Digital Commons Network^™

Spatial Dialogues Between Exhibited Interiors And Cultural Exteriors: How Local Museums Connect To The Community, Nuttinee Karnchanaporn, Chanida Lumthaweepaisal

Interiority

Local museums can no longer simply wait for visitors to come and see their exhibited interiors. They are tasked with community engagement and cultural continuity. They must remain relevant to their communities, but how? Recently, local museums, especially those promoting local history, have struggled to relate to rapidly changing and diverse communities. To ensure museums are community-centred spaces, this research suggests that their spatial components need rethinking. While exhibitions in local museums should be designed through a collaboration and co-creation process between museum staff and locals, semi-outdoor and exterior spaces could be organised to host community gatherings, cultural events, and …

Interiority In Sade Village Indigenous Corridor, Astrid Kusumowidagdo, Melania Rahadiyanti, Tri Noviyanto Puji Utomo

Interiority

This study aims to find and define interiority as an initiative to preserve culture and traditions in Sade Village, Lombok Island, a tourist area in Indonesia. This study adopted qualitative research with the case study method, recording several data sources through field observation, literature studies, archives, and in-depth interviews with community leaders. This study identifies the typology of areas that create psychological, form-based, atmospheric, and programmatic interiority (Teston, 2020) in various configurations. This study found the types of interiorities in Sade Village that contribute to the corridor’s uniqueness, visitors’ feeling of insideness, and the area’s maintenance. Five categories of interiority, …

Work From Home: Lessons Learned And Implications For Post-Pandemic Workspaces, Beth L. Mcgee, Ryan J. Couillou, Kristjan Maalt

Interiority

The experience of working from home (WFH) has evolved due to the COVID-19 response. A concurrent mixed-methods approach was used to assess the experiences and needs of WFH during COVID-19 pandemic across eight countries. Input concerning office workspace modifications was also explored. Participants (n = 82) were from Asia, Europe, and North America. Participants were working from home more and indicated they were somewhat satisfied with WFH and saw no change in productivity. The most common experience was feeling distracted while others experienced focus or calmness. Most participants were challenged by the lack of appropriate furniture and equipment, as …

Loss-Of-Function KCa2.2 Mutations Abolish Channel Activity, Young-Woo Nam, Mohammad Asikur Rahman, Grace Yang, Razan Orfali, Meng Cui, Miao Zhang

Pharmacy Faculty Articles and Research

Small-conductance Ca²⁺-activated potassium channels subtype 2 (K_Ca2.2, also called SK2) are operated exclusively by a Ca²⁺-calmodulin gating mechanism. Heterozygous genetic mutations of K_Ca2.2 channels have been associated with autosomal dominant neurodevelopmental disorders including cerebellar ataxia and tremor in humans and rodents. Taking advantage of these pathogenic mutations, we performed structure-function studies of the rat K_Ca2.2 channel. No measurable current was detected from HEK293 cells heterologously expressing these pathogenic K_Ca2.2 mutants. When co-expressed with the K_Ca2.2_WT channel, mutations of the pore-lining amino acid residues (I360M, Y362C, G363S …

Development Of Application For Early Intervention Speech Therapy In Children With Intellectual Disability, Fairus Niratama, Wagino Wagino, Wiwik Widajati, Sri Joeda Andajani

Journal of ICSAR

This study aims to describe the stages of the speech therapy application development process. This research produces an android application product that can be used in early intervention in speech therapy for children with intellectual disabilities. This development research is based on the development method of Gall, et al. (2007), and only carried out up to five stages, namely: 1) Research and information collecting (searching and collecting data), 2) Planning, 3) Develop preliminary form of product, 4) Preliminary field testing, 5) Main product revision. The data collection method in the form of a Likert scale was used in this study. …

Instrument To Assess The Perception Of Sound And Rhythm For Children With Hearing Impairment, Tati Hernawati, Endang Rusyani, Setyo Wahju Wibowo, Nenden Ineu Herawati

Journal of ICSAR

Children with hearing impairments experience hearing loss from mild to profound, which is grouped into hard of hearing and deafness. The direct impact of hearing loss is the inability/difficulty to catch various sounds, including the sound of the language. Those with hearing impairments must be made aware of sound, especially children classified as hard of hearing, whose remaining hearing must be stimulated to train their sensitivity so that their hearing function can be optimized. Therefore, they are given special services in the form Development of Communication, Perception of Sound and Rhythm. The program provided must be under their learning conditions …

Nanoscale Hafnium Metal-Organic Frameworks Enhance Radiotherapeutic Effects By Upregulation Of Type I Interferon And Tlr7 Expression, Eunseo Choi, Madeleine R. Landry, Nathan Pennock, Katherine Weinfurter, Multiple Additional Authors

Chemistry Faculty Publications and Presentations

Recent preclinical and clinical studies have highlighted the improved outcomes of combination radiotherapy and immunotherapy. Concurrently, the development of high-Z metallic nanoparticles as radiation dose enhancers has been explored to widen the therapeutic window of radiotherapy and potentially enhance immune activation. In this study, we evaluate folate-modified hafnium-based metal-organic frameworks (HfMOF-PEG-FA) in combination with imiquimod, a TLR7 agonist, as a well-defined interferon regulatory factor (IRF) stimulator for local antitumor immunotherapy. The enhancement of radiation dose deposition by HfMOF-PEG-FA and subsequent generation of reactive oxygen species (ROS) deregulates cell proliferation and increases apoptosis. HfMOF-PEG-FA loaded with imiquimod (HfMOF-PEG-FA@IMQ) increases DNA double-strand …

Extracellular Matrix (Ecm) And Fibrosis In Adipose Tissue: Overview And Perspectives, Kai Sun, Xin Li, Philipp E Scherer

Faculty, Staff and Student Publications

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition. In obese adipose-depots, hypoxia stimulates multiple pro-fibrotic signaling pathways in different cell populations, thereby inducing the overproduction of the ECM components, including collagens, noncollagenous proteins, and additional enzymatic components of ECM synthesis. As a consequence, local fibrosis develops. The result of fibrosis-induced mechanical stress not only triggers cell necrosis and inflammation locally in adipose tissue but also leads to system-wide lipotoxicity and insulin resistance. A better understanding …

"The Producers" Of Tax Abuse: The Corrupting Effects Of Tax Laws And Tax Reliefs In The U.K. Film Industry, Lorenzo Pasculli, Stuart Maclennan

Law and Contemporary Problems

No abstract provided.

The Role Of Information And Communication Technology (Ict)) Towards Providing Effective Library Services In Special Libraries Of Adamawa Broadcasting Corporation Yola, Adamawa State Nigeria, Babangida Umar Babayi Dr., John Thlama Ijabula, Juliet Olouchi Peter, Basaka Abubakar Aminu Dr.

Library Philosophy and Practice (e-journal)

The study examined the role of information and communication technology (ICT)) towards providing effective library services in special libraries of Adamawa broadcasting corporation Yola, Adamawa State Nigeria. The study employed four objectives of the study and four research questions. The study adopted the descriptive survey research method. Questionnaire was used as instrument for data collection. The population of the study consists of fifteen (15) staff. This study adopted purposive sampling technique where. Descriptive statistic was used as the method of data analysis. The study revealed that there is availability of ICTs such as: CDs, hard drives, flash and also photocopier …

A Non-Reference Evaluation Of Underwater Image Enhancement Methods Using A New Underwater Image Dataset, Ashraf Saleem, Sidike Paheding, Nathir Rawashdeh, Ali Awad, Navjot Kaur

Michigan Tech Publications, Part 1

The rise of vision-based environmental, marine, and oceanic exploration research highlights the need for supporting underwater image enhancement techniques to help mitigate water effects on images such as blurriness, low color contrast, and poor quality. This paper presents an evaluation of common underwater image enhancement techniques using a new underwater image dataset. The collected dataset is comprised of 100 images of aquatic plants taken at a shallow depth of up to three meters from three different locations in the Great Lake Superior, USA, via a Remotely Operated Vehicle (ROV) equipped with a high-definition RGB camera. In particular, we use our …

Rethinking The Idea Of Indigeneity: An Indigenous Liberationist Response To Hindutva Cooptation And Assimilationist Agenda In Northeast India, R. C. Jongte

Journal of Hindu-Christian Studies

No abstract provided.

Book Review: Religion, Secularism, And Ethnicity In Contemporary Nepal. Edited By David Gellner, Sondra Hausner, And Chiara Letizia., Joseph Evans

Journal of Hindu-Christian Studies

No abstract provided.

Myelin Lipid Metabolism And Its Role In Myelination And Myelin Maintenance, Joseph A Barnes-Vélez, Fatma Betul Aksoy Yasar, Jian Hu

Faculty, Staff and Student Publications

Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high abundance of membrane lipids is one of myelin's salient features that contribute to its unique role as an insulator that electrically isolates nerve fibers across their myelinated surface. The most abundant lipids in myelin include cholesterol, glycosphingolipids, and plasmalogens, each playing critical roles in myelin development as well as function. This review serves to summarize the role of lipid metabolism in myelination and myelin maintenance, as well as the molecular determinants of myelin lipid homeostasis, with an emphasis on findings from genetic models. In addition, the implications …

Lanthorn, Vol. 57, No. 20, January 30, 2023, Grand Valley State University

Volume 57, August 1, 2022 - April 10, 2023

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Development Of Visual Perception Assessment In The Form Of An Interactive Digital Book For Students With Mental Disabilities, Neny Yuniarti, Ahsan Romadlon Junaidi, Asep Sunandar

Journal of ICSAR

Children with special needs will achieve good learning outcomes if educators conduct assessments. Assessment is a process to collect information about abilities, advantages and needs that will be used as considerations and decisions related to the preparation of academic programs. This study aims to develop a visual perception assessment product in the form of a digital book for students with intellectual disability which is expected to be able to measure the ability, difficulty and needs in aspects of the development of children's visual perception with cases of mental impairment needed as consideration in planning learning programs, especially in reading learning. …

Development Of Sign Language Application Pesan Kuliah With Material Substance Modification Based On Student Characteristics With Hearing Impaired, Utomo Utomo, Dewi Ratih Rapisa, Eviani Damastuti, Dewi Juwita Susanti

Journal of ICSAR

Lack of mastery of receptive and expressive language in students with hearing impairments affects the ability to compose scientific papers. Assistive technology for writing scientific papers can support students with hearing impairments in completing scientific paper assignments at various semester levels. This research aims to develop assistive technology that can make it easier for students with hearing impairments to participate in learning in tertiary institutions to create accessible learning for students with hearing impairments. Sign language application “PESAN KULIAH” (Guidelines for Writing Scientific Papers) is made by adjusting the characteristics of hearing impairments to make it easier to understand how …

The Interactive Web-Based Learning In Online Learning For Blind Students And Deaf Students In Higher Education, Eka Yuli Astuti, Teti Ratnawulan, Yoga Budhi Santoso, Dwi Endah Pertiwi, Prinanda Gustarina Ridwan, Zulfa Rahmah Effendi

Journal of ICSAR

Online learning has been running in Indonesian universities due to the COVID-19 outbreak. Online learning has become a challenge to both parties, lecturers, and students with special needs. The use of several online platforms for learning has not provided accessibility for students who are blind and deaf. To pursue friendly learning in inclusive classrooms for blind and deaf students, then we need a facility that supports learning for blind and deaf students. The purpose of the study is to develop a learning model that can be used for online learning using an interactive website. The interactive Web-Based Learning Model is …

Dwarf Bunt In Winter Wheat, Justin Clawson, Claudia Nischwitz, Margaret Krause, Will Krause

All Current Publications

Dwarf bunt or stinking smut is a disease that impacted Utah winter wheat production in the 1930s, resulting in fields with 95% infections. Breeding and selection of resistant varieties has irradiated the disease. As organic production of winter wheat increases, selecting resistant varieties will become of utmost importance to prevent crop loss.

Exploration Of The Nuclear Proteomes In The Ciliate Oxytricha Trifallax, Michael W Lu, Leslie Y Beh, V Talya Yerlici, Wenwen Fang, Katarzyna Kulej, Benjamin A Garcia, Laura F Landweber

2020-Current year OA Pubs

Nuclear dimorphism is a fundamental feature of ciliated protozoa, which have separate somatic and germline genomes in two distinct organelles within a single cell. The transcriptionally active somatic genome, contained within the physically larger macronucleus, is both structurally and functionally different from the silent germline genome housed in the smaller micronucleus. This difference in genome architecture is particularly exaggerated in

Unrecognized Functional Dyspepsia Among Those With Refractory Chronic Constipation: Analysis Of A Tertiary Cohort, Taylor Boyd, Mary Paz, Imama Ahmad, Fatima Rao, Ahmad Samad, Isabelle Garcia-Fischer, Casey Silvernale, Helen Burton Murray, Kyle Staller

Student Papers, Posters & Projects

BACKGROUND AND AIMS: Patients with functional constipation (FC) are frequently dissatisfied with current treatment options which may be related to persistent, unaddressed symptoms. We hypothesized that refractory FC may actually represent functional dyspepsia (FD) overlap. Among adults presenting with refractory FC, we sought to (1) identify the prevalence of concurrent FD and (2) identify the symptoms and presentations most frequently associated with concurrent FD and FC.

METHODS: We assembled a retrospective cohort of 308 patients sequentially presenting to a tertiary neurogastroenterology clinic for evaluation of refractory FC, defined as having failed first-line therapy. Using Rome IV criteria, trained raters identified …

“For The Moment, I Am Not F*Cking,” I Am Tweeting: Platforms Of / As Sexuality, Jacob Johanssen

CLCWeb: Comparative Literature and Culture

This article develops the argument that digital platforms are significantly infused with originary (and unconscious) residues of the sexual. Drawing on Laplancheian conceptualizations of sexuality, I argue that the digital has always been sexual(ised) in itself – a process that precedes and exceeds the erotic or pornographic. For Laplanche, sexuality is constitutive of the human subject as such. Infantile sexuality is shaped and transformed in an enigmatic relation with the caregiver. Drawing on this model as an analogy, I claim that users are drawn to platforms because they (unconsciously) desire to return to infantile sexuality and a holding environment but …

Community Despite Connection: Resisting The Digital Logics Of Optimization And Failure, Irina Kalinka

CLCWeb: Comparative Literature and Culture

If a certain brand of aspirational tech-utopian discourse is to be believed, those privileged enough to be plugged into digital information technology are living through a golden age of connection. Platforms claim to facilitate sharing and partaking, bring people together, and bestow upon them new and improved spaces to gather and build communities. While reality differs decidedly from such idealized conceptions, it is nonetheless crucial to ask what kind of guiding vision is being instituted through such representational efforts: namely, the figure of community made operational and optimizable. This project will reject such idealized visions of coherent communities drawn together …

The Social Sinthome, Ryan Engley

CLCWeb: Comparative Literature and Culture

Much of the critical discourse on social media misidentifies its problematic features as bugs, or problems to solve. Supposed solutions to these problems tend to focus on individual actions. We should delete the apps, own our own data, never click on recommended videos, and realize that we are the product. But if predatory algorithms succeed by individuating people—selling people “choice” and “options” as it harvests user data—then an entire online ecosystem arranged through the logic of that design can neither be meaningfully challenged nor effectively understood at the level of the individual alone. Transformative action addressing social media can only …

Everybody Wants To Be A Fascist Online: Psychoanalysis And The Digital Architecture Of Fascism, Anthony Faramelli, Imogen Piper

CLCWeb: Comparative Literature and Culture

Félix Guattari and Franco Berardi have both argued that media ecologies and psychic ecologies are intimately intertwined and as such, any exploration of the collective unconscious must engage with how the mind is formed with and through media. This understanding of networks of interdependence necessitates an exploration of how platformization has impacted users” collective psyche. Drawing from psychosocial theory, psychoanalysis and the work of Félix Guattari, this article analizes the micropolitics of desire of digital platforms, with an explicit focus on how algorithmic structures amplify extreme Right content, allowing fascisms to metastasis throughout digital spaces. It will first examine the …

“There Is No Pandemic”: On Memes, Algorithms And Other Interpassive Forms Of Right-Wing Disbelief, Scott Krzych

CLCWeb: Comparative Literature and Culture

This essay examines several prominent memes that have circulated on Right-wing social media during the Covid-19 pandemic. The memes coordinate what I describe as a mode of interpassive humor, which positions those who “believe” in the crisis as naïve dupes, infantilizing those subjects who have fallen prey to the idea that they should take the pandemic seriously, and thereby delegating fearfulness to the other so that reactionary Covid-19 denialists may continue with their lives unaffected. The essay thereby seeks to draw suggestive lines of affiliation between studies of digital memes, evolutionary mimetics, and psychoanalytic theory, pointing to the algorithmic …

Lacan And The Algorithm, Clint Burnham

CLCWeb: Comparative Literature and Culture

Exploring the development of algorithms in Lacanian theory, specifically the "R schema" in the 1950s, I argue that psychoanalysis, read through contemporary debates about the "algorithmic cult" of Netflix and other avatars of popular culture, can be said to reveal the inhuman, machinic essence of subjectivity. The etiology of algorithms, mathemes, and other formulae and diagrams in Lacan’s oeuvre has been under-studied, in part because for some readers they are not as attractive as his more bravura flourishes of word play as exegetical excess, and in part because they derive largely from the ‘hard’ structuralist moment of his work in …

When Sexuality Becomes Healing: An Interview With Elsbeth Fraanje On Her Documentary Sexual Healing, Johan Roeland

Journal of Religion & Film

This is an interview with Elsbeth Fraanje, the director of Sexual Healing.

Sexual Healing, Johan Roeland

Journal of Religion & Film

This is a film review of Sexual Healing (2022) directed by Elsbeth Fraanje.

L’Intelligence Artificielle En Tant Que Clinicien : Argument En Faveur D’Un Recours Éthique Aux Technologies Futures Dans Le Milieu Médical, Sara Gaines

The International Journal of Ethical Leadership Special Volumes

No abstract provided.