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Articles 26461 - 26490 of 733206
Full-Text Articles in Entire DC Network
Patulin As A Negative Regulator Of Wild-Type Elp1 Splicing In Familial Dysautonomia-Derived Cells, Katherine P. Cáceres Bravo
Patulin As A Negative Regulator Of Wild-Type Elp1 Splicing In Familial Dysautonomia-Derived Cells, Katherine P. Cáceres Bravo
FCRH Honors Program Theses
Although the human genome has a limited number of genes, alternative splicing allows the production of thousands of proteins. Alternative splicing is a regulated mechanism in which a messenger RNA (mRNA) synthesizes different proteins called isoforms, variants of the same protein that may have different cellular functions [1]. The unspliced sequence, also known as the primary transcript, results from the transcription of a genetic sequence by RNA Polymerase II, which produces an mRNA containing introns (non-coding regions) and exons (coding regions) [2]. The splicing process is catalyzed by the spliceosome, a ribonucleoprotein mega-particle composed of small nuclear ribonucleoproteins (snRNPs), U1, …
Energetic Cost Of Human Disturbance On The Southern Sea Otter (Enhydra Lutris Nereis), Heather E. Barrett, M. Tim Tinker, Gena Bentall, Birgitte I. Mcdonald
Energetic Cost Of Human Disturbance On The Southern Sea Otter (Enhydra Lutris Nereis), Heather E. Barrett, M. Tim Tinker, Gena Bentall, Birgitte I. Mcdonald
Faculty Research, Scholarly, and Creative Activity
With increased human populations and tourism in coastal areas, there is greater potential for disturbance of marine wildlife. Because of their high metabolic rates, sea otters (Enhydra lutris) are at particular risk of increased energetic costs due to human disturbance. We used scan surveys to monitor southern sea otter (E. l. nereis) activity and potential disturbance stimuli over 5 years (2015–2020) at 3 California, USA, study sites: Monterey, Moss Landing, and Morro Bay. We developed a process-based, hierarchical model of sea otter behavior, which we fit to survey data to examine how activity varies in response to the occurrence of …
Preclinical Development Of Genome Editing To Treat Duchenne Muscular Dystrophy By Exon Skipping, Made Harumi Padmaswari, Shilpi Agrawal, Christopher E. Nelson
Preclinical Development Of Genome Editing To Treat Duchenne Muscular Dystrophy By Exon Skipping, Made Harumi Padmaswari, Shilpi Agrawal, Christopher E. Nelson
Biomedical Engineering Faculty Publications and Presentations
Duchenne muscular dystrophy (DMD) is caused by loss-of-function mutations to the gene encoding dystrophin. Restoring the reading frame of dystrophin by removing internal out-of-frame exons may address symptoms of DMD. Therefore, the principle of exon skipping has been at the center stage in drug development for Duchenne muscular dystrophy (DMD) over the past two decades. Antisense oligonucleotides (AONs) have proven effective in modulating splicing sites for exon skipping, resulting in the FDA approval of several drugs using this technique in recent years. However, due to the temporary nature of AON, researchers are actively exploring genome editing as a potential long-term, …
Vicksburg: The Crowning Point Of The American Ulysses, Anthony Gruidl
Vicksburg: The Crowning Point Of The American Ulysses, Anthony Gruidl
Celebrating Scholarship and Creativity Day (2018-)
Thesis Paper and Presentation on a military analysis of the Vicksburg Campaign from the US Civil War, focusing on the generalship and leadership of General Ulysses S. Grant.
Toward Whole-Person Fit Assessment: Integrating Interests, Values, Skills, Knowledge, And Personality Using The Occupational Information Network (O*Net), Zihan Liu, Kevin A. Hoff, Chu Chu, Frederick L. Oswald, James Rounds
Toward Whole-Person Fit Assessment: Integrating Interests, Values, Skills, Knowledge, And Personality Using The Occupational Information Network (O*Net), Zihan Liu, Kevin A. Hoff, Chu Chu, Frederick L. Oswald, James Rounds
Research Collection Lee Kong Chian School Of Business
Measuring person–occupation fit serves many important purposes, from helping young people explore majors and careers to helping jobseekers assess fit with available jobs. However, most existing fit measures are limited in that they focus on single individual difference domains without considering how fit may differ across multiple domains. For example, a jobseeker might be highly interested in a job, yet not possess the requisite skills or knowledge to perform the job well. The current research addresses this issue by evaluating an integrative set of person–occupation fit assessments that measure 88 fit dimensions across five domains: vocational interests, work values, knowledge, …
An Analysis Of Cellular And Tissue Function Of Lipin In Drosophila Melanogaster, Judah Christian Scott
An Analysis Of Cellular And Tissue Function Of Lipin In Drosophila Melanogaster, Judah Christian Scott
Graduate Theses and Dissertations
Regulation of energy expenditure and energy storage is a key characteristic of life. Numerous enzymes play a crucial role in regulating energy metabolism. Lipins are a highly conserved family of proteins that function in both lipid synthesis and gene regulation. In the glycerol-3 phosphate pathway, lipins act as a phosphatidate phosphatase (PAP) producing diacylglycerol. In gene regulation, lipins act as transcriptional co-regulators of metabolic genes. The enzymatic PAP activity occurs in the cytoplasm; however, for lipins to function as gene regulators, they must translocate into the nucleus. Nuclear translocation is facilitated by the nuclear localization signal (NLS) within the protein. …
Bacterial Chondronecrosis With Osteomyelitis In Broilers: Etiology And Selected Mitigation Measures, Khawla Saud Alharbi
Bacterial Chondronecrosis With Osteomyelitis In Broilers: Etiology And Selected Mitigation Measures, Khawla Saud Alharbi
Graduate Theses and Dissertations
Bacterial chondronecrosis with osteomyelitis (BCO) is the predominant cause of lameness in broiler chickens. It mainly impacts broiler production and animal welfare, causing substantial financial losses accounting for 1- 2% due to bird condemnations at the marketing age. Remediating BCO lameness disease demands investigating its causes using appropriate models and evaluating preventive measures, such as enhancing epithelial tissue health and tight junction integrity in the digestive and respiratory tract, strengthening immune functions, and improving bone strength. Therefore, the objectives of this dissertation were to 1) study predisposing factors for BCO lameness by investigating the effects of deoxynivalenol (DON) and fumonisin …
Fungi To Form: Exploring Mushroom Mycelium As A Bio-Material For Zero-Waste Interior Furnishings And Forms, Drew M. Gobbi
Fungi To Form: Exploring Mushroom Mycelium As A Bio-Material For Zero-Waste Interior Furnishings And Forms, Drew M. Gobbi
Interior Design Undergraduate Honors Theses
This capstone explores new applications for mycelium, the root structure of mushrooms, in the architecture and interior design industry. Due to its naturally renewable and 100% compostable nature, mycelium proves itself to be a highly sustainable material. Through a combination of research, analysis, and hands-on experimentation, both the challenges and possibilities of mycelium are documented and defined in the context of solutions for fast-furniture waste, a phenomenon that includes mass-produced, low-cost items designed for short-term use. Following a foundation of literature reviews and case studies, this paper documents small-scale prototyping of mycelium-based models for the Ground-Up Chair, a simple yet …
Experiential Advertising: The Immersive Evolution Of Marketing, Julianna Ferguson
Experiential Advertising: The Immersive Evolution Of Marketing, Julianna Ferguson
Interior Design Undergraduate Honors Theses
Experiential advertising is revolutionizing marketing by creating immersive, emotionally resonant brand environments that foster consumer engagement and loyalty. This thesis explores the integration of experiential design in commercial branding, emphasizing how sensory-driven storytelling enhances brand identity and consumer connections. Through case studies such as the Gucci Garden in Florence, this research highlights the effectiveness of flagship stores, pop-ups, and sensory campaigns in transcending traditional advertising methods. Employing firsthand observations and analytical frameworks, the study identifies critical design strategies, including interactive installations and curated spaces, that reshape retail environments into platforms for emotional connection and advocacy. Findings reveal that experiential design …
Social Identity And Eating Behaviors: How Cultural Norms Impact Disordered Eating, Cierrah J. Fulenwider
Social Identity And Eating Behaviors: How Cultural Norms Impact Disordered Eating, Cierrah J. Fulenwider
Electronic Theses and Dissertations
Disordered eating behaviors (DEBs), such as frequent dieting, emotional eating, and obsessive “clean eating,” are increasingly prevalent in our society and have been linked to significant physical and psychological health risks. However, the role of sociocultural influences, such as discrimination and social media, are often overlooked. This study examined the relationship between disordered eating behaviors and perceived discriminatory experiences, social media use, physical self-description, and attitudes toward eating among undergraduate college students. The sample consisted of 110 undergraduate students. Participants completed an electronic survey comprised of the Everyday Discrimination Scale-S (EDS-S), Social Media Usage Scale (SMUS), Eating Attitudes Test-26 (EAT-26), …
Longing For The Prodigal: Nonviolent Communication And The Journey From Estrangement To Understanding, Amelia D. Little
Longing For The Prodigal: Nonviolent Communication And The Journey From Estrangement To Understanding, Amelia D. Little
Electronic Theses and Dissertations
This study explores how parents who practice nonviolent communication (NVC) navigate conflict with their adult children, offering insights into how collaborative conflict resolution can transform intergenerational relationships. Drawing on family systems theory and sanctification theory, this qualitative study examines how parents shift from coercive and avoidant conflict strategies to become more empathetic and collaborative. Semi-structured interviews with ten NVC-practicing parents demonstrate that NVC extends traditional conflict styles theory (Kilmann & Thomas, 1978) by emphasizing emotional awareness as essential components of effective collaboration. Additionally, narrative analysis highlights how family storytelling reframes past conflicts, fostering relational healing. The study contributes to family …
Sacred Connections In Cartoonish Places: Exploring The Implications Of Teotl In Avatar: The Last Airbender (2008), Makenzie P. Morrison
Sacred Connections In Cartoonish Places: Exploring The Implications Of Teotl In Avatar: The Last Airbender (2008), Makenzie P. Morrison
Electronic Theses and Dissertations
Taking Avatar: The Last Airbender (2008) seriously, Sacred Connections in Cartoonish Places explores the animated children’s series and how it is understood through the monistic Nahua (Aztec) concept of teotl. Relying on James Maffie’s text Aztec Philosophy: Understanding a World in Motion (2014), this thesis determines that Avatar: The Last Airbender benefits from monistic analysis. This analysis results in a breakdown of the show into four body chapters. These chapters respectively explore Aang’s role as a monistic representative, the differences between the physical and spirit worlds presented in the show, the kind of relationships that appear in the series, and …
Antiracist Expert Evidence, Jasmine Gonzales Rose, Asees Bhasin, Spencer Piston
Antiracist Expert Evidence, Jasmine Gonzales Rose, Asees Bhasin, Spencer Piston
Faculty Scholarship
Since 2020, when mass protests against racism swept across the United States, scholars, lawyers, and the general public have become increasingly aware that racism permeates society and the criminal legal system, from overt racial animus to the nuanced effects of structural racism. Demonstrating the influence of racism is therefore vital to the practice of criminal defense, yet many attorneys do not know how to prove racism in court. We surveyed over seven hundred criminal-defense attorneys across the United States, and nearly half had never heard of expert witnesses testifying or submitting written reports on racism—what we call “antiracist expert evidence.” …
Do Bans On Conversion Therapy Impose A Governmental "Orthodoxy" About Sex And Gender?, Linda C. Mcclain
Do Bans On Conversion Therapy Impose A Governmental "Orthodoxy" About Sex And Gender?, Linda C. Mcclain
Faculty Scholarship
In Part I, this Essay evaluates how orthodoxy arguments featured in Mr. Tingley’s challenge to Washington’s ban on conversion therapy. Part II offers a preliminary analysis of Chiles v. Salazar, 42 which the Court will hear during its 2025-2026 Term. I illustrate how the arguments made against Washington’s law by Chiles and her amici draw from the anti-orthodoxy and marketplace of ideas rhetoric found not only in Justice Thomas’s Tingley dissent and his NIFLA opinion but also in Justice Gorsuch’s majority opinion in the 303 Creative decision.43 Woven together with these speech arguments are appeals to the Court’s …
Examination Of The Relationships Between Religious Or Atheistic Belief Certainty And Mental Health Outcomes, Christopher S. Percifield
Examination Of The Relationships Between Religious Or Atheistic Belief Certainty And Mental Health Outcomes, Christopher S. Percifield
All-Inclusive List of Electronic Theses and Dissertations
Perceived meaning in life is considered to be an outcome of one’s efforts to create and sustain a sense of subjective understanding and purpose in the world. Meaning-making researchers have historically emphasized the role of religious worldviews as fundamental structures through which meaning-making attempts can be guided. Often, researchers have suggested that religious beliefs offer unique benefits for physical and psychological well-being for religious believers compared to non-believers. Archival data was analyzed across two separate waves, and significant correlates of aspects of meaning in life, belief certainty, and psychological well-being were identified. Perceived meaning and peace and mitigation of lapses …
Stories In Style: Interactive Fashion Exhibits As Tools For Activating Special Collections, Riley Mason
Stories In Style: Interactive Fashion Exhibits As Tools For Activating Special Collections, Riley Mason
Theses
Interpretation is a museum’s most significant form of communication with visitors. Historic collections, material representations of distinct historical narratives and themes, hold objects and cultural knowledge that enable them to contextualize contemporary concepts like fashion through exhibit-based interpretation and extend these concepts beyond labels through interactivity. To investigate the role of these specialized repositories in challenging existing narratives and connecting with modern audiences, this thesis developed a collection-driven exhibit to answer the following question: how can institutions activate special collection objects through relevant interpretation and non-digital interactive experiences in exhibits? Through researching and analyzing four objects from the Bruce and …
Rooted In Ogdensburg: A Creative Exhibition From Classroom To Gallery, Finn Bishop-Duford
Rooted In Ogdensburg: A Creative Exhibition From Classroom To Gallery, Finn Bishop-Duford
Theses
Picture this: you are an elementary student- wandering around an art exhibition. On the wall hangs artwork you dedicated your time to. How does it make you feel? Art exhibitions of student work are a display practice implemented at the James F. Montpelier Gallery located at Ogdensburg Free Academy in Ogdensburg, New York. Such student-focused art exhibitions, historically, create a wonderful, inspirational, and impactful environment for students to display their finest works. Once the COVID-19 pandemic hit the world by storm in 2020, the thematic shows shifted to assemblages of students’ best work. This is due to the limited time …
Bioinformatics-Guided Identification And Quantification Of Biomarkers Of Crotalus Atrox Envenoming And Its Neutralization By Antivenom, Auwal A. Bala, Anas Bedraoui, Salim El Mejjad, Nicholas K. Willard, Joseph D. Hatcher, Anton Iliuk, Joanne E. Curran, Elda E. Sanchez, Montamas Suntravat, Emelyn Salazar, Rachid El Fatimy, Tariq Daouda, Jacob Galan
Bioinformatics-Guided Identification And Quantification Of Biomarkers Of Crotalus Atrox Envenoming And Its Neutralization By Antivenom, Auwal A. Bala, Anas Bedraoui, Salim El Mejjad, Nicholas K. Willard, Joseph D. Hatcher, Anton Iliuk, Joanne E. Curran, Elda E. Sanchez, Montamas Suntravat, Emelyn Salazar, Rachid El Fatimy, Tariq Daouda, Jacob Galan
School of Medicine Publications
Quantitative mass spectrometry-based proteomics of extracellular vesicles (EVs) provides systems-level exploration for the analysis of snakebite envenoming (SBE) as the venom progresses, causing injuries such as hemorrhage, trauma, and death. Predicting EV biomarkers has become an essential aspect of this process, offering an avenue to explore the specific pathophysiological changes that occur after envenoming. As new omics approaches emerge to advance our understanding of SBE, further bioinformatics analyses are warranted to incorporate the use of antivenom or other therapeutics to observe their global impact on various biological processes. Herein, we used an in vivo BALB/c mouse model and proteomics approach …
Achieving Fairness In Zoning Laws With Machine Learning, William Schimitsch
Achieving Fairness In Zoning Laws With Machine Learning, William Schimitsch
College Honors Program
Zoning is a powerful regulatory tool that determines how municipalities use and develop land. The goal of zoning is to classify land use (e.g., residential, commercial, industrial) to maximize compatibility among neighboring parcels. Local zoning decisions, however, are made by small-sized boards, often through an opaque process, which raises concerns about bias and fairness. In the United States, zoning has historically prioritized single-family housing and thus created economic barriers that limit access to certain communities. Given the task of classifying land use and the wealth of geographical, demographic, and infrastructural data describing each parcel, the problem of bias in zoning …
Empowering Dreams: The Massachusetts Tuition Equity Law And Its Impact On Undocumented Latine Students, Belén Zúñiga, Melissa Colón
Empowering Dreams: The Massachusetts Tuition Equity Law And Its Impact On Undocumented Latine Students, Belén Zúñiga, Melissa Colón
Gastón Institute Publications
As a result of the Tuition Equity Law enacted in September 2023, Massachusetts is one of 25 states1 that have encouraged access to higher education for non-citizens, including undocumented students2 (Broder and Kmec, 2024). Under the Tuition Equity Law, undocumented students, who: attended a high school (9th-12th grade)3 in Massachusetts with any combination of three years, graduated from a Massachusetts high school or have a Massachusetts high school diploma equivalent (GED/HiSet), and are admitted to a public institution of higher education in Massachusetts, can attend at in-state tuition rates (Massachusetts Department of Higher Education, 2023). They are also eligible to …
Effects Of Environmentally Relevant Concentrations Of Roundup On Oxidative-Nitrative Stress, Cellular Apoptosis, Prooxidant-Antioxidant Homeostasis, Renin And Cyp1a Expressions In Goldfish: Molecular Mechanisms Underlying Kidney Damage During Roundup Exposure, Md Imran Noor, Md Saydur Rahman
Effects Of Environmentally Relevant Concentrations Of Roundup On Oxidative-Nitrative Stress, Cellular Apoptosis, Prooxidant-Antioxidant Homeostasis, Renin And Cyp1a Expressions In Goldfish: Molecular Mechanisms Underlying Kidney Damage During Roundup Exposure, Md Imran Noor, Md Saydur Rahman
School of Earth, Environmental, & Marine Sciences Faculty Publications
Roundup is one of the most widely used glyphosate-based harmful herbicides in the United States as well as globally, which poses a severe risk for terrestrial and aquatic organisms. In order to identify the detrimental effects of Roundup exposure in aquatic organisms, we investigated the environmentally relevant concentrations of Roundup exposure (low dose: 0.5 μg/L and high dose: 5.0 μg/L for 2 weeks) on renin expression, oxidative-nitrative stress biomarkers (e.g., 2,4-dinitrophenol, DNP; and 3-nitrotyrosine protein, NTP), prooxidant-antioxidant enzymes expressions (e.g., superoxide dismutase, SOD; and catalase, CAT), cellular apoptosis, and cytochrome P450 1A (CYP1A) mRNA levels in the kidneys of goldfish …
Microplastics In Coastal And Marine Environments: A Critical Issue Of Plastic Pollution On Marine Organisms, Seafood Contaminations, And Human Health Implications, Rebecca Muñiz, Md. Saydur Rahman
Microplastics In Coastal And Marine Environments: A Critical Issue Of Plastic Pollution On Marine Organisms, Seafood Contaminations, And Human Health Implications, Rebecca Muñiz, Md. Saydur Rahman
School of Earth, Environmental, & Marine Sciences Faculty Publications
Plastic has quickly become one of the world's most prevalent environmental pollutants. Population growth has only amplified the demand, resulting in 430 million tons of plastic produced annually, with 11 million tons ending up in our oceans. Without intentional intervention, plastic waste in the oceans is expected to triple, posing severe risks for the aquatic ecosystems, animals, and humans dependent on these waters. As plastic accumulates in oceans and other water environments, the non-biodegradable particles break down into micro- and nano-plastics, invading coastal and marine organisms and causing considerable physiological and morphological damage. This is especially concerning for the millions …
Scar Reveal, Danielle A. Unger
Scar Reveal, Danielle A. Unger
LSU New Orleans Theses and Dissertations
Scar Reveal is a collection of twenty-eight poems. The author arranges the poems in three sections that explore the family of origin and religion, mental health and mortality, and love and labor. The collection is preceded by a preface essay where the author discusses her relationship with poetry and how her poetics have developed throughout her mental health recovery and work as a therapist. The author also provides a brief overview of some selected craft techniques and influences within the manuscript.
More Concerns About Atmospheric Methane Removal Efforts, Joshua Luczak
More Concerns About Atmospheric Methane Removal Efforts, Joshua Luczak
Research Collection College of Integrative Studies
The National Oceanic and Atmospheric Administration reported record-high global atmospheric carbon dioxide levels (419.3 ppm) in 2023, alongside atmospheric methane levels (1922.6 ppb) now over 160% above pre-industrial levels. The World Meteorological Organization predicts 2024 could surpass 2023 as the warmest year on record, with more frequent and severe extreme weather events. Meeting the Paris Climate goal of limiting global warming to well below 2°C—or ideally 1.5°C—above pre-industrial levels is becoming increasingly difficult. To address these challenges, efforts are expanding beyond reducing greenhouse gas emissions. While carbon dioxide removal (CDR) technologies have been the focus, attention is now turning to …
Pilot Testing An Ecotherapy Program For Adolescence: Initial Findings And Methodological Reflections, Sophie Westwood, Grace Edmunds-Jones, Thomas Maguire, Sue Hawley, Hannah Avent, Jerry Griffiths, Rishi Bates, Jane Marley, Gary Wallace, Ruth Harrell, Sheena Asthana, Felix Gradinger
Pilot Testing An Ecotherapy Program For Adolescence: Initial Findings And Methodological Reflections, Sophie Westwood, Grace Edmunds-Jones, Thomas Maguire, Sue Hawley, Hannah Avent, Jerry Griffiths, Rishi Bates, Jane Marley, Gary Wallace, Ruth Harrell, Sheena Asthana, Felix Gradinger
Peninsula Medical School
Children and young people’s mental health and well-being has seen a dramatic decline. In the UK, this has been exacerbated by service retrenchment associated with austerity, with evidence of increasing health inequalities. Service innovation that is grounded in practice, has ongoing learning, and is co-designed with children and young people is required now. This can provide creative solutions within the local context and contribute to the fledgling evidence base that explores complex mechanisms of impact. This methodological reflection describes a co-design process of a bespoke, group-based ecotherapy programme: from early piloting using appreciative enquiry before COVID-19 by the mental health, …
Factors Influencing Community Assembly Of The Amphibian Microbiome In Rochester, Ny, Thomas R. Minahan
Factors Influencing Community Assembly Of The Amphibian Microbiome In Rochester, Ny, Thomas R. Minahan
Theses
Amphibians are crucial in wetlands and, by extension, our planet. As predator and prey, amphibians serve as keystone species, vital for the continued equilibrium in their wetland ecosystems. However, the global amphibian population is currently threatened by the spread of a pathogenic fungus known as Batrachochytrium dendrobatidis (Bd). Over the past thirty years, Bd has spread worldwide, threatening hundreds of amphibian species. The environmental factors that influence microbial community assembly in amphibians are key to developing interventions that can protect amphibians from disease. This research examines the abiotic and biotic factors influencing microbial community composition in amphibians of Rochester, New …
Bodies Unseen: Hysteria’S Stain On Women’S Healthcare, Layla Dehrab
Bodies Unseen: Hysteria’S Stain On Women’S Healthcare, Layla Dehrab
Theses
Bodies Unseen is a 5-minute motion graphics piece accompanied by a 12-page zine that explores the historical and ongoing dismissal of women’s pain within the medical system, rooted in the legacy of hysteria. Through the fictionalized stories of Ada, Rosa, and Mabel-women from different time periods who face misdiagnosis and neglect, the project illustrates the persistent gender bias in healthcare. Drawing from historical records, feminist theory, and contemporary research on medical inequity, this work connects past injustices to modern-day disparities in diagnosis and treatment. The animation and zine work in tandem to educate viewers and encourage dialogue about the systemic …
What’S Coco Eating Today: Using Fragmented Time To Reduce Stress, Yaxuan Wang
What’S Coco Eating Today: Using Fragmented Time To Reduce Stress, Yaxuan Wang
Theses
In modern society, electronic mobile devices have become an integral part of life and entertainment. From a developmental perspective, the abundance of virtual content has brought significant changes in emotional, cognitive, and social aspects. On this background, the rise of the gaming industry has made 'digital games' a common form of entertainment. As games become a normalized part of daily life, the variety of game types has expanded greatly. This led me to consider: through interaction design and using games as a medium, is it possible to reduce users' stress in a short time and provide positive emotional feedback? Based …
Ai Emotional Companion App, Ruyi Liu
Ai Emotional Companion App, Ruyi Liu
Theses
"Lumi" is an AI emotional companion app designed to provide personalized, immersive, and emotionally supportive experiences. The project explores how customizable virtual characters can fulfill the growing emotional and social needs of users through multimodal interaction, intimacy-building systems, and gamified engagement. By combining user interviews, competitive analysis, and iterative prototyping, this thesis investigates how design strategies can strengthen the user’s emotional bond with an AI character. The final product presents a flexible platform where users can create unique AI companions, interact in diverse ways, and develop lasting emotional connections. This work contributes to the field of emotional UX and digital …
A Remote Sensing-Based Evaluation Of Road And Electricity Infrastructure Expansion Effects On Development In Sub-Saharan Africa, Tunmise Ibukun Raji
A Remote Sensing-Based Evaluation Of Road And Electricity Infrastructure Expansion Effects On Development In Sub-Saharan Africa, Tunmise Ibukun Raji
Theses
Sub-Saharan African countries consistently rank low on human development indicators despite decades of international aid and domestic investment. To address these challenges, governments across the region are allocating substantial portions of their national budgets to infrastructure expansion, viewing it as a catalyst for accelerated socio-economic development. However, given severely constrained budgets, these nations often face trade-offs between infrastructure development and investment in other important sectors such as healthcare and education. This highlights the need for infrastructure investments to deliver their anticipated benefits. This dissertation examines the relationship between infrastructure development and socio-economic development in Sub-Saharan Africa, with a particular focus …