Digital Commons Network^™

Joint Senate Meeting Minutes 11-19-24, Unk Student Government

Joint Senate Meeting Minutes

No abstract provided.

Compositions And Methods Relating To Novel Sulfono-Gamma-Aa Peptides, Chuanhai Cao, Jianfeng Cai

USF Patents

Provided herein are compounds, compositions, pharmaceutical compositions, kits, and methods relating to novel sulfono-γ-AA peptides. Novel sulfono-γ-AA peptides as described herein can have the structure according to Formula 1: In embodiments according to the present disclosure, novel sulfono-γ-AA peptides as described herein have minimal toxicity, can repair neuronal damage, inhibit Amyloid beta aggregation, and promote cellular growth and viability.

Systems And Methods For Classifying Mosquitoes Based On Extracted Masks Of Anatomical Components From Images, Sriram Chellappan, Mona Minakshi, Pratool Bharti, Ryan M Carney

USF Patents

Images of an insect are subjected to at least a first convolutional neural network to develop feature maps based on anatomical pixels at corresponding image locations in the respective feature maps. The anatomical pixels correspond to a body part of the insect. A computer calculates an outer product of the first feature map and the second feature map to form an integrated feature map. Extracting fully connected layers from respective sets of integrated feature maps and applying the fully connected layers to a classification network for identifying the genus and the species of the insect.

Methods For Sampling Into An Atmospheric Pressure Inlet Mass Spectrometer, Theresa Evans-Nguyen, Linxia Song, Yi You

USF Patents

Provided herein are systems and methods for sampling analytes into an atmospheric pressure inlet mass spectrometer using ultrasonic nebulization-assisted atmospheric pressure chemical ionization. The systems can include a mass spectrometer having an input and an ultrasonic nebulizer chip. The ultrasonic nebulizer chip can be operatively coupled to the mass spectrometer, such that when the ultrasonic nebulizer chip nebulizes the analyte to provide a nebulized analyte, at least some of the nebulized analyte enters the input of the mass spectrometer.

Plasma Derived From Human Umbilical Cord Blood For The Treatment Of Neurodegenerative Disorders, Svitlana Garbuzova-Davis, Jared Carl Ehrhart, Paul R. Sanberg

USF Patents

A method of treating neurodegenerative diseases using hUCB plasma is presented herein. hUCB plasma attenuated the hyperactive response (Group III) and potentiated the normal response in Group I ALS patients, but did not alter that of the non-responders to PHA (Group II). The elevated activity of caspase 3/7 observed in the MNCs from ALS patients was significantly reduced by hUCB plasma treatment. The ability of hUCB plasma to modulate the mitogen cell response and reduce caspase activity suggest that the use of hUCB plasma alone, or with stem cells, may prove useful as a therapeutic in ALS patients. hUCB plasma …

Il-37 Suppresses Cns Autoimmunity By Increasing The Frequency Of Treg Cells And Reducing Cd4 + T Cell-Derived Il-10 Production, Reza Yazdani, Hamed Naziri, Gholamreza Azizi, Bogoljub Ciric, Mozhde Askari, Amir Moghadam-Ahmadi, Jaya Aseervatham, Guang-Xian Zhang, Mohamad Rostami

Department of Neurology Faculty Papers

BACKGROUND: Interleukin-37 (IL-37) has anti-inflammatory properties in innate and adaptive immunity. Patients with multiple sclerosis (MS), an autoimmune inflammatory demyelinating disease of the central nervous system (CNS), have increased serum levels of IL-37. However, it is unknown whether IL-37 has an inhibitory effect on ongoing autoimmune neuroinflammation, thus offering a potential MS therapy.

AIM: Here, we examined the effect of IL-37 in an experimental autoimmune encephalomyelitis (EAE) model after disease onset to determine if it was protective.

FINDINGS: IL-37-treated mice developed a less severe disease than control mice, with reduced demyelination as determined by increased expression of myelin basic protein. …

Cas Connections- 2024 Fall Term - November, Dean's Office College Of Arts And Science

CAS Connections

No abstract provided.

Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude

Faculty Publications

Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …

Disordered Proteins Interact With The Chemical Environment To Tune Their Protective Function During Drying, Shraddha Kc, Kenny H Nguyen, Vincent Nicholson, Annie Walgren, Tony Trent, Edith Gollub, Paulette Sofia Romero-Perez, Alex S Holehouse, Shahar Sukenik, Thomas C Boothby

2020-Current year OA Pubs

The conformational ensemble and function of intrinsically disordered proteins (IDPs) are sensitive to their solution environment. The inherent malleability of disordered proteins, combined with the exposure of their residues, accounts for this sensitivity. One context in which IDPs play important roles that are concomitant with massive changes to the intracellular environment is during desiccation (extreme drying). The ability of organisms to survive desiccation has long been linked to the accumulation of high levels of cosolutes such as trehalose or sucrose as well as the enrichment of IDPs, such as late embryogenesis abundant (LEA) proteins or cytoplasmic abundant heat-soluble (CAHS) proteins. …

Human Studies Of The Efficacy And Safety Of Stem Cells In The Treatment Of Diabetic Peripheral Neuropathy: A Systematic Review And Meta-Analysis, Seyed Danial Alizadeh, Shima Jahani, Mohammad Rezaei Zadeh Rukerd, Reza Tabrizi, Rasoul Masoomi, Seyedeh Zahra Banihashemian, Mahgol Sadat Hassan Zadeh Tabatabaei, Zahra Ghodsi, Ahmad Pour-Rashidi, James Harrop, Vafa Rahimi-Movaghar

Department of Neurosurgery Faculty Papers

OBJECTIVE: To assess the efficacy and safety of stem cell therapy in human studies for diabetic peripheral neuropathy (DPN).

METHODS: A comprehensive literature review was performed across multiple databases, including Ovid MEDLINE ALL, Embase via Ovid SP, Scopus, Web of Science Core Collection, and Cochrane CENTRAL, up to January 31, 2024. Keywords and controlled vocabularies related to diabetic neuropathy and stem cell therapy were used. Inclusion criteria encompassed all controlled trials examining stem cell therapy for DPN, excluding animal or in vitro studies, review papers, conference abstracts, and editor letters. Data extraction and risk of bias assessment were independently performed …

A Systematic Exploration Of Theoretical, Conceptual, And Methodological Alignment Of Social Network Analysis In Organizational Behavior, Morgan Gleason Miller

College of Science and Health Theses and Dissertations

This systematic review examines how Social Network Analysis (SNA) is used in the study of Organizational Behavior (OB). Industrial-Organizational Psychology Literature suggests SNA tends to be applied using either a structural or relational approach (Erikson, 2013). Some researchers claim that this methodology is applied inconsistently due to the intermingling of two distinct underlying frameworks and the exclusion of individual differences and interpersonal factors limits the relevance of SNA (Erikson, 2013; Kilduff & Lee, 2020). Results indicate the structural perspective is slightly dominant across the use of SNA, but the use of both frameworks is increasing. Directionally, study methods aligned with …

The George-Anne, Georgia Southern University

The George-Anne

• Donald Trump Wins 2024 Presidential Race
• Last Ride in Hanner ends in Victory
• Hidden Gems: The Flowergirl
• Nothing but the Truth
• How True Crime show "The Erik and Lyle Menendez Story" may affect their resentencing
• GS Current Athletic Director Accepts New Position at Auburn, New Athletic Director Announced
• Armstrong students react to Trump's return to office
• Armstrong's Fang-tastic Halloween Costumes
• Best of Armstrong Fashion
• Armstrong Knows How to Celebrate
• The Artsy Girl

Are Biobased Microfibers Less Harmful Than Conventional Plastic Microfibers: Evidence From Earthworms, W. Courtene-Jones, F. De Falco, F. Burgevin, R. D. Handy, R. C. Thompson

School of Geography, Earth and Environmental Sciences

Biobased plastics are sometimes promoted as “environmentally friendly” compared to their conventional petrochemical-based counterparts, but their ecotoxicity is only partially understood. Biobased fibers are widely used in clothing and wet wipes and can accumulate in soils through the application of biosolid fertilizers. This study examined the lethal thresholds and sublethal toxicity of chemically characterized, additive-free, biobased (viscose and lyocell) compared to petrochemical-based (polyester) fibers on the key ecosystem engineer, Esenia fetida. Viscose and lyocell had LC₂₀ values of 14.00 and 22.66 mg·L^-1, respectively, and no observed effect concentrations (NOEC) of 0-2.8 mg·L^-1 (72 h, OECD TG207 …

A Retrospective Analysis Of Mortality Due To Pneumonia And Renal Disease In A Midwestern Patient Population, Robert Hillard, Joselyn Schmitz, Benjamin Kossman, Lane Mittler, Vishnu Basude, Nova Beyersdorfer, Kerry Johnson, John Paulson

Student Publications

Background: The impact of pneumonia (PNA) with concomitant renal disease (RD) has not been fully investigated in a United States Midwestern patient population, despite the morbidity and mortality associated with such diseases.

Materials and methods: A retrospective cohort study was performed on International Classification of Diseases, 10th Revision (ICD-10) data from a hospital system located in Southwest Missouri. Data was acquired from patients admitted between January 2019 and December 2021. Patients were separated into five groups (disease categories): acute kidney injury (AKI), chronic kidney disease (CKD), PNA, AKI with PNA, and CKD with PNA. The data were analyzed, and subset …

Body Condition Scoring For Sheep, Abigail Johnson, Reganne K. Briggs, Chad Page

All Current Publications

Body condition scoring is a helpful tool for sheep producers to use to evaluate the status of their flock. This fact sheet illustrates how to condition score sheep and the importance of condition scoring on production.

Samd7 Represses Short-Wavelength Cone Genes To Preserve Long-Wavelength Cone And Rod Photoreceptor Identity, Leo I Volkov, Yohey Ogawa, Ramiz Somjee, Hannah E Vedder, Hannah E Powell, Deepak Poria, Sam Meiselman, Vladimir J Kefalov, Joseph C Corbo

2020-Current year OA Pubs

The role of transcription factors in photoreceptor gene regulation is fairly well understood, but knowledge of the cell-type-specific function of transcriptional cofactors remains incomplete. Here, we show that the transcriptional corepressor

Discovery Of Highly Potent And Alk2/Alk1 Selective Kinase Inhibitors Using Dna-Encoded Chemistry Technology, Ravikumar Jimmidi, Diana Monsivais, Hai Minh Ta, Kiran L Sharma, Kurt M Bohren, Srinivas Chamakuri, Zian Liao, Feng Li, John M Hakenjos, Jian-Yuan Li, Yuji Mishina, Haichun Pan, Xuan Qin, Matthew B Robers, Banumathi Sankaran, Zhi Tan, Suni Tang, Yasmin M Vasquez, Jennifer Wilkinson, Damian W Young, Stephen S Palmer, Kevin R Mackenzie, Choel Kim, Martin M Matzuk

Faculty, Staff and Students Publications

Activin receptor type 1 (ACVR1; ALK2) and activin receptor like type 1 (ACVRL1; ALK1) are transforming growth factor beta family receptors that integrate extracellular signals of bone morphogenic proteins (BMPs) and activins into Mothers Against Decapentaplegic homolog 1/5 (SMAD1/SMAD5) signaling complexes. Several activating mutations in ALK2 are implicated in fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine gliomas, and ependymomas. The ALK2 R206H mutation is also present in a subset of endometrial tumors, melanomas, non–small lung cancers, and colorectal cancers, and ALK2 expression is elevated in pancreatic cancer. Using DNA-encoded chemistry technology, we screened 3.94 billion unique compounds from our diverse …

Factors Affecting Colostrum Yield: Mastitis, Calf Size, And Udder Size, Peter S. Erickson

UNH Cooperative Extension

No abstract provided.

Can The Effluent From Wastewater Stabilization Ponds Be Effectively Managed For Health And Nutrient Recovery?, Michael Glass

USF Tampa Graduate Theses and Dissertations

Wastewater stabilization ponds, such as facultative and maturation lagoons, have been shown to be effective processes to manage conventional water quality parameters found in domestic wastewater. The main goal of this thesis is to explore whether wastewater stabilization ponds can simultaneously reduce pathogens to safe levels while supporting agricultural activities through nutrient recovery. A large dataset for water quality of wastewater lagoon effluent in the U.S. was obtained at the state level and combined into regional southern and northern locations. Analysis of data showed there was significant difference in lagoon effluent concentration between northern and southern states for the water …

Research Tools For Graduate Students: Reflections On Eight Years Of Graduate Student Workshops, Lisa Becksford Russell

Journal of Graduate Librarianship

This article will describe the author’s graduate student outreach efforts over the last eight years, including graduate student orientations, open houses, and workshops. The development of a long-running graduate student workshop series is described in detail, and the author shares lessons learned from her outreach experiences.

Archeologically Speaking For Texas, Marvin Glasgow, Nolan E. Preston

North Texas Archeological Society Records

A archeological dictionary with common words in Texas archeology, dated for 2001.

Archeologically Speaking For Texas, Marvin Glasgow, Nolan E. Preston

North Texas Archeological Society Records

A archeological dictionary with common words in Texas archeology, dated for 1993.

Archeologically Speaking For Texas, Marvin Glasgow

North Texas Archeological Society Records

A archeological dictionary with common words in Texas archeology, dated for 2003.

The Shetland Site Report, Nolan E. Preston

North Texas Archeological Society Records

A report about the Shetland Site.

Gault School Of Archaeological Research Pamphlet, Gault School Of Archaeological Research

North Texas Archeological Society Records

A pamphlet for the Gault School of Archaeological Research

The Shetland Site, Nolan E. Preston

North Texas Archeological Society Records

A report on The Shetland Site, published in a magazine format.

Dehydration And Traumatic Brain Injury: A Pilot Study Of A Translational Rodent Model Of Conditions In Professional Combat Sports, Alexander S. Martinie, Corey Peacock, Chris Algeri, Bill Kochen

Journal for Sports Neuroscience

Traumatic brain injuries are a widespread public health issue, with athletes being at an increased risk of traumatic brain injury, especially in contact sports. Dehydration and rehydration prior to use of a weight drop served as a model for conditions experienced by professional boxers in a rodent model of traumatic brain injury. Following dehydration, rehydration, and traumatic brain injury procedures, subjects’ symptoms were assessed using the novel object recognition task, sucrose preference test, open field maze, and elevated zero maze. There were significant effects of both dehydration and TBI on time to righting, and there was a significant interaction between …

Two Burials From The Mcann Site, Nolan E. Preston

North Texas Archeological Society Records

A report on two burials located in the Mcann Site and a synopsis of the artifacts found.

From The Desk Of Laurie Moseley, Laurie Moseley

North Texas Archeological Society Records

A draft on a report of a dig site with a note offering revisions.

An Archeological Evaluation Of The Fort Worth Nature Center Gravel Quarry Site, Tarrant County Archeological Society

North Texas Archeological Society Records

A bound draft of the evaluation for the Fort Worth Nature Center Quarry Site.