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Articles 29671 - 29700 of 732926

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Predicting The Suitable Habitats Of Alosimus Marginicollis (Haag-Rutenberg, 1880) (Coleoptera: Meloidae) And Evaluating Its Potential Distribution In Relation To Geographical And Climatic Barriers, Muhammed Ari̇f Demi̇r, Mahmut Kabalak Mar 2025

Predicting The Suitable Habitats Of Alosimus Marginicollis (Haag-Rutenberg, 1880) (Coleoptera: Meloidae) And Evaluating Its Potential Distribution In Relation To Geographical And Climatic Barriers, Muhammed Ari̇f Demi̇r, Mahmut Kabalak

Turkish Journal of Zoology

The main objective of this study was to predict the ecological requirements of Alosimus marginicollis (Haag-Rutenberg, 1880), for which limited ecological information is available, and to predict possible suitable habitats under current conditions and different future scenarios. An ensemble model-based approach, combining multiple algorithms (GAM, GLM, MARS, MaxEnt), was used to predict suitable habitats for this species using bioclimatic, topographic and land cover variables. The models indicated that the elevation variable among the topography variables, BIO15 (precipitation seasonality) and BIO4 (temperature seasonality) among the bioclimatic variables, and the cropland variable (cultivated and managed vegetation cover) among the land cover variables …

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Morphological, Linear, And Geometric Morphometric Differences (Skull, Mandible, And Pelvis) Among Subspecies Of Talpa Levantis (Eulipotyphla: Talpidae) With Molecular Divergence (Mtdna And Nuclear Dna), Ahmet Yesari̇ Selçuk, Alaetti̇n Kaya, Haluk Kefeli̇oğlu Mar 2025

Morphological, Linear, And Geometric Morphometric Differences (Skull, Mandible, And Pelvis) Among Subspecies Of Talpa Levantis (Eulipotyphla: Talpidae) With Molecular Divergence (Mtdna And Nuclear Dna), Ahmet Yesari̇ Selçuk, Alaetti̇n Kaya, Haluk Kefeli̇oğlu

Turkish Journal of Zoology

In this study, we conducted comprehensive analysis to determine the morphological, linear morphometric, and geometric morphometric differences between three subspecies of Talpa levantis: T. levantis levantis, T. levantis dogramacii, and T. levantis transcaucasica. Molecular analyses including mitochondrial DNA (complete cyt b gene) and nuclear DNA (BRCA-2) were also used. The subspecies of T. levantis showed similarities in the parastyle of the first upper molar and the mesostyle of the second and third upper molars, as well as in the morphology of the pelvis and linear measurements of the ventral skull, mandible, and pelvis. T. levantis dogramacii and T. levantis levantis …

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Sk8er Skull, David Norton Mar 2025

Sk8er Skull, David Norton

College of Computing and Digital Media Dissertations

Sk8r Skull is a single player video game where players must traverse the environment as a skull on a skateboard, in an effort to defeat the wizard who has stolen the rest of the skull’s body. Players must move, destroy, and grind their way through the level in order to reach the wizard. By traversing the area, players will learn the mechanics of the game, as well as some of the in-game world’s backstory. The production of Sk8r Skull was driven by examining game feel, and the “flow” state.

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Icos-Expressing Car-T Cells Mediate Durable Eradication Of Triple-Negative Breast Cancer And Metastasis, Shelley Herbrich, Mehdi Chaib, Padmanee Sharma Mar 2025

Icos-Expressing Car-T Cells Mediate Durable Eradication Of Triple-Negative Breast Cancer And Metastasis, Shelley Herbrich, Mehdi Chaib, Padmanee Sharma

Faculty, Staff and Student Publications

Triple-negative breast cancer (TNBC) remains one of the most aggressive and therapeutically challenging breast cancer subtypes. In their recent study, Cao et al introduced a B7H3-specific chimeric antigen receptor (CAR)-T cell with constitutive inducible co-stimulator (ICOS) expression (ICOS-B7H3-CAR-T), which demonstrated eradication of TNBC, including metastases, in preclinical models. These CAR-T cells exploit the expression of ICOS ligand on TNBC cells, enhancing antitumor cytotoxicity through ICOS signaling. Compared with conventional B7H3-CAR-T cells, the ICOS-B7H3-CAR-T cells exhibited superior antitumor efficacy, increased cytokine secretion, and prolonged survival in xenograft murine models. This study highlights ICOS as a promising co-stimulatory molecule for improving CAR-T …

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Spartan Daily, March 18, 2025, San Jose State University, School Of Journalism And Mass Communications Mar 2025

Spartan Daily, March 18, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 164, Issue 23

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Near-Infrared Fluorescence Imaging With An Met-Targeting Probe For Biopsy Site Selection In Patients With Oral Potentially Malignant Disorders, Jingbo Wang, Xuemin Shen, Qifan Ma, Lin Yang, Xiaoyu Zhou, Luting Wang, Junqi Cui, Chunye Zhang, Guojun Li, Neil Gross, Siyi Li, Ruimin Huang, Changyou Zhan, Zhen Cheng, Kun Wang, Jie Tian, Ying Yuan, Xiaofeng Tao Mar 2025

Near-Infrared Fluorescence Imaging With An Met-Targeting Probe For Biopsy Site Selection In Patients With Oral Potentially Malignant Disorders, Jingbo Wang, Xuemin Shen, Qifan Ma, Lin Yang, Xiaoyu Zhou, Luting Wang, Junqi Cui, Chunye Zhang, Guojun Li, Neil Gross, Siyi Li, Ruimin Huang, Changyou Zhan, Zhen Cheng, Kun Wang, Jie Tian, Ying Yuan, Xiaofeng Tao

Faculty, Staff and Student Publications

Accurate detection of malignant transformation in oral potentially malignant disorders (OPMDs) is crucial for guiding effective treatment and improving patient management. This study evaluates the potential of MET-binding peptide-indocyanine green (cMBP-ICG), a mesenchymal-epithelial transition factor (MET)-targeted near-infrared fluorescence imaging (NIRFI) probe, for biopsy site selection in OPMDs. Preclinical results demonstrate the superior accuracy of NIRFI-assisted biopsy over conventional oral examination (COE)-based biopsy in detecting high-grade dysplasia (HGD) or squamous cell carcinoma (SCC) and reducing missed detection rates. In a clinical trial with 50 patients, NIRFI-assisted biopsy achieves significantly higher diagnostic accuracy compared to COE-based biopsy (91% vs. 72%, p = …

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Did Raja Asterias Ever Occur In The Sea Of Marmara Or Were Previous Records Just Cases Of Misidentified Raja Clavata?, Hakan Kabasakal, Uğur Uzer, Fi̇rdes Saadet Karakulak Mar 2025

Did Raja Asterias Ever Occur In The Sea Of Marmara Or Were Previous Records Just Cases Of Misidentified Raja Clavata?, Hakan Kabasakal, Uğur Uzer, Fi̇rdes Saadet Karakulak

Turkish Journal of Zoology

The current inventories of elasmobranchs in the Sea of Marmara have some taxonomic problems that need to be solved. One problematic species in the elasmobranch fauna of the region is Raja clavata Linnaeus, 1758, and atypically coloured specimens of this skate species may have been misidentified in the past as congeners or closely related species. The present results show that R. asterias may be a misidentified species of the family Rajidae due to confusion with the atypically coloured R. clavata. As taxonomy is central to the integration of data sources in the context of biodiversity research and management of any …

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Using Thermal Camera Drones In Beef Cattle Roundup, Justin Wyatt Clawson, Eric Galloway, Shalyn Drake, Shawn Barstow, Ross Israelsen, Michael Pate Mar 2025

Using Thermal Camera Drones In Beef Cattle Roundup, Justin Wyatt Clawson, Eric Galloway, Shalyn Drake, Shawn Barstow, Ross Israelsen, Michael Pate

All Current Publications

Using drones with thermal sensors can be an effective tool in finding and collecting livestock from summer mountain ranges in the West. Drones can complete searches in much less time than required on horseback in demonstrated areas. Using drones reduces the workload of the rider and horse, saving time and energy and reducing the risk of injury. With proper training and certification, livestock producers can use drones to locate cattle and perform many other cost-cutting operations.

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Guanine Nucleotide Biosynthesis Blockade Impairs Mll Complex Formation And Sensitizes Leukemias To Menin Inhibition, Xiangguo Shi, Minhua Li, Zian Liu, Jonathan Tiessen, Yuan Li, Jing Zhou, Yudan Zhu, Swetha Mahesula, Qing Ding, Lin Tan, Mengdie Feng, Yuki Kageyama, Yusuke Hara, Jacob J Tao, Xuan Luo, Kathryn A Patras, Philip L Lorenzi, Suming Huang, Alexandra M Stevens, Koichi Takahashi, Ghayas C Issa, Md Abul Hassan Samee, Michalis Agathocleous, Daisuke Nakada Mar 2025

Guanine Nucleotide Biosynthesis Blockade Impairs Mll Complex Formation And Sensitizes Leukemias To Menin Inhibition, Xiangguo Shi, Minhua Li, Zian Liu, Jonathan Tiessen, Yuan Li, Jing Zhou, Yudan Zhu, Swetha Mahesula, Qing Ding, Lin Tan, Mengdie Feng, Yuki Kageyama, Yusuke Hara, Jacob J Tao, Xuan Luo, Kathryn A Patras, Philip L Lorenzi, Suming Huang, Alexandra M Stevens, Koichi Takahashi, Ghayas C Issa, Md Abul Hassan Samee, Michalis Agathocleous, Daisuke Nakada

Faculty, Staff and Student Publications

Targeting the dependency of MLL-rearranged (MLLr) leukemias on menin with small molecule inhibitors has opened new therapeutic strategies for these poor-prognosis diseases. However, the rapid development of menin inhibitor resistance calls for combinatory strategies to improve responses and prevent resistance. Here we show that leukemia stem cells (LSCs) of MLLr acute myeloid leukemia (AML) exhibit enhanced guanine nucleotide biosynthesis, the inhibition of which leads to myeloid differentiation and sensitization to menin inhibitors. Mechanistically, targeting inosine monophosphate dehydrogenase 2 (IMPDH2) reduces guanine nucleotides and rRNA transcription, leading to reduced protein expression of LEDGF and menin. Consequently, the formation and chromatin binding …

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The Autophagy Protein Atg14 Safeguards Against Unscheduled Pyroptosis Activation To Enable Embryo Transport During Early Pregnancy, Pooja Popli, Arin K Oestreich, Vineet K Maurya, Marina N Rowen, Yong Zhang, Michael J Holtzman, Ramya Masand, John P Lydon, Shizuo Akira, Kelle Moley, Ramakrishna Kommagani Mar 2025

The Autophagy Protein Atg14 Safeguards Against Unscheduled Pyroptosis Activation To Enable Embryo Transport During Early Pregnancy, Pooja Popli, Arin K Oestreich, Vineet K Maurya, Marina N Rowen, Yong Zhang, Michael J Holtzman, Ramya Masand, John P Lydon, Shizuo Akira, Kelle Moley, Ramakrishna Kommagani

Faculty, Staff and Students Publications

Recurrent pregnancy loss, characterized by two or more failed clinical pregnancies, poses a significant challenge to reproductive health. In addition to embryo quality and endometrial function, proper oviduct function is also essential for successful pregnancy establishment. Therefore, structural abnormalities or inflammation resulting from infection in the oviduct may impede the transport of embryos to the endometrium, thereby increasing the risk of miscarriage. However, our understanding of the biological processes that preserve the oviductal cellular structure and functional integrity is limited. Here, we report that autophagy-related protein ATG14 plays a crucial role in maintaining the cellular integrity of the oviduct by …

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Hatching And Caring For Chicks, Cory Farnsworth, Jacob Hadfield, Ashley Longmore Mar 2025

Hatching And Caring For Chicks, Cory Farnsworth, Jacob Hadfield, Ashley Longmore

All Current Publications

There are many reasons people are interested in raising birds. Most people who desire to start are interested in saving money and becoming more self-sufficient. Many people find excitement in hatching eggs and raising chicks. This fact sheet will help you get started with hatching eggs and raising chicks.

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Best Practices For Imaging Of Transcatheter Valve Failure: An Update From The Heart Valve Collaboratory, Omar K Khalique, Syed Zaid, Gilbert H L Tang, Mohamed Abdel-Wahab, Miriama Akodad, Vinayak N Bapat, Jeroen J Bax, Daniel J Blackman, Philipp Blanke, Sabine Bleiziffer, Davide Capodanno, Joao L Cavalcante, Lakshmi P Dasi, Ole De Backer, Matthiew De Beuel, Alison Duncan, Marc R Dweck, Miho Fukui, Aakriti Gupta, Kentaro Hayashida, Howard C Herrmann, Tsuyoshi Kaneko, Nicole Karam, Jaffar M Khan, Jan Kovac, Uri Landes, Jonathon A Leipsic, Martin B Leon, Michael J Mack, Mahesh V Madhavan, Moody M Makar, Raj R Makkar, Mouaz Al Mallah, David Meier, Thomas Modine, Atsushi Okada, Roosha K Parikh, Radoslaw Parma, Dhairya Patel, Philippe Pibarot, Bernard Prendergast, Nishath Quader, Michael J Reardon, Toby Rogers, Lucy M Safi, Stephanie L Sellers, Sabah Skaf, Giuseppe Tarantini, Didier Tchetche, Nicolas Van Mieghem, Dee Dee Wang, John G Webb, Stephan Windecker, Steven J Yakubov, Victoria Delgado, Rebecca T Hahn, Hasan Jilaihawi Mar 2025

Best Practices For Imaging Of Transcatheter Valve Failure: An Update From The Heart Valve Collaboratory, Omar K Khalique, Syed Zaid, Gilbert H L Tang, Mohamed Abdel-Wahab, Miriama Akodad, Vinayak N Bapat, Jeroen J Bax, Daniel J Blackman, Philipp Blanke, Sabine Bleiziffer, Davide Capodanno, Joao L Cavalcante, Lakshmi P Dasi, Ole De Backer, Matthiew De Beuel, Alison Duncan, Marc R Dweck, Miho Fukui, Aakriti Gupta, Kentaro Hayashida, Howard C Herrmann, Tsuyoshi Kaneko, Nicole Karam, Jaffar M Khan, Jan Kovac, Uri Landes, Jonathon A Leipsic, Martin B Leon, Michael J Mack, Mahesh V Madhavan, Moody M Makar, Raj R Makkar, Mouaz Al Mallah, David Meier, Thomas Modine, Atsushi Okada, Roosha K Parikh, Radoslaw Parma, Dhairya Patel, Philippe Pibarot, Bernard Prendergast, Nishath Quader, Michael J Reardon, Toby Rogers, Lucy M Safi, Stephanie L Sellers, Sabah Skaf, Giuseppe Tarantini, Didier Tchetche, Nicolas Van Mieghem, Dee Dee Wang, John G Webb, Stephan Windecker, Steven J Yakubov, Victoria Delgado, Rebecca T Hahn, Hasan Jilaihawi

Faculty, Staff and Students Publications

This updated Heart Valve Collaboratory framework addresses the growing concern for transcatheter valve failure (TVF) following transcatheter aortic valve replacement (TAVR). With the increasing volume of redo-TAV and surgical TAV explantation, there is a critical need for standardized pathways and protocols for evaluating TVF using echocardiography and cardiac computed tomography (CT) angiography. This document clarifies prior definitions of bioprosthetic valve deterioration and bioprosthetic valve failure in a practical, imaging directed context for TAVR. It discusses various imaging modalities for diagnosing TVF, including echocardiography, cardiac CT angiography, cardiac magnetic resonance, and positron emission tomography/CT. Recommendations are provided on the systematic imaging …

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The Autophagy Protein Atg14 Safeguards Against Unscheduled Pyroptosis Activation To Enable Embryo Transport During Early Pregnancy, Pooja Popli, Arin K Oestreich, Vineet K Maurya, Marina N Rowen, Yong Zhang, Michael J Holtzman, Ramya Masand, John P Lydon, Shizuo Akira, Kelle Moley, Ramakrishna Kommagani Mar 2025

The Autophagy Protein Atg14 Safeguards Against Unscheduled Pyroptosis Activation To Enable Embryo Transport During Early Pregnancy, Pooja Popli, Arin K Oestreich, Vineet K Maurya, Marina N Rowen, Yong Zhang, Michael J Holtzman, Ramya Masand, John P Lydon, Shizuo Akira, Kelle Moley, Ramakrishna Kommagani

2020-Current year OA Pubs

Recurrent pregnancy loss, characterized by two or more failed clinical pregnancies, poses a significant challenge to reproductive health. In addition to embryo quality and endometrial function, proper oviduct function is also essential for successful pregnancy establishment. Therefore, structural abnormalities or inflammation resulting from infection in the oviduct may impede the transport of embryos to the endometrium, thereby increasing the risk of miscarriage. However, our understanding of the biological processes that preserve the oviductal cellular structure and functional integrity is limited. Here, we report that autophagy-related protein ATG14 plays a crucial role in maintaining the cellular integrity of the oviduct by …

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Dried Blood Spots To Assess Cardiovascular-Kidney-Metabolic Health, Tyler A Jacobson, Mark D Huffman, Et Al. Mar 2025

Dried Blood Spots To Assess Cardiovascular-Kidney-Metabolic Health, Tyler A Jacobson, Mark D Huffman, Et Al.

2020-Current year OA Pubs

Dried blood spot sampling offers a scalable strategy to close diagnostic gaps and improve global surveillance for cardiovascular-kidney-metabolic syndrome. However, assay performance and the extent of validity vary widely between biomarkers used in cardiovascular-kidney-metabolic health assessment under different settings and have not been well described. To fill this gap, we conducted a systematic search of the literature and a narrative synthesis through April 2024 and included reports with laboratory or field validation measuring biomarkers that can be used in cardiovascular-kidney-metabolic health assessment. We categorized assays into categories based on laboratory validation: excellent performance (r>0.95 with gold standard methods and …

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First Record Of Nesting Ecology And Tumor-Forming Disease In Endangered Green Turtles (Chelonia Mydas) On Taiping Island, Taiwan, Tsung-Hsien Li, Po-Yu Wu, Ming-An Tsai Mar 2025

First Record Of Nesting Ecology And Tumor-Forming Disease In Endangered Green Turtles (Chelonia Mydas) On Taiping Island, Taiwan, Tsung-Hsien Li, Po-Yu Wu, Ming-An Tsai

The Thai Journal of Veterinary Medicine

Taiping Island is an important sea turtle nesting site in Taiwan. However, information on the nesting ecology on Taiping Island is still limited. The present study was conducted between 26 April and 3 June 2023 with the objective of collecting primary data on the sea turtle species that nest on the island. A total of 20 individual nesting green turtles were identified. No other sea turtle species were recorded nesting during this period. Five percent of nesting sea turtles had external tumors. The mean curved carapace length of all nesting female turtles was 98.2 cm. A total of 28 clutches …

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The Shorthorn: March 27, 1922 Mar 2025

The Shorthorn: March 27, 1922

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: March 20, 1922 Mar 2025

The Shorthorn: March 20, 1922

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: February 06, 1922 Mar 2025

The Shorthorn: February 06, 1922

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: January 30, 1922 Mar 2025

The Shorthorn: January 30, 1922

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: November 05, 1921 Mar 2025

The Shorthorn: November 05, 1921

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: October 17, 1921 Mar 2025

The Shorthorn: October 17, 1921

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: October 24, 1921 Mar 2025

The Shorthorn: October 24, 1921

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: August 1920 Mar 2025

The Shorthorn: August 1920

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

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The Shorthorn: June, 1919 Mar 2025

The Shorthorn: June, 1919

The Shorthorn Newspaper Collection: 1910s

No abstract provided.

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The Shorthorn: April, 1919 Mar 2025

The Shorthorn: April, 1919

The Shorthorn Newspaper Collection: 1910s

No abstract provided.

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Targeting School Shootings: Using Three Warning Signs - Animal Abuse, Domestic Violence, And Conduct Disorder - To Help Prevent Massacres, Phyllis Coleman Mar 2025

Targeting School Shootings: Using Three Warning Signs - Animal Abuse, Domestic Violence, And Conduct Disorder - To Help Prevent Massacres, Phyllis Coleman

Widener Commonwealth Law Review

Whether packing a superhero lunchbox for their five-year-old’s first day in a public kindergarten just down the block or preparing their twenty-two-year-old for his freshman year at an Ivy League law school 2,000 miles away, parents across the country are terrified by images of panicked children running from schools while an active shooter tries to slaughter as many students, faculty, and staff as he can. But, despite these widespread fears, and numerous governmental and other investigative studies, the only real consensus seems to be that these are horrific, destructive attacks that should stop. The difficulty lies in finding agreement about …

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Northern Red-Legged Frog Use Of A New Under-Road Crossing And Adjacent Upland Habitat, Alyson W. Yates, Catherine De Rivera Mar 2025

Northern Red-Legged Frog Use Of A New Under-Road Crossing And Adjacent Upland Habitat, Alyson W. Yates, Catherine De Rivera

Urban Ecosystem Research Consortium of Portland/Vancouver

A population of northern red-legged frogs (Rana aurora) located in northwest Portland must make a perilous crossing over U.S. Hwy 30 to access their breeding habitat in the floodplain of the Willamette River. To address the significant frog mortality that has historically resulted from this seasonal crossing, the Oregon Department of Fish and Wildlife managed the installation of an under-road crossing structure, completed in October 2024. To date, no studies have documented the effectiveness of crossing structures installed for R. aurora use, and few studies have examined their effectiveness for amphibians after installation. To meet these needs, our research will …

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Patterns In Human-Wildlife Conflict In The Portland Metro Area And Implications For Coexistence, Dave Keiter, Peter Iacono, Lindsey Sanders, Ben Cate Mar 2025

Patterns In Human-Wildlife Conflict In The Portland Metro Area And Implications For Coexistence, Dave Keiter, Peter Iacono, Lindsey Sanders, Ben Cate

Urban Ecosystem Research Consortium of Portland/Vancouver

The Oregon Department of Fish and Wildlife (ODFW) is routinely contacted for technical advice and assistance in addressing real or perceived human-wildlife conflict across the state. Improved understanding of patterns of conflict between humans and wildlife in urban ecosystems can help to identify ways to reduce perceived conflict and guide targeted education and outreach campaigns to benefit human-wildlife coexistence in urban areas. We analyzed 2,874 reports of human conflict with wildlife received by ODFW wildlife biologists in the Portland metro area from 2022-2024. Our objectives were to 1) identify the wildlife species most frequently involved in real or perceived conflict …

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Utilizing Roadkill Salvage To Bolster Chronic Wasting Disease Surveillance Data In Urban Areas, Steph Doorly, Trever B. Gelling Mar 2025

Utilizing Roadkill Salvage To Bolster Chronic Wasting Disease Surveillance Data In Urban Areas, Steph Doorly, Trever B. Gelling

Urban Ecosystem Research Consortium of Portland/Vancouver

Chronic wasting disease (CWD) is a Transmissible Spongiform Encephalopathy that is always fatal to members of the deer family (Cervidae). CWD poses a unique challenge for wildlife managers as there is no cure or treatment for infected individuals, it remains transmissible and persistent in the environment, and symptoms become evident only after a long incubation period. The disease has yet to be detected in Oregon. CWD can impact trophic systems, economies, and sources of first foods. The Oregon Department of Fish and Wildlife’s (ODFW) CWD management plan includes increased surveillance through diversified sampling efforts, and public education and outreach. Monitoring …

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The Grubonian: February 14, 1919 Mar 2025

The Grubonian: February 14, 1919

The Shorthorn Newspaper Collection: 1910s

No abstract provided.

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