Digital Commons Network^™

Innovator - Spring 2023

Innovator

03 - The President’s Column

06 - Time Machine: Fabric of the Heart

10 - The Nexus: News at Jefferson

20 - Student to #Philebrity: Influenced by Jefferson

24 - The Light Fantastic

30 - We Are One Jefferson

34 - Question & Innovate

36 - Reimagine

40 - Ram Roundup

44 - Class Notes

56 - In Memory

58 - Trivia

Noninvasively Monitoring Of Cerebral Blood Flow In Piglet Models Of Graded Hemorrhage And Hypoxic Ischemic Brain Injury Using Diffuse Correlation Spectroscopy And Near-Infrared Spectroscopy, Randolph Sinahon, Danielle Shoshany, Shadi Malaeb, Mert Deniz Polat, Meltem Izzetoglu, Kurtulus Izzetoglu

St. Chris Research Day

No abstract provided.

Cerebral Blood Flow Measured By Diffuse Correlation Spectroscopy For Monitoring Depth Of Anesthesia In Piglets, Mert Deniz Polat, Kurtulus Izzetoglu, Randolph Sinahon, Meltem Izzetoglu, Shadi Malaeb

St. Chris Research Day

No abstract provided.

Cardiovascular Responses During Light-Intensity Aerobic Exercise With Varying Levels Of Limb Occlusion Pressures., William R. Vanwye, Alyssa M. Weatherholt, Lee J. Winchester, Johnny G. Owens, Micah Spears

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 676-687, 2023. The study aimed to assess cardiovascular responses to low-intensity aerobic exercise with varying levels of limb occlusion pressures (LOP) in a healthy population of men and women 30 to 60 years. The study was a single-session repeated measures design. Thirty individuals completed the study. All subjects participated in a single bout of low-intensity cycling (30-39% HRR) with bilateral lower extremity (LE) BFR for four 5-minute stages [0% (No BFR), 40%, 60%, and 80% LOP] with a 2-minute active rest between stages (BFR pressure released). The subjects’ systolic blood pressure (SBP), diastolic blood …

Rehybridization Dynamics Into The Pericyclic Minimum Of An Electrocyclic Reaction Imaged In Real-Time, Y. Liu, D. M. Sanchez, M. R. Ware, E. G. Champenois, J. Yang, J. P. F. Nunes, A. Attar, Martin Centurion, J. P. Cryan, R. Forbes, K. Hegazy, M. C. Hoffmann, F. Ji, M.-F. Lin, D. Luo, S. K. Saha, X. Shen, X. J. Wang, T. J. Martínez, T. J. A. Wolf

Department of Physics and Astronomy: Faculty Publications

Electrocyclic reactions are characterized by the concerted formation and cleavage of both σ and π bonds through a cyclic structure. This structure is known as a pericyclic transition state for thermal reactions and a pericyclic minimum in the excited state for photochemical reactions. However, the structure of the pericyclic geometry has yet to be observed experimentally.We use a combination of ultrafast electron diffraction and excited state wavepacket simulations to image structural dynamics through the pericyclic minimum of a photochemical electrocyclic ring-opening reaction in the molecule α-terpinene. The structural motion into the pericyclic minimum is dominated by rehybridization of two carbon …

Influenza C And D Viruses Demonstrated A Differential Respiratory Tissue Tropism In A Comparative Pathogenesis Study In Guinea Pigs, Chithra C. Sreenivasan, Runxia Liu, Rongyuan Gao, Yicheng Guo, Ben M. Hause, Milton Thomas, Ahsan Naveed, Travis Clement, Dana Rausch, Jane Christopher-Hennings, Eric Nelson, Julian Druce, Miaoyun Zhao, Radhey S. Kaushik, Qingsheng Li, Zizhang Sheng, Dan Dan, Feng Li

Nebraska Center for Virology: Faculty Publications

Influenza C virus (ICV) is increasingly associated with community-acquired pneumonia (CAP) in children and its disease severity is worse than the influenza B virus, but similar to influenza A virus associated CAP. Despite the ubiquitous infection landscape of ICV in humans, little is known about its replication and pathobiology in animals. The goal of this study was to understand the replication kinetics, tissue tropism, and pathogenesis of human ICV (huICV) in comparison to the swine influenza D virus (swIDV) in guinea pigs. Intranasal inoculation of both viruses did not cause clinical signs, however, the infected animals shed virus in nasal …

Issue 418: May 18-June 1, 2023, The Local Voice

The Local Voice

No abstract provided.

European Marine Omics Biodiversity Observation Network: A Strategic Outline For The Implementation Of Omics Approaches In Ocean Observation, Ioulia Santi, Odette Beluche, Mélanie Beraud, Pier Luigi Buttigieg, Raffaella Casotti, Cymon J. Cox, Michael Cunliffe, Neil Davies, Cerio Od De, Katrina Exter, Anne Emmanuelle Kervella, Georgios Kotoulas, Rune Lagaisse, Arnaud Laroquette, Bruno Louro, Fabrice Not, Matthias Obst, Christina Pavloudi, Julie Poulain, Kim Præbel, Jan Vanaverbeke, Nicolas Pade

School of Biological and Marine Sciences

Marine ecosystems, ranging from coastal seas and wetlands to the open ocean, accommodate a wealth of biological diversity from small microorganisms to large mammals. This biodiversity and its associated ecosystem function occurs across complex spatial and temporal scales and is not yet fully understood. Given the wide range of external pressures on the marine environment, this knowledge is crucial for enabling effective conservation measures and defining the limits of sustainable use. The development and application of omics-based approaches to biodiversity research has helped overcome hurdles, such as allowing the previously hidden community of microbial life to be identified, thereby enabling …

Possible Impact Of Additives In Artificial Turf On Aquatic Life In The San Francisco Estuary, Elena Galkina

Master's Projects and Capstones

The use of artificial turf fields as a replacement for natural turf has been increasingly promoted as a green solution to reduce water usage, maintenance costs, and the need for pesticides. However, the potential environmental impacts of artificial turf fields are poorly understood, particularly in the context of the San Francisco Estuary, which is one of the largest and most polluted estuaries in the United States. This paper investigates the potential contribution of artificial turf from sports fields to the microplastic and chemical pollution of the San Francisco Estuary during artificial turf’s use and maintenance life stage. The study synthesizes …

The Use Of Therapeutic Gardening In Addiction Recovery, Sophia Agne

Master's Projects and Capstones

Problem: Numerous recent studies have emerged detailing the benefits of horticultural therapy on mental health and wellness. Despite this, substance use disorder treatment facilities rarely include an outdoor component in their programming. The project seeks to examine the advantages of incorporating therapeutic gardening as a complementary part of addiction treatment.

Context: The microsystem where the study was conducted was at a 32-bed residential substance abuse treatment facility for adult men who have previously been involved in the criminal justice system. The treatment approach employed at the facility aligns with the Integrated Dual Disorder Treatment (IDDT) curriculum, which emphasizes mental health-informed …

Cover Crop Application On Dredged Sediments Increases Corn Yield Through Microorganism-Associated Enzyme-Driven Nutrient Mineralization, Ashley N. Julian, Louise M. Stevenson, Megan A. Rúa

Biological Sciences Faculty Publications

Background & Aims

Common strategies to mitigate soil degradation of agricultural soils include cover crop application and soil amendment addition. Applying dredged sediments as a soil amendment is gaining popularity since they often provide benefits other amendments lack; however, their use with cover crops is largely unexplored. To understand how cover crop use changes the restorative properties of dredged sediments, we assessed soil physical and chemical properties, enzymatic activities, and corn yield for plots of dredged sediments with and without a cover crop.

Methods

We assessed soil texture, bulk density, water content, pH, nitrogen, phosphorus, cation exchange capacity, calcium, magnesium, …

Tech Time

DePaul Magazine

DePaul is embracing tech more than ever, incorporating innovative devices and approaches into education in all corners of the university. Here are seven ways DePaul provides hands-on experiences with cutting-edge tools that position students and faculty in the forefront of their industries and disciplines.

School-Based Development And Implementation Of Adolescent Mental Health Educational Toolkits, Chantel M. Kilford Ms

Doctor of Nursing Practice (DNP) Projects

After the onset of the COVID pandemic, there were significant increases of adolescents with anxiety, behavioral and conduct problems. These disorders have devasting individual, social, and economic ramifications and school-based staff play a key role in identification, assessment, and treatment. Evidence suggested that healthcare providers, school counselors and teachers were not confident or knowledgeable about adolescent mental health. The purpose of the change in practice project was to increase knowledge and confidence among school-based healthcare providers, school counselors and teachers by providing an adolescent mental health tool kit. The toolkit focused on disruptive behavior and other prevalent mental health disorders …

How Sensory Exploration Using Expressive Arts Provides A Cohesive Experience For Children With Multiple Diagnoses, Chanelle Goguen

Expressive Therapies Capstone Theses

This thesis looks at the potential benefits and cohesive experience of sensory exploration for children with multiple diagnoses through a trauma informed lens. The researcher was inspired by Prendiville’s (2021) idea of how interactive sensory exploration and art making can help foster and develop reciprocal communication and socio-affective relationships influenced the researcher to design a method that would be used to collect data about potential similar findings. In the method, the interaction of the sensory-specific art mediums were reflected through the expressive therapies continuum (ETC) framework. The research of this thesis acknowledges and explores how trauma and adverse childhood experiences …

Historic Preservation: Launched From Grand Central Terminal, But Derailing, Kraz Greinetz

Duke Journal of Constitutional Law & Public Policy Sidebar

In Penn Central Transportation Co. v. City of New York, the Supreme Court authorized the practice of historic preservation. Ruling that when a city designates a building as "historic" and therefore restricting its development, it is not a "taking" of private property that requires just compensation under the Fifth Amendment. Since that time, historic preservation has proliferated in America's cities. But it's time for another look. Since Penn Central was decided, the facts and law of property regulation in the United States have changed. And the decision, which was wrong from an originalist perspective when it was decided, has …

Enhanced Throughput Of Aligned Polyacrylonitrile Nanofiber Manufacturing Via High-Speed Centrifugal Spinning, Jason Glen Ippolito

Theses and Dissertations

Centrifugal spinning is noteworthy due to its high fiber throughput rate compared to other nanofiber manufacturing platforms. It is capable of producing fibers in the nanoscale diameter range from a multitude of polymers, such as polyacrylonitrile (PAN). With a traditional centrifugal spinner, fiber can be rapidly spun and collected on static posts. However, the use of static posts inevitably forms a dense ring of fiber after a short period of time, and this fiber build up can halt the spinning process. In this work, the factors that influence the throughput and scalability of highly aligned centrifugally spun PAN fibers are …

The Intolerance Of Uncertainty: Transdiagnostic Connections Across Schizophrenia And Mood Spectrums, Obsessive Beliefs, And Physical Health, Sharanjit D. Pujji

Theses and Dissertations

The ways in which we classify mental health symptoms are closely tied to etiological understandings and interventions. While prominent diagnostic systems are categorical in nature, dimensional and transdiagnostic conceptualizations may provide increased precision and specificity that are more representative of “real-world” symptom presentations. The intolerance of uncertainty (IOU), an aversive state formed in reaction to the fear of the unknown, may have transdiagnostic value across mental and physical health. The current study sought to examine dimensionality across traditionally distinct symptoms and the transdiagnostic role of IOU across physical and mental health through the lens of the schizophrenia spectrum with an …

Unsorted Significance: Examining Potential Pathways To Extreme Political Beliefs And Communities On Reddit, Marcus Mann, Diana Zulli, Jeremy Foote, Emily Ku, Emily Primm

Purdue University Libraries Open Access Publishing Fund

Violent political extremists often point to online communities as motivating their behavior. However, researchers studying online exposure to extremism through structural mechanisms such as algorithms have not found strong evidence of their influence. At the same time, models of offline radicalization processes emphasize the importance of personal motivations, such as desire for significance and community, but do not fully account for online contexts. The authors integrate these approaches, which are both interested in worsening political extremism, asking, (1) What are the pathways to extreme content and communities online? and (2) What are the perceptions of extremism in online communities? Through …

Therapeutic Gardening For Addiction Recovery, Hayley Milleson

Master's Projects and Capstones

The following study examines the potential benefits of implementing therapeutic gardening and outdoor activities as a supplemental resource for adult males with a history of substance abuse issues who have been affected by the criminal justice system and are seeking sobriety while in a residential treatment program. The goal is to investigate how therapeutic gardening can add to traditional addiction treatment methods. Through a review of current evidence-based practice, this study focuses on how alternative interventions such as therapeutic gardening and outdoor activity can improve overall mental health and well-being, promote a sense of community, improve social connections, alleviate stress …

Predicting Alcohol-Related Memory Problems In Older Adults: A Machine Learning Study With Multi-Domain Features, Chella Kamarajan, Andrey P Anokhin, Sarah Hartz, Laura J Bierut, Vivia V Mccutcheon, Kathleen K Bucholz, Et Al.

2020-Current year OA Pubs

Memory problems are common among older adults with a history of alcohol use disorder (AUD). Employing a machine learning framework, the current study investigates the use of multi-domain features to classify individuals with and without alcohol-induced memory problems. A group of 94 individuals (ages 50-81 years) with alcohol-induced memory problems (the memory group) were compared with a matched control group who did not have memory problems. The random forests model identified specific features from each domain that contributed to the classification of the memory group vs. the control group (AUC = 88.29%). Specifically, individuals from the memory group manifested a …

A Standard Protocol To Report Discrete Stage-Structured Demographic Information, Samuel J. L. Gascoigne, Simon Rolph, Daisy Sankey, Nagalakshmi Nidadavolu, Adrian S. Stell Pičman, Christina M. Hernández, Matthew E. R. Philpott, Aiyla Salam, Connor Bernard, Erola Fenollosa, Young Jun Lee, Jessica Mclean, Shathuki Hetti Achchige Perera, Oliver G. Spacey, Maja Kajin, Anna C. Vinton, C. Ruth Archer, Jean H. Burns, Danielle L. Buss, Hal Caswell, Judy P. Che-Castaldo, Dylan Z. Childs, Pol Capdevila, Aldo Compagnoni, Elizabeth Crone, Thomas H. G. Ezard, Dave Hodgson, Tiffany M. Knight, Owen R. Jones, Eelke Jongejans, Jenni Mcdonald, Brigitte Tenhumberg, Chelsea C. Thomas, Andrew J. Tyre, Satu Ramula, Iain Stott, Raymond L. Tremblay, Phil Wilson, James James Vaupel, Roberto Salguero-Gómez

School of Biological Sciences: Faculty Publications

1. Stage-based demographic methods, such as matrix population models (MPMs), are powerful tools used to address a broad range of fundamental questions in ecology, evolutionary biology and conservation science. Accordingly, MPMs now exist for over 3000 species worldwide. These data are being digitised as an ongoing process and periodically released into two large open-access online repositories: the COMPADRE Plant Matrix Database and the COMADRE Animal Matrix Database. During the last decade, data archiving and curation of COMPADRE and COMADRE, and subsequent comparative research, have revealed pronounced variation in how MPMs are parameterized and reported.

2. Here, we summarise current issues related to …

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Louisiana State University Health Sciences Center - 2023 - 149th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 149th Commencement of LSU Health Sciences Center - New Orleans held May 18, 2023.

Full Issue: Spring 2023

DePaul Magazine

In the spring 2023 issue of DePaul Magazine, DePaul celebrates its 125th year and the university looks ahead to designing its future. With students and alumni who make a difference in their local and national communities, DePaul seeks to become the national model for higher education. We look at innovative programs at DePaul, including initiatives across the university that use emerging technology and an esports program that fosters inclusiveness and collaboration.

Depaul Digest

DePaul Magazine

Marquee - The Sound of Silents: Thomas Miller sets the scene with an original score to the sci-fi film "Metropolis"; Ask the Expert: Cryptocurrency expert Lamont Black, associate professor of finance in DePaul's Driehaus College of Business, explains the basics of crypto; Around Campus: news briefs from each of DePaul's 10 colleges and schools including College of Law litigation lab, prior learning assessment program, Bachelor of Science in Nursing, executive education certificate programs, preparing future teachers, Student Urban Research Corps, A Wrinkle in Time, Community Music Division Performathon, CS+ degrees and communication faculty fellow; Memoranda: The Finish Line Fund, nationwide …

Cxcl8/Cxcr2 Signaling Mediates Bone Marrow Fibrosis And Is A Therapeutic Target In Myelofibrosis, Andrew J Dunbar, Dongjoo Kim, Min Lu, Mirko Farina, Robert L Bowman, Julie L Yang, Young Park, Abdul Karzai, Wenbin Xiao, Zach Zaroogian, Kavi O'Connor, Shoron Mowla, Francesca Gobbo, Paola Verachi, Fabrizio Martelli, Giuseppe Sarli, Lijuan Xia, Nada Elmansy, Maria Kleppe, Zhuo Chen, Yang Xiao, Erin Mcgovern, Jenna Snyder, Aishwarya Krishnan, Corrine Hill, Keith Cordner, Anouar Zouak, Mohamed E Salama, Jayden Yohai, Eric Tucker, Jonathan Chen, Jing Zhou, Timothy Mcconnell, Anna R Migliaccio, Richard Koche, Raajit Rampal, Rong Fan, Ross L Levine, Ronald Hoffman

Faculty, Staff and Student Publications

Proinflammatory signaling is a hallmark feature of human cancer, including in myeloproliferative neoplasms (MPNs), most notably myelofibrosis (MF). Dysregulated inflammatory signaling contributes to fibrotic progression in MF; however, the individual cytokine mediators elicited by malignant MPN cells to promote collagen-producing fibrosis and disease evolution are yet to be fully elucidated. Previously, we identified a critical role for combined constitutive JAK/STAT and aberrant NF-κB proinflammatory signaling in MF development. Using single-cell transcriptional and cytokine-secretion studies of primary cells from patients with MF and the human MPLW515L (hMPLW515L) murine model of MF, we extend our previous work and delineate the role of …

Pou4f1-Tbr1 Transcriptional Cascade Controls The Formation Of Jam2-Expressing Retinal Ganglion Cells, Takae Kiyama, Halit Y Altay, Tudor C Badea, Chai-An Mao

Faculty, Staff and Student Publications

More than 40 retinal ganglion cell (RGC) subtypes have been categorized in mouse based on their morphologies, functions, and molecular features. Among these diverse subtypes, orientation-selective Jam2-expressing RGCs (J-RGCs) has two unique morphologic characteristics: the ventral-facing dendritic arbor and the OFF-sublaminae stratified terminal dendrites in the inner plexiform layer. Previously, we have discovered that T-box transcription factor T-brain 1 (Tbr1) is expressed in J-RGCs. We further found that Tbr1 is essential for the expression of Jam2, and Tbr1 regulates the formation and the dendritic morphogenesis of J-RGCs. However, Tbr1 begins to express in terminally differentiated RGCs around …

African American Women Make Meaning Of Historical Trauma, Deidre A. Miller

Doctoral Dissertations

ABSTRACT

Historical trauma may be a fairly new concept for some providers; therefore, this research offers another clinical lens through which providers can view the presenting problem(s) of their African American female patients. This qualitative study used descriptive methodology to examine the range of African American women’s lived experiences connected to historical trauma with two interlocking systems of oppression: race and gender. Two themes and six subthemes were developed from the data collected: Theme A: Prevalence of Racist Experiences Throughout Their Lifespans; and Theme B: Responses to Racism (e.g., Emotions & Coping Mechanisms).

This study gives clinicians insight into the …

A Neutrosophic Framework For Assessment Of Distributed Circular Water To Give Neighborhoods Analysis To Prepare For Unexpected Stressor Events, Mohamed Abouhawwash, Mohammed Jameel, Sameh S. Askar

Neutrosophic Systems with Applications

The global water issue is caused by a number of factors, including extreme weather, population increase, and industrial activity. One of the reasons we're running out of water as a planet is because of the outdated take-make-use-throw-away linear paradigm of handling water. It has been suggested that the circular economy may help alleviate water shortages by inspiring a fundamental change in municipal water infrastructure. Reduced consumption, recovered natural resources, and minimal waste are the three pillars of a circular water supply. A dispersed water supply is more adaptable and robust than a centralized one because it gives communities more time …

Chemoattractant Distribution In Complex Geometry Impacts The Trajectory Of Clustered Cell Migration, Naghmeh Akhavan

Biology and Medicine Through Mathematics Conference

No abstract provided.

Bura Ura, Kendu Waiyo (Rain Falls, Water Rises): The Tyranny Of Water Insecurity And An Agenda For Abolition In Kodi (Sumba Island, Indonesia), Cynthia Twyford Fowler

Faculty Scholarship

This article explores the dynamic links between transformations in freshwater ecosystems and social changes in the Kodi region of Sumba (Indonesia). Insights into the politics surrounding changing hydrosocial systems are generated by using a feminist anthropology approach together with critical development studies and intersectionality theory. In aligning with fellow feminists whose advocacy sometimes takes the form of scholarship, I lay out a five-prong strategy for collecting empirical evidence from persons who are vulnerable when hydrological systems change and offer eight principles for future development interventions. The argument related to the five-prong toolkit is that by conducting intensive, extensive, opportunistic, and …