Digital Commons Network^™

Impact Of Essential Genes On The Success Of Genome Editing Experiments Generating 3313 New Genetically Engineered Mouse Lines., Hillary Elrick, Kevin A Peterson, Brandon J Willis, Denise G Lanza, Elif F Acar, Edward J Ryder, Lydia Teboul, Petr Kasparek, Marie-Christine Birling, David J Adams, Allan Bradley, Robert E Braun, Steve D Brown, Adam Caulder, Gemma F Codner, Francesco J Demayo, Mary E Dickinson, Brendan Doe, Graham Duddy, Marina Gertsenstein, Leslie O Goodwin, Yann Hérault, Lauri G Lintott, K C Kent Lloyd, Isabel Lorenzo, Matthew Mackenzie, Ann-Marie Mallon, Colin Mckerlie, Helen Parkinson, Ramiro Ramirez-Solis, John R Seavitt, Radislav Sedlacek, William C Skarnes, Damien Smedley, Sara Wells, Jacqueline K White, Joshua A Wood, International Mouse Phenotyping Consortium, Stephen A Murray, Jason D Heaney, Lauryl M J Nutter

Faculty Research 2024

The International Mouse Phenotyping Consortium (IMPC) systematically produces and phenotypes mouse lines with presumptive null mutations to provide insight into gene function. The IMPC now uses the programmable RNA-guided nuclease Cas9 for its increased capacity and flexibility to efficiently generate null alleles in the C57BL/6N strain. In addition to being a valuable novel and accessible research resource, the production of 3313 knockout mouse lines using comparable protocols provides a rich dataset to analyze experimental and biological variables affecting in vivo gene engineering with Cas9. Mouse line production has two critical steps - generation of founders with the desired allele and …

State Of Illinois Model Programs Of Study Guides: 2024 Utilization Report, Meagan Mitchell

Reports, Analyses, and other Publications

No abstract provided.

Operating Fund Budget/ Expenditure Detail Report 2024-25, Csusb Budget Office

University Budget Office records

No abstract provided.

Facta Health Inc V. Pharmadent Llc

2024 Decisions

USDC for the District of New Jersey

Mississippi State University Libraries Branches – Collection Development Policy, Mississippi State University Libraries

Policies and Procedures

No abstract provided.

Digital Education On Hospital Nutrition Diets: What Do Patients Want To Know?, Neha Gutta, Som Singh, Dharti Patel, Aleena Jamal, Fawad Qureshi

SKMC Student Presentations and Publications

INTRODUCTION: Therapeutic nutrition plays an imperative role during a patient's hospital course. There is a tremendous body of literature that emphasizes the systematic delivery of information regarding hospital nutrition diets. A major component of delivering healthcare information is the principle of providing quality healthcare information, but this has not yet been investigated on hospital nutrition diets. This study aimed to evaluate the comprehension and readability of patient education materials regarding therapeutic hospital diets.

METHODOLOGY: The methodology employed the use of publicly available questions regarding hospital nutrition diets and categorized them per Rothwell's Classification of Questions. Additionally, the questions were extracted …

Conversion Of Fish Waste Oil Into Biofuel: An Experimental Study, Mahmoud A. Mohamed, Hany A. Elazab, Mamdouh A. Gadalla, Fatma A. Ashour

Chemical and Biochemical Engineering Faculty Research & Creative Works

Egypt is famous for its fish wealth, given its large coasts and freshwater resources, especially of Nile Tilapia and Mugilid fish. It was estimated that domestic fish production increased from 889 thousand tonnes in 2005 to 1620 thousand tonnes in 2016. Thousands of tonnes of fish are consumed yearly, generating substantial amounts of fish waste and residues. Some 26% of the fish consumed is a typical waste. Fish wastes have a significant role in many processes and applications. They are used as feedstock for producing fish meals, a major by-product of fish waste oil. Fish oil is extracted for medical …

The Effect Of Verbal Harassment On The Psychological Factor Among Female Students Of The Sports Sciences College At The University Of Jordan, Anas Mohammed Khair

Modern Sport

The study aimed to identify the impact of verbal harassment on the psychological state of female students at Sports Sciences College at the University of Jordan. The researcher used a descriptive approach suitable for the nature of this study. The study population consisted of female undergraduate and postgraduate students at Sports Science College at the University of Jordan, totaling 754 students. A random sample of 92 students was selected, and a questionnaire prepared by the researcher was distributed among them. To process the questionnaire data, the researcher used the Statistical Package for the Social Sciences (SPSS) to obtain arithmetic means, …

Manufacturing An Innovative Device To Adjust The Distance Between Female Fencing Players' Feet, Rimah Muhammad Zuwayr, Fatimah Abed Malih, Jeki Haryanto

Modern Sport

In this research, the role of artificial intelligence and modern technology in the training process was discussed in a way that serves its goals and benefits from it through good outcomes, as employing technology in fencing training facilitates the training process for the coach and player and contributes to reducing the effort expended and the time spent. The study aimed to identify on the effect of the manufactured device in controlling the distance between the feet in the research sample, the experimental method was used by designing the experimental and control groups. The research sample consisted of female fencing team …

High Fat, High Sucrose Diet Promotes Increased Expression Of Ace2 Receptor In The Siv-Infected Host: Implications For Sars-Cov-2 Infection, Elizabeth C. Delery, Danielle E. Levitt, Angela M. Amedee, Patricia E. Molina, Liz Simon

School of Graduate Studies Faculty Publications

Introduction: People with pre-existing conditions, including metabolic comorbidities, are at greater risk for complications of SARS-CoV-2 infection and expression of machinery required for viral entry into host cells may be a contributing factor. This study tested the hypothesis that high fat, high sucrose diet (HFSD) and alcohol use increase expression of angiotensin converting enzyme 2 (ACE2) receptor and transmembrane serine protease 2 (TMPRSS2) in tissues isolated from simian immunodeficiency virus (SIV) infected macaques, the most clinically relevant model for the study of HIV. Methods: Biospecimens obtained from a longitudinal study of SIV-infected, antiretroviral therapy (ART)-treated female rhesus macaques (Macaca mulatta) …

Robust And Generalizable Representations In The Hippocampus, Hung-Tu Chen

Dartmouth College Ph.D Dissertations

An intelligent system must balance generalizing across similar experiences with maintaining the distinctiveness of each experience. This thesis explores how the hippocampus manages this balance through its neural representations to support adaptive behavior. In Chapter 1, I provide an overview of key hippocampal phenomena that contribute to this process, including remapping, splitter signal, and replay. In Chapter 2, I challenge the concept of random remapping by showing that it is possible to predict, better than chance, how a given experience will be encoded in the hippocampus across different subjects. This suggests that encoding of related experiences, which was previously thought …

Unconditional Cash Transfer Policy As An Effort To Prevent Stunting: A Study On Jember, East Java, Allen Pranata Putra, Sri Juni Woro Astuti, Kabiru Hannafi Ibrahim

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

This study evaluates the impact of the Unconditional Cash Transfer (UCT) policy in preventing stunting in Jember, East Java. Stunting, a result of chronic malnutrition, remains a significant public health challenge in Indonesia, with Jember exhibiting higher prevalence rates than the national average. The UCT policy aims to improve the welfare of low-income families by providing direct financial assistance, allowing them to meet basic needs, including nutrition. This research utilizes a qualitative approach through case studies and interviews with relevant stakeholders to assess the effectiveness of UCT in enhancing children's nutrition and health. The findings indicate that while UCT has …

Development Of E-Modules Based On Pjbl-Steam And Virtual Simulation Media On Work And Energy Topic As An Effort To Improve Students’ Critical Thinking Skills, Farah Rafidah, Parno Parno, Nasikhudin Nasikhudin, Marlina Ali

Jurnal Pendidikan Sains

Work and energy are fundamental topics in physics. However, enhancing students’ critical thinking skills in these areas remains a challenge. This research aimed to develop and assess the validity and readability of e-modules designed with PjBL-STEAM and virtual simulation media to address this issue. The development process followed a 4D model, and the resulting e-modules were evaluated as strongly valid category. The validation tests yielded percentage scores of 91.6% for media, 89.3% for content, and 88.0% for lesson plans. Additionally, the readability test achieved a score of 84.6%, indicating a excellent level of comprehensibility. These findings suggest that the e-modules …

Comparative Analysis In The Effectiveness Of Real Vs. Virtual Labs In Enhancing Students’ Conceptual Understanding Of Archimedes’ Principle, Judeanto Edy, Sutopo Sutopo, Edi Supriana

Jurnal Pendidikan Sains

This research aimed to investigate the effectiveness of virtual laboratories compared to real laboratories in improving students’ conceptual understanding of Archimedes’ principle. A quantitative approach was employed using a pretest-posttest design. The measurement instrument used in this study was a concept mastery test, consisting of 15 multiple-choice questions. Data were analyzed using an independent sample T-test. The research involved students from two XI IPA classes, each consisting of 33 students. The findings indicated that both virtual and real laboratories in the learning process could enhance students’ conceptual understanding. The study concluded that there was no significant difference between the virtual …

Impact Of Bypass Fat Supplementation On Milk Production And Weight Gain In Nili Ravi Buffaloes Under Southern Khyber Pakhtunkhwa's Geo-Climatic Conditions, Shahzeb Khan, Arsalan Khan, Asad Ullah, Abid Ullah, Amjad Ali, Safi Ullah, Imran Khan, Muhammad Yasir, Israr Ud Din, Atta Ur Rehman, Muhammad Rizwan, Jahangir Ali

Journal of Bioresource Management

This study was conducted to examine the effect of bypass fat supplementation on milk production, composition, and body weight gain in Nili Ravi Buffaloes living in the unique geo-climatic conditions of Southern Khyber Pakhtunkhwa. Twenty lactating Nili Ravi buffaloes were randomly assigned to control and bypass fat supplementation groups in randomized, controlled experiment. Over the course of three months, data were collected on milk yield, milk composition, and body weight while environmental factors were considered. The bypass fat group gained significantly more weight on average than the control (p0.05). Bypass fat supplementation can substantially increase milk production, milk fat content, …

Estimation Of Bovine Tuberculosis Prevalence, Associated Risk Factors, And Public Health Significance In District Dera Ismail Khan, Arsalan Khan, Akhtar Ali, Umm E. Aimen, Wasim Ullah, Imtiaz Khan, Qamar Ullah, Baqir Hussain, Muneeb Ur Rahman

Journal of Bioresource Management

Bovine tuberculosis (bTB) is zoonotic disease of global concern, affecting both animal and human populations. To estimate the prevalence of bovine TB in District Dera Ismail Khan and identify associated risk factors. A total of 138 cattle from different herds were included in the survey, and diagnostic tests, including the tuberculin skin test and Ziehl Neelsen stain, were employed. The results revealed a high prevalence of bovine TB, with an estimated prevalence of 10.87 % in the study area. Prevalence analysis based on tehsils revealed varying rates: 6.66 % in Dera Ismail Khan, 11.11 % in Kulachi, and 14.81 % …

A Review On Potential For Organic Farming In Pakistan, Amir Raza, Shahzada Asif Ali, Haroon Shahzad

Journal of Bioresource Management

Intensive use of agrochemicals (fertilizers and pesticides) has enhanced crop productivity in Pakistan. This rise in productivity has been achieved at the cost of degradation of natural resources (land and water), and environmental pollution. The current situation demands a gradual transformation towards eco-friendly farming practices like organic farming to ensure the sustainability of the agriculture sector. This article presents our viewpoint on the potential benefits of organic farming, its role in mitigating the impact of climate change and the potential for adoption and promotion of organic farming in Pakistan. Organic farming seems to offer promising opportunities on account of its …

Downregulation Of Piezo2 In The Detrusor Of Men With Bladder Outlet Obstruction And Its Association With Urinary Retention And Decreased Bladder Compliance, Carlos Henrique Suzuki Bellucci, Thiago Souto Hemerly, Luisa Resende Tenório De Albuquerque, Ruan Pimenta, Vanessa Guimaraes Schreiter, Sabrina Thalita Dos Reis, Jose De Bessa Jr, Katia Ramos Moreira Leite, Alberto Antunes, Boopathi Ettickan, William C. Nahas, Cristiano Mendes Gomes

Center for Translational Medicine Faculty Papers

PURPOSE: Recent research has highlighted the mechanotransducer PIEZO2 as a crucial factor in lower urinary tract function, demonstrating associations with bladder compliance (BC), bladder wall thickening, and elevated bladder pressure. We explored the hypothesis that PIEZO2 expression may be associated with lower urinary tract dysfunction in men with bladder outlet obstruction (BOO) due to benign prostatic hyperplasia (BPH).

METHODS: The study included a consecutive series of patients undergoing open prostatectomy for BPH at our hospital between September 2014 and January 2016. All participants underwent comprehensive preoperative evaluations, including urodynamic assessments. During prostatectomy, a full-thickness fragment of the bladder wall was …

A Comprehensive Study On One Health Strategy And Public Health Effects Of Salmonella, Muhammad Aqeel, Amjad Hussain Mirani, Parvez Ahmed Khoso, Jam Kashif Sahito, Riaz Ahmed Leghari, Abdul Latif Bhutto, Muhammad Mohsen Rahimoon, Abdul Azeem Khoso, Rasool Bux, Azmat Aliasn Arsalan Ali

Journal of Bioresource Management

Salmonella poses a significant public health challenge due to its antibiotic resistance, zoonotic transmission, and diverse clinical manifestations. Over 60 % of human diseases are zoonotic, influenced by ecological dynamics and human activities such as land use changes, population growth, and international travel. Foodborne diseases, particularly those caused by Salmonella spp., have a substantial global impact, especially in low-income countries. Salmonella is divided into two species, Salmonella enterica and Salmonella bongori, with more than 2000 serotypes and six subspecies within S. enterica. This bacterium is highly adaptable, surviving extreme conditions such as drying, high salt concentrations, and acidic …

Contextualizing The Sdgs In The Anthropocene: Case Study Of Mekong Women’S Adaptation To Hydropower Dams In Northern Thailand, Maya Dania

Asia-Pacific Social Science Review

Large dams are among the most massive infrastructures built in the Mekong River and provide water-energy generators in the Lower Mekong Basin (LMB). Nevertheless, the Mekong River’s current transformation using electricity utilizing hydropower technology has damaged the local ecosystem in the LMB with social and environmental effects. Drawing upon feminist posthumanism, this study argues that the ongoing hydropower dam constructions in the LMB reflect uneven development and exclusion for women and the more-than-human nature of Mekong biodiversity. With a case study of Mekong women’s adaptation to regional development projects, this study aims to contextualize SDGs in the global crisis of …

Evaluation Of Therapeutic Efficacy Of Aloe Rabaiensis Leaf Against Salmonella Gallinarum Challenged In Kuroiler Chicks In Arusha, Tanzania, Mwanaisha S. Mkangara

Tanzania Journal of Science

Salmonella gallinarum, a bacterium causing fowl typhoid in gallinaceous birds, poses significant economic challenges to the chicken industry in Tanzania. This study investigated the potential of Aloe rabaiensis in managing S. gallinarum in Kuroiler chicks. The clinical signs, viable cell count, live weight, heterophils, lymphocytes, and monocyte counts were evaluated using ninety-four chicks grouped into T1, T2, T3 (challenged with S. gallinarum), and T4 (unchallenged with S. gallinarum). The findings revealed no statistically significant differences between the treated and control groups (P > 0.05) in viable cell count, live weight, mortality rate, heterophils, lymphocytes, and monocyte counts. However, there were clinical …

Effect Of Citrus Sinensis And Musa Textilia Consumption On Lactic Acid Levels And Muscle Tension In Fish Auction Workers, Bina Kurniawan, Mohammad Zen Rahfiludin, Yuliani Setyaningsih, Nurjazuli Nurjazuli

Media Kesehatan Masyarakat Indonesia

Potassium deficiency is known to induce muscle fatigue, necessitating the inclusion of potassium-rich foods, such as orange (Citrus sinensis) and banana (Musa textilia) in diet. Previous studies have shown that consuming 150 g and 300 g of banana is effective in preventing muscle fatigue, with orange containing 237.4 mg of potassium per 300 ml. Therefore, this study aims to examine the relationship between lactic acid concentration and muscle tension reduction in fish auction workers after the administration of orange and banana. The study procedures were carried out with a quasi-experimental pre-test and post-test group design, and …

Nitric Oxide Levels In Primary Hypertension Patients Receiving Wet Cupping Therapy, Nurhayani Nurhayani, Dwi Pudjanarko, Nurahmi Nurahmi, Misriyani Misriyani

Media Kesehatan Masyarakat Indonesia

Wet cupping has been shown in several studies to lower blood pressure in hypertensive patients. However, the mechanism of action remains unknown, limiting its use as a complementary non-pharmacological treatment. This study aims to examine the effect of wet cupping on systolic blood pressure, diastolic blood pressure, and nitric oxide levels in hypertensive patients. The study employed a quasi-experimental method with a pretest and post-test design, including a control group. The sample consisted of 40 individuals, they were diagnosed with primary grade I hypertension. The participants were divided into two groups (treatment and control). The intervention group received wet cupping …

Foodborne Outbreak Investigation In Elementary School Students In Bantul, Yogyakarta, 2023, Soraya Isfandiary Iskandar, Miftakhul Janah, Samsu Aryanto, Bayu Satria Wiratama

Media Kesehatan Masyarakat Indonesia

Bantul District Health Office received notification that 75 students in elementary school were sick with symptoms of nausea, vomiting, and dizziness after they consumed snacks from the school canteen. An epidemiological investigation was conducted to confirm the outbreak, identify additional cases, determine risk factors and causes, and recommend preventive measures. This investigation conducted active case finding followed by a retrospective cohort study. Individuals who experience one or more symptoms, such as nausea, vomiting, diarrhea, stomach pain, dizziness, fever, and malaise after consuming snacks were defined as cases. Data was collected through direct interviews with students, teachers, staff, and food sellers. …

Intouch Week Of September 30, 2024, New York Medical College

InTouch

• NYMC Celebrates Visionary Public Health Leaders at Annual Founder’s Dinner
• NYMC.edu Gets a Makeover
• TCDM Expands to New Mexico
• NYMC Places Fourth in the 2024 American Heart Association Westchester Heart Walk
• Together in Wellness: An Immersive Experience for Mind, Body, and Community
• Chavi Eve Karkowsky, M.D., Shares Powerful Stories and Insights on High-Risk Pregnancy During Community Book Discussion
• Students, Staff, and Faculty Find Relief at Pet the Stress Away Event
• 10 Things You Can Do for Your Mental Health
• Study Highlights Racial Inequities in Foster Care Placement Following Non-Accidental Trauma

Production And Purification Of Biodiesel: A Short Review, Achol Aguek Tengteng, Muhammad Faseeh Memon, Wan Nur Aisyah Wan Osman, Shafirah Samsuri

Platform: A Journal of Engineering (PAJE)

The exploration of renewable energy alternatives is imperative due to the increasing environmental consequences of fossil fuel energy consumption. The production of Biodiesel from sustainable sources, such as non-edible oil waste and refuse cooking oil, arises as a compelling solution to mitigate environmental degradation. This comprehensive review explores the synthesis and purification processes essential to biodiesel production, emphasising the utilisation of various manufacturing techniques, particularly transesterification, which employs a variety of catalysts and feedstocks. Diverse biodiesel sources are examined, highlighting the environmental benefits and performance metrics. The purification methods employed to improve the quality and efficacy of Biodiesel are also …

Maximizing Growth And Yield Of Black Seed (Nigella Sativa L) Through Optimized Phosphorus And Boron Levels, Abdul Qudoos Khan, Abdul Qadeer Khan, Hanif Ullah, Navid Iqbal, Muhammad Junaid, Imad Murad, Faridullah Mamozai, Romaisa Amin, Waleed Iqbal, Uzair Ahmed

Journal of Bioresource Management

Improper nutrient management cause yield reduction in black seed yield and quality. Therefore, a field trial was executed in the growing season 2022-23 at The University of Agriculture Peshawar to inspect the effects of different phosphorus (P) and boron (B) levels on black seed (Nigella sativa L.). The experiment used a randomized complete block design with a split-plot arrangement, replicated thrice. The study examined four P levels (0, 15, 30, and 45 kg/ha) and four B levels (0, 1, 2, and 3 mg/L) on various growth and yield parameters of black seed. Plots treated with 45 kg/ha of P …

Trace Out The Improvement Level And Awareness Of Polycyctic Ovary Syndrome (Pcos) Among General People And Educational Institute Of Developed And Developing Countries, Muhammad Rizwan, Maryam Mushtaq, Asif Bilal, Tabassum Nawaz, Kashif Riaz, Maria Hussain, Mirza Fahad Baig, Saira Ashfaq, Ayesha Mushtaq, Umair Riaz, Mariya Basharat

Journal of Bioresource Management

One of the most prevalent hormonal problems which affect women is polycystic ovary syndrome (PCOS). It consists of several fundamentals, including reproductive, metabolic, and cardiovascular ones, and has effects on the patient's health throughout the duration of their life. Limited data is available on PCOS in developing countries like Pakistan. The aim of our study is to trace out the prevalence of PCOS in developed countries like America and China as well as developing countries like Pakistan. The study was done in the above mention developed and developing countries through the interviews of people by online questionnaire. This survey research …

Evaluation Of Cotton Advanced Lines/Varieties For Genetic Diversity And Correlation Studies Of Cotton Leaf Curl Virus Disease With Yield Contributing Traits In Cotton, Nouman Bilal, Wajid Nazeer, Abdul Latif Tipu, Shoaib Liaqat, Muhammad Sarwar, Ansar Ali, Khadim Hussain, Maria Basheer

Journal of Bioresource Management

Plant genetic diversity aids in the creation of new varieties that are more resistant to pests and unfavorable climatic conditions. In order to discover varied parents and assess their cross-performance, the current study was carried out. The findings showed a substantial positive connection (0.81) between green bolls, plant height (0.57), and open bolls, as well as a significant positive correlation (0.52) between open bolls. On the other hand, a highly significant negative connection was discovered between the number of open bolls (-0.59), number of green bolls (-0.72), plant height (-0.78), and major stem nodes (-0.70) for the cotton leaf curl …

Brucellosis And Its Diagnostic Techniques In Animals: A Comprehensive Review, Muhammad Mohsen Rahimoon, Amjad Hussain Mirani, Jam Kashif Sahito, Abdul Latif Bhutto, Pervez Ahmed Khoso, Riaz Ahmed Laghari, Asmatullah Kaka, Muhammad Aqeel, Ghulam Rasool Rahimmon

Journal of Bioresource Management

Brucellosis is a highly zoonotic infection found in animals and human, it has a high death ratio and lifetime sterility rate. The rates of intra- and interspecific infections have dramatically increased in recent years as a result of inadequate management and scarce resources particularly in developing nations. In cattle, reduced milk yield and elevated body temperature are the primary indicators, whereas in humans, soaring fever, overall malaise, and arthritis are the hallmarks of late-term abortion. Despite the fact that this diseases in animals and humans found unclear clinically, it will leads towards the hindrance in diagnosing this infectious illness serologically, …