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Report To The American Ornithologists' Union By The Committee On Bird Protection, 1958, The Auk Sep 2024

Report To The American Ornithologists' Union By The Committee On Bird Protection, 1958, The Auk

The Auk

No abstract provided.


Contribution To The Life History Of The Swallow-Tanager, Ernst Schaefer Sep 2024

Contribution To The Life History Of The Swallow-Tanager, Ernst Schaefer

The Auk

No abstract provided.


Obituaries, The Auk Sep 2024

Obituaries, The Auk

The Auk

No abstract provided.


Allan Brooks, 1869-1946, Hamilton M. Laing Sep 2024

Allan Brooks, 1869-1946, Hamilton M. Laing

The Auk

No abstract provided.


Duck Weights In Illinois, Frank C. Bellrose, Arthur S. Hawkins Sep 2024

Duck Weights In Illinois, Frank C. Bellrose, Arthur S. Hawkins

The Auk

No abstract provided.


In Memoriam: Joseph Grinnell, Jean M. Linsdale Sep 2024

In Memoriam: Joseph Grinnell, Jean M. Linsdale

The Auk

No abstract provided.


The Ornithological Journals, The Auk Sep 2024

The Ornithological Journals, The Auk

The Auk

No abstract provided.


Dr Shufeldt's Bibliography, W. S. Sep 2024

Dr Shufeldt's Bibliography, W. S.

The Auk

No abstract provided.


Additions To The Avifauna Of The Pribilof Islands, Alaska, Including Four Species New To North America, G. Dallas Hanna Sep 2024

Additions To The Avifauna Of The Pribilof Islands, Alaska, Including Four Species New To North America, G. Dallas Hanna

The Auk

No abstract provided.


Brabourne And Chubb: 'The Birds Of South America', W. S. Sep 2024

Brabourne And Chubb: 'The Birds Of South America', W. S.

The Auk

No abstract provided.


Identification Of A Clade-Specific Hla-C*03:02 Ctl Epitope Gy9 Derived From The Hiv-1 P17 Matrix Protein, Samuel Kyobe, Savannah Mwesigwa, Gyaviira Nkurunungi, Gaone Retshabile, Moses Egesa, Eric Katagirya, Marion Amujal, Busisiwe C Mlotshwa, Lesedi Williams, Hakim Sendagire, On Behalf Of The Cafgen Consortium, Dithan Kiragga, Graeme Mardon, Mogomotsi Matshaba, Neil A Hanchard, Jacqueline Kyosiimire-Lugemwa, David Robinson Sep 2024

Identification Of A Clade-Specific Hla-C*03:02 Ctl Epitope Gy9 Derived From The Hiv-1 P17 Matrix Protein, Samuel Kyobe, Savannah Mwesigwa, Gyaviira Nkurunungi, Gaone Retshabile, Moses Egesa, Eric Katagirya, Marion Amujal, Busisiwe C Mlotshwa, Lesedi Williams, Hakim Sendagire, On Behalf Of The Cafgen Consortium, Dithan Kiragga, Graeme Mardon, Mogomotsi Matshaba, Neil A Hanchard, Jacqueline Kyosiimire-Lugemwa, David Robinson

Faculty, Staff and Students Publications

Efforts towards an effective HIV-1 vaccine have remained mainly unsuccessful. There is increasing evidence for a potential role of HLA-C-restricted CD8+ T cell responses in HIV-1 control, including our recent report of HLA-C*03:02 among African children. However, there are no documented optimal HIV-1 CD8+ T cell epitopes restricted by HLA-C*03:02; additionally, the structural influence of HLA-C*03:02 on epitope binding is undetermined. Immunoinformatics approaches provide a fast and inexpensive method to discover HLA-restricted epitopes. Here, we employed immunopeptidomics to identify HLA-C*03:02 CD8+ T cell epitopes. We identified a clade-specific Gag-derived GY9 (GTEELRSLY) HIV-1 p17 matrix epitope potentially restricted to HLA-C*03:02. Residues …


Embodiment, Plasticity, And The Re/Production Of Gender, Sex, And Race In Human Biology, Meredith Wilson Sep 2024

Embodiment, Plasticity, And The Re/Production Of Gender, Sex, And Race In Human Biology, Meredith Wilson

Human Biology Open Access Pre-Prints

This paper historically situates human biology research by engaging with feminist science and technology scholars to show how a key mechanism of embodiment, plasticity, is used to re/produce sex and gender binaries in anthropological research and beyond. I begin by defining embodiment and demonstrating its reliance on plasticity. Next, I discuss plasticity and review how and why it has been taken up in human biology research. After, I engage with the works of feminist, trans, and queer scholars who have examined the connection between embodiment, plasticity, and the creation of Western binarized sex and gender. Further, I present how the …


A Revision Of Hong Kong Harvestmen : Biodiversity, Ecological Preferences And Geographical Distribution, Kai Teck Desmond Tan Sep 2024

A Revision Of Hong Kong Harvestmen : Biodiversity, Ecological Preferences And Geographical Distribution, Kai Teck Desmond Tan

Lingnan Theses (MPhil & PhD)

Opiliones, or harvestmen, is a common animal found throughout the world, there are currently over 6,650 species worldwide but the actual number is estimated to exceed 10,000, making it the third largest order in the class Arachnida. Despite its diversity, it is a rather understudied group. In Hong Kong, there are four described species, but the most recent relevant literature dates back to the at least the early 20th century. This thesis focuses on two common species found in Hong Kong: one previously described species (Heterobiantes geniculatus) and one new species (Pseudoleiobunum lutulentum sp. nov.). I …


Early Preclinical Studies Of Ergosterol Peroxide And Biological Evaluation Of Its Derivatives, Taotao Ling, Luz V. Arroyo-Cruz, William R. Smither, Emily K. Seighman, Michelle M. Martínez-Montemayor, Fatima Rivas Sep 2024

Early Preclinical Studies Of Ergosterol Peroxide And Biological Evaluation Of Its Derivatives, Taotao Ling, Luz V. Arroyo-Cruz, William R. Smither, Emily K. Seighman, Michelle M. Martínez-Montemayor, Fatima Rivas

Faculty Publications

Ganoderma lucidum is a medicinal mushroom that produces various pharmacological compounds, including triterpenoids. A major bioactive component of G. lucidum is ergosterol peroxide (EP), which is attributed to its anticancer effects. The current study focuses on the in vitro ADME (absorption, distribution, metabolism, and elimination), in vivo efficacy and toxicity of EP, and the synthesis of new EP derivatives to improve aqueous solubility. It was found that EP is metabolically stable in liver microsomes and plasma. In vivo studies showed that EP inhibits tumor growth in murine cancer models, and it is well tolerated by mice. The maximum tolerated dose …


Quantifying Temperature Effects On Plant Development Rates And Quality Of Compact Container-Grown Pepper, Ryan W. Dickson, Sonali Padhye, Leala M. Machesney, Josh Tebow Sep 2024

Quantifying Temperature Effects On Plant Development Rates And Quality Of Compact Container-Grown Pepper, Ryan W. Dickson, Sonali Padhye, Leala M. Machesney, Josh Tebow

Horticulture Faculty Publications and Presentations

The mean daily temperature effects on plant development rates and quality of compact container-grown pepper were evaluated. Compact pepper cultivars Fresh Bites Yellow and Hot Burrito were grown in greenhouses at 18 to 26 °C (Expt. 1) and 20 to 30 °C (Expt. 2) under supplemental high-pressure sodium lighting and a 16-hour photoperiod. The number of days to first open flower, to first ripe fruit, and from flower to ripe fruit were measured and the development rates calculated by taking the reciprocal (e.g., 1/day). Temperature effects were predicted by fitting a nonlinear exponential function that included the base temperature ( …


A Novel Antigen Biomarker For Detection Of High-Level Of Loa Loa Microfilaremia, Sarah E Greene, Yuefang Huang, Kerstin Fischer, Bruce A. Rosa, John Martin, Makedonka Mitreva, Devyn Yates, Samuel Wanji, Joseph Kamgno, Philip J. Budge, Gary J. Weil, Peter U. Fischer Sep 2024

A Novel Antigen Biomarker For Detection Of High-Level Of Loa Loa Microfilaremia, Sarah E Greene, Yuefang Huang, Kerstin Fischer, Bruce A. Rosa, John Martin, Makedonka Mitreva, Devyn Yates, Samuel Wanji, Joseph Kamgno, Philip J. Budge, Gary J. Weil, Peter U. Fischer

2020-Current year OA Pubs

BACKGROUND: Loiasis is a disease caused by the nematode Loa loa. Serious adverse events sometimes occur in people with heavy L. loa microfilaremia after ivermectin treatment. In regions of Central Africa where loiasis is endemic, this significantly impedes global elimination programs for lymphatic filariasis and onchocerciasis that use mass distribution of ivermectin. Improved diagnostic tests to identify individuals at increased risk of serious adverse events could facilitate efforts to eliminate lymphatic filariasis and onchocerciasis in this region.

METHODS AND FINDINGS: We previously identified the L. loa protein Ll-Bhp-1 in loiasis patient sera. Here, we further characterize Ll-Bhp-1 and report development …


Perspectives On The Clinical Use Of Anti-Amyloid Therapy For The Treatment Of Alzheimer's Disease: Insights From The Fields Of Cancer, Rheumatology, And Neurology, Gregory Jicha, Erin Abner, Elif Pinar Coskun, Mark Huffmyer, Thomas Tucker, Peter T. Nelson Sep 2024

Perspectives On The Clinical Use Of Anti-Amyloid Therapy For The Treatment Of Alzheimer's Disease: Insights From The Fields Of Cancer, Rheumatology, And Neurology, Gregory Jicha, Erin Abner, Elif Pinar Coskun, Mark Huffmyer, Thomas Tucker, Peter T. Nelson

Neurology Faculty Publications

Introduction: The advent of disease-modifying therapies for Alzheimer’s disease (AD) has raised many questions and debates in the field as to the clinical benefits, risks, and costs of such therapies. The controversies have resulted in the perception that many clinicians are apprehensive about prescribing these medications to their patient populations. There also remains widespread uncertainty as to the economic impact, cost benefit ratio, and safety oversight for use of these medications in standard clinical care settings.

Methods: To contextualize such issues, the present study compared anti-amyloid biologic therapy (lecanemab) to four commonly used biologic agents in other fields, including trastuzumab …


Analysis Of The Thermal Aging Kinetics Of Tallow, Chicken Oil, Lard, And Sheep Oil, Yun-Chuan Hsieh, Hao Ouyang, Yulin Zhang, Donyau Chiang, Fuqian Yang, Hsin-Lung Chen, Sanboh Lee Sep 2024

Analysis Of The Thermal Aging Kinetics Of Tallow, Chicken Oil, Lard, And Sheep Oil, Yun-Chuan Hsieh, Hao Ouyang, Yulin Zhang, Donyau Chiang, Fuqian Yang, Hsin-Lung Chen, Sanboh Lee

Chemical and Materials Engineering Faculty Publications

Understanding the thermal aging kinetics of animal oils is of vital importance in the storage and applications of animal oils. In this work, we use four different techniques, including UV-Vis spectrometry, viscometry, impedance spectroscopy, and acid–base titration, to study the thermal aging kinetics of tallow, chicken oil, lard, and sheep oil in the temperature range from 120 ◦C to 180 ◦C. The evolutions of the UV-Vis absorbance, dynamic viscosity, electric impedance, and acid titration are discussed with the defect kinetics. The evolutions of the color centers, defects for dynamic viscosity, and electric dipoles follow second-order, first-order, and zero-order kinetics, respectively. …


Biological Studies Of The Activity Of Manuka Honey Against Carbapenem-Resistant Enterobacterales (Cre) Bacteria, Mamdouh A. Bukhari, Razaz A. Qamash, Rasha A. Bulkhi, Jehad A. Bifari, Omar S. Bakhsh, Khalid O. Hawsawi, Ehab Y. Matuure, Kamil A. Sulaimani, Ashwaq T. Hakim, Maher S. Mujahid Sep 2024

Biological Studies Of The Activity Of Manuka Honey Against Carbapenem-Resistant Enterobacterales (Cre) Bacteria, Mamdouh A. Bukhari, Razaz A. Qamash, Rasha A. Bulkhi, Jehad A. Bifari, Omar S. Bakhsh, Khalid O. Hawsawi, Ehab Y. Matuure, Kamil A. Sulaimani, Ashwaq T. Hakim, Maher S. Mujahid

Saudi Medical Journal

Objectives: To evaluate the potency of Manuka honey UMF +15 against Carbapenem-resistant Enterobacterales (CRE). Bacterial resistance is a worldwide problem that is increasing year by year, especially Carbapenem resistance. Alternatives to antibiotics are needed to both reduce costs, and to reduce the spread of antibiotic resistance, with the ultimate goal of saving lives. Methods: The efficacy of Manuka honey UMF +15 was tested by 2 methods; Well diffusion assay and minimum bactericidal concentration (MBC) against twenty Carbapenem-resistant isolates which collected from Makkah city hospitals during three months of study from 1st of September 2023 up to 1st of December 2023. …


Hhp 529.01: Advanced Physiology Of Exercise I, Charles L. Dumke Sep 2024

Hhp 529.01: Advanced Physiology Of Exercise I, Charles L. Dumke

University of Montana Course Syllabi, 2021-2025

No abstract provided.


Study Of Life History Traits Of Culex Pipiens Linnaeus, 1758 (Diptera: Culicidae) In Laboratory In Erbil Province In Kurdistan Region-Iraq, Dlpak Birkhader Yaba, Shamall Abdulla Al-Muffti Sep 2024

Study Of Life History Traits Of Culex Pipiens Linnaeus, 1758 (Diptera: Culicidae) In Laboratory In Erbil Province In Kurdistan Region-Iraq, Dlpak Birkhader Yaba, Shamall Abdulla Al-Muffti

Polytechnic Journal

This study aimed to study some biological aspects of different stages of Culex pipiens Linnaeus, 1758 in a laboratory that gathered randomly from four regions in Iraq's Kurdistan from Erbil. The results of the current study revealed that the eggs were laid in rafts, and the egg was elongated in shape, which was narrowed in one end. The mean number of laid eggs was 187.4 eggs; the mean hatching percentage was 83.07%, and the mean incubation period was 28.3 hours. The mean length of the first, second, third, and fourth larval instar was 2.21, 3.27,4.72, and 5.73 mm, respectively. The …


Deciphering Cellular And Molecular Mechanism Of Muc13 Mucin Involved In Cancer Cell Plasticity And Drug Resistance, Shabnam Malik, Mohammed Sikander, Mohd Wahid, Anupam Dhasmana, Maryam Sarwat, Sheema Khan, Everardo Cobos, Murali Yallapu, Meena Jaggi, Subhash Chauhan Sep 2024

Deciphering Cellular And Molecular Mechanism Of Muc13 Mucin Involved In Cancer Cell Plasticity And Drug Resistance, Shabnam Malik, Mohammed Sikander, Mohd Wahid, Anupam Dhasmana, Maryam Sarwat, Sheema Khan, Everardo Cobos, Murali Yallapu, Meena Jaggi, Subhash Chauhan

School of Medicine Publications

There has been a surge of interest in recent years in understanding the intricate mechanisms underlying cancer progression and treatment resistance. One molecule that has recently emerged in these mechanisms is MUC13 mucin, a transmembrane glycoprotein. Researchers have begun to unravel the molecular complexity of MUC13 and its impact on cancer biology. Studies have shown that MUC13 overexpression can disrupt normal cellular polarity, leading to the acquisition of malignant traits. Furthermore, MUC13 has been associated with increased cancer plasticity, allowing cells to undergo epithelial-mesenchymal transition (EMT) and metastasize. Notably, MUC13 has also been implicated in the development of chemoresistance, rendering …


Mindfulness And Its Relationship To Emotional Intelligence Of Lifeguards In Jordan, Raghad N. Allaham, Mohammad F. Al-Dababseh Aug 2024

Mindfulness And Its Relationship To Emotional Intelligence Of Lifeguards In Jordan, Raghad N. Allaham, Mohammad F. Al-Dababseh

An-Najah University Journal for Research - B (Humanities)

This study was designed to identify the relationship between Mindfulness and Emotional Intelligence of lifeguards in the Hashemite Kingdom of Jordan Depending on changes in sex, years of experience and the level of the rescue license. Thus, the researchers used the descriptive approach. The study sample consisted of (312) licensed lifeguards working in the swimming pools with (165) men and) 147 (women, and they were randomly selected. The study tool was a questionnaire that was constructed to suit the nature of the current study. The most prominent results showed that there is a relationship between mindfulness and emotional intelligence of …


Loss Of Symmetric Cell Division Of Apical Neural Progenitors Drives Dennd5a-Related Developmental And Epileptic Encephalopathy, Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem Al-Khater, Fowzan S Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine S-Y Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R Lupski, Elysa J Marco, Kirsty Mcwalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, Maha S Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan-Or, Massimo Avoli, Cesar Alves, Gaurav K Varshney, Reza Maroofian, David A Rudko, Peter S Mcpherson Aug 2024

Loss Of Symmetric Cell Division Of Apical Neural Progenitors Drives Dennd5a-Related Developmental And Epileptic Encephalopathy, Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem Al-Khater, Fowzan S Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine S-Y Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R Lupski, Elysa J Marco, Kirsty Mcwalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, Maha S Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan-Or, Massimo Avoli, Cesar Alves, Gaurav K Varshney, Reza Maroofian, David A Rudko, Peter S Mcpherson

Faculty, Staff and Student Publications

Developmental and epileptic encephalopathies (DEEs) feature altered brain development, developmental delay and seizures, with seizures exacerbating developmental delay. Here we identify a cohort with biallelic variants in DENND5A, encoding a membrane trafficking protein, and develop animal models with phenotypes like the human syndrome. We demonstrate that DENND5A interacts with Pals1/MUPP1, components of the Crumbs apical polarity complex required for symmetrical division of neural progenitor cells. Human induced pluripotent stem cells lacking DENND5A fail to undergo symmetric cell division with an inherent propensity to differentiate into neurons. These phenotypes result from misalignment of the mitotic spindle in apical neural progenitors. Cells …


New Imidazolidindionedioximes And Their Pt(Ii) Complexes: Synthesis And Investigation Of Their Antitumoral Activities On Breast Cancer Cells, Emrah Karahan, Tuğba Gençoğlu Katmerli̇kaya, Emel Önal, Aydan Dağ, Ayşe Gül Gürek, Vefa Ahsen Aug 2024

New Imidazolidindionedioximes And Their Pt(Ii) Complexes: Synthesis And Investigation Of Their Antitumoral Activities On Breast Cancer Cells, Emrah Karahan, Tuğba Gençoğlu Katmerli̇kaya, Emel Önal, Aydan Dağ, Ayşe Gül Gürek, Vefa Ahsen

Turkish Journal of Chemistry

Breast cancer is one of the most common types of cancer worldwide and has the most lethality ratio for females among all cancers. Although current cancer therapeutics have made considerable advancements, there is still room for improvement in terms of efficacy. Many anticancer drugs have a risk of causing serious adverse effects due to their non-specific cytotoxic effects on both tumor and healthy cells. New therapeutics might have a greater ability to kill cancer cells, reduce the volume of tumors, and improve overall therapy response rates. Herein, we report the efficient synthesis and characterization of three amphi vic-dioximes and their …


Synthesis And Characterization Of New Hexahydroquinoline Derivatives, Evaluation Of Their Cytotoxicity, Intracellular Ros Production And Inhibitory Effects On Inflammatory Mediators, Ezgi̇ Pehli̇vanlar, Deni̇z Arca Çakir, Sonia Sanajou, Hülya Tezel Yalçin, Terken Baydar, Pinar Erkekoğlu, Hani̇fe Avci, Rahi̇me Şi̇mşek Aug 2024

Synthesis And Characterization Of New Hexahydroquinoline Derivatives, Evaluation Of Their Cytotoxicity, Intracellular Ros Production And Inhibitory Effects On Inflammatory Mediators, Ezgi̇ Pehli̇vanlar, Deni̇z Arca Çakir, Sonia Sanajou, Hülya Tezel Yalçin, Terken Baydar, Pinar Erkekoğlu, Hani̇fe Avci, Rahi̇me Şi̇mşek

Turkish Journal of Chemistry

Inflammation is a response to injury and infection in the organism. It can be categorized as acute and chronic inflammation. Chronic inflammation is the underlying cause of many diseases such as Alzheimer's, diabetes, rheumatoid arthritis, atherosclerosis and cardiovascular diseases. Recent studies have proven the anti-inflammatory properties of 1,4-dihydropyridines (1,4-DHPs) and its derivatives, which have many biological properties including calcium channel blockers. The structures of the synthesized compounds were elucidated by IR, 1H-NMR, 13C-NMR and HRMS methods. The cytotoxic properties of the compounds were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method in 3T3 cell line. Among the 15 compounds, the three compounds …


In-House Polydimethylsiloxane Microfluidic Device On Single Cell Trapping And Culturing Of Leukemia Cell Line: Comparison Between Conventional And Conventional With Centrifugal Methods, Alongkorn Pimpin, Sudchaya Bhanpattanakul, Tepparit Wongpakham, Chomkwan Tawatcharaporn, Thanawit Siha-Umphai, Mookdapa Sinsiriphan, Atikan Chalermchuang, Tewan Tongmanee, Attawut Thanomsridetchai, Thammawit Suwannaphan, Witsaroot Sripumkhaie, Pattaraluck Pattamang, Mayuree Chanasakulniyom, Praprudee Piyaviriyakul, Wutthinun Jeamsaksiri, Achariya Sailasuta, Theerawat Tharasanit, Theerayuth Kaewamatawong Aug 2024

In-House Polydimethylsiloxane Microfluidic Device On Single Cell Trapping And Culturing Of Leukemia Cell Line: Comparison Between Conventional And Conventional With Centrifugal Methods, Alongkorn Pimpin, Sudchaya Bhanpattanakul, Tepparit Wongpakham, Chomkwan Tawatcharaporn, Thanawit Siha-Umphai, Mookdapa Sinsiriphan, Atikan Chalermchuang, Tewan Tongmanee, Attawut Thanomsridetchai, Thammawit Suwannaphan, Witsaroot Sripumkhaie, Pattaraluck Pattamang, Mayuree Chanasakulniyom, Praprudee Piyaviriyakul, Wutthinun Jeamsaksiri, Achariya Sailasuta, Theerawat Tharasanit, Theerayuth Kaewamatawong

The Thai Journal of Veterinary Medicine

To develop a suitable model to study biological and characterization of Cancer stem cells (CSCs), single cell trapping and culturing using microfluidic techniques have become a high-through put system that can manage and control microenvironment and practical intracellular analysis. The aim of this study was to develop and validate a microfluidic device for single cell trapping and culturing using the leukemia cell line as a cell model. Comparison between conventional and conventional with centrifugal methods was also analyzed. To compare trapping efficacy between these 2 methods, leukemia cell concentration of 1.5×106 cells/ml was loaded with a flow rate of 0.25 …


Synthesis Of Addressable Libraries: New Lessons And The Need For Proper Characterization For Microelectrode Array-Based Reactions, Albert Huang Aug 2024

Synthesis Of Addressable Libraries: New Lessons And The Need For Proper Characterization For Microelectrode Array-Based Reactions, Albert Huang

Arts & Sciences Graduate Student Theses and Dissertations

The Moeller group has been developing synthetic tools for building molecular libraries on microelectrode arrays since 2004. Such a library is intriguing because one can take advantage of the library for biological signaling studies. Microelectrode arrays can serve as a powerful platform for those experiments since every electrode in the array can be addressed individually. Unique members of the library targeting biological receptors that one is interested in can be restricted only above unique electrodes in an array. Thus, high-affinity ligands for those receptors can be identified with this strategy. To make this method work, one has to make sure …


Using Phylogenomics And Environmental Metabarcoding To Understand The Distribution And Evolutionary Histories Of Amoebae, Robert E. Jones Aug 2024

Using Phylogenomics And Environmental Metabarcoding To Understand The Distribution And Evolutionary Histories Of Amoebae, Robert E. Jones

Theses and Dissertations

Protists are defined as eukaryotic organisms that are not animals, land plants, or fungi and make up the vast majority of eukaryotic diversity. Unfortunately, they are often overlooked and under sampled. Some rationales behind this are that they are often microscopic, most rarely the cause of human disease, and are often difficult to get into culture. Molecular phylogenetics has revolutionized our understanding of the evolutionary history of eukaryotes and without a clear picture of protist evolution our understanding would be severely hindered. Phylofisher is an easy-to-use phylogenomic software package, with an accompanying database and various utilities, intended for deep phylogenomic …


Introducing Isomad, A Compilation Of Isotopic Datasets For Madagascar, Sean W. Hixon, Ricardo Fernandes, Antonin Andriamahaihavana, Andrea L. Baden, Marina B. Blanco, Guillaume Caulier, Melanie Dammhahn, Igor Eeckhaut, Timothy M. Eppley, Natalie Vasey, Multiple Additional Authors Aug 2024

Introducing Isomad, A Compilation Of Isotopic Datasets For Madagascar, Sean W. Hixon, Ricardo Fernandes, Antonin Andriamahaihavana, Andrea L. Baden, Marina B. Blanco, Guillaume Caulier, Melanie Dammhahn, Igor Eeckhaut, Timothy M. Eppley, Natalie Vasey, Multiple Additional Authors

Anthropology Faculty Publications and Presentations

Abstract We present the first open-access, island-wide isotopic database (IsoMad) for modern biologically relevant materials collected on Madagascar within the past 150 years from both terrestrial and nearshore marine environments. Isotopic research on the island has increasingly helped with biological studies of endemic organisms, including evaluating foraging niches and investigating factors that affect the spatial distribution and abundance of species. The IsoMad database should facilitate future work by making it easy for researchers to access existing data (even for those who are relatively unfamiliar with the literature) and identify both research gaps and opportunities for using various isotope systems to …