Digital Commons Network^™

The Mongolian Remodeling And The Structure Of Anoplocephalid Cestode Diversity, Mackenzie Grover

All NMU Master's Theses

Ecological disruption plays an important role in structuring diversity of flora, fauna, and their parasites. At the end of the Eocene, climatic change across Asia resulted in a faunal turnover (the Mongolian Remodeling) as rodents diversified and larger mammals declined. Throughout the Oligocene, the landscape in Asia was characterized by episodic climatic and landscape changes resulting in pulses of rodent diversification. The role of historical ecological disruption in Central Asia in structuring the diversity of parasites of small rodents has not been thoroughly investigated. The hyper-diverse Paranoplocephala species complex (family: Anoplocephalidae) infect rodents throughout the Holarctic and present an opportunity …

Investigating Impacts Of The Mycothiazole Chemotype As A Chemical Probe For The Study Of Mitochondrial Function And Aging., Naibedya Dutta, Joe A Gerke, Sofia F. Odron, Joseph D. Morris, Adam Hruby, Juri Kim, Toni Castro Torres, Sarah J. Shemtov, Jacqueline G. Clarke, Michelle C. Chang, Hooriya Shaghasi, Marissa N. Ray, Maxim Averbukh, Sally Hoang, Maria Oorloff, Athena Alcala, Matthew Vega, Hemal H Mehta, Max A Thorwald, Phillip Crews, Marc Vermulst, Gilberto Garcia, Tyler A. Johnson, Ryo Higuchi-Sanabria

Natural Sciences and Mathematics | Faculty Scholarship

Small molecule inhibitors of the mitochondrial electron transport chain (ETC) hold significant promise to provide valuable insights to the field of mitochondrial research and aging biology. In this study, we investigated two molecules: mycothiazole (MTZ) - from the marine sponge C. mycofijiensis and its more stable semisynthetic analog 8-O-acetylmycothiazole (8-OAc) as potent and selective chemical probes based on their high efficiency to inhibit ETC complex I function. Similar to rotenone (Rote), MTZ, a newly employed ETC complex I inhibitor, exhibited higher cytotoxicity against cancer cell lines compared to certain non-cancer cell lines. Interestingly, 8-OAc demonstrated greater selectivity for cancer cells …

Aged 539 Graduate Internship Report - Live Oak High School, Savannah L. Burnett

Agricultural Education: Graduate Internship Reports

This report documents the implementation and outcomes of a comprehensive agricultural education program at Live Oak High School, aligning with California Career Technical Education (CTE) standards. The project focuses on enhancing student engagement through curriculum development, leadership activities, Supervised Agricultural Experiences (SAEs), and career readiness initiatives. Key components include expanding pathway offerings in horticulture, mechanics, and agricultural sciences, integrating field experiences, and hosting guest speakers to connect students with industry professionals.

Clemson Commencement Program, December 2024, Clemson University

Clemson Commencement Programs

No abstract provided.

Role Of Chemical Priming Agents In Modulating Germination Response To Enhance Crop Eetablishment In Cereal Crops, Shubh Pravat Singh Yadav, Dipesh Kumar Mehata, Sujan Bhandari, Netra Prasad Ghimire, Susmita Bhattarai, Indira Kattel, Shobha Pokhrel, Sangita Bhujel

Extension Publications

Seed priming is a critical pre-sowing strategy to enhance germination and early seedling vigour under diverse environmental conditions. This study evaluated the effects of various priming agents, including Boric acid, DAP, CaCO3, FeCl2, Urea, PEG (5%), CuSO4, MOP, PEG (10%), and ZnSO4, on germination parameters-germination percentage (GP), germination speed (GS), germination energy (GE), and vigour index (VI)-across rice, wheat, and maize varieties. A two factorial experiment was conducted using a completely randomized design, with ANOVA revealing significant effects (p < 0.001) of variety, treatment, and their interaction on germination traits. The results demonstrated that FeCl2 significantly improved germination in rice, particularly for the BRRI Dhan-66 variety, while CaCO3 and PEG treatments showed varying efficacy across crops. In wheat, the Bijaya variety exhibited superior performance with CaCO3 treatment, whereas DAP was more effective for Banganga. Maize showed the highest germination rates overall, with Sundarharaicha-LR1 responding positively to ZnSO4 and boric acid. Correlation and PCA analyses highlighted strong interdependence among germination traits, with GS and GP emerging as robust indicators. Varietal clustering in PCA revealed genetic variability in response to priming agents. This study provides valuable insights into optimizing priming techniques for enhancing seed performance in cereals. The findings emphasize the importance of tailored priming strategies based on crop species and variety to maximize agricultural productivity.

Elucidating The Mechanism Of Interleukin-17a Signaling In The Pathogenesis Of West Nile Virus, Farzana Nazneen

Dissertations

West Nile Virus (WNV), a neurotropic flavivirus transmitted by mosquitoes, is a leading cause of viral encephalitis in the United States and remains a significant public health concern. Unfortunately, no vaccine or therapeutic intervention is available against WNV infection. Previous studies, including ours, demonstrated that interleukin-17A (IL-17A) signaling increases the cytotoxic potential of CD8⁺ T cells to facilitate WNV and parasite clearance; however, the molecular mechanism is not understood. IL-17 receptor C (IL-17RC) is an obligatory co-receptor with IL-17 receptor A (IL-17RA) for signaling induced by IL-17A, IL-17A/F, and IL-17F. In this study, we found that IL-17RC deficient ( …

A Revolution Deferred: Polycrisis And The Failures Of Incremental Change In South Africa, Geoffrey Schneider

Working Papers

No abstract provided.

Creche Herald Vol. 28, No. 4, Rita B. Bocher

Creche Herald

The Winter 2024 publication features nativity sets and personal reflections from members in the organization; information about nativities and nativity exhibits; and information about the Friends of the Creche annual meeting.

Minimizing Take Of Threatened Rattlesnakes And Optimizing Project Review In Se Nebraska, Shaun Dunn, Dan Fogell, Colleen Rothe-Groleau

Nebraska Department of Transportation: Research Reports

The western massasauga (Sistrurus tergeminus) and the timber rattlesnake (Crotalus horridus) are protected under Nebraska Statute 37-801-811 and listed as threatened species. These species occur in the right-of-way (ROW) along several roads in Jefferson, Gage, Pawnee, and Richardson Counties which necessitates the need for added Environmental Review (ER) from Nebraska Department of Transportation (NDOT) staff and onsite surveys prior and during maintenance and construction to roadways. This project sought to minimize ER time, staff time, and increase the knowledge of these species in southeast Nebraska by:

1. Identifying precise locations of western massasauga brumation sites;
2. Mapping travel …

Low Public Awareness Opens Up New Opportunities For Highlighting Milk As An Iodine Dietary Source, Giovanni Niero, Simona Censi, Caterina Mian, Carmen L. Manuelian, Maristela Rovai, Eleni Tsiplakou, Luciana Da Costa, Et.Al

Dairy Science and Food Science Faculty Publications: 2022 to Present

No abstract provided.

The Guardian The Month Of December 2024, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of December 2024. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Epiphany - 7 January 2024, Joe Tedesco

Pastoral Liturgy

No abstract provided.

Full Journal

Pastoral Liturgy

No abstract provided.

Third Sunday Of Advent - 15 December 2024, Gerard Moore

Pastoral Liturgy

No abstract provided.

Mary, Mother Of God - 1 January 2025, Andrew Doohan

Pastoral Liturgy

No abstract provided.

Houge-Janssens Syndrome-1 Associated With Protein Phosphatase 2 Regulatory Subunit B’ Delta And Epilepsy: A Case Report, Dua Saleem, Fizza Akbar, Noor Zeeshan, Rabab Jafry, Salman Kirmani, Sidra Kaleem Jafri

Pakistan Journal of Neurological Sciences (PJNS)

Houge-Janssens syndrome 1 is a rare autosomal dominant disorder with approximately 100 case reports worldwide. Here, we present a case of a Pakistani toddler who presented with epilepsy and developmental delay. Family history was significant with reported and documented developmental delays in both father and elder sister, with subsequent improvement. Trio-whole-genome sequencing (WGS) and Sanger sequencing were performed, revealing a heterozygous LP variant NM_006245.4: c.626A>C, p.(His209Pro) in the girl. The same variant was also identified in her father and sister. This case sheds light on the variability of phenotypic expression amongst affected individuals and recommends the need for further …

Acute Flaccid Myelitis Caused By Enterovirus Infection- A Case Report, Ahmad Bilal, Tipu Sultan, Zia Ur Rehman, Arshad Mehmood, Amber Shabir, Javeria Raza

Pakistan Journal of Neurological Sciences (PJNS)

Enterovirus is a member of the Picornaviridae family, an enterovirus. It is suspected of causing a polio-like disorder called acute flaccid myelitis (AFM). This case report aims to present a 10-year-old boy who presented with neurological manifestations of weakness of lower limbs and urinary retention. He had reduced tone, absent reflexes, and palpable bladder. MRI spine revealed inflammation in grey matter of spinal cord. He was treated with high dose steroids and IVIG but no improvement was observed. Enterovirus was isolated from his stool sample. The patient received supportive care and physiotherapy with gradual improvement after months, having no evidence …

Connecticut Law Review Table Of Contents 57-1

Connecticut Law Review

No abstract provided.

Teaching Constitutional Law In A Crisis Of Judicial Legitimacy, William Baude

Chicago-Kent Law Review

No abstract provided.

From Constitutional Law To Constitutional Change, Steven D. Schwinn

Chicago-Kent Law Review

No abstract provided.

Whatcha Gonna Do When They Come For You? Assessing The Damage Associated With The Rise Of Reality Tv Policing And Proposing Avenues For Accountability And Reform, Danielle Taylor

Chicago-Kent Law Review

No abstract provided.

Energy Intensity Convergence Among Chinese Provinces: A Theil Index Decomposition Analysis, Yifan Wang, Wei Li, Nadia Doytch

Ateneo School of Government Publications

China, the world’s largest carbon emitter, has one of the most stringent provincial emissions reduction programs, incorporated into its Five-Year National Plan to reduce carbon emissions. However, the widening energy intensity gap between provinces poses a great challenge for carbon reduction. In this study, we analyze the convergence of Energy intensity (EIC), i.e., the time-dependent decrease of differences among regional energy intensity over time focusing on a data set of 30 Chinese provinces from 2000 to 2015. Our goal is to identify the provinces that are responsible for the observed divergence in energy intensity and identify the factors causing that …

Impossibility Of Artificial Inventors, Matt Blaszczyk

UC Law Science and Technology Journal

Recently, the United Kingdom Supreme Court decided that only natural persons can be considered inventors. A year before, the United States Court of Appeals for the Federal Circuit issued a similar decision. In fact, so have many of the courts all over the world. This Article analyzes these decisions, argues that the courts got it right, and finds that artificial inventorship is at odds with patent law doctrine, theory, and philosophy. This Article challenges the intellectual property (IP) post-humanists, exposing the analytical and normative perils of their argumentation, and recommends against getting rid of the nominally central place of humans …

Teaching Law Amidst Convulsive Doctrinal Change, Harold J. Krent

Chicago-Kent Law Review

No abstract provided.

Designing An Advanced Gui For A Laser Harp, Matthew Moran

2024 Fall Honors Capstone Projects - Archive

This project presents the design and development of a laser harp, an innovative digital instrument that combines music and technology to inspire interest in STEM education. The harp uses laser beams and phototransistors to simulate the strings of a traditional harp, producing sound when the beams are interrupted. The primary focus of the honors section of this work is a custom-built software interface developed with a graphical user interface (GUI) that allows users to easily adjust settings like note range, volume, and the central part of the show, looping notes. The GUI is designed to be intuitive, making it easy …

Effect Of Hyperbaric Oxygen Therapy (Hbot) On The Proportion Of Splenic Leukocytes During Skeletal Muscle Regeneration, Hetvi Patel

2024 Fall Honors Capstone Projects - Archive

Hyperbaric oxygen therapy (HBOT) can accelerate the regeneration of skeletal muscle after injury and improve overall recovery. Certain cells of the spleen are increased during muscle regeneration; however, the effect of HBOT on splenic cells during muscle regeneration is not well understood. In other experimental models, HBOT proliferates the proportion of splenic cells. In this study, eight male and nine female mice sustaining crush muscle injuries underwent HBOT at 1.5 atmospheres absolute for 60 min or normobaric hyperoxia (100% O₂) for 60 min within 2-6 hours of injury for 4 days. The mice were then euthanized at 4- …

Investigating The Acute Physiological Effects Of Effluent Crystal Violet On The Freshwater Bioindicator Daphnia Pulex, Hoang K. Ho

2024 Fall Honors Capstone Projects - Archive

This study examines the effects of acute exposure to crystal violet (CV) on the freshwater zooplankton Daphnia pulex in response to growing concerns over synthetic dyes from industrial runoff in aquatic ecosystems. The primary objective is to assess CV's impact on D. pulex's heart rate, mobility, morphology, and lethality via a series of acute exposure tests. 48-h acute toxicity (0-2000 μg/L), 48-h immobilization (0-180 μg/L), and 9-h heart rate (0-2,000 μg/L) tests were conducted using third-generation daphnids, followed by stereomicroscopic examination and statistical analysis. Results showed increasing mortality and decreasing mobility and heart rate with increasing CV concentration; the …

Determining Evolutionary Conservation Of Mhc-E And Vista Interaction, Julia Glenn

2024 Fall Honors Capstone Projects - Archive

Research in the Weidanz laboratory is focused on cellular molecules which inhibit immune activation, known as immune checkpoints. One example is HLA-E, which can modulate immune responses at homeostasis or in the context of cancer. HLA-E typically acts by presenting short canonical peptides (VL9s) and binding to CD94/NKG2A receptors on NK cells and T cells. The Weidanz laboratory’s research has found that in the absence of these VL9 peptides, HLA-E binds to another immune checkpoint, VISTA, instead of CD94/NKG2A. Therefore, the HLA-E/VISTA interaction is peptide-dependent. The current study aims to determine if this peptide-dependent interaction is evolutionarily conserved using the …

The Process Of Creating A Visual Identity System From Scratch, Daisy L. Macias

2024 Fall Honors Capstone Projects - Archive

A visual identity system is a collection of design elements that work together to maintain consistency through various applications. A study of iconic brands clarifies how a design is successfully executed. This creative project began with selecting an industry, writing a creative brief, curating mood boards for visual research, brainstorming a brand name, creating a set of graphics that aid the brand identity, and implementing these graphics together to create a successful visual identity system. For this project, an indie cinema was selected, and based on existing visual research for this industry, the design style referenced contemporary art. The final …

Forging A Niche: Preparing Models For The Animation Pipeline In A Changing Industry, Grayson Wiles

Master of Fine Arts in Digital Media Culminating Experience

This culminating experience shows a complete and comprehensive skill set in the animation pipeline using three diverse 3D models: Baba Yaga, the Orc, and the Roo Fighter. This work includes reposing, retopology, UV mapping, texturing, and rigging. Each model was selected for its unique attributes and challenges, showing versatility in anatomy, efficiency, and communication. Spurred on by a dubious job market and the improvement of AI tools, this project showcases the author's capabilities to fulfill multiple roles in the animation pipeline, providing an advantage for employment in the digital media industry.