Digital Commons Network^™

Silvered Palace, Sam Kreiger

Philomathean

No abstract provided.

Voice Of Magic, Kiya Whitaker

Philomathean

No abstract provided.

Spartan Daily, December 5, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 42

The Indiana Statesman, December 5, 2024, Indiana State University

Student Newspaper

Finals Week Schedule; Tips and tricks for finals; ‘Wicked’ defies expectations

Education Policy Committee Minutes December 05, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports
• Other Business
• Adjourn: 3:30pm

Curriculum Subcomittee Minutes December 5, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:02pm

Education Policy Committee Agenda December 05, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports
• Other Business
• Adjourn: 4:00pm

Bile Duct Ligation-Induced Cirrhosis Does Not Alter The Blood-Brain Barrier Permeability To Sucrose In Rats, Mohammad K. Miah, Ulrich Bickel, Reza Mehvar

Pharmacy Faculty Articles and Research

Contradictory results have been reported about the effects of liver diseases on the blood-brain barrier (BBB) permeability to markers. For instance, both an increase and no change in the BBB permeability to BBB markers sodium fluorescein and Evans blue have been reported in experimental cholestasis induced by bile duct ligation (BDL) in rats. These contradictory effects might be due to inherent limitations of these markers and/or methodological issues. Here, we investigated the time course of the impact of BDL in rats on BBB permeability using a recently developed stable isotope labeled marker [¹³C]sucrose, which is expected to be …

Butterfly Peacock Bass (Cichla Ocellaris), Samuel K. Zellefrow, David Kerstetter, John Nichols

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

The Comment, December 5, 2024, Bridgewater State University

The Comment

No abstract provided.

General Education Subcommittee Agenda December 05, 2025, Utah State University

Educational Policies Committee

• Call to Order
• Approval of Minutes
• Course Approvals/Removals/Syllabi Approvals
• New Business
• Additional Items
• Adjourn: 9:30am

Curriculum Subcommittee Agenda December 05, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:00pm

Animals In Conflict – Part Ii: Animal Protection Organizations; Conflict And Disaster Response Work, Janice Cox, Jackson Zee

WellBeing News

Animals were commonly overlooked in disaster responses in the 20th century but that is changing in the 21st.

A Case Of Dallisgrass Staggers In Oklahoma, Stephen T. Lee Phd, Giselle Cino Ozuna D.V.M., Ph.D., Diplomate Acvp, Adriana Villasenor Dvm, Daniel Cook Phd

Poisonous Plant Research (PPR)

Dallisgrass is a warm-season, perennial forage found in pastures across the southeastern United States. Seed heads of dallisgrass are susceptible to ergot infection resulting in production of several tremorgenic indole-diterpene alkaloids such as paspalinine, paspalitrem A, and paspalitrem B. Herein, we report a clinical case of “dallisgrass staggers” in Oklahoma beef cows resulting in 31% morbidity and 5% mortality. Clinical signs were first observed within 36 hours of exposure to a new pasture, and included shaking, whole body tremors, staggering, swaying and wobbling when walking, falling down, and hyperexcitability. Tremorgenic indole diterpene alkaloids were detected from ergotized seed heads …

Targeting The Cholesterol Storage Enzyme Acat1/Soat1 In Brain Cells And Mouse Model: A Novel Approach To Address Aging And Apoe4-Related Neuroinflammation, Thao Nguyen Phuong Huynh Krumeich

Dartmouth College Ph.D Dissertations

Alzheimer’s Disease (AD) is a progressive neurodegenerative disease that significantly impacts nearly 7 million people in the United States. AD is characterized by the deposition of amyloid beta (Ab) plaque, tau neurofibrillary tangles (NFTs), lipids granules, and neuroinflammation. Age and apolipoprotein E4 (APOE4) are the two biggest risk factors for AD. Recent AD therapeutic development has mostly benefited the patient population with milder symptoms while causing serious side effects in APOE4 carriers, leaving the most impacted patients’ group - aged APOE4 carriers with no treatment option. With the increasing aging population, there is an urgent need for a …

Faculty Senate Roster 2024-2025, Faculty Senate

Faculty Senate Documents

A list distributed by Faculty Senate of members of the governance body and affiliated committees.

“Arrogance For Cruelty”: What Builds Exclusion Into The Canada Disability Benefit, Thaddeus Hwong

Osgoode Hall Law Journal

The vision animating the Canada Disability Benefit exemplifies “arrogance for cruelty” in public policymaking. What could be the start of doing so much is just the end of doing so little—something is done, so nothing more will need to be done. Dangling hopes and then crushing them is cruel. What perpetuates such policymaking cruelty is a manifest complacency, asserting that what is usually done is what should be done, and so it is the best that can be done. Deifying such inertia, which fortifies inadequacies despite what the disability community has to say, is arrogant. Using the limited amount of …

Cellular Trafficking And Fate Mapping Of Cells Within The Nervous System After In Utero Hematopoietic Cell Transplantation, Matthew T Grant, Hemanth Ramesh Nelvagal, Maria Tecos, Amal Hamed, Kerry Swanson, Jonathan D Cooper, Jesse D Vrecenak

2020-Current year OA Pubs

In utero hematopoietic cell transplantation (IUHCT) utilizes fetal immune tolerance to achieve durable chimerism without conditioning or immunosuppression during a unique window in fetal development. Though donor cells have been observed within the nervous system following in utero injection, the timeline and distribution of cellular trafficking across the blood-brain barrier following IUHCT is not well understood. We injected 20 × 10

Ices Roadmap For Marine Recreational Fisheries (Mrf), International Council For The Exploration Of The Sea (Ices), Karina L. Ryan

Fisheries Research Articles

Purpose of the roadmap

The overarching goal of this roadmap is to guide the development of robust marine recreational fisheries (MRF) assessments through data and methodological improvements, in line with current and future management needs. To address the requirements of the policy and legislative instruments in relation to MRF and to plan future steps in ICES, there is need to further improve and operationalize the required MRF dataflows and assessment procedures. Better integration of MRF into advice is in line with ICES vision and mission alongside its advisory framework and principles. This will assist not only managers but also the …

Valve Train Design And Material Testing, Luis Luna

Publications and Research

In automotive engineering, CAD software like SolidWorks enables engineers to design and simulate mechanical components efficiently, reducing the need for extensive prototyping. This project examines the rocker arm's performance and durability within a valve train system. Components like pushrods, camshafts, and rocker arms control air intake and exhaust timing. Due to its high-impact motion and exposure to elevated temperatures, the rocker arm endures considerable wear. This study uses SolidWorks and Finite Element Analysis (FEA) to analyze the rocker arm's stress, deformation, and wear potential during camshaft movement. Material testing and motion analysis results provide insights into improving the durability of …

Kenyon Collegian - December 5, 2024

The Kenyon Collegian

No abstract provided.

Liar-Dependent Gene Expression Contributes To Antimicrobial Responses In Group A, Luis Alberto Vega, Misú Sanson-Iglesias, Piyali Mukherjee, Kyle D Buchan, Gretchen Morrison, Anne E Hohlt, Anthony R Flores

Faculty, Staff and Student Publications

The ability to sense and respond to host defenses is essential for pathogen survival. Some mechanisms involve two-component systems (TCSs) that respond to host molecules, such as antimicrobial peptides (AMPs), and activate specific gene regulatory pathways to aid in survival. Alongside TCSs, bacteria coordinate cell division proteins, chaperones, cell wall sortases, and secretory translocons at discrete locations within the cytoplasmic membrane, referred to as functional membrane microdomains (FMMs). In group A Streptococcus (GAS), the FMM or “ExPortal” coordinates protein secretion, cell wall synthesis, and sensing of AMP-mediated cell envelope stress via the LiaFSR three-component system. Previously, we showed that GAS …

Evaluating The Role Of Wetland Habitat Features In Shaping Bird Residence Patterns For Effective Conservation Strategies, Josie Lester

Student Scholar Symposium Abstracts and Posters

As climate change continues to impact ecosystems worldwide, wetlands have been disproportionately affected because they are close to human settlements. Wetland degradation is an essential focus for habitat restoration because increased connectivity of these sensitive habitats can significantly improve ecosystem function. The Los Cerritos Wetland (LCW) is an urban wetland fragment in Southern California in the pre-tidal restoration stage. Neighboring waterways are home to many animals, including sea turtles, fishes, and birds. We set out to understand the current use of LCW habitats pre-restoration to better track the impacts of tidal restoration on this wetland fragment. We focused on native …

Fall 2024 Student Scholar Symposium Abstract Volume, Chapman University Center For Undergraduate Excellence

Student Scholar Symposium Abstracts and Posters

No abstract provided.

Potential Of Ecklonia Maxima As A Feed Supplement In Aquafeed: A Review, Tlou Kevin Ngoepe, Moses Okpeku, Esau Matthews Mbokane, Molatelo Junior Madibana, Sahya Maulu, Selaelo Jaqueline Mphalo, Ronewa Lieborn Nemakhavhani, Sithembile Zenith Ndlela

School of Biological and Marine Sciences

This review examines the potential of Ecklonia maxima, a brown seaweed, as a sustainable feed supplement in aquaculture. With the industry facing pressure to adopt environmentally friendly practices, E. maxima offers promise due to its bioactive compounds that promote growth and health in aquatic organisms. Studies have shown that dietary supplementation with E. maxima improves fish growth rates, feed conversion efficiency, and nutrient retention. The seaweed’s bioactive compounds, including phlorotannins and fucoidans, enhance digestibility, modulate gut health, and stimulate immune responses. This review assesses the impact of E. maxima supplementation on fish growth performance and feed utilization, considering factors like …

Natural Medicine Use In Costa Rica, Elizabeth Krol

Honors Theses

This study explores the role of natural medicine in Costa Rican culture, while focusing on its historical, cultural, and clinical significance. With a literature review, ethnobotanical research, and a study abroad experience, this paper highlights the integration of natural, herbal medicine into modern healthcare. Costa Rica’s rich biodiversity, with its varied microclimates and abundant medicinal plants, forms a strong foundation for traditional herbal medicine. Indigenous groups such as the BriBri and Cabécar contributed significantly to this legacy, which has evolved through interactions with European and Afro-Caribbean populations.

Research emphasizes the cultural importance of herbal medicine within the “Pura Vida” lifestyle, …

Amniotic Fluid-Derived Stem Cells: Potential Factories Of Natural And Mimetic Strategies For Congenital Malformations, Cristiane S R Fonteles, Julia Enterria-Rosales, Ying Lin, John W Steele, Ramiro A Villarreal-Leal, Jing Xiao, Daniel I Idowu, Beck Burgelin, Bogdan J Wlodarczyk, Richard H Finnell, Bruna Corradetti

Faculty, Staff and Students Publications

BACKGROUND: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedures. Here, we present naturally occurring exosomes (EXOs) isolated from amniotic fluid-derived MSCs (AF-MSCs) and their mimetic analogs (MIMs) as viable, reproducible, and stable alternatives. These nanovesicles present a minimally invasive therapeutic option, addressing the limitations of MSC-based treatments while retaining therapeutic efficacy.

METHODS: MIMs were generated from AF-MSCs by combining sequential filtration steps through filter membranes with different porosity and size exclusion …

Montana Kaimin, December 5, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

3d Genome Topology Distinguishes Molecular Subgroups Of Medulloblastoma, John J Y Lee, Michael J Johnston, Hamza Farooq, Huey-Miin Chen, Subhi Talal Younes, Raul Suarez, Melissa Zwaig, Nikoleta Juretic, William A Weiss, Jiannis Ragoussis, Nada Jabado, Michael D Taylor, Marco Gallo

Faculty, Staff and Students Publications

Four main medulloblastoma (MB) molecular subtypes have been identified based on transcriptional, DNA methylation, and genetic profiles. However, it is currently not known whether 3D genome architecture differs between MB subtypes. To address this question, we performed in situ Hi-C to reconstruct the 3D genome architecture of MB subtypes. In total, we generated Hi-C and matching transcriptome data for 28 surgical specimens and Hi-C data for one patient-derived xenograft. The average resolution of the Hi-C maps was 6,833 bp. Using these data, we found that insulation scores of topologically associating domains (TADs) were effective at distinguishing MB molecular subgroups. TAD …

Integrating Drug Target Information In Deep Learning Models To Predict The Risk Of Adverse Events In Patients With Comorbid Post-Traumatic Stress Disorder And Alcohol Use Disorder, Oshin Miranda, Xiguang Qi, M Daniel Brannock, Ryan Whitworth, Thomas R Kosten, Neal David Ryan, Gretchen L Haas, Levent Kirisci, Lirong Wang

Faculty, Staff and Students Publications

Background/Objectives: Comorbid post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) patients are at a significantly higher risk of adverse outcomes, including opioid use disorder, depression, suicidal behaviors, and death, yet limited treatment options exist for this population. This study aimed to build on previous research by incorporating drug target information into a novel deep learning model, T-DeepBiomarker, to predict adverse outcomes and identify potential therapeutic medications.

Methods: We utilized electronic medical record (EMR) data from the University of Pittsburgh Medical Center (UPMC), analyzing 5565 PTSD + AUD patients. T-DeepBiomarker was developed by integrating multimodal data, including lab results, drug …