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The Brainstem As A Conserved System For Consciousness: Integrating Phylogeny, Neurology, And Psychology, Shadia Kawkabani, Kevin P. Kaut

Journal of Neuropsychology and Behavioral Processes

Historically, scientists and physicians have taken a corticocentric view of consciousness, emphasizing the need for a cortex in producing the conscious experience. The preserved consciousness observed in hydranencephalic children and decorticated rats suggests that some form of consciousness may be produced by a subcortical network. The brainstem, a phylogenetically conserved brain system, could serve as the major integrative network to produce this form of consciousness—referred to as ‘affective consciousness’, the evolutionary antecedent to the reflective consciousness allowing humans to reflect on experiences. The functional integration of the brainstem with the amygdala, motor network, and other subcortical structures provides the architecture …

Controversy In Consciousness: Is The Brainstem Sufficient For Sentience?, Shadia Kawkabani, Kevin P. Kaut

Journal of Neuropsychology and Behavioral Processes

Our understanding of consciousness is quite possibly in need of further discussion, elaboration, and updating. What was once principally the domain of philosophical inquiry has entered the era of advanced research methods and biomedical ethics – both of which have influenced the need to reconsider this most challenging of topics. The challenge for those interested in consciousness is at least twofold: 1) to further operationally define what is meant by consciousness, with a greater understanding of how consciousness can be manifest, and 2) to better identify the neural mechanisms subserving the diverse presentations/manifestations of consciousness, and reconcile the developing literatures …

Phototaxis In The Terrestrial Isopod: A Mechanism For Investigating Invertebrate Learning And Memory, Christopher Buzzelli, Jessica Kent, Chelsea Pawlak, Kevin P. Kaut

Journal of Neuropsychology and Behavioral Processes

Isopods readily explore new environments and typically prefer contexts with lower levels of illumination (i.e., negative phototaxis). In the first of two behavioral experiments reported here, the ability of isopods to discriminate between light and dark nesting regions was confirmed, although evidence suggests an initial ‘instinctive’ draw toward a darker context. Extending these findings to experiment 2, isopods were trained against their negatively phototaxic tendency and had to exit a darkened start chamber in order to locate nesting material in a brighter chamber. Within-session improvements in latency to enter the nesting region were noted across training trials, coupled with evidence …

Is The Use Of Artificial Intelligence In Alternative Dispute Resolution A Viable Option Or Wishful Thinking?, Samuel D. Hodge Jr.

Pepperdine Dispute Resolution Law Journal

This article delves into the evolving relationship between artificial intelligence (AI) and the legal profession, particularly in the context of alternative dispute resolution (ADR). The introduction sets the stage by highlighting AI's transformative potential in reshaping legal practice through automation, efficiency, and data-driven insights. While acknowledging the uncertainty surrounding AI's long-term impact on the legal landscape, it emphasizes the need for investigation and adaptation as the technology evolves. Key considerations, such as AI technology's limitations, regulatory challenges, and ethical implications, are also addressed. Despite the promises of efficiency and accessibility, questions remain about AI's ability to replicate human reasoning and …

Noda News February 2013

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

Noda News November 2022

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

Who Should Be Liable? Examining The Corporate Liability Regime For Cybersecurity Risks, Angel R. Gardner

Student Journal of Information Privacy Law

The growth of the Internet of Things (IoT) poses new and substantial security risks for individual and national security. The IoT leaves networks susceptible to hacking, a form of unauthorized access into another person’s system or device. All devices that use the IoT are at risk of unauthorized access—a few examples include vehicles or medical devices. Currently, there are no regulations requiring corporations to protect their software from unauthorized intrusions. However, the current tort landscape does not allow for individuals to recover when there are unauthorized network intrusions where there is no tangible harm. This paper discusses why cybersecurity intrusions …

Distinct Expression Patterns Of Hedgehog Signaling Components In Mouse Gustatory System During Postnatal Tongue Development And Adult Homeostasis, Archana Kumari, Nicole E Franks, Libo Li, Gabrielle Audu, Sarah Liskowicz, John D Johnson, Charlotte M Mistretta, Benjamin L Allen

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The Hedgehog (HH) pathway regulates embryonic development of anterior tongue taste fungiform papilla (FP) and the posterior circumvallate (CVP) and foliate (FOP) taste papillae. HH signaling also mediates taste organ maintenance and regeneration in adults. However, there are knowledge gaps in HH pathway component expression during postnatal taste organ differentiation and maturation. Importantly, the HH transcriptional effectors GLI1, GLI2 and GLI3 have not been investigated in early postnatal stages; the HH receptors PTCH1, GAS1, CDON and HHIP, required to either drive HH pathway activation or antagonism, also remain unexplored. Using lacZ reporter mouse models, we mapped expression of the HH …

2024-06-07 Minutes & Appendices, Longwood University

Board of Visitors Meeting Minutes 1964-

No abstract provided.

Malnutrition Alters Protein Expression Of Kndy Neuropeptides In The Arcuate Nucleus Of Mature Ewes, Jennifer F. Thorson, Ligia D. Prezotto

Department of Animal Science: Faculty Publications

The neuropeptides kisspeptin, neurokinin B, and dynorphin A are imperative for the pulsatile secretion of gonadotropin-releasing hormone and luteinizing hormone to ultimately regulate reproductive cyclicity. A population of neurons co-expressing these neuropeptides, KNDy neurons, within the arcuate nucleus of the hypothalamus (ARC) are positioned to integrate energy status from afferent neuronal and glial cells. We hypothesized that KNDyexpressing neurons in the ARC of mature ewes are influenced by energy balance. To test this hypothesis, ovary-intact, mature ewes were fed to lose, maintain, or gain body weight and hypothalamic tissue harvested during the luteal phase of the estrous cycle. Fluorescent, multiplex …

Artificial Intelligence As The Next Front In The Class War, Christopher Hill

Dissertations and Theses

For many years, artificial intelligence has been confined to the realm of science fiction, and while the technology has been in development, predicting the effects AI will have on our society has been a challenging endeavor. The release of ChatGPT in 2022, the subsequent mass adoption of the AI chatbot, and the response by other private firms in the field announced AI's permanent entrance into the public sphere. These recent strides made in the field of artificial intelligence reveal that the pace of technological development has outstripped the rate at which we are able to politically examine and understand these …

Teaching Resilience In Pacific Islander Children Through Culturally Adapted Stories, Isabel Medina Hull

Theses and Dissertations

This study investigated the efficacy of culturally adapted bibliotherapy in promoting resilience among American Samoan children aged 5-13 years in response to high adolescent suicide rates in the Pacific Islands and the need for culturally adapted and supportive interventions grounded in mental health wellness. Bibliotherapy, particularly the identification with story characters, has been recognized for bolstering mental wellness, resilience, and emotional regulation in children. In this research, the children's response to bibliotherapy was measured through card sorting and forced-choice exercises, assessing their engagement with literature mirroring their experiences. The materials were developed in collaboration with Samoan cultural brokers on island …

Vertebral Hu Value And The Pectoral Muscle Index Based On Chest Ct Can Be Used To Opportunistically Screen For Osteoporosis, Xiong-Yi Wang, Sheng Pan, Wei-Feng Liu, Yi-Ke Wang, Si-Min Yun, You-Jia Xu

Faculty, Staff and Student Publications

BACKGROUND: Existing studies have shown that computed tomography (CT) attenuation and skeletal muscle tissue are strongly associated with osteoporosis; however, few studies have examined whether vertebral HU values and the pectoral muscle index (PMI) measured at the level of the 4th thoracic vertebra (T4) are strongly associated with bone mineral density (BMD). In this study, we demonstrate that vertebral HU values and the PMI based on chest CT can be used to opportunistically screen for osteoporosis and reduce fracture risk through prompt treatment.

METHODS: We retrospectively evaluated 1000 patients who underwent chest CT and DXA scans from August 2020-2022. The …

Ecosystem Sentinels As Early-Warning Indicators In The Anthropocene, Elliott L. Hazen, Matthew S. Savoca, T.J. Clark-Wolf, Max Czapanskiy, Peter M. Rabinowitz, Briana Abrahms

Wildland Resources Faculty Publications

We are already experiencing the rapid pace of environmental perturbation in the Anthropocene, necessitating the development of new tools and techniques for measuring changes in ecosystem dynamics. Sentinel species, from birds to invertebrates, have been used to provide insights into ecosystem function, as leading indicators of risk to human health and as harbingers of future change, with implications for ecosystem structure and function. Here, we offer an update to previous research identifying marine top predators as indicators of ecosystem shifts and examine terrestrial sentinels and the latest research on sentinels of pollution and human health. Using ecosystem sentinels enables rapid …

Toward Pedagogies For The Future To Address The Climate Crisis, Edward J. Brantmeier

Journal of Contemplative and Holistic Education

This exploratory article offers contemplative learning exercises that foster connection and intuition in order to promote adaptive intelligence and anticipatory knowing to address the uncertain future related to climate crisis. The author provides personal snapshots and reflections regarding the impact of the climate crisis and explores hopeful paths for everyday action. In specific, the article suggests that everyday revolutionary acts such as slowing down, practicing humility, and aligning economic choices with core values can make a difference. Drawing on a critical pedagogy of place, the author suggests that connection to the ecological places we inhabit matters much in our efforts …

Preparing For The Next Pandemic: Helpful Strategies For Hospital Managers, Lynesha Sweeney

Walden Dissertations and Doctoral Studies

During the rapid spread of the coronavirus in 2020, some hospital managers lacked strategies to support and treat the number of patients falling ill daily. Effective strategies to support and treat patients during the next pandemic are important to hospital managers because insufficient access to quality healthcare services can be harmful to community citizens and detrimental to hospital sustainability. Grounded in the resource-based theory, the purpose of this qualitative pragmatic inquiry was to explore strategies some hospital managers have created and implemented to be prepared for future pandemics within their facilities. The participants were six healthcare leaders working in roles …

Preparing For The Next Pandemic: Helpful Strategies For Hospital Managers, Lynesha Sweeney

Walden Dissertations and Doctoral Studies

During the rapid spread of the coronavirus in 2020, some hospital managers lacked strategies to support and treat the number of patients falling ill daily. Effective strategies to support and treat patients during the next pandemic are important to hospital managers because insufficient access to quality healthcare services can be harmful to community citizens and detrimental to hospital sustainability. Grounded in the resource-based theory, the purpose of this qualitative pragmatic inquiry was to explore strategies some hospital managers have created and implemented to be prepared for future pandemics within their facilities. The participants were six healthcare leaders working in roles …

Defining The Kras- And Erk-Dependent Transcriptome In Kras-Mutant Cancers, Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Alexey Sorokin, Preeti Marie Kanikarla, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John P Shen, Scott Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der

Faculty, Staff and Student Publications

How the KRAS oncogene drives cancer growth remains poorly understood. Therefore, we established a systemwide portrait of KRAS- and ERK-dependent gene transcription in KRAS-mutant cancer to delineate the molecular mechanisms of growth and of inhibitor resistance. Unexpectedly, our KRAS-dependent gene signature diverges significantly from the frequently cited Hallmark KRAS signaling gene signature, is driven predominantly through the ERK mitogen-activated protein kinase (MAPK) cascade, and accurately reflects KRAS- and ERK-regulated gene transcription in KRAS-mutant cancer patients. Integration with our ERK-regulated phospho- and total proteome highlights ERK deregulation of the anaphase promoting complex/cyclosome and other components of the cell cycle machinery as …

Endoscopic Ultrasound-Guided Gastroenterostomy Versus Enteral Stenting For Gastric Outlet Obstruction: Systematic Review And Meta-Analysis, David Forcione

All Publications

Background: The symptoms of gastric outlet obstruction have traditionally been managed surgically or endoscopically. Enteral stenting (ES) is a less invasive endoscopic treatment strategy for this condition. Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) has recently become a potential alternative technique.

Objectives: We conducted a systematic review and meta-analysis of the effectiveness and safety profile of EUS-GE compared with ES.

Design: Meta-analysis and systematic review.

Data sources and methods: We searched multiple databases from inception to August 2023 to identify studies that reported the effectiveness and safety of EUS-GE compared with ES. The outcomes of technical success, clinical success, and adverse events (AEs) …

Cost-Effectiveness And Threshold Analysis Of Deep Brain Stimulation Vs Treatment-As-Usual For Treatment-Resistant Depression, Katherine E Kabotyanski, Ricardo A Najera, Garrett P Banks, Himanshu Sharma, Nicole R Provenza, Benjamin Y Hayden, Sanjay J Mathew, Sameer A Sheth

Faculty, Staff and Students Publications

Treatment-resistant depression (TRD) affects approximately 2.8 million people in the U.S. with estimated annual healthcare costs of $43.8 billion. Deep brain stimulation (DBS) is currently an investigational intervention for TRD. We used a decision-analytic model to compare cost-effectiveness of DBS to treatment-as-usual (TAU) for TRD. Because this therapy is not FDA approved or in common use, our goal was to establish an effectiveness threshold that trials would need to demonstrate for this therapy to be cost-effective. Remission and complication rates were determined from review of relevant studies. We used published utility scores to reflect quality of life after treatment. Medicare …

Arthropod Associates Of The Gray Catbird On Vaca Key, Lawrence J. Hribar, Aline D. Tassi

Florida Field Naturalist

No abstract provided.

Interactions Between Sympatric Florida Scrub-Jays And Southeastern American Kestrels, Karl E. Miller, Benjamin Ewing

Florida Field Naturalist

No abstract provided.

Winter Return Rates, Patch Fidelity, And Response To Prescribed Fire For Grasshopper And Savannah Sparrows In Southwestern Florida, Bob Altman, Kathleen N. Smith, Joseph Bozzo, Robert T. Meyer

Florida Field Naturalist

No abstract provided.

Black Spiny-Tailed Iguana (Ctenosaura Similis) Use Of Gopher Tortoise (Gopherus Polyphemus) Burrows In Buckingham, Florida, Josie Rivero, Andrew M. Durso

Florida Field Naturalist

No abstract provided.

Patterns Of Scavenging On Bird Carcasses In A Coastal Subtropical Environment, David W. Kerstetter, Garrett A. Hardy, Laura John

Florida Field Naturalist

No abstract provided.

Current Distribution Of Black Rails In Florida, Amy C. Schwarzer, Gina Kent, Bryan D. Watts, Ken Meyer, Amanda Powell, Brittany Bankovich, W. Andrew Cox

Florida Field Naturalist

No abstract provided.

Comparing The Frequency Of Incest Between Siblings In Two Populations Of Florida Scrub-Jays (Aphelocoma Coerulescens), Kelly A. Roberts, Abigail Valine, Angela Tringali, Michelle Dent, Reed Bowman

Florida Field Naturalist

No abstract provided.

Sherman's Bummers And The Depths Of Modern War, Nate Wilkins

Chronos

No abstract provided.

Noda News January 2018

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

Population Estimate For The American Kestrel In The Great Valley Section Of Pennsylvania, G. Robert Ganis

Eastern Bird Banding Association News

No abstract provided.