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Timing Along The Cardiac Cycle Modulates Neural Signals Of Reward-Based Learning, Elsa F. Fouragnan, Billy Hosking, Yin Cheung, Brooke Prakash, Matthew Rushworth, Alejandra Sel Apr 2024

Timing Along The Cardiac Cycle Modulates Neural Signals Of Reward-Based Learning, Elsa F. Fouragnan, Billy Hosking, Yin Cheung, Brooke Prakash, Matthew Rushworth, Alejandra Sel

School of Psychology

Natural fluctuations in cardiac activity modulate brain activity associated with sensory stimuli, as well as perceptual decisions about low magnitude, near-threshold stimuli. However, little is known about the relationship between fluctuations in heart activity and other internal representations. Here we investigate whether the cardiac cycle relates to learning-related internal representations – absolute and signed prediction errors. We combined machine learning techniques with electroencephalography with both simple, direct indices of task performance and computational model-derived indices of learning. Our results demonstrate that just as people are more sensitive to low magnitude, near-threshold sensory stimuli in certain cardiac phases, so are they …


"Moloch Of The Present Mode": Women's Short Hairstyles In Nineteenth-Century American Society, Jack Tingey Apr 2024

"Moloch Of The Present Mode": Women's Short Hairstyles In Nineteenth-Century American Society, Jack Tingey

The Thetean: A Student Journal for Scholarly Historical Writing

An article from Indianapolis journal in 1883 reported on the phenomenon of women cutting their hair short in the name of fashion, describing the process of a woman cutting off her long hair as akin to sacrificing virtue to the "Moloch of the present mode." Today, short hairstyles are more commonly associated with the bob of the Roaring Twenties, an era historians and popular culture recognize as one of excess, social change, and new innovations. But short hair on women was by no ~ans new in the 1920s. The bob was not the first short hairstyle in the United States …


Maya-Catholic Theologian: The Influence Of Maya Theology On Catholic Doctrine In The Morley Manuscript, Travis Meyer Apr 2024

Maya-Catholic Theologian: The Influence Of Maya Theology On Catholic Doctrine In The Morley Manuscript, Travis Meyer

The Thetean: A Student Journal for Scholarly Historical Writing

In 1576, at the height of Catholic evangelization in the Yucatan Peninsula in Mexico, an unnamed Catholic preacher met regularly with a congregation of indigenous Maya to teach them the doctrine of Christianity. He taught them about the biblical creation, as well as the nature of God and the devil, all from his own original doctrinal instructional manual. This preacher was also a Maya himself Between the years 1500 and 1800, only about 1,100 European-descended Catholic friars ministered to the tens of millions of Maya in Mesoamerica. Because there were so many natives and so few friars, they could not …


Healing A Generation; Implementation Of Higher Education Curricula For Venezuelan Journalism Students Living Under Structural Violence To Promote A Transition Into Democracy, José Luis Jiménez-Figarotti Prof. Apr 2024

Healing A Generation; Implementation Of Higher Education Curricula For Venezuelan Journalism Students Living Under Structural Violence To Promote A Transition Into Democracy, José Luis Jiménez-Figarotti Prof.

The SUNY Journal of the Scholarship of Engagement: JoSE

Venezuela's sociopolitical landscape has deteriorated significantly over the past decade, culminating in a profound humanitarian crisis. This ethnography, conducted from 2015 to the present, explores the experiences of a study group comprising 2000 Venezuelan communication college students, aged 17 to 25, who navigate structural violence while striving for quality higher education. The research employed a multifaceted approach, encompassing interviews, focus groups, and observations. Additionally, this qualitative study examines the outcomes of implementing an interdisciplinary journalism curriculum grounded in human rights and media activism, complemented by online sessions and an environmental education component. This educational project aims to foster critical thinking …


Water Use Efficiency In Chilean And Argentine Humid Temperate Grass-Legume Pastures, H G. Landi, M H. Wade, V Garcia De Cortazar, D E. Dalla Valle Apr 2024

Water Use Efficiency In Chilean And Argentine Humid Temperate Grass-Legume Pastures, H G. Landi, M H. Wade, V Garcia De Cortazar, D E. Dalla Valle

IGC Proceedings (1977-2023)

At two sites in Argentina and Chile five levels of water input were applied to four sown pastures of varying ages during spring and summer. The pastures consisted principally of C3 grasses and legumes, some of which were sown such as Lolium perenne, Trifolium repens, Dactylis glomerata. Dry matter (DM) production was measured and related to the estimated total evapotranspiration (ET): responses were both highly linear. Both responses to ET and absolute yields were higher at the Argentinian than at the Chilean site: respectively 10.7 and 15.2 kg DM/mm water evapotranspired. Nevertheless the calculated indices of sensitivity (Ky) of Doorenbos …


Leaf Anatomy And Ultrastructure Of Poa Ligularis After Defoliation And Water Stress, M G. Klich, R E. Brevedan, S C. Villamil Apr 2024

Leaf Anatomy And Ultrastructure Of Poa Ligularis After Defoliation And Water Stress, M G. Klich, R E. Brevedan, S C. Villamil

IGC Proceedings (1977-2023)

The objective of this study was to determine the effect of defoliation and water stress on leaf anatomy and the mesophyll cell ultrastructure of Poa ligularis. Anatomical differences were detected mainly at epidermal level. Under water stress, leaf roughness was enhanced since the epidermal-cell surface contours became conspicuous. Under defoliation the microscopic roughness decreased as a result of fewer epicuticular wax crystals being formed. Defoliation produced an enhancement of the interlamellar spaces in the irrigated plantís chloroplast. Under no defoliation conditions, chloroplast structure was not affected by water stress. When subjected to water stress, lightly defoliated plants presented chloroplasts …


Leaf Growth And Anatomy During Winter Droughting Of Tetrachne Dregei Plants, M G. Klich, R E. Brevedan, H Laborde Apr 2024

Leaf Growth And Anatomy During Winter Droughting Of Tetrachne Dregei Plants, M G. Klich, R E. Brevedan, H Laborde

IGC Proceedings (1977-2023)

The purpose of this work was to study the leaf growth and anatomy of Tetrachne dregei plants when they were subjected to a winter drought period. Plants were grown in semicontrolled conditions under two soil moisture regimes: irrigated and non-irrigated. Anatomical characterization was made using optical and scanning electron microscopy. No differences were found in stomatal index, stomatal length and epidermal cell size, between irrigated and non-irrigated plants. The adaxial epidermis of water stressed plants was more pubescent. Leaf abaxial epidermis of non-irrigated plants showed more intercostal plates of crystallized epicuticular wax than that of the irrigated ones. Leaf tissue …


The Interaction Between Root Distribution And Pasture Growth During Water Deficit, D J. Barker, N Dymock Apr 2024

The Interaction Between Root Distribution And Pasture Growth During Water Deficit, D J. Barker, N Dymock

IGC Proceedings (1977-2023)

Quantification of water-limited pasture growth is of interest in agriculture since it allows prediction of impaired animal production during drought, and is the basis for scheduling irrigation. Experimental work on two dairy pastures 25 km south-west of Palmerston North, New Zealand found 50% of root mass was in the top 2.3 cm of soil. Soil moisture was, similarly, not uniformly distributed down the soil profile and dried most rapidly in the top 20†cm of soil. Leaf appearance rate was more strongly correlated with water status nearer the soil surface (r = 0.52 & 0.63 for 0-5 & 10-15 cm depth, …


Management Of Tall Wheatgrass Based On The Leaf Appearance During Spring, S Laplace, M A. Brizuela, M S. Cid Apr 2024

Management Of Tall Wheatgrass Based On The Leaf Appearance During Spring, S Laplace, M A. Brizuela, M S. Cid

IGC Proceedings (1977-2023)

The objectives of this study were to determine the date of transition from vegetative to reproductive stage at different defoliation frequencies in tall wheatgrass (Thinopyrum ponticum). In addition, we assessed the relationship between the spring temperatures and the rate of leaf appearance. To meet both objectives we had defoliated and undefoliated plant plots at Balcarce Experiment Station, Argentina. The different defoliation treatments (every 7, 14, 21 and 28 days) delayed or avoided the manifestation of the reproductive stage. The apexes of undefoliated plants began to rise on October 12, while defoliated ones slowed that elevation or the same …


Fertilizer Nitrogen And Morphogenetic Response In Avena Sativa And Lolium Multiflorum, F Lattanzi, M A. Marino, A Mazzanti Apr 2024

Fertilizer Nitrogen And Morphogenetic Response In Avena Sativa And Lolium Multiflorum, F Lattanzi, M A. Marino, A Mazzanti

IGC Proceedings (1977-2023)

A field experiment was carried out at the EEA Balcarce, INTA, Argentina (37° 45’LS, 58° 18’LW) to determine whether Leaf Appearance Rate (LAR) was affected by N fertilization in Italian ryegrass (Lolium multiflorum Lam.) and forage oats (Avena sativa). N treatments (0, 50, 100, 150, 200 and 250 kg N ha-1) were applied in winter 1995, after a defoliation. Subsequently, number of leaves per tiller was determined on 45 labelled tillers in each treatment twice a week. LAR was calculated as the slope of the linear regression of number of leaves on thermal time (air temperature, base …


The Analysis Of Dynamic Interaction In Legume Binary Mixture Under Controlled Conditions Of Irrigation And Clipping, M S. Vrahnakis, B Noitsakis, Z Koukoura Apr 2024

The Analysis Of Dynamic Interaction In Legume Binary Mixture Under Controlled Conditions Of Irrigation And Clipping, M S. Vrahnakis, B Noitsakis, Z Koukoura

IGC Proceedings (1977-2023)

The objective of this study was to analyse the type of interference that occurred between the annual legume species, purple clover (Trifolium purpureum L.) and narrow leaved crimson clover (Trifolium angustifolium Loisel. ), growing in mixed conditions under two different watering regimes and two different clipping treatments. A replacement series experiment was conducted in pots placed in the field. The above ground biomass (gr/plant) were measured. The recently proposed Inverse Linear Model was implied in order to analyse the competitive interaction between the above species. The results suggest that Tr. purpureum was the superior competitor to Tr. angustifolium …


Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xxx. Parabuthus (Buthidae) (Part Iii), With Description Of Three New Species From Somaliland And Occurrence Of Parabuthus Eritreaensis Kovařík, 2003, František Kovařík, Graeme Lowe, Hassan Sh A. Elmi, František Šťáhlavský Apr 2024

Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xxx. Parabuthus (Buthidae) (Part Iii), With Description Of Three New Species From Somaliland And Occurrence Of Parabuthus Eritreaensis Kovařík, 2003, František Kovařík, Graeme Lowe, Hassan Sh A. Elmi, František Šťáhlavský

Euscorpius

A new record of an adult female of Parabuthus eritreaensis Kovařík, 2003 in Somaliland confirms true distribution of this species, already discussed in Kovařík et al. (2016: 19–21). Three new species are described from Somaliland, P. dorisae sp. n., P. evae sp. n., and P. quincyae sp. n.. The hemispermatophore of P. dorisae sp. n. is illustrated and described. In addition to the analyses of external morphology and hemispermatophore, we have provided descriptions of the karyotypes of P. dorisae sp. n. and P. quincyae sp. n. Despite the presence of multivalents (CVIII and CXIV), both species exhibit karyotypes with 2n=16 …


Transgenic Overexpression Of Ctrp3: Possible Protection Against Non-Alcoholic Fatty Liver Disease, Noah Wren, Allan Forsman Apr 2024

Transgenic Overexpression Of Ctrp3: Possible Protection Against Non-Alcoholic Fatty Liver Disease, Noah Wren, Allan Forsman

Appalachian Student Research Forum

All tissues used in this study were generated in a study in the laboratory of Dr. Johnathan Peterson. The study was designed to determine the relationship between C1q TNF-related protein-3 (CTRP3) and non-alcoholic fatty liver disease. It is estimated that over 3 million Americans suffer from non-alcoholic fatty liver disease. This disease also has a higher prevalence in persons with Type II diabetes and various cardiac pathologies. Transgenic mice bred to over express CTRP3, were generated by mating female C57 mice with male, 4513+ mice. Littermates without the CTRP3 transgene were used as wild-type (WT) controls. All mice used in …


Fgf21 Receptor Knock Out; Its Role In Lipid Metabolism In The Liver, Tiffany Morris, Ummah S. Nisar, George Youngberg, Allan D. Forsman Apr 2024

Fgf21 Receptor Knock Out; Its Role In Lipid Metabolism In The Liver, Tiffany Morris, Ummah S. Nisar, George Youngberg, Allan D. Forsman

Appalachian Student Research Forum

Fibroblast Growth Factor 21 (FGF21) has been shown to be a key player in the intricate pathway regulating lipid metabolism and lipid reduction in the liver. It is also known to regulate metabolic expenditure and insulin sensitivity. Transgenic fibroblast growth factor receptor knock out (Fgfr1 KO) mice are genetically altered to lack the receptor for FGF21. There have been no studies that have investigated the ramifications of interrupting the FGF21 pathway in the liver. This study analyzed liver tissues from 4 different treatment groups of mice: 1 - transgenic Fgfr1 KO mice fed a very high fat diet (VHFD), 2 …


Skin Irritation Of Capsicum Patches By In Vitro Study And Human Repeated Insult Patch Test., Apirada Sucontphunt, Tun Chusut, Thaniya Wannakup, Paninee Chetprayoon, Laksana Charoenchai Apr 2024

Skin Irritation Of Capsicum Patches By In Vitro Study And Human Repeated Insult Patch Test., Apirada Sucontphunt, Tun Chusut, Thaniya Wannakup, Paninee Chetprayoon, Laksana Charoenchai

The Thai Journal of Pharmaceutical Sciences

The use of capsaicin, a natural active compound for pain management, in various health products has continuously increased. Capsaicin has been shown to suppress pain by decreasing substance P; however, the safety information of capsaicin formulations requires support from numerous studies. For that reason, in this research, the skin irritancy of a capsaicin hydrogel transdermal patch was evaluated and compared to that of a commercial relief patch by in-vitro skin irritation and a human repeated insult patch test (HRIPT). In-vitro skin irritation of samples was performed using reconstructed human epidermis. The percentage of tissue viability was evaluated and compared. For …


Visual Analytics In Explaining Neural Networks With Neuron Clustering, Gulsum Alicioglu, Bo Sun Apr 2024

Visual Analytics In Explaining Neural Networks With Neuron Clustering, Gulsum Alicioglu, Bo Sun

College of Science & Mathematics Departmental Research

Deep learning (DL) models have achieved state-of-the-art performance in many domains. The interpretation of their working mechanisms and decision-making process is essential because of their complex structure and black-box nature, especially for sensitive domains such as healthcare. Visual analytics (VA) combined with DL methods have been widely used to discover data insights, but they often encounter visual clutter (VC) issues. This study presents a compact neural network (NN) view design to reduce the visual clutter in explaining the DL model components for domain experts and end users. We utilized clustering algorithms to group hidden neurons based on their activation similarities. …


Improved Cardiac Auscultation Competency Interweaving Visual, Auditory, And Tactile Stimuli: A Preliminary Study, Harrison A Patrizio, Riley Phyu, Bum Kim, Nils V Brolis Apr 2024

Improved Cardiac Auscultation Competency Interweaving Visual, Auditory, And Tactile Stimuli: A Preliminary Study, Harrison A Patrizio, Riley Phyu, Bum Kim, Nils V Brolis

Rowan-Virtua School of Osteopathic Medicine Departmental Research

METHODS: A pilot randomized controlled trial was conducted at our institution's simulation center with 32 first year medical students from a single medical institution. Participants were randomly divided into two equal groups and completed an educational module on the identification and pathophysiology of five common cardiac sounds. The control group utilized traditional education methods, while the interventional group incorporated multisensory stimuli. Afterwards, participants listened to randomly selected cardiac sounds and competency data was collected through a multiple-choice post-assessment in both groups. Mann-Whitney U test was used to analyze the data.

Results: Data were analyzed using the Mann-Whitney U test. Diagnostic …


The Student Movement Volume 108 Issue 20: Breaking News: Curfew Is Now Sunset: Effective Immediately, Grace No, Reagan Mccain, Savannah Tyler, Madison Vath, Corinna Bevier, Nate Miller, Aiko J. Ayala Rivers, Andrew Francis, Ana K. Zelidon, Jonathan Clough, Abby Shim, Bella Hamann, Anna Rybachek, Melissa Moore, Nicholas Gunn Apr 2024

The Student Movement Volume 108 Issue 20: Breaking News: Curfew Is Now Sunset: Effective Immediately, Grace No, Reagan Mccain, Savannah Tyler, Madison Vath, Corinna Bevier, Nate Miller, Aiko J. Ayala Rivers, Andrew Francis, Ana K. Zelidon, Jonathan Clough, Abby Shim, Bella Hamann, Anna Rybachek, Melissa Moore, Nicholas Gunn

The Student Movement v. 108 (2023-2024)

HUMANS

Chivalry Not Dead: Students Spotted in Shining Armor, Grace No

Interview with the Breakfast Burrito, Interviewed by Regan McCain

VeggieTales Cast: Hot Takes From the Fridge, Interviewed by Savannah Tyler

ARTS & ENTERTAINMENT

Why the 'Daughters of the Revolution' Stay Mad, Madison Vath

Jaws 6: The Jawsical, Corinna Bevier

I UNDERSTAND MARY POPPINS' ESSENCE MORE THAN THE FILM'S WRITERS, Nate Miller

Pitagorical decision: Music Department opens Triangle Performance Major, Aiko J. Ayala Rivers

Sabrina Carpenter Comes to Berrien, Reagan McCain

NEWS

Soccer (Football) Legend Lionel Messi to Visit Berrien County, Andrew Francis

Satire: Severe Weather Stirs Mixed Emotions on …


Brief Of Amicae Curiae Susan Boundy-Sanders And Paula Waters In Support Of Friends Of Sammamish Valley And Futurewise, King County V. Friends Of Sammamish Valley, Washington State Supreme Court Docket No. 102177-1, William Bailey Apr 2024

Brief Of Amicae Curiae Susan Boundy-Sanders And Paula Waters In Support Of Friends Of Sammamish Valley And Futurewise, King County V. Friends Of Sammamish Valley, Washington State Supreme Court Docket No. 102177-1, William Bailey

Court Briefs

No abstract provided.


An In Vitro Neurogenetics Platform For Precision Disease Modeling In The Mouse., Daniel Cortes, Mélanie Escudero, Austin C Korgan, Arojit Mitra, Alyssa Edwards, Selcan Aydin, Steven C. Munger, Kevin Charland, Zhong-Wei Zhang, Kristen M S O'Connell, Laura G Reinholdt, Martin Pera Apr 2024

An In Vitro Neurogenetics Platform For Precision Disease Modeling In The Mouse., Daniel Cortes, Mélanie Escudero, Austin C Korgan, Arojit Mitra, Alyssa Edwards, Selcan Aydin, Steven C. Munger, Kevin Charland, Zhong-Wei Zhang, Kristen M S O'Connell, Laura G Reinholdt, Martin Pera

Faculty Research 2024

The power and scope of disease modeling can be markedly enhanced through the incorporation of broad genetic diversity. The introduction of pathogenic mutations into a single inbred mouse strain sometimes fails to mimic human disease. We describe a cross-species precision disease modeling platform that exploits mouse genetic diversity to bridge cell-based modeling with whole organism analysis. We developed a universal protocol that permitted robust and reproducible neural differentiation of genetically diverse human and mouse pluripotent stem cell lines and then carried out a proof-of-concept study of the neurodevelopmental gene DYRK1A. Results in vitro reliably predicted the effects of genetic background …


The Identification Of The Flower Thrips, Frankliniella Karny (Thysanoptera: Thripidae) Intercepted At U. S. Ports Of Entry, Thomas L. Skarlinsky Ii Apr 2024

The Identification Of The Flower Thrips, Frankliniella Karny (Thysanoptera: Thripidae) Intercepted At U. S. Ports Of Entry, Thomas L. Skarlinsky Ii

Insecta Mundi

United States port of entry interception data revealed that Frankliniella Karny (Thysanoptera: Thripidae) was the most frequently intercepted genus of Thripidae. No published identification resource for intercepted Frankliniella is available to United States Department of Agriculture (USDA) port of entry entomology identifiers. A morphological review of intercepted species was conducted. A dichotomous key for the identification of intercepted slide mounted adult females was created. Morphological diagnosis, description of each species with their geographic region(s) of origin and frequency of interception is provided.

ZooBank registration. urn:lsid:zoobank.org:pub:403B362E-9A7F-4385-A0F1-9DB87FE09AD2


Predicting The Potential Distribution Of Pseudococcus Longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) In South Korea Using A Climex Model, Su Bin Kim, Soo-Jung Suh Apr 2024

Predicting The Potential Distribution Of Pseudococcus Longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) In South Korea Using A Climex Model, Su Bin Kim, Soo-Jung Suh

Insecta Mundi

Pseudococcus longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) is a widely-distributed pest that feeds on many economically important hosts, particularly tropical fruits and ornamentals. The potential distribution of this mealybug pest in South Korea remains a primary concern because of its high incidence of interceptions screened during inspection. Hence, this species prompted a modelling effort to assess its potential risk of introduction. Potential risk maps were developed for this pest with a CLIMEX model based on occurrence records under environmental data. The potential distribution of these pests in South Korea in the 2020s, 2050s and 2090s was projected based on the RCP 8.5 …


Evaluation Of Yield And Physicochemical Quality Of Pentadesma Butyracea Butter Obtained By Different Traditional Extraction Methods In Ghana, Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Jacob K. Agbenorhevi, Nana Baah Pepra-Ameyaw Apr 2024

Evaluation Of Yield And Physicochemical Quality Of Pentadesma Butyracea Butter Obtained By Different Traditional Extraction Methods In Ghana, Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Jacob K. Agbenorhevi, Nana Baah Pepra-Ameyaw

Food Science Faculty Articles and Research

Pentadesma butyracea seed butter or fat (PBSB) is a vegetable fat extracted from the seeds of the P. butyracea plant. The butter has potential use in the food, pharmaceutical, and cosmetic industries. The study investigated traditional PBSB processing methods in Ghana and evaluated their effects on yield, physicochemical parameters, and fatty acid composition. Four traditional extraction methods were identified and evaluated, and these methods are direct wet extraction of PBSB from a fresh mixture of the seed paste and water (DEW); wet extraction of PBSB from a 12-hour fermented mixture of the seed paste and water (FWO); direct wet extraction …


Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi Apr 2024

Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi

Pharmacy Faculty Articles and Research

Breast cancer remains a significant global health concern, emphasizing the critical need for effective treatment strategies, especially targeted therapies. This systematic review summarizes the findings from in vitro and in vivo studies regarding the therapeutic potential of exosomes as drug delivery platforms in the field of breast cancer treatment. A comprehensive search was conducted across bibliographic datasets, including Web of Science, PubMed, and Scopus, using relevant queries from several related published articles and the Medical Subject Headings Database. Then, all morphological, biomechanical, histopathological, and cellular-molecular outcomes were systematically collected. A total of 30 studies were identified based on the Preferred …


The Voice Actor And Their Double: Working As A Voice Actor And Teaching Voice Acting In The Age Of Ai Voice Cloning, Adam Paul Apr 2024

The Voice Actor And Their Double: Working As A Voice Actor And Teaching Voice Acting In The Age Of Ai Voice Cloning, Adam Paul

Tradition Innovations in Arts, Design, and Media Higher Education

The rapid development of Artificial Intelligence (AI) and voice cloning technology presents significant challenges and opportunities in the field of voice acting and performing arts. This article explores the profound transformations taking place in the voiceover industry due to the convergence of AI, voice synthesis, and personal voice cloning technologies. The author, a seasoned voice actor, reflects on the impact of these advancements on his profession, from the democratization of voiceover tools to the emergence of AI-generated voices that closely mimic human speech.

The article delves into the intricate interplay between technology and human creativity, investigating the implications for voice …


Predictors Of Prep Uptake By Black Gay And Bisexual Men In Ohio, Ade Elisha Apr 2024

Predictors Of Prep Uptake By Black Gay And Bisexual Men In Ohio, Ade Elisha

Walden Dissertations and Doctoral Studies

No abstract provided.


Local Ecological Knowledge, Education, And Bilingualism: Ethnography Of A Stem Program For Elementary Students In Southwestern Florida, Barbara D. Herrera Apr 2024

Local Ecological Knowledge, Education, And Bilingualism: Ethnography Of A Stem Program For Elementary Students In Southwestern Florida, Barbara D. Herrera

USF Tampa Graduate Theses and Dissertations

In response to the limited inclusion of cultural relevant pedagogy in Science, Technology, Engineering, and Mathematics (STEM) centered educational programs, this study illustrates dynamics that encourage inclusivity and provide a space for minority students to develop self-efficacy while also exposing them to formal modes of STEM knowledge. Elementary level English/Spanish speaking children were taught local ecological knowledge (LEK) during a STEM summer program in a city in Southwestern Florida. The use of participant observation, group interviews with the students, and interviews with the educators allowed for an in-depth analysis of the program and the established goals. This study provides insight …


Csf Biomarkers Of Immune Activation And Alzheimer's Disease For Predicting Cognitive Impairment Risk In The Elderly, Francis Shue, Rachel Hendrix, Jason Ulrich, Rachel L Henson, William Knight, Chengjie Xiong, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M Holtzman, Et Al. Apr 2024

Csf Biomarkers Of Immune Activation And Alzheimer's Disease For Predicting Cognitive Impairment Risk In The Elderly, Francis Shue, Rachel Hendrix, Jason Ulrich, Rachel L Henson, William Knight, Chengjie Xiong, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M Holtzman, Et Al.

2020-Current year OA Pubs

The immune system substantially influences age-related cognitive decline and Alzheimer's disease (AD) progression, affected by genetic and environmental factors. In a Mayo Clinic Study of Aging cohort, we examined how risk factors like APOE genotype, age, and sex affect inflammatory molecules and AD biomarkers in cerebrospinal fluid (CSF). Among cognitively unimpaired individuals over 65 (


Subcellular Pathways Through Vglut3-Expressing Mouse Amacrine Cells Provide Locally Tuned Object-Motion-Selective Signals In The Retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam Mccoy, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan Apr 2024

Subcellular Pathways Through Vglut3-Expressing Mouse Amacrine Cells Provide Locally Tuned Object-Motion-Selective Signals In The Retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam Mccoy, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan

2020-Current year OA Pubs

VGluT3-expressing mouse retinal amacrine cells (VG3s) respond to small-object motion and connect to multiple types of bipolar cells (inputs) and retinal ganglion cells (RGCs, outputs). Because these input and output connections are intermixed on the same dendrites, making sense of VG3 circuitry requires comparing the distribution of synapses across their arbors to the subcellular flow of signals. Here, we combine subcellular calcium imaging and electron microscopic connectomic reconstruction to analyze how VG3s integrate and transmit visual information. VG3s receive inputs from all nearby bipolar cell types but exhibit a strong preference for the fast type 3a bipolar cells. By comparing …


Blocking Senescence And Tolerogenic Function Of Dendritic Cells Induced By Γδ Treg Cells Enhances Tumor-Specific Immunity For Cancer Immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng Apr 2024

Blocking Senescence And Tolerogenic Function Of Dendritic Cells Induced By Γδ Treg Cells Enhances Tumor-Specific Immunity For Cancer Immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng

2020-Current year OA Pubs

BACKGROUND: Regulatory T (Treg) cells are a key component in maintaining the suppressive tumor microenvironment and immune suppression in different types of cancers. A precise understanding of the molecular mechanisms used by Treg cells for immune suppression is critical for the development of effective strategies for cancer immunotherapy.

METHODS: Senescence development and tolerogenic functions of dendritic cells (DCs) induced by breast cancer tumor-derived γδ Treg cells were fully characterized using real-time PCR, flow cytometry, western blot, and functional assays. Loss-of-function strategies with pharmacological inhibitor and/or neutralizing antibody were used to identify the potential molecule(s) and pathway(s) involved in DC senescence …