Investigation Of Lubricin-Stimulating Fda-Approved Compounds For A Disease-Modifying Osteoarthritic Drug, Swathi S. Menon

Honors Undergraduate Theses

Osteoarthritis (OA) is a degenerative disease that affects many people worldwide. Current methods of treatment are palliative, and no treatment exists to fully reverse or cure OA once it begins to progress. The discovery of a disease-modifying osteoarthritic drug (DMOAD) would increase the quality of life for millions and reduce the need for invasive procedures. Screening FDA-approved drugs ensures more promise due to their known safety profile and potential for faster translation to the clinic. The goal of this project was to conduct dose-response assays with FDA-approved drugs that have been shown to stimulate lubricin production in cells that mimic …

Development Of A Proposed Selective Medium For The Isolation And Differentiation Of P. Sordellii, Dimyana Bottros

Honors Undergraduate Theses

Clostridium, a genus of anaerobic, spore-forming bacteria, includes clinically and ecologically significant species like Clostridium difficile and Paeniclostridium sordellii. C. difficile causes antibiotic-associated colitis, while P. sordellii is linked to fatal infections and spontaneous abortions. Recent studies found both species in marine sediments, suggesting their role in environmental and wildlife health disturbances, including the 2013 mass mortality of over 300 manatees in the Indian River Lagoon. However, isolating and differentiating P. sordellii is challenging due to the lack of selective media optimized for its growth. This thesis proposes a novel selective medium tailored to P. sordellii’s physiological …

Propositional Conditioning Of Direct Religious Perception In John Wesley's Epistemology Of Salvation, Kenny Johnston

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

The San Francisco Bay Area’S Vulnerability To Sea Level Rise: Integrating Community Engagement And Equity Into Sea-Level Rise Adaptation Planning, Isabella Marie Carreon

Pomona Senior Theses

This thesis examines the San Francisco Bay Area’s vulnerability to sea-level rise (SLR), highlighting the importance of equity and community engagement in adaptation planning. The study integrates geospatial data and qualitative community input using a GIS Story Map to identify Points of Interest (POIs)—such as schools, hospitals, and public transportation routes—and assess SLR vulnerabilities across social, economic, geographic, and contamination dimensions. Case studies, such as the Regional Shoreline Adaptation Plan, demonstrate the limitations of large-scale policies in accommodating diverse communities and highlight the effectiveness of community-driven strategies. The thesis also explores innovative approaches to community engagement in educational settings and …

Plantation Matters: The Black Production Of Space In Southeastern Louisiana, 1830 To 1912, Noura Jabir

Pomona Senior Theses

Taking one Louisiana sugar plantation as a starting place, I demonstrate how African-descended laborers created life-sustaining spaces within/beyond the death-driving plantation complex during and after slavery.

From Feedlot To Floor Vote: ​​How Animal Agribusiness Wields Power To Capture The American State, Hannah Hughes

Pomona Senior Theses

This thesis examines how large-scale animal agriculture operations exercise disproportionate political influence to shape regulatory policy in their favor, often at the expense of environmental protection and public health. Through analysis of concentrated animal feeding operations (CAFOs), this study demonstrates how the animal agribusiness industry has systematically captured regulatory processes at federal, state, and local levels. The research traces industrial animal agriculture's development in the 21st century and its environmental consequences. The analysis reveals significant gaps in federal oversight, examining how the Clean Water Act and Clean Air Act have proven inadequate in regulating CAFO operations. At the state level, …

Biomechanics Of The Atherosclerotic Lipidome: (Un)Expected Statin Interactions And Membrane Remodelling, Ethan M. Fong

Pomona Senior Theses

Statins interact with lipid membranes in ways that shape their pharmacokinetics, off-target effects, and pleiotropic actions, yet these interactions' mechanical and biophysical consequences remain poorly understood. This thesis employs a combination of surface plasmon resonance (SPR), quartz crystal microbalance with dissipation monitoring (QCM-D), and rheological modelling to characterize how representative statins intercalate within biomimetic supported lipid bilayers (SLBs) of healthy and diseased composition. SPR reveals that lipophilic statins exhibit higher apparent affinities and slower dissociation kinetics, especially in cholesterol- and anionic lipid-rich membranes. QCM-D analyses demonstrate that statins alter membrane mass, dissipation, and interfacial stiffness in a statin- and membrane-dependent …

Maurice Sendak’S Trio, And What Good Picture Books Have To Say, Eli F. Protas

Pomona Senior Theses

When we teach children how to read, we start with picture books. We do this despite the fact that picture books blend visual and verbal storytelling in ways that require nuanced understandings of both elements. Rather than studying these aspects individually, a complete picture book analysis relies on examining the intersection of words and images, how they interact structurally and how each lends meaning to the other. To understand how to better close read picture books, this thesis turns to the stories of Maurice Sendak, a picture book writer and illustrator whose work redefined the relationship between words and images …

Ultra-Processed Food Intake And Dietary Intake Behaviors In Young Adults, Alexandra Black Larcom

Open Access Dissertations

Ultra-processed food (UPF) intake has been positively associated with adverse health outcomes and poor diet quality (DQ). UPFs tend to be of lower nutritional quality (NQ) than less processed foods, though NQ varies widely within each category of food processing. Young adults are the highest consumers of UPF, but UPF intake and related behaviors have not been examined in college students, a key subset of young adults. UPF overconsumption at meals has been proposed as a mechanism for the association between UPF intake, poor DQ, and adverse health outcomes, though no existing studies have considered NQ. Further, consumer understanding of …

Using An Ecological And Cultural Lens To Examine The 1st Year Persistence And Science Identity Development Of At-Risk Biology Students Experiencing Multiple Equity-Minded High Impact Practices, Aura Fajardo Grandidge

Open Access Dissertations

In this study, I used an ecological and a cultural perspective to examine the first-year experiences of two cohorts of biology students exposed to multiple equity-minded High Impact Practices (HIPs) designed to promote their persistence and science identity development.

In chapter 1, I applied Graham et al.’s Persistence Framework (2013) and Bronfenbrenner’s Ecological Systems Theory (1977) to investigate the bridges and barriers to persistence that biology students face while experiencing either an equity minded learning community, a first-year seminar, a course-based research experience, and/or an active learning introductory biology course. Using a mixed methods approach that focused on phenomenology, I …

The Chemical Ecology Of A Caribbean Boulder Coral During Restoration And The Interplay Between Fish Predation And Microbiome Variation, Catherine E. Raker

Open Access Dissertations

Coral reefs are one of the most biodiverse and productive ecosystems on the planet. In recent decades, however, climate change and other global threats have caused severe declines in live coral cover worldwide. Coral propagation, or “gardening,” is a popular strategy to attempt to restore healthy corals to degraded reefs. Slow-growing boulder corals are often restored using microfragmentation, where cutting coral colonies into roughly 1 cm² fragments can increase their growth rates up to 5x. However, extreme early mortality of fragments has been observed in the field, which has been at least partially attributed to predation. It has been …

Corridor Proximity And Habitat Influence On Small Mammal Rescue Call Frequency, Fernando Herrera

IdeaFest 2025

This project spatially analyzes mammal wildlife rescue call data in McKinleyville, Arcata, and Eureka, CA, to understand how wildlife corridors influence the location and frequency wildlife are brought in for rehabilitation.

James' Fabulous Mobile Dog Food Pantry: A Grassroots Initiative!, James Brother

IdeaFest 2025

I developed a mobile dog food pantry to meet the needs of unsheltered pets across Humboldt County. Using donations from various sources and implementing similar models used by local nonprofits, I developed access to pet food in areas with an unmet need.

How Does Restoration Affect Food Web Dynamics Within Quail Populations In The Mckinleyville Land Trust Dow’S Prairie Educational Wetland?, Taylor Shaw, Jesika Gonzalez, Lorilynn Acosta, Logan Blank, Zen Godinez, Amir Malikyar, Nanette Durbin, Nievita Bueno Watts

IdeaFest 2025

The McKinleyville Land Trust’s Dow’s Prairie Educational Wetland is a 2.55-acre endangered coastal prairie wetland in California, conserved in 2009. Restoration efforts with the Wiyot Tribe and U.S. Fish & Wildlife removed invasives and reintroduced native plants, but coincided with declining California quail (Callipepla californica) populations. This study establishes the first baseline conditions, using wildlife cameras and botanical surveys to assess quail habitat suitability, examining invasive removal, predation, and fragmentation impacts. Findings will guide adaptive management to balance biodiversity and restoration, while honoring the Baduwa’t Wiyot’s ancestral homeland.

Fawn Awareness - A Health Education Initiative, Jessica De Laguna

IdeaFest 2025

"Fawn Awareness" is a year-long health education initiative highlighting the often-overlooked fourth stress response: Fawn, or the “Submit” response. Seen across the animal kingdom, submission can be just as vital for survival as fight, flight, or freeze. In humans, Fawn often develops in childhood as a way to maintain a sense of security with inconsistent caregivers, later manifesting as difficulty setting boundaries and chronic people-pleasing. This project includes a YouTube video, news article, and research paper featuring expert insight and real-life anecdotes to raise awareness and promote mental health through understanding this misidentified trauma response.

Being A Role Model At The Morris School, Arthur Frye

IdeaFest 2025

I decided to do scientific studies on the stream flow rate as well as water depth, width, and terrace height on two separate creeks in Humboldt county. The first creek is called the Jolly Giant creek which is located directly behind Founders Hall on campus, and the second creek that I decided to do my research on is the Strawberry creek, which is located directly behind my house. I used a measuring rod and measuring tape for my measurements, as well as three distinct objects to float down the creek which was a lemon, a kiwi, and a lacrosse ball.

On Emerging Technologies: The Old Regime And The Proactivity, Ran Xi

Cardozo International & Comparative Law Review

Nowadays, emerging technologies are revolutionizing nearly every facet of human life, shaping legal, cultural, political, and technological landscapes. Despite various breakthroughs, emerging technologies have also brought to society legal and regulatory challenges, such as the pacing problem, regulatory silos, and the black box issue. However, existing state-centric regulation on emerging technologies results in fragmented, inconsistent, and ineffective statutes and policies. The traditional regulatory regime, due to its reactive mindset, incremental approaches, and tools of modest efficacy, fails to mitigate associated risks and harms, sometimes even impeding technological innovation. To tackle this dilemma, this Article proposes a proactive law approach with …

Land Grant Report 2023-2024, Tennessee. Higher Education Commission.

Land Grant Funding Report

No abstract provided.

Academic Supply And Occupational Demand Report 2025, Improving The Pipeline For Tennessee's Workforce, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.

Fluke Egg Sedimentation Test Procedure, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

The department’s approved procedure for detecting trematode eggs and the Eimeria leuckarti sedimentation method (FEST) on faecal samples.

Estimating The Carbon Footprint Of Sheep Production In Western Australia, Tafesse Estifanos, Christophe D'Abbadie, Johnny Machon, Amir Abadi Abadi Ghadim, Gus Manatsa, Paul Mattingley, Ross Kingwell, Kevin Foster

Farm Systems and Economics published reports

Western Australia’s broadacre mixed farming systems combine cropping and sheep production and are the largest component of the state’s agricultural sector. The south west Western Australia (WA) agricultural area hosts about 98% of the state's sheep flock. The sheep industry contributed $1.5 billion to the state’s economy in 2021-22 and accounts for about a quarter of on-farm greenhouse gas (GHG) emissions. Most sheep industry emissions (over 80%) come from methane produced by the sheep. Despite this environmental impact, only 9.9% of Australian sheep producers have estimated their emissions, which limits the industry's ability to monitor and manage carbon footprints effectively. …

Skeleton Weed In Western Australia: 2025 Management Guide, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity bulletins

Skeleton weed can reduce crop yields by competing for moisture and nutrients (mainly nitrogen).

This guide helps you manage and eradicate skeleton weed infestations on your property, and helps to stop the spread across WA.

Without the coordinated program aimed at controlling the spread, skeleton weed would now be much more abundant and widely established throughout cereal growing areas.

If you find skeleton weed on your property, we can help you get rid of it.

Skeleton weed is unpredictable and can spread over long distances due to wind dispersal, but once identified it can be managed effectively and eradicated

Skeleton Weed In Western Australia: Control Program 2024–2025, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity bulletins

Key program changes

Winter eradication program

New herbicide recommendations for control in crops, legume based annual pastures, plantations and glyphosate tolerant canola.

• The minimum size of ‘squares’ (infested areas) has been reduced from 40 m x 40 m (0.16 ha) to 20 m x 20 m (0.04 ha) to help reduce the winter treatment area.
• Landholders will need to consult with DPIRD/LAG officers to assess the degree of infestation before working or cultivating through squares in Code 1 paddocks.
• Clopyralid (LontrelTM) herbicide will no longer be provided for treatment on heavily infested paddocks. Landholders will still be required to undertake …

The Divine Call: Theophanies Of Athena And Yhwh In Comparative Perspective, Kenny Gomes Ebinger

Master's Theses

Problem

While parallels between Ancient Near East (ANE) literature and the Hebrew Bible are well established in contemporaneous scholarship, the Greek corpus has received little attention in recent studies. This paper addresses this gap by investigating a theophany scene from each corpus, in order to compare how the human-deity encounter is presented in Exodus 3:1–4:17 and Odyssey 1:96–324.

Method

The textual analysis of each scene employs a narratological framework. It takes both texts synchronically and grounds its comparison on the narrative formal elements, structures, and functions. The similarities and differences between each theophany are presented by their emerging themes and …

The State Of Man In Romans 7:22-25: Historical And Exegetical Approaches, J Daniel Miranda

Master's Theses

Problem

This thesis addresses the question as to the identity of “I” in Romans 7 and the related spiritual experience. Romans 7 is a very complex chapter that has elicited multiple discussions, which still do not answer the theological problems satisfactorily. Such theological pluralism has also led to various views regarding sin and salvation. Since understanding sin and redemption are fundamental to one’s salvation, there are strong feelings related to the different positions taken. This has also been the case in Adventism, and, unfortunately, this has affected the unity of the church. Part of the problem is seeing the regenerate-unregenerate …

Dopamine Hits To Data Bits: Harnessing Brain Chemistry To Drive The Next Generation Of Computing, Keller Bueneman

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Investigating Relatedness Within Breeding Units Of The Highly Social Bushtit (Psaltriparus Minimus), Fiona Skye Connelly

Theses and Dissertations--Biology

Cooperative breeding systems represent an array of varied reproductive strategies and remain a topic of interest in behavioral ecology (i.e., Riehl 2013, Cornwallis et al. 2017). Different manifestations of cooperative breeding, such as cooperative polyandry, no doubt have unique evolutionary pressures tied to local ecologies which have led to their proliferation. Of particular interest are species that show flexibility in their use of reproductive strategies, wherein individuals may choose one strategy over another given a specific circumstance. Here, I used double-digest restriction site-associated DNA sequencing (i.e., ddRAD-seq) to investigate bushtit (Psaltriparus minimus) reproductive strategies and the relatedness between …

Temporal Dynamics Of Programmed Genome Rearrangement In Sea Lamprey Embryogenesis: A Deep Learning & Lightsheet Imaging Approach To Studying Early Developmental Transitions, Kasturi Rajandran

Theses and Dissertations--Biology

Programmed genome rearrangement (PGR) in the sea lamprey (Petromyzon marinus) leads to the elimination of ~0.5Gb (20%) of the germline genome during early embryogenesis, yet its timing relative to the maternal-to-zygotic transition (MZT) remains unclear. In this study, we imaged embryos cleared at 3-hour intervals (up to 72 hours post fertilization (hpf)) using high-resolution lightsheet fluorescence microscopy and a custom deep-learning image-analysis pipeline (~80% accuracy) to quantify nuclei and micronuclei counts. Micronuclei, which are the hallmarks of PGR first appear between 24 to 27hpf (vs ~36hpf previously reported) indicating PGR starts earlier than previously reported in the sea …

The Role Of Metabolic Gate Keepers In Cell Fate Decision Making, Brian Kelly

Theses and Dissertations--Biology

Maintaining cellular energy balance and redox stability is crucial to cell survival, with glutamine metabolism playing a central role. While extensively studied in cancer, where it supports biosynthesis and reduces oxidative stress to promote tumor growth, its function in non-cancerous contexts like tissue development and muscle regeneration remains less understood. A key aspect of stem cell biology is quiescence, a metabolically dormant state that preserves the stem cell pool, yet the mechanisms regulating this state are not fully clear. Here, we identify glutamine metabolism as a critical factor governing myoblast proliferation and quiescence through a metabolic program distinct from that …

Does Time Actually Fly When You're Having Fun? A Review Of Time Perception In Differing Environments, Arthur Khayat

Scientific Kenyon: The Neuroscience Edition

No abstract provided.