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Navigating The Ethical Terrain Of Ai In Higher Education: Strategies For Mitigating Bias And Promoting Fairness, Emily Barnes, James Hutson Jun 2024

Navigating The Ethical Terrain Of Ai In Higher Education: Strategies For Mitigating Bias And Promoting Fairness, Emily Barnes, James Hutson

Faculty Scholarship

Artificial intelligence (AI) and machine learning (ML) are transforming higher education by enhancing personalized learning and academic support, yet they pose significant ethical challenges, particularly in terms of inherent biases. This review critically examines the integration of AI in higher education, underscoring the dual aspects of its potential to innovate educational paradigms and the essential need to address ethical implications to avoid perpetuating existing inequalities. The researchers employed a methodological approach that analyzed case studies and literature as primary data collection methods, focusing on strategies to mitigate biases through technical solutions, diverse datasets, and strict adherence to ethical guidelines. Their …


It’S Not A Few, It’S All: How Political Elites Create And Construct The Meaning Of Terrorism And Apply It To An Entire Group, Jamarne Mcgill Jun 2024

It’S Not A Few, It’S All: How Political Elites Create And Construct The Meaning Of Terrorism And Apply It To An Entire Group, Jamarne Mcgill

Publications and Research

In the aftermath of the September 11th terror attacks, we witnessed political elites make adequate use of coded language in order to justify the implementation of an aggressive and punitive foreign policy in the Middle East. Terror attacks are disruptive, catastrophic events that tend to produce feelings of racial resentment and a desire for collective punishment toward an entire group of people. Although the perpetrators of a terror attack do not represent or speak for the majority of a much larger group, the general population of the nation or state that was attacked may not feel this way. Therefore, an …


Symposium Introduction: Challenge And Hope, Frank A. Fritz, Kyle-Matthew Taylor Jun 2024

Symposium Introduction: Challenge And Hope, Frank A. Fritz, Kyle-Matthew Taylor

Nevada Law Journal

No abstract provided.


Sacrifice Zones, Jonathan Rosenbloom Jun 2024

Sacrifice Zones, Jonathan Rosenbloom

Nevada Law Journal

No abstract provided.


The Lawyer's Duty Of Competence In A Climate-Imperiled World, John C. Dernbach, Irma S. Russell, Matthew Bogoshian Jun 2024

The Lawyer's Duty Of Competence In A Climate-Imperiled World, John C. Dernbach, Irma S. Russell, Matthew Bogoshian

UMKC Law Review

The United States has more than 1.3 million practicing lawyers. Under Model Rule 1.1 of the ABA Model Rules of Professional Conduct and every state’s rules of conduct, each of these lawyers owes clients competent representation. Under the rule, “[c]ompetent representation requires the knowledge, skill, thoroughness and preparation reasonably necessary for the services.” While law and rules will undoubtedly change in response to the climate crisis, the duty of competence does not await such change or legal reform. The ubiquitous nature of the duty of competence means it is applicable to each lawyer now and will continue to evolve as …


Regulating Forever?: The Epa's Goal To Remediate Forever Chemicals Already In The Environment Under The Safe Drinking Water Act, Anna Donaldson Jun 2024

Regulating Forever?: The Epa's Goal To Remediate Forever Chemicals Already In The Environment Under The Safe Drinking Water Act, Anna Donaldson

UMKC Law Review

No abstract provided.


Past * An Introduction To The Problem, Zelimir Zilnik, Boris Buden, New Media Center Kuda.Org, Olivera Jokic Jun 2024

Past * An Introduction To The Problem, Zelimir Zilnik, Boris Buden, New Media Center Kuda.Org, Olivera Jokic

Publications and Research

Who can know what is in the past? Is it what historians can tell us? Should we also trust what we can remember? Past • An Introduction to the Problem proposes that the problem of the past now concerns everyone. Visions of a different, brighter future defeated in the Cold War and its heated afterlives, we are being offered the past as the only horizon of possibility. And what are we supposed to find in that past? Philosopher Boris Buden considers these questions in a series of essays and conversations with filmmaker Želimir Žilnik, one of the most prominent filmmakers …


Selection Of Host Plants For Production Of Clanis Bilineata (Lepidoptera: Sphingidae), Xiaofeng Li, Mingming Guo, Kebin Li, Song Li, Honglin Feng, Jiwei Fan Jun 2024

Selection Of Host Plants For Production Of Clanis Bilineata (Lepidoptera: Sphingidae), Xiaofeng Li, Mingming Guo, Kebin Li, Song Li, Honglin Feng, Jiwei Fan

Faculty Publications

Clanis bilineata Walker (Lepidoptera: Sphingidae), a burgeoning edible insect, is experiencing rising demand in China and other regions. Despite this interest, larval production is currently constrained by the limitations of artificial production technologies, particularly the selection of optimal host plants. This study rigorously evaluated the performance of C. bilineatha larvae on four main host plants: round-leaf soybean, pointed-leaf soybean, black locust, and kudzu. Preference tests demonstrated that the larvae were most attracted to black locust (34.76 ± 4.65%), with subsequent preferences for kudzu (25.00 ± 6.12%), round-leaf soybean (23.17 ± 2.79%), and pointed-leaf soybean (14.02 ± 4.74%). No significant preference …


Inhalation Of Particulate Matter Containing Environmentally Persistent Free Radicals Induces Endothelial Dysfunction Mediated Via Ahr Activation At The Air-Blood Interface, Ankit Aryal, Ashlyn C. Harmon, Kurt J. Varner, Alexandra Noël, Stephania A. Cormier, Divine B. Nde, Peter Mottram, Jemiah Maxie, Tammy R. Dugas Jun 2024

Inhalation Of Particulate Matter Containing Environmentally Persistent Free Radicals Induces Endothelial Dysfunction Mediated Via Ahr Activation At The Air-Blood Interface, Ankit Aryal, Ashlyn C. Harmon, Kurt J. Varner, Alexandra Noël, Stephania A. Cormier, Divine B. Nde, Peter Mottram, Jemiah Maxie, Tammy R. Dugas

Division of Basic Science Faculty Publications

Particulate matter (PM) containing environmentally persistent free radicals (EPFR) is formed by the incomplete combustion of organic wastes, resulting in the chemisorption of pollutants to the surface of PM containing redox-Active transition metals. In prior studies in mice, EPFR inhalation impaired endothelium-dependent vasodilation. These findings were associated with aryl hydrocarbon receptor (AhR) activation in the alveolar type-II (AT-II) cells that form the air-blood interface in the lung. We thus hypothesized that AhR activation in AT-II cells promotes the systemic release of mediators that promote endothelium dysfunction peripheral to the lung. To test our hypothesis, we knocked down AhR in AT-II …


Estrogen Counteracts Age-Related Decline In Beige Adipogenesis Through The Nampt-Regulated Er Stress Response, Jooman Park, Ruoci Hu, Yanyu Qian, Shaolei Xiong, Asma Sana El-Sabbagh, Meram Ibrahim, Jaden Wang, Ziqiao Xu, Zhengjia Chen, Qing Song, Zhenyuan Song, Gege Yan, Abeer M. Mahmoud, Yanlin He, Brian T. Layden, Jiwang Chen, Sang Ging Ong, Pingwen Xu, Yuwei Jiang Jun 2024

Estrogen Counteracts Age-Related Decline In Beige Adipogenesis Through The Nampt-Regulated Er Stress Response, Jooman Park, Ruoci Hu, Yanyu Qian, Shaolei Xiong, Asma Sana El-Sabbagh, Meram Ibrahim, Jaden Wang, Ziqiao Xu, Zhengjia Chen, Qing Song, Zhenyuan Song, Gege Yan, Abeer M. Mahmoud, Yanlin He, Brian T. Layden, Jiwang Chen, Sang Ging Ong, Pingwen Xu, Yuwei Jiang

Division of Basic Science Faculty Publications

Thermogenic beige adipocytes are recognized as potential therapeutic targets for combating metabolic diseases. However, the metabolic advantages that they offer are compromised with aging. Here we show that treating mice with estrogen (E2), a hormone that decreases with age, can counteract the age-related decline in beige adipogenesis when exposed to cold temperature while concurrently enhancing energy expenditure and improving glucose tolerance in mice. Mechanistically, we found that nicotinamide phosphoribosyl transferase (NAMPT) plays a pivotal role in facilitating the formation of E2-induced beige adipocytes, which subsequently suppresses the onset of age-related endoplasmic reticulum (ER) stress. Furthermore, we found that targeting NAMPT …


Accelerated Onset Of Diabetes In Non-Obese Diabetic Mice Fed A Refined High-Fat Diet, Heidi M. Batdorf, Luz De Luna Lawes, Gabrielle A. Cassagne, Molly S. Fontenot, Innocence C. Harvey, Jeremy T. Richardson, David H. Burk, Samuel D. Dupuy, Michael D. Karlstad, J. Michael Salbaum, Jaroslaw Staszkiewicz, Robbie Beyl, Sujoy Ghosh, Susan J. Burke, J. Jason Collier Jun 2024

Accelerated Onset Of Diabetes In Non-Obese Diabetic Mice Fed A Refined High-Fat Diet, Heidi M. Batdorf, Luz De Luna Lawes, Gabrielle A. Cassagne, Molly S. Fontenot, Innocence C. Harvey, Jeremy T. Richardson, David H. Burk, Samuel D. Dupuy, Michael D. Karlstad, J. Michael Salbaum, Jaroslaw Staszkiewicz, Robbie Beyl, Sujoy Ghosh, Susan J. Burke, J. Jason Collier

Division of Basic Science Faculty Publications

Aim: Type 1 diabetes results from autoimmune events influenced by environmental variables, including changes in diet. This study investigated how feeding refined versus unrefined (aka ‘chow’) diets affects the onset and progression of hyperglycaemia in non-obese diabetic (NOD) mice. Methods: Female NOD mice were fed either unrefined diets or matched refined low- and high-fat diets. The onset of hyperglycaemia, glucose tolerance, food intake, energy expenditure, circulating insulin, liver gene expression and microbiome changes were measured for each dietary group. Results: NOD mice consuming unrefined (chow) diets developed hyperglycaemia at similar frequencies. By contrast, mice consuming the defined high-fat diet had …


Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev Jun 2024

Effect Of Long-Term Caloric Restriction On Telomere Length In Healthy Adults: Calerie™ 2 Trial Analysis, Waylon J. Hastings, Qiaofeng Ye, Sarah E. Wolf, Calen P. Ryan, Sai Krupa Das, Kim M. Huffman, Michael S. Kobor, William E. Kraus, Julia L. Macisaac, Corby K. Martin, Susan B. Racette, Leanne M. Redman, Daniel W. Belsky, Idan Shalev

Clinical Research Faculty Publications

Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE™) 2 trial tested translation of these findings to humans. CALERIE™ randomized healthy, nonobese men and premenopausal women (age 21–50y; BMI 22.0–27.9 kg/m2), to 25% CR or ad-libitum (AL) control (2:1) for 2 years. Prior analyses of CALERIE™ participants' blood chemistries, immunology, and epigenetic data suggest the 2-year CR intervention slowed biological aging. Here, we extend these analyses to test effects of CR on telomere length (TL) attrition. TL was quantified in blood samples collected at baseline, 12-, …


Assessing The Long-Term Effects Of Conservation Agriculture On Cotton Production In Northeast Louisiana Using The Denitrification–Decomposition Model, Janntul Ferdush, Changyoon Jeong, Hwangju Jeon, Jim Wang, Kyoung Ro, Xi Zhang, Meesook Lee Jun 2024

Assessing The Long-Term Effects Of Conservation Agriculture On Cotton Production In Northeast Louisiana Using The Denitrification–Decomposition Model, Janntul Ferdush, Changyoon Jeong, Hwangju Jeon, Jim Wang, Kyoung Ro, Xi Zhang, Meesook Lee

Faculty Publications

Conservation agriculture (CA) aims to sustain agricultural production, soil, and environmental health in agroecosystems and has been promoted throughout the United States. The adoption of CA in cotton (Gossypium hirsutum) systems provides both agronomic and environmental benefits. Yet, there is limited information on the long-term effects of CA practices on crop yield and adaptation strategies. An integrated CA system, that is, cover crops with no-tillage (NT) instead of conventional agriculture, was implemented in the long-term field experiments and assessed with an integrated biogeochemical model. Using the denitrification–decomposition model, this study estimated the effects of four different cover crops, for example, …


Aspen As Firebreaks At The Development Fringe, Kevin Krasnow, Paul C. Rogers Jun 2024

Aspen As Firebreaks At The Development Fringe, Kevin Krasnow, Paul C. Rogers

Aspen Bibliography

Quaking aspen (Populus tremuloides) forests are widely known and prized for their numerous values—biodiversity, habitat, forage, recreation, aesthetics, and others—including as a deterrent to wildfire. This reputation for stopping or slowing flames is explored here, alongside measures that may be taken to facilitate thriving aspen communities near human developments. It is clear that science supporting the premise of aspen as an effective firebreak is far from complete. Yet, how can we benefit from what we do know on this topic to increase the probability of preventing structural fire damage, while also encouraging the valued characteristics of aspen ecosystems?


Climate Considerations For Quaking Aspen Conservation, Douglas Shinneman, Susan Mcilroy, Paul C. Rogers Jun 2024

Climate Considerations For Quaking Aspen Conservation, Douglas Shinneman, Susan Mcilroy, Paul C. Rogers

Aspen Bibliography

Human-caused climate change alters ecosystem processes ranging from local to global scales. As a consequence of climate change we should expect increased rates and intensities of disturbance events. Though we are only beginning to understand what those impacts might be to aspen forests and their diverse plant and animal assemblages, recent science suggests there may be unavoidable effects. In the face of anticipated climate-ecosystem challenges, contemporary managers are searching for guidance on preserving aspen resilience. We suggest crafting strategic yet cautious approaches to minimize effects and facilitate broad resilience. For instance, monitoring conditions in and near aspen forests will help …


Fisheries Occasional Publication No.147 - Aquaculture Development Zones – Policy Position Relating To Permitted Alternative Species, Department Of Primary Industries And Regional Development, Western Australia Jun 2024

Fisheries Occasional Publication No.147 - Aquaculture Development Zones – Policy Position Relating To Permitted Alternative Species, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Occasional Publications

The purpose of this policy is to set out considerations relevant to the assessment of aquaculture proposals within Aquaculture Development Zones (ADZ) for species distinct from the group of species for which the ADZ was initially established (Alternative Species).


Short-Term Response Of Soil Microbial Community And Soil Bio-Chemical Properties To Soybean Intercropping In A Cassava-Based Cropping System, Nolissa Organo, John Lester Pide, Michelle Anne Calubaquib, Elmer Enicola, Evelyn Delfin, Vanessa Calderon, Raymund Antiola, Hosne Dilzahan, Andre Cruz Jun 2024

Short-Term Response Of Soil Microbial Community And Soil Bio-Chemical Properties To Soybean Intercropping In A Cassava-Based Cropping System, Nolissa Organo, John Lester Pide, Michelle Anne Calubaquib, Elmer Enicola, Evelyn Delfin, Vanessa Calderon, Raymund Antiola, Hosne Dilzahan, Andre Cruz

The Philippine Agricultural Scientist

A cassava-based cropping system study assessed the short-term response of soil chemical and biochemical properties and soil microbial communities to soybean intercropping. Two soybean varieties (‘Select Manchuria’ and ‘Tiwala 12’) were tested as intercrops. The treatments did not affect the soil’s chemical (pH, OM, N, P, K) and biochemical (basal respiration and dehydrogenase and urease enzyme activities) properties after one cropping period. Amplicon sequencing analysis found that intercropping promoted the abundance of bacterial orders Actinomycetales, Solibacterales, Sphingomonadales, and Rhodospirillales. These groups play active roles in organic matter decomposition and can potentially improve the soil quality in an area by enhancing …


Simulated Transport Of Silver Therapon (Leiopotherapon Plumbeus) Fingerlings At Different Durations And Loading Densities: Effects On Survival And Water Quality, Frolan A. Aya, Reylan C. Gutierrez, Luis Maria Garcia Jun 2024

Simulated Transport Of Silver Therapon (Leiopotherapon Plumbeus) Fingerlings At Different Durations And Loading Densities: Effects On Survival And Water Quality, Frolan A. Aya, Reylan C. Gutierrez, Luis Maria Garcia

The Philippine Agricultural Scientist

The silver therapon, Leiopotherapon plumbeus, is a new species for aquaculture. However, information on the optimal conditions for the transport of this species for grow-out culture needs to be established to avoid stress and unnecessary mortalities. This study examined the effects of duration of transport and loading density on survival and water quality during simulated transport of silver therapon. Hatchery-produced fingerlings [1.30 ± 0.34 g body weight (BW); 44.30 ± 3.77 mm total length (TL)] were held in double-layered oxygenated plastic bags at three transport durations (6 h, 9 h, and 12 h) and densities (40, 80, and 120 …


Microbiological And Physicochemical Changes In Rabbit Meat During Ambient Storage, Marielle Gamboa, Dennis Marvin Santiago, April Shayne Sulabo, Mary Ann Torio Jun 2024

Microbiological And Physicochemical Changes In Rabbit Meat During Ambient Storage, Marielle Gamboa, Dennis Marvin Santiago, April Shayne Sulabo, Mary Ann Torio

The Philippine Agricultural Scientist

This study aimed to evaluate the changes in rabbit meat during storage at ambient temperature (30 ± 1ºC) for nine hours. The study focused on two rabbit muscle parts: the hind leg and the saddle, investigated in terms of microbiological parameters such as aerobic plate count (APC) and total coliform count (TCC); and physicochemical parameters such as pH, color, total myoglobin concentration, and lipid oxidation. Data obtained were subjected to statistical analysis at a 5% significance level (p < 0.05). Results revealed that the pH of both portions of rabbit muscle decreases over time during storage. This decrease is attributed to the growth of acid-producing microorganisms, which ultimately leads to spoilage in rabbit meat. On the contrary, color values (L*, a*, and b*) showed an increasing trend in both muscle portions, indicating a discoloration of rabbit meat during storage. Both lipid oxidation and total myoglobin content of rabbit meat did not change significantly during storage, but lipid oxidation varied between muscle parts. Based on the microbiological analysis of rabbit meat, both aerobic plate count (APC) and total coliform count (TCC) increased significantly during storage in both muscle portions. Results of the study suggest that freshly slaughtered rabbit meat must remain at ambient storage for the shortest time, as this storage condition will cause spoilage of meat, making it unfit for human consumption.


Isolation And Identification Of Entomopathogenic Fungi From The Soils Of Northwest Iran And Their Biological Control Efficacy On The Flour Moth (Ephestia Kuehniella) [Research Note], Mohadeseh Moghasem, Manizheh Jamshidi, Reza Khakvar, Sevil Nematollahi Jun 2024

Isolation And Identification Of Entomopathogenic Fungi From The Soils Of Northwest Iran And Their Biological Control Efficacy On The Flour Moth (Ephestia Kuehniella) [Research Note], Mohadeseh Moghasem, Manizheh Jamshidi, Reza Khakvar, Sevil Nematollahi

The Philippine Agricultural Scientist

Entomopathogenic fungi have the potential to serve as alternatives to or supplements for chemical pesticides in insect biocontrol, with many of these fungi being utilized in commercial and integrated pest control practices globally. This study aimed to isolate and evaluate the efficacy of various entomopathogenic fungi for the biocontrol of the flour moth, Ephestia kuehniella (Lep: Pyralidae). Multiple isolates of entomopathogenic fungi were acquired from soils across different districts of Azerbaijan province in northwest Iran, and their virulence against E. kuehniella larvae was assessed. Seventeen isolates representing diverse entomopathogenic fungi were isolated and purified using the soil trap method from …


Genetic Approaches To Improving Coffee Resistance Against Diseases And Pests In The Philippines [Review Paper], Nick Rainier Santos, Ernelea Cao, Daisy May Santos Jun 2024

Genetic Approaches To Improving Coffee Resistance Against Diseases And Pests In The Philippines [Review Paper], Nick Rainier Santos, Ernelea Cao, Daisy May Santos

The Philippine Agricultural Scientist

There is a huge demand for coffee in the Philippines but local supply has a long way to go at catching up. One way to aid local farmers is to develop coffee varieties with combined desirable traits including natural resistance against various diseases and insect pests. This can increase product output and reduce costs on chemical control that can, in turn, potentially increase their profits. This paper reviews and gives an overview of the genetic research on coffee toward improving plant defense. The most prominent diseases and pests plaguing plantations worldwide are noted. From studies using classical tools such as …


Reversal Of Propofol-Induced Depression Of The Hypoxic Ventilatory Response By Bk-Channel Blocker Ena-001: A Randomized Controlled Trial, Simone Jansen, Maarten Van Lemmen, Erik Olofsen, Laurence Moss, Joseph Pergolizzi, Thomas Miller, Robert Colucci, Monique Van Velzen, Philip Kremer, Albert Dahan, Rutger Van Der Schrier, Marieke Niesters Jun 2024

Reversal Of Propofol-Induced Depression Of The Hypoxic Ventilatory Response By Bk-Channel Blocker Ena-001: A Randomized Controlled Trial, Simone Jansen, Maarten Van Lemmen, Erik Olofsen, Laurence Moss, Joseph Pergolizzi, Thomas Miller, Robert Colucci, Monique Van Velzen, Philip Kremer, Albert Dahan, Rutger Van Der Schrier, Marieke Niesters

Department of Medicine Faculty Papers

BACKGROUND: The use of anesthetics may result in depression of the hypoxic ventilatory response. Since there are no receptor-specific antagonists for most anesthetics, there is the need for agnostic respiratory stimulants that increase respiratory drive irrespective of its cause. The authors tested whether ENA-001, an agnostic respiratory stimulant that blocks carotid body BK-channels, could restore the hypoxic ventilatory response during propofol infusion. They hypothesize that ENA-001 is able to fully restore the hypoxic ventilatory response.

METHODS: In this randomized, double-blind crossover trial, 14 male and female healthy volunteers were randomized to receive placebo and low- and high-dose ENA-001 on three …


Using Knowledge Of Human Factors To Strengthen Highway Design, Chris Van Dyke, Jeff Jasper, Jill Asher, Steve Waddle Jun 2024

Using Knowledge Of Human Factors To Strengthen Highway Design, Chris Van Dyke, Jeff Jasper, Jill Asher, Steve Waddle

Kentucky Transportation Center Research Report

Transportation practitioners recognize that leveraging knowledge of human factors in road design is critical for delivering safe mobility to the full spectrum of multimodal road users (motorists, pedestrians, micromobility users, transit users). Understanding how psychology, cognition, and behavioral tendencies shape the ways in which different road users interact with one another and the road environment itself is critical for creating design solutions that promote safe and efficient movement. NCHRP Report 600 (Human Factors Guidelines for Road Systems) provides guidance on integrating knowledge of human factors into design practice. While the report is a valuable resource, it appears to …


Aerobic Exercise Improves Depressive Symptoms In The Unilateral 6-Ohda-Lesioned Rat Model Of Parkinson's Disease, Hannah Loughlin, Jacob Jackson, Chloe Looman, Alayna Starll, Jeremy Goldman, Zhiying Shan, Chunxiu Yu Jun 2024

Aerobic Exercise Improves Depressive Symptoms In The Unilateral 6-Ohda-Lesioned Rat Model Of Parkinson's Disease, Hannah Loughlin, Jacob Jackson, Chloe Looman, Alayna Starll, Jeremy Goldman, Zhiying Shan, Chunxiu Yu

Michigan Tech Publications

Aerobic exercise has been shown to have established benefits on motor function in Parkinson's disease (PD). However, the impact of exercise on depressive symptoms in PD remains unclear. This study aimed to investigate the effects of regular exercise, specifically using a forced running wheel, on both motor performance and the prevalence of depression in a unilateral 6-OHDA-lesioned rat model of PD. The behavioral outcomes of exercise were assessed through the rotarod test (RT), forelimb adjusting step test (FAST), sucrose consumption test (SCT), and novelty sucrose splash test (NSST). Our data revealed evident depressive symptoms in the PD animals, characterized by …


The Inhibition Of Sars-Cov-2 Papain-Like Protease By Tanshinones, Alex Beringer Jun 2024

The Inhibition Of Sars-Cov-2 Papain-Like Protease By Tanshinones, Alex Beringer

PCOM Biomedical Studies Student Scholarship

The emergence of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has highlighted the critical need for effective antiviral treatments. Three significant coronaviruses—SARS-CoV-1, MERS-CoV, and SARS-CoV-2—have posed serious global health threats in the past two decades. Among them, SARS-CoV-2 has demonstrated the highest transmission and mortality rates, underscoring the urgency for innovative therapeutic strategies. This study delves into the potential of tanshinones, natural compounds derived from Salvia miltiorrhiza, as inhibitors of the SARS-CoV-2 PLpro enzyme. PLpro is a pivotal enzyme in the viral replication and an attractive target for antiviral drug development. By inhibiting PLpro, tanshinones may hinder viral replication …


Preliminaries Jun 2024

Preliminaries

Journal of English and Applied Linguistics

Abstract not applicable.


Investigating Attitudes, Perceptions, And Challenges Of Moroccan Efl Teachers' Incorporation Of Critical Thinking In Argumentative Writing Instructions, Abdelmomen Khalil, Nadia Hellalet Jun 2024

Investigating Attitudes, Perceptions, And Challenges Of Moroccan Efl Teachers' Incorporation Of Critical Thinking In Argumentative Writing Instructions, Abdelmomen Khalil, Nadia Hellalet

Journal of English and Applied Linguistics

This study aimed at finding out Moroccan English as a foreign language (EFL) high school teachers’ attitudes towards incorporating critical thinking skills (CTS) in their teaching practices and in argumentative writing in particular, how they facilitate CTS, and what challenges they experience when incorporating CTS. To fulfill the research objectives and collect both quantitative and qualitative data, a mixed-methods approach was adopted using questionnaires and interviews. The researchers collected data from 127 EFL teachers from different Moroccan high schools. The findings revealed that the teachers hold positive attitudes toward critical thinking (CT) and integrating it in their argumentative writing instructions. …


Reconceiving Corporate Rights And Regulation In The Ai Era, Michael R. Siebecker Jun 2024

Reconceiving Corporate Rights And Regulation In The Ai Era, Michael R. Siebecker

Missouri Law Review

Can existing corporate governance principles properly guide the relationship between shareholders and directors as artificial intelligence (“AI”) plays an increasingly prominent role in corporate management, planning, and operations? Without a doubt, AI technologies allow corporations to enjoy enhanced efficiency and innovation. But the vast range of AI capabilities—from sophisticated data analytics to autonomous decision-making—raises profound questions about whether traditional governance principles remain sufficiently robust to cabin the proper development and deployment of such a powerful and rapidly evolving set of new technologies. Current corporate governance structures that focus on human actors and traditional business decision-making mechanisms seem ill-suited to address …


The Penal Judgment Exception To Full Faith And Credit: How To Bind The Bounty Laws, Walker Mckusick Jun 2024

The Penal Judgment Exception To Full Faith And Credit: How To Bind The Bounty Laws, Walker Mckusick

Washington Law Review

In the current moment of interstate friction over abortion, the penal judgment exception poses a barrier against interstate enforcement of bounty laws. A doctor who prescribes a medicated abortion to a Texas patient may be exposed to civil liability—even in faraway Washington State. A Washington court asked to enforce a Texas judgment against the doctor is subject to the Full Faith and Credit Clause. Article IV, Section 1 of the United States Constitution mandates that each state give full faith and credit to judgments rendered in sister states. Under Texas Senate Bill 8 (S.B. 8), any member of the public …


The Best Children's Books Of 2024: Summer Reading Guide, Bank Street College Of Education. Children's Book Committee. Jun 2024

The Best Children's Books Of 2024: Summer Reading Guide, Bank Street College Of Education. Children's Book Committee.

Children's Book Committee

Notable titles that have captured the attention of our members as well as experts in the field of children’s literature, such as librarians, authors, teachers, psychologists, and editors. This is the perfect place to find a book that will delight young readers during the long days of summer.