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The Kenyon Collegian - April 27, 2023

The Kenyon Collegian

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From Pedagogical To The Practical: A Study Linked By Japanese Themes, Kennedy Lomont

Master of Arts in English Plan II Graduate Projects

This portfolio consists of three essays linked by Japanese themes and also includes a practical project. These papers delve into the subjects of Japenese incarceration, magical girl anime, and Noh theater. My practical portion contains the materials that I have created and refined for job search purposes.

Regenerative Medicine For Tendon/Ligament Injuries: De Novo Equine Tendon/Ligament Neotissue Generation And Application, Takashi Taguchi

LSU Doctoral Dissertations

Tendon and ligament injuries are debilitating conditions across species. Poor regenerative capacities of these tissues limit restoration of original functions. The first study evaluated the effect of cellular administration on tendon/ligament injuries in horses using meta-analysis. The cellular administration was effective in restoring ultrasonographic echogenicity and increasing vascularity during early phase of healing. Additionally, it improved microstructural organization of healed tissue in terms of cellularity and fiber alignment. However, the study did not support its use for increasing rate of return to performance, expression/deposition of tendon-specific genes/proteins, or mechanical properties.

The findings led to the second study that engineered implantable …

The Student Movement Volume 107 Issue 23: So Long, Farewell: Students Step Into The Future, Anna Pak, Gloria Oh, Grace No, Solana Campbell, Ysabelle Fernando, Amelia Stefanescu, Brendan Oh, Bella Hamann, Terika Williams, Gabi Francisco, Abraham Bravo, Elizabeth Dovich

The Student Movement v. 107 (2022-2023)

HUMANS

Advice to Younger Selves, Interviewed by: Anna Pak

Finals Stress Management, Gloria Oh

Farewell to Pastor Dwight Nelson, Student Movement Staff

What does AANHPI Heritage Month Mean?, Grace No

ARTS & ENTERTAINMENT

Currently: Reflecting on the Original Script, Solana Campbell

In Memory of K.V. Rathnam, Ysabelle Fernando

"The Deal" Premiers at Sonscreen Film Festival, Solana Campbell

Through Their Eyes: AANHPI Expression, Amelia Stefanescu

NEWS

A Night at AU: SASA Cultural Night, Solana Campbell

Interview with Professor Daniel Weber: Envision Magazine, Interviewed By: Brendan Oh

Interview with Gloria Oh: Transforming an Idea into Reality, Interviewed By: Brendan Oh

IDEAS

All …

Analysis Of Wild Rodent Gut Microbiota As A Function Of Exposure To Ticks And Tick-Borne Pathogens, Joshua Pandian

Honors Theses

Due to advances in high-throughput parallel sequencing, researchers have conducted novel studies exploring relationships between microbiome compositions and different aspects of organism health. Some of these studies have shown that the gut microbiome of rodent models has effects on organism health and behavior and that infection with pathogens and the composition of the skin microbiome are linked to changes in gut microbiome composition. While previous studies have shown how vector microbiota impact vector behavior and pathogen transmission, the effect vectors have on reservoir species microbiomes has been a less prominent focus. We were interested in the relationships between tick parasitism, …

The Biggest Hoax? Investigating The Work-Life Balance Of Veteran Secondary Teachers In North Mississippi Public Schools, Anna Grace Robinson

Honors Theses

This thesis investigates the struggle with work-life balance among veteran secondary teachers in public North Mississippi schools. Primary research questions include a) How do veteran teachers describe the struggle with work-life balance, b) What coping strategies over their career seem helpful?, and c)What changes could be made to the educational system to better support public school teachers in their pursuit of work-life balance? At what level should those changes occur? Qualitative data was collected by interviewing five teachers from middle and high schools in the North Mississippi region and analyzed to understand emergent themes from the interviews. This research found …

Little Trolls, Logan Gagnepain

Celebrating Scholarship and Creativity Day (2018-)

A short story set in a fictional Earth in which trolls, elves, humans, and other species live together in an unsteady harmony. The short story documents the horrific consequences of racism and prejudice within the criminal system, even if the targets of the worst violence aren't human.

“The Queer, Lonely, Intense, Inner Lives Of Their Children”: Psychoanalysis, Mysticism, And Mabel Dodge Luhan’S Narrative Approach To The Story Of Her Childhood, Lauren M. Franken

Department of English: Dissertations, Theses, and Student Research

This thesis explores Mabel Dodge Luhan’s narrative approach to writing Background (1933), the first of her four published volumes of autobiography titled Intimate Memories. In the first section I lay the groundwork for this analysis with a brief examination of Background’s publication history. The succeeding two sections offer a historical framework for understanding late nineteenth and early twentieth-century American conceptualizations of childhood, Freudian psychoanalysis, and mysticism. Considering the various lenses through which Luhan analyzed her childhood memories provides a more complex awareness of her narrative approach. The fourth section engages in a close reading of the sections of …

Ido1 And Inflammatory Neovascularization: Bringing New Blood To Tumor-Promoting Inflammation, Alexander J. Muller, Arpita Mondal, Souvik Dey, George C Prendergast

Kimmel Cancer Center Faculty Papers

In parallel with the genetic and epigenetic changes that accumulate in tumor cells, chronic tumor-promoting inflammation establishes a local microenvironment that fosters the development of malignancy. While knowledge of the specific factors that distinguish tumor-promoting from non-tumor-promoting inflammation remains inchoate, nevertheless, as highlighted in this series on the 'Hallmarks of Cancer', it is clear that tumor-promoting inflammation is essential to neoplasia and metastatic progression making identification of specific factors critical. Studies of immunometabolism and inflamometabolism have revealed a role for the tryptophan catabolizing enzyme IDO1 as a core element in tumor-promoting inflammation. At one level, IDO1 expression promotes immune tolerance …

Adipose Tissue Metabolic Changes In Chronic Kidney Disease, Eurico Serrano, Prashamsa Shenoy, Maria Paula Martinez Cantarin

Division of Nephrology Faculty Papers

Adipose tissue is a complex organ whose functions go beyond being an energy reservoir to sustain proper body energy homeostasis. Functioning as an endocrine organ, the adipose tissue has an active role in the body's metabolic balance regulation through several secreted factors generally termed as adipokines. Thus, adipose tissue dysregulation in chronic kidney disease (CKD) can have a deep impact in the pathophysiology of diseases associated with metabolic dysregulation including metabolic syndrome, insulin resistance (IR), atherosclerosis, and even cachexia. CKD is a progressive disorder linked to increased morbidity and mortality. Despite being characterized by renal function loss, CKD is accompanied …

The Problem Is The Court, Not The Constitution, Jonathan Feingold

Faculty Scholarship

“But first, we must believe.” So concludes The Antiracist Constitution, where Brandon Hasbrouck confronts an uneasy question: In the quest for racial justice, is the Constitution friend or foe? Even the casual observer knows that constitutional law is no friend to racial justice. In the nineteenth century, Plessy v. Ferguson blessed Jim Crow. In the twentieth century, Washington v. Davis insulated practices that reproduce Jim Crow. Now in the twenty-first century, pending affirmative action litigation invites the Supreme Court to outlaw efforts to remedy Jim Crow.

A Graph-Based Approach To Studying The Spread Of Radical Online Sentiment, Le Nguyen

Theses

The spread of radicalization and extremism through the Internet is a growing problem. We are witnessing a rise in online hate groups, inspiring the impressionable and vulnerable population towards extreme actions in the real world. Though the body of research to address these issues is growing in kind, they lack a key understanding of the structure and behavior of online extremist com- munities. In this thesis, we study the structure and behavior of extremist online communities and the spread of hateful sentiments through them to address this gap in the research. We propose a novel Graph-Based Approach to Studying the …

A Call For Planetary Kinship: The Development Of New Forms Of Subjectivity In Jeff Vandermeer's Annihilation, Jennifer Kinne

Masters Theses

This thesis joins a vibrant conversation on the importance of storytelling in an age of climate change through an analysis of Jeff VanderMeer’s Annihilation, a strange and prophetic novel whose environments and characters are confronted with significant ecological devastation and transformation. It explores the ways in which VanderMeer opens liminal spaces between the human and nonhuman through his usage of the New Weird genre, uncanny and abcanny imagery, and monstrous characters.

In my first chapter, I will explore the emerging world of New Weird fiction and argue that this genre is uniquely suited to addressing climate change, namely because of …

What Is The Intention To Move And When Does It Occur?, Antonio I. Triggiani, Gabriel Kreiman, Cara Lewis, Uri Maoz, Alfred Mele, Liad Mudrik, Adina L. Roskies, Aaron Schurger, Mark Hallett

Psychology Faculty Articles and Research

In 1983 Benjamin Libet and colleagues published a paper apparently challenging the view that the conscious intention to move precedes the brain’s preparation for movement. The experiment initiated debates about the nature of intention, the neurophysiology of movement, and philosophical and legal understanding of free will and moral responsibility. Here we review the concept of “conscious intention” and attempts to measure its timing. Scalp electroencephalographic activity prior to movement, the Bereitschaftspotential, clearly begins prior to the reported onset of conscious intent. However, the interpretation of this finding remains controversial. Numerous studies show that the Libet method for determining intent, W …

Resolution Of Cisplatin-Induced Fatigue Does Not Require Endogenous Interleukin-10 In Male Mice, Kiersten Scott, Nabila Boukelmoune, Cullen Taniguchi, A Phillip West, Cobi J Heijnen, Robert Dantzer

Faculty, Staff and Student Publications

Based on previous results showing a pivotal role of endogenous interleukin-10 (IL-10) in the recovery from cisplatin-induced peripheral neuropathy, the present experiments were carried out to determine whether this cytokine plays any role in the recovery from cisplatin-induced fatigue in male mice. Fatigue was measured by decreased voluntary wheel running in mice trained to run in a wheel in response to cisplatin. Mice were treated with a monoclonal neutralizing antibody (IL-10na) administered intranasally during the recovery period to neutralize endogenous IL-10. In the first experiment, mice were treated with cisplatin (2.83 mg/kg/day) for five days and IL-10na (12 μg/day for …

Instaanalytica, Sapna Maduraimuthu

Masters Projects

This project aims to analyze social media trends using Instagram as the primary source of data extraction and provides insights such as understanding engagement rates, top hashtags, optimal posting times, and post rankings based on engagement rates and sentiment scores thus the users can understand their audience and improve their posting strategies. Firstly, the profile trend chart and area chart based on the average engagement rate is generated to obtain day, week, or month engagement rates. Secondly, text preprocessing is done before generating a word cloud displaying the most frequently occurring words in the captions. The size of each word …

Positive Selection Of Somatically Mutated Clones Identifies Adaptive Pathways In Metabolic Liver Disease, Zixi Wang, Shijia Zhu, Yuemeng Jia, Yunguan Wang, Naoto Kubota, Naoto Fujiwara, Ruth Gordillo, Cheryl Lewis, Min Zhu, Tripti Sharma, Lin Li, Qiyu Zeng, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Purva Gopal, Tao Wang, Matt Hoare, Peter Campbell, Yujin Hoshida, Hao Zhu

Faculty, Staff and Student Publications

Somatic mutations in nonmalignant tissues accumulate with age and injury, but whether these mutations are adaptive on the cellular or organismal levels is unclear. To interrogate genes in human metabolic disease, we performed lineage tracing in mice harboring somatic mosaicism subjected to nonalcoholic steatohepatitis (NASH). Proof-of-concept studies with mosaic loss of Mboat7, a membrane lipid acyltransferase, showed that increased steatosis accelerated clonal disappearance. Next, we induced pooled mosaicism in 63 known NASH genes, allowing us to trace mutant clones side by side. This in vivo tracing platform, which we coined MOSAICS, selected for mutations that ameliorate lipotoxicity, including mutant genes …

Resolution Of Cisplatin-Induced Fatigue Does Not Require Endogenous Interleukin-10 In Male Miceb, Kiersten Scott, Nabila Boukelmoune, Cullen Taniguchi, A Phillip West, Cobi J Heijnen, Robert Dantzer

Faculty, Staff and Student Publications

Based on previous results showing a pivotal role of endogenous interleukin-10 (IL-10) in the recovery from cisplatin-induced peripheral neuropathy, the present experiments were carried out to determine whether this cytokine plays any role in the recovery from cisplatin-induced fatigue in male mice. Fatigue was measured by decreased voluntary wheel running in mice trained to run in a wheel in response to cisplatin. Mice were treated with a monoclonal neutralizing antibody (IL-10na) administered intranasally during the recovery period to neutralize endogenous IL-10. In the first experiment, mice were treated with cisplatin (2.83 mg/kg/day) for five days and IL-10na (12 μg/day for …

Human Sapovirus Replication In Human Intestinal Enteroids, Gabriel Euller-Nicolas, Cécile Le Mennec, Julien Schaeffer, Xi-Lei Zeng, Khalil Ettayebi, Robert L Atmar, Françoise S Le Guyader, Mary K Estes, Marion Desdouits

Faculty, Staff and Students Publications

Human sapoviruses (HuSaVs), like human noroviruses (HuNoV), belong to the Caliciviridae family and cause acute gastroenteritis in humans. Since their discovery in 1976, numerous attempts to grow HuSaVs in vitro were unsuccessful until 2020, when these viruses were reported to replicate in a duodenal cancer cell-derived line. Physiological cellular models allowing viral replication are essential to investigate HuSaV biology and replication mechanisms such as genetic susceptibility, restriction factors, and immune responses to infection. In this study, we demonstrate replication of two HuSaV strains in human intestinal enteroids (HIEs) known to support the replication of HuNoV and other human enteric viruses. …

The Melody Of Memory: Exploring The Effect Of Music Therapy On Language And Memory Recall In Adults With Alzheimer’S Disease, Ariel Nicole Furgat

Theses and Dissertations

Background: Music is an important part of life for the lives of many seniors. Priorresearch has indicated that music is beneficial to adults with Alzheimer’s disease. Purpose: With the intent to advocate for music therapists working in memory care, the purpose of this study was to investigate the effect of music therapy intervention on language and memory in people with Alzheimer’s disease. Three research questions were addressed in this study: (1) Of the three conditions (music therapy, recorded music, control), which appear to result the most change in MMSE scores in adults with moderate Alzheimer’s disease? What differences are observed …

Clonal Haematopoiesis And Risk Of Chronic Liver Disease, Waihay J. Wong, Connor Emdin, Alexander G. Bick, Seyedeh M. Zekavat, John Blangero, Joanne E. Curran, Ravi Duggirala, Harald H. H. Goring, Michael Mahaney, Juan M. Peralta

School of Medicine Publications

Chronic liver disease is a major public health burden worldwide1. Although different aetiologies and mechanisms of liver injury exist, progression of chronic liver disease follows a common pathway of liver inflammation, injury and fibrosis2. Here we examined the association between clonal haematopoiesis of indeterminate potential (CHIP) and chronic liver disease in 214,563 individuals from 4 independent cohorts with whole-exome sequencing data (Framingham Heart Study, Atherosclerosis Risk in Communities Study, UK Biobank and Mass General Brigham Biobank). CHIP was associated with an increased risk of prevalent and incident chronic liver disease (odds ratio = 2.01, 95% confidence …

Multimodal Models Of Animal Sex In Scientific Literature: Breaking Binaries Leads To A Better Understanding Of Ecology And Evolution, Isabella Gates, Anisha Pethkar, Marcus Piattoni, Alexis Rossi, Sara E. Lipshutz

Undergraduate Research and Engagement Symposium

‘Sex’ is often used to describe a suite of phenotypic and genotypic traits of an organism related to reproduction. However, not all these traits are necessarily linked, and the rhetorical collapse of variation into a single term elides much of the complexity inherent in reproductive phenotypes. We conducted a meta-analysis of scientific literature to investigate how terminology related sexual phenotypes changes over time. We find that the conflation of gender and sex has increased, and there is a mammalian bias in this conflation. We highlight how a more inclusive and expansive framework for sex can clarify studies of sexual diversity.

Got Milk?, Nicole Papanton, Lucia Macoretta, Drew Evans, Neil Beran

Undergraduate Research and Engagement Symposium

This multidisciplinary study examines the liquid dairy and alternative milk markets through four different lenses, exploring the intersection of consumer sentiment, industry financial performance, nutritional science, and environmental implication using metrics compiled from industry financial and market research, consumer sentiment surveys, and empirical scientific research. Through our analysis we realized that our results were rife with contradictions. Consumers often pick non-dairy alternatives for health or environmental reasons, but this choice is often rooted in misinformation. Additionally, it is broadly perceived that alternative milks are the largest challenger to the dairy milk industry. However, the industry has been challenged since before …

Assessing Biochar’S Potential To Curb Salt Pollution In Freshwater Systems, Kristina Tsakos

Undergraduate Research and Engagement Symposium

Road salt pollution in the Great Lakes region has been steadily increasing in aquatic systems due to urban sprawl and road safety concerns. Excessive road salt (measured as Cl- mg/L) impacts water quality adjacent to roadside ecosystems by increasing electro- conductivity and altering soil solution osmotic gradients, thus rendering habitats inhospitable for native plants and animals. To date, few mitigation strategies exist to manage salinity in freshwater streams, lakes, and wetlands. Biochar, the by-product of heating organic waste in low oxygen environments, has gained attention as a soil amendment that improves terrestrial systems with degraded agricultural and saline soils. Biochar …

The Homing Abilities Of Nesting Male Threespine Stickleback, Marielle Martin

Undergraduate Research and Engagement Symposium

Homing, a behavior demonstrated by the threespine stickleback allows an organism to return to their home site when displaced. We predicted that male stickleback fish would home well because they guard their young in nests and have high incentive to return. Here we marked and displaced nesting male stickleback over a variety of distances to see whether homing ability declines with distance displaced. Our results show that stickleback can home, but there was no significant relationship between the distance and return rate. However, some nests were taken over by new males after displacement, meaning that even if the experimental fish …

Ecoracism And Antiracism In The Environmental Justice Movement And Their Place In Literature, Jill Amari

Academic Festival

The term “ecoracism” has recently entered the fields of environmental activism, ecocriticism, and Critical Race Theory, though not much research on ecoracism has yet been done in the latter two fields. Antiracism, another modern concept, refers to the acknowledgment of racism and the promotion of racial equality. This paper explores how ecoracism and antiracism are important within the environmental justice movement, just as they are significant in literature. But how can looking at nature literature through an ecoracist and antiracist lens help future studies of these subjects, as well as future environmental and literary scholars? Scholars, like activists, have a …

An Analysis Of The Psychology Surrounding Fan Culture In The Music Industry And Its Effects On Marketing On Social Media, Taylor Barone

Academic Festival

The concept of fan culture in the music industry is not new to American culture. Fan groups have been around for a while, which can be referred to devoted fans showing their love and going to greater length to express their admiration of their favorite artists more than the average person. Actions of fan groups to show their adoration included buying concert tickets and merchandise to creating fan art and starting fan clubs, all to convey the emotional connection they have developed with certain music or musicians. These behaviors are still very much prevalent today, however, with the rise of …

The Catalepsy Of Poetry In America, Titan Wiles

Academic Festival

More poetry than ever is written and published in media outlets now than at any point over the last century, yet the genre appears to possess both less social impact and be given less attention by the wider American information-consumer. William Shakespeare and Robert Frost are well-known names by a majority of the American public, but how many can name a contemporary like Ocean Vuong? This paper follows the trends of nineteenth-century poetic composition and media consumption so as to quantify whether the artform is a dying artifact or if it can endure to a new age and its technology.

Tessellations Around The World, Julia Simoneau

Academic Festival

Tessellations are a well-known concept seen all over the world. They are the notion of one or more geometric shapes being repeated several times on a plane with no gaps or overlaps. They are often seen in art, architecture, computer science, mapping, and more. There are also a few different varieties of tessellations, where some are more intricate than others. For example, the Voronoi tessellation is a special tessellation formed from a set of finite points on the Euclidean plane. Each of these finite points is called a seed which corresponds to a polygon, a Voronoi cell, which contains all …

Adherence To The American Heart Association's Life's Essential 8 In Young African American Women, Zachary Wilder, Kimberly Garcia, Shalan John, Sophana Srisak, Sarah Eisouh, Sparkle Springfield

Undergraduate Research and Engagement Symposium

African American women have the highest burden of cardiovascular disease compared to women of other racial and ethnic groups. The American Heart Association (AHA) developed the Life’s Essential 8 (LE8) to promote ideal cardiovascular health. No known studies have examined adherence to the AHA’s Life’s Essential 8 in young African American women. Based on AHA’s definitions of ideal cardiovascular health, we operationalized the LE8 strategies into a quantitative score and assessed young African American women's adherence.