Digital Commons Network^™

Fight To Ignite: The Impacts Of Climate Change On Prescribed Burning In Pine Forests, Chloe Anderson

Celebrating Scholarship and Creativity Day (2018-)

Prescribed burning is a strategy that has been used to manage the health of forest ecosystems for thousands of years. While these practices have certainly evolved over time, recent impacts of climate change are threatening the future feasibility of implementing fire in forest management altogether. This ecological process is essential to restoring and maintaining a healthy forest ecosystem as fire acts as a catalyst by returning nutrients to soil and promoting healthy regrowth. Prescribed burning prepares forestlands for reforestation by destroying weeds and other competitive species so that native and fire-dependent species can reproduce. This process also lessens the fuel …

Communicating Across The Pond: Evaluating Perceptions Of Dialectal Divergence Among American Student Sojourners In England, Katherine T. Peppiatt

Senior Honors Projects, 2020-current

Although at first glance the differences between British English and American English seem trivial, “apartment” vs. “flat” or “color” vs. “colour," these dialectal divergences immediately create an othering effect. Subtle changes are representative of the deeper implications of this issue; altered language impacts perceptions about the validity and correctness of a written work. My research seeks to understand how the differences between British English and American English impact American student sojourners during an abroad experience in England. Examining how American sojourners perceive dialectal differences and adapt their written rhetoric to match that of a British audience offers valuable insight into …

The Role Of Powers In Pādas Iii And Iv In The Yogasūtra Of Patañjali: Realities And Implications, Mathilde Peña

LMU Theses and Dissertations

This paper discusses the realities and implications of the framework for siddhis as outlined in pādas III and IV of the Yogasūtra of Patañjali, and the impact of the Western Protestant hermeneutical lens on the dismissal or negative treatment of siddhis within many schools of Modern Yoga. Contending for the possibility of the supernatural or paranormal, this project will explore the transformative potential of yoga using that framework to discuss the need for new metaphors which contain space for the dance between form and formless present within Sāṃkhyan metaphysics. It will discuss the idea of embodied metaphors and how yoga …

Who’S Bringing The Fungi?, Nicolas Gosling

UNH Today Archive

No abstract provided.

A Conditional Strategy For Cell-Type-Specific Labeling Of Endogenous Excitatory Synapses In Drosophila, Michael J. Parisi, Michael A. Aimino, Timothy J. Mosca

Farber Institute for Neuroscience Faculty Papers

Chemical neurotransmission occurs at specialized contacts where neurotransmitter release machinery apposes neurotransmitter receptors to underlie circuit function. A series of complex events underlies preand postsynaptic protein recruitment to neuronal connections. To better study synaptic development in individual neurons, we need cell-type-specific strategies to visualize endogenous synaptic proteins. Although presynaptic strategies exist, postsynaptic proteins remain less studied because of a paucity of cell-type-specific reagents. To study excitatory postsynapses with cell-type specificity, we engineered dlg1[4K], a conditionally labeled marker of Drosophila excitatory postsynaptic densities. With binary expression systems, dlg1[4K] labels central and peripheral postsynapses in larvae and adults. Using dlg1[4K], we find …

The Effect Of Cannabinoids And Terpenes On The Activation Of Hmc3 Microglial Cells, Mohamed Marzouk

Honors Theses

Life expectancies of people living with HIV have significantly lengthened due to the availability of antiretroviral therapies. Despite their ability to increase survival, these treatments do not “cure” HIV, nor do the stop the onset of neurological symptoms associated with infection, termed neuroHIV. NeuroHIV describes a myriad of neurological impairments including mood disorders (depression and anxiety), cognitive impairment, neuropathic pain, and motor disinhibition that reduce quality of life for people living with HIV. Mechanistically, the neurological impairments may involve actions of neurotoxic proteins directly produced by the virus. One of these proteins that has been well-characterized is the HIV trans …

Developing Genotypic And Phenotypic Systems For Early Analysis Of Drug-Resistant Bacteria, Yesman Akuoko

Theses and Dissertations

Antimicrobial resistance in bacteria is a global health challenge with a projected fallout of 10 million deaths annually and cumulative costs of over 1 trillion dollars by 2050. The currently available tools exploited in the detection of bacteria or their DNA can be expensive, time inefficient, or lack multiplex capabilities among others. The research work highlighted in this dissertation advances techniques employed in the phenotypic or genotypic detection of bacteria and their DNA. In this dissertation, I present polymethyl methacrylate-pressure sensitive adhesive microfluidic platforms developed using a time-efficient, inexpensive fabrication technique. Microfluidic devices were then equipped with functionalized monoliths and …

Health Professional Well-Being And Preparedness During The Covid-19 Pandemic In Trinidad And Tobago: An Online Survey, Loren De Freitas, Darren Dookeeram, Shastri Motilal

Journal of Wellness

Introduction: Poor well-being impacts mental health and subsequently affects personal lives, leads to absenteeism, poor productivity, and compromised patient safety. Frontline healthcare workers are highly vulnerable to COVID-19 pandemic-related mental health strain. This study assessed the well-being and preparedness of frontline healthcare workers in Trinidad and Tobago during the pandemic.

Methods: An online cross-sectional survey was sent to doctors, nurses, and prehospital providers from public and private healthcare sectors. Data was collected from May to June 2020 utilizing a self- administered online platform. The WHO Five Well-being Index (WHO-5) was used to assess well-being. Raw scores less than 13 indicated …

The Opioid Epidemic: How Genetics Play A Role In Addiction And Treatment, Kirsten Houston

Honors College Theses

The opioid epidemic is an issue within the pharmaceutical industry in the United States of America due to prescription and non-prescription substances being made available to the population. Opioids include chemical substances that affect the body and brain through opioid receptors, including the mu, kappa, and delta receptors. These substances are derived and synthesized from the poppy plant. Multiple causes have been linked to opioid abuse disorder, including but not limited to employment, income, housing, nutrition, mental health disorders, and genetics. By gathering information from previous literature, genetics may be the main cause of narcotic analgesic tolerance and abuse. Specific …

Cenabis Bene: A Culinary Odyssey Through Apicius, Kathryn Atkinson

Honors Scholar Theses

Apicius is the sole surviving cookbook from classical antiquity; as such it is invaluable for what it tells us about ancient feasting customs. Yet the gluttony typically associated with classical antiquity has no place in Apicius beyond the art that is inherently associated with food; we are not so much given a seat at the cena (dinner) as we are led into the kitchen, handed an apron, and instructed to cook. This critical analysis explores each recipe not only on the surface—i.e., examining the ingredients and recreating selected recipes—but also on a deeper level, lifting food above its concrete reality …

Freckled Darter (Percina Lenticula) And Other Fishes’ Usage Of Wood Pile Habitat, Noah Daun

Master's Theses

Effectively sampling habitat with the proper techniques is essential for our understanding of the animals that use the habitat, both for individual species and entire species assemblages. Percina lenticula is a species of special concern in the state of Mississippi due to low numbers of historical records. This species is known to inhabit wood pile habitat in rivers, a habitat that has been under-sampled historically due to inefficiency with most commonly used gear. Seines are typically not effective at sampling wood piles, resulting in sampling bias underestimating the number of P. lenticula and potentially other species utilizing such habitats. This …

Comparative Analysis Of Rhizosphere And Endosphere Microbiome Of Different Blueberry Species (Vaccinium Sp.), Niladri Bhowmik

Master's Theses

Blueberries are an important agricultural commodity in all over the United States. Due to its health benefits, there is a huge demand globally, thus expanding the industry. Breeding programs are essential to maintain such industries. Challenges that play a role in contemporary breeding programs are various biotic and abiotic stress factors. Studies have shown that microorganisms are recruited by plants to alleviate them during stressful conditions. Though blueberries have been cultivated for about 100 years, how the microbiome has been affected due to this is poorly understood. We hypothesized that interspecific crosses and artificial selection have significantly changed the microbiome …

Ramie (Boehmeria Nivea): An Underutilized Plant For A Multipurpose Industrial Application; A Perennial Plant With Protein Identification Using Maldi-Ms, A Biosorbent For Hg (Ii) Removal From Water And As A Bast Fiber Production Via Enzymatic Degumming, Abdul Rashid Issifu

Master's Theses

Identifying plant species that can offer life support to humans and animals without damaging the environment is quite challenging. Ramie, one of the oldest fiber crops was studied due to its nutritional value as fodder and other multipurpose applications in, e.g., medicinal, environmental, and textile industrial fields.

With a brief discussion of background in Chapter I, Chapter II focused on using a proteomic method to investigate unknown proteins in the leaves of ramie and to study their benefits to the biological system. PPiase and RuBisCO with molecular weight 15 and 52 KDa were identified as the proteins after peptide mass …

Bold Ideas, Better Outcomes, William Ewing

UNH Today Archive

No abstract provided.

Soil Respiration Measurements Reveal High Retention Of Organic Carbon From Corn Residue Derived High-Lignin Fermentation Byproduct Enabling Sustainable Lignocellulosic Biofuel Production, Michelle Sun Wang

Dartmouth College Master’s Theses

While 2G biofuel production can utilize non-edible, lignocellulosic feedstocks such as agricultural residues to produce liquid fuel, harvesting crop residues is unsustainable without careful management of the soil underneath. By harvesting a fraction of the crop residues left in the field after harvest, soil health can diminish and critically, the soil organic carbon (SOC) stored in agricultural fields can decrease. Currently, in the most popular 2G process models published, the issue of soil degradation remains unresolved with residue harvest strategies receiving considerable attention in the literature and other SOC management strategies receiving far less. Specifically, the strategy of returning the …

The Effect Of Microglial Cell Dysfunction On Multi-Modal Pre-Pulse Inhibition, Michelle Besser

Dissertations, 2020-current

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication, restricted behaviors, and executive functioning deficits. Mutations in fractalkine signaling, particularly in CX3CR1, in the brain have been linked to ASD and other neurodevelopmental disorders. This investigation examined wild-type mice and mice with one or two copies of mutated CX3CR1 and their uni-modal (auditory and somatosensory) and multi-modal (combined) pre-pulse inhibitions (PPI). PPI is an unconditioned response – a decrement in the acoustic startle reflex when the mouse detects a non-startling stimulus presented a few hundred ms before the startling sound. In this study, the …

Observing How College Students Process Culturally Responsive Test Items, Chris R. Patterson

Dissertations, 2020-current

Typical approaches to test and item development are rooted in the Standards for Educational and Psychological Testing. Culturally responsive and antiracist assessment practices are two new processes that challenge the typical process noted in the Standards, incorporating critical race theory and cultural responsiveness into the item development process. Given these two approaches are relatively new, there is minimal research on how test takers process and comprehend test items created using these approaches.

This dissertation modified multiple-choice test items through the lenses of cultural responsiveness and antiracism to create two sets of item types (diversity-infused and sociopolitical consciousness; DI and …

Impact Of Diabetes Mellitus On Vestibular Function: A Scoping Review, Ellen M. Jones

Dissertations, 2020-current

Diabetes mellitus (DM) encompasses a group of metabolic diseases that result in high blood sugar (i.e., hyperglycemia). By 2030, it is anticipated that 578 million adults worldwide will have DM, with this number growing at a faster rate in developed areas of the world.^[27] If left uncontrolled, DM can cause considerable damage to several areas of the body, including the heart, kidneys, nerves, and ears. When focusing exclusively on the ears, there has been markedly less research on the vestibular system when compared to the auditory system, even though DM is a known risk factor for falling. The purpose …

Age-Related Decline In Neural Synchrony And The Ffr, Haley Szabo

Dissertations, 2020-current

It is a known phenomenon that speech understanding in background noise declines with advancing age. Although there is ample evidence of behavioral measures declining with age, there is less physiologic evidence. This study hypothesizes that the FFR will be degraded with advancing age, consistent with poorer phase locking. This is hypothesized to be present even in people with audiograms within normal limits. A second hypothesis is that middle-aged adults will have degraded neural representation as frequency increases, compared to a younger normal hearing group which will have better high frequency neural representation than the middle-aged group. Subjects were divided into …

Locomotion And Life History In A Leaping Primate: Mechanics And Energetics Of Movement Throughout The Propithecus Lifespan, Nicholas Heslep

Masters Theses, 2020-current

Arboreal primates are typically altricial, exhibit long juvenile periods, and use dynamic locomotor behaviors that can be challenging and risky. Sifaka (Propithecus verreauxi) have particularly slow life histories for their size, with long juvenile periods, protracted reproductive careers, and long life spans. Slow somatic growth poses potential mechanical challenges for juvenile sifaka who use thigh-powered vertical clinging and leaping to follow group members during travel. I examined mechanical and energetic costs of movement in developing sifaka. I instrumented 8 wild sifaka (3 yearlings, 3 subadults, 2 adults) in 4 social groups with inertial sensors measuring tri-axial acceleration for …

The Response Of Microcystis And The Microbiome To Exogenous Hydrogen Peroxide, Bryan A. Puma

Masters Theses, 2020-current

Microcystis spp. produce prolific annual blooms in freshwater systems worldwide. The success of these blooms depends heavily on the Microcystis spp. overcoming environmental factors such as oxidative stress caused by reactive oxygen species (ROS) like hydrogen peroxide. Most Microcystis genomes do not contain many genes for responding to oxidative stress, including those that encode the enzyme catalase. Other cyanobacteria such as Prochlorococcus that also lack hydrogen peroxide degrading enzymes have been shown to benefit from partnerships with heterotrophic bacteria. Microcystis spp. may also receive similar benefits from heterotrophic bacteria in the phycosphere. To test this hypothesis, we examined the …

Characterizing The Effects Of Light On The Early Onset Photoreceptor Function Loss In Mucolipidosis Type Iv, Rebecca Cistulli

Masters Theses, 2020-current

Retinal degenerative diseases (RDD’s) are a diverse group of retinal disorders that cause visual impairment. While RDD prevalence is high, little is known about the molecular mechanisms underlying the pathogenesis within some of these disorders. Here we are trying to elucidate the molecular mechanisms that drive early onset photoreceptor function loss in the RDD, Mucolipidosis type IV (MLIV). MLIV is a lysosomal storage disorder that results from loss of function mutations in the MCOLN1 gene and leads to a disruption of autophagy. The MCOLN1 gene encodes a lysosomal cation channel called Trpml1. Based on previous data from our lab, we …

All The Rage: Assessing The Age/Rage Signaling Pathway’S Effects On Healthspan And The Physiological Processes Of Aging, Brandon Ashmore

Honors Theses

Advanced glycation end products (AGEs) are protein, lipid, or nucleotide molecules that have been combined with sugars through nonenzymatic, irreversible glycation and oxidation reactions. Their accumulation in the body has been associated with the natural aging process and a wide range of pathologies, including chronic inflammation, sustained oxidative stress, diabetes, neurodegenerative diseases, atherosclerosis, and cancer. Their interaction with the receptor for advanced glycation end products (RAGE) has been linked to several proinflammatory signaling pathways associated with neurotoxicity and vascular lesions. While some research has been done on the possible health benefits of RAGE inhibition to extend lifespan, our study hopes …

Impact Of Creatine Supplementation On Repeated Sprint Performance In Normobaric Hypoxia, Anthony Russomano

Masters Theses, 2020-current

Purpose: The aim of this study was to determine the effect of creatine supplementation (CrS) on repeated sprint performance in both normoxia and normobaric hypoxia (simulated altitude ~3,000 m). Methods: Nineteen recreationally trained cyclists were randomly assigned to one of two groups; one received six days of either CrS (n = 12; 0.3 g/kg of body mass of creatine monohydrate) and the other received six days of placebo (PLA; n = 7; 0.3 g/kg of maltodextrin). All subjects completed separate trials in normoxia (inspired O₂ = 20.93%) and hypoxia (O₂ = 15%) before and after the supplementation …

The Effect Of Training Status On Exercise Performance And Oxygen Uptake Responses To Beetroot Juice Supplementation In Cyclists, Haley Mcvannel

Masters Theses, 2020-current

Purpose: To determine if cardiovascular fitness, assessed by peak oxygen consumption (VO_2peak),influences the physiological and performance effects of beetroot juice (BRJ) supplementation and to explore if recent training habits independently influence this response. Methods: Thirteen male and female cyclists completed two graded exercise tests to assess cardiovascular fitness and four, seven-day experimental phases. Five subjects were classified as high fitness (VO_2peak: 65.9 ± 4.5 mL∙kg^-1∙min^-1) and eight as lower fitness (VO_2peak: 44.2 ± 7.0 mL∙kg^-1∙min^-1). Subjects consumed 140 ml of concentrated BRJ or placebo the last …

Understanding Context Dependent Responses To Climate Change In Arizona Tiger Salamanders (Ambystoma Mavortium Nebulosum), Kentrell Richardson

Masters Theses, 2020-current

Future emissions scenarios project climate change to increase average global temperatures by at least two ℃ in the next 50 years resulting in changes in local climate and causing increased variability within microclimates. Ectotherms are especially sensitive to climate change due to their dependence on environmental temperatures to regulate physiological functions. Changes in temperature are likely to impact thermally cued processes within amphibians and result in changes in variable magnitudes and directions within local populations.

Salamanders were placed in cups and partially submerged in a water bath and heated at a rate of ~0.27℃/ minute. Once salamanders were unable to …

Effects Of Litter Biomass And Soil Stoichiometry On Leaf Litter Amphibian And Reptile Density, Biomass, And Community Structure In Tropical Wet Forests, Alondra Medina Charriez

Masters Theses, 2020-current

Understanding the mechanisms behind patterns of diversity and abundance is a major goal of ecology. Research on nutrient stoichiometry has revolutionized the way ecologists understand the patchy distribution of mega-diverse invertebrate taxa that live at the soil surface and leaf litter in tropical wet forests. In this study, I studied the importance of soil nutrient concentrations and stoichiometry, habitat structure, and invertebrate biomass for patterns of amphibian and reptile density, biomass and community structure in two lowland wet tropical forests. I used data from study sites in Los Amigos Biological Station in Peru and two sampling occasions at La Selva …

Energy Homeostasis In An Extreme Vertebrate: Relationships Between Life-History Status And The Molecular Stress Response In Red-Sided Garter Snakes, Rysa Thomas

Masters Theses, 2020-current

Vertebrates experience diverse and unique life-history events, many of which are annual and energetically taxing. Energy is a limited resource and thus its careful budgeting is critical for successful transitions between life-history states and across the lifetime of a species. Glucocorticoids (GCs) regulate vertebrate energetics via partitioning of energy use and storage in metabolic tissues (liver, fat, muscle) and exert their effects through activation of two main receptor types, the glucocorticoid receptor (GR), responsible for mobilization of energy from storage tissues, and the mineralocorticoid receptor (MR), responsible for ion balance and osmotic homeostasis. Species adapted to extreme environments carefully balance …

Understanding The Regulatory Context And Mechanism Of Hlh-25 Mediated Transcriptional Repression, Dagmawi Mamo

Masters Theses, 2020-current

The HES family of transcription factors are primarily repressors of transcription that play critical roles in mammalian embryogenesis by regulating cell differentiation and proliferation. Proper functioning of HES proteins is crucial in humans, as mutations or misexpression of HES1 is associated with lung, pancreas, colon, and other cancers. HES1 may mediate short-range or long-range repression through DNA-binding and or protein-protein interactions with other factors. However, prior genetic studies have not fully elucidated how the context-specific binding of HES1, or its C. elegans ortholog HLH-25, promotes the repression of transcription. Characterization of the cis-regulatory context and mechanism of HLH-25 mediated repression …

Dirt Circus: Queering Sports And Home Through Filth, Hannah Patteson

Masters Theses, 2020-current

This monograph accompanies the MFA Thesis Exhibition, “Dirt Circus”. I outline the history of circus and carnival culture and the ways in which queer identities are expressed through these artistic modes. I describe the nonconforming expressions of gender in these arenas through bearded ladies, aerialists, clowns, and the freak show. I then explore various groups from the 70’s to present day, including Bread and Puppet Theater, The Cockettes, and Split Britches, who utilize performance to further their ideologies of gender freedom, anti-capitalism, and sexual liberation. I compare our differing uses of cheap art and public engagement within the realm of …