology Quality Improvement And Artificial Intelligence (Aspn Qi/Ai) Interest Group
Manuscripts, Articles, Book Chapters and Other Papers
Artificial intelligence (AI) is rapidly emerging as a transformative force in pediatric nephrology, enabling improvements in diagnostic accuracy, therapeutic precision, and operational workflows. By integrating diverse datasets-including patient histories, genomics, imaging, and longitudinal clinical records-AI-driven tools can detect subtle kidney anomalies, predict acute kidney injury, and forecast disease progression. Deep learning models, for instance, have demonstrated the potential to enhance ultrasound interpretations, refine kidney biopsy assessments, and streamline pathology evaluations. Coupled with robust decision support systems, these innovations also optimize medication dosing and dialysis regimens, ultimately improving patient outcomes. AI-powered chatbots hold promise for improving patient engagement and adherence, while …
The Resilient Study: A Retrospective, Descriptive, Correlational Investigation Of Correlates Of Oral Endocrine Therapy Adherence In Older Women With Breast Cancer., Sunny Y. Ruggeri, Cynthia L. Russell Lippincott, Gregory L. Alexander, Rebecca J. Bartlett Ellis, Steven R. Chesnut, Lori A. Erickson
The Resilient Study: A Retrospective, Descriptive, Correlational Investigation Of Correlates Of Oral Endocrine Therapy Adherence In Older Women With Breast Cancer., Sunny Y. Ruggeri, Cynthia L. Russell Lippincott, Gregory L. Alexander, Rebecca J. Bartlett Ellis, Steven R. Chesnut, Lori A. Erickson
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Breast cancer is the most prevalent and costly cancer. Oral endocrine therapy (OET) improves survival rates and quality of life while reducing recurrence, mortality, morbidity, and medical costs. However, adherence to OET is challenging because OET is prescribed for 5-10 years. Determinants of OET nonadherence (NA) among women aged 65 and older remain poorly characterized. Existing studies are limited, often focusing on small, single-site samples and focusing on patient-level rather than multi-level determinants. Despite the unique needs of older women, research on OET-NA remains scarce.
OBJECTIVE: This study identified multi-level determinants of OET-NA in older women using ecological systems …
Targeted Epigenome Sequencing Of Eosinophils Reveals Cpg Sites And Regulatory Variants Associated With Asthma., Rébecca Dionne-Gagné, Anne-Marie Madore, Anne-Marie Boucher-Lafleur, Tomi Pastinen, Catherine Laprise
Targeted Epigenome Sequencing Of Eosinophils Reveals Cpg Sites And Regulatory Variants Associated With Asthma., Rébecca Dionne-Gagné, Anne-Marie Madore, Anne-Marie Boucher-Lafleur, Tomi Pastinen, Catherine Laprise
Manuscripts, Articles, Book Chapters and Other Papers
Eosinophils are pro-inflammatory cells that play a central role in asthmatic inflammation. However, few studies have examined their methylation profiles in asthma, all relying on microarray-based approaches. Here, an epigenome-wide association study in 183 purified eosinophil samples from the Saguenay-Lac-Saint-Jean asthma family cohort was performed using a custom sequencing panel targeting 4,609,564 CpGs in immune regulatory regions. Two CpG sites in MAEA and SLC9A2 genes, known to be involved in immune function, were significantly associated with asthma, while five additional sites showed suggestive associations. Integration with genotype data (7,829,429 variants) and expression counts (17,513 genes) identified significant quantitative trait loci-mediated …
Transparency And Accessibility In State Transportation Performance Reporting: A Systematic Examination Of State Department Of Transportation Websites Under Map-21, Jack Alan Klee
Dissertations
In the United States, all 50 State Departments of Transportation (DOTs) rely on federal funding as a key revenue source for roadway preservation programs. The 2012 Moving Ahead for Progress in the 21st Century (MAP-21) Act introduced a performance-based framework for transportation policy, establishing seven national goal areas that require state DOTs to report performance outcomes. As MAP-21 reaches its ten-year milestone, this dissertation investigates the extent to which state DOTs demonstrate transparency and accessibility in reporting federally mandated performance management results. Despite the centrality of performance reporting to accountability and public trust, systematic evaluations of these dimensions remain limited …
Barriers To Climate Change And Sustainability Action: Nursing Education And Practice, Dawn Marie Smith
Barriers To Climate Change And Sustainability Action: Nursing Education And Practice, Dawn Marie Smith
Dissertations
Climate change is one of the most pressing public health emergencies of our time and nurses can have a great impact in their current practice and in the education of future nurses (The Alliance of Nurses for Healthy Environments, n.d.; American Nurses Association, 2023; Health Care without Harm, 2025). Deaths due to rising temperatures, vector-borne illness, and food insecurity related to drought and extreme weather are on the rise (WHO, 2024). It has been estimated that globally over 250,000 additional deaths will be attributed to climate related effects between 2030 and 2050 (Watts et al., 2020; WHO, 2023).
A primary …
Convergence And Divergence Of Opinion About Treatment Of Binocular Vision Disorders Among Vision Care Professionals, Sonia Young
Convergence And Divergence Of Opinion About Treatment Of Binocular Vision Disorders Among Vision Care Professionals, Sonia Young
Dissertations
There are three distinct professions prominent in the field of pediatric vision care. They are ophthalmology, optometry and orthoptics. All professions are integral to the detection and treatment of pediatric binocular vision disorders. However, distinct schools of thought exist to describe the best approach to pediatric binocular vision disorders and their treatments. Literature often highlights two opposing schools of thought represented by the “medical” and “behavioral” approaches. While there is academic debate about the merits and pitfalls of either approach, there is a paucity of nuanced perspectives which more closely resemble the ways in which pediatric ocular clinicians approach diagnosis …
“The Thorns Of The Most Severe Virtue”: Education, Religion, And Cultural Power In Michigan, 1798–1855, Kyle Christopher Vanderwall
“The Thorns Of The Most Severe Virtue”: Education, Religion, And Cultural Power In Michigan, 1798–1855, Kyle Christopher Vanderwall
Dissertations
This project seeks to demonstrate the centrality of education and religion as cultural power levers used by Americans, Odawa, and Catholic missionaries. Though the power of each culture was uneven, efforts to create educational institutions imbued with different denominations of Christianity, as well as continued contestation over land, remade the cultures of all involved. Americans privileged state-building practices, the Odawa acculturated to remain in Michigan when removal policies were enacted throughout the United States, and the Catholic church attempted to proselytize Indigenous communities.
Although the ethnohistorical method needed to be understood in order to write this project, it is not …
Leading With Hope: A Clinical Communication Campaign To Promote Partner Hiv Testing In Assisted Partner Notification And Antenatal Care Programs In Uganda., Emily A. Hurley, Violet Gwokyala, Linda Kisaakye Nabitaka, Jolly Beyeza Kashesya, Mercylynn Agasha, Florence Namaganda, Nikolaus Schuetz, J Nalubega Ross, Joseph K B Matovu, Rhoda Wanyenze, Glenn Wagner, Kathy Goggin
Leading With Hope: A Clinical Communication Campaign To Promote Partner Hiv Testing In Assisted Partner Notification And Antenatal Care Programs In Uganda., Emily A. Hurley, Violet Gwokyala, Linda Kisaakye Nabitaka, Jolly Beyeza Kashesya, Mercylynn Agasha, Florence Namaganda, Nikolaus Schuetz, J Nalubega Ross, Joseph K B Matovu, Rhoda Wanyenze, Glenn Wagner, Kathy Goggin
Manuscripts, Articles, Book Chapters and Other Papers
Among heterosexual couples in sub-Saharan Africa, fears of relationship dissolution and inability to bear healthy children following an HIV-positive result remain barriers to HIV testing. Recently expanded availability of pre-exposure prophylaxis (PrEP) affords a critical opportunity to promote HIV testing with reassuring communication that highlights use for relationship preservation and healthy childbearing. We aimed to develop a theoretically-grounded communication intervention to promote partner HIV testing within assisted partner notification (APN) and antenatal care (ANC) programs in Uganda. Through an 18-month iterative co-creation process, we developed the HOPE Clinical Communication Campaign (HOPE-CCC) in collaboration with a project advisory board (PAB) of …
Promises, Pitfalls, And Paths Forward For The Pediatric Research Equity Act., Alexa L. Pagano, Danielle J. Green, Jennifer Goldman, Anjali Deshmukh
Promises, Pitfalls, And Paths Forward For The Pediatric Research Equity Act., Alexa L. Pagano, Danielle J. Green, Jennifer Goldman, Anjali Deshmukh
Manuscripts, Articles, Book Chapters and Other Papers
IMPORTANCE: Since its enactment in 2003, the Pediatric Research Equity Act (PREA) has significantly increased the number of pediatric drug studies performed and expanded pediatric drug labeling. Despite these advancements, many drugs used in children still lack pediatric-specific US Food and Drug Administration (FDA) labeling, even when pediatric studies are required by law. Recent legislative changes strengthened the FDA's enforcement authority over PREA. As these changes are implemented, persistent gaps in pediatric drug development warrant examination. Addressing these gaps may help ensure that children are systematically included in clinical research and that medications used in children are supported by rigorous …