The Impact Of Nutrition On Insecticide Resistance And Gene Expression In Aedes Aegypti, Esmeralda Guadalupe Rosas

Theses and Dissertations

The development of insecticide resistance in Aedes aegypti, a major vector of dengue and Zika viruses, threatens vector control efforts, particularly in endemic regions such as South Texas. Insecticides remain widely used; however, their overuse has accelerated metabolic resistance mediated by cytochrome P450 enzymes. Environmental factors such as larval nutrition may influence mosquito physiology and resistance-associated gene expression, yet this relationship remains poorly understood. This study examines how larval nutritional conditions affect the expression of cytochrome P450 genes linked to pyrethroid resistance in Aedes aegypti. Larvae were reared under five dietary treatments differing in lipid and protein ratios, and adults …

Identification Of Peptides For A Muc13 Cancer Vaccine, Abigail Olivia Gomez

Theses and Dissertations

Mucin 13 (MUC13) is a transmembrane glycoprotein that is frequently overexpressed in epithelial cancers. Its extracellular domains and cytoplasmic signaling potential contribute to disrupted cell adhesion, increased invasion, and cancer-promoting pathways, making MUC13 a promising target for immunotherapy. This project used an in-silico approach to identify MUC13-derived peptides predicted to bind HLA class I molecules and support CD8+ T cell-mediated immune responses. Bioinformatics tools were used to screen candidate epitopes for HLA binding affinity, antigenicity, toxicity, IFN-γ-inducing potential, and population coverage, allowing rational prioritization of peptide candidates for experimentation. Selected peptides were evaluated in THP-1-derived macrophages using RT-PCR, Western blotting, …

Teacher Stories In A Place-Based Science Education Program In The Trans-Nueces Region, Brian Craig Gabrysch

Theses and Dissertations

This qualitative study examines the emerging professional narratives of five educators involved in the Integrated Oceans Program at a coastal South Texas school district situated within the Trans-Nueces region. Guided by the central research question—What are the emerging teacher stories from a place-based science program in the Trans-Nueces region, and what do we learn about place-based science education from the narratives?—the study employs narrative inquiry methodology following Riessman (2008) and Bruner (1985) to investigate how educators construct meaning from their practice within a program anchored to the Laguna Madre wetlands ecosystem.

The theoretical framework integrates interpretivism (Benton & Craib, 2010), …

A Case Study Of One-To-One Mobile Teaching And Learning Environments Measuring Creativity In A Rural Elementary School In Deep South Texas, David Warren Hernandez

Theses and Dissertations

This qualitative case study examined how creativity is enacted within rural one-to-one mobile teaching and learning environments in Deep South Texas. Grounded in the frameworks of mobile learning affordances (Klopfer et al., 2002), the Technological, Pedagogical, and Content Knowledge (TPACK) framework, and the SAMR model, the study explored how instructional practices, student agency, and contextual conditions influenced creative learning experiences in an elementary school setting. Data were collected from five elementary teachers at a rural South Texas district and included semi-structured interviews, classroom observations, and samples of student-created artifacts. Data analysis followed a systematic process of first-cycle coding, second-cycle axial …

Linking North American Demographic Trends To Mexican Non-Breeding Grounds In A Migratory Warbler, Majuwana Gamage Dulanthi Dileka Kariyawasam

Theses and Dissertations

Migration enables species to exploit seasonal resources despite high energetic costs and mortality risks, making it a key focus for conservation under environmental change. I investigated migratory connectivity in Orange-crowned Warblers using stable hydrogen isotopes (δ²H) from feathers collected at nine non-breeding sites across Mexico. Results indicated generally weak connectivity (MC = 0.18), with most sites hosting individuals from six breeding clusters across Canada and the United States. However, one northwestern breeding group showed strong connectivity, suggesting crosswise migration to eastern Mexico. By integrating these findings with long-term Breeding Bird Survey data, I detected contrasting population trends, with Pacific Coast …

Resource Allocation Trade-Offs Between Longevity And Reproduction In Daphnia Magna, Amelia Pearson

Electronic Theses and Dissertations

Although trade-offs between longevity and reproduction have been described for a long time, the genetic mechanisms by which organisms modulate allocation of resources between these two essential processes remain poorly understood, due to their complex nature and their modification by existing nutritional states and environmental cues. Daphnia magna represents a valuable model for investigation in this area due to their moderate lifespan and cyclic parthenogenetic mode of reproduction, allowing for the easy study of gene by environment interactions. This dissertation first investigates the change in mortality, reproduction, activity, and gene expression when fully fed Daphnia and calorically restricted Daphnia are …

Study Of Global Panel Of Soybean Accessions For Nitrogen Use Efficiency Using Association Mapping, Rita Bhandari

Theses

Soybean (Glycine max [L.] Merr.) is a leguminous crop valued for its high protein, oil content, and other essential nutrients. Global production has significantly increased, with Brazil, the United States, and Argentina being the leading producers. In the U.S., Illinois, Iowa, and Minnesota rank as the top soybean-producing states. Nitrogen (N) is a predominant nutrient required for optimal soybean growth and productivity, particularly in high-yielding varieties. While biological nitrogen fixation and soil mineral N supply part of the plant’s N requirement, synthetic fertilizers are commonly used to meet the remaining demand. However, only 30–50% of applied N is taken up …

Evaluation Of Otolith Microchemistry For Identifying Walleye Stocked As Fry Or Fingerlings, Joshua Fluur

Theses

Walleye (Sander vitreus) is a popular sport fish whose populations are often supported by maintenance or supplemental stocking, with most fish stocked as fry, fingerlings, or advanced fingerlings. Evaluation of stocking efficacy is important to inform decisions regarding fish stocking rates and sizes and allocating hatchery fish to locations where maintenance or supplemental stocking is most needed. Several types of artificial tags or marks have been proven useful in the identification of stocked fish, but they often have various drawbacks. Natural chemical markers in otoliths offer several advantages compared to conventional tags or marks and can be used to identify …

Effects Of Androgens And Chronic Stress On Anxiety Related Behaviors And Stress Induced Neural Activity In Alzheimer’S Disease Mice, Mekenna Hobson

Psychology

Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is characterized by a progressive decline in cognitive function. Neuropathologically, AD is shown as cortical intracellular neurofibrillary tangles (NFT) and extracellular β-amyloid (Aβ) plaques (Riverol & Lopez 2011) along with cerebral hypometabolism, neuroinflammation, and neuronal death (Armstrong et al. 2021). There are indications that early to mid-life stress has an impact on the risk of cognitive decline and plays a part in the pathology of the neurodegeneration that comes with AD (Armstrong et al. 2021). Psychological stress contributes to emotional states like depression and anxiety. It has been shown that people …

Perceptions On The Moral And Ethical Applications Of Generative Ai In Creative Game Development, Isabella Maccera

Emergency Preparedness, Homeland Security, and Cybersecurity

As AI tools become increasingly embedded in creative industries, they introduce both opportunities for efficiency and concerns regarding authorship, intellectual property, job displacement, and professional identity. Guided by three research questions focused on creativity, ethics, and workflow adaptation, this research employs a qualitative methodology using semi-structured interviews to capture participant experiences and interpretations. This study frames GenAI not as an isolated tool, but as part of a broader system that reshapes creative labor, collaboration, and organizational structure. Inductive coding and thematic analysis reveal five central themes: perceptions of AI in creative workflows, ethical and intellectual property concerns, employment and identity …

Efficacy Of Implicit Bias Training Within The Hazel Park Police Department, Luke Londo

Master of Public Administration Capstone Papers

Among the many desired outcomes for uniformed police officers who undergo implicit bias training is a reduction in the level of discriminatory conduct related to such biases. Current research on the subject offers mixed results, and nearly all existing studies do not provide an empirical measurement of efficacy or other outcomes beyond officer sentiment. This case study examines and measures the impact of implicit bias trainings, which is a requirement for officers within the Hazel Park Police Department in Michigan, prior and subsequent to certification by using raw and sustained complaints of discriminatory conduct allegedly perpetrated by Hazel Park police …

A Novel Approach To Creativity Assessment: Forced Pairwise Ranking With Large Language Models, Phillip R. Gregory Jr

Master's Theses

Assessing creativity at scale remains a persistent challenge in cognitive science, as human raters are costly, slow, and often inconsistent in their judgments. This thesis introduced a novel framework for automated scientific creativity assessment using forced pairwise ranking, in which fine-tuned large language models compared response pairs and determined which was more creative. Five empirical studies were conducted using Llama-2-7B and Llama-2-13B models adapted via LoRA fine-tuning and benchmarked against human scored responses from the Scientific Creative Thinking Test. A regression baseline achieved Pearson �� = .74 on the test set, matching the human inter-rater ceiling reported in the literature. …

Building Collaborative Capacity For Coexistence With The Montana Beaver Working Group, Shane Randle

Graduate Student Portfolios, Professional Papers, and Capstone Projects

Despite beavers’ recent surge in popularity, prevailing negative attitudes and the persistence of beaver removal practices remain obstacles for those advocating living with beavers. The Montana Beaver Working Group (BWG) advances beavers’ role in ecological and community resilience through members’ collaborative efforts, including beaver-related restoration and conflict resolution projects. Bringing together people with diverse values and perspectives, the BWG builds collective understanding, develops a holistic vision for beavers in Montana, and supports members in pursuing it. As the group’s impacts and membership have grown, so too has their need to adapt. For my Civic Engagement Project, I strengthened the BWG’s …

Rooted Transformations, Ricardo D. Moctezuma

Electronic Theses, Projects, and Dissertations

In my ventures through art I realized that I underwent an experience that was tailored to my process of release. As I struggled to share my emotions, I became distant and dissociated, I felt detached from others and even from myself. This process was something I visualized in my art from, the Tears, to Self Destruction, to the Release and onto the Garden. I’ve always felt myself in a state of Release, partly healed and partly damaged. All I knew was that the garden represented a new beginning for me, I just never knew what that Garden was. Time passes …

Haunting As Heritage: Mapping The Interior And Indigenous Ghosts, Koda L. Animkii

Electronic Theses, Projects, and Dissertations

Within Stephen Graham Jones’ novella Mapping the Interior, the connections between history and identity are analyzed and emphasized through the exploration of identity formation and the impacts of settler colonialism on the self. These connections are heightened through the novella’s use of horror, as the rhetoric of the normative and monstrous within the genre holds the potential for both resistance and oppression. Looking at the genre of horror as a whole, and at the subgenres of ghost stories and hauntings more specifically, the shifting structures of the Self and the Other as established by Robin Wood’s “An Introduction to …

Serotonin 7 Receptor Modulation On Measures Of Working Memory And Anxiety, Antonio Gutierrez

Electronic Theses, Projects, and Dissertations

Serotonin (5-HT) function is critical in the regulation and homeostasis of several neural systems. Alterations in 5-HT levels can directly impact the presence of neuropsychiatric disorders such as schizophrenia. With a wide range of 5-HT receptors, the potential impact each of these modulators have on behavior is important to better understand. The 5-HT7 receptor is the most recently identified 5-HT receptor. 5-HT7 receptors can be found in the thalamus, hypothalamus, and several areas of the hippocampus. Modulation of these receptors impact circadian rhythms, hormonal regulation and memory function. Previous research has that 5-HT7 antagonist compounds lead to conflicting results, highlighting …

Raising Resilient Children: Parent Video Guide To Support Children’S Emotional Development, Perla F. Nunez-Chavez

Electronic Theses, Projects, and Dissertations

Social-emotional learning (SEL) in early childhood plays a critical role in

children’s ability to recognize emotions, regulate behavior, build relationships,

and succeed in academic settings. During the preschool years (ages 3–5),

children experience rapid emotional development and rely heavily on parents for

co-regulation, emotional modeling, and guidance. Research consistently shows

that when parents engage in emotion coaching practices, such as labeling

feelings, validating emotions, and modeling regulation strategies, children

demonstrate stronger emotional competence and improved developmental

outcomes. However, despite strong evidence supporting parent involvement in

SEL, many existing interventions are delivered through structured, in-person

programs that are often inaccessible to …

Game On! Level Up Your Teaching: A Digital Game-Based Learning Guide For Preschool Teachers, Scarlett Flores Marin

Electronic Theses, Projects, and Dissertations

Although digital game-based learning (DGBL) has emerged as a

promising technological advancement in early childhood education by offering

many developmental benefits for children, its effective implementation remains a

challenge. The integration of digital technologies in early childhood education has

led to the growing use of DGBL as an effective instructional approach with

research indicating that well-designed educational apps and games can enhance

young children’s cognitive, literacy, and social development by promoting active,

meaningful, and interactive learning experiences. DGBL encourages problem-

solving, critical thinking, and collaboration, aligning with how children naturally

learn through exploration and engagement. When used intentionally, technology

and …

Investigating Fentanyl-Xylazine Interactions: Implications For Opioid-Induced Hyperalgesia And Affective Dysregulation In Rats, Alejandra R. Lujan

Electronic Theses, Projects, and Dissertations

The growing prevalence of fentanyl adulterated with xylazine presents a major public health concern, yet the behavioral and physiological effects of this combination remain poorly characterized. This study examined the effects of acute fentanyl administration, alone and in combination with xylazine, on opioid-induced hyperalgesia, affective behavior, and mortality in male and female Sprague-Dawley rats (n=80). Rats received four fentanyl injections (60 µg/kg) administered at 15-minute intervals, with or without xylazine (0, 0.1, 0.333, or 1.0 mg/kg), as well as a saline control condition. Pain sensitivity was assessed using a hot plate assay at 6.5, 12, 24, and 48 hours post-injection. …

Encounters Of Third Space: A Case Study On Salvadoran Political Art And Identity Interplay, Breanna Delgado

Electronic Theses, Projects, and Dissertations

Third space is an in-between thought space designated for marginalized collectives, allowing multiple recontextualizations of identity interplay. However, Third Space is colonized due to western ideological influences such as criminalization of political art, stunting collective growth. This project serves to question and challenge Salvadoran political art and collective identities through questions such as why political art? Can political art be considered “safe spaces”? and dissecting the process of political art, third space meaning making, and identity interplay. Preserving the collective’s political art serves as a grassroots method of justice, accountability, and collective reparation.

I applying three conceptual frameworks: Bhabha’s (1994) …

Healing Beyond Bars: Integrated And Sustainable Recovery Models For Post-Incarcerated Women, Patricia A. Nunez, Jonathan Solomon

Electronic Theses, Projects, and Dissertations

Substance Use Disorders (SUDs) significantly impact the re-entry process for formerly incarcerated individuals, particularly Latina/x women, who face unique cultural, social, and economic challenges in accessing effective treatment. The purpose of this study is to explore the effectiveness of substance use disorder treatment programs in support of successful reentry outcomes for Latina/x women post-incarceration. Previous research on SUD treatment for this population remains limited despite growing awareness of the need for gender-responsive and culturally informed interventions. Qualitative research with an exploratory design within an interpretive research paradigm will be utilized to investigate the lived experiences of Latina/x women who have …

Effects Of Cannabinoid Agonist Win 55-212-2 On Latent Inhibition, Ashley Peterson

All Graduate Theses and Dissertations, Fall 2023 to Present

The endocannabinoid system (ECS) is a modulatory system that helps regulate brain functions, including learning and memory, influencing processes such as latent inhibition (LI). LI refers to the slower association formed when a familiar event is paired with a new outcome, compared to the association of an unfamiliar event. LI is a process that is often disrupted in individuals with schizophrenia and is known as a cognitive symptom. This study aimed to determine whether the drug WIN-55-212-2 (WIN), which interacts with the ECS, influences the process of LI using a fear-conditioned response procedure. The results found no significant interaction among …

Glucagon-Like Peptide-1ra As A Public Health Interventions, Briana Sepeda

Electronic Theses, Projects, and Dissertations

Glucagon-like peptide receptor agonist (GLP-1RA) medications have become a prominent topic of interest both in clinical medicine and broader societal discussions. Although the medication are relatively new and expensive, ongoing research continues to explore pharmacologic modifications aimed at improving therapeutic effectiveness and prolonged drug half-life. GLP-1RAs have gained significant traction due to their ability to lower glycosylated hemoglobin (A1c) and blood glucose levels in individuals who have been diagnosed with type 2 diabetes (T2D). In addition to glycemic control, evidence suggests its associations with appetite suppression, weight loss, reducing cardiovascular disease, improved renal dysfunction, neuroprotective effects related to neurodegenerative disease …

Commodified Suffering: True Crime Podcasting, Gendered Violence, And The Culture Of Apathy”, Alaysia Lewis

All Theses

This study examines the linguistic patterns of true crime podcast hosts, as well as what potential impacts these language choices have on audiences. Through an analysis of literature regarding true crime media, listener motivations, and the effects of true crime media consumption on listeners, themes of apathy and desensitization, female pain as entertainment, and commodification of harm against women were found. This serves as a case study of the popular true crime podcast Crime Junkie, observing the language patterns used by the hosts before and after their involvement in a controversy that included accusations of plagiarism, commodification, and unethical journalistic …

An Appalachian Approach To Urban Flooding In South Carolina, North Carolina, And Kentucky, Boyce A. Clardy Iii

All Theses

Urban flooding poses an ever-growing threat to the built environment worldwide, as it is the leading natural hazard contributing to fatalities globally. Planners stand in a unique position to produce plans and policies that reflect and combat this threat, yet the capacity and obligation to do so varies considerably depending on where a community sits within the broader legislative and institutional landscape. This thesis focuses on the Southeastern subregion of Appalachia, a part of the United States characterized by mountainous terrain, steep foothills, and narrow valley communities. This region was chosen as much attention in the broader literature is focused …

Between Chronicle And Legend: A Two-Scene Environment And Visual Effects Examination Of Physical Accuracy And Emotional Exaggeration On The Honey Creek Bridge Collapse, Alison R. Gaddy

All Theses

This thesis explores how truth and dramatization intersect in digital storytelling by comparing realistic and stylized simulations of the Honey Creek bridge collapse within the context of the Kate Shelley animated short. At the core of storytelling lies a tension between factual accuracy and dramatic stylization. We investigate that tension by examining how narrative truth is conveyed, distorted, or enhanced through visual dramatization by focusing on the psychology of audience perception and the motivations behind creative embellishment. The practical contribution of this research is the development of two distinct digital scene setups depicting the same Honey Creek bridge collapse event. …

Romanticizing 'Monsters': Sexualized Digital Fandom Of The Menendez Brothers, Kimberly M. Brooks

All Theses

This study was conducted to explore the expressions of sexualized fandom and parasocial relationships within the context of true crime. The Menendez Brothers were chosen as the case to focus on due to the Netflix dramatization ‘Monsters: The Lyle and Erik Menendez Story’ release and online popularity. Reddit was the platform chosen for data collection because of the longstanding presence of true crime followers participating in dialogue on the platform. The r/MenendezBrothers thread was chosen to collect data from because of its large following and large number of weekly contributions. Sprinklr, the social media analytics platform, was employed to gather …

Fluorescence-Based Quantification Of Hepatic Ldl Uptake And Donor Hepatocyte Engraftment Using Atto 700–Labeled Ldl, Victor Agustin Cortes Flores

All Theses

Familial hypercholesterolemia (FH) is an inherited disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C) that increases the risk of premature atherosclerotic cardiovascular disease. In severe FH, including low-density lipoprotein receptor (LDLR), hepatic LDL clearance is profoundly impaired and many lipid lowering treatment strategies have limited effectiveness. Current advances in ex vivo CRISPR–Cas9 hepatocyte gene editing in vivo and ex vivo approaches for treatment of FH are under development.

However, a central barrier to translation is the ability to quantitatively measure the percentage of healthy gen edited hepatocytes in the liver while simultaneously assessing functional hepatic LDL handling. This thesis establishes …

“Tyranny” As Concept: Semantic Change And The Formation Of Colonial Political Consciousness In The New Hampshire Gazette, 1756–1783, Antonio Worley

All Theses

Historians of the American Revolution have frequently viewed terms such as tyranny as a stable ideological category, associated with corruption and resistance to arbitrary power. This thesis instead reconceptualizes ‘tyranny’ as an evolving and historically contingent Koselleckian concept. Drawing on a comprehensive analysis of the New Hampshire Gazette from 1756 to 1783, this study combines close reading with computational methods, including word frequency analysis and word embeddings, to chart the evolution of the semantic field surrounding “tyranny” over time.

Prior to the Stamp Act of 1765, ‘tyranny’ was used primarily in a religious and moral framework which was shaped by …

Portrayals Of Miscarriage In Film And Television: A Qualitative Analysis, Geovana Leonetti Saraiva

All Theses

Entertainment media may serve as a primary source through which individuals learn about miscarriage; however, little research has examined how miscarriage is portrayed in film and television. This study addresses this gap by conducting a textual analysis of five films and five television shows using a constructivist grounded theory approach. Guided by the model of stigma communication (MSC), communication privacy management theory (CPM), and social support frameworks, the analysis explores how miscarriage is represented in entertainment media.

Findings indicate that the analyzed content frequently includes stigma-related cues—such as marks, labels, responsibility, and peril—that may contribute to the formation and reinforcement …