Digital Commons Network^™

February 2024, Robert Kelly

Robert Kelly Manuscripts

No abstract provided.

Ipulse: February 2024, Lynn University

Student Newspapers

Issues:

• February 2024 [Spring Week #1]: Bigger Than Sports Lobs Donation from Pickleball Event: Bigger Than Sports Continues to Raise Money for Student Athletes; It’s the Real Dill: Lynn Students Are Fascinated by Pickleball; The Spectacular Journey of Lynn Cross Country Team: A Deep Dive into Lynn’s Cross Country; Meet Me at the Club: Lynn Students Promote Their Club; Dance Your Heart Out: The 8 Dance Team and the Founders of Lynn’s K-Pop Club; Get into the Groove: Record Shop Owners Discuss How They Started Their Business; What Does Trump Want with Greenland? What the U.S Would Gain by Acquiring …

"Crowd-Energizing Mission": A Utc Mascot Retrospective, Noah Lasley

Special Collections Exhibition Records and Catalogs

No abstract provided.

Autonomy And Free Thought In Brain- Computer Interactions: Review Of Legal Precedent For Precautionary Regulation Of Consumer Products, Sadia Khan, Daniel Cole, Hamid Ekbia

UC Law Science and Technology Journal

The expanding use of neurotechnologies in consumer products increases the risks to human rights such as autonomy and free thought. While potentially beneficial in clinical applications, technologies such as brain implants and EEG-enabled wearable devices pose serious concerns about mental and psychological manipulation of human beings. In the US in particular, law and policy are lagging behind technical developments, thereby increasing the risks of abuse and misuse from commercial neurotechnologies. This article focuses on commercial neurotechnologies, which are distinct from medical neurotechnologies for clinical diagnoses, and seeks to guard against human rights risks to users by overcoming that regulatory gap. …

The Spirit Of Mathematical Modeling – A Philosophical Study On The Occasion Of 50 Years Of Mathematical Modeling Education, Peter Frejd, Pauline Vos

The Mathematics Enthusiast

We mark the 50th anniversary of mathematical modeling education by reviving the term the spirit of mathematical modeling (SoMM), which idealistically reflects core aspects of mathematical modeling. The basis of our analysis is the notion of bildung, which is an educational philosophy that strives for harmonizing heart, mind, social life and culture. We built SoMM on five descriptions of mathematical modeling: two research studies from the 1970s, two studies about the work of professional modelers, and one about an environmental school project. We captured SoMM as a collection of aspects at the micro, meso and macro level: at the micro …

A Design Thinking Mixed Methods Study On Learned Empathy Through Multicultural Education, Samanantha Webb

Dissertations

The dissertation in practice focused on addressing the issue of inadequate diversity, equity, and inclusion (DEI) competencies among teachers in a Title I school. The problem of practice emerged within the context of an increasingly diverse educational landscape, necessitating educators to possess robust DEI skills. The proposed solution was a professional development (PD) program, crafted using a design thinking approach, which included an asynchronous learning module supplemented by a book study. The comprehensive PD program was aimed at enhancing the teachers' understanding and application of DEI principles, making the prototype relevant to the demands of multicultural education in today’s diverse …

The Trucking Industry, Working From Home, Covid-19, And Positive Social Change Effects, Martin Lulgjuraj

Walden Dissertations and Doctoral Studies

No abstract provided.

Mathematical Model Of Oxygen, Nutrient, And Drug Transport In Tuberculosis Granulomas, Meenal Datta, Mccarthy Kennedy, Saeed Siri, Laura Via, James W. Baish, Lei Xu, Veronique Dartois, Clifton Barry, Rakesh Jain

Faculty Journal Articles

Physiological abnormalities in pulmonary granulomas–pathological hallmarks of tuberculosis (TB)–compromise the transport of oxygen, nutrients, and drugs. In prior studies, we demonstrated mathematically and experimentally that hypoxia and necrosis emerge in the granuloma microenvironment (GME) as a direct result of limited oxygen availability. Building on our initial model of avascular oxygen diffusion, here we explore additional aspects of oxy- gen transport, including the roles of granuloma vasculature, transcapillary transport, plasma dilution, and interstitial convection, followed by cellular metabolism. Approximate analytical solutions are provided for oxygen and glucose concentration, interstitial fluid velocity, interstitial fluid pressure, and the thickness of the convective zone. …

From Canonical Law To Offshore Finance: Confessing To Priests And Bankers In Luxembourg, Samuel Weeks

College of Humanities and Sciences Faculty Papers

In this article, I address two recurring tendencies that I heard during a recent period of research on banking secrecy in Luxembourg. First, my banker interviewees frequently mentioned personal transgressions for why many of their clients hide assets “offshore.” The wrongdoings my interlocutors cited included not only clients’ tax evasion, bankruptcy, and avoidance of liability – but also divorce, adultery, and the existence of out-of-wedlock children. Second, with a similar frequency, my interviewees drew parallels between the secrecy laws covering bankers and those afforded to other professionals in the country. Article 458 of Luxembourg’s Penal Code, dating from the nineteenth …

Forage News [2024-02], University Of Kentucky

Forage News

No abstract provided.

Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume Three, Carolyn A. Ristau

eBooks

In this three-volume biography, we revisit the life and accomplishments of the revolutionary scientist, Donald R. Griffin. He encountered a lifetime of initial hostile resistance to his ideas and studies; now they are largely accepted. He and a colleague discovered the phenomenon of echolocation used by bats to navigate and capture insects, proposed that birds navigate guided by such cues as the sun and stars, and suggested that animals are likely aware, thinking and feeling beings. Forty interviews with his colleagues and friends help us understand the young emerging scientist and the mature researcher. We learn about his and others’ …

Phenotypic Similarity-Based Approach For Variant Prioritization For Unsolved Rare Disease: A Preliminary Methodological Report., David Lagorce, Emeline Lebreton, Leslie Matalonga, Oscar Hongnat, Maroua Chahdil, Davide Piscia, Ida Paramonov, Kornelia Ellwanger, Sebastian Köhler, Peter N Robinson, Holm Graessner, Sergi Beltran, Caterina Lucano, Marc Hanauer, Ana Rath

Faculty Research 2024

Rare diseases (RD) have a prevalence of not more than 1/2000 persons in the European population, and are characterised by the difficulty experienced in obtaining a correct and timely diagnosis. According to Orphanet, 72.5% of RD have a genetic origin although 35% of them do not yet have an identified causative gene. A significant proportion of patients suspected to have a genetic RD receive an inconclusive exome/genome sequencing. Working towards the International Rare Diseases Research Consortium (IRDiRC)'s goal for 2027 to ensure that all people living with a RD receive a diagnosis within one year of coming to medical attention, …

Astaxanthin And Meclizine Extend Lifespan In Um-Het3 Male Mice; Fisetin, Sg1002 (Hydrogen Sulfide Donor), Dimethyl Fumarate, Mycophenolic Acid, And 4-Phenylbutyrate Do Not Significantly Affect Lifespan In Either Sex At The Doses And Schedules Used., David E Harrison, Randy Strong, Peter C. Reifsnyder, Nadia Rosenthal, Ron Korstanje, Elizabeth Fernandez, Kevin Flurkey, Brett C Ginsburg, Meredith D Murrell, Martin A Javors, Marisa Lopez-Cruzan, James F Nelson, Bradley J Willcox, Richard Allsopp, David M Watumull, David G Watumull, Gino Cortopassi, James L Kirkland, Tamar Tchkonia, Young Geun Choi, Matthew J Yousefzadeh, Paul D Robbins, James R Mitchell, Murat Acar, Ethan A Sarnoski, Michael R Bene, Adam Salmon, Navasuja Kumar, Richard A Miller

Faculty Research 2024

In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2 activator astaxanthin (Asta) extended the median male lifespan by 12% (p = 0.003, log-rank test), while meclizine (Mec), an mTORC1 inhibitor, extended the male lifespan by 8% (p = 0.03). Asta was fed at 1840 ± 520 (9) ppm and Mec at 544 ± 48 (9) ppm, stated as mean ± SE (n) of independent diet preparations. Both were started at 12 months of age. The 90th percentile lifespan for both treatments was extended in absolute value by 6% in males, but neither was significant by …

Effect Of Different Molecular Weight Hyaluronic Acids On Skim Milk Functional Properties, Rutvi Joshi, Suresh G. Sutariya, Prafulla Salunke

Dairy Science and Food Science Faculty Publications: 2022 to Present

Hyaluronic acid (HA), a naturally occurring polysaccharide with recognized health benefits, has gained approval for use in the food industry as a food additive, ingredient, and health supplement in numerous countries. HA can increase viscosity in solutions and is available commercially in various molecular weights (MW) depending on end applications. Nevertheless, no research has explored the impact of different MW HAs on functionality, rheological properties, and texture-building benefits in the dairy product matrix wherein they are incorporated. Therefore, the objective of this study was to evaluate how varying MWs of HA—specifically 8 kDa, 320 kDa, 980 kDa, and 2550 kDa …

Preferential Binding Of Polyphenols In Blackcurrant Extracts With Milk Proteins And The Effects On The Bioaccessibility And Antioxidant Activity Of Polyphenols, Ting Mao, Fnu Akshit, Iresha Matiwalage, Subha Sasidharan, Caren Meyn Alvarez, Philip Wescombe, Maneesha S. Mohan

Dairy Science and Food Science Faculty Publications: 2022 to Present

Milk proteins are well-known delivery agents; however, there is no clear understanding of the competitive interactions of milk proteins with polyphenols in mixed complex systems. Here, we investigate the preferential competitive interactions of different polyphenols present in blackcurrant extract with milk proteins by quantifying the protein-bound polyphenols and comparing the factors affecting these interactions. In addition, bioaccessibility and antioxidant activity were studied after in vitro gastric digestion. Our results indicated that polyphenols from blackcurrant extracts were preferentially bound to caseins more than whey proteins, with noncovalent interactions causing secondary structural changes in the protein. The hydrophobicity and the charge of …

Plant Protein Flavor Chemistry Fundamentals And Techniques To Mitigate Undesirable Flavors, Serap Vatansever, Bingcan Chen, Clifford Hall

Dairy Science and Food Science Faculty Publications: 2022 to Present

Many plant protein ingredients have unpleasant flavor (e.g., green, beany, bitterness) characteristics. Isolation of the protein fraction will reduce the intensity of the undesirable flavors but in most cases the flavor issue is not eliminated. The objective of this review is to provide information about undesirable flavors associated with plant proteins and approaches to mitigate these flavors. The focus of the review will be on flavor associated with plant proteins from pulses, soybean, and oilseeds (e.g., hempseed, flaxseed). While other plant proteins exist, they will not be covered extensively in this limited review. The undesirable flavors are defined as volatile …

Art Teams Year 2 Report, Guy Trainin, Hyeonjin Yoon, Libby Valerio-Boster, Kimberley D'Adamo

Research and Evaluation in Education, Technology, Art, and Design

The Art TEAMS Year 2 Report outlines the progress and achievements of a grant-funded teacher professional learning initiative in art education. Focusing on integrating visual and emerging media arts into various subjects, the project has significantly surpassed its goals, evidencing its success through both qualitative and quantitative assessments. The wide-ranging engagement from educators across different settings underscores the initiative's effectiveness and its role in fostering a vibrant community committed to excellence in art education.

The curriculum developed for teacher professional development spans 8 graduate-level classes, focusing on pedagogy and emerging media arts, and is supported by a dedicated website for …

Without, Linda Caradine

The Lindenwood Review: a journal of literary prose

No abstract provided.

Contributors

The Lindenwood Review: a journal of literary prose

No abstract provided.

Keeping The Perpetual In Florida's Conservation Easements, Nancy Mclaughlin

Utah Law Faculty Scholarship

Hundreds of millions of dollars are being invested in the protection of the Florida Wildlife Corridor and other environmentally sensitive lands. One of the primary tools being used to accomplish this protection is the perpetual conservation easement, which is touted to landowners and the public as providing a permanent guarantee that the subject lands will never be developed. There is a very real danger, however, that perpetual conservation easements in Florida may not, in fact, be perpetual, and that the protections put in place today will vanish over time—along with the public funds invested therein—as government and nonprofit holders “release” …

The Fetterman Massacre: A Swiss American Officer Leads His Men To Disaster, Albert Winkler

Swiss American Historical Society Review

Following the American Civil War, the United States fought a major war against the Sioux, Cheyenne, and Arapaho Indians known as Red Cloud’s War, which lasted from 1866 to 1868. It was a costly American defeat and an important Indian victory. A prominent leader of the Native Americans was the great war chief, Red Cloud, who engineered much of their success. The conflict included many raids, skirmishes, and three important and bloody engagements including the Hayfield and the Wagon Box Battles in 1867, and the highly significant Fetterman Massacre in 1866 in which the Swiss American Captain, William J. Fetterman, …

Transcriptional And Functional Consequences Of Oncostatin M Signaling On Young Dnmt3a-Mutant Hematopoietic Stem Cells., Logan S Schwartz, Kira Young, Timothy M Stearns, Nathan Boyer, Kristina D Mujica, Jennifer J. Trowbridge

Faculty Research 2024

Age-associated clonal hematopoiesis (CH) occurs due to somatic mutations accrued in hematopoietic stem cells (HSCs) that confer a selective growth advantage in the context of aging. The mechanisms by which CH-mutant HSCs gain this advantage with aging are not comprehensively understood. Using unbiased transcriptomic approaches, we identified Oncostatin M (OSM) signaling as a candidate contributor to age-related Dnmt3a-mutant CH. We found that Dnmt3a-mutant HSCs from young adult mice (3-6 months old) subjected to acute OSM stimulation do not demonstrate altered proliferation, apoptosis, hematopoietic engraftment, or myeloid differentiation. Dnmt3a-mutant HSCs from young mice do transcriptionally upregulate an inflammatory cytokine network in …

Genetic Context Drives Age-Related Disparities In Synaptic Maintenance And Structure Across Cortical And Hippocampal Neuronal Circuits., Sarah E Heuer, Emily W Nickerson, Gareth R Howell, Erik B Bloss

Faculty Research 2024

The disconnection of neuronal circuitry through synaptic loss is presumed to be a major driver of age-related cognitive decline. Age-related cognitive decline is heterogeneous, yet whether genetic mechanisms differentiate successful from unsuccessful cognitive decline through maintenance or vulnerability of synaptic connections remains unknown. Previous work using rodent and primate models leveraged various techniques to imply that age-related synaptic loss is widespread on pyramidal cells in prefrontal cortex (PFC) circuits but absent on those in area CA1 of the hippocampus. Here, we examined the effect of aging on synapses on projection neurons forming a hippocampal-cortico-thalamic circuit important for spatial working memory …

Wash-O-Rama, Jason Vrabel

The Lindenwood Review: a journal of literary prose

No abstract provided.

2024-02-01 Caudill Connection, Morehead State University. Caudill College Of Arts, Humanities And Social Sciences.

Caudill Connection

Caudill Connection newsletter for February of 2024.

Sarin-Induced Neuroinflammation In Mouse Brain Is Attenuated By The Caspase Inhibitor Q-Vd-Oph, Ekta J. Shah, William C. Grunwald Jr., Teresa L. Garrett, Thomas L. Brown, David R. Cool

Neuroscience, Cell Biology & Physiology Faculty Publications

Organophosphates cause hyperstimulation of the central nervous system, leading to extended seizures, convulsions, and brain damage. Sarin is a highly toxic organophosphate nerve agent that has been employed in several terrorist attacks. The prolonged toxicity of sarin may be enhanced by the neuroinflammatory response initiated by the inflammasome, caspase involvement, and generation/release of proinflammatory cytokines. Since neurodegeneration and neuroinflammation are prevalent in sarin-exposed animals, we were interested in evaluating the capacity of quinolyl-valyl-O-methylaspartyl-[-2,6-difluorophenoxy]-methyl ketone (Q-VD-OPh), a pan caspase inhibitor to attenuate neuroinflammation following sarin exposure. To test this hypothesis, sarin-exposed C57BL/6 mice were treated with Q-VD-OPh or negative control quinolyl-valyl-O-methylglutamyl-[-2,6-difluorophenoxy]-methyl …

The Comment, February 1, 2024, Bridgewater State University

The Comment

No abstract provided.

The Utah English Journal, Volume 52, 2024: Full Issue, The Utah English Journal

The Utah English Journal

No abstract provided.

Library News February 2024, Research Medical Library

Library News 2024

• Tips and Tricks for Identifying Predatory Journals
• The Fair Use Doctrine: When and How You Can Use Copyrighted Material
• Library Staff-Contributed Publications 2023
• Chat with a Librarian
• The Final Word on Sacrificed, Killed, or Euthanized

The Impact Of Adding Hops To Alfalfa At Different Rates On Silage Quality And Methane Emissions In Vitro, Erdem Gülümser, Hani̇fe Mut, Eki̇n Sucu, Uğur Başaran, Medi̇ne Çopur Doğrusöz

Turkish Journal of Agriculture and Forestry

Legumes are typically challenging to ensile due to their low concentration of water-soluble carbohydrates and high capacity for buffering. If legumes and medicinal plants are ensiled together, the silage quality increases, which benefits the digestive system of ruminates. The aim of this study was to research the effects of different alfalfa (Medicago sativa L.) and hops (Humulus lupulus L.) ratios on silage quality and in vitro rumen fermentation traits. The plant materials were chopped to a particle size of <2 cm; then alfalfa (A) and hops (H) were ensiled in ratios of 100A + 0H, 75A + 25H, 50A + 50H, 25A + 75H and 0A + 100H by weight with 4 replicates. Fresh silage samples were left to ferment for 45 days at 25 ± 2 °C. Subsequently, it was observed that hops added to alfalfa improved the silage’s fermentation qualities. At a 75A + 25H ratio, the silage quality increased due to having a lower pH and dry matter ratio as well as increased values for Flieg score, crude protein, relative feed, and condensed tannin concentration. A higher proportion of alfalfa in the silage mixture increased methane (CH4) and carbon dioxide (CO2) and decreased lactic acid (LA). Comparing 50A + 50H and 25A + 75H silages to 100A + 0H, the CH4 production was 26.19% and 27.80% lower, respectively, and the CO2 production decreased by 25.61% and 28.15%, respectively. Consequently, the 50A + 50H and 25A + 75H silage ratios are advised for feeding ruminants. Furthermore, more research with different forage combinations is required to understand how hops influence rumen fermentation.