Digital Commons Network^™

Comparing Vr And Tv In Nigeria And The U.S.: Impacts On Empathy, Engagement, And Enjoyment, Jinhee Yoo, Eugene A. Ohu, Radosław Mącik

Journal of International Technology and Information Management

This study (N = 170), involving participants from Nigeria and the U.S., investigated how different technologies (TV and VR) affect users' empathy (α = .93), engagement (α = .93), enjoyment (α = .93), preferences, and likelihood of technology use. Participants watched an animated documentary titled “Is Anna OK?” at two different time points, utilizing VR (Oculus Rift S) and TV, following which they completed measuring empathy, engagement, enjoyment, device preference, and usage likelihood. Analysis via one-way ANOVA and chi-square tests revealed that VR users reported significantly higher empathy and enjoyment compared to TV viewers, particularly on second viewing. Combining both …

Trace Level Identifications Of N-Ethylnicotinamide In Racing Horses Associated With A Vitamin B3 Supplement: Case Reports And Analysis, Clara Fenger, Kimberly Brewer, Abelardo Morales-Briceño, Andreas F. Lehner, George A. Maylin, Robert Holland, Levent Dirikolu, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Nikethamide, N,N-diethyl-3-pyridinecarboxamide (Coramine®) is a central nervous system stimulant at one time used therapeutically in human medicine but no longer marketed in the US. Nikethamide is classified a Drug Class 1, Penalty Class A substance by the Association of Racing Commissioners International (ARCI) and as a Horseracing Integrity and Safety Authority (HISA) SO or banned Stimulant that lacks FDA approval. Identifications of Nikethamide or its metabolite N-Ethylnicotinamide in racing samples can result in significant penalties in horse racing. Nikethamide is rapidly metabolized to N-Ethylnicotinamide, which remains detectable in plasma and urine leading to its use as a regulatory “marker” of …

Host Defense Inside & Outside Of The Immune System: Modeling Antimicrobial Immunity By Gbps, Zhongyu Yuan

Yale Graduate School of Arts and Sciences Dissertations

Traditional views of host defense often focus on antibody-mediated neutralization, cytotoxic T-cell plus NK-cell-mediated killing, and phagocytic activities by cell populations originating in the bone marrow as part of the classical immune system. Additional effector activities, however, also operate in non-immune cells which compose the stroma or parenchyma of host tissues. These latter cell populations often mobilize antimicrobial activities in response to cytokines such as type II IFN (IFN-gamma; IFN-) against a wide variety of intracellular pathogens.

Among the most prominent IFN--stimulated genes are a family of immune dynamin-like GTPases termed the Guanylate Binding Proteins (GBPs). GBPs are widely expressed …

Characterization Of Litigation After Tympanoplasty And Mastoidectomy In The United States, Alyssa D. Reese, Lauren A. Dinardo, Soumya Gupta, Kristina F. Powers, Samuel Colca, Michele M. Carr

Department of Otolaryngology (ENT) Faculty Publications

Introduction

Tympanoplasty and mastoidectomy are common procedures performed by otolaryngologists that can result in complications for which patients may seek compensation. Medical malpractice case analyses may offer insight into how clinicians can avoid risk and improve patient satisfaction. We aimed to comprehensively characterize litigation after mastoidectomies and tympanoplasties in the United States.

Methods

The Westlaw Campus Research legal database was searched for all available court decisions associated with claims of medical malpractice after tympanoplasty and/or mastoidectomy in the United States between 1975 and 2022. Information on the plaintiffs' relationships to the patients, patient characteristics, states where the procedures took place, …

A Comparison Of Allergen Sensitization Profiles In Patients With Chronic Rhinosinusitis With And Without Nasal Polyposis, Lauren Trzcinski, Suhas Bharadwaj, Randall A. Bloch, Joseph K. Han, Kent K. Lam

Department of Otolaryngology (ENT) Faculty Publications

Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are common comorbid sinonasal conditions. CRS is classically divided into two distinct phenotypes: CRS with nasal polyposis (CRSwNP) and CRS without nasal polyposis (CRSsNP). The purpose of this retrospective observational study is to determine whether aeroallergen sensitization profiles in patients with comorbid CRS and AR can distinguish between CRSwNP and CRSsNP. A total of 241 patients diagnosed with comorbid CRS and AR who underwent skin prick testing or in vitro allergy testing in a single tertiary rhinology practice were included for evaluation. The rates of allergen-specific sensitizations in CRSwNP patients were compared with …

Sensor Fusion For Enhancing Motion Capture : Integrating Optical And Inertial Motion Capture Systems, Hailey Hicks

Theses

This study aimed to create and evaluate a custom sensor fusion algorithm based on Gauss-Newton optimization that combines Optical Motion Capture (OMC) and Inertial Motion Capture (IMC) measurements to combat the limitations of solely using each system. The goal was to demonstrate how inertial measurement unit (IMU) data can be seamlessly integrated into motion capture data to provide a more efficient and reliable gap filling process for future research. The algorithm takes the first and last frame of OMC data, as quaternions, and fills the rest with IMU gyroscope orientation data to simulate gaps of up to ten minutes. The …

Factors Affecting Freshwater Fish Communities In Two North Alabama Counties, Joshua Fitts

Theses

This study examined how physical habitat characteristics influence freshwater fish diversity in streams of Madison and Limestone Counties, Alabama. Ten 150-meter stream reaches were sampled using backpack electrofishing and seining, with habitat variables measured at fixed transects. Principal component analysis identified four main habitat gradients representing flow and substrate, channel size, gravel dominance, and canopy–bedrock conditions. Although overall species richness and Shannon diversity were not significantly related to these gradients, species-specific correlations revealed clear ecological preferences. Regression models showed that root wads, herbaceous vegetation, and riprap modestly increased richness, emphasizing the role of structural diversity. These findings highlight the importance …

Schroeder V. Oak Grove Farm Homeowners Association, North Carolina Supreme Court

Historical and Topical Legal Documents

No abstract provided.

A Culture-Centered Approach To Exploring The Impact Of Culturallyappropriate Communication On Patient-Provider Communication Satisfaction For Blackfeet Patients With Type 2 Diabetes, Zita K. Ottersbach

Graduate Student Theses, Dissertations, & Professional Papers

This study explores how culturally appropriate communication influences perceived quality of care and communication satisfaction among patients with T2D. Grounded in the Culture-Centered Approach (Dutta, 2008), this study explores how cultural identity, systemic structures, and communication practices shape the ways that Amskapi Pikuni individuals navigate their care, and seeks to ask: How, if at all, does a provider’s culturally competent communication influence a Blackfeet patient’s management of their T2 Diabetes? This project is based on in-depth, qualitative interviews with 13 Blackfeet participants, most living within the exterior boundaries of the Blackfeet reservation and receiving their primary healthcare at the local …

Education About, In, And For Wetlands: Practices, Premises, Possibilities, And Challenges, Tom Marcinkowski

Mathematics and System Engineering Faculty Publications

The purpose of this paper is to review areas of educational theory, research, and practice relevant to wetlands education, notably education about, in, and for wetlands. Five key areas are reviewed: (a) from the Report of the Intergovernmental Conference on Environmental Education, goals and objectives for wetlands education; (b) from the literature, major curricular and instructional approaches in and elements of wetlands education; (c) from the literature, broad instructional strategies available to and commonly used in wetlands education; (d) from websites of federal agencies in the U.S., education, outreach, and training programs that focus on education about, in, and for …

Ground-Based Cloud Type Classification For Aviation Weather Hazard Detection Using Deep Learning, Marcus P. Cote, Michael E. Splitt, Steven M. Lazarus, Ryan T. White, Cecilia G. Baker

Mathematics and System Engineering Faculty Publications

General aviation pilots who encounter hazardous weather face a heightened risk of fatal accidents compared to those in other sectors of aviation. To help avoid unplanned weather encounters, accurate information on cloud type and sky conditions can enhance situational awareness and hazard recognition. Among available weather information resources, ground-based webcam networks are growing for aviation meteorology and other interests such as wildfire monitoring. These webcams can provide near-real-time visual weather information to pilots, especially in regions of complex terrain where traditional weather observation methods may lack adequate spatial and temporal coverage. To harness the benefits from webcams while reducing the …

Defining An Irrelevant Plasma Concentration For Trichlormethiazide In Racing Horses – A Case Report And Analysis, Kimberly Brewer, Justin C. Holmes, Clara Fenger, Abelardo Morales-Briceño, Andreas F. Lehner, George A. Maylin, Robert Holland, Levent Dirikolu, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

This communication reviews the matter of the clinical, pharmacological, and regulatory significance of a 4.95 nanogram/ml identification of trichlormethiazide in urine from a horse six days after administration of a compounded trichlormethiazide/ dexamethasone preparation. This combination of dexamethasone and trichlormethiazide has historically been widely used in bovine and equine medicine to reduce local inflammation and edema. The horse was administered an oral formulation of trichlormethiazide 400 mg /dexamethasone 10 mg per packet under veterinary supervision on days 7 and 6 before the race in question. Following the race, the post-race urine sample from the horse tested “positive” for trichlormethiazide at …

Trace Level Identifications Of N-Ethylnicotinamide In Racing Horses Associated With A Vitamin B3 Supplement: Case Reports And Analysis, Clara Fenger, Kimberly Brewer, Abelardo Morales-Briceño, Andreas F. Lehner, George A. Maylin, Robert Holland, Levent Dirikolu, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Nikethamide, N,N-diethyl-3-pyridinecarboxamide (Coramine®) is a central nervous system stimulant at one time used therapeutically in human medicine but no longer marketed in the US. Nikethamide is classified a Drug Class 1, Penalty Class A substance by the Association of Racing Commissioners International (ARCI) and as a Horseracing Integrity and Safety Authority (HISA) SO or banned Stimulant that lacks FDA approval. Identifications of Nikethamide or its metabolite N-Ethylnicotinamide in racing samples can result in significant penalties in horse racing. Nikethamide is rapidly metabolized to N-Ethylnicotinamide, which remains detectable in plasma and urine leading to its use as a regulatory “marker” of …

What Shapes Environmental Identity: Insights From Highly Environmentally Literate Students, Marušić-Jablanović Milica, Zorica Stanišić, Jelena Stanišić, Dragana Gundogan, Tom Marcinkowski

Mathematics and System Engineering Faculty Publications

The paper aimed to describe features of the environmental identity of primary school students (age 13-14) in Serbia, as well as the experiences they find most influential in shaping their environmental identity. Specifically, students from the two best-performing classes (N=34), based on their scores on environmental literacy assessment responded to an open-ended questionnaire regarding their relationship with nature and the most important experiences shaping this relationship, in both private and school contexts. The students offered evidence of features of their environmental identity in terms of: environmental affect-sensitivity, environmental concern, moral reasoning, as well as pro-environmental behavior as its correlate. Both …

Combination Of Hsp90 Inhibitors And Hsp70 Inducers Prevent Hydrochloric Acid-Induced Pulmonary Fibrosis In Rabbits, Ruben M. L. Colunga Biancatelli, Pavel A. Solopov, Tierney Day, Dan E. Austin Jr., Len E. Murray, John D. Catravas

Bioelectrics Publications

Combined therapies with Heat Shock Protein 90 (HSP90) inhibitors and Heat Shock Protein 70 (HSP70) inducers are gaining significant interest in cancer and cardiovascular research. Here, we tested the hypothesis that HSP90 inhibitors and HSP70 inducers, together, can block the development of pulmonary fibrosis. We exposed New Zealand White Rabbits to hydrochloric acid (HCl, 0.1 N, 1.5 mL/kg), one of the top five chemicals most commonly involved in accidental exposures and inhalation injuries worldwide, and treated animals with either the orally available HSP90 inhibitor TAS-116 (1.7 mg/kg 5x/week) or TAS-116 combined with the HSP70 inducer, geranylgeranyl acetone (GGA, 50 mg/kg, …

Potentiation Of Gelonin Cytotoxicity By Pulsed Electric Fields, Olga N. Pakhomova, Eleni Zivla, Giedre Silkuniene, Mantas Silkunas, Andrei G. Pakhomov

Bioelectrics Publications

Gelonin is a ribosome-inactivating protein with extreme intracellular toxicity but poor permeation into cells. Targeted disruption of cell membranes to facilitate gelonin entry is explored for cancer and tissue ablation. We demonstrate a hundreds- to thousands-fold enhancement of gelonin cytotoxicity by pulsed electric fields in the T24, U-87, and CT26 cell lines. The effective gelonin concentration to kill 50% of cells (EC₅₀) after electroporation ranged from <1 nM to about 100 nM. For intact cells, the EC₅₀ was unattainable even at the highest gelonin concentration of 1000 nM, which reduced cell survival by only 5–15%. For isoeffective electroporation treatments using 300 ns, 9 µs, and 100 µs pulses, longer pulses were more efficient at lowering gelonin EC₅₀. Increasing the electric field strength of 8, 100 µs pulses from 0.65 to 1.25 kV/cm reduced gelonin EC₅₀ from 128 nM to 0.72 nM. Conversely, the presence of 100 nM gelonin enabled a more than 20-fold reduction in the number of pulses required for equivalent cell killing. Pulsed electric field-mediated delivery of gelonin shows promise for hyperplasia ablation at concentrations sufficiently low to minimize or avoid systemic toxicity.

The Ptp4a3 Inhibitor Kvx-053 Reduces Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Virulence, Inflammation, And Development Of Acute Lung Injury In K18-Hace2 Mice, Ruben M. L. Colunga-Biancatelli, Pavel A. Solopov, Caitlin M. Woodson, Irving Coy Allen, Ivan Akhrymuk, Maryna Akhrymuk, Brittany N. Heath, Hannah M. Ivester, Tierney Day, Dan E. Austin, Kylene Kehn-Hall, John S. Lazo, Elizabeth R. Sharlow, John D. Catravas

Bioelectrics Publications

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused a global health crisis, marked by high transmissibility and virulence. Despite widespread vaccination efforts, effective treatments for COVID-19, particularly for severe cases leading to Acute Respiratory Distress Syndrome (ARDS), remain limited. This study investigates the efficacy of KVX-053, a protein tyrosine phosphatase type IVA (PTP4A3) small molecule inhibitor, in modulating SARS-CoV-2-induced inflammation and lung injury using in vitro cell models and in vivo K18-hACE2 transgenic mice. KVX-053 reduced in vitro pro-inflammatory cytokine expression, including TNFα, CXCL10, and CXCL11, without impacting viral replication or cell viability. K18-hACE2 mice treated with KVX-053 demonstrated …

Place-Based Learning Practices: A Diptych Case Study Of Human And More-Than-Human Relationality At The Tribal And Western Academic Institutional Interface, Karley M. Rojas-Vienneau

Cal Poly Humboldt theses and projects

The ‘Place-Based Learning Practices Project’ is a graduate project under the Native American Studies Department Rou Dalagurr Food Sovereignty Lab and Traditional Ecological Knowledges Institute (FSL). Making contributions at the intersection of Western academia and Indigenous science, it imagines and realizes content, policies, and protocols surrounding two case studies and the larger cal poly humboldt (cph) institution which respect, honor, and uplift Indigenous sovereignty and resurgence in partnership with the Blue Lake Rancheria Tribe and the greater regional tribal community. Encompassing two projects internal and external to the institution, I aim to address the construction of controlled and protective environments …

Jaguar (Panthera Onca) Population Status And Conservation Needs In Panama Revealed Using Spatial Density And Occupancy Models., Rebeca E. Becdach

Cal Poly Humboldt theses and projects

Jaguars (Panthera onca) are key predators and the largest felid in the Americas. The species is listed as near threatened globally due to habitat loss, fragmentation, and human persecution. Their population decline can negatively affect the structure and functioning of the ecosystems they inhabit. Conservation efforts for jaguars and their habitat require understanding jaguar populations and how they are impacted by human presence across their range. This information is lacking in Panama, a critical portion of the Jaguar range. Panama forms a narrow land bridge connecting Central and South America, integral to wildlife movement, including jaguars, across both …

Anabolic Properties Of The Progestin Altrenogest And Its Regulation As An Environmental Substance In Horse Racing – Review And Analysis, Andreas F. Lehner, Levent Dirikolu, Sarah Jacob, Kimberly Brewer, Abelardo Morales Briceñoe, Robert Holland, George Maylin, Clara Fenger, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Altrenogest is a progestogen substance used in equine medicine for the synchronization of ovulation during the spring breeding season and the control of estrus in mares. It accomplishes its actions by down-regulation of endometrial progesterone receptors and repression of estrogen receptor transcriptional activation. However, various groups have also measured androgen receptor binding activity for altrenogest in vitro; these findings combined with androgenic and anabolic properties roughly 1/20 in potency of testosterone and its structural similarity to the anabolic steroid trenbolone have created concerns among racing authorities of altrenogest’s potential abilities to alter the outcome of equine athletic performance, even though …

State Constitutional Development And The Criminal Procedure Revolution, Quinn Yeargain

Georgia Law Review

Questions about which rights, liberties, and guarantees are included in the U.S. Constitution’s protections, and how they are protected, have long produced animated debate among scholars, judges, and advocates. Yet, while today’s debates may seem familiar, they take place at a perilous time in our country’s trajectory. We are six decades removed from the Warren Court’s criminal procedure revolution, and just a few years into the Roberts Court’s full-throated embrace of originalist jurisprudence. Whether many of the protections we have come to know and recognize from the Warren Court—the exclusionary rule, Miranda warnings, and Gideon’s mandate—are subjected to re-evaluation …

Csbs Statements, V26, 2025, University Of Northern Iowa. College Of Social And Behavioral Sciences.

CSBS Statements

Contents:

From the Dean --- 3
Shaping Tomorrow --- 4
Helping Students Cross the Finish Line --- 10
Beyond the Uniform --- 12
Finding the Right Fit --- 14
From Patient to Colleague --- 16
Diplomacy in Action --- 18
College News --- 20
Panther Spotlights --- 24
Annual Giving --- 26
Class Notes --- 39

Loss Of Lgl1 Increases Expression Of C-Jun And Dcx In The Svz And Rms Of The Mouse Brain, Madison Leigh Gutierrez

Cal Poly Humboldt theses and projects

Glioblastoma (GBM), the most aggressive and treatment-resistant subtype of glioma, accounts for the majority of brain tumor–related mortality. A defining feature of GBM is its ability to invade healthy brain tissue through extensive cell migration, which severely limits the effectiveness of surgical and pharmacological treatments. Increasing evidence suggests that GBM cells activate gene programs known to drive normal neural stem and progenitor cell (NSPC) migration; however, the precise molecular mechanisms shared between NSPCs and GBM cells remain poorly understood. Lethal (2) giant larvae 1 (Lgl1), a conserved cortical cytoskeletal protein, has emerged as a key regulator of polarity and migration. …

Human Perception Of Ai Capabilities At Classifying Perturbed Roadway Signs, Katherine R. Garcia, Jing Chen, Yanru Xiao, Scott Mishler, Cong Wang, Bin Hu

Psychology Faculty Publications

Artificial Intelligence (AI) is crucial to numerous functions required for driving automation systems, including the computer vision techniques used to detect the roadway environment and make real-time decisions. However, the images used as inputs to the AI system may be maliciously perturbed, or manipulated, causing the AI system to make an incorrect classification. In this study, we examined humans’ perception of the AI’s computer vision capability of classifying various road sign images, including the original images, images with two different types of malicious attacks, and images that are scrambled randomly at the pixel level. Our results showed that participants rated …

Full Issue

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

No abstract provided.

Second Shift, Eve, Nick Fife

Inscape

Nick Fife is a Deaf Studies major at UVU. They feel too much too often, so they sometimes dance it out or try to put it all on paper. Nick has a particular fondness for science fiction and calico and gray tabby cats (though a bowl of Thai curry is always welcome).

Full Issue, Cinthya Ammerman Muñoz, Paul Michael L. Atienza

Humboldt Journal of Social Relations

Full issue of Humboldt Journal of Social Relations Volume 47, Place-Based Digital Inquiry

Cint Summer Lecture Series: Investigational Devices, Abby Keeley

Human Research Protection Program (HRPP) Education

No abstract provided.

The Failures Of The Biologics Price Competition And Innovation Act, Nick Corwin

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

2025-2035 Piscataqua Region Comprehensive Conservation And Management Plan, Piscataqua Region Estuaries Partnership (Prep)

PREP Reports & Publications

No abstract provided.