Digital Commons Network^™

Of Houses And Raiments – Philosophical Aspects Of Corporality In Arda, Thomas Fornet Ponse

Journal of Tolkien Research

It is well known that theological and philosophical considerations became increasingly important for J.R.R. Tolkien. The publication of The Nature of Middle-earth is a proof of that since this collection of both published and unpublished writings by J.R.R. Tolkien deals with natural aspects, such as the hair or beards of the inhabitants of Arda, as well as metaphysical topics like free will or reincarnation. This publication makes it possible to analyze the interdependence of Tolkien’s thoughts on the operation of time and ageing with the relationship of mind/spirit and body, and thus both the inner consistency and coherence of his …

Platonism’S Influence On The Hermeneutic Of Augustine: Exploring The Philosophical Roots Of Augustine’S Interpretive Approach, Kent T. Maitland

Liberty Theological Review

This paper contends that Augustine was a significant contributor to the “Spiritual Vision Model” of the Christian conception of heaven described by Craig Blaising. This model is premised on the Platonic understanding of perfection in which the soul unites with the Good, and heaven is primarily a cognitive state in which the individual possesses perfect spiritual knowledge. This model also provides a rational basis for favoring a figurative or spiritualized interpretation of Scripture over its literal meaning. Augustine’s early life and conversion reflects a commitment to the SVM’s Platonic ideals, as demonstrated in his deference to Cicero, his journey into …

The Voice Of The Singers At The Watering Places: Victory Songs As A Celebration Of Recreation, J Christian Doling

Liberty Theological Review

Victory songs were sung by women to welcome home the men from victorious war. Some prophetic variants appeared from these songs that had a theology of salvation and recreation. Beside the message of the songs, the context of these songs also show that recreation was a major theme of these musical compositions. Warfare was about the expansion of creation from an ordered center in the Ancient Near East. For Israel the center was Yahweh’s presence with Israel being a new Eden. Recreation of the chaotic lands around Israel required that Israel went to war to subdue those lands and people. …

American Indian Residential Boarding Schools: Historical Trauma And The Role Of Government, Churches, And Tribes In Healing Indigenous Communities, Briana Slaubaugh

Liberty Theological Review

Throughout the 19^th and 20^th centuries, Native Americans and Indigenous tribes in North America faced systematic destruction of their cultures, genocide, and extreme abuse. With wars against Native Americans, forced relocation from their historic lands, and mandatory residential boarding schools where Indigenous children were forcibly separated from their parents, the social fabric of Native American communities was destroyed. These travesties were government sanctioned and enacted by churches. The American Indian Residential Schools serve as the most recent and egregious factories of abuse. The policies and actions enforced against Native Americans left a generation plagued by abuse leaving a …

Human Ecology, 1990, V19 N2, Advocate Aurora Health

Historical Documents - Combined

Lutheran General Hospital, Park Ridge, IL: Biannual magazine produced for the Friends of the Affiliated Corporations of Lutheran General Health Care System. This issue has features on hospital profits, diabetes, alcoholism, living wills and advanced directives, in vitro fertilization, and an update from the annual fundraising gala.

Human Ecology, 1991, V20 N1, Advocate Aurora Health

Historical Documents - Combined

Lutheran General Hospital, Park Ridge, IL: Biannual magazine produced for the Friends of the Affiliated Corporations of Lutheran General Health Care System. This issue has features on adult day health services, addiction, Fragile X Syndrome, euthanasia, weight loss, and a doctor with hearing loss. It also features the annual donor list.

Human Ecology, 1992, V21 N1, Advocate Aurora Health

Historical Documents - Combined

Lutheran General Hospital, Park Ridge, IL: Biannual magazine produced for the Friends of the Affiliated Corporations of Lutheran General Health Care System. This issue has features on anger management, 'strong medicine', arthritis, and aging.

Biological Case Against Downlisting The Whooping Crane And For Improving Implementation Under The Endangered Species Act, Andrew J. Caven, Hillary L. Thompson, David M. Baasch, Barry K. Hartup, Amanda M. Hegg, Stephanie M. Schmidt, Irvin Louque, Craig R. Allen, Carter G. Crouch, Craig A. Davis, Joel G. Jorgensen, Jane E. Austin, Bethany L. Ostrom, Richard D. Beilfuss, George W. Archibald, Anne E. Lacy

School of Natural Resources: Faculty Publications

The Whooping Crane (Grus americana; WHCR) is a large, long-lived bird endemic to North America. The remnant population migrates between Aransas National Wildlife Refuge, USA, and Wood Buffalo National Park, Canada (AWBP), and has recovered from a nadir of 15-16 birds in 1941 to ~540 birds in 2022. Two ongoing reintroduction efforts in Louisiana and the Eastern Flyway together total ~150 birds. Evidence indicates the U.S. Fish and Wildlife Service (USFWS) is strongly considering downlisting the species from an endangered to a threatened status under the Endangered Species Act (ESA). We examined the current status of the WHCR through the …

Benerd Review - June 2023, Benerd College

Benerd Review

No abstract provided.

Stability-Based Generalization Analysis For Mixtures Of Pointwise And Pairwise Learning, Jiahuan Wang, Jun Chen, Hong Chen, Bin Gu, Weifu Li, Xin Tang

Machine Learning Faculty Publications

Recently, some mixture algorithms of pointwise and pairwise learning (PPL) have been formulated by employing the hybrid error metric of “pointwise loss + pairwise loss” and have shown empirical effectiveness on feature selection, ranking and recommendation tasks. However, to the best of our knowledge, the learning theory foundation of PPL has not been touched in the existing works. In this paper, we try to fill this theoretical gap by investigating the generalization properties of PPL. After extending the definitions of algorithmic stability to the PPL setting, we establish the high-probability generalization bounds for uniformly stable PPL algorithms. Moreover, explicit convergence …

Greyfriars Bobby, Kathleen Rowan

Tales of WellBeing

Bobby, a small terrier in Edinburgh, is another example of canine post mortem devotion to a human companion.

A Comprehensive Assay Of Social Motivation Reveals Sex-Specific Roles Of Autism-Associated Genes And Oxytocin, Susan E Maloney, Simona Sarafinovska, Claire Weichselbaum, Katherine B Mccullough, Raylynn G Swift, Yating Liu, Joseph D Dougherty

2020-Current year OA Pubs

Social motivation is critical to the development of typical social functioning. Social motivation, specifically one or more of its components (e.g., social reward seeking or social orienting), could be relevant for understanding phenotypes related to autism. We developed a social operant conditioning task to quantify effort to access a social partner and concurrent social orienting in mice. We established that mice will work for access to a social partner, identified sex differences, and observed high test-retest reliability. We then benchmarked the method with two test-case manipulations.

Integrative Genetic Approach Facilitates Precision Strategies For Acute Myocardial Infarction, Muzamil Khawaja, Rehma Siddiqui, Salim S Virani, Christopher I Amos, Dhrubajyoti Bandyopadhyay, Hafeez Ul Hassan Virk, Mahboob Alam, Hani Jneid, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Acute myocardial infarction remains a significant cause of mortality worldwide and its burden continues to grow. Its pathophysiology is known to be complex and multifactorial, with several acquired and inherited risk factors. As advances in technology and medical therapy continue, there is now increasing recognition of the role that genetics play in the development and management of myocardial infarction. The genetic determinants of acute coronary syndrome are still vastly understudied, but the advent of whole-genome scanning and genome-wide association studies has significantly expanded the current understanding of genetics and simultaneously fostered hope that genetic profiling and gene-guided treatments could substantially …

Bend And Not Break: Examining Hispanic Engineering Student's Academic Challenges During Covid-19, Eleazar Marquez, Samuel Garcia

Mechanical Engineering Faculty Publications

Student success in higher education remains an area of interest, particularly for underrepresented minorities. Studies reveal that while Latino college enrollment has increased, retention rates continue to be an ongoing struggle. Several factors that attribute to such low rates include academic self-concept, family support, cognitive mapping, managing resources, background characteristics, and separation and maintenance of family ties. In the wake of COVID-19, most institutions responded by terminating in-person instruction, mandating to seek off-campus housing, and shifting to a fully remote context. As such, students were unable to utilize campus resources and engage in established educational campus practices. In this research …

Comparative Toxicity Assessment Of Glyphosate And Two Commercial Formulations In The Planarian Dugesia Japonica, S. Grace Fuselier , '25, Danielle Ireland, Nicholas Fu , '25, Christina Rabeler, Eva-Maria S. Collins

Biology Faculty Works

Introduction: Glyphosate is a widely used, non-selective herbicide. Glyphosate and glyphosate-based herbicides (GBHs) are considered safe for non-target organisms and environmentally benign at currently allowed environmental exposure levels. However, their increased use in recent years has triggered questions about possible adverse outcomes due to low dose chronic exposure in animals and humans. While the toxicity of GBHs has primarily been attributed to glyphosate, other largely unstudied components of GBHs may be inherently toxic or could act synergistically with glyphosate. Thus, comparative studies of glyphosate and GBHs are needed to parse out their respective toxicity. Methods: We performed such a comparative …

Effect Of Fibrinolytic Therapy On St-Elevation Myocardial Infarction Clinical Outcomes During The Covid-19 Pandemic: A Systematic Review And Meta-Analysis, Anwar Khedr, Hussam Al Hennawi, Muhammed Khuzzaim Khan, Mostafa Elbanna, Abbas B. Jama, Ekaterina Proskuriakova, Hisham Mushtaq, Mikael Mir, Sydney Boike, Ibtisam Rauf, Aalaa Eissa, Meritxell Urtecho, Thoyaja Koritala, Nitesh Jain, Lokesh Goyal, Salim Surani, Syed A Khan

Abington Jefferson Health Papers

BACKGROUND: ST-elevation myocardial infarction (STEMI) is the result of transmural ischemia of the myocardium and is associated with a high mortality rate. Primary percutaneous coronary intervention (PPCI) is the recommended first-line treatment strategy for patients with STEMI. The timely delivery of PPCI became extremely challenging for STEMI patients during the coronavirus disease 2019 (COVID-19) pandemic, leading to a projected steep rise in mortality. These delays were overcome by the shift from first-line therapy and the development of modern fibrinolytic-based reperfusion. It is unclear whether fibrinolytic-based reperfusion therapy is effective in improving STEMI endpoints.

AIM: To determine the incidence of fibrinolytic …

The Exploitation Of Toxic Fish From The Terminal Pleistocene In Maritime Southeast Asia: A Case Study From The Mindoro Archaeological Sites, Philippines, Clara Boulanger, Alfred Pawlik, Sue O'Connor, Anne-Marie Sémah, Marian C. Reyes, Thomas Ingicco

Sociology & Anthropology Department Faculty Publications

Representatives of the Diodontidae family (porcupinefish) are known to have been fished by prehistoric Indo-Pacific populations; however, the antiquity of the use of this family is thus far unknown. We report here on the presence of Diodontidae in the archaeological sites of Bubog I, II, and Bilat in Mindoro, Philippines, dating back to c. 13,000 BP (Before Present). This evidence demonstrates the early exploitation by islanders of poisonous fish. Every part of porcupinefish can be toxic, but the toxicity is mostly concentrated in some organs, while other parts are edible. The continuous presence of Diodontidae remains throughout the stratigraphic record …

Green Lighting The Altruistic Influencer, Savanna Rebecca Bagley

Theses and Dissertations

This paper comprehensively examines a new type of social media influencer characterized by altruistic tendencies. Utilizing the popular YouTube channel Vlogbrothers as the case study text for a constant comparative analysis, this research explores how the strategies altruistic influencers use to mobilize their community for good, the characteristics of the altruistic influencers, and how altruistic influencers create community. Through an in-depth analysis of 30 Vlogbrothers videos, the themes of education, community, and shared humanity emerged. Education, shared values, and calls to action are discussed as essential for mobilizing communities in charitable endeavors. Authenticity, quality, accessibility, and solutions-focused action were found …

Evaluation Of The Orally Bioavailable 4-Phenylbutyrate-Tethered Trichostatin A Analogue Ar42 In Models Of Spinal Muscular Atrophy, Casey J. Lumpkin, Ashlee W. Harris, Andrew J. Connell, Ryan W. Kirk, Joshua A. Whiting, Luciano Saieva, Livio Pellizzoni, Arthur H.M. Burghes, Matthew E.R. Butchbach

Department of Pediatrics Faculty Papers

Proximal spinal muscular atrophy (SMA) is a leading genetic cause for infant death in the world and results from the selective loss of motor neurons in the spinal cord. SMA is a consequence of low levels of SMN protein and small molecules that can increase SMN expression are of considerable interest as potential therapeutics. Previous studies have shown that both 4-phenylbutyrate (4PBA) and trichostatin A (TSA) increase SMN expression in dermal fibroblasts derived from SMA patients. AR42 is a 4PBA-tethered TSA derivative that is a very potent histone deacetylase inhibitor. SMA patient fibroblasts were treated with either AR42, AR19 (a …

The Allegory Of United States Settlers V. Native Americans In Wes Craven's The Hills Haves Eyes (1977), Blue Van Alst

University Honors Theses

The year 1977 saw the release of Wes Craven’s second major production, The Hills Have Eyes. A film that sits within a filmic library of Craven that works to use the horror genre to reflect on and critique the American society that he lived in. The Hills Have Eyes employs the stereotypes that the films of John Ford helped to solidify in U.S. society. He does this in order to explore the tense historical relationships between Indigenous and United States settlers during the time of westward expansion. Using the white middle class Carter family to serve as settlers, and …

Energetic Costs Of Testosterone In Two Subsistence Populations, Benjamin C. Trumble, Herman Pontzer, Jonathan Stieglitz, Daniel K. Cummings, Brian Wood, Melissa Emery Thompson, David Raichlen, Bret Beheim, Gandhi Yetish, Hillard Kaplan, Michael Gurven

ESI Publications

Objective

Testosterone plays a role in mediating energetic trade-offs between growth, maintenance, and reproduction. Investments in a high testosterone phenotype trade-off against other functions, particularly survival-enhancing immune function and cellular repair; thus only individuals in good condition can maintain both a high testosterone phenotype and somatic maintenance. While these effects are observed in experimental manipulations, they are difficult to demonstrate in free-living animals, particularly in humans. We hypothesize that individuals with higher testosterone will have higher energetic expenditures than those with lower testosterone.

Methods

Total energetic expenditure (TEE) was quantified using doubly labeled water in n = 40 Tsimane forager-horticulturalists …

Acetate-Encapsulated Linolenic Acid Liposomes Reduce Sars-Cov-2 And Rsv Infection, Andrew R. Mcgill

USF Tampa Graduate Theses and Dissertations

Coronavirus disease-19 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is an ongoing pandemic-endemic. In the United States, it remains the third leading cause of death in 2022. SARS-CoV-2, an RNA virus, has a genome prone to rapid mutation, generating variant species capable of resisting therapies and vaccination efforts. However, it has been estimated that more than 40% of SARS-CoV-2 infections may be asymptomatic, which calls into question any biological differences between the asymptomatic and afflicted groups. Additionally, Respiratory Syncytial Virus (RSV) is the most significant cause of bronchiolitis and asthma in neonates, with an increasing burden on the …

Detrimental Effects Of Pcsk9 Loss-Of-Function In The Pediatric Host Response To Sepsis Are Mediated Through Independent Influence On Angiopoietin-1., Mihir R. Atreya, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Matthew N. Alder, Patrick Lahni, Scarlett Ripberger, Adesuwa Ekunwe, Kyle R. Campbell, Keith R. Walley, Stephen W. Standage

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Sepsis is associated with significant mortality. Yet, there are no efficacious therapies beyond antibiotics. PCSK9 loss-of-function (LOF) and inhibition, through enhanced low-density lipoprotein receptor (LDLR) mediated endotoxin clearance, holds promise as a potential therapeutic approach among adults. In contrast, we have previously demonstrated higher mortality in the juvenile host. Given the potential pleiotropic effects of PCSK9 on the endothelium, beyond canonical effects on serum lipoproteins, both of which may influence sepsis outcomes, we sought to test the influence of PCSK9 LOF genotype on endothelial dysfunction.

METHODS: Secondary analyses of a prospective observational cohort of pediatric septic shock. Genetic variants …

Effect Of Ishophloroglucin A Isolated From Ishige Okamurae On In Vitro Osteoclastogenesis And Osteoblastogenesis, Su-Hyeon Cho, Hyun-Soo Kim, Hye-Yeon Jung, Jae-Il Park, You-Jee Jang, Juhee Ahn, Kil-Nam Kim

Faculty, Staff and Student Publications

The balance between bone-resorbing osteoclasts and bone-forming osteoblasts is essential for the bone remodeling process. This study aimed to investigate the effect of Ishophloroglucin A (IPA) isolated from Ishige okamurae on the function of osteoclasts and osteoblasts in vitro. First, we demonstrated the effect of IPA on osteoclastogenesis in receptor activator of nuclear factor κB ligand (RANKL)-induced RAW 264.7 cells. IPA inhibited the tartrate-resistant acid phosphatase (TRAP) activity and osteoclast differentiation in RANKL-induced RAW 264.7 cells. Moreover, it inhibited the RANKL-induced osteoclast-related factors, such as TRAP, matrix metalloproteinase-9 (MMP-9), and calcitonin receptor (CTR), and transcription factors, such as nuclear factor …

Learning In Transition: Developing And Employing Pedagogical Supports To Enhance Student Learning In Engineering Education, Eleazar Marquez, Samuel Garcia

Mechanical Engineering Faculty Publications

Scholarly research indicates that classroom environment and conditions influence the degree of student learning, levels of engagement, and overall success in engineering education. In the wake of COVID-19, educational institutions transitioned to fully online delivery that disrupted traditional and effective channels of communication enacted in classroom contexts. For a substantial number of faculty members, this rapid transition to a fully remote instructional context marked the start a novel style of teaching and learning environment, a grand departure from the traditional, direct face-to-face setting. Such rapid and disruptive change required creative solutions to routinized instructional practices and compelling faculty to adjust …

Transcriptome- And Proteome-Wide Association Studies Nominate Determinants Of Kidney Function And Damage, Pascal Schlosser, Jingning Zhang, Hongbo Liu, Aditya L Surapaneni, Eugene P Rhee, Dan E Arking, Bing Yu, Eric Boerwinkle, Paul A Welling, Nilanjan Chatterjee, Katalin Susztak, Josef Coresh, Morgan E Grams

Faculty, Staff and Student Publications

BACKGROUND: The pathophysiological causes of kidney disease are not fully understood. Here we show that the integration of genome-wide genetic, transcriptomic, and proteomic association studies can nominate causal determinants of kidney function and damage.

RESULTS: Through transcriptome-wide association studies (TWAS) in kidney cortex, kidney tubule, liver, and whole blood and proteome-wide association studies (PWAS) in plasma, we assess for effects of 12,893 genes and 1342 proteins on kidney filtration (glomerular filtration rate (GFR) estimated by creatinine; GFR estimated by cystatin C; and blood urea nitrogen) and kidney damage (albuminuria). We find 1561 associations distributed among 260 genomic regions that are …

Molecular And Morphological Confirmation Of Isometrus Maculatus (Degeer, 1778) (Scorpiones: Buthidae) From Northeast India And East Asia, Shubhankar Deshpande, Mihir Joshi, Kazusa Kawai, Arnab Deb, Jeng-Di Lee, Deshabhushan Bastawade, Gaurang Gowande, Shauri Sulakhe

Euscorpius

We present molecular data on Isometrus maculatus (DeGeer, 1778) for the first time from India, Japan, and Taiwan based on the COI gene and justify the cosmopolitan nature of this species. We also address the first population of I. maculatus found in Teliamura, Tripura, India and give its detailed description and comparison with the rest of the Isometrus species from India. Furthermore, we discuss the justification for considering Sri Lanka as the true home of I. maculatus.

Using Culturally Significant Birds To Guide The Timing Of Prescribed Fires In The Klamath Siskiyou Bioregion, Linda L. Long, Frank L. Lake, Jaime L. Stephens, John D. Alexander, C. John Ralph, Jared D. Wolfe

Michigan Tech Publications, Part 1

Historically, wildfire and tribal burning practices played important roles in shaping ecosystems throughout the Klamath Siskiyou Bioregion of northern California and southern Oregon. Over the past several decades, there has been increased interest in the application of fire for forest management through the implementation of prescribed fires within habitats that are used by a diversity of migrant and resident land birds. While many bird species may benefit from habitat enhancements associated with wildfires, cultural burning, and prescribed fire, individuals may face direct or indirect harm. In this study, we analyzed the timing of breeding and molting in 11 species of …

Systemic Review Of Clot Retraction Modulators, Alaina Guilbeau, Rinku Majumder

School of Graduate Studies Faculty Publications

Through a process termed clot retraction, platelets cause thrombi to shrink and become more stable. After platelets are activated via inside-out signaling, glycoprotein αIIbβIII binds to fibrinogen and initiates a cascade of intracellular signaling that ends in actin remodeling, which causes the platelet to change its shape. Clot retraction is also important for wound healing. Although the detailed molecular biology of clot retraction is only partially understood, various substances and physiological conditions modulate clot retraction. In this review, we describe some of the current literature pertaining to clot retraction modulators. In addition, we discuss compounds from Cudrania trucuspidata, Arctium lappa, …

Design And Application Of The 3d Model Interfaces Of The Integrated Intelligent Mine Control Platform, Zhang Jing

Coal Geology & Exploration

The production safety control platform for mines is used to present information on the centralized scheduling, real-time monitoring, risk prevention and control, operation and maintenance detection, and decision analysis of various equipment and automated, intelligent production systems for tunneling, mining, machinery, transportation, and ventilation during coal mine production. Accordingly, the interface design of the integrated intelligent mine control platform is particularly important for user experience. However, the current integrated automation systems for mines adopt monochrome configuration engineering plans and display a single interface effect of display and operation. By introducing the industrial design concepts and employing the 3D model interface …