Digital Commons Network^™

Antioxidant Effects Of Dimethyl Fumarate In Siv-Infected Rhesus Macaques May Indicate Its Use As A Neuroprotective Adjunct In Hiv Treatment, Adam K. Adelsberg, Yoelvis Garcia-Mesa, Halvor Juul, Dennis L. Kolson

Research Day

INTRODUCTION: Dimethyl fumarate (DMF) is an oral prodrug that is FDA approved for the treatment of multiple sclerosis. DMF is metabolized to monomethyl fumarate and able to cross the blood-brain barrier to illicit its central nervous system (CNS) affects. DMF is an antioxidant/anti-inflammatory that acts at the level of gene transcription through the Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. We assessed the potential neuroprotective effects of DMF in HIV infection by using the rhesus macaque simian immunodeficiency virus (SIV) infection model. We hypothesized that DMF would increase the expression of antioxidant enzymes and subsequently reduce central nervous system …

Topical Antibiotics, Over-The-Counter Products, And Standard Gauze Dressings: A Review Of Postoperative Surgical Site Infection And Wound Healing Management, Emily M. Garelick, Jacob E. King, David Kasper

Research Day

Proper wound healing and prevention of surgical site infections (SSI) are critical in postoperative patient care. According to the CDC, SSIs account for almost twenty percent of all healthcare-associated infections and cause an annual cost of an estimated $3.3 billion annually. Wound healing time, as well as cosmetic results, also play an important role in postoperative wound care. Currently there is not a consensus standard of care for topical treatments to address these issues. This study aims to explore various topical treatments that prevent SSI and encourage effective healing.

A search was conducted on PubMed using the algorithm: ([Vaseline] OR …

Protein Kinase C Delta Peptide Activator Provides Protection During Hypoxia/Reoxygenation And Elicits Significant Anti-Cancer Effects In Vitro, Juliet M. Melnik, Qian Chen, Robert J. Barsotti, Lindon H. Young

Research Day

Introduction

Protein kinase C delta (PKCδ) activation is known to inhibit NOX-2/superoxide (SO) release in polymorphonuclear leukocytes (PMNs) and elicit cardioprotective effects in ischemia-reperfusion (I/R) injury. Augmenting PKCδ activity also promotes tumor suppressive effects via apoptosis. This study examined the cardioprotective and anticancer effects of PKCδ peptide activator (PKCδ+) in endothelial cells and cardiomyocytes, cardiovascular cells particularly susceptible to oxidative damage due to their high concentration of mitochondria.

Methods

Hypoxia/Reoxygenation: Human umbilical vein endothelial cells (HUVECs) and rat cardiomyocytes (H9C2 cells), were cultured at 37°C in EBM-2 medium and DMEM, respectively and pretreated with PKCδ+ (Myr+MRAAEDPM) (0.25-5μM) or untreated …

Nourish Chicago: Cultivating Health And Sustainability In Low-Income Communities Through Accessible Education And Engaging Activities, Audrey Kho

Undergraduate Research and Engagement Symposium

“Nourish Chicago: Cultivating Health and Sustainability in Low-Income Communities through Accessible Education and Engaging Activities” seeks to improve nutritional literacy and sustainable food choices by educating communities on natural food dyes as healthier alternatives to artificial colorants. Participants learn about the chemical characteristics, health advantages, and culinary uses of plant-based pigments like turmeric, hibiscus, beetroot, and butterfly pea flower through engaging food science workshops and demonstrations. Practical tests demonstrate food preparation, color stability, and pH sensitivity, enabling people to make educated nutritional decisions. This project promotes lifelong scientific literacy and improved eating habits by increasing awareness of food color substitutes.

Comparing Crawling Development In Children With Limb Loss/Limb Difference To Typically Developing Children, Larissa Brehm, Analise Oliver, Maya Tulchinsky, Diana Mansouri, Mark Daniel Geil

Symposium of Student Scholars

The CDC removed crawling as a milestone for children developing as of 2022[1], due to insufficient data and definitions. The purpose of this study was to collect data using a pressure mat and quadrupedal gait software on infant crawling patterns in children with limb loss or limb difference (LLD) and typically developing (TD) children in order to understand both how children with LLD crawl, and which parameters detect differences. The data collected was then converted into measurable outcomes such as cadence, velocity, weight distribution, and stance support.

The long-term objective of this study is to understand the quantitative parameters that …

Can A Ceh-27/Nkx2.1 Transgene Rescue Ceh-27 Neurodevelopmental Defects?, Meryl Gilmore, Martin L. Hudson

Symposium of Student Scholars

When the development of an organism’s nervous system is interrupted or altered, it can significantly impact that organism’s ability to survive and function properly. In our lab, we use a species of nematode called Caenorhabditis elegans as a model organism to characterize the roles of important transcription factors in human neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD). Utilizing C. elegans makes analyzing this process in a lab very easy for many reasons; they are very small, have a rapid life cycle, invariant cell lineage, transparent bodies, and most importantly, around 80% of their genes have human orthologs. In …

Renal Protection By Upadacitinib In Ischemia-Reperfusion Injury: Insights From A Male Rat Model", Furqan Hashim Hussein, Najah R. Al Mosawi

Maaen Journal for Medical Sciences

Renal ischemia reperfusion damage is a severe syndrome that can develop after kidney transplants, kidney-targeting surgery, or other clinical situations that restrict blood flow to the kidneys. This study evaluated the effectiveness of the JAK1 inhibitor upadacitinib in lowering RIRI in a rat model. The rats were stratified into 4 groups after a 1 week acclimatization period. The study found that HMGBox and inflammatory substances like TNF-α and IL-6 impact RIRI. Upadacitinib's inhibition of the JAK1/STAT3 pathway minimized RIRI by significantly lowering these molecules. It also significantly reduced NF-κB activation, thereby reducing the inflammatory response and programmed cell death. The …

How To Write A Successful Research Manuscript: Back To Basics, Nayda Parisio Poldiak, Nancy Crossley

HCA Healthcare Journal of Medicine

Writing a research manuscript is a meticulous process necessary for effective communication of scientific findings. In this article, we cover the key concepts and steps involved in crafting a well-structured manuscript. Research manuscripts use a formal structure with discrete sections that facilitate data review and interpretation. The opening section is a structured abstract, which summarizes the entire manuscript in about 300 words and highlights the research problem, using the headings Background, Methods, Results, and Conclusion. The introduction provides context, states the research question and justifies its significance. The methods section details the study design, data collection, and analysis procedures. The …

Evaluation Of The Accuracy And Reliability Of 3d Cameras For Craniofacial Anthropometry Compared To Conventional Methods: A Systematic Review, Akanksha Chandiwala, Kanhoba Keluskar

Taiwanese Journal of Orthodontics

Objectives: To assess the reliability and accuracy of three-dimensional (3D) camera for Craniofacial Anthropometry in comparison with direct measuring methods. Materials and methods: A comprehensive search of the specialized databases Pubmed/ MEDLINE, Science Direct, Google Scholar, OpenGrey, and other institutional repositories was performed for including the studies which assess the reliability and accuracy of various 3D Cameras for Craniofacial Anthropometry in comparison with direct Anthropometric measurements. Quality assessment was carried out with JBI critical appraisal checklist for analytical cross sectional studies. Results: Seven studies evaluating the accuracy and reliability of 3D cameras were included in this study. Studies comparing 3D …

Investigation Of Factors Influencing Craniofacial And Dental Morphological Changes In Skeletal Class Iii Orthognathic Surgery With Machine Learning Approach: Literature Review, Muhammad Izzah Abdillah, Johnson Hsin-Chung Cheng, Daniel De-Shing Chen, Sam Li-Sheng Chen, Baharuddin M Ranggang, Ardiansyah S Pawinru

Taiwanese Journal of Orthodontics

Objective Orthognathic surgery is a transformative solution for skeletal Class III malocclusion. This review explores factors affecting skeletal, dental, and soft tissue changes in these patients and examines the integration of machine learning (ML) in treatment management to uncover patterns within large datasets. Materials and Methods Studies were selected from Google Scholar, PubMed, and ScienceDirect using keywords such as "(affecting factor OR predisposition) AND (skeletal class III OR skeletal class 3) AND (orthognathic surgery OR surgical orthodontics)," "Morphology changes in skeletal class III orthognathic surgery," "Machine learning in dentistry," and "Machine learning in orthodontics." Most reviewed articles were published in …

Asthma Exacerbation In Pregnancy And The Effects On The Fetus, Jaclyn Vanberkum, Daisy Ramirez, Julia Gonazlez, Haneen Kittaneh

RESP 1102 Intermediate Respiratory Care

Asthma is one of the most common chronic conditions affecting pregnant women and poses notable risks to both maternal and fetal health. Inadequate asthma control during pregnancy is associated with increased complications such as preeclampsia, preterm delivery and low birth weight. As a result, effective asthma management is essential throughout gestation. This paper explores the physiological changes in pregnancy that influence asthma, the potential consequences of uncontrolled symptoms and evidence-based treatment approaches. Current clinical guidelines emphasize the importance of inhaled corticosteroids and bronchodilators while minimizing systemic steroid use. Patient education, regular monitoring and a multidisciplinary approach are key to optimizing …

Team Software Design Analysis, Jaden Juyoung Yu, Elisabeth Jean Elgin, Vasilia Cecile Douglas, Alexander Nicholas Wood, Jason Alexander Lake

Honors Capstone Projects and Theses

No abstract provided.

The Role Of Individual Values In Bryant University's Sustainability Efforts, John Boccuzzi Iii

Honors Projects in Data Science

This research examines student, faculty, and staff perspectives on sustainability at Bryant University, with the goal of understanding how individual values align with the university's environmental initiatives. The objective is to assess perceptions of Bryant's current sustainability practices, explore how effectively these efforts are communicated across campus, and identify potential gaps between institutional action and community awareness. To achieve this, the study gathers qualitative data through an open-ended survey and applies sentiment analysis to interpret student attitudes toward sustainability. By analyzing these responses alongside Bryant's sustainability marketing efforts, this research will identify gaps between student engagement and institutional messaging The …

La Niebla, El Delirio, Cindy Catherine Martínez Martínez

Ciencias Sociales, Humanidades y Ciencias Políticas

Con un lenguaje fresco y sencillo, La niebla, el delirio realiza un trayecto imaginario por los mundos que trae la autora desde su memoria. Ente Trenes vagón capilla ardiente y vagón cementerio, el viaje sucede entre lugares de la infancia -"aparecimiento único de una lejanía, por más cerca que pueda estar"- y lugares inexistentes. Hay varios poemas en los que se percibe el equilibrio entre emoción, ritmo y tema. El libro fue escrito hace una década y algunos poemas fueron publicados en revistas y antologías nacionales, pero no se había editado como unidad; por lo que este poemario es …

Sexual And Gender Minority Individuals In Our Community: Policy Recommendations To Address Discrimination-Related Stresses, Emylia N. Terry

Lincy Institute Events

Sexual and gender minority (SGM) individuals face a wide range of mental and physical health challenges, which contribute to higher rates of suicide. SGM individuals encounter distress, discrimination, and in some cases, harmful anti-LGBTQIA+ laws and policies that contribute to additional mental and physical health stress. A web-based survey of 1,034 SGM participants in the United States measured the types and frequency of discrimination occurrences and related distress. The survey considers the variety of interactions between individuals and their relationships, while also measuring the community and societal factors that affect health outcomes for SGM individuals. This research evaluates many variables …

Meet The Pulse Editorial Board

PULSE: A Student Publication of Literary & Artistic Works

No abstract provided.

In Lectio Divina, David Ting Com 25

PULSE: A Student Publication of Literary & Artistic Works

No abstract provided.

Pulse, Vol. 4 Spring 2025

PULSE: A Student Publication of Literary & Artistic Works

No abstract provided.

A Comprehensive Review On Intrusion Detection In Internet Of Things (Iot) And Industrial Internet Of Things (Iiot) Systems, Umar Ibrahim, Mutasem Jarrah

Journal of King Abdulaziz University: Computing and Information Technology Sciences

As computer networks and technologies become increasingly embedded in our daily lives, there is growing concern about detecting intrusions and cyberattacks. It’s still difficult to detect intrusions in computer networks effectively. This is due to the recent trend of cyber attackers posing as intrusion detection systems (IDS) by altering packet contents. Additionally, a large number of new devices are added to computer networks daily. Security concerns in computer networks are also being brought up by these new devices. In the context of the Internet of Things (IoT) and the industrial Internet of things (IIoT), this study aims to present an …

Commonwealth Times 2025-04-30

Commonwealth Times, 1969-

No abstract provided.

Crónicas De Gastronomía Ancestral De La Provincia De Ubaté (Cundinamarca), Johanna Andrea Gil Palacios, Nancy Milena Valiente Triana, Nohora Liliana Agudelo Rodríguez, Carlos Alfonso López Urquina, Cristian Ballén Guarín, John Henry Vásquez Calderón

Institucional

Este libro es un viaje maravilloso que conduce al lector a comprender la estrecha relación entre territorio y gastronomía. Cada accidente geográfico representa un reto de sus pobladores que potencia su creatividad para sobrevivir e implica el esfuerzo para que broten frutos que se puedan llevar a la mesa, en sendas preparaciones que se van heredando entre generaciones. Las personas cuentan llenas de orgullo las gestas que han vivido en torno a la comida, las reuniones familiares, las fiestas patronales, y las convierten en la mejor vitrina de su identidad y la celebración de las cosechas. Es un verdadero placer …

Utah State University Commencement, 2025 – Southwest Campus, Utah State University

Commencement Programs

2025 Commencement Ceremony for the Southwest Campus of Utah State University.

Utah State University Commencement, 2025 – Main Campus, Utah State University

Commencement Programs

2025 Commencement Ceremony for the Main Campus of Utah State University.

“Virtual Reality And Creativity: Evaluating Immersive Painting Experiences And Art-Based Mindfulness” Presented By Heli Puhakka, Heli Puhakka

Staff Scholarship - Australia & Dubai

New affordable head-mounted displays and interactive virtual technologies provide opportunities for researchers and practitioners to create and experience mindfulness. The use of virtual reality for art-based mindfulness practices is novel and promotes full-body, immersive experiences to improve mood, however, researchers and practitioners have a limited understanding of mindfulness and creativity in the virtual environment. This paper identifies the research gap by examining how active art-based mindfulness practices in virtual reality promote mindfulness, compared to passive methods such as viewing a virtual image to experience relaxation. Fourteen participants were interviewed in the qualitative ethnographic study. Methods included semi-structured interviews, direct observation, …

Testing For Normality In Regression Models: Mistakes Abound (But May Not Matter), Stephen Midway, J. Wilson White

Faculty Publications

This study examines the misuse of normality tests in linear regression within ecology and biology, focusing on common misconceptions. A bibliometric review found that over 70% of ecology papers and 90% of biology papers incorrectly applied normality tests to raw data instead of model residuals. To assess the impact of this error, we simulated datasets with normal, interval, and skewed distributions across various sample and effect sizes. We compared statistical power between two approaches: testing the whole dataset for normality (incorrect) versus testing model residuals (correct) to determine whether to use a parametric (t-test) or nonparametric (Mann-Whitney U test) method. …

Assessing The Behavioral Impact Of Pyridostigmine Bromide In Rats, Noah A. Martin

Honors Theses

Pyridostigmine bromide (PB) is an organophosphate (OP) nerve agent prophylactic used to protect warfighters against chemical warfare agents. OPs inhibit the neural enzyme acetylcholinesterase (AChE) in the brain. This leads to the buildup of acetylcholine, causing respiratory failure, seizures, and death. PB functions by inhibiting ~30% of peripheral AChE temporarily, protecting the enzymes so that the body is able to restore sufficient cholinergic function post-exposure. PB does not cross the blood-brain barrier, though it may still indirectly affect toxicity in the brain due to repeated AChE inhibition throughout treatment, or by inhibition of non-target ChE’s in the blood. The aim …

Penggunaan Peraga Visual Pada Program Pengabdian Masyarakat Di Wilayah Pesisir Dan Kepulauan Rawan Bencana, Abellia Anggi Wardani Dr., Anin N. Kumala, Caroline A. Windah, Shintya Shintya

Bhakti: Jurnal Pengabdian Masyarakat

Indonesia’s coastal and archipelagic regions are vulnerable to disasters such as earthquakes, tsunamis, and floods. In this context, community service activities require participatory and educational approaches that are easily understood by people of various ages and backgrounds. This article discusses the use of visual aids—such as infographics, leaflets, animated videos, illustrations, and x-banners—as tools for disaster education. Through a literature review of four articles on community service programs, this study finds that visual aids are effective in increasing disaster risk awareness, reinforcing visual memory of mitigation procedures, and engaging vulnerable groups such as children and indigenous communities. This approach also …

A Deadly Case Of Encephalopathy, Brenna Ostertag, Md, Gita D Gelfer, Andrea Roast

Providence Portland Medical Center Internal Medicine 2025

Introduction: Human prion disease are heterogenous groups of neurodegenerative disorders characterized by spongiform degeneration, astrogliosis, and neuronal loss in the central nervous system from misfolding and subsequent spread of the prion protein. This disease manifests rapidly and is often accompanied by visual and speech abnormalities, gait changes, and progressive encephalopathy. It is always fatal. Around 400 people are diagnosed with prion disease in the United States annually. Recent innovations in diagnostics using Real-Time Quaking Induced Conversion (RT-QuIC) has allowed for antemortem diagnosis of prion disease. Case Presentation: A 66-year-old male with a history of alcohol use disorder in remission and …

Dairy And Food Science Student Newsletter, April 30, 2025, Department Of Dairy And Food Science

Dairy and Food Science Student Newsletter

No abstract provided.

Community-Based Learning: Sustainability Capstone's Project To Increase Native Landscaping And Edible Landscapes At Usd, Haley Anciaux, Belle Gustaf, Josie Hamer, Rachael Holt, Emily Kahn, Paxton Roseland, Erin Smith, Meghann Elizabeth Jarchow

Sustainability & Environment Projects

This report describes the community-based learning project completed by the Sustainability Capstone (SUST 489) course in Spring 2025.