Digital Commons Network^™

Dazzle Makes A Wish, Maria Medina

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.

Watercave: Virtual Reality For Engaging The Next Generation In Wastewater Management, Leeza Duller

Graduate Student and Postdoctoral Fellow Symposium

Within the next five to ten years, a significant portion of water and wastewater personnel are expected to retire, posing a substantial challenge for the utilities industry. The potential shortage of experienced workers poses inherent risks to the continuity of water services. WaterCAVE emerges as one of several tools designed to address this impending issue by engaging and inspiring the next generation to consider careers in the wastewater industry. This virtual reality (VR) simulation utilizes a ten-sided immersive display and was designed using Unity's 3D real-time development platform. Students from various educational levels, ranging from Pre-K to 12, are invited …

Vigilance And Foraging Behaviors Of Two Sciurid Species Between College Campuses And Urban Environments, Patrick Geyer, Zoe Buffington, Lorelei E. Patrick

SACAD: Scholarly Activities

A comparison between the extent that sciurid specimens display vigilance and foraging behaviors on college campuses against specimens within urban environments. Observations of fox squirrels and western gray squirrels were taken from the Squirrel-Net behavioral database used for this project. We found there was a significant difference between the percent vigilance behaviors and foraging behaviors on college campuses compared to urban environments. This suggests that squirrels residing on college campuses are more desensitized to pedestrian activity and foot traffic compared to squirrels that inhabit urban areas.

Generating Crispr Mutations In The Asymmetric Leaves1 Gene Of Arabidopsis, Gabriella J. Rueschhoff, Tara Phelps-Durr

SACAD: Scholarly Activities

The goal of this study is to create new mutations in the ASYMMETRIC LEAVES 1 (AS1) gene of Arabidopsis using CRISPR technology. AS1 is a myb domain transcription factor that represses the KNOX genes, a group of genes involved in maintaining an undifferentiated cell state. AS1 binds to the chromatin remodeling protein Histone Repressor A (HIRA). In animals, HIRA is involved in the permanent suppression of proliferation genes required for early development. The interaction between AS1 and HIRA provides clues to how AS1 maintains suppression at the KNOX genes; however, we must be careful applying what …

Opportunities For Maximizing The Dietary Quality Of Fad Diets, Jessica M. Phelan, Jill Joyce, Katherine Bode, Sara K. Rosenkranz

SACAD: Scholarly Activities

The quality of American diets, measured by the Healthy Eating Index (HEI), has remained stable and low since 2005. The Dietary Guidelines for Americans 2020–2025 call for research analyzing dietary patterns to determine how guidelines might be altered to increase healthy eating. The present paper seeks to determine the dietary quality of popular fad dietary patterns among Americans. A definition of “fad diet” was created, and Google Trends© was searched for popular diets to determine popular dietary patterns based on the fad diet definition. Finally, eight dietary patterns were identified for inclusion. One-week sample menus were created for each dietary …

Changing The Culture Of Secondary School Mathematics: What Are The Effects Of Interventions On Student Attitudes, Beliefs, And Motivation?, Meagan Coronado

Student Theses and Dissertations

In this study, 80 ninth-grade students enrolled in Algebra I from a high school in south Texas completed the Implicit Theories of Intelligence Scale for Children (ITIS) Survey and the Attitudes Toward Mathematics Inventory (ATMI) Survey, before and after a set of interventions. The students were divided into one of four groups, three with applied intervention and one control group: intelligence theory, utility value theory, both intelligence theory and utility value theory, and no interventions (control group). Analyses were conducted to determine the impact of the interventions on the overall scores on the ITIS and ATMI surveys. The results showed …

Ly6c+ Monocytes In The Skin Promote Systemic Alphavirus Dissemination, Autumn C Holmes, Cormac J Lucas, Morgan E Brisse, Brian C Ware, Heather D Hickman, Thomas E Morrison, Michael S Diamond

2020-Current year OA Pubs

Alphaviruses are mosquito-transmitted pathogens that induce high levels of viremia, which facilitates dissemination and vector transmission. One prevailing paradigm is that, after skin inoculation, alphavirus-infected resident dendritic cells migrate to the draining lymph node (DLN), facilitating further rounds of infection and dissemination. Here, we assess the contribution of infiltrating myeloid cells to alphavirus spread. We observe two phases of virus transport to the DLN, one that occurs starting at 1 h post infection and precedes viral replication, and a second that requires replication in the skin, enabling transit to the bloodstream. Depletion of Ly6C

Overcoming Bias In Standardized Testing, Paul Riebe

Masters Projects

The current state of education is one where student and teacher’s futures are dictated by the outcomes of standardized tests, which are inherently biased against students of color. The purpose of this project is to examine the bias in these tests to determine what exactly these biases are, and train teachers to better prepare their students to overcome these biases. For this project, I chose literature that examined the biases found in standardized testing through a number of different topics such as the effect on teacher attrition, the bias found in standardized testing, educational inequity and the meaning of intelligence. …

Animal Science News (March 26, 2024), Department Of Animal Science

Animal Science Newsletters

No abstract provided.

Cim211.2 Critical Analysis Example 3, Sae University College

Exemplars

An analysis of Arkham Asylum through a Mad Studies lens.

Development Of 3d Printed Anatomically Equivalent Thermoplastic Polyurethane Conduits For Peripheral Nerve Regeneration, Allen Zennifer M

Theses and Dissertations

Three-dimensional (3D) printing is an emerging tool for creating patient-specific tissue constructs analogous to the native tissue microarchitecture. In this study, anatomically equivalent 3D nerve conduits were developed using thermoplastic polyurethane (TPU) by combining reverse engineering and material extrusion (i.e., fused deposition modelling) technique.

Printing parameters were optimized to fabricate nerve-equivalent TPU constructs. The TPU constructs printed with different infill densities supported the adhesion, proliferation, and gene expression of neuronal cells. Subcutaneous implantation of the TPU constructs for three months in rats showed neovascularization with negligible local tissue inflammatory reactions and was classified as a non-irritant biomaterial as per ISO …

Grp94 Selective Inhibitors And Uses Thereof, Sanket Jaiprakash Mishra, Brian S. J. Blagg, Chad Anthony Dickey

USF Patents

The present technology provides compounds according to Formula I or Formula III as well as compositions including such compounds useful for the treatment of metastatic cancer and/or glaucoma.

The Myths Of Plato: Socratic Kenosis And The Call Of Beauty, Daniel Edward Shirley

Master of Arts in Classical Studies

The myths of Plato have been inordinately subordinated to the “intellect” of Plato since the eighteen-thirties. The ancient Christian tradition of interpreting stories and scriptures with symbolic understanding serves as a potentially primary hermeneutical pattern that could correct the modern tendency of subconscious materialism. To restore the Platonic myths, there are two foundational arguments to be made about the myths. The first is that these myths are kenotic in function. Observing the Socratic call to self-emptying, especially in the cosmological image of the World Axis, challenges modern assumptions concerning the second goodness of Platonic myth. The second argument is the …

The Transformation Of Social Work In Ukraine Before And During The War, Jaroslaw Richard Romaniuk, Kathleen J. Farkas

Faculty Scholarship

Background: This article aims to review the development of the social work profession in Ukraine and to describe the impact of social, economic and political changes on social work practices and education. Methods: A comprehensive literature review and participant observation methods informed this study. A case study of a Polish community’s response to Ukrainian war refugees illustrates how social workers might capitalize on current social structures to continue strengthening civil society in Ukraine. Findings and Discussion: Social Work, focusing on the fit between person and environment, is shaped by knowledge, culture and belief systems. Ukraine’s history and transition from communist/centralized …

The Impacts Of Nature-Based Sediment Restoration Practices On Coastal Wetland Soil Biogeochemistry, Jacob Z. Cheng

LSU Master's Theses

Coastal marshes provide many valuable ecosystem services. However, these wetlands are threatened worldwide, being subject to sea level rise, sediment starvation, subsidence, coastal edge erosion, etc. Many efforts are being made to counteract this wetland loss and preserve the ecosystem services. Two such methods are sediment diversion and the thin layer placement (TLP) of dredged sediment.

Sediment diversion involves reconnecting the main channel of a river body to disconnected wetlands, supplying much needed soil-building materials. However, this method affects the salinity of the waters, introducing large amounts of freshwater into the system. Salinity changes can affect marsh biogeochemistry. Most ecological …

Changes In Human Resources Function In Higher Education Institutions During A Pandemic, Naterena Anevia Parham-Cofield

Walden Dissertations and Doctoral Studies

No abstract provided.

Problem-Solving In The Preparation Of Teachers For Agricultural Education: A Mixed Methods Study Investigating The Effect Of Metacognitive Awareness And Cognitive Ability On Students Enrolled In An Introductory Agricultural Mechanics Course, Whitney Figland

LSU Doctoral Dissertations

Cognitive and metacognitive ability have been identified as a critical factor that influences individuals to successfully problem-solve. However, recent research has indicated that students do not have the necessary 21st-century skills to be successful in the workplace. This issue has been confounded by the lack of school-based agricultural education (SBAE) teachers’ limited knowledge regarding effectively teaching decision-making skills and the use of teaching methods that promote problem-solving. Therefore, this study sought to understand the effect that cognitive and metacognitive ability had on the problem-solving of students who are enrolled in an Introduction to Agricultural Mechanics course at Louisiana State University. …

Biological Significances Of Environmental Pollution In The New Calabar River, Southern Nigeria: A Case Study In Zooplankton Composition, Ibienebo Davies Imachrist, Francis David Sikoki, Philomina Kika, Davies Ibienebo Chris

Journal of Bioresource Management

The study was conducted for three months (May to July 2020), focusing on the physicochemical parameters and zooplankton composition in the Ogbogoro region of the New Calabar River in Nigeria. This investigation was carried out at three distinct monitoring stations. The physicochemical parameters were determined using standard ecological analytic procedures. PAST and SPSS were used for the statistical analysis. The temperature ranged between 26.5 to 33 ºC, salinity (1.23 to 1.86 %), pH (7.4 to 9.62), Total Dissolved Solids (2419 to 5,817 mg/L), conductivity (223.83 to 7,328 μS/cm), turbidity (3.415 to 15.05 NTU) and Dissolved Oxygen (3.8 to 6.8 mg/L). …

Biomarkers For Managing Neurodegenerative Diseases, Lara Cheslow, Adam E. Snook, Scott A. Waldman

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Neurological disorders are the leading cause of cognitive and physical disability worldwide, affecting 15% of the global population. Due to the demographics of aging, the prevalence of neurological disorders, including neurodegenerative diseases, will double over the next two decades. Unfortunately, while available therapies provide symptomatic relief for cognitive and motor impairment, there is an urgent unmet need to develop disease-modifying therapies that slow the rate of pathological progression. In that context, biomarkers could identify at-risk and prodromal patients, monitor disease progression, track responses to therapy, and parse the causality of molecular events to identify novel targets for further clinical investigation. …

Amino Acid Formula Induces Microbiota Dysbiosis And Depressive-Like Behavior In Mice, Ji Hu, Kaixin He, Yifei Yang, Chuan Huang, Yiping Dou, Hao Wang, Guorong Zhang, Jingyuan Wang, Chaoshi Niu, Guoqiang Bi, Lan Zhang, Shu Zhu

Faculty, Staff and Student Publications

Amino acid formula (AAF) is increasingly consumed in infants with cow's milk protein allergy; however, the long-term influences on health are less described. In this study, we established a mouse model by subjecting neonatal mice to an amino acid diet (AAD) to mimic the feeding regimen of infants on AAF. Surprisingly, AAD-fed mice exhibited dysbiotic microbiota and increased neuronal activity in both the intestine and brain, as well as gastrointestinal peristalsis disorders and depressive-like behavior. Furthermore, fecal microbiota transplantation from AAD-fed mice or AAF-fed infants to recipient mice led to elevated neuronal activations and exacerbated depressive-like behaviors compared to that …

Intergenerational Protective Anti-Gut Commensal Immunoglobulin G Originates In Early Life, Brigida Rusconi, Adina K Bard, Ryan Mcdonough, Angel M Kindsvogel, Jacqueline D Wang, Sreeram Udayan, Keely G Mcdonald, Rodney D Newberry, Phillip I Tarr

2020-Current year OA Pubs

Maternal immunoglobulins of the class G (IgGs) protect offspring from enteric infection, but when, where, and how these antibodies are physiologically generated and confer protection remains enigmatic. We found that circulating IgGs in adult mice preferentially bind early-life gut commensal bacteria over their own adult gut commensal bacteria. IgG-secreting plasma cells specific for early-life gut bacteria appear in the intestine soon after weaning, where they remain into adulthood. Manipulating exposure to gut bacteria or plasma cell development before, but not after, weaning reduced IgG-secreting plasma cells targeting early-life gut bacteria throughout life. Further, the development of this anti-gut commensal IgG …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Community-Centered Early Warning For Outbreaks In Humanitarian Emergencies: Evaluating Community-Based Surveillance For Priority Communicable Diseases Among Internally Displaced Populations In Iraq, Caitlin M. Wolfe

USF Tampa Graduate Theses and Dissertations

Background: Community based surveillance (CBS) is the organized and rapid collection of information from health events identified in the community and includes the systematic detection and reporting of events of public health significance. While used globally to enhance the detection of priority diseases, CBS has not been routinely deployed in Iraq, where a once-robust health system has been devastated by decades of war, international sanctions, and large-scale population displacement. During infectious disease outbreaks, it is imperative to quickly detect and isolate suspect cases, investigate confirmed cases, and trace and monitor the contacts of confirmed cases. The COVID-19 pandemic underscored the …

Author Correction: Cytoskeleton Remodeling Induced By Smyd2 Methyltransferase Drives Breast Cancer Metastasis, Alexandre G Casanova, Gael S Roth, Simone Hausmann, Xiaoyin Lu, Ludivine J M Bischoff, Emilie M Froeliger, Lucid Belmudes, Ekaterina Bourova-Flin, Natasha M Flores, Ana Morales Benitez, Tourkian Chasan, Marcello Caporicci, Jessica Vayr, Sandrine Blanchet, Francesco Ielasi, Sophie Rousseaux, Pierre Hainaut, Or Gozani, Muriel Le Romancer, Yohann Couté, Andres Palencia, Pawel K Mazur, Nicolas Reynoird

Faculty, Staff and Student Publications

No abstract provided.

The Wild, Wild West Of Laboratory Developed Tests, John Gilmore

Washington and Lee Law Review Online

Since the 1950’s, scientists have built novel technologies to screen for genetic diseases and other biological irregularities. Recently, researchers have developed a method called “liquid biopsy” (as opposed to a standard tissue biopsy) that uses a liquid sample (e.g., blood) to non‑invasively spot biomarkers indicating different types of cancers in the patient’s body. While the U.S. Food and Drug Administration (FDA) has fully cleared a small number of liquid biopsy tests under its rigorous and expensive review process, most biotech companies have instead followed a less restrictive regulatory path through the Centers for Medicare and Medicaid Services (CMS), which label …

A Therapeutically Targetable Positive Feedback Loop Between Nc-Hlx-2-7, Hlx, And Myc That Promotes Group 3 Medulloblastoma, Keisuke Katsushima, Kandarp Joshi, Menglang Yuan, Brigette Romero, Mona Batish, Stacie Stapleton, George Jallo, Elayaraja Kolanthai, Sudipta Seal, Olivier Saulnier, Michael D Taylor, Robert J Wechsler-Reya, Charles G Eberhart, Ranjan J Perera

Faculty, Staff and Students Publications

Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2-7, as a potential therapeutic target in group 3 (G3) MBs. lnc-HLX-2-7 RNA specifically accumulates in the promoter region of HLX, a sense-overlapping gene of lnc-HLX-2-7, which activates HLX expression by recruiting multiple factors, including enhancer elements. RNA sequencing and chromatin immunoprecipitation reveal that HLX binds to and activates the promoters of several oncogenes, including TBX2, LIN9, HOXM1, and MYC. Intravenous treatment with cerium-oxide-nanoparticle-coated antisense oligonucleotides targeting lnc-HLX-2-7 (CNP-lnc-HLX-2-7) inhibits tumor growth by 40%-50% in an intracranial MB xenograft mouse …

Examining The Perception Of Fresh Produce Growers On Agricultural Sustainability And Diversification, Randy Ackah

Theses and Dissertations

To meet the increasing food demand of a growing population, adopting sustainable practices should be considered a need rather than a preference. Despite the economic benefits of agricultural production, some activities performed have been identified to have detrimental effects, especially on the environment. Most of the environmental impact of agriculture usually stems from the management practices and input materials used. One way of ensuring sustainable agriculture has been identified to be agricultural diversification. Available evidence indicates that horticultural crops such as fruits and vegetables play an important role in agricultural diversification. For the fruit and vegetable industry to achieve its …

Impact Of Infestation Of Flour By Stored Food Pest Insects Ephestia Kuehniella On Quality Flour: Physico-Chemical Analyses, Hadjira Bendjedid, Samira Yezli-Touiker, Asma Taffar, Amina Yezli, Nabila Souileh

Journal of Bioresource Management

The primary reason for significant post-harvest losses globally stems from the infestation of insect pests. These beetles, as they progress through their life cycle, lead to the deterioration of stored food, capable of decimating an entire inventory within a remarkably brief timeframe. Quality control is a system that monitors product quality, assuring and detecting any spoilage of a product, the impact of infestation of flour by pairs of stored food pest insects E. kuehniella on quality flour was evaluated by physicochemical analyses over time. Provoked exposure of 200 g of flour to 5, 10, and 20 couples of Ephestia keuhniella …

Pre And Post Breeding Morphometric Profile Of European Rabbit (Oryctolagus Cuniculus), Rao Zahid Sattar, Rana Manzoor Ahmad, Abdul Majid Khan, Muhammad Altaf, Muhammad Rizwan, Sajjad Yaseen

Journal of Bioresource Management

After 1950s, a continuous decline in the population of Oryctolagus cuniculus has urged the IUCN to declare it an endangered species. There is a serious need to take conservational steps for Oryctolagus cuniculus breeds by research work on their different morphological and physiological aspects. The current study evaluates the growth of European rabbit through morphometric profile at pre breeding, post 1^st breeding and post 2^nd breeding stages in order to find out the growth trends of the European rabbits at different breeding stages. The studied sample comprised of 42 pairs for each breed (New Zealand White and American …

Usage Of Almond And Thyme Oils For The Enhancement Of Shelf Life Of Different Fish Species, Aneeza Kanwal, Roheela Yasmeen, Saima Nazir, Shumaila Usman, Bushra Nisar Khan

Journal of Bioresource Management

Fish is an important source of protein for millions of people around the globe and it's often a healthier option compared to some other meats. However, the fish industry is facing a storage challenge in the form of rapid spoilage and deterioration of freshness due to bacterial growth and enzymatic activity. The usage of oils in fish can enhance shelf life by creating a protective barrier. This research was designed to see the effects of thyme and almond oil on nutritional profile and shelf life of fish. The three fish species rohu (Labeo rohita), Mali (Wallago attu) …