Digital Commons Network^™

Development Of A Grease Resistant Barrier For Food Industry Applications, Mira Marino

Honors Theses

The objective of this project is to develop a grease-resistant barrier coating for paper-based food packaging and to evaluate the economic feasibility of implementing this coating system at an industrial scale. As demand increases, this project focuses on identifying an optimal pigment and binder combination that enhances barrier performance while maintaining cost-effectiveness. The primary goal was to maximize grease and moisture resistance of coated paper while ensuring the process is economically viable and compatible with existing paper mill operations.

The final plant design consists of one continuous stirred tank reactor (CSTR) and three centrifugal pumps integrated into an existing paper …

Rhesus Macaques With An Opa1 Mutation Demonstrate Features Of Autosomal Dominant Optic Atrophy, Tracy N Jaggers, Ana Ripolles-Garcia, Ala Moshiri, Brett D Story, Jun Wang, Rui Chen, Lucy G Moore, Leandro B C Teixeira, Jaeho Shim, Ana C Raposo, Maria Isabel Casanova, Sophie M Le, Sangwan Park, Laura J Young, Soohyun Kim, Karolina P Roszak, Vanessa Ureno, Paige M Karpinen, Nayeli Echeverria, Monica Ardon, Brian C Leonard, Marguerite Knipe, Eliza Bliss-Moreau, Brad Fortune, J Timothy Stout, Jeffrey Rogers, Nicholas Marsh-Armstrong, Sara M Thomasy

Faculty, Staff and Students Publications

Autosomal dominant optic atrophy (ADOA) is an inherited optic neuropathy primarily caused by mutations in OPA1. We identified and defined a spontaneous nonhuman primate (NHP) model of ADOA using rhesus macaques heterozygous for a missense mutation (OPA1A8S). With ocular examinations, ophthalmic imaging, electroretinography, histopathology, immunohistochemistry, and transmission electron microscopy (TEM), we documented retinal nerve fiber layer (RNFL) thinning, retinal ganglion cell (RGC) loss and dysfunction, OPA1 mislocalization, and reduced axonal mitochondrial density in affected macaques. Our investigation revealed substantial phenotypic variability among affected macaques, shedding light on the pathogenesis of ADOA. The retinas were evaluated using techniques …

Development Of Telenutrition Education And Counseling Protocol To Improve Diet Quality In Individuals With Spinal Cord Injury, Adrianne Widaman, Benjamin Dirlikov, Ramya Gopalan, Shelley Wood, Maria Sol Casas, Kazuko Shem

Faculty Research, Scholarly, and Creative Activity

Background: Cardiometabolic disease (CMD) is a leading cause of death for individuals living with chronic spinal cord injury (SCI), with a mortality rate due to CMD being higher than individuals without SCI. Telenutrition (TN) interventions tailored to health and accessibility needs of individuals with SCI may mitigate cardiometabolic risks. Objectives: To describe the development and validation of a telehealth-based medical nutrition therapy (MNT) within a clinical trial investigating the effectiveness of modifying diets to improve cardiometabolic health in persons with chronic SCI. Methods: The adaptive module-based MNT education content was developed in 3 phases by a multidisciplinary team. The first …

Enhancing Inference Of Differential Gene Expression In Metatranscriptomes From Human Microbial Communities, Evan M Lee, Nathan P Mcnulty, Matthew C Hibberd, Jiye Cheng, Kazi Ahsan, Hao-Wei Chang, Barak A Cohen, Jeffrey I Gordon

2020-Current year OA Pubs

Metatranscriptomic (MTX) sequencing quantifies gene expression from the collective genomes of microbial communities (microbiomes), enabling assessment of functional activity rather than functional potential. While differential expression testing is essential for RNA-sequencing analysis, current metatranscriptomic approaches have only been benchmarked on simulated data, resulting in a lack of standard practices for analysis of real datasets. Here, we use mock communities (defined mixtures of microbial cells with known properties) to quantitatively assess robustness and susceptibility of current approaches to various confounders including organisms' low relative abundance, differential abundance, low prevalence, global transcriptional output changes, and compositional effects. We show that no current …

Construction And Characterization Of Novel Mycobacterium Tuberculosis-Derived Triple And Quadruple Knockout Vaccines Against Tuberculosis, Omar Garnica, Raja Veerapandian, Kishore Das, Abhishek Mishra, Varsha Rawat, Areanna Carmona, Vivek Chauhan, Rakesh Kumar, Jessica Chacon, Shrikanth S. Gadad, Subramanian Dhandayuthapani

School of Medicine Publications

Tuberculosis (TB) is a deadly disease that claims the lives of over a million people each year worldwide. The Bacille Calmette-Guérin vaccine has long been used to protect against TB, but it produces variable effects across different populations and fails to protect against adult pulmonary TB. Therefore, there is an urgent need for alternative vaccines that can offer better protection. We have developed a strategy for the rational deletion of virulence-related genes in Mycobacterium tuberculosis (Mtb) to create hyperattenuation that also enhances immunogenicity. Previously, we generated both single (∆fbpA) and double knockout (DKO) (∆fbpA-∆sapM) mutants of …

Create @ State 2026, Arkansas State University - Jonesboro

Create@State

Proceedings for 2026

Exploring The Antimicrobial Properties Of Spotted Lanternfly Contaminated Honey, Davanna Mcclellan

Liberty University Research Week

This study aims to investigate how the antimicrobial properties of pure honey and spotted lanternfly contaminated honey differ. The spotted lanternfly (Lycorma delicatula) is an invasive species that has been in the U.S. since 2014. This species has wreaked havoc on many different industries, such as the agricultural and tobacco industries. However, the relationship between the lanternfly and the European honey bee (Apis mellifera) has not been researched. One facet of their relationship shows that honey bees will use lanternfly secretions called honeydew to make honey. Honey possesses antimicrobial and anti-inflammatory qualities due to the antimicrobial peptides present within honey …

Distribution Of Virginia Pollinator Insect Specimens From The Liberty University Natural History Collection, Sarah Gerringer

Liberty University Research Week

The Liberty University natural history collection contains a substantial number of preserved insect specimens taken from all over the state of Virginia, and which includes many families of pollinator insects. Pollinator insects play an important part in life on this planet, so the purpose of this study was to visually represent and evaluate historical pollinator habitat data. Information such as this can be used to both spread awareness of pollinator conservation and to provide a better understanding of where pollinators may be located. In this study, we compiled and examined location data from ten families of Virginia native pollinator insects …

Is Everything Awesome? Cultural Apologetics In A Metamodern Age, Alexander Lee, Dara Huamanchumo Ascanio, Isaiah Johnson

Liberty University Research Week

Contemporary apologists have emphasized that engaging with culture in an insightful and respectful way is a powerful tool for evangelism (Chatraw & Allen, 2018). In this vein, children’s media, born in a specific cultural setting, has a formative impact on upcoming generations, an avenue of influence that should be explored for its implications in apologetics. To do this, the research explores themes highlighting the transition between postmodernism and metamodernism by comparing the films Toy Story (1995) and The Lego Movie (2014). The project figures characters in Toy Story as representing the shift from modernism to postmodernism, while characters in The …

Breastfeeding And Infant Health In Virginia: A Systematic Review (2015-2025), Haley Gebhard, Rebecca Martha Nantale, Tahirou Diallo, Treasure Nkemdilim James, Yiwei Huang

Liberty University Research Week

Breastfeeding has long been recognized as the optimal nutritional option for infants due to its extensive health benefits for both infants and mothers. According to the World Health Organization (WHO), early initiation and exclusive breastfeeding serve as protective factors infant morbidity and mortality.1 Despite the knowledge on breastfeeding and its significance to infant growth and development, breastfeeding rates remain suboptimal worldwide. Even in the U.S., public health has identified increasing breastfeeding rates as a national goal, especially targeting low-income areas. The purpose of this study is to systematically identify and evaluate studies examining breastfeeding practices and infant outcomes among the …

Rapid Challenges In Infectious Disease And Mosquito-Borne Parasite Detection, Carrington Vines

Liberty University Research Week

This project examines the diagnostic challenges facing "frontier" labs in regions like Lynchburg, VA, and rural Alaska. It contrasts the "Old Guard" (manual microscopy) with the "New Guard" (PCR/ELISA), highlighting a performance jump from 70% to 98% sensitivity. However, this precision is met by a "Financial Reality" check: costs spike from $10 to over $150 per test, creating a barrier for low-volume rural clinics. To bridge this gap, the study proposes Vector-Informed Care—using mosquito surveillance as an early warning system to deploy expensive molecular tools efficiently. Grounded in the biblical mandate of the "Watchman" (Ezekiel 33:7), this hybrid strategy ensures …

What Bombs Cannot Occupy: Memory, Heritage, And War In Ukraine, Dalton D. Conden

The Penguin Review

Air-raid sirens have become part of the daily soundscape in Ukrainian cities. They interrupt meals, classes, conversations, and sleep. When they blare, people gather what they can and move quickly sometimes to shelters, sometimes to basements, sometimes nowhere at all. Families lock their doors without knowing whether they will ever turn the key again. Children carry backpacks filled with whatever seemed important in the moment: a photograph, a stuffed animal, a book pulled hastily from a shelf. Around them, buildings that once anchored everyday life—churches, museums, historic neighborhoods— have been damaged or destroyed.

New Ways To Address The Plastic Problem, Andrew J. Hanna

The Penguin Review

Since 1950, the world has produced some 9.2 billion metric tonnes of plastic.1 Other sources place the total closer to ten billion metric tonnes Furthermore, nearly 500 million tonnes of new plastic are manufactured each year– a figure that's projected to increase to 1.2 billion tonnes by 2060.2 The environmental effects of all this plastic production and pollution are disturbing. Because most plastics are synthetic–meaning they contain "no molecules found in nature"– they can't decompose. Instead, they just break down into smaller and smaller pieces, becoming microplastics (less than five millimeters (5 million nanometers) across) and then nanoplastics (less than …

Fighting For The Story: How Identity Shapes The Israel–Hamas War, Ana Lilia Zavala

The Penguin Review

The war between the state of Israel and the militant group Hamas is often portrayed in strictly strategic or material terms, from rockets and tunnels to ground offensives and massive casualties. Yet what truly lies at the core of the conflict in the Gaza Strip is not merely a struggle over territory or security, but a struggle of identities, narratives, and legacies of harm. From my constructivist standpoint, I believe that actors act not just because of “national interests,” but because of how they understand their own identity, how they interpret the other, and how normative structures shape their choices. …

The Digital Museum: Classical Reception In Animal Crossing New Horizons, Anna G. Kendall

Create@State

My project examines how Animal Crossing: New Horizons brings the ancient body into a modern, digital world through its recreations of classical Greek sculptures. In the game, players can collect, study, and display famous works such as the Venus de Milo, Discobolus, and Nike of Samothrace in a virtual museum. These sculptures reveal how the Greeks represented beauty, strength, and divine movement through the human form. By interacting with them in-game, players connect with these ancient ideas of the body in a new way. The game’s system of real and fake artworks also teaches players to look closely and …

Purr-Spectives: Connections Between Feline Coat Color And Human Preferences And Perceptions In Northeast Arkansas, Tiffany L. Batchelor

Create@State

Felines have played an important role in the lives of humans for thousands of years. This study investigated perceptions of felines and feline demographics in Northeast Arkansas (NEA). For Study 1, data on phenotype and health conditions was collected from 2,305 patient files from three NEA veterinary clinics. For Study 2, an anonymous survey generated using Qualtrics was published through College of Agriculture social media accounts to gather opinions from cat owners on feline coat color and ownership trends. Study 1 identified up to 6 pattern-based and up to 18 color-based phenotypes per clinic and a total of 129 unique …

Prioritizing Health Over Aesthetics: Reforming Brachycephalic Breed Standards, Olivia Edwards

Create@State

Selective breeding has led to extreme physical traits in companion animals such as dogs and cats. They are characterized by their shortened skulls, creating their flattened faces. These breeds remain fairly popular due to their appearance, even though these animals present various health concerns.  I conducted this research at A-state to create awareness and educate those who are not aware of this issue, and for future pet owners. It argues that the continued promotion and recognition of these animals contributes to preventable health conditions and long-term suffering in affected animals. I analyzed reports on animal welfare, reviewed policy discussions and …

Skin Pattern As A Potential Monitoring Tool For Frog Populations, Lídize Sagarnaga Rivera, Virginie Rolland Dr., Lorin Neuman-Lee Dr.

Create@State

Skin pattern as a potential monitoring tool for frog populations

Population monitoring, which requires identifying individuals, is crucial for species conservation. Common techniques involve marking, which can harm animals and alter their behaviors. Natural markings are an alternative not yet explored for amphibians. Yet, the traditional method with elastomers (fluorescent implants) is invasive and not completely reliable—the tag may become lost or hard to see. The American green tree frog (Dryophytes cinereus) possesses naturally occurring and distinct golden dots on their dorsal side.  Therefore, we aim to assess whether patterns of golden dots on the skin of green …

Student Perspectives On The Selection And Suitability Of Emotional Support Animals, Ella G. Speer

Create@State

Emotional support animals (ESA) are classified as any species of animal that provides cognitive and emotional benefits for individuals struggling with mental health impairments (Ferrell, Crowley 2021, p. 561). Emotional support animals differ from service and therapy animals because there are no restrictions regarding the specie selection if the owner perceives their benefits (Ferrell, Crowley 2021, p. 561). Relaxed regulations on the specie of emotional support animals allow individuals the opportunity to choose any animal based on their perceived benefits (Pettable Staff, Fleming 2024). Recently, universities have implemented an emotional support animal policy to protect students who live on campus …

Amyloid Beta-42 Neurotoxicity In Drosophila Retinal Development, Shay O. Sims, Pierce Duncan, Malachi Abon, Jacob G. Smith

Create@State

Alzheimer's disease (AD) represents one of the most prevalent neurodegenerative disorders globally. Thus far, the underlying mechanisms associated with the pathogenesis of AD are innately elusive. Two hallmarks associated with the progression of AD exist, including Amyloid-Beta 42 (Aβ42) protein plaque formation and hyperphosphorylation of tau proteins in neurons. Amyloid-beta is known to concentrate with other neuronal proteins as complexes form, including the cytoskeletal protein actin. However, whether actin contributes to neuronal decline in AD is unknown. To further understand the cellular cascades associated with AD, we investigated the role of cytoskeleton dynamics in modulating oxidative stress and neuroinflammation within …

Reframing Alpha-Gal Syndrome As A One Health Oral Health Risk: A Theoretical Model For Dental Safety And Policy Reform, Oyebolu Aderinola Akinkugbe, Akuchinyere Titus-Okpanachi, Oluwatosin Marylyn Oduneye

Liberty University Research Week

No abstract provided.

Inc3vits Model: A Hybrid Architecture To Accelerate And Reduce Complexity For The Deepvariant Model For Variant Calling, Mustafa Al-Saffar, Sura Z. Al Rashid

Karbala International Journal of Modern Science

Deep learning has revolutionized genomic variant calling, yet the computational cost of current systems continues to limit scalability. We present a controlled efficiency study of DeepVariant-style pileup architectures under identical training and inference conditions, comparing architectural downsizing with a hybrid CNN–local attention design. Inc3ViTs pairs a streamlined InceptionV3 stem with a lightweight local attention head based on patch tokenization and windowed self-attention, enabling a direct comparison with a CNN-only reduced Inception baseline. Across whole-genome and whole-exome short-read datasets, Inc3ViTs reduces training time by ~40–50% and reduces inference runtime relative to the original DeepVariant. The CNN-only baseline indicates that most speedups …

Behind The Scenes - Anthony Cheung

V Music Magazine

No abstract provided.

Vol. 1 Full Issue

V Music Magazine

No abstract provided.

Melody Of Wrath: A Retelling Of The Pied Piper, India Raye Sorensen

Theses and Dissertations

Melody of Wrath is a young adult fairy tale retelling of the Pied Piper legend centered on fifteen-year-old antihero Magnus. Driven by grief and rage after the massacre of his people, Magnus wields music as dangerous magic to summon a plague of rats and exact revenge on a corrupt city. The novel follows his morally complex journey from vengeance through compromise to a final test inside a transformative mountain, where he confronts the cost of retribution and the uncertain possibility of redemption. Drawing on folktale scholarship, archetypal theory, and literary antiheroes such as Hamlet and Edmond Dantès, this project uses …

Swosu Research And Scholarly Activity Fair 2026, Swosu Office Of Sponsored Programs

SWOSU Research and Scholarly Activity Fair Programs

On behalf of the University Research and Scholarly Activity Committee (URSAC) and the Office of Sponsored Programs (OSP) at Southwestern Oklahoma State University, we are pleased to welcome you to the Thirty-Fourth SWOSU Research and Scholarly Activity Fair.

Long Work Hours, Suboptimal Diabetes Management, And Differences By Sex And Race/Ethnicity, Nhanes (2011-2018), Tailisha Gonzalez, Margrethe Horlyck-Romanovsky, Terry T.-K. Huang, Sandra E. Echeverria

Publications and Research

In the United States (US), occupational segregation by sex and race/ethnicity can contribute to health disparities. Although work schedule characteristics have been previously linked to elevated cardiovascular risk, little is known about the effects on chronic disease management in women and minoritized workers. We examined the association between work hours and diabetes management among US workers, testing for differences by sex and race/ethnicity. We utilized 2011–2018 National Health and Nutrition Examination Survey (NHANES) data on working adults (age ≥20 years) with diagnosed diabetes (n = 1041). Suboptimal diabetes management was defined as HbA1c ≥7%. Work hours were categorized per WHO …

A Study Of Zomi Pentecostalism In Its Social, Cultural, And Political Context: A Pentecostal Quest For The Lost Paradise, Thang San Mung

College of Theology and Ministry Dissertations, Projects, & Theses

This dissertation examines the paradisal quest of the Zomi people, an ethnic Christian minority in Myanmar, through the lens of Pentecostal spirituality. Historically, the Zomi have experienced political displacement, loss of their ancestral homeland (Zogam), and ongoing marginalization. While existing scholarship has primarily interpreted Zomi struggles in terms of ethnic identity, nationalism, and socio-political resistance, this study offers a theological reorientation by interpreting Zomi paradisal longing through the Spirit-Restored Paradise framework, a Pentecostal theological model developed here. Employing a qualitative ethnographic methodology grounded in contextual theology, the research draws on semi-structured interviews with twenty-four Zomi Pentecostal participants from Myanmar and …

Elasmobranchii Oral Microbiome Diversity Within Southeast Florida: Implications Of Shark Zoonotic And Antibiotic Resistant Pathogens Associated With Human Interactions, Amanda Finnefrock

All HCAS Student Capstones, Theses, and Dissertations

Sharks are incredibly common in the Atlantic and Gulf waters surrounding Florida. Despite the prevalent nature of these animals, little research exists on the composition of their microbial communities (or “microbiomes”). Here we aim to determine the microbial makeup of the oral environment of sharks so that we can determine if there are any bacteria of clinical significance to humans, such as being antibiotic-resistant or having elevated capability for pathogenicity. A total of 41 samples were collected from the mouths and teeth of bull, Caribbean reef, great hammerhead, lemon, nurse, and sandbar sharks caught in Southeast Florida using sterile swabs …

Pharmacological Treatment Options For Vasoplegia Syndrome During And After Cardiopulmonary Bypass: A Scoping Review, Bradley Darby

Student Works

ABSTRACT

2: Structured summary

Background

Vasoplegia Syndrome (VS) is a form of distributive shock that is characterized by profound hypotension, low systemic vascular resistance, and high to normal cardiac output during/after cardiopulmonary bypass. VS is associated with increased mortality, morbidity, and length of stay in the intensive care unit.

Objective

The main objectives of this scoping review are to note the available treatment options, characterize potential risk factors, and identify gaps in knowledge for vasoplegia syndrome during and after cardiopulmonary bypass.

Method

This scoping review utilized the Preferred Reporting Items for Systematic reviews and MetaAnalyses extension for Scoping Reviews (PRISMA-ScR) …