Digital Commons Network^™

Broken Pieces: An Accident That Felt Destined, Despite Every Effort To Avoid Complacency, Stacy Boone

Appalachia

An experienced guide’s solo thru-hike of the Oregon Desert Trail ends suddenly with a broken knee and a courageous self-rescue.

Appalachia Winter/Spring 2024: Complete Issue

Appalachia

Winter/Spring 2024 - Volume LXXV, Number 1 - Issue #257. Engines of Extremes: Stories of pushing beyond previous limits.

Civil Rights Nondiscrimination Information For Local Public Agencies, Taffanee Keys

Purdue Road School

This session will discuss new ADA/Title VI.

Compressed Natural Gas And How It Works, Ryan Lisek

Purdue Road School

Join us for a discussion about compressed natural gas (CNG) and how it works. Attendees will learn safety measures, where CNG works and where it doesn’t, cost and operation comparisons, fuel efficiency, infrastructure, emissions, and garage modifications.

Tolkien: Uomo, Professore, Autore (2023), Ivano Sassanelli

Journal of Tolkien Research

Book review, by Ivano Sassanelli, of Tolkien: Uomo, Professore, Autore (2023)

Deep Learning-Based Predictive Classification Of Functional Subpopulations Of Hematopoietic Stem Cells And Multipotent Progenitors., Shen Wang, Jianzhong Han, Jingru Huang, Khayrul Islam, Yuheng Shi, Yuyuan Zhou, Dongwook Kim, Jane Zhou, Zhaorui Lian, Yaling Liu, Jian Huang

Cooper Medical School of Rowan University Departmental Research

BACKGROUND: Hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) play a pivotal role in maintaining lifelong hematopoiesis. The distinction between stem cells and other progenitors, as well as the assessment of their functions, has long been a central focus in stem cell research. In recent years, deep learning has emerged as a powerful tool for cell image analysis and classification/prediction.

METHODS: In this study, we explored the feasibility of employing deep learning techniques to differentiate murine HSCs and MPPs based solely on their morphology, as observed through light microscopy (DIC) images.

RESULTS: After rigorous training and validation using extensive image …

March 13, 2024, Csusb

Coyote Chronicle (1984-)

No abstract provided.

Blue Moon: Exploring The Complexities Of Human Love Through A Werewolf Romance Novel, Kayla Lafroth

Undergraduate Honors Theses

Blue Moon is a werewolf romance novel that emphasizes the heartbreak and triumph of human love through a cast of non-human characters. This story is written to explore the complexities of love, acting as an intersection between werewolves and romantic tragedy. In Blue Moon, Luna’s perfect world comes crashing down when her soulmate, Aspen, rejects her as his mate, something unheard of in werewolf culture. In a desperate attempt to win his affection, Luna feigns a soulmate bond with Kodiak, an alpha werewolf who is looked down upon for having no mate. As the layers of Luna’s relationship with …

Spartan Daily, March 13, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 162, Issue 21

The Role Of Age, Sex, And Mglur5 Receptors In Hippocampal Depotentiation In Mice, Michael Dew

Undergraduate Honors Theses

Synaptic plasticity of excitatory hippocampal circuits is one of the primary cellular mechanisms of learning and memory. Synaptic plasticity is also implicated in many disease states such as depression, post-traumatic stress disorder, and Alzheimer disease. Long-term potentiation (LTP) is the plastic strengthening of synapses, while long-term depression (LTD) is the weakening of synapses. Depotentiation is the process of reversing previously established long-term potentiation. Depotentiation has not been studied as thoroughly as long-term potentiation and long-term depression. We examined the role of age, metabotropic glutamate receptor 5 (mGluR5), and sex in the process of CA1 hippocampal depotentiation in young CD-1 mice …

Multispecies Comparative Prostate Anatomy By Imaging: Implications For Experimental Models Of Prostatic Disease, Felipe M. Berg, Eduardo T.O. Correia, Eric C. Abenojar, James P. Basilion, Agata A. Exner, Leonardo K. Bittencourt

Faculty Scholarship

Background: There is an increasing interest in using preclinical models for development and assessment of medical devices and imaging techniques for prostatic disease care. Still, a comprehensive assessment of the prostate's radiological anatomy in primary preclinical models such as dogs, rabbits, and mice utilizing human anatomy as a reference point remains necessary with no optimal model for each purpose being clearly defined in the literature. Therefore, this study compares the anatomical characteristics of different animal models to the human prostatic gland from the imaging perspective. Methods: We imaged five Beagle laboratory dogs, five New Zealand White rabbits, and five mice, …

Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep L.X. Vu, David Scott Mcvey

Department of Animal Science: Faculty Publications

African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security. Extensive efforts have been directed toward developing effective ASF vaccines. Among the vaccinology approaches tested to date, liveattenuated virus (LAV) vaccines produced by rational deleting virulence genes from virulent African Swine Fever Virus (ASFV) strains have demonstrated promising safety and efficacy in experimental and field conditions. Many gene-deleted LAV vaccine candidates have been generated in recent years. The virulence genes targeted for deletion from …

Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep Vu, David Scott Mcvey

Department of Animal Science: Faculty Publications

African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security. Extensive efforts have been directed toward developing effective ASF vaccines. Among the vaccinology approaches tested to date, liveattenuated virus (LAV) vaccines produced by rational deleting virulence genes from virulent African Swine Fever Virus (ASFV) strains have demonstrated promising safety and efficacy in experimental and field conditions. Many gene-deleted LAV vaccine candidates have been generated in recent years. The virulence genes targeted for deletion from …

Spectrum, Volume 52, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Controversial IVF Law in Alabama Raises Questions on Reproductive Freedom - Inside SHU’s Faculty Peer Coaching Program - Faculty Peer Coaching Program - A Look Into The Music Education Program - Multicultural Center Wisdom Wednesdays - The Comfort of Stuffed Animals for College Students - Professor Produces New Film Featuring Students

Predicting Gender Of Author Using Large Language Models (Llms), Satya Uday Sanku

USF Tampa Graduate Theses and Dissertations

The advent of text data from social media, blogs, movie reviews, and other textual sources has opened new avenues for research, particularly in the domain of Author Profiling. Author Profiling helps in Capturing the Stylistic features and also useful for analyzing the required elements in the written text. This Study addresses one of the tasks in Author Profiling which is termed as gender detection or Classification of Gender from Text. The main goal of this research is to obtain valuable and relevant gender characteristics that will accurately classify the Author’s gender of a review extracted from an Anime Review website. …

March 13, 2024 (Vol. 108, No. 23), Daily Eastern News

Daily Eastern News: 2023-2024

No abstract provided.

2024 Nebraska Farmland Values And Cash Rental Rates, Jim Jansen, Jeffrey Stokes

Cornhusker Economics

The market value of agricultural land in Nebraska increased by 5% over the prior year to an average of $4,015 per acre, according to the 2024 Nebraska Farm Real Estate Market Survey. This marks the third consecutive year of increases in the market value of agricultural land in Nebraska, setting another high in the non-inflation-adjusted statewide land value in the survey's 46-year history.

An Exposome Atlas Of Serum Reveals The Risk Of Chronic Diseases In The Chinese Population, Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu

Faculty, Staff and Student Publications

Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we collected serum samples from 5696 healthy people and patients, including those with 12 chronic diseases, in China and completed serum biomonitoring including 267 chemicals via gas and liquid chromatography-tandem mass spectrometry. Seventy-four highly frequently detected exposures were used for exposure characterization and risk analysis. The results show that region is the most critical factor influencing human exposure levels, followed by age. Organochlorine pesticides and perfluoroalkyl substances are associated with multiple chronic diseases, …

Geography, Climate, And Habitat Shape The Microbiome Of The Endangered Rock Gnome Lichen (Cetradonia Linearis), Julianna Paulsen, Jessica L. Allen, Nathan Morris, Jenna Dorey, Jenifer B. Walke, S. Elizabeth Alter

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Bacterial symbionts are essential components of healthy biological systems. They are increasingly recognized as important factors in the study and management of threatened species and ecosystems. Despite management shifts at the ecosystem level, microbial communities are often neglected in discussions of holobiont conservation in favor of the primary members of a symbiosis. In this study, we addressed the bacterial community knowledge gap for one of two federally endangered lichen species in the United States, Cetradonia linearis (Cladoniaceae). We collected 28 samples of the endangered rock gnome lichen (Cetradonia linearis) from 13 sites and characterized bacterial communities in thalli using 16S …

From Displacement To Intersubjectivity: A Phenomenology Of Sound In Classic Film Noir, Thomas Goodchild

USF Tampa Graduate Theses and Dissertations

This paper analyzes the use of sounds displaced from their sources in classic filmsnoir. Noir is often understood as a dark and solipsistic moment in American cinema. Interpretations of noir frequently emphasize isolated individuals who are physically, psychologically, and socially displaced from their environments. Although scholarship on noir has examined this alienation through various sonic motifs such as music and voice-over, I investigate how several noirs draw attention to the act of listening through acousmatic sound—that is, sound heard without a visible source. Far from being an ephemeral auditory experience, I argue that the separation between sound and image invites …

“The History Of Every Country Begins In The Heart Of A…Woman”: Willa Cather’S Reclamation Of The Female American Immigrant Through Edenic Western Narratives, Emma Fox

Undergraduate Honors Theses

This thesis analyzes Willa Cather’s Great Plains Trilogy—O, Pioneers! (1913), The Song of the Lark (1915), and My Ántonia (1918)—in the context of the immigration boom of the early 1900s and the myth of an “American Eden.” This concept was born of cultural portrayals of the West as dominated by white, male pioneers who subdued the landscape, but Cather’s novels, centered around immigrant families, significantly revise this popular myth. Nativists saw the West as the source of American virtues such as democracy and diligence and viewed sending immigrants West as an essential tool for “Americanization,” the process by which …

Facile Synthesis Of Fe2o3, Fe2o3@ Cuo And Wo3 Nanoparticles: Characterization, Structure Determination And Evaluation Of Their Biological Activity, Asmaa Taha

Nanotechnology Research Centre

Due to their high specific surface area and its characteristic’s functionalized nanomaterials have great potential in medical applications specialty, as an anticancer. Herein, functional nanoparticles (NPs) based on iron oxide Fe2O3, iron oxide modified with copper oxide Fe2O3@ CuO, and tungsten oxide WO3 were facile synthesized for biomedical applications. The obtained nanomaterials have nanocrystal sizes of 35.5 nm for Fe2O3, 7 nm for Fe2O3@ CuO, and 25.5 nm for WO3. In addition to octahedral and square nanoplates for Fe2O3, and WO3; respectively. Results revealed that Fe2O3, Fe2O3@ CuO, and WO3 NPs showed remarked anticancer effects versus a safe effect on …

The Identification Of Small Molecule Inhibitors With Anthelmintic Activities That Target Conserved Proteins Among Ruminant Gastrointestinal Nematodes, Hyeim Jung, Dante Zarlenga, John C Martin, Peter Geldhof, Kymberlie Hallsworth-Pepin, Makedonka Mitreva

2020-Current year OA Pubs

Gastrointestinal nematode (GIN) infections are a major concern for the ruminant industry worldwide and result in significant production losses. Naturally occurring polyparasitism and increasing drug resistance that potentiate disease outcomes are observed among the most prevalent GINs of veterinary importance. Within the five major taxonomic clades, clade Va represents a group of GINs that predominantly affect the abomasum or small intestine of ruminants. However, the development of effective broad-spectrum anthelmintics against ruminant clade Va GINs has been challenged by a lack of comprehensive druggable genome resources. Here, we first assembled draft genomes for three clade Va species (

Retrospective Evaluation Of Penguin Cold Caps For Chemotherapy-Induced Alopecia., Dale Weaver, Michelle L Pershing, Bethany Golden, Laura Hammel, Pauline Kefalas Russ, Mark Cripe

Oncology Articles

BACKGROUND: Scalp cooling is an increasingly recognized non-pharmacologic approach to minimize chemotherapy-induced alopecia (CIA). Several commercially available machine-based and manual scalp cooling systems are available; however, literature reports of effectiveness are highly variable. The purpose of this study was to determine real-world tolerability and subjective effectiveness of a manual cold capping system in minimizing CIA across a variety of patient race and hair types. This study was a single-institution review of outcomes from manual cold capping.

METHODS: We identified retrospective cohort of adult patients who presented to discuss cold capping between January 14, 2019, and March 31, 2022. Data collected …

Office Of Research, Economic Engagement And Outreach Update, March 13, 2024, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Health Status In An Urban-Dwelling, Subtropical Frog Species (Lithobates Sphenocephalus) And Its Relation To Ranavirus And Hemoparasites, Gabrielle M. Wickersham

USF Tampa Graduate Theses and Dissertations

Urbanization poses significant challenges to wildlife, including amphibians. The present study uses a multi-parameter approach that incorporates veterinary techniques to investigate the current health status of the adult southern leopard frogs (Lithobates sphenocephalus) in Tampa Bay, Florida, amidst urban stressors including nutrient loading, fragmented habitats, and light and noise pollution. Novel values for fluctuating asymmetry (e.g., variation between left and right bilateral traits; FA), body condition (CF), stress (e.g., neutrophil:lymphocyte (N:L) ratio), and inflammation (e.g., neutrophil morphologic abnormalities, parasite load) are reported. I also investigate the relationship of overall health with ranavirus presence and hemoparasite infections. Ranavirus was absent in …

Explaining Optimisation Of Offshore Wind Farms Using Metaheuristics, M Walter, P Manikowski, M Craven, D Walker

School of Engineering, Computing and Mathematics

No abstract provided.

Microcurrent-Mediated Modulation Of Myofibroblasts For Cardiac Repair And Regeneration, Dipthi Bachamanda Somesh, Karsten Jürchott, Thomas Giesel, Thomas Töllner, Alexander Prehn, Jan-Peter Richters, Dragana Kosevic, J. Eduardo Rame, Peter Göttel, Johannes Müller

Division of Cardiology Faculty Papers

Cardiovascular diseases are a significant cause of illness and death worldwide, often resulting in myofibroblast differentiation, pathological remodeling, and fibrosis, characterized by excessive extracellular matrix protein deposition. Treatment options for cardiac fibrosis that can effectively target myofibroblast activation and ECM deposition are limited, necessitating an unmet need for new therapeutic approaches. In recent years, microcurrent therapy has demonstrated promising therapeutic effects, showcasing its translational potential in cardiac care. This study therefore sought to investigate the effects of microcurrent therapy on cardiac myofibroblasts, aiming to unravel its potential as a treatment for cardiac fibrosis and heart failure. The experimental design involved …

Roles Of Bryophytes In Forest Sustainability—Positive Or Negative?, Janice M. Glime

Michigan Tech Publications

Bryophytes were traditionally ignored in most studies of forest ecosystem processes, or they were included with litter or soil. In the last few decades we have begun to understand their many roles that permit them to be ecosystem engineers. This review serves to pull together many scattered sources into a single source on the many contributions bryophytes can perform as ecosystem engineers and to support what several authors have already stressed: that bryophytes should not be treated as a single functional group. It puts bryophytes in perspective in terms of richness and biomass, then explores their roles as ecosystem engineers; …

Short Cell Cycle Duration Is A Phenotype Of Human Epidermal Stem Cells, Tong Xiao, Ugomma C Eze, Alex Charruyer-Reinwald, Tracy Weisenberger, Ayman Khalifa, Brook Abegaze, Gabrielle K Schwab, Rasha H Elsabagh, T Richard Parenteau, Karl Kochanowski, Merisa Piper, Yumin Xia, Jeffrey B Cheng, Raymond J Cho, Ruby Ghadially

Staff and Researcher Publications

Background: A traditional view is that stem cells (SCs) divide slowly. Meanwhile, both embryonic and pluripotent SCs display a shorter cell cycle duration (CCD) in comparison to more committed progenitors (CPs).

Methods: We examined the in vitro proliferation and cycling behavior of somatic adult human cells using live cell imaging of passage zero keratinocytes and single-cell RNA sequencing.

Results: We found two populations of keratinocytes: those with short CCD and protracted near exponential growth, and those with long CCD and terminal differentiation. Applying the ergodic principle, the comparative numbers of cycling cells in S phase in an enriched population of …