Digital Commons Network^™

Pfas Toxicity: What’S True, What’S Not, And What Really Matters, Jamie C. Dewitt, Ian T. Cousins, Gretta Goldenman, Dorte Herzke, Rainer Lohmann, Mark Miller, Carla A. Ng, Martin Scheringer, Xenia Trier, Zhanyun Wang

Graduate School of Oceanography Faculty Publications

A substantial body of evidence exists demonstrating that exposure to per- and polyfluoroalkyl substances (PFASs) poses a risk to human health. Data from epidemiological studies of those exposed occupationally or environmentally demonstrate adverse health risks, and these health effects are concordant with data from toxicological studies. Systematic reviews, conducted by agencies, organizations, and independent scientists that synthesize and integrate these data streams, have concluded that a range of health risks arise from PFAS exposure, including different types of cancer, especially kidney and testicular cancer, metabolic alterations such as increased liver enzymes and increased cholesterol, immune dysfunction such as reduced vaccination …

Ndls Communicator: Week Of 05.18.26, Notre Dame Law School

NDLS Communicator

The Latest News

• Commencement Features
• Notre Dame Law graduate Garrett Hofmann selected for FASPE Ethics Fellowship
• Syl and Vicki Schieber Make Generous Gift to Support Death Penalty Abolition Week at Notre Dame Law School for Five Years

Student News

• Perla Khattar, J.S.D. candidate

Faculty Briefs

• Susan Azyndar
• Msgr. John Paul Kimes
• James Seckinger
• Barry Cushman
• G. Marcus Cole
• Carter Snead
• Nicole Garnett & 3L, Jimmy Murphy
• Roger Alford
• Paul Miller
• Diane Desierto
• Frederick Mostert & Alexandria Noble '26 J.D.
• G. Robert Blakey

Events

• All Staff Meeting

Around the Watercooler

• Kresge Law Library Celebrates 40th Anniversary as a participant in the …

Sociedad Concesionaria Metropolitana De Salud S.A. V. Webuild S.P.A

2026 Decisions

USDC for the District of Delaware

Esg-Based Litigation: A Solution To Social Media Companies’ Immunization From Liability For Human Trafficking On Their Platforms, Grace Dore

Brooklyn Journal of Corporate, Financial & Commercial Law

Social media platforms have transformed communication, but they have also become a critical tool for human traffickers, who use them to recruit victims, maintain control, and facilitate illegal activities. Despite this, social media companies have largely avoided legal accountability due to the broad immunity provided by Section 230 of the Communications Decency Act (“CDA”), which courts have interpreted to shield platforms from lawsuits arising from user activity. Congress has sought to address this gap through legislation such as the Trafficking Victims Protection Act (“TVPA”) and the Allow States and Victims to Fight Online Sex Trafficking Act (“FOSTA”). However, these efforts …

Regulatory Whiplash: The Sec’S Proxy Advisor Reversal And A Delaware-Inspired Sliding Scale Framework For Judicial Review, Alexandra Pellegrino

Brooklyn Journal of Corporate, Financial & Commercial Law

The Securities and Exchange Commission’s 2020 regulation of proxy advisory firms, and its abrupt 2022 recission, triggered a consequential circuit split that exposes a deeper tension in administrative law: how courts should review agency reversals in regulatory environments where stability and adaptability are both essential. In National Association of Manufacturers v. Securities Exchange Commission, the Fifth Circuit invalidated the recission for failing to adequately address reliance interests and prior factual findings. In contrast, the Sixth Circuit in Chamber of Commerce v. Securities Exchange Commission upheld the agency’s reversal under a more deferential interpretation of Federal Communications Commission v. Fox Television …

From Code To Calm: Cold Debriefing And Spiritual Sessions For Icu Nurses, Cailin Ford Bsn, Rn-Bc, Va-Bc, Taryn Sheehy Bsn, Rn, Ccrn, Julie Mackenzie Msn, Rn Agcns, Jeanne Hlebichuk

Nursing

Debriefing after critical events promotes communication, teamwork, and performance improvement. Concurrently, a positive spiritual climate is also linked to improved teamwork and safety climates, as well as reducing RN intent to leave and turnover (Celano et al., 2022). Clinical RNs engaged with professional governance identified an opportunity to expand on a nurse-led hot debriefing project and incorporate a second phase consisting of cold and spiritual debriefing. In this second phase, cold and spiritual debriefing was piloted in a 30-bed cardiovascular ICU, staffed with 110 RNs. First, standard cold debriefing materials were developed with organization specific resources. Two RN project leads …

Optimization And Energy Efficiency Analysis Of An Automatic Feed Mixer With A Rotating Drum Mechanism, Kris Witono, Talifatim Machfuroh, Nurlia Pramita Sari, Lisa Agustriyana, Aini Lostari

Journal of Mechanical Engineering Science and Technology (JMEST)

Energy-efficient feed mixer machines are important for improving the productivity and sustainability of small and medium-scale livestock farms. Previous studies primarily focused on either structural performance or mixing efficiency, with limited studies integrating both aspects. Therefore, this study evaluated an automatic rotating-drum feed mixer by combining Finite Element Method (FEM) analysis and energy modeling. The study used FEM simulations for different materials, namely A36 steel alloy, stainless steel 304, aluminium 6061, and galvanized steel, with thicknesses of 3 mm and 4 mm, as well as different drum systems. The FEM results showed that all evaluated materials met the minimum safety …

Supported Storytelling Through The ‘Life Threads’ Approach For Family Members After Traumatic Brain Injury: “We've Been Through All Of This Trauma, And You're Giving Me Some String?, Alyson Norman

School of Psychology

Traumatic brain injury (TBI) brings inevitable and significant changes for family members, yet there is little to relieve their trauma, resolve their grief, or prevent ongoingsuffering. The aim of this qualitative pre-feasibility study was to understand theclinical potential of storytelling for families after TBI using the ‘Life Threads’ approach(LTA). An in-depth inductive qualitative design was adopted within an interpretivist paradigm. Following informed consent, participants took part in an online focusgroup, then engaged with the LTA over four weeks before completing an unstructured, in-person interview. A final focus group explored participants’ reflections on theLTA. A purposive sample of 20 family members …

Early Neurodevelopmental Outcomes In A Child With Tuberous Sclerosis Complex Treated With Everolimus And Vigabatrin, Sarah Ml Wilson, Megan Samuels, Luana Pimentel, Shelley Varnado, Claire Sartwell, Rosleen Mansour, Deborah Pearson, Hope Northrup, Mary Kay Koenig

Faculty, Staff and Student Publications

Objectives: To report early neurodevelopmental outcomes in a child with Tuberous Sclerosis Complex (TSC) treated with everolimus and vigabatrin.

Methods: The authors report a five-year-old girl with Tuberous Sclerosis Complex who was initiated on vigabatrin at seven weeks old to treat infantile spasms and on everolimus at two months of age to treat a subependymal giant cell astrocytoma. Neuropsychological assessments were conducted in this patient at 12, 24, and 36 months using the Bayley-III and Vineland-II.

Results: On the Bayley-III, the patient had a high average cognitive composite score at 12 months and a high average language composite score at …

Medical Monitoring Working Group Meeting Minutes, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

The Impact Of Tgfβ Conditioning And Socs3 Expression On Cytokine Signal Transduction And Inflammatory Gene Expression In Fibroblasts, Morgan Anderson-Crannage

NYMC Student Theses and Dissertations

Inflammation is a major driver in many aspects of recessive dystrophic epidermolysis bullosa (RDEB) pathology, including impaired wound healing, fibrosis, and potentially cutaneous squamous cell carcinoma development. Fibroblasts, as key stromal cells in the dermis, are responsible for orchestrating inflammatory responses through the secretion of cytokines and chemokines upon stimulation with IL-1α or IL-6. Suppressor of Cytokine Signaling 3 (SOCS3) functions as a negative feedback regulator of cytokine signaling and has emerged as a key modulator of inflammatory responses in immune cells and fibroblasts. Transforming Growth Factor Beta (TGFβ), a known driver of fibrosis in RDEB, has been implicated in …

The Heterogeneous Response Of Astrocytes In Different Brain Regions Under Metabolic Stress, Pawan Kumar Thapaliya

USF Tampa Graduate Theses and Dissertations

Astrocytes play a central role in maintaining ionic homeostasis, neurotransmitter clearance, and brain en-ergy metabolism. Their excitability, reflected in activity-evoked intracellular sodium (Na+, [Na+]i) and calcium (Ca2+,[Ca+]i) dynamics, is increasingly recognized as a critical determinant of neuronal function and vulnerability, particularly under metabolic stress. Despite their importance, the mechanisms underlying astrocytic ionic signaling and its regional heterogeneity remain incompletely understood. In this thesis, I developed detailed computational and biophysical models to investigate astrocytic Na+ and Ca2+ dynamics, their bioenergetic consequences, and the roles of key ion transporters under physiological and metabolically stressed conditions, validating the models against experi- mental data. …

Decoding Spatial Transcriptomics Across Multicellular And Subcellular Resolutions, Chongyue Zhao, Hanqiu Zhao, Zhiyu Dai, Et Al.

2020-Current year OA Pubs

Current whole-genome spatial transcriptomics (ST) platforms, which range from multicellular (e.g., Visium) to subcellular resolution (e.g., Visium HD, Stereo-seq), face significant challenges in accurately decomposing or aggregating spots into single cells-the fundamental units of biological activity. To date, most existing computational methods operate at the spot level, and no method has effectively reconstructed transcriptomes at single-cell resolution. In this study, we present STARS (Spatial Transcriptomics across Resolutions for Single Cells). Leveraging Vision Transformer model and contrastive learning, STARS combines high-resolution histology images with spot-level transcriptomics data to reconstruct single-cell-level gene expression from multicellular and subcellular platforms. We demonstrate the advantage …

Golden Hour Open Conceptual Architecture For Citizen-Initiated Structured Urgency Signaling, Jaime Gerardo Figoni Him

Defensive Publications Series

Abstract

Golden Hour proposes a minimalist, open, and low-bandwidth emergency signaling architecture that enables citizens to transmit structured urgency information during the critical first hour of a disaster. The system combines a single-tap severity code (Red / Yellow / Green), a brief guided question sequence, and resilient transmission paths to create a live, color-coded situational heat map for emergency responders.

By treating emergency response as a physics problem of controlling informational entropy, Golden Hour enables a near-instantaneous reduction in chaos while fostering voluntary human solidarity. The system is designed as a complement to, not a replacement for, existing emergency services.

Associations Between Perceptions Of Indoor Environmental Quality And Satisfaction With Life Among Residents In Saudi Arabia, Hatim M. Badri, Wahaj A. Khan, Mohammad N. Shah, Osama A. Banah, Mohamed Osman Elamin, Rakan Ekram, Rayan Khayat, Abdullah Muhammad Alzhrani, Baraa Sami Quronfulah, Muath Ahmed Aldomini

Journal of Health Research

Background: Indoor residential environments influence physical and mental health, but evidence linking perceived Indoor Environmental Quality (IEQ) to Satisfaction With Life (SWL) in Saudi Arabia is limited. This study explored residents’ perceptions of IEQ and its association with SWL.

Methods: A cross-sectional online survey (March–April 2025) was conducted among adults (≥18 years) in Saudi Arabia using convenience sampling. A total of 451 participants completed a structured questionnaire. Data were analysed using descriptive statistics, Pearson correlations, one-way ANOVA, and multivariable logistic regression to identify IEQ predictors of low SWL (≤20), adjusting for age, sex, and BMI.

Results: …

Caregiving Experiences And Challenges Among Caregivers Of Children With Epilepsy In Thailand: A Qualitative Study, Arthittaya Kaenkrai, Pramote Thangkratok, Pawanrat Panjatharakul, Apasri Lusawat, Moritz Tacke

Journal of Health Research

Background: Childhood epilepsy requires long-term management and places substantial responsibilities on caregivers. In Thailand, limited public awareness and persistent stigma surrounding epilepsy may intensify caregivers’ psychosocial and practical burdens. This study aimed to explore the lived experiences of caregivers of children with epilepsy in Thailand.

Methods: A qualitative study using two semi-structured focus group discussions (FGDs; 5 participants per group) and 15 in-depth interviews (IDIs) was conducted with primary caregivers of children with epilepsy receiving care at a neurological referral institute in Thailand. Participants were purposively selected to capture a diverse range of caregiving experiences. Data were audio-recorded, transcribed verbatim, …

Hak Cipta Bukan Hanya Copyright, Agus Sardjono

Jurnal Hukum & Pembangunan

Abstract

Anallsis Terhadap Kontroversi Rancangan Peraturan Pemerintah Tentang Tata Cara Intersepsi Yang Sesuai Hukum (Lawful Interception), Edmon Makarim

Jurnal Hukum & Pembangunan

Abstract

The Necessity Of Capacity Building For Indonesia's Effective Utilization Of Wto Dispute Settlement Mechanism: Implementation Of Gait Article Xx For Trade And Environment Issues, Windu Kisworo

Jurnal Hukum & Pembangunan

Abstract

Analisa Law And Economics Atas Kompensasi Dan Asuransi Lingkungan Di Indonesia: Sebuah Kritik Atas Kompensasi Tanpa Sistem, Andri Gunawan Wibisana, Pramita K. Putri

Jurnal Hukum & Pembangunan

Abstract

Millennials On The Move: Exploring The Importance Of Sustainability, Kimberly Mcneil, George Stone

Atlantic Marketing Association Proceedings

No abstract provided.

Franchisee Performance: A Signaling Perspective, Swati Panda, Audhesh Paswan

Atlantic Marketing Association Proceedings

No abstract provided.

Marketing College Football In The “New Normal”, Chris Croft, Tim Wilson

Atlantic Marketing Association Proceedings

No abstract provided.

An Investigation Of Key Factors In Promoting A New Collegiate Recreation Facility: If You Build It - Will They Come?, Paul J. Costanzo, Cynthia P. Costanzo

Atlantic Marketing Association Proceedings

No abstract provided.

Case: When Free Is Too Much To Pay, Rebecca Burcham

Atlantic Marketing Association Proceedings

No abstract provided.

Selling In The Digital Era: The Power Of Artificial Intelligence, George Morrone Iv, Monica Wei, Rex Mcclure

Atlantic Marketing Association Proceedings

No abstract provided.

Adoption And Diffusion Of At-Home Medical Tests, Jerome Christia

Atlantic Marketing Association Proceedings

No abstract provided.

Do The Effects Of Ethnocentrism And Cosmopolitanism Depend On Countries-Of-Origins? A Study Of U.S. Consumers, Thomas Tanner, Ronda Mariani

Atlantic Marketing Association Proceedings

No abstract provided.

Validation Of Entrepreneurial Marketing Dimensions In North Carolina Wineries, G. David Shows, James Stoddard, Pia A. Albinsson

Atlantic Marketing Association Proceedings

No abstract provided.

The Use Of Music In Retro Branding, Jon Littlefield, Cortnee Young

Atlantic Marketing Association Proceedings

No abstract provided.