Digital Commons Network^™

A Punishment That Harms Everyone And Benefits No One: An Analysis Of The Use Of Solitary Confinement Under Common Sociological Theories Of Punishment, Allison Lampert

Et Cetera

In the United States, experts estimate that nearly 100,000 incarcerated individuals are held in solitary confinement. While individuals can be held in solitary confinement for a variety of reasons, many are placed in lockdown because they have untreated mental illnesses, have committed some sort of minor disciplinary infraction, are need of protection, or for unpopular personal beliefs. In other words, solitary confinement is used as a broad catch-all to a wide range of low-level and nonviolent misbehaviors. This note argues that solitary confinement is an unjustifiable mode of punishment as analyzed under two commonly cited sociological theories of punishment: retributivism …

Hepatic Manifestations Following Gene Therapy, Akash Roy, Shalini Bansal, Anand Kulkarni, K. Rajender Reddy

SKMC Student Presentations and Publications

Gene therapy involves the introduction of genetic materials, most commonly using viral vectors, to alter gene expression to ameliorate or cure disease symptoms with minimal adverse events. While interest in gene therapy has been on the increase, concerns have arisen about the potential for hepatotoxicity, which arises from diverse mechanisms. While viral vectors can produce dose-dependent hepatotoxicity secondary to integration, immune responses appear to be the primary driving mechanism. A mild increase in aminotransferases is the most common hepatic manifestation, occurring variably in 20%-80%, while there has been rare progress to acute liver failure. The occurrence of hepatotoxicity is unpredictable …

The Controversy And Ethics Behind Zoos, Merin R. Boucher

Intertext

No abstract provided.

How To Go To Hell: The Ethics Of Religious Interpretation, Ilhy Gomez Del Campo Rojas

Intertext

No abstract provided.

Complete Issue - Intertext 2025, Intertext Journal

Intertext

No abstract provided.

April 24, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Grizzly, April 24, 2025, Kate Horan, Renee Washart, Nathaniel Nerone, Sidney Belleroche, Erin Ewing, Hadley Whitman

Ursinus College Grizzly Newspaper, 1978 to Present

Experimental Film Event With Jen Proctor • Golf Centennial Conference Championships • Portrayals of Identity • Yik Yak Ban and Online Conduct • Tau Sigma Gamma Talks Events, Friendships and Recruitment • A List of Unserious Reasons Why You Should Join The Grizzly • Bears' Track Roars On • Men's Lacrosse Fights Through Challenging Season

Proteomic Comparison Of Canine Gallbladder Versus Hepatic Neuroendocrine Neoplasms, Nadia Richmond

LSU Master's Theses

Hepatobiliary neuroendocrine neoplasms (HBNENs) are uncommon tumors in people and dogs, and the limited understanding of their biologic behavior often poses a diagnostic and prognostic challenge in the clinical setting. Though only a low number of cases have been described in dogs, there is evidence to indicate that primary gallbladder NENs may carry a more favorable prognosis compared to primary hepatic NENs. The emergence of liquid chromatography-mass spectrometry (LC-MS) in proteomic analysis has permitted large-scale analysis of neoplastic proteomes, allowing for better understanding of tumor pathophysiology while simultaneously enabling the rapid identification of protein biomarkers. Previous work in our laboratory …

A Brief Study In Aristotelian Ethics, Robert Wallace

Bryant Literary Review

No abstract provided.

The Day I Buried Myself, Lauren Robertson

Bryant Literary Review

No abstract provided.

Advanced Manufacturing Of Multifunctional Shape Memory Polymer Composites And Self-Healing Systems, John B. Konlan

LSU Doctoral Dissertations

The need for multifunctional light weight structures for engineering applications is on the rise. Multifunctional composites are desired because of their ability to combine multiple functionalities into one structure. The advantages of a high strength-to-weight ratio of multifunctional composites make them desirable and suitable for use in energy-efficient applications. Shape-memory polymers (SMPs) have attracted interest over the past several decades because of their multifunctional nature. They have found use in many applications such as aerospace, satellites, automobiles, textiles, and biomedical devices, where lightweight and multifunctionality are key. The self-healing nature of most SMPs makes them suitable for use in lightweight …

Induction Of Cardiac Fibulin-4 Protects Against Pressure Overload-Induced Cardiac Hypertrophy And Heart Failure, E D Van Deel, C M Halabi, Et Al.

2020-Current year OA Pubs

The prevailing view of fibulin-4 deficient mice is that the cardiac phenotype is the result of aortic and/or valvular disease. In the present study, we have tested whether the cardiac phenotype is, at least in part, the consequence of primary cardiac effects of fibulin-4. We have found fibulin-4 expression to be activated throughout the myocardium in wildtype (fibulin-4

Enhancing Cnns Via Structural Intervention With Xgboost, Cemil Emre Yavas, Lei Chen, Christopher Kadlec, Jongyeop Kim

Computing: Faculty Publications

This research investigates a novel hybridization strategy between Convolutional Neural Networks (CNNs) and gradient-boosted decision trees to enhance image classification accuracy. While conventional approaches focus on optimizing either CNN architectures or machine learning algorithms independently, we propose that intervening in the architecture itself—by strategically replacing the dense classifier portion of the CNN with a tree-based learner—can yield superior results. In our study, we construct a CNN composed of three convolutional blocks, each followed by ReLU activation, max-pooling, and dropout layers. Instead of proceeding through the final dense layers, we extract features immediately after the Flatten layer and input them into …

Stuffed Animals And Adults, Anna R. Reed

2025 Student Academic Showcase

Recently, stuffed animals have resurged in interest among children and adults. For example, in 2023, Squishmallows won Plush Toy of the Year at the annual Toy Association Awards. We surveyed 184 adult participants (18 or older) to identify who owns stuffed animals. We were interested in whether certain personality variables predict who has these toys and why adults retain interest in these toys. Among our participants, 71.7% owned stuffed animals. We hypothesized that adults with higher stress/anxiety would report increased likelihood of owning stuffed animals. This hypothesis was supported. An independent samples t-test showed that participants with stuffed animals reported …

A Hybrid Deep Learning-Based Approach For Visual Field Test Forecasting, Ashkan Abbasi, Sowjanya Gowrisankaran, Wei-Chun Lin, Xubo Song, Bhavna Josephine Antony, Gadi Wollstein, Joel Schuman, Hiroshi Ishikawa

Wills Eye Hospital Papers

OBJECTIVE: Longitudinal assessment of visual field (VF) testing is essential in glaucoma management. Conventional VF forecasting methods require numerous prior tests, while deep learning techniques have shown promising results with fewer tests. This study introduces a hybrid deep learning framework to enhance flexibility and accuracy in VF test forecasting.

DESIGN: A retrospective longitudinal study using deep learning-based VF forecasting models.

SUBJECTS AND CONTROLS: A total of 1750 subjects (healthy and glaucoma patients) with 19 437 Humphrey VF (24-2 Swedish Interactive Threshold Algorithm) tests collected from longitudinal glaucoma cohorts at the University of Pittsburgh and New York University.

METHODS: Three deep …

Empowering Undecided Students: Fostering Self-Authorship Through Academic Advising Practices, Erin E. Westberg

Masters Projects

More students are entering college undecided about their major, yet many academic advisors are not equipped with the proper tools to holistically support this population. Undecided students often experience self-doubt, external pressures, and difficulty identifying a major that aligns with their personal interests and goals. Without holistic support, this may delay their time to graduation or cause them to choose a path that doesn’t feel right for them. The purpose of this project is to provide academic advisors with a framework to better support undecided students through the use of self-authorship. This approach encourages students to reflect on their values, …

Difference In Clinical Presentation And Surgical Outcomes In Pediatric And Adult Patients With Chiari Malformation Type 1: A Single Center Retrospective Study, Erik Öhlén, Victor Gabriel El-Hajj, Victor E. Staartjes, Pascal Jabbour, Erik Edström, Adrian Elmi-Terander

Department of Neurosurgery Faculty Papers

INTRODUCTION: Chiari malformation type 1 (CM1) is a common congenital disorder affecting both children and adults. Although pediatric and adult CM1 patients share many characteristics, the differences between the groups are not fully described.

METHOD: A comparative analysis was made of two previously defined cohorts of adult and pediatric non-syndromic CM1, surgically treated at the study center. Clinical outcomes were assessed using the Chicago Chiari outcome scale (CCOS) and radiological outcomes were measured as change in cerebellar tonsil and syringomyelia status.

RESULTS: A total of 209 patients (73 pediatric, 136 adults) were included, with median ages of 11 and 33 …

A Population Study Of The Freshwater Turtles Of The Recently Expanded Lake Hydaway In Campbell County, Virginia, Joshua Sorenson

Senior Honors Theses

Freshwater turtles are an important part of the ecological systems in central Virginia. At the recently expanded Lake Hydaway, there are several turtle species for which their population characteristics were unknown, especially the prolific Eastern Painted Turtle (Chrysemys picta picta) and Red-bellied Cooter (Pseudemys rubriventris). For five weeks, the lake was surveyed for turtles using hoop nets, and the turtles were marked and measured. Population characteristics such as carapace length and sex ratio for the Eastern Painted Turtle and Red-bellied Cooter were calculated, as well as population estimates for those two species. The Red-eared Slider ( …

Killing The Buddha On The Appalachian Trail: Walking On Through Self-Doubt And Aging, Sidney Gavel

The Southeastern Librarian

John Turner Athens: University of Georgia Press, 2024 ISBN: 9780820367736 364 p. $29.95 (Pbk)

Quaker Campus, April 24, 2025 (Vol. 23, Issue 13), Whittier College

Quaker Campus

No abstract provided.

Kenyon Collegian - April 24, 2025

The Kenyon Collegian

No abstract provided.

April 24, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Fishing For Solutions: Compensation For Bycatch Reduction In The Gulf Of Mexico Shrimp Fishery, Daniel W. Harris

LSU Master's Theses

Bycatch, unintentionally caught non-target species, harms the profitability of commercial fishing operations and leads to death and injury of hundreds of thousands of marine animals per year. In the Gulf of Mexico, commercial shrimpers are required to use a bycatch reduction device (BRD). Better BRDs are being tested to further reduce bycatch. Because their use will not be mandatory, it is important to measure shrimper willingness to voluntarily adopt this conservation technology to predict potential fleet participation. This study uses contingent valuation to elicit commercial shrimpers’ willingness to accept compensation for using these new devices.

We employ an incentivized payment …

Examining The Impact Of Widespread Disease On The Economy, Ryan Howell

Honors College Theses

Over centuries, disease has been an instigator of economic change. From the Black Death and the overturning of feudalism to the Spanish flu and its relationship with World War 1, pandemics have a profound effect on the social, political, and economic climate of the affected areas. In 2020, COVID-19 began in Wuhan, China and spread across the world rapidly and unexpectedly. The world economy was forced into a recession with major effects on industries such as airlines, energy, and automobiles. While some industries made smooth recoveries, the pandemic undeniably altered the way business is conducted. The shift between in-person and …

Idh Status Dictates Ohsv Mediated Metabolic Reprogramming Affecting Anti-Tumor Immunity, Upasana Sahu, Matthew P Mullarkey, Sara A Murphy, Joshua C Anderson, Vasanta Putluri, Abu Hena Mostafa Kamal, Jun Hyoung Park, Tae Jin Lee, Alexander L Ling, Benny A Kaipparettu, Ashok Sharma, Nagireddy Putluri, Pamela L Wenzel, Christopher D Willey, E Antonio Chiocca, James M Markert, Balveen Kaur

Faculty, Staff and Student Publications

Identification of isocitrate dehydrogenase (IDH) mutations has uncovered the crucial role of metabolism in gliomagenesis. Oncolytic herpes virus (oHSV) initiates direct tumor debulking by tumor lysis and activates anti-tumor immunity, however, little is known about the role of glioma metabolism in determining oHSV efficacy. Here we identify that oHSV rewires central carbon metabolism increasing glucose utilization towards oxidative phosphorylation and shuttling glutamine towards reductive carboxylation in IDH wildtype glioma. The switch in metabolism results in increased lipid synthesis and cellular ROS. PKC induces ACSL4 in oHSV treated cells leading to lipid peroxidation and ferroptosis. Ferroptosis is critical to launch an …

Montana Kaimin, April 24, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The P130cas-Crk/Crkl Axis: A Therapeutic Target For Invasive Cancers Unveiled By Collaboration Among P130cas, Crk, And Crkl., Pegah Farhadi, Taeju Park

Manuscripts, Articles, Book Chapters and Other Papers

Numerous studies have documented the involvement of p130Cas (Crk-associated substrate) in a wide range of cellular processes across different types of cells. These processes encompass cell transformation, the connection between the extracellular matrix and the actin cytoskeleton, cell migration and invasion, and cardiovascular development. Moreover, p130Cas has been associated with the regulation of various physiological processes, including mammary, bone, brain, muscle, and liver homeostasis. The diverse functions of p130Cas can be attributed to its possession of multiple protein-protein interaction domains, which sets it apart as a unique class of adaptor protein. It is well established that p130Cas interacts critically with …

Assessment Of The Relationship Between Particulate Matter Level And Respiratory Diseases In Dogs And Cats In Bangkok, Thailand, Nattawan Tangmahakul, Janenisa Klomklao, Damisa Thanyapornsombat, Tuangphon Lertsubkhajohn, Wiphawa Piboonlapudom, Satraporn Mettaviparee, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

Particulate matter (PM) 2.5 has become a serious pollution concern in many countries, including Thailand. Due to its small particle size, PM2.5 can penetrate deep into pulmonary tissues, posing health risks to humans. Furthermore, it is hypothesized that PM2.5 may also cause respiratory diseases in dogs and cats. This study aimed to evaluate a relationship between PM2.5 levels and the number of dogs and cats visiting due to respiratory problems in Bangkok, Thailand, and to investigate potential environmental factors that may contribute to these health outcomes. A total of 184 dogs and 73 cats were included in the study. Medical …

Survey And Analysis Of Rumen Microbiota In Yaks At Different Growth Stages, Shengwei Jin, Xinyue Liu, Yin-Cang Han, Yong-Gang Sun, Wei-Qin Ding, Ya-Qian Liu, Fa-Jie Gou, Jian-Yu Chen

The Thai Journal of Veterinary Medicine

This study investigated changes in the richness and composition of the rumen microbiome in yaks at various developmental stages. Eighteen healthy male yaks at the ages of 5 months (M5), 12 months (M12), and 24 months (M24) had samples of their rumen digesta taken for 16S rRNA gene sequencing. The 11087 amplicon sequence variations (ASVs) in total were found; the M5, M12, and M24 groups had 3585, 1146 and 5545 distinct ASVs, respectively. Alpha diversity indices Chao, Shannon, Sobs, and ace indicated significant differences among the groups. The principal coordinate analysis (PCoA) indicated significant changes in microbial community composition across …

Impact Of Colostrum Lactose Concentration In Relation To Metabolomic Profiles On Kid Growth Performance Of Black Bengal Goats, Tien Thi Phuong Vo, Chollada Buranakarl, Sumonwan Chamsuwan, Sumpun Thammacharoen, Morakot Nuntapaitoon, Sarn Settachaimongkon

The Thai Journal of Veterinary Medicine

Colostrum composition, including lactose concentration in relation to metabolomic profiles on kids’ growth performance of Black Bengal goats, has not yet been elucidated. Macronutrients, including lactose and metabolomic profiles, were determined in 37 colostrum samples using MilkoScan and 1H-nuclear magnetic resonance technique, respectively. Kids’ growth performance, including birth weight, average daily gain at 0–4 weeks (ADG0-4W), 4–8 weeks (ADG4-8W), and wean weight were determined. A total of 51 metabolites were detected in the colostrum. From the general linear model for univariate analysis, kids born from multiple litter sizes showed lower ADG during the first month postpartum (P = 0.004). …