Digital Commons Network^™

Sex And Environmental Effects On Chemical Signals Of Gryllus Rubens, Marion Davis Creech Iii, Marion Davis Creech Iii

Honors College Theses

Many animals communicate with one another in the context of reproduction, utilizing different modalities. In some cases, more than one modality is used by the sender and receiver. Each modality can provide different sets of information, or function in a different context. Importantly, no matter the modality, the signals should be clearly distinguishable between males and females and need to be reliable even in the face of environmental changes.

In field crickets, there are two major modes of communication. For long-range communication, the males produce acoustic signals to attract females. At short-range, chemical communication involving cuticular hydrocarbons (CHCs) in males …

Healthy Grocery Shopping Experience Via Augmented Reality, Mengjia Isabelle Qiu

Theses

This paper presents how augmented reality can facilitate the modern grocery shopping experience in a fast-paced environment. Grocery shopping customers are facing several problems. Firstly, filtering necessary information by eyes while shopping in grocery stores. Secondly, being distracted by overwhelming information leads to time-consuming deviation in an unfamiliar shopping environment. Thirdly, losing track of purchased food at home and buying the same ingredient repeatedly. Fourthly, neglecting ingredient lists that contain allergic or unhealthy food. To solve these problems, increase the efficiency of decision-making, and achieve shopping goals, this project aims to utilize augmented reality as the primary tool to complete …

The Business Judgment Rule, The Public Interest Powers, And The “Fair And Reasonable” Test: Fellow Travellers Or Ships In The Night?, Jeffrey Macintosh

Osgoode Hall Law Journal

In the most controversial corporate transaction in Canadian history, Magna repurchased all of the Class B superior voting shares from its controlling shareholder, Frank Stronach, at a 1799 per cent premium to the otherwise identical but inferior voting Class A shares, thus ending Stronach’s long reign as de jure controller of Magna. Despite this massive and unprecedented premium, the transaction generated about three billion US dollars in aggregate value, or about 40 per cent of the pre-transaction market cap of Magna. I nonetheless argue that the transaction was massively flawed from both a procedural and substantive point of view and …

Behavioral Economic Demand: Investigation Of Sex Differences In Four Core Genotype Model Of Oral Oxycodone Self-Administration, Michelle Elsmore, David Jentsch, Joshua Peck, Anushree Karkhanis

Undergraduate Honors Theses

Opioid misuse has been identified to be related to problematic release of dopamine in the brain that is otherwise satiated by other alternative rewards. As mediated by patterns of positive and negative reinforcement, prolonged opioid use may transition into misuse and development of opioid use disorder. In human populations, men and women differ in their acquisition of drug use and escalation to drug misuse. Women quickly surpass their male counterparts in their transition from use to misuse in what is coined the telescoping effect. In this four core genotype model of oral oxycodone self administration, males were hypothesized to consume …

2023 North Haverhill Fair 4-H Animal Information Packet, Extension

UNH Cooperative Extension

No abstract provided.

A Model Study To Evaluate Osseointegration And Fracture Healing Following Open Reduction And Internal Fixation (Orif) In Diabetic Lewis Rats, Alexandra Arteaga, Claudia Biguetti, Bhuvana Lakkasetter Chandrashekar, Jimena Mora, Adeena Qureshi, Evelin Rios, Javier La Fontaine, Danieli C. Rodrigues

School of Podiatric Medicine Publications

There is a higher risk of implant osseointegration failure after open reduction and internal fixation (ORIF) in patients with diabetes due to increased inflammatory conditions, associated metallic corrosion and infection. While it is possible to avoid elective osseous surgery in patients with diabetes, it may not be the case in nonelective cases, such as ORIF ankle fractures. A total of 30 male Lewis rats (12-15 weeks old) were distributed into diabetic (D) and nondiabetic (ND) groups. Fracture healing and osseointegration were evaluated at 2-, 10-, and 21-day time points. Microtomographic and histological analysis depicted distinct differences in fracture healing …

Enabling The Intellectually Disabled Mind Through Architecture, Edward J. Voorhees Iv

Bachelor of Architecture Theses - 5th Year

According to the World Health Organization, roughly 10% of the world population live with mental disability or impairment (Fujira, 2005). For the intellectually disabled, finding a purpose and independence as one transitions into yound adulthood can prove troublesome given their unique shortcomings. In 2015, it was estimated 80,000 intellectually disabled adults were held on waiting lists for residential placement in government-funded programs that could take up to 10 years to complete. Autism Speaks approximates that this number will increase by half a million in that same time span (Lutz, 2015). A greater initiative must take place to assist these individuals …

Mutualism In Architecture, Tj Rottenberg

Bachelor of Architecture Theses - 5th Year

Mutualism is a term more commonly used in Ecology and can be defined as the relationship between organisms of differing species in which each benefit. In Architectural terms, Mutualism can be defined as the relationship between differing owners, buildings, typologies, or programs in which each benefit. A relationship already exists in many forms, but not always in a mutually beneficial way. I propose that architecture be designed and built in such a way that physical architecture relates to its surrounding infrastructure in such a way that creates a system or an ecosystem that is mutually beneficial.

In nature there are …

Architecture And Harm Reduction : An Unconventional Approach To Detox, Anna Studdard

Bachelor of Architecture Theses - 5th Year

Harm reduction is a principle that stems from countries like Denmark and Switzerland, that implements strategies to encourage safer drug usage, abstinence, and education for users. The National Harm Reduction Coalition implements nationwide programs for substance abusers, such as Syringe Service Programs, rehabilitation programs, detox programs, housing programs, drug testing facilities, services assisting sex workers, and administering Narcan for overdoses, to try to minimize some of the tragedies accompanying substance abuse. The counterpoint opinion of some countries or states is that providing services like needle exchanges and testing centers are encouraging drug usage and doing more harm than good. However, …

Chattahoochee River Front Design: Sustaining A Lost Culture Through Environmental And Social Stewardship Of Native American, Dalvin Ross

Bachelor of Architecture Theses - 5th Year

How vital is Native American culture in understanding the history and synergy between the social, natural, and built environments? The identity of indigenous people in North America has been stripped and forgotten over years. It is critical to promote rediscovering their ideologies through the establishment of a cultural center which features the architectural contributions of the Native Americans. This undergrade thesis focuses on the city of Atlanta, which has cultural remnants of the first inhabitants of this land. Still, it’s relevance in the community or architecture in Georgia is often overlooked. The Chattahoochee River is a natural tourist attraction, located …

Re . Visiting The Machine For Living, Vincent Ramos

Bachelor of Architecture Theses - 5th Year

The human body’s neurology system is a center piece of the body’s complex communication network. This thesis problematizes the notion of an architecture derived of a ubiquitous ordering system to create kinetic spaces that [inter] . react to an inhabitant as one experiences and moves through physical form and space. By understanding the composition and function of the neurology in the human body, I propose a unique study of the relevance of how the human body works and uses architecture as a systematic interrogation through a series of two-dimensional and three-dimensional diagram explorations. The approach of this research and interrogation …

Afrofuturisms : Ecology, Humanity, And Francophone Cultural Expressions, Isaac Vincent Joslin

Ohio University Press Open Access Books

An exploration of Francophone African literary imaginations and expressions through the lens of Afrofuturism

Generally attributed to the Western imagination, science fiction is a literary genre that has expressed projected technological progress since the Industrial Revolution. However, certain fantastical elements in African literary expressions lend themselves to science fiction interpretations, both utopian and dystopian. When the concept of science is divorced from its Western, rationalist, materialist, positivist underpinnings, science fiction represents a broad imaginative space that supersedes the limits of this world. Whether it be on the moon, under the sea, or elsewhere within the imaginative universe, Afrofuturist readings of …

2023 North Haverhill Fair 4-H Exhibit Hall Information Packet, Extension

UNH Cooperative Extension

No abstract provided.

Fabrication Methods And Chronic In Vivo Validation Of Mechanically Adaptive Microfluidic Intracortical Devices, Youjoung Kim, Natalie N. Mueller, William E. Schwartzman, Danielle Sarno, Reagan Wynder, George F. Hoeferlin, Kaela Gisser, Jeffrey R. Capadona, Allison E. Hess-Dunning

Faculty Scholarship

Intracortical neural probes are both a powerful tool in basic neuroscience studies of brain function and a critical component of brain computer interfaces (BCIs) designed to restore function to paralyzed patients. Intracortical neural probes can be used both to detect neural activity at single unit resolution and to stimulate small populations of neurons with high resolution. Unfortunately, intracortical neural probes tend to fail at chronic timepoints in large part due to the neuroinflammatory response that follows implantation and persistent dwelling in the cortex. Many promising approaches are under development to circumvent the inflammatory response, including the development of less inflammatory …

Angiotensin Ii Receptor Inhibition Ameliorates Liver Fibrosis And Enhances Hepatocellular Carcinoma Infiltration By Effector T Cells, Li Gu, Yahui Zhu, Maiya Lee, Albert Nguyen, Nicolas T Ryujin, Jian Yu Huang, Shusil K Pandit, Shadi Chamseddine, Lianchun Xiao, Yehia I Mohamed, Ahmed O Kaseb, Michael Karin, Shabnam Shalapour

Faculty, Staff and Student Publications

Although viral hepatocellular carcinoma (HCC) is declining, nonviral HCC, which often is the end stage of nonalcoholic or alcoholic steatohepatitis (NASH, ASH), is on an upward trajectory. Immune checkpoint inhibitors (ICIs) that block the T cell inhibitory receptor PD-1 were approved for treatment of all HCC types. However, only a minority of HCC patients show a robust and sustained response to PD-1 blockade, calling for improved understanding of factors that negatively impact response rate and duration and the discovery of new adjuvant treatments that enhance ICI responsiveness. Using a mouse model of NASH-driven HCC, we identified peritumoral fibrosis as a …

Meeting The Jche Team: A Reconstructed Interview, Heesoon Bai, Charles Scott, Cary L. Campbell, Jwalin Patel, Yifan Sun, Jing Lin, Hyeyoung Bang, Sachi Edwards, Deepa Srikantaiah, Yishin Khoo, Denise L. Mchugh

Journal of Contemplative and Holistic Education

This “reconstructed interview-conversation” involves the entire editorial team of the Journal of Contemplative and Holistic Education (JCHE). Together, the team dialogues around the shared visions, aspirations, motivations, and aims we have in creating this new journal platform. With this sharing, the team sends out a welcoming invitation to colleagues from around the world to get to know our new journal and to join our work to support and promote contemplative and holistic education. We at JCHE are committed to the ideal of education as transformative integration of mind-body-heart-spirit, which we ultimately understand as a decolonizing project. Through this interview, various …

Navigating The Free Trade—Fair Trade Fault-Lines By Michael Trebilcock, Nicholas Slagter

Osgoode Hall Law Journal

The COVID-19 pandemic came with several revelations about our pre-pandemic lives. One of these revelations was the importance of international trade law in the lives of average individuals. Headlines about food supplies, shortages of essential medical supplies, and countries’ plans to acquire and produce vaccines dominated the media following March 2020. It was a time that spurred the public’s interest in international trade law and how it functions. Indeed, media headlines showcased the growing concern about international trade during the pandemic. This is the context in which Michael Trebilcock’s Navigating the Free Trade—Fair Trade Fault-Lines situates itself. At a time …

Leveraging Neutrosophic Uncertainty Theory Toward Choosing Biodegradable Dynamic Plastic Product In Various Arenas, Mona Mohamed, Karam M. Sallam

Neutrosophic Systems with Applications

Numerous studies in recent years have documented the negative effects of plastic waste on the environment and human wellness. Due to their widespread usage in daily life, particularly in packaging, and their rising direct or indirect discharge into the environment, plastics are recognized as an emerging environmental hazard. Thus, this point is considered the first problem in this study. As a result, efforts to replace traditional plastics with bioplastics have intensified. However, studies regarding the effects of conventional and bioplastics (BioPs) are also important. Hence, biodegradable polymers for industrial and commercial usage are essential in the present day as an …

Activating Non-Place, Noah Stogner

Bachelor of Architecture Theses - 5th Year

Marc Augé defined non-place as the typical area in the urban space that has lost its identity and thus has fallen into the banal. Some of these typical nonplaces include airports, hotel rooms, convenience stores, and shopping malls. Augé argues that our urban space is ridden with these infrastructural inserts that lack of uniqueness and are homogeneous in nature. This lack of uniqueness has evolved into a mass exodus of urban interaction resulting in the identity of a city becoming lost. Auge’s nonplace are evident in our urban and suburban environments. On the other hand, Kevin Lynch defines the city …

Mechanisms Underlying The Antiarrhythmic Effect Of Arumenamide-787 In Experimental Models Of The J Wave Syndromes And Hypothermia, José M. Di Diego, Hector Barajas-Martinez, Robert Cox, Victoria M Robinson, Joseph Jung, Mohamed Fouda, Mena Abdelsayed, Peter C Ruben, Charles Antzelevitch

Department of Medicine Faculty Papers

BACKGROUND: Brugada (BrS) and early repolarization syndromes (ERS), the so-called J wave syndromes (JWS), are associated with life-threatening ventricular arrhythmias. Pharmacologic approaches to therapy are currently limited. In this study, we examine the effects of ARumenamide-787 (AR-787) to suppress the electrocardiographic and arrhythmic manifestations of JWS and hypothermia.

METHODS: We studied the effects of AR-787 on INa and IKr in HEK-293 cells stably expressing the α- and β1-subunits of the cardiac (NaV1.5) sodium channel and hERG channel, respectively. In addition, we studied its effect on Ito, INa and ICa in dissociated canine ventricular myocytes along with action potentials and ECG …

Single-Cell Transcriptome Analysis Of Xenotransplanted Human Retinal Organoids Defines Two Migratory Cell Populations Of Nonretinal Origin, Ying V Liu, Clayton P Santiago, Akin Sogunro, Gregory J Konar, Ming-Wen Hu, Minda M Mcnally, Yu-Chen Lu, Miguel Flores-Bellver, Silvia Aparicio-Domingo, Kang V Li, Zhuo-Lin Li, Dzhalal Agakishiev, Sarah E Hadyniak, Katarzyna A Hussey, Tyler J Creamer, Linda D Orzolek, Derek Teng, M Valeria Canto-Soler, Jiang Qian, Zheng Jiang, Robert J Johnston, Seth Blackshaw, Mandeep S Singh

Faculty, Staff and Students Publications

Human retinal organoid transplantation could potentially be a treatment for degenerative retinal diseases. How the recipient retina regulates the survival, maturation, and proliferation of transplanted organoid cells is unknown. We transplanted human retinal organoid-derived cells into photoreceptor-deficient mice and conducted histology and single-cell RNA sequencing alongside time-matched cultured retinal organoids. Unexpectedly, we observed human cells that migrated into all recipient retinal layers and traveled long distances. Using an unbiased approach, we identified these cells as astrocytes and brain/spinal cord-like neural precursors that were absent or rare in stage-matched cultured organoids. In contrast, retinal progenitor-derived rods and cones remained in the …

Rapid Neuroplasticity Changes And Response To Intravenous Ketamine: A Randomized Controlled Trial In Treatment-Resistant Depression, Jared Kopelman, Timothy A Keller, Benjamin Panny, Angela Griffo, Michelle Degutis, Crystal Spotts, Nicolas Cruz, Elizabeth Bell, Kevin Do-Nguyen, Meredith L Wallace, Sanjay J Mathew, Robert H Howland, Rebecca B Price

Staff and Researcher Publications

Intravenous ketamine is posited to rapidly reverse depression by rapidly enhancing neuroplasticity. In human patients, we quantified gray matter microstructural changes on a rapid (24-h) timescale within key regions where neuroplasticity enhancements post-ketamine have been implicated in animal models. In this study, 98 unipolar depressed adults who failed at least one antidepressant medication were randomized 2:1 to a single infusion of intravenous ketamine (0.5 mg/kg) or vehicle (saline) and completed diffusion tensor imaging (DTI) assessments at pre-infusion baseline and 24-h post-infusion. DTI mean diffusivity (DTI-MD), a putative marker of microstructural neuroplasticity in gray matter, was calculated for 7 regions of …

Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff

LSU Master's Theses

Second-generation antipsychotics (SGAs), such as risperidone, are widely prescribed to children, but the long-term effects of SGA treatment are not well understood. This study investigated the impact of early-life risperidone treatment on sucrose demand in mice in adulthood. Mice were administered risperidone or vehicle from postnatal day (PND) 33 to 60 and trained in adulthood (>PND 120) to nose poke for a sucrose solution reinforcer. The fixed ratio (FR) value (the number of responses required to produce sucrose delivery; the “price” of sucrose) was varied from 1 to 45, and the resulting consumption versus FR value data were analyzed …

Prehistoric Hunter-Gatherers In The Philippines—Subsistence Strategies, Adaptation, And Behaviour In Maritime Environments, Alfred Pawlik, Riczar Fuentes

Sociology & Anthropology Department Faculty Publications

Archaeological research in the Philippines has produced a timeline of currently over 700,000 years of human occupation. However; while an initial presence of early hominins has been securely established through several radiometric dates between 700 ka to 1ma from Luzon Island; there is currently little evidence for the presence of hominins after those episodes until c. 67 to 50 ka for Luzon or any of the other Philippine islands. At approximately 40 ka; anatomically modern humans had arrived in the Philippines. Early sites with fossil and/or artifactual evidence are Tabon Cave in Palawan and Bubog 1 in Occidental Mindoro; the …

The Fear Of The Unknown, Kacper Kwidzinski

COD Library Student Research and Award Symposium

My paper titled, “The Fear of the Unknown” explores the intricate world of fear and anxiety, and gives an answer to the question, “Why do humans have such a profound fear of the unknown?” In this paper, I explain the differences between fear and anxiety, what makes certain fears fundamental, and lastly, how the fear of the unknown influences our day to day lives.

Faculty Sponsor: Professor Kelly Kristof

The Effect Of Scenario-Based Learning On 8th Grade Students’ Perceptions Of Scientists, Fatma Şaşmaz Ören, Ayşegül Karapinar, Kübranur Sari, Tuğba Demi̇rer

Journal of Educational Research and Practice

The aim of our study was to investigate the effect of scenario-based learning on eighth-grade students’ perceptions of scientists. We used a semiexperimental design to conduct our research with 36 students from the eighth grade, who were divided into experimental and control groups. We collected the data through a “Draw-a-Scientist Test,” an opinion form, and semistructured interviews. According to the findings we obtained from the drawing test, students have stereotypical perceptions of the scientists’ working environment (indoor/laboratory). But the results showed that scenario-based teaching affects eighth-grade students’ perceptions of scientists and moves them forward on two points: (1) the physical …

Agricultural Nutrient Pollution In The Mississippi River Basin, Grace Weber

COD Library Student Research and Award Symposium

The nutrients nitrogen and phosphorus harm the Mississippi River Basin. Entering waterways from Midwestern farms, the nutrients flow down the Mississippi River and create large algal blooms. Algal growth can severely reduce or eliminate the amount of dissolved oxygen in the water. The lack of dissolved oxygen makes the majority of marine life die or become ill. This creates “dead zones” as seen in the Gulf of Mexico. Nutrient pollution affects human health, the environment, and the economy. By eating a more plant-based diet, working with farmers, and holding polluters accountable, nutrient pollution can be reduced to create safer waters.

Single-Use Plastics In The Ocean, Kathryn Sievers

COD Library Student Research and Award Symposium

How do plastics impact the ocean environment through the Great Pacific Garbage Patch and how can individual households reduce their single-use plastic usage? I studied this question to understand the journey of single-use plastics to the Great Pacific Garbage Patch (GPGP) and their effects on the environment and marine animals while also finding actions households can take to reduce the amount of plastics being dis posed of in order to reduce the size of the Patch in the ocean.

Faculty Sponsor: Professor Laura Burt-Nicholas

Faculty Sponsor: Professor Shamili Ajgaonkar

The Law Of Equitable Distribution: When Is Domestic Violence More Than Just A Factor In Divorce?, Ada Tonkonogy

Journal of Civil Rights and Economic Development

(Excerpt)

Imagine you are married. After many years there are problems in your marriage. Some of these issues are beyond your control. You find out that your spouse is cheating on you. You plan to come home from work and confront your spouse about their infidelities. You even begin to think about the divorce process, confronting the concerns raised in your mind. I’ll be okay. I have a great career, I have worked my entire life, and I have saved. I will be okay.

That night you approach your spouse. After an argument breaks out, you tell your spouse that …

Modelling Filter Response Of Galactic Emission Line Spectra, Jessica Johnson, Christian Draper

Utah Space Grant Consortium

The overall goal of our research is to begin to make a map of the universe in order to find evidence for the cold dark matter theory. Dark matter, which is 85% of all matter, does not interact with light, making it invisible to telescopes. However, we know it exists due to its gravitational effects on visible matter, which can be hard to detect.