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Corporate Personhood, Corporate Rights, And The Contingency Of Corporate Law, Christopher Bruner Jan 2025

Corporate Personhood, Corporate Rights, And The Contingency Of Corporate Law, Christopher Bruner

Scholarly Works

Corporate personhood and corporate rights are co-constitutive in nature, meaning that they are mutually constructed – there is no singular, one-way causal path between a conception of corporate personhood and a conception of corporate rights. Consequently, modes of reasoning that purport to deduce the substance and extent of corporate rights from the mere fact of corporate personhood are logically circular. Although the relationship between corporate personhood and corporate rights is real and significant, this relationship cannot, in and of itself, comprehensively specify the content of corporate rights; their substance can only be specified by reference to external normative criteria. The …


Food Finding Ability Does Not Predict Annual Survival In Winter Resident Birds, Aidan Hand Jan 2025

Food Finding Ability Does Not Predict Annual Survival In Winter Resident Birds, Aidan Hand

Honors Program: Senior Projects (Public)

Small non-migratory birds in temperate locations face many challenges to survive the winter. They must be able to find enough food, which is in decreased supply, to fuel the energetic demands of staying warm. Prior work has demonstrated that birds show individual variation in their foraging behaviors that could contribute to the discovery of new foraging patches, such as novel environment exploration. A better ability to discover new food sources could increase a bird’s chance of surviving the winter by increasing its access to new food patches. To test this hypothesis, we used radio frequency identification (RFID)-enabled bird feeders to …


“Take Eight Bits And Call Me In The Morning” Video Games, Well-Being, And The Psychology Of Nostalgia, Nicholas Bowman Jan 2025

“Take Eight Bits And Call Me In The Morning” Video Games, Well-Being, And The Psychology Of Nostalgia, Nicholas Bowman

Media Studies - All Scholarship

For nearly 60 years, video games have arrested the attention of players, inviting us to interact and interface with on-screen content. More than just short-term entertainment experiences, video games are part of a broader cultural milieu—they are the most profitable media entertainment sector (global revenues nearly $400 billion USD in 2023) with more than 3.5 billion players globally (Clement, 2023). Similar to other entertainment media, some video game intellectual properties have transcended generations and, in many cases, grown beyond the medium itself: common cultural touchstones include Super Mario Bros. and Sonic the Hedgehog, along with seemingly endless subcultures of devoted …


What Lawyers Could Learn From The Corporate Practice Of Medicine, Melissa D. Mortazavi Jan 2025

What Lawyers Could Learn From The Corporate Practice Of Medicine, Melissa D. Mortazavi

Faculty Articles

Proponents of the United States’ domestic experiments in non-lawyer ownership (NLO) of legal practice justify them in terms of increasing “access to justice.” But what if opening ownership of legal practice to investment capital only exacerbates market failures (leading to further consolidation and increased costs to clients), while also compromising professional autonomy and fiduciary duty? The legal profession must be clear-eyed about who are the real winners and losers of such a shift and avoid being blinded by wishful thinking. Prominent legal scholars have repeatedly touted NLO as a solution to the access to justice crisis. However, there is scant …


Homelands Not Graveyards, M. Alexander Pearl Jan 2025

Homelands Not Graveyards, M. Alexander Pearl

Faculty Articles

Within the last five years, the U.S. Supreme Court has taken up several transformative cases affecting Native nations and federal Indian law jurisprudence. The Supreme Court’s decision in Arizona v. Navajo Nation is no different. This Article examines that decision and situates it within that legal history as well as the realities of present-day water resource availability. While recent decisions have shown the Court’s willingness to confirm fundamental components of federal Indian law, such as the legal tests for determining the persistence of reservation and the authority of Congress to enact the Indian Child Welfare Act, the Court’s examination of …


An Unreliable Reporter, Jon J. Lee Jan 2025

An Unreliable Reporter, Jon J. Lee

Faculty Articles

As part of the legal profession’s tradition of self-regulation, attorneys have an ethical obligation to ensure that those within it are fit to practice. Given the gravity associated with accusing another lawyer of misconduct, it is not surprising that many are reticent to speak up. But what would happen if attorneys were pressured to vigorously pursue sanctions against their opponents, even if those sanctions may be unwarranted? President Trump’s recently-issued memorandum arguably does just that, mandating the Attorney General to seek court and disciplinary sanctions for lawyers and law firms that appear to violate ethics rules. This Essay explains how …


Zorro: Everyperson's Moral Vigilante, Stephen E. Henderson Jan 2025

Zorro: Everyperson's Moral Vigilante, Stephen E. Henderson

Faculty Articles

Zorro (Amazon 2024) is hundreds of years in the making—from medieval ballads of Robin Hood; to the fiction of Alexandre Dumas, Baroness Orczy, and the legend of Mexican bandits; to the Johnston McCulley 1919 original; to comics like Daredevil and Batman; to scores of Zorro derivatives from the minds of McCulley, Walt Disney, and many others. At this point, it would be impossible to identify and duly credit the countless inspirations that together form this early-California vigilante. But such rich heritage might provide something more than literature and entertainment: if there is an everyperson’s conception of a moral vigilante, Zorro …


Space Resource Development And Property - Clarifying Usufruct, Jeremy A. Kent Jan 2025

Space Resource Development And Property - Clarifying Usufruct, Jeremy A. Kent

Journal of Air Law and Commerce

This article examines competing legal frameworks for governing property rights in outer-space resources through a comparative analysis of two distinct approaches: the rule of capture and the concept of usufruct. The increasing interest in commercial space activities, such as mining the Moon and asteroids, has raised questions about the legal frameworks governing property rights in space resources. The growing challenge is that while the Outer Space Treaty (OST) serves as the foundation for space law, it does not explicitly address property rights in the resources humankind increasingly can extract from the space domain.

The rule of capture is a legal …


Dangers From Regulatory Vacuums In Outer, Inner, And Near Space, Rob Frieden Jan 2025

Dangers From Regulatory Vacuums In Outer, Inner, And Near Space, Rob Frieden

Journal of Air Law and Commerce

Space, “the final frontier,” has become an attractive but increasingly risky market for both public and private investments. Gold rush enthusiasm anticipates solutions to the digital divide via small low earth orbiting satellites, extraction of valuable minerals from asteroids, a vibrant space launch and tourism industry, and expanding earth observation opportunities. Such entrepreneurial boldness juxtaposes with a severe lag in government oversight, consumer safeguards, and essential operational guardrails. The ambitious plans of Elon Musk and other space entrepreneurs could fail—despite recent market success—as SpaceX’s plans for 148 rocket launches in 2024.

Without substantial refinement of global space treaties and effective …


Strengthening Ecosystem Sustainability And Climate Resilience Through Integrative Nature-Based Solutions In Bontioli Natural Reserve, West African Drylands, Issaka Abdou Razakou Kiribou, Kangbéni Dimobe, Sintayehu W. Dejene Jan 2025

Strengthening Ecosystem Sustainability And Climate Resilience Through Integrative Nature-Based Solutions In Bontioli Natural Reserve, West African Drylands, Issaka Abdou Razakou Kiribou, Kangbéni Dimobe, Sintayehu W. Dejene

All Rsif Scholars' Publications

Natural reserves in the West African drylands play a critical role in sustaining livelihoods and preserving ecological integrity. However, these ecosystems face growing threats from climate variability and anthropogenic pressure. This study assesses the potential of Nature- based Solutions (NbSs) to enhance climate resilience and mitigate human-induced degra- dation in Bontioli Natural Reserve (BNR), one of the region’s key biodiversity hotspots. We employed an integrated approach combining ecological assessments, climate and anthro- pogenic pressures analysis, and participatory governance framework. Generalized additive modeling (GAM) is applied to assess the long-term vegetation response to climate stressors. A conceptual framework that integrates climate …


Spatiotemporal Land Use Changes Dynamics Impacts On Natural Reserves In West African Dryland: Drivers, Carbon Emissions And Climate Change Implications, Issaka Abdou Razakou Kiribou, Kangbéni Dimobe, Charles Lamoussa Sanou, Sintayehu W. Dejene Jan 2025

Spatiotemporal Land Use Changes Dynamics Impacts On Natural Reserves In West African Dryland: Drivers, Carbon Emissions And Climate Change Implications, Issaka Abdou Razakou Kiribou, Kangbéni Dimobe, Charles Lamoussa Sanou, Sintayehu W. Dejene

All Rsif Scholars' Publications

Land use change (LUC), primarily driven by anthropogenic pressure, poses a major threat to West African drylands’ vegetation. As critical indicators of ecosystem sustainability, LUC patterns reflect how human activities alter carbon dynamics and climate vulnerability. This systematic review analyzes the spatial and temporal dynamics of LUC impacts on natural reserves. Using targeted keywords, 18 peer-reviewed articles and institutional reports were synthesized to assess LUC patterns, identify key biophysical and socio-economic drivers, and evaluate carbon and climate implications. Findings show substantial losses of natural ecosystems due to land conversion, deforestation, and soil degradation. Between 1975 and 2013, Sahelian savanna, woodland, …


Energy Efficiency In The Building Sector In Burkina Faso: Literature Review, Swot Analysis, And Recommendations, Bazam Amonet Ouoba Nebie, Abdou Lawane, Césaire Hema, Monica Siroux Jan 2025

Energy Efficiency In The Building Sector In Burkina Faso: Literature Review, Swot Analysis, And Recommendations, Bazam Amonet Ouoba Nebie, Abdou Lawane, Césaire Hema, Monica Siroux

All Rsif Scholars' Publications

In Burkina Faso, increasing access to electricity requires the optimized management of energy consumption in buildings and the implementation of regional and national regulations. These regulations have been implemented to promote energy efficiency in the building sector. However, they do not yet seem to have produced the expected results. Conducting a study could help identify the shortcomings related to energy efficiency and guide future research toward sustainable solutions. To date, no such study has been carried out. Therefore, this research aims to analyze the causes of these shortcomings, understand the gaps in the literature, and identify prospects for implementing energy …


Assessment Of Bio-Security Knowledge, Attitude And Hygienic Practices Among Smallholder Chicken Farmers In Southern Mozambique, Noémia André Mugabe, Jamal Kussaga, Abdulsudi Issa-Zacharia Jan 2025

Assessment Of Bio-Security Knowledge, Attitude And Hygienic Practices Among Smallholder Chicken Farmers In Southern Mozambique, Noémia André Mugabe, Jamal Kussaga, Abdulsudi Issa-Zacharia

All Rsif Scholars' Publications

The production of broiler chickens in intensive systems struggles to maintain hygiene in production, despite contributing to combating malnutrition, generating employment, and increasing family income, especially in developing countries. Using a structured questionnaire survey, a cross-sectional study was carried out among 395 smallholder farmers to evaluate their knowledge, attitudes, and practices related to farm biosecurity in urban and peri-urban areas of Mozambique and determine the factors affecting KAP (knowledge, attitude, and practice) levels. Data were analyzed using Statistical Package for Social Science (SPSS) (IBM version 27). The findings indicate that education level and training significantly influence (p < 0.001) food safety in terms of biosecurity knowledge, attitudes, and practices. Smallholders who attended food safety training exhibited positive attitudes (95.5%, mean score of 89.71 ± 10.1) in contrast to those who did not participate in training (74.8%, mean score of 79.91 ± 9.68). Additionally, washing hands with soap before and after using the toilet and wearing protective clothing during chicken husbandry were significantly associated with education level (χ² = 15.345, P = 0.018); those with informal education were 34% less likely to have a negative attitude toward food safety compared to those with high education. A significant correlation (p < 0.01) was observed between residence area, training, and biosecurity knowledge, attitude, and practice. Because smallholders lack training, hygiene expertise, and biosecurity practices on their farms, this study concluded that they pose a risk to public health and food safety. To maintain consumer health and guarantee food safety, farmers should properly dispose of waste, including dead chickens, and receive continuous training in excellent biosecurity measures on the farm


Antibiotic Use And Antimicrobial Resistance: Knowledge, Attitudes, And Practices Among Smallholder Chicken Farmers In Southern Mozambique, Noemia Andre Mugabe, Jamal Kussaga, Abdulsudi Issa-Zacharia Jan 2025

Antibiotic Use And Antimicrobial Resistance: Knowledge, Attitudes, And Practices Among Smallholder Chicken Farmers In Southern Mozambique, Noemia Andre Mugabe, Jamal Kussaga, Abdulsudi Issa-Zacharia

All Rsif Scholars' Publications

Intensive production systems face challenges in treating individual chickens due to the large number of animals, resulting in the indiscriminate use of antibiotics as the only alternative. The use of antibiotics in poultry production has adverse effects on humans, as prolonged consumption of contaminated meat can lead to the development of antibiotic resistance in intestinal bacteria. A cross-sectional survey involving 395 smallholder farmers was conducted through face-to-face interviews to assess knowledge, attitudes, and practices (KAP) regarding antibiotic use in urban and peri-urban areas of Southern Mozambique. Data were analyzed using SPSS version 27. The findings revealed that 60% of respondents …


Identification Of Potential Vectors And Detection Of Rift Valley Fever Virus In Mosquitoes Collected Before And During The 2022 Outbreak In Rwanda, Isidore Nsengimana, Emmanuel Hakizimana, Jackie Mupfasoni, Jean Nepomuscene Hakizimana, Augustino A. Chengula, Christopher J. Kasanga, Gillian Eastwood Jan 2025

Identification Of Potential Vectors And Detection Of Rift Valley Fever Virus In Mosquitoes Collected Before And During The 2022 Outbreak In Rwanda, Isidore Nsengimana, Emmanuel Hakizimana, Jackie Mupfasoni, Jean Nepomuscene Hakizimana, Augustino A. Chengula, Christopher J. Kasanga, Gillian Eastwood

All Rsif Scholars' Publications

Rift Valley fever virus (RVFV) is an emerging mosquito-borne arbovirus of One Health importance that caused two large outbreaks in Rwanda in 2018 and 2022. Information on vector species with a role in RVFV eco-epidemiology in Rwanda is scarce. Here we sought to identify potential mosquito vectors of RVFV in Rwanda, their distribution and abundance, as well as their infection status. Since an outbreak of RVF occurred during the study period, data were obtained both during an interepidemic period and during the 2022 Rwanda RVF outbreak. Five districts of the eastern province of Rwanda were prospected using a combination of …


Artificial Intelligence-Driven Near-Infrared Spectrophotometry Model For Rapid Quantification Of Anti-Nutritional Factors In Soybean (Glycine Max.), Noberto Jose Palange, Tonny Obua Tonny Obua, Julius Pyton Sserumaga, Enoch Wembabazi, Mildred Ochwo-Ssemakula, Ephraim Nuwamanya, Isaac Onziga Dramadri, Moses Matovu, Richard Edema, Phinehas Tukamuhabwa Jan 2025

Artificial Intelligence-Driven Near-Infrared Spectrophotometry Model For Rapid Quantification Of Anti-Nutritional Factors In Soybean (Glycine Max.), Noberto Jose Palange, Tonny Obua Tonny Obua, Julius Pyton Sserumaga, Enoch Wembabazi, Mildred Ochwo-Ssemakula, Ephraim Nuwamanya, Isaac Onziga Dramadri, Moses Matovu, Richard Edema, Phinehas Tukamuhabwa

All Rsif Scholars' Publications

Anti-nutritional factors can impact soybean nutrient bioavailability when consumed by monogastric animals. However, conventional methods available for quantifying anti-nutritional factors such as phytate and trypsin inhibitors in feeds are laboratory-intensive, time-consuming, expensive, and error-prone. This study developed near-infrared spectrophotometry (NIRS)-based models to quantify phytate and trypsin inhibitors in soybean. Thus, a set of 190 soybean genotypes assayed through conventional wet chemistry was used as a reference for model development and cross-validation. Using a benchtop NIR instrument (DS2500), spectra readings between 400 and 2500 nm were taken from each soybean sample. Mean values for phytate and total trypsin inhibitors (TTI) were …


Advancing Sustainable Practices: Integrated Pedological Characterization And Suitability Assessment For Enhanced Irish Potato Production In Tsangano And Angónia Districts Of Tete Province, Mozambique., Tamara Jose Sande, Balthazar Michael Msanya, Hamisi Juma Tindwa, Alessandra Mayumi Tokura Alovisi, Johnson M. Semoka, Mawazo Shitindi Jan 2025

Advancing Sustainable Practices: Integrated Pedological Characterization And Suitability Assessment For Enhanced Irish Potato Production In Tsangano And Angónia Districts Of Tete Province, Mozambique., Tamara Jose Sande, Balthazar Michael Msanya, Hamisi Juma Tindwa, Alessandra Mayumi Tokura Alovisi, Johnson M. Semoka, Mawazo Shitindi

All Rsif Scholars' Publications

Irish potato (Solanum tuberosum) is a critical crop for food security and economic growth in Tsangano and Angónia Districts, Central Mozambique. Challenges like inconsistent yields and variable quality are often linked to suboptimal soil conditions, which limit production. This study aimed to classify and evaluate the suitability of soils for potato cultivation in Tete Province, where detailed soil assessments remain limited. Four pedons—TSA-P01 and TSA-P02 in Tsangano and ANGO-P01 and ANGO-P02 in Angónia—were examined for bulk density, texture, pH, organic carbon, and nutrient content using a combination of pedological methods and laboratory soil analysis. To determine each site’s potential for …


Fermentation, Handling And Claimed Therapeutic Effects Of Dhanaan: An Ethiopian Fermented Camel Milk, Tiruha Habte Karssa, Jamal B. Kussaga, Teresa Lemsaddek Lemsaddek, Jovin K. Mugula Jan 2025

Fermentation, Handling And Claimed Therapeutic Effects Of Dhanaan: An Ethiopian Fermented Camel Milk, Tiruha Habte Karssa, Jamal B. Kussaga, Teresa Lemsaddek Lemsaddek, Jovin K. Mugula

All Rsif Scholars' Publications

Dhanaan is a spontaneously fermented camel milk that is popular in the Somali regional state of Ethiopia and plays a sig- nificant role in the livelihoods of pastoral communities. This study aimed to investigate traditional fermentation methods of dhanaan in these communities. Four districts, namely, Gursum, Shabelle, Degehabur, and Birqot, were purposively selected on the basis of camel rearing, camel milk production, and consumption. A cross-sectional survey of traditional fermentation methods, handling, utilization, and the claimed therapeutic effects of dhanaan was conducted using both open- and closed- ended questions in the districts. The traditional preparation of dhanaan involves spontaneous fermentation …


Ganglioside Gd2 Contributes To A Stem-Like Phenotype In Intrahepatic Cholangiocarcinoma, Antonella Mannini, Mirella Pastore, Alessia Giachi, Margherita Correnti, Elena Spínola Lasso, Tiziano Lottini, Benedetta Piombanti, Ignazia Tusa, Elisabetta Rovida, Cédric Coulouarn, Jesper B Andersen, Monika Lewinska, Claudia Campani, V Lokesh Battula, Bin Yuan, Massimo Aureli, Emma V Carsana, Caterina Peraldo Neia, Paola Ostano, Alessia Tani, Daniele Nosi, Anna Vanni, Laura Maggi, Luca Di Tommaso, Giuseppina Comito, Stefania Madiai, Annarosa Arcangeli, Fabio Marra, Chiara Raggi Jan 2025

Ganglioside Gd2 Contributes To A Stem-Like Phenotype In Intrahepatic Cholangiocarcinoma, Antonella Mannini, Mirella Pastore, Alessia Giachi, Margherita Correnti, Elena Spínola Lasso, Tiziano Lottini, Benedetta Piombanti, Ignazia Tusa, Elisabetta Rovida, Cédric Coulouarn, Jesper B Andersen, Monika Lewinska, Claudia Campani, V Lokesh Battula, Bin Yuan, Massimo Aureli, Emma V Carsana, Caterina Peraldo Neia, Paola Ostano, Alessia Tani, Daniele Nosi, Anna Vanni, Laura Maggi, Luca Di Tommaso, Giuseppina Comito, Stefania Madiai, Annarosa Arcangeli, Fabio Marra, Chiara Raggi

Faculty, Staff and Student Publications

BACKGROUND & AIMS: GD2, a member of the ganglioside (GS) family (sialic acid-containing glycosphingolipids), is a potential biomarker of cancer stem cells (CSC) in several tumours. However, the possible role of GD2 and its biosynthetic enzyme, GD3 synthase (GD3S), in intrahepatic cholangiocarcinoma (iCCA) has not been explored.

METHODS: The stem-like subset of two iCCA cell lines was enriched by sphere culture (SPH) and compared to monolayer parental cells (MON). GS profiles were evaluated by chromatography, after feeding with radioactive sphingosine. Membrane GD2 expression was evaluated by FACS, and the expression of enzymes of GS biosynthesis was analysed by RT-qPCR. The …


18 Kda Translocator Protein (Tspo) Is Upregulated In Rat Brain After Peripheral Nerve Injury And Downregulated By Diroximel Fumarate, Rafael A Cazuza, Sever M Zagrai, Anamaria R Grieco, Thomas D Avery, Andrew D Abell, Hsiao-Ying Wey, Marco L Loggia, Peter M Grace Jan 2025

18 Kda Translocator Protein (Tspo) Is Upregulated In Rat Brain After Peripheral Nerve Injury And Downregulated By Diroximel Fumarate, Rafael A Cazuza, Sever M Zagrai, Anamaria R Grieco, Thomas D Avery, Andrew D Abell, Hsiao-Ying Wey, Marco L Loggia, Peter M Grace

Faculty, Staff and Student Publications

Neuroimmune signaling is a key process underlying neuropathic pain. Clinical studies have demonstrated that 18 kDa translocator protein (TSPO), a putative marker of neuroinflammation, is upregulated in discrete brain regions of patients with chronic pain. However, no preclinical studies have investigated TSPO dynamics in the brain in the context of neuropathic pain and in response to analgesic treatments. We used positron emission tomography-computed tomography (PET-CT) and [18F]-PBR06 radioligand to measure TSPO levels in the brain across time after chronic constriction injury (CCI) of the sciatic nerve in both male and female rats. Up to 10 weeks post-CCI, TSPO expression was …


Lp-118 Is A Novel B-Cell Lymphoma 2 / Extra-Large Inhibitor That Demonstrates Efficacy In Models Of Venetoclaxresistant Chronic Lymphocytic Leukemia, Janani Ravikrishnan, Daisy Y Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, Kerrya Rogers, Adam S Kittai, Seema A Bhat, Mary C Collins, Matthew S Davids, Nitin Jain, William G Wierda, Rosa Lapalombella, John C Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P Anthony, Jennifer A Woyach, Deepa Sampath Jan 2025

Lp-118 Is A Novel B-Cell Lymphoma 2 / Extra-Large Inhibitor That Demonstrates Efficacy In Models Of Venetoclaxresistant Chronic Lymphocytic Leukemia, Janani Ravikrishnan, Daisy Y Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, Kerrya Rogers, Adam S Kittai, Seema A Bhat, Mary C Collins, Matthew S Davids, Nitin Jain, William G Wierda, Rosa Lapalombella, John C Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P Anthony, Jennifer A Woyach, Deepa Sampath

Faculty, Staff and Student Publications

Patients with chronic lymphocytic leukemia (CLL) respond well to initial treatment with the B-cell lymphoma 2 (BCL2) inhibitor venetoclax. Upon relapse, they often retain sensitivity to BCL2 targeting, but durability of response remains a concern. We hypothesize that targeting both BCL2 and B-cell lymphoma-extra large (BCLXL) will be a successful strategy to treat CLL, including for patients who relapse on venetoclax. To test this hypothesis, we conducted a pre-clinical investigation of LP-118, a highly potent inhibitor of BCL2 with moderate BCLXL inhibition to minimize platelet toxicity. This study demonstrated that LP-118 induces efficient BAK activation, cytochrome C release, and apoptosis …


Strawberry Season Settles, The Crimson Nestles, Tra Huong Vo Jan 2025

Strawberry Season Settles, The Crimson Nestles, Tra Huong Vo

Student Scholarship

No abstract provided.


Zika Virus Modulates Arthropod Histone Methylation For Its Survival In Mosquito Cells, Telvin Harrell Jan 2025

Zika Virus Modulates Arthropod Histone Methylation For Its Survival In Mosquito Cells, Telvin Harrell

Biological Sciences Faculty Publications

Zika virus (ZIKV) is a mosquito-borne human pathogen that causes mild febrile illness in adults and severe neurological complications and microcephaly in newborns. Studies have reported that ZIKV modulates methylation of human and viral RNA critical for its replication in vertebrate cells. In this study, we show that ZIKV modulates mosquito S-adenosyl methionine (SAMe)-synthase, an enzyme involved in the production of SAMe (methyl donor), and histone methylation for its survival in mosquito cells. Reverse transcription quantitative PCR followed by immunoblotting analysis showed increased amounts of SAMe synthase at both RNA and protein levels, respectively, in C6/36 mosquito cells infected with …


Addressing The Productivity-Susceptibility Analysis In Data-Limited Fisheries For Understudied Fish In The Marine Aquarium Trade, Alice Wynn, Jemelyn Baldisimo, Gabrielle Baillargeon, Michael Tlusty, Andrew Rhyne Jan 2025

Addressing The Productivity-Susceptibility Analysis In Data-Limited Fisheries For Understudied Fish In The Marine Aquarium Trade, Alice Wynn, Jemelyn Baldisimo, Gabrielle Baillargeon, Michael Tlusty, Andrew Rhyne

Biological Sciences Faculty Publications

The marine aquarium trade (MAT) harvests millions of coral reef fishes from the wild yearly. While the MAT supports fishers, hobbyists and marine education, harvested fishes are crucial in maintaining coral reef health and balanced marine cycles within their native habitats. Understanding the impact of the MAT on fish populations is critical for sustaining the trade in the long-term. Productivity-susceptibility analyses (PSAs) offer semiquantitative methods of analyzing the productive capacity of each fish stock, as well as its susceptibility to overfishing. The present study revises and expands upon a PSA conducted by Baillargeon et al. (2020) that focused on 32 …


The Role Of Tgf-Beta Superfamily Members In Immune Homeostasis And Disease, Natalie Eva Nieuwenhuizen, Ioannis Eleftherianos, Piotr Jan Kraj, Maria Semitekolou Jan 2025

The Role Of Tgf-Beta Superfamily Members In Immune Homeostasis And Disease, Natalie Eva Nieuwenhuizen, Ioannis Eleftherianos, Piotr Jan Kraj, Maria Semitekolou

Biological Sciences Faculty Publications

[Introduction] The Transforming Growth Factor beta (TGF-beta) superfamily, encompassing molecules such as TGFs, activins, Bone Morphogenetic Proteins (BMPs), Growth/Differentiation Factor (GDFs) and Nodals, represents the largest family of growth and differentiation factors, playing crucial roles in developmental and physiological processes across animal species (1). These molecules are integral to tissue homeostasis and cell fate determination. Among them, TGF-beta is particularly noted for its regulatory influence on immune responses and tissue fibrosis (2, 3). Recent research has expanded our understanding of the immune functions of other superfamily members, including activin A and BMPs (4). These molecules signal through receptor complexes composed …


Squid Paralarvae Turn With High Agility Using Jets Near The Reynolds Number Threshold For Viscous Domination, Ian K. Bartol, Alissa M. Ganley, Paul S. Krueger, Joseph T. Thompson Jan 2025

Squid Paralarvae Turn With High Agility Using Jets Near The Reynolds Number Threshold For Viscous Domination, Ian K. Bartol, Alissa M. Ganley, Paul S. Krueger, Joseph T. Thompson

Biological Sciences Faculty Publications

Turning is critical for survival in the ocean, as marine animals need to maneuver to capture prey, elude predators, and navigate complex environments. While prior research has focused on turning performance of adult swimmers, less is known about early ontogenetic stages that locomote within lower Reynolds number (Re) regimes, especially young jetters. To evaluate squid paralarval turning proficiency and the role of the pulsed jet in maneuvers, recently hatched longfin squid Doryteuthis pealeii swimming in a viewing chamber were studied using digital particle image velocimetry and kinematic motion analyses. Paralarvae exhibited a wide repertoire of turning behaviors, including those performed …


Genome-Wide Snp Analyses Reveal High Gene Flow Of Endemic Smallscale Croaker (Boesemania Microlepsis) In The Lower Mekong Basin, Quyen Dang Ha Vu, Christopher E. Bird, Oanh Thi Truong, Sang Quang Tran, Ellen E. Biesack, Amanda S. Ackiss, Kent E. Carpenter, Binh Truy Dang Jan 2025

Genome-Wide Snp Analyses Reveal High Gene Flow Of Endemic Smallscale Croaker (Boesemania Microlepsis) In The Lower Mekong Basin, Quyen Dang Ha Vu, Christopher E. Bird, Oanh Thi Truong, Sang Quang Tran, Ellen E. Biesack, Amanda S. Ackiss, Kent E. Carpenter, Binh Truy Dang

Biological Sciences Faculty Publications

The Smallscale Croaker, Boesemania microlepis, is a valuable fishery resource in the Mekong River basin that lacks clear biological data to understand its basic ecology and conservation management priorities. This species is common in the southernmost floodplain of the Mekong which extends from Tonlé Sap in Cambodia to the Mekong Delta in Vietnam. This floodplain is of particular biodiversity conservation concern because of the many upstream dams that restrict water flow in an ecology that relies heavily on a flood-pulse cycle. The literature regarding the biology B. microlepis in this region contains conflicting ideas that populations are both highly …


Endocrine Responses To Two Distinct Foraging Contexts In The Bonobo (Pan Paniscus), Lauren Mitchell Jan 2025

Endocrine Responses To Two Distinct Foraging Contexts In The Bonobo (Pan Paniscus), Lauren Mitchell

Master's Theses

In gregarious animals, a social structure characterized by female dominance is relatively rare. However, bonobos (Pan paniscus), one of the two species most closely related to humans, are characterized by partial female dominance, with females forming close social bonds. In contrast, chimpanzees (Pan troglodytes), a close relative of the bonobo, are characterized by strong male-male bonding and social dominance with female chimpanzees lacking close social bonds. There is a lack of consensus concerning the reasons for these behavioral differences in Pan, specifically, the physiological processes responsible for female dominance in bonobos. The role of hormones …


Diet And Migration In The Prehistoric Populations In The Greater Nicoya Region Of Nicaragua, Ashley Nichols Whitten Jan 2025

Diet And Migration In The Prehistoric Populations In The Greater Nicoya Region Of Nicaragua, Ashley Nichols Whitten

Theses and Dissertations--Anthropology

The goal of this three-paper dissertation was to engage with the archaeological hypotheses of prehistoric migration from Mesoamerica into the Greater Nicoya Region of Nicaragua. To that aim, this dissertation contains a discussion on the current information supporting and refuting the migratory hypotheses. New data is also presented in the form of stable isotope analysis and bioarcheological analysis of dentition from prehistoric archaeological sites in Pacific Nicaragua.

The first paper titled “Prehistoric Foodways and Migration Hypotheses in the Greater Nicoya Region of Nicaragua” outlines the current available research concerning migration out of Mesoamerica into Pacific Nicaragua. The potential migration is …


A Critique Of Findings On Gun Ownership, Use, And Imagined Use From The 2021 National Firearms Survey: Response To William English, Deborah Azraek, Joseph Blocher, Philip J. Cook, David Hemenway, Matthew Miller Jan 2025

A Critique Of Findings On Gun Ownership, Use, And Imagined Use From The 2021 National Firearms Survey: Response To William English, Deborah Azraek, Joseph Blocher, Philip J. Cook, David Hemenway, Matthew Miller

Faculty Scholarship

For a paper that has not yet been through peer review or even been formally published, William English’s “2021 National Firearms Survey” has been remarkably prominent in gun rights advocacy and scholarship. As of December 2024, it has been cited in roughly sixty-five briefs, invoked at oral argument in the Supreme Court and multiple courts of appeals, and regularly cited in public writings and published academic work.

This response is offered in the spirit of a peer review. Our focus is on methodological issues, questionable statistical results, and problematic conclusions. Because of serious methodological issues, English’s draft fails to provide …