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Utilising Plutonium Isotopes To Evaluate Soil Erosion In Tropical East African Agri-Systems, Sophia Marie Dowell Jan 2024

Utilising Plutonium Isotopes To Evaluate Soil Erosion In Tropical East African Agri-Systems, Sophia Marie Dowell

Other Faculty of Science and Engineering Theses

In the beautiful landscapes of Tropical East Africa, agriculture serves as the lifeblood of both people and ecosystems. The delicate balance between agriculture and soil preservation forms a complex web of factors that significantly impact soil and plant health in the region. The use of plutonium (Pu) isotopes is a potential strategy for unravelling the history of soil erosion in this ecologically varied and agriculturally crucial area. This thesis investigates a novel method using Pu isotopes to study small-scale soil redistribution patterns across various land use histories and management practices in the Rift Valley region of the Winam Gulf catchment …


An Examination Of The Degree To Which The Bia Models Representative Bureaucracy In Selected Lakota Communities, Melissa Eagle Bear Jan 2024

An Examination Of The Degree To Which The Bia Models Representative Bureaucracy In Selected Lakota Communities, Melissa Eagle Bear

Dissertations and Theses

This dissertation focuses on representative bureaucracy as it applies to the administration of the Bureau of Indian Affairs (BIA) and experienced by Lakota people within two Indian reservation communities. There is limited research on the theory and practice of representative bureaucracy within the context of BIA services. This qualitative study rests on the assumption that representative bureaucracy would lead to positive policy outcomes for Indian people. This research focuses on three specific areas of representative bureaucracy: passive, symbolic, and active representation. This phenomenological research takes as given the centrality of a Lakota epistemology: the beliefs, values and practices embodied in …


Online Perceived Social Support And Its Association With Psychopathology In Rural And Urban Youth, Ellen Alexandra Knowles Jan 2024

Online Perceived Social Support And Its Association With Psychopathology In Rural And Urban Youth, Ellen Alexandra Knowles

Dissertations and Theses

Social support is a fundamental aspect of development throughout adolescence. It has been found to buffer against the negative impacts of stress and provide general benefits to one’s well-being. Youth today are exposed to a range of opportunities for socialization with peers, both in-person and online, including interacting with others through texting, social media, video games, and other digital means. These online interactions have begun to be investigated as accessible methods through which adolescents can connect with others and maintain healthy relationships. Furthermore, digital social networks may be most critical for youth from isolated communities, including those from rural areas. …


Religious Upheaval In A South Dakota Mennonite Community, 1874-1940, Ryan Mews Jan 2024

Religious Upheaval In A South Dakota Mennonite Community, 1874-1940, Ryan Mews

Dissertations and Theses

In 1874, multiple colonies of German-Russian Mennonites and Hutterites entered the Dakota Territory to settle into tightknit religious communities. These Anabaptists sought to escape religious persecution and assimilation in Russia but found themselves influenced by American religious groups. Their history of isolationism caused these groups to draw lines between their congregations that kept them small but allowed them to interact with new ideas in different ways, but caused them to redefine their German Mennonite identity. One such influence erupted from the Presbyterian Church called fundamentalism that encouraged evangelical works in America and sought to combat modernism in religious institutions. In …


Implementation Of Formative Feedback Practices Via An Instructional Walkthrough Observation Tool: The Impact On Pre-Service Teacher Knowledge And Skills, Sheila Mulder Jan 2024

Implementation Of Formative Feedback Practices Via An Instructional Walkthrough Observation Tool: The Impact On Pre-Service Teacher Knowledge And Skills, Sheila Mulder

Dissertations and Theses

The collection of studies explores the role of feedback in the development of pre-service teachers’ knowledge and skills, focusing on the perspectives of university supervisors and cooperating teachers. The first study used a comparative case study examining pre-service teachers’ perceptions of the feedback they received and their ideal feedback across two universities. This revealed insights into effective feedback practices, informing teacher educator’s feedback practices, underscoring recommended feedback structures within teacher preparation programs. Moreover, there is a need for training in formative feedback practices to create a common understanding of the desired teaching practices, formative feedback practices to support collaborative feedback …


Mental Health In College Students: Efficacy Of A Telehealth-Delivered Occupational Therapy Program, Amy Marie Nelson Jan 2024

Mental Health In College Students: Efficacy Of A Telehealth-Delivered Occupational Therapy Program, Amy Marie Nelson

Dissertations and Theses

The number of college students in the United States struggling with mental health issues has increased tremendously over the past decade. Specifically, undergraduate students report stress and anxiety as significant inhibitors to academic performance. Colleges are investing resources to combat this problem, but increased counseling services are insufficient. Novel approaches beyond traditional college counseling services are recommended. Occupational therapy, not traditionally offered on most college campuses, may be one solution. A few occupational therapy programs exist on college campuses, but there is limited evidence of their efficacy, and most lack solid theoretical underpinnings. More evidence is needed on the effectiveness …


Childhood Maltreatment And Posttraumatic Stress Symptom Clusters: The Mediating Role Of Early Maladaptive Schemas, Sydney Nichole Stamatovich Jan 2024

Childhood Maltreatment And Posttraumatic Stress Symptom Clusters: The Mediating Role Of Early Maladaptive Schemas, Sydney Nichole Stamatovich

Dissertations and Theses

The current study tested a structural equation model to examine the associations between types of childhood maltreatment (i.e., neglect, punishment, and sexual abuse), Jeffrey Young’s early maladaptive schemas (EMSs), and posttraumatic stress disorder (PTSD) symptom clusters (i.e., avoidance, hyperarousal, intrusion, and negative alterations in cognitions and mood) in a sample of college students. Childhood maltreatment is a pervasive problem in the United States of America and has several short- and long-term physical and psychological consequences. Of note, victims of childhood maltreatment are at an elevated risk of developing PTSD. Further, childhood maltreatment and PTSD are associated with negative alterations in …


Crisis Intervention Model Effectiveness In South Dakota City And Rural Schools, Nicole Ann Bechen Jan 2024

Crisis Intervention Model Effectiveness In South Dakota City And Rural Schools, Nicole Ann Bechen

Dissertations and Theses

Little information is known on crisis prevention and intervention plans in schools across South Dakota. A review of the existent literature revealed gaps within school-based crisis intervention models, their objectives, and their effectiveness in addressing the psychological and physical safety needs of students, staff, teachers, families, and community members. Gaps in understanding rural crisis response were noted. The purpose of this study was to assess whether crisis prevention and intervention plans in South Dakota schools adequately protected students, staff, families, and community members. To achieve this, a stratified random sample of 53 PreK-12 public schools in the state of South …


Designing Fluorescent Moscs For Potential Applications In Illicit Drugs Detection, Robyn Nicole Cook Jan 2024

Designing Fluorescent Moscs For Potential Applications In Illicit Drugs Detection, Robyn Nicole Cook

Dissertations and Theses

Illicit and hazardous substances pose a serious effect on the human body which can create longer-term issues on the mental and physical health which potentially lead to fatalities. Current methods for detecting illicit substances include analytical techniques like mass spectrometry (MS) and gas/liquid chromatography (GC/LC) which are known for accuracy and sensitivity. However, these instruments are bulky, costly, time-consuming, and require highly trained personnel. An alternative approach to overcoming these limitations is to employ nanostructured molecule-based chemical sensing technologies that are user-friendly, portable, and cost-effective with the sensitivity for detecting illicit substances. One such candidate is metal-organic super-containers (MOSCs), which …


Developing An Occupation-Based Complex Intervention For Living Well With Anxiety In Parkinson's (Obtain-Pd), Christopher Lovegrove Jan 2024

Developing An Occupation-Based Complex Intervention For Living Well With Anxiety In Parkinson's (Obtain-Pd), Christopher Lovegrove

School of Health Professions Theses

Background: Parkinson’s is the UK's second most common neurodegenerative condition, affecting approximately 175,000 people. Current anxiolytic medications are ineffective in treating anxiety in Parkinson’s. The most promising behavioural interventions have inconclusive and mixed results. Occupational therapy is effective at promoting participation in activities of daily living and is recommended in national guidelines. An evidence-based occupational therapy intervention for living well with anxiety in Parkinson’s does not exist.Aim: To design a new occupation-based complex intervention for living well with anxiety in Parkinson’s (OBtAIN-PD) in co-production with people with Parkinson’s (PWPs), care partners, and occupational therapists.Methods: A scoping review, conducted in line …


Sensing Freedom: An Occupational Therapy And Service User Perspective Of Sensory Processing And Occupational Participation In Forensic Mental Health, Elanor Moore Jan 2024

Sensing Freedom: An Occupational Therapy And Service User Perspective Of Sensory Processing And Occupational Participation In Forensic Mental Health, Elanor Moore

School of Health Professions Theses

Abstract: Elanor Moore: Sensing Freedom: An Occupational Therapy and Service User Perspective of Sensory Processing and Occupational Participation in Forensic Mental HealthBackground: Sensory processing is a universal dynamic mind-body process which all individuals experience. It is influenced by the environment and impacts participation in occupations. Occupational therapists in forensic mental health inpatient settings aim to facilitate occupationally enriching opportunities, to support service users’ safe community reintegration. Emerging evidence indicates links between sensory processing and mental health, but with limited guidance on how this translates into occupation-focused practice.Methodology: A scoping review identified both inconsistency in sensory processing terminology and a limited …


Exploring The Links Between Unknowns, Uncertainty And Epistemological Understanding In A More Authentic Form Of School Science Investigation, Matthew Wharf Jan 2024

Exploring The Links Between Unknowns, Uncertainty And Epistemological Understanding In A More Authentic Form Of School Science Investigation, Matthew Wharf

Other Faculty of Arts, Humanities and Business Theses

This research explored the role a more ‘authentic’ science investigation had on the epistemological understanding of secondary school students. It reviewed the understanding of what is taught within the science curriculum in terms of epistemology and the Nature of Science (NOS) and what may be considered a more authentic activity that more closely aligns with the qualities of professional science, where new knowledge is being formed as compared to what could be seen as conventional science investigations, the repetition of classic experiments. Lessons of 3 different classes, at different schools and in different years were used. An investigation lesson from …


The Assessment-Related Logics Of Practice At A South West Multi-Academy Trust, Samuel Gordon Morahan Jan 2024

The Assessment-Related Logics Of Practice At A South West Multi-Academy Trust, Samuel Gordon Morahan

Plymouth Institute of Education Theses

Over the last 40 years there have been widescale changes to the British education system. Through the process of neoliberalisation, education has become a commodity to be bought and sold with an ever-increasing emphasis on performativity and its related measures. Within this educational market, alternative provision settings provide commissioning schools with opportunities to purchase placements and packages for pupils, who for a variety of reasons, are unable to engage in mainstream education. Alternative provision settings must evidence value for money to these schools, whilst meeting statutory inspection requirements. Assessment practices and the numerical data they generate are central within this …


Athletic Trainer's Perceptions Of And Experiences With Professional Development Approaches For Enhancing Clinical Documentation, Sarah L. Nottingham, Tricia M. Kasamatsu, Julie M. Cavallario, Cailee E. Welch Bacon Jan 2024

Athletic Trainer's Perceptions Of And Experiences With Professional Development Approaches For Enhancing Clinical Documentation, Sarah L. Nottingham, Tricia M. Kasamatsu, Julie M. Cavallario, Cailee E. Welch Bacon

Rehabilitation Sciences Faculty Publications

Context

Little is known about how athletic trainers (ATs) learn clinical documentation, but previous studies have identified that ATs have a need for more educational resources specific to documentation.

Objective

To obtain ATs' perspectives on learning clinical documentation.

Design

Qualitative study.

Setting

Web-based audio interviews.

Patients or Other Participants

Twenty-nine ATs who completed 2 different continuing education (CE) clinical documentation modules. Participants averaged 36.2 ± 9.0 years of age and included 16 women and 13 men representing 21 US states and 8 clinical practice settings.

Data Collection and Analysis

Participants were recruited from a group of ATs who completed 1 …


Assessing Discharge Knowledge For Caregivers Of Newborn (Using Video Discharge Instructions As An Adjunct To Standard Written Instructions) In Covid Period – A Randomized Controlled Trial, Jayesh Yadav, Khyati Gupta, Vishal D. Sawant Jan 2024

Assessing Discharge Knowledge For Caregivers Of Newborn (Using Video Discharge Instructions As An Adjunct To Standard Written Instructions) In Covid Period – A Randomized Controlled Trial, Jayesh Yadav, Khyati Gupta, Vishal D. Sawant

Digital Journal of Clinical Medicine

Background: Studies have demonstrated that caregivers of newborn frequently face challenges in comprehending the instructions provided to them upon discharge. Video discharge instructions provide a clear and concise message and can potentially alleviate factors which have an impact on comprehension of caregivers like illiteracy, communication barriers and limited physician time. We aim to assess the impact of incorporating video-based discharge instructions on caregivers' comprehension of newborn care and post-discharge follow-up, specifically in the context of the COVID-19 pandemic.

Methods: Caregivers of newborn in the COVID times were randomized into written only and written with video discharge instruction groups; …


The Leadership Blind Spot: Why Are Black Boys Missing From The School’S Leadership Positions?, Chima Ikeme Jan 2024

The Leadership Blind Spot: Why Are Black Boys Missing From The School’S Leadership Positions?, Chima Ikeme

Theses and Dissertations

The purpose of this phenomenological action research study was to explore the factors that have contributed to the absence of Black boys in school leadership positions. The study looked to answer the following research questions: How do Black male students perceive leadership and their connection to leadership roles on campus? What barriers exist that discourage or prohibit Black boys from engaging in school organization student leadership positions? How can student leadership from Black boys on campus be increased?Critical Race Theory, Transformational Leadership Theory, and Self Determination Theory served as the theoretical frameworks that grounded this study. Utilizing a qualitative approach …


Using Feature Selection Enhancement To Evaluate Attack Detection In The Internet Of Things Environment, Khawlah Harahsheh, Rami Al-Naimat, Chung-Hao Chen Jan 2024

Using Feature Selection Enhancement To Evaluate Attack Detection In The Internet Of Things Environment, Khawlah Harahsheh, Rami Al-Naimat, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

The rapid evolution of technology has given rise to a connected world where billions of devices interact seamlessly, forming what is known as the Internet of Things (IoT). While the IoT offers incredible convenience and efficiency, it presents a significant challenge to cybersecurity and is characterized by various power, capacity, and computational process limitations. Machine learning techniques, particularly those encompassing supervised classification techniques, offer a systematic approach to training models using labeled datasets. These techniques enable intrusion detection systems (IDSs) to discern patterns indicative of potential attacks amidst the vast amounts of IoT data. Our investigation delves into various aspects …


Perceptions About Catholic High School Athletics, Kevin J. Calkins Jan 2024

Perceptions About Catholic High School Athletics, Kevin J. Calkins

Journal of Catholic Education

In the largest survey to date on Catholic school identity in athletics (49 U.S. States, n = 2273), administrators, counselors, and teachers responded to a survey about the perceived value of interscholastic athletics, school support of athletics, the contribution of coaches to school mission, Catholic identity in athletics, and the importance of the school’s athletic director and coaches to have a mission orientation. The results of the study indicate that administrators, counselors, and teachers have positive perceptions of Catholic high school athletics. Teacher perceptions differed more than administrators and counselors based on their age, gender, and religion. At least one …


Faith And Stem Education: A Path To Mutual Elevation In Catholic Schools, Michael Szopiak, Matthew Kloser Jan 2024

Faith And Stem Education: A Path To Mutual Elevation In Catholic Schools, Michael Szopiak, Matthew Kloser

Journal of Catholic Education

Amidst increasing religious disaffiliation, often due to a perceived tension between faith and the STEM disciplines, Catholic schools provide critical opportunities for young people to recognize how these domains can be mutually elevating. The field, however, lacks guidance as to how this integration should occur in practice. This conceptual paper first provides an overarching framework for how aspects of the Catholic tradition, like Scripture and the Catholic social tradition, can shape traditional educational domains of STEM teaching and learning. Secondly, we provide a heuristic of three criteria for deeply engaging students at the interface of the Catholic faith and the …


Increasing Parent Faith Engagement At A Parish School, Grace Mazza Urbanski Jan 2024

Increasing Parent Faith Engagement At A Parish School, Grace Mazza Urbanski

Journal of Catholic Education

Increasing faith engagement among Catholic school shareholders is a priority for school leaders. Catholic school communities can learn from this year-long project with a parish school. Sacred Heart Parish School serves approximately 300 K3-8th grade students. Like many parish schools, Sacred Heart sees a growing number of parents disengaged with the faith life of the parish and school, despite 98% of them being registered parishioners. The parent population enjoys robust and regular social activities, but report they are uncomfortable or uninterested in faith activities. The mission of Sacred Heart Parish School is to nurture “children’s growth in the Catholic faith,” …


Paschal Space Of Healing And Community: An Affinity Group For Catholic School Teachers Of Color, John L. Beltramo, Lisa Archuleta Jan 2024

Paschal Space Of Healing And Community: An Affinity Group For Catholic School Teachers Of Color, John L. Beltramo, Lisa Archuleta

Journal of Catholic Education

As Catholic schools seek to recruit and retain more ethnoracially diverse faculties, we examine one site of potential support for Catholic school teachers of color – a racial affinity group. Using critical research methodology with qualitative data collection, we studied five teachers of color who engaged in weekly affinity group meetings, which were structured as Freirian culture circles and ran over a period of five months. Using a Catholic, critical framework on teacher education, we analyzed the data (culture circle recordings, written reflections, baseline and comparative interviews, along with classroom observations and debriefs) to examine how teachers’ participation impacted their …


Augustinian Composition Pedagogy And The Catholic Liberal Arts In The Time Of Generative Ai, Gavin F. Hurley Jan 2024

Augustinian Composition Pedagogy And The Catholic Liberal Arts In The Time Of Generative Ai, Gavin F. Hurley

Journal of Catholic Education

This article proposes a theoretical basis of Augustinian composition pedagogy by tracing the symbiotic relationship between writing and knowing found within St. Augustine’s Letters, The Trinity, Soliloquies, and Confessions and connecting them to modern writing-to-learn composition pedagogies. Given today’s trying times of generative AI, this article argues that Catholic schools revitalize the writing arts in a manner proposed by Augustine—that is, to enrich inward contemplation and outward love for others. In embracing such philosophy of writing and applying it across the disciplines, Catholic schools can enrich their distinctively Catholic liberal arts mission—and ward off dangers found in …


Is The Job Performance Of Tourism Academicians Related To Their Emotional Intelligence?, Leyla Tokgöz, Zennube Işık, Mehmet Fatih Işık Jan 2024

Is The Job Performance Of Tourism Academicians Related To Their Emotional Intelligence?, Leyla Tokgöz, Zennube Işık, Mehmet Fatih Işık

Khazar Journal of Humanities and Social Sciences

The aim of the research is to determine whether the job performances of tourism academics in Türkiye are related to emotional intelligence. Further, this research is an endeavor to investigate whether emotional intelligence and job performance differ according to demographic variables. “Job Performance Scale” adapted by Yang and Hwang (2014) was used to measure the job performance of academicians. In addition to that “Rotterdam Emotional Intelligence Scale” developed by Pekaar, Bakker, Linden, and Born (2017) and adapted to Turkish by Tanrıöğen and Türker (2019) was used to measure their emotional intelligence. The research sample consists of academicians working in Tourism …


A Novel Hyperparameter Search Approach For Accuracy And Simplicity In Disease Prediction Risk Scoring, Yajun Lu, Thanh Duong, Zhuqi Miao, Thanh Thieu, Jivan Lamichhane, Abdulaziz Ahmed, Durdun Delen Jan 2024

A Novel Hyperparameter Search Approach For Accuracy And Simplicity In Disease Prediction Risk Scoring, Yajun Lu, Thanh Duong, Zhuqi Miao, Thanh Thieu, Jivan Lamichhane, Abdulaziz Ahmed, Durdun Delen

Research, Publications & Creative Work

Objective: Develop a novel technique to identify an optimal number of regression units corresponding to a single risk point, while creating risk scoring systems from logistic regression-based disease predictive models. The optimal value of this hyperparameter balances simplicity and accuracy, yielding risk scores of small scale and high accuracy for patient risk stratification.

Materials and Methods: The proposed technique applies an adapted line search across all potential hyperparameter values. Additionally, DeLong test is integrated to ensure the selected value produces an accuracy insignificantly different from the best achievable risk score accuracy. We assessed the approach through two case studies predicting …


Igamt: Privacy-Preserving Electronic Health Record Synthesization With Heterogeneity And Irregularity, Wenjie Wang, Pengfei Tang, Jian Lou, Yuanming Shao, Lance Waller, Yi-An Ko, Li Xiong Jan 2024

Igamt: Privacy-Preserving Electronic Health Record Synthesization With Heterogeneity And Irregularity, Wenjie Wang, Pengfei Tang, Jian Lou, Yuanming Shao, Lance Waller, Yi-An Ko, Li Xiong

Faculty, Staff and Student Publications

Utilizing electronic health records (EHR) for machine learning-driven clinical research has great potential to enhance outcome predictions and treatment personalization. Nonetheless, due to privacy and security concerns, the secondary use of EHR data is regulated, constraining researchers’ access to EHR data. Generating synthetic EHR data with deep learning methods is a viable and promising approach to mitigate privacy concerns, offering not only a supplementary resource for downstream applications but also sidestepping the privacy risks associated with real patient data. While prior efforts have concentrated on EHR data synthesis, significant challenges persist: addressing the heterogeneity of features including temporal and non-temporal …


Federated Node Classification Over Distributed Ego-Networks With Secure Contrastive Embedding Sharing, Han Xie, Li Xiong, Carl Yang Jan 2024

Federated Node Classification Over Distributed Ego-Networks With Secure Contrastive Embedding Sharing, Han Xie, Li Xiong, Carl Yang

Faculty, Staff and Student Publications

Federated learning on graphs (a.k.a., federated graph learning- FGL) has recently received increasing attention due to its capacity to enable collaborative learning over distributed graph datasets without compromising local clients' data privacy. In previous works, clients of FGL typically represent institutes or organizations that possess sets of entire graphs (e.g., molecule graphs in biochemical research) or parts of a larger graph (e.g., sub-user networks of e-commerce platforms). However, another natural paradigm exists where clients act as remote devices retaining the graph structures of local neighborhoods centered around the device owners (i.e., ego-networks), which can be modeled for specific graph applications …


Rural Racial Disparities And Barriers In Mammography Utilization Among Medicare Beneficiaries In Texas: A Longitudinal Study, Zhaoli Liu, Yong Shan, Yong-Fang Kuo, Sharon H Giordano Jan 2024

Rural Racial Disparities And Barriers In Mammography Utilization Among Medicare Beneficiaries In Texas: A Longitudinal Study, Zhaoli Liu, Yong Shan, Yong-Fang Kuo, Sharon H Giordano

Faculty, Staff and Student Publications

This study examined rural racial/ethnic disparities in long-term mammography screening practices among Medicare beneficiaries. A retrospective longitudinal study was conducted using 100% Texas Medicare data for women aged 65-74 who enrolled in Medicare between 2010-2013. Of the 114,939 eligible women, 21.2% of Hispanics, 33.3% of non-Hispanic Blacks (NHB), and 38.4% non-Hispanic Whites (NHW) in rural areas were regular users of mammography, compared to 33.5%, 44.9%, and 45.3% of their counterparts in urban areas, respectively. Stratification analyses showed rural Hispanics and NHB were 33% (95% CI, 25% - 40%) and 22% (95% CI, 6% - 36%) less likely to be regular …


A Brief But Comprehensive Three-Item Social Connectedness Screener For Use In Social Risk Assessment Tools, Nancy P Gordon, Matthiew C Stiefel Jan 2024

A Brief But Comprehensive Three-Item Social Connectedness Screener For Use In Social Risk Assessment Tools, Nancy P Gordon, Matthiew C Stiefel

Faculty, Staff and Student Publications

BACKGROUND: The 2014 IOM report "Capturing Social and Behavioral Domains and Measures in Electronic Health Records" described three subdomains of social relationships that affect patient health and well-being. However, most social risk screeners currently assess only one subdomain, frequency of social connections. We are proposing a three-item Brief Social Connectedness (SC) screener that additionally assesses risks in social/emotional support and loneliness/social isolation subdomains.

METHODS: For this cross-sectional study, we used data from a 2021 Kaiser Permanente Northern California (KPNC) social risk survey for 2244 members ages 35-85 years. The survey included three validated questions that covered the SC subdomains (frequencies …


Risk Stratification And Prediction Of Severity Of Covid-19 Infection In Patients With Preexisting Cardiovascular Disease, Stanislava Matejin, Igor D Gregoric, Rajko Radovancevic, Slobodan Paessler, Vladimir Perovic Jan 2024

Risk Stratification And Prediction Of Severity Of Covid-19 Infection In Patients With Preexisting Cardiovascular Disease, Stanislava Matejin, Igor D Gregoric, Rajko Radovancevic, Slobodan Paessler, Vladimir Perovic

Faculty, Staff and Student Publications

Introduction: Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is a highly contagious viral disease. Cardiovascular diseases and heart failure elevate the risk of mechanical ventilation and fatal outcomes among COVID-19 patients, while COVID-19 itself increases the likelihood of adverse cardiovascular outcomes.

Methods: We collected blood samples and clinical data from hospitalized cardiovascular patients with and without proven COVID-19 infection in the time period before the vaccine became available. Statistical correlation analysis and machine learning were used to evaluate and identify individual parameters that could predict the risk of needing mechanical ventilation and patient survival.

Results: Our results confirmed that COVID-19 …


On The Relative Conservativeness Of Bayesian Logistic Regression Method In Oncology Dose-Finding Studies, Cheng-Han Yang, Guanghui Cheng, Ruitao Lin Jan 2024

On The Relative Conservativeness Of Bayesian Logistic Regression Method In Oncology Dose-Finding Studies, Cheng-Han Yang, Guanghui Cheng, Ruitao Lin

Faculty, Staff and Student Publications

The Bayesian logistic regression method (BLRM) is a widely adopted and flexible design for finding the maximum tolerated dose in oncology phase I studies. However, the BLRM design has been criticized in the literature for being overly conservative due to the use of the overdose control rule. Recently, a discussion paper titled "Improving the performance of Bayesian logistic regression model with overall control in oncology dose-finding studies" in Statistics in Medicine has proposed an overall control rule to address the "excessive conservativeness" of the standard BLRM design. In this short communication, we discuss the relative conservativeness of the standard BLRM …