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Articles 76051 - 76080 of 743058

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Graphical Method For Solving Neutrosophical Nonlinear Programming Models, Maissam Jdid, Florentin Smarandache Sep 2023

Graphical Method For Solving Neutrosophical Nonlinear Programming Models, Maissam Jdid, Florentin Smarandache

Neutrosophic Systems with Applications

An important method for finding the optimal solution for linear and nonlinear models is the graphical method, which is used if the linear or nonlinear mathematical model contains one, two, or three variables. The models that contain only two variables are among the most models for which the optimal solution has been obtained graphically, whether these models are linear or non-linear in references and research that are concerned with the science of operations research, when the data of the issue under study is classical data. In this research, we will present a study through, which we present the graphical method …

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A New Approach For The Statistical Convergence Over Non-Archimedean Fields In Neutrosophic Normed Spaces, Jeyaraman M., Iswariya S. Sep 2023

A New Approach For The Statistical Convergence Over Non-Archimedean Fields In Neutrosophic Normed Spaces, Jeyaraman M., Iswariya S.

Neutrosophic Systems with Applications

The goal of the research involves elaborating on the topics of statistical convergence, including statistical Cauchy sequences within non-Archimedean Neutrosophic normed spaces, as well as achieving specific useful conclusions. The present research shows how, within a non-Archimedean field, certain sections of statistically convergent sequences that could not be true often become true. Likewise, we created statistically complete and statistically continuous spaces for such regions that demonstrated certain essential facts. κ indicates a complete field of non-Archimedean and non-trivially valued research.

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Streetwalkers : Prostituées Et Philosophes, Sur Les Scènes Parisiennes De 1730 À 1830., Elodie Tantet Sep 2023

Streetwalkers : Prostituées Et Philosophes, Sur Les Scènes Parisiennes De 1730 À 1830., Elodie Tantet

Arts & Sciences Graduate Student Theses and Dissertations

Dans une approche socio-historique, cette thèse observe un phénomène social en France qui remonte à l'époque de la Révolution, à savoir les *streetwalkers*, qu'il s'agisse des femmes dans la rue ou des hommes qui les observent et les représentent. Une citation de Peaky Blinders - "Everyone’s a whore […], we just sell different part of ourselves" (#1.3, 2013) - fournit le point de départ de notre enquête sur le rôle de la marche dans la rue dans la littérature de la fin du XVIIIe et du début du XIXe siècle. Notre étude révèle que non seulement les prostituées et les …

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Beyond The Symptom: The Biology Of Fatigue, David M Raizen, Janet Mullington, Christelle Anaclet, Gerard Clarke, Hugo Critchley, Ronald Davis, Josh Fessel, Patrick M Fuller, Erin M Gibson, Mary Harrington, W Ian Lipkin, Elizabeth B Klerman, Nancy Klimas, Anthony L Komaroff, Walter Koroshetz, Lauren Krupp, Anna Kuppuswamy, Julie Lasselin, Laura D Lewis, Pierre J Magistretti, Heidi Y Matos, Christine Miaskowski, Andrew H Miller, Avindra Nath, Maiken Nedergaard, Mark R Opp, Marylyn D Ritchie, Dragana Rogulja, Asya Rolls, John D Salamone, Clifford Saper, Vicky Whittemore, Glenn Wylie, Jarred Younger, Phyllis C Zee, H Craig Heller Sep 2023

Beyond The Symptom: The Biology Of Fatigue, David M Raizen, Janet Mullington, Christelle Anaclet, Gerard Clarke, Hugo Critchley, Ronald Davis, Josh Fessel, Patrick M Fuller, Erin M Gibson, Mary Harrington, W Ian Lipkin, Elizabeth B Klerman, Nancy Klimas, Anthony L Komaroff, Walter Koroshetz, Lauren Krupp, Anna Kuppuswamy, Julie Lasselin, Laura D Lewis, Pierre J Magistretti, Heidi Y Matos, Christine Miaskowski, Andrew H Miller, Avindra Nath, Maiken Nedergaard, Mark R Opp, Marylyn D Ritchie, Dragana Rogulja, Asya Rolls, John D Salamone, Clifford Saper, Vicky Whittemore, Glenn Wylie, Jarred Younger, Phyllis C Zee, H Craig Heller

Faculty, Staff and Student Publications

A workshop titled "Beyond the Symptom: The Biology of Fatigue" was held virtually September 27-28, 2021. It was jointly organized by the Sleep Research Society and the Neurobiology of Fatigue Working Group of the NIH Blueprint Neuroscience Research Program. For access to the presentations and video recordings, see: https://neuroscienceblueprint.nih.gov/about/event/beyond-symptom-biology-fatigue. The goals of this workshop were to bring together clinicians and scientists who use a variety of research approaches to understand fatigue in multiple conditions and to identify key gaps in our understanding of the biology of fatigue. This workshop summary distills key issues discussed in this workshop and provides a …

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Modulation Of The Proteostasis Network Promotes Tumor Resistance To Oncogenic Kras Inhibitors, Xiangdong Lv, Xuan Lu, Jin Cao, Qin Luo, Yao Ding, Apar Pataer, Dong Han, Eric Malmberg, Doug W Chan, Xiaoran Wang, Sara R Savage, Sufeng Mao, Jingjing Yu, Fei Peng, Liang Yan, Huan Meng, Laure Maneix, Yumin Han, Yiwen Chen, Wantong Yao, Eric C Chang, Andre Catic, Xia Lin, George Miles, Pengxiang Huang, Zheng Sun, Bryan Burt, Huamin Wang, Jin Wang, Qizhi Cathy Yao, Bing Zhang, Jack A Roth, Bert W O'Malley, Matthew J Ellis, Mothaffar F Rimawi, Haoqiang Ying, Xi Chen Sep 2023

Modulation Of The Proteostasis Network Promotes Tumor Resistance To Oncogenic Kras Inhibitors, Xiangdong Lv, Xuan Lu, Jin Cao, Qin Luo, Yao Ding, Apar Pataer, Dong Han, Eric Malmberg, Doug W Chan, Xiaoran Wang, Sara R Savage, Sufeng Mao, Jingjing Yu, Fei Peng, Liang Yan, Huan Meng, Laure Maneix, Yumin Han, Yiwen Chen, Wantong Yao, Eric C Chang, Andre Catic, Xia Lin, George Miles, Pengxiang Huang, Zheng Sun, Bryan Burt, Huamin Wang, Jin Wang, Qizhi Cathy Yao, Bing Zhang, Jack A Roth, Bert W O'Malley, Matthew J Ellis, Mothaffar F Rimawi, Haoqiang Ying, Xi Chen

Faculty, Staff and Student Publications

Despite substantial advances in targeting mutant KRAS, tumor resistance to KRAS inhibitors (KRASi) remains a major barrier to progress. Here, we report proteostasis reprogramming as a key convergence point of multiple KRASi-resistance mechanisms. Inactivation of oncogenic KRAS down-regulated both the heat shock response and the inositol-requiring enzyme 1α (IRE1α) branch of the unfolded protein response, causing severe proteostasis disturbances. However, IRE1α was selectively reactivated in an ER stress-independent manner in acquired KRASi-resistant tumors, restoring proteostasis. Oncogenic KRAS promoted IRE1α protein stability through extracellular signal-regulated kinase (ERK)-dependent phosphorylation of IRE1α, leading to IRE1α disassociation from 3-hydroxy-3-methylglutaryl reductase degradation (HRD1) E3-ligase. In …

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Structures Of Ctcf-Dna Complexes Including All 11 Zinc Fingers, Jie Yang, John R Horton, Bin Liu, Victor G Corces, Robert M Blumenthal, Xiaodong Cheng Sep 2023

Structures Of Ctcf-Dna Complexes Including All 11 Zinc Fingers, Jie Yang, John R Horton, Bin Liu, Victor G Corces, Robert M Blumenthal, Xiaodong Cheng

Faculty, Staff and Student Publications

The CCCTC-binding factor (CTCF) binds tens of thousands of enhancers and promoters on mammalian chromosomes by means of its 11 tandem zinc finger (ZF) DNA-binding domain. In addition to the 12-15-bp CORE sequence, some of the CTCF binding sites contain 5' upstream and/or 3' downstream motifs. Here, we describe two structures for overlapping portions of human CTCF, respectively, including ZF1-ZF7 and ZF3-ZF11 in complex with DNA that incorporates the CORE sequence together with either 3' downstream or 5' upstream motifs. Like conventional tandem ZF array proteins, ZF1-ZF7 follow the right-handed twist of the DNA, with each finger occupying and recognizing …

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Hdac6 And Erk/Adam17 Regulate Vegf-Induced Notch Signaling In Lung Endothelial Cells., Sheng Xia, Heather Menden, Sherry M. Mabry, Venkatesh Sampath Sep 2023

Hdac6 And Erk/Adam17 Regulate Vegf-Induced Notch Signaling In Lung Endothelial Cells., Sheng Xia, Heather Menden, Sherry M. Mabry, Venkatesh Sampath

Manuscripts, Articles, Book Chapters and Other Papers

Angiogenesis plays a critical role in various physiological and pathological processes and is regulated by VEGF. Histone Deacetylase 6 (HDAC6) is a class IIB HDAC that regulates cytoplasmic signaling through deacetylation and is emerging as a target for modulating angiogenesis. We investigated the hypothesis that VEGF-induced endothelial cell (EC) NOTCH signaling is regulated by HDAC6 through acetylation of NOTCH intracellular cytoplasmic domain (NICD). In pulmonary endothelial cells (EC), VEGF-induced activation of the NICD transcriptional response was regulated by ERK1/2 and ADAM 17 and required DLL4. While HDAC6 inhibition induced the acetylation of NICD and stabilized NICD, it repressed NICD-SNW1 binding …

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Argininosuccinate Lyase Deficiency Causes Blood-Brain Barrier Disruption Via Nitric Oxide-Mediated Dysregulation Of Claudin Expression, Jill V Hunter, Robia G Pautler, Hannah P Thompson, Akihiko Urayama, Zixue Jin, Brendan Lee Sep 2023

Argininosuccinate Lyase Deficiency Causes Blood-Brain Barrier Disruption Via Nitric Oxide-Mediated Dysregulation Of Claudin Expression, Jill V Hunter, Robia G Pautler, Hannah P Thompson, Akihiko Urayama, Zixue Jin, Brendan Lee

Faculty, Staff and Student Publications

Nitric oxide (NO) is a critical signaling molecule that has been implicated in the pathogenesis of neurocognitive diseases. Both excessive and insufficient NO production have been linked to pathology. Previously, we have shown that argininosuccinate lyase deficiency (ASLD) is a novel model system to investigate cell-autonomous, nitric oxide synthase-dependent NO deficiency. Humans with ASLD are at increased risk for developing hyperammonemia due to a block in ureagenesis. However, natural history studies have shown that individuals with ASLD have multisystem disease including neurocognitive deficits that can be independent of ammonia. Here, using ASLD as a model of NO deficiency, we investigated …

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A Critical Role For Camkii In Behavioral Timescale Synaptic Plasticity In Hippocampal Ca1 Pyramidal Neurons, Jeffrey C Magee Sep 2023

A Critical Role For Camkii In Behavioral Timescale Synaptic Plasticity In Hippocampal Ca1 Pyramidal Neurons, Jeffrey C Magee

Faculty, Staff and Students Publications

Behavioral timescale synaptic plasticity (BTSP) is a type of non-Hebbian synaptic plasticity reported to underlie place field formation. Despite this important function, the molecular mechanisms underlying BTSP are poorly understood. The α-calcium-calmodulin-dependent protein kinase II (αCaMKII) is activated by synaptic transmission-mediated calcium influx, and its subsequent phosphorylation is central to synaptic plasticity. Because the activity of αCaMKII is known to outlast the event triggering phosphorylation, we hypothesized that it could mediate the extended timescale of BTSP. To examine the role of αCaMKII in BTSP, we performed whole-cell in vivo and in vitro recordings in CA1 pyramidal neurons from mice engineered …

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Impact Of E-Resources In Promoting Reading Habits: A Study Among The Central Library Users Of University Of Rajshahi, Bangladesh, Dr. Partha Biplob Roy, Susmita Tarofder Misty, Zihadur Rahman, Dil Afroz Bente Aziz Sep 2023

Impact Of E-Resources In Promoting Reading Habits: A Study Among The Central Library Users Of University Of Rajshahi, Bangladesh, Dr. Partha Biplob Roy, Susmita Tarofder Misty, Zihadur Rahman, Dil Afroz Bente Aziz

Library Philosophy and Practice (e-journal)

The widespread adoption of electronic resources, particularly in the realm of reading books, has transformed the landscape of academic libraries across the globe. This study explores the impact of e-resources on the reading habits and preferences of Central Library users at the University of Rajshahi. By analyzing the attitudes and experiences of students, faculty, and researchers, this research sheds light on the significance of e-resources in modern-day learning environments. The core purposes of the study are to investigate the trend and impact of using electronic resources, to explore the reasons, to know the benefits of using e-resources by the students. …

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Issue 426: September 7-21, 2023, The Local Voice Sep 2023

Issue 426: September 7-21, 2023, The Local Voice

The Local Voice

No abstract provided.

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Aynor Church Council Minutes 2006, Aynor United Methodist Church Sep 2023

Aynor Church Council Minutes 2006, Aynor United Methodist Church

Methodist Local Church Records

No abstract provided.

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Aynor Church Council Minutes 2020, Aynor United Methodist Church Sep 2023

Aynor Church Council Minutes 2020, Aynor United Methodist Church

Methodist Local Church Records

No abstract provided.

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The Indiana Statesman, September 7, 2023, Indiana State University Sep 2023

The Indiana Statesman, September 7, 2023, Indiana State University

Student Newspaper

New form of plagiarism emerges; More books banned; A small win for LGBTQ+ rights in California

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Walking The Valk Alone, Steve Eskew Sep 2023

Walking The Valk Alone, Steve Eskew

Erma Bombeck Writers' Workshop Blog

Jogging? No thanks — de feet need no more agony. Mountain climbing? Impossible!

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An Evolutionary Pathway For Coping With Emerging Infectious Disease, Scott Lyell Gardner, Daniel R. Brooks, Walter A. Boeger, Eric P. Hoberg Sep 2023

An Evolutionary Pathway For Coping With Emerging Infectious Disease, Scott Lyell Gardner, Daniel R. Brooks, Walter A. Boeger, Eric P. Hoberg

Zea E-Books Collection

Emerging infectious disease (EID) represents an existential threat to humanity. EIDs are increasing in frequency and impact because of climate change and other human activities. We are losing the battle against EIDs because of improper assessment of the risk of EID. This stems from adherence to a failed paradigm of pathogen-host associations that suggests EIDs ought to be both unpredictable and rare. That, in turn, leads to policies suggesting that crisis response is the best we can do. Real-time and phylogenetic assessments show EIDs to be neither rare nor unpredictable—this is the parasite paradox that shows the failures of the …

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Astrocytes In Stroke-Induced Neurodegeneration: A Timeline, Eileen Collyer, Elena Blanco-Suarez Sep 2023

Astrocytes In Stroke-Induced Neurodegeneration: A Timeline, Eileen Collyer, Elena Blanco-Suarez

Farber Institute for Neuroscience Faculty Papers

Stroke is a condition characterized by sudden deprivation of blood flow to a brain region and defined by different post-injury phases, which involve various molecular and cellular cascades. At an early stage during the acute phase, fast initial cell death occurs, followed by inflammation and scarring. This is followed by a sub-acute or recovery phase when endogenous plasticity mechanisms may promote spontaneous recovery, depending on various factors that are yet to be completely understood. At later time points, stroke leads to greater neurodegeneration compared to healthy controls in both clinical and preclinical studies, this is evident during the chronic phase …

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Id213 Oral History, Uniting Cultures Sep 2023

Id213 Oral History, Uniting Cultures

Uniting Cultures: Who We Are, How We Got Here: Collecting Stories Oral History Collection

No abstract provided.

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The Montclarion, September 7, 2023, The Montclarion Sep 2023

The Montclarion, September 7, 2023, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

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Presence, Co-Occurrence, And Daily Intake Estimates Of Aflatoxins And Fumonisins In Maize Consumed In Food-Insecure Regions Of Western Honduras, Luis Sabillón, Jackeline Alvarado, Alejandra Leiva, Rodrigo Mendoza, Raúl Espinal, John F. Leslie, Andreia Bianchini Sep 2023

Presence, Co-Occurrence, And Daily Intake Estimates Of Aflatoxins And Fumonisins In Maize Consumed In Food-Insecure Regions Of Western Honduras, Luis Sabillón, Jackeline Alvarado, Alejandra Leiva, Rodrigo Mendoza, Raúl Espinal, John F. Leslie, Andreia Bianchini

Department of Food Science and Technology: Faculty Publications

Foodborne mycotoxins are a significant food safety risk in developing countries. Our objective was to determine the occurrence of and exposure levels to aflatoxins (AFs) and fumonisins (FBs) in maize intended for human and animal consumption in food-insecure regions of western Honduras. Total AFs and FBs were quantified with a monoclonal antibody-based affinity spectrofluorimetric method. FBs were detected in 614/631 samples of maize destined for human consumption at 0.3 to 41 mg/kg (mean, 2.7 mg/kg). Of the 614 positive samples, 147 had FB levels exceeding the U.S. Food and Drug Administration (FDA) advisory threshold of 4.0 mg/kg. AFs were detected …

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Nutrition-Related Experiences Of Women With Perinatal Depression During The Covid-19 Pandemic: A Qualitative Study, Dahlia Stott, Cynthia Klobodu, Lisa A. Chiarello, Bobbie Posmontier, Mona Egohail, Pamela A. Geller, June Andrews Horowitz, Brandy-Joe Milliron Sep 2023

Nutrition-Related Experiences Of Women With Perinatal Depression During The Covid-19 Pandemic: A Qualitative Study, Dahlia Stott, Cynthia Klobodu, Lisa A. Chiarello, Bobbie Posmontier, Mona Egohail, Pamela A. Geller, June Andrews Horowitz, Brandy-Joe Milliron

College of Nursing Faculty Papers & Presentations

Women with perinatal depression are at a high risk for unhealthy dietary behaviors but whether the coronavirus disease 2019 (COVID-19) pandemic has exacerbated this risk is unknown. Here we report the findings of a qualitative study exploring the impact of the COVID-19 pandemic on nutrition-related experiences of women with perinatal depression. Using a qualitative descriptive approach, in-depth interviews were conducted with 18 women with a history of perinatal depression and 10 healthcare providers. A semistructured format elicited how food and nutrition-related behaviors of women with perinatal depression were affected by the COVID-19 pandemic. Thematic analysis identified 4 themes related to …

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Toward Energy Transformation: Intelligent Decision-Making Model Based On Uncertainty Neutrosophic Theory, Mona Mohamed, Nissreen El-Saber Sep 2023

Toward Energy Transformation: Intelligent Decision-Making Model Based On Uncertainty Neutrosophic Theory, Mona Mohamed, Nissreen El-Saber

Neutrosophic Systems with Applications

There has been an increasing tendency for the generation of energy from diverse renewable resources because of the application of contemporary pollution mitigation and justification regulations. Precisely a consequence, choosing the best renewable energy source might be considered a challenging issue given the complexity of the future conditions in any society. Environmental, economic, social, and technical aspects are merely some of the factors that are taken into consideration while evaluating renewable energy sources (RnESs). The suitable RES selection problem, which relies on ambiguous and imprecise data, is also influenced by a variety of circumstances. Hence, this study constructs multi-stages intelligent …

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The Current - Volume 34 Issue 1, Nova Southeastern University Sep 2023

The Current - Volume 34 Issue 1, Nova Southeastern University

Student Newspapers

No abstract provided.

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Montana Kaimin, September 7, 2023, Students Of The University Of Montana, Missoula Sep 2023

Montana Kaimin, September 7, 2023, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

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Appendage Abnormalities In Spiders Induced By An Alternating Temperature Protocol In The Context Of Recent Advances In Molecular Spider Embryology, Teresa Napiorkowska, Julita Templin, Pawel Napiorkowski, Mark A. Townley Sep 2023

Appendage Abnormalities In Spiders Induced By An Alternating Temperature Protocol In The Context Of Recent Advances In Molecular Spider Embryology, Teresa Napiorkowska, Julita Templin, Pawel Napiorkowski, Mark A. Townley

Faculty Publications

In the literature there are numerous reports of developmental deformities in arthropods collected in their natural habitat. Since such teratogenically affected individuals are found purely by chance, the causes of their defects are unknown. Numerous potential physical, mechanical, chemical, and biological teratogens have been considered and tested in the laboratory. Thermal shocks, frequently used in teratological research on the spider Eratigena atrica, have led to deformities on both the prosoma and the opisthosoma. In the 2020/2021 breeding season, by applying alternating temperatures (14 °C and 32 °C, changed every 12 h) for the first 10 days of embryonic development, …

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2023-09-07 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee. Sep 2023

2023-09-07 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee.

Faculty Senate Records

The meeting minutes of the Institutional Animal Care and Use Committee for September 7, 2023.

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Stem Cell And Drug Delivery Systems For Promoting Angiogenesis And Myogenesis In Ischemic Limbs, Ning Gao Sep 2023

Stem Cell And Drug Delivery Systems For Promoting Angiogenesis And Myogenesis In Ischemic Limbs, Ning Gao

McKelvey School of Engineering Graduate Student Theses & Dissertations

Peripheral artery disease (PAD) is a widespread atherosclerotic disorder affecting more than 200 million people globally, with critical limb ischemia (CLI) being its most severe manifestation. Stem cell therapy has been a promising CLI treatment, but the harsh conditions in an ischemic limb, such as hypoxia, high reactive oxygen species (ROS) stress, and the lack of a support matrix, trophic factors, and nutrients, all compromise therapeutic efficacy by reducing the survival rate or function of transplanted cells. This thesis presents various biomaterial systems designed for stem cell and drug delivery to improve the cell microenvironment and promote angiogenesis and myogenesis …

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Reducing Brain Kynurenic Acid Synthesis Precludes Kynurenine-Induced Sleep Disturbances, Katherine M. Rentschler, Snezana Milosavljevic, Annalisa M. Baratta, Courtney J. Wright, Maria V. Piroli, Zachary Tentor, Homayoun Valafar, Christian O'Reilly, Ana Pocivavsek Sep 2023

Reducing Brain Kynurenic Acid Synthesis Precludes Kynurenine-Induced Sleep Disturbances, Katherine M. Rentschler, Snezana Milosavljevic, Annalisa M. Baratta, Courtney J. Wright, Maria V. Piroli, Zachary Tentor, Homayoun Valafar, Christian O'Reilly, Ana Pocivavsek

Publications

Patients with neurocognitive disorders often battle sleep disturbances. Kynurenic acid is a tryptophan metabolite of the kynurenine pathway implicated in the pathology of these illnesses. Modest increases in kynurenic acid, an antagonist at glutamatergic and cholinergic receptors, result in cognitive impairments and sleep dysfunction. We explored the hypothesis that inhibition of the kynurenic acid synthesising enzyme, kynurenine aminotransferase II, may alleviate sleep disturbances. At the start of the light phase, adult male and female Wistar rats received systemic injections of either: (i) vehicle; (ii) kynurenine (100 mg kg−1; i.p.); (iii) the kynurenine aminotransferase II inhibitor, PF-04859989 (30 mg kg−1; s.c.); …

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Covering Properties Via Neutrosophic B-Open Sets, Sudeep Dey, Gautam Chandra Ray Sep 2023

Covering Properties Via Neutrosophic B-Open Sets, Sudeep Dey, Gautam Chandra Ray

Neutrosophic Systems with Applications

The purpose of this article is to study some covering properties in neutrosophic topological spaces using neutrosophic b-open sets. We define neutrosophic b-open cover, neutrosophic b-compactness, neutrosophic countably b-compactness neutrosophic b-Lindelofness, neutrosophic local b-compactness and study various properties entangled with them. We study some covering properties involving neutrosophic continuous, neutrosophic b-continuous and neutrosophic b*-continuous functions. Lastly, we define neutrosophic base, neutrosophic subbase, neutrosophic second countability via neutrosophic b-open sets and investigate some properties.

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Heterogeneity Of Human Tissue-Resident Lymphocytes, Natalia Jaeger Sep 2023

Heterogeneity Of Human Tissue-Resident Lymphocytes, Natalia Jaeger

Arts & Sciences Graduate Student Theses and Dissertations

The immune system plays a critical role in maintaining tissue homeostasis and defending against pathogens. Recent discoveries have highlighted the significance of tissue-resident memory T cells (TRM) and Innate Lymphoid Cells (ILCs) in tissue immunity. TRM exhibit memory-like properties, persist long-term in various tissues, and express markers such as CD69, CD103, and transcription factors like Hobit and Blimp-1. Similarly, ILCs, considered the innate counterparts of T cells, are abundant at barrier organs and mucosal sites, sharing similar markers and transcriptional factors with TRM, and rapidly responding to insults. Unraveling the heterogeneity and function of tissue-resident lymphocytes is crucial for understanding …

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