Digital Commons Network^™

Feminist Use, Amanda Levendowski

Georgetown Law Faculty Publications and Other Works

In 2015, Judge Pierre Leval wrote that copyright isn’t about authors, it’s about the rest of us. “While authors are undoubtedly important intended beneficiaries of copyright,” he explained, “the primary intended beneficiary is the public.” He would know—his scholarship has been transformative for how every jurist from the Supreme Court down approaches key copyright questions. But copyright often falls short of this aspiration by benefiting only a sliver of the public.

Copyright law grants exclusive rights to authors of qualifying works, such as books, which protects those works from unauthorized copying. The first copyright legislation, the Statute of Anne of …

Electromechanical Mapping Of The In Vivo Porcine Heart And Stomach, Haley Nesmith Patton

All ETDs from UAB

Electrical excitation and mechanical function are integral to the physiologic activity of both the heart and stomach. Electrical depolarization through the myocardium triggers contraction in the heart. When normal sequences of electrical activity are disturbed, the heart’s mechanical function may also be disturbed, affecting its ability to pump blood effectively, sometimes fatally. Similarly, electrical waves called slow waves initiate gastric peristalsis. Abnormalities in slow wave propagation patterns can disturb the stomach’s ability to mechanically process gastric contents, sometimes resulting in delayed gastric emptying, nausea, and vomiting. The relationship between mechanical function and electrophysiology is not unidirectional, though. Mechanical stimuli can …

The Role Of Fibroblast Growth Factor Receptors In Inflammatory Airway Diseases, Molly Easter

All ETDs from UAB

Chronic inflammation plays a role in the development and progression of airway diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). COPD is caused primarily by chronic cigarette smoke exposure. Conversely, CF is a single gene disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). Although the causes of COPD and CF are different, there are common pathological features. Studies show that chronic inflammation plays a significant role in the pathogenesis of both COPD and CF. Moreover, chronic inflammation induces ageing-associated pathomechanisms like cellular senescence, which exacerbates chronic inflammation. Previous work demonstrates that …

Genotype And Sex Specific Effects Of Methionine Restriction On The Life And Healthspan Of Drosophila Melanogaster, Joshua Robert Smith

All ETDs from UAB

Reduced dietary intake of the amino acid methionine has been reported to significantly extend the lifespan of common laboratory model organisms including Saccharomyces cerevisiae, Mus musculus, and Drosophila melanogaster. Methionine restriction (MR) has also been achieved via non-dietary means such as metabolite supplementation and CRISPR-Cas9 gene editing. MR along with protein and calorie restriction are known as dietary interventions capable of producing pro-longevity benefits through regulation of nutrient sensing pathways. Recent studies in model organisms have also identified beneficial effects of a low methionine diet on aging-associated phenotypes and markers of overall healthspan. However, the effects of this intervention on …

Characterizing The Reproductive System Of Avrainvillea In HawaiʻI, Brinkley Mikayla Thornton

All ETDs from UAB

Sex has generated incredible life cycle diversity across eukaryotes. Differences in the timing of meiosis and fertilization have generated tremendous variation in the duration of haploid and diploid phases. To understand what drives eukaryotic sexual diversity, there remains a need to determine the rates of sexual and asexual reproduction in natural populations. Moreover, life cycle diversity is predicted to be correlated with the reproductive system. Yet, most studies on reproductive variation have focused on diploid or diploid dominant organisms, hindering the ability to understand sex. Macroalgae can serve as useful models to overcome this limitation via life cycle and reproductive …

The Impact Of O-Glcnac Signaling On Dna Hydroxymethylation In Temporal Lobe Epilepsy, Rudhab Bahabry

All ETDs from UAB

Temporal Lobe Epilepsy (TLE) is the most prevalent form of focal epilepsy and the most treatment-resistant type. This condition is characterized by recurrent, unprovoked seizures typically originating in the hippocampus. Epigenetic modifications such as DNAme changes have been implicated in brain functions such as synaptic plasticity, learning and, memory, and cognition. The oxidation of DNA 5-methylcytosine (5-mC) and its oxidized form, 5-hydroxymethylcytosine (5-hmC) catalyzed by Ten-Eleven Translocation (TET) family of dioxygenases and linked to epilepsy's hyperexcitable state. Post‐translational modifications (PTMs) of proteins, such as O-GlcNAcylation, facilitate cells' immediate responses to intracellular or extracellular environmental stimuli by modifying the functions of …

Evaluation Of Feed Intake, Growth, And Reproduction In The Zebrafish, Danio Rerio, Fed A Gel-Based Diet, Thomas Logan Holfelder

All ETDs from UAB

EVALUATION OF FEED INTAKE, GROWTH, AND REPRODUCTION IN THE ZEBRAFISH, DANIO RERIO, FED A GEL-BASED DIET THOMAS LOGAN HOLFELDER BIOLOGY ABSTRACT The zebrafish, Danio rerio, is a valuable pre-clinical model, aiding human health understanding and translational aquaculture. Comprehensive documentation of the culture of this model exists, with ongoing efforts to optimize husbandry requirements, particularly in the areas of diet and nutrition. Labor or mechanical costs related to feeding are high in most laboratories and alternative protocols to reduce feed handling would be beneficial and could allow the capability to monitor feed consumption. A commercially produced gel-based diet has a high …

Town Of Lempster, New Hampshire, Incorporated 1767, Annual Reports For The Year Ending December 31, 2023., Lempster Town Representatives

Lempster, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Analysis Of The Immune Response After Readministration Of A Novel Aav6 Gene Therapy Containing Tlr9 Inhibitory Sequences, Sarah Elysse Allen

MUSC Theses and Dissertations

Therapeutic options for the treatment of Surfactant Protein-B (SP-B) deficiency, an autosomal recessive disorder that leads to fatal respiratory distress, are extremely limited with the exception of double lung transplantation. One method for treating this monogenic lung disease is with adeno-associated virus (AAV) gene therapy treatment that delivers the hSFTPB transgene into the lungs. The transient nature of AAV transgene expression led to a need for sustained gene expression, which could possibly be achieved through redosing. The main obstacle with redosing is the innate immune response and subsequent inflammatory response pathways that are activated after recognition of unmethylated CpG motifs …

Adult Learners Self-Derive New Knowledge Through Integration Of Novel Information And Prior Knowledge And Are More Successful With Reactivation, Jayantika Chakraborty, Alena G. Esposito

Psychology

Self-derivation through integration is the process of integrating novel facts and producing new knowledge never directly taught. Knowledge integration has been studied with the presentation of two novel facts. However, in educational settings, individuals are required to integrate new information with prior knowledge learned days, months, or years earlier. Prior knowledge robustly predicts learning outcomes, but less is known about self-derivation through the integration of new information with prior knowledge. Thus, in Study 1, we examined adults' (n = 25) memory integration of new facts with prior knowledge. The participants had 52% accuracy in self-derivation. In Study 2 (n = …

Belugas (Delphinapterus Leucas) Create Facial Displays During Social Interactions By Changing The Shape Of Their Melons, Justin T. Richard, Isabelle Pellegrini, Rachael Levine

Fisheries, Animal and Veterinary Sciences Faculty Publications

Beluga whales are considered unique among odontocetes in their ability to visibly alter the appearance of their head by changing the shape of the melon, but only anecdotal observations are available to evaluate the use or potential function of these melon shapes. This study of belugas in professionally managed care aimed to establish an ethogram for the repertoire of categorizable melon shapes and then evaluate their potential function as intentional communication signals by determining if they were produced and elaborated during social interactions of varying behavioral contexts while in the line of sight of a recipient. Five different melon shapes …

Behavioral Interactions And Mate Compatibility Influence The Reproductive Success Of New England Cottontails (Sylvilagus Transitionalis) In A Conservation Breeding Program, Hannah Petit, Louis Perrotti, Justin T. Richard

Fisheries, Animal and Veterinary Sciences Faculty Publications

Wild populations of New England cottontails (NECs, Sylvilagus transitionalis) are declining and occupy a small proportion of their historic range. To conserve this species, wild-caught cottontails participate in a reintroduction breeding program. To increase the program’s productivity, this study described breeding behavior in pairings with (n = 3 pairings) and without (n = 9 pairings) reproductive success. Females were paired with two males consecutively and behaviors were recorded using 24 h continuous video footage. Activity peaked between 19:00 and 06:00. Copulation was only observed in successful pairings, and the gestation period was 31 days. Successful pairings had …

Characterization Of Antibody Repertoires Developed From Naive And Recall Responses, Nicholas C. Curtis

Dartmouth College Ph.D Dissertations

Adaptive immunity, comprised in part by the antibody repertoire, is the cornerstone of our ability to remain healthy amongst the plethora of pathogenic challenges we encounter daily. Despite the importance of understanding antibody repertoire development, much remains unknown about the composition and evolution of circulating antibodies in response to viral challenges. To better understand antibody repertoire development, we profiled the serum antibody repertoire using a combination of next-generation sequencing and serum antibody proteomics in the predominantly naïve response against SARS-CoV-2 spike and the recalled response to influenza hemagglutinin. The response to SARS-CoV-2 spike in four convalescent individuals was diverse (consisting …

The Mediating Role Of Sense Of Coherence In The Relationship Between Positive Childhood Experiences And Alexithymia, Ummu Erturk Yıldız, İbrahim Taş

Khazar Journal of Humanities and Social Sciences

This study examined the mediating role of the sense of coherence in the relationship between positive childhood experiences and alexithymia. The research was conducted with a total of 507 participants, including 259 women and 248 men aged over 18, selected through convenience sampling. Data were collected using a Personal Information Form, the Positive Childhood Experiences Scale, the Toronto Alexithymia Scale, and the Sense of Coherence Scale. Data analysis was performed using SPSS 25 and the PROCESS macro. The results indicated that positive childhood experiences significantly and positively predicted levels of sense of coherence, while they significantly and negatively predicted alexithymia. …

Bfa Studio Art, 2024-25, Arkansas State University - Jonesboro

Bachelor of Arts and others

No abstract provided.

Cjc Project_Calea_Middletown Police Department Citizen Satisfaction Survey_2024, Robert J. Hehl

Faculty and Staff - Articles & Papers

During the months of January through April 2, 2024, Department of Criminal Justice and Criminology (CJC) students from Salve Regina University in Newport, Rhode Island, conducted a survey on the performance of the Middletown Police Department (MPD) and its personnel. Of the 314 total responses received, 103 responses were received via online collection and 211 responses were received via survey letter response. Under the direction of Professor Robert Hehl, the research team included the following students: Victoria Garcia, Mary Evans, Tim McGuire.

Enhancing Green Sea Urchin (Strongylocentrotus Drobachiensis) Production Toward Sustainability, Tara Plee

Open Access Dissertations

The green sea urchin (Strongylocentrotus droebachiensis) fishery was once prosperous in the Gulf of Maine, peaking in the 1980s and early 1990s. However, since the early 1990s, the fishery has dramatically declined despite having harvesting restrictions. To sustain the industry, production through aquaculture is necessary, but hatchery production methods are not yet optimized, with settlement success and post-settlement survival as low as 1-5%, and the spatial scale for field grow-out may be limited in some regions due to climate change. Additionally, there are knowledge gaps in fishery management regarding whether oversized S. droebachiensis help sustain natural stocks. This …

Otherness, Belonging, And Production Of Space : The Case Of Amenity Migration In Fethiye, Türkiye, Ece Buldan

NAKHARA (Journal of Environmental Design and Planning)

The article delves into the intricate dynamics of amenity migration and rural gentrification, investigating the challenges that arise when residents and newcomers encounter. Amenity migration, which occurs when individuals relocate to an area in search of desirable features, often leads to rural gentrification. This process involves economic and social changes brought about by the arrival of wealthier residents. While amenity migration can bring economic advantages, it also presents difficulties such as displacement and cultural transformations within the community. The study recognizes the concept of "otherness" is introduced to shed light on potential cultural and social conflicts between amenity migrants and …

The Mapping Of Sensemaking Territories Through Physical And Social Media : A Case Of The Historical Bazaar Of Kemeraltı, Izmir, Ömer Can Bakan, Deniz Engin, Fatma İpek Ek

NAKHARA (Journal of Environmental Design and Planning)

The paper aims to analyze and make visible the intertwined layers of a palimpsest territory, such as the historical bazaar of Kemeraltı in Izmir, Turkey, through the lens of architecture students concerning their perceptions of producing Instagrammable visual data to influence and attract the prospective visitors and to compensate the lack of interest in the bazaar as mentioned by local institutions. Through this analysis, we also aim to conduct a methodological experiment that recognizes social media as a cognitive tool by combining digital and physical representations. The study encompasses a one-month workshop for students of the visualization in an elective …

American Star Chamber: Online Misinformation, Government Intervention, And The Intellectual Matrix Of The First Amendment, Emily E. Burton

Catholic University Journal of Law and Technology

Just as monarchs and clerical authorities struggled to respond to seditious and heretical writings enabled by the invention of the printing press, twenty-first century governments are experiencing a similar information revolution as a result of the digital age and a rising tide of what the United States has labeled online misinformation. Like the printing press, the Internet has enabled the spread of information at an exponentially lower cost and an exponentially higher speed as it extends the ability to publish thoughts and opinions to an increasingly diverse array of individuals. Although this was largely celebrated during the first two decades …

State Barrier Fence - Esperance Extension Project Overview 2024, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

Western Australia’s State Barrier Fence plays an important role in protecting landholders inside the fence by preventing the movement of animal pests, including wild dogs and emus, from pastoral areas into the agricultural regions. It is a state asset which is managed by the Department of Primary Industries and Regional Development.

The original fences (numbers 1, 2 and 3) were constructed between 1902 and 1907. Originally known as the Rabbit Proof Fences, it has also been known as the State Vermin Fence, the Emu Fence and now the State Barrier Fence. Since 2010, the fence has been upgraded to wild …

Project Portfolio: Spiritual Sexuality A Guidebook For Parents, Kelly Edmiston

Doctor of Ministry

In this project portfolio, I will address the following NPO: Christian parents of school-aged children don’t know what to teach their children about sex.

As the Lead Pastor of the Vineyard Church of Sugar Land/Stafford, I found that Christians lack integration between sexuality and spirituality. Kids and teens learn about sex from the media, and they learn about spirituality from parents and church. This led me to focus my project on an integration between the two. Spiritual sexuality is a guidebook for parents of school-aged children. In my research, I found that parents feel overwhelmed and ill-equipped to lead their …

Project Portfolio: Stronger Together Virtual Clergy Groups In Small Congregations, John Fillmore

Doctor of Ministry

Ministers in small congregations suffer from isolation and a lack of personal and professional relationships that can encourage and equip them for more effective ministry. Ministry in smaller congregations combines the common continuous responsibilities of pastoral ministry in a context in which pastors are often overburdened with competing expectations and demands. Often serving as a solo minister, clergy are isolated in dispersed congregational settings and struggle to find time to participate in supportive relationships with other pastors. Utilizing discovery workshops and numerous qualitative interviews, this project found a nearly universal desire for meaningful relationships between pastors, as well as consistent …

Project Portfolio: Connecting Women With God Through Reflective Spiritual Practices, Victoria Niebrugge

Doctor of Ministry

Although there are various learning offerings within the context of the church, women can experience a disconnect between the head and the heart, between knowing about God and knowing God. The women involved in this study hunger for greater intimacy with God. They attend weekend worship services and weekly church Bible studies. Yet, they say they know there is more of God, desire to know Him more profoundly, and are searching for a deeper relationship with Him.

The roots of the practices used for spiritual formation today are found in the ancient rhythms of the desert mothers and fathers of …

Inflammation And Tumor Progression: The Differential Impact Of Saa In Breast Cancer Models, Daniel Wilhelm Olivier, Carla Eksteen, Manisha Du Plessis, Louis De Jager, Lize Engelbrecht, Nathaniel Wade Mcgregor, Preetha Shridas, Frederick C. De Beer, Willem J. S. De Villiers, Etheresia Pretorius, Anna-Mart Engelbrecht

Saha Cardiovascular Research Center Faculty Publications

Background: Previous research has shown that the Serum Amyloid A (SAA) protein family is intricately involved in inflammatory signaling and various disease pathologies. We have previously demonstrated that SAA is associated with increased colitis disease severity and the promotion of tumorigenesis. However, the specific role of SAA proteins in breast cancer pathology remains unclear. Therefore, we investigated the role of systemic SAA1 and SAA2 (SAA1/2) in a triple-negative breast cancer mouse model.

Methods: Syngeneic breast tumors were established in wild-type mice, and mice lacking the SAA1/2 (SAADKO). Subsequently, tumor volume was monitored, species survival determined, the inflammatory profiles of mice …

Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co

Bioengineering Dissertations - Archive

Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.

Long-term patient …

2024 Tnecd Annual Report, Tennessee. Department Of Economic And Community Development

Annual Reports

The TNECD annual report highlights the accomplishments of the agency in developing business across the state for the fiscal year.

The Relationship Between Secondary Ela Teacher Pedagogical Practices, Student Self-Regulated Learning And Digital Self-Efficacy In A Blended Learning Environment, Melissa K. Miller

Dissertations

In the era of emerging technologies in the 21st Century classroom, secondary English Language Arts (ELA) students may exhibit complications in navigating literacy in blended learning environments. The purpose of this research study focused on addressing a gap in the current literature in these specific areas to investigate the relationship between ELA teachers’ pedagogical practices and elements of secondary students’ learning motivation for ELA. Specifically, this study explored secondary ELA students’ perception of teachers’ classroom practices, self-regulated learning, and digital self-efficacy. The overarching research question in this study examined: What relationship exists between (a) the pedagogical practices of secondary ELA …

Identifying Nutrient Dynamics And Relative Groundwater Contribution In Wetlands At Fish Lake Environmental Center, Lapeer Mi, Rose Allen

Senior Honors Theses and Projects

Wetlands are complex ecosystems that are dependent on hydrologic processes and water chemistry. Understanding the role that water chemistry and nutrients play in wetland ecosystems is crucial to wetland management and restoration. The Fish Lake Environmental Education Center near Lapeer Michigan, is glacially influenced, and contains a large bog. Between the bog and lake there are multiple kettles that contain ephemeral wetlands in the spring. Bogs are primarily precipitation sourced, whereas the kettle wetlands may be a combination of precipitation and groundwater sourced. Previous studies indicated that groundwater flow direction is towards Fish Lake, but it was unclear to what …

Gerontovis: Data Visualization At The Confluence Of Aging, Zack While, R. Jordan Crouser, Ali Sarvghad

Computer Science: Faculty Publications

Despite the explosive growth of the aging population worldwide, older adults have been largely overlooked by visualization research. This paper is a critical reflection on the underrepresentation of older adults in visualization research. We discuss why investigating visualization at the intersection of aging matters, why older adults may have been omitted from sample populations in visualization research, how aging may affect visualization use, and how this differs from traditional accessibility research. To encourage further discussion and novel scholarship in this area, we introduce GerontoVis, a term which encapsulates research and practice of data visualization design that primarily focuses on older …