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The Correlation Between Zinc Intake And Superoxide Dismutase Activity With Cognitive Function In The Elderly, Rima Khuzaimah, Fiastuti Witjaksono, Novi Silvia Hardiany

Sultan Qaboos University Medical Journal

Objectives: This study aimed to analyse the correlation between zinc intake and superoxide dismutase (SOD) with cognitive function in the elderly. Thus, the role of zinc as a structural component of SOD, along with SOD’s contribution to cognitive function, can be established. Methods: This cross-sectional study was conducted at Panti Sosial Tresna Wredha Budi Mulia 1 in Jakarta, Indonesia, from July to September 2024. Elderly men and women were included. Zinc intake was assessed using the Semi-Quantitative Food Frequency Questionnaire, while plasma SOD activity was measured by spectrophotometer. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesia version. Data …

Small But Mighty: Precision Dairy Health Monitoring With Sensor Technology, Nicholas Gosling

UNH Today Archive

No abstract provided.

Runx2 Is Essential For Maintaining Synchondrosis Chondrocytes And Cranial Base Growth, Shawn A Hallett, Ashley Dixon, Isabella Marrale, Lena Batoon, José Brenes, Annabelle Zhou, Ariel Arbiv, Vesa Kaartinen, Benjamin Allen, Wanida Ono, Renny T Franceschi, Noriaki Ono

Faculty, Staff and Student Publications

The cranial base synchondroses, comprised of opposite-facing bidirectional chondrocyte layers, drive anteroposterior cranial base growth. In humans, RUNX2 haploinsufficiency causes cleidocranial dysplasia associated with deficient midfacial growth. However, how RUNX2 regulates chondrocytes in the cranial base synchondroses remains unknown. To address this, we inactivated Runx2 in postnatal synchondrosis chondrocytes using a tamoxifen-inducible Fgfr3-creER (Fgfr3-Runx2cKO) mouse model. Fgfr3-Runx2cKO mice displayed skeletal dwarfism and reduced anteroposterior cranial base growth associated with premature synchondrosis ossification due to impaired chondrocyte proliferation, accelerated hypertrophy, apoptosis, and osteoclast-mediated cartilage resorption. Lineage tracing reveals that Runx2-deficient Fgfr3+ cells failed to differentiate into osteoblasts. Notably, Runx2-deficient chondrocytes showed …

Assessing Consumer Perceptions And Attitudes Towards Cultured Meat Using X (Twitter) Data: Implications For Decision Support, Guoste Pivoraite, Shaofeng Liu, Saeyeon Roh, Guoqing Zhao

Plymouth Business School

Cultured meat (CM) is considered to have a potential to address environmental, sustainability, ethical concerns, and food security, however, consumer acceptance remains a challenge. This study empirically validatesand extends the Cultured Meat Attitude and Perception Assessment (CAPA) model by analysing public discussions on X (Twitter) to understand consumer perceptions of CM. Using BERTopic for topic modelling and qualitative analysis, the study explored unprompted public narratives, mapping them to CAPA constructs to examine how public opinions align with or challenge existing theoretical concepts. The findings revealed a combination of cultural, political, ethical, and economic narratives shaping consumer behaviour and theirdecision-making processes …

We Didn’T Start The Fire: For And Against Koppelman On The Corruption Of Libertarianism, Roderick T. Long

The Journal of Contemporary Legal Issues

At the philosophic core of libertarianism is a set of market-oriented commitments that are entirely compatible with, and indeed congenial to, traditional leftist concerns with the well-being of the disadvantaged in society. But over the past several decades, the libertarian movement has fallen increasingly under the spell of toxic, callous, right-wing versions of libertarianism that scorn empathy while championing the cause of the economic winners in society at the expense of those who lose out.

That’s one way of stating the central thesis of Andrew Koppelman’s book Burning Down the House. And that thesis, so stated, is one I …

Notes From A Serf, Rachel Lu

The Journal of Contemporary Legal Issues

F. A. Hayek would have hated Obamacare. This must be distinctly understood, or nothing wonderful can come of the argument I am going to relate.

Burning Questions: A Response To Fishkin, Long, Lu, Mack, And Vallier, Andrew Koppelman

The Journal of Contemporary Legal Issues

I’m indebted to Larry Alexander and Steve Smith for organizing this conference, and to Joseph Fishkin, Roderick Long, Rachel Lu, Eric Mack, and Kevin Vallier for their thoughtful responses to my book, Burning Down the House: How Libertarian Philosophy Was Corrupted by Delusion and Greed. When San Diego organized this conference, I gave them the names of the people whom I was most eager to engage with, scholars I admire despite some deep disagreements. They have forced me to sharpen my own views. I am very lucky.

Hermeneutic Theory And The Priority Of Constitutional Meaning, Tyler S. Moore

The Journal of Contemporary Legal Issues

Can the understanding of a law be separated from its application? Despite the increasing convergence between schools of constitutional interpretation in the United States, this question remains central. One the one side are so-called “new originalists” for whom the distinction between understanding and application (or “interpretation” and “construction” as they call it) is necessary to separate a more objective step in the interpretive process from a more subjective one. On the other are “living constitutionalists,” many of whom suggest that defining a neat boundary between these two stages is impossible. When judges decide cases, they do not (and perhaps cannot) …

Warming A Calf, Cheyenne Reid, Reganne K. Briggs, Melanie Heaton, Rebekah Esplin, David Secrist

All Current Publications

Calves born in the winter or spring are often exposed to harsh weather and environmental conditions. After birth, calves may become chilled due to cold temperatures or not being dried off promptly. A chilled calf may be experiencing hypothermia. This fact sheet explains the different types of hypothermia and methods for warming a calf until it can be safely returned outside.

Tube-Feeding A Calf, Cheyenne Reid, Reganne K. Briggs, Melanie Heaton, Rebekah Esplin, David Secrist

All Current Publications

Producers may need to tube-feed a newborn calf to provide milk if calves are unable to nurse or suck from the nipple bottle or when calves are sick and need electrolytes. This fact sheet outlines the materials required and the steps to successfully tube-feed a calf.

Dynamic Rendering Of Views Of Geographic Data With Generative Ai For Seasonal And Temporal Variations, Joseph Edwin Johnson Jr., Quinn Thuy Johnson

Defensive Publications Series

Current mapping systems present geographic data, such as satellite imagery and 3D map layers, in a static manner, limiting the user's ability to visualize environmental changes over time. This disclosure describes a system and technique that leverages generative artificial intelligence (GenAI) and neural radiance fields (NeRF) to dynamically render geographic data, simulating seasonal and temporal variations. This approach transforms map data based on user prompts or inferred seasonal/temporal data and enables novel viewpoint generation and animation of 3D map views. The system enhances realism, provides a more informative user experience, and has applications in various fields, including navigation, urban planning, …

Disguising Emotional Distress Damages: Why Permitting Recovery Of “Reasonable And Necessary” Veterinarian Expenses Creates Inconsistency In Virginia, Ethan Payne

Liberty University Law Review

Humans crave companionship. This companionship comes first from a relationship with God and second from an inferior yet ordained relationship with other humans. But what about the creatures not made in God’s image? What about the previously wild creatures we bring into our homes as pets? Many cherish these animals with a love akin to family, especially dogs and cats. But is this the proper pedestal for pets?

This is an ongoing struggle humans have debated since as far back as dogs and cats have been domesticated. As time progressed, select cultures of various geographical backgrounds have subjugated animals, using …

Agent-Based Modeling: Introduction And Actuarial Applications, Rick Gorvett

Mathematics and Economics Faculty Working Papers

Agent-based modeling (ABM) has become an important and valued approach to modeling complex systems. In this paper, I advocate for actuaries to recognize the complex systems-nature of socioeconomic and risk processes and for ABM models to become a regular resource in our actuarial toolkits. These models allow for the observation of potential macro-behavior emerging from the underlying agent-level micro-activity and characteristics. Therefore, ABM models can provide significant insight into the quantification of risk and the identification of optimal strategies. This paper is an introduction and guide to ABM models, and it includes several case studies to illustrate their utility.

The Role Of G6pd Variants And 3d Genomic Structure In The Development Of Pulmonary Hypertension, Christina M. Signoretti Ph.D.

NYMC Student Theses and Dissertations

Pulmonary hypertension is an under-recognized global health epidemic which is estimated to affect 1% of the population. It is associated with sustained mean pulmonary artery pressure greater than 20 mmHg, pulmonary artery remodeling, smooth muscle and endothelial cell proliferation and subsequent increased right ventricle hypertrophy due to increased afterload. Glucose-6-phosphate dehydrogenase (G6PD) is one of the key enzymes in the pentose phosphate pathway and has been previously linked to the development of pulmonary hypertension. G6PD deficiency is the most common human enzymopathy which affects approximately 400 million people worldwide and is a result of agricultural and epidemiological evolution in different …

Mechanisms Of Placental Impairment And The Upregulation Of Fetuin-B During Maternal Undernourishment, Mia Camilliere

NYMC Student Theses and Dissertations

Proper nutrition is crucial during pregnancy to support fetal and placental development. Failure to meet these nutritional needs can result in adverse health outcomes for both mother and baby. Despite its high prevalence in underdeveloped countries, maternal undernourishment is a public health issue worldwide. There are several possible causes of maternal undernourishment, and these can occur alone or in combination, such as poor access to nutrition, hyperemesis gravidarum, and drug use. This condition can adversely affect placental development and function to the extent of placental insufficiency, perturbing the entire pregnancy. The placenta is responsible not only for hormonally and physically …

Adaptation And Discovery In The Ethiopian Highlands: Testing Rules, Cryptic Shrews, And Patterns Of Montane Mammal Diversity, Evan W. Craig

Graduate Doctoral Dissertations

Montane landscapes of the Horn of Africa harbor exceptional but incompletely documented biodiversity. Focusing on rodents and shrews—the dominant but least studied of Ethiopia’s high-elevation fauna—this dissertation integrates repeat faunal surveys, genomic taxonomy, and phylogenetically informed modelling to clarify how small mammals distribute, diversify, and morphologically adapt across steep elevational gradients.

A century‐scale resurvey of Simien Mountains National Park (1927-2015) revealed significant upward range shifts for multiple species and a persistent mid-elevation richness peak, implicating warming temperatures as a driver of community reassembly. Museomics using genome-skimming and craniodental morphometrics subsequently uncovered a deeply divergent miniature shrew lineage within the Crocidura …

The Effects Of Morphine, Thc, And Lsd On Synaptic Plasticity Of The Ventral Tegmental Area, Michael Von Gunten

Theses and Dissertations

The brain is an intricate network of neurons that communicate via synapses. Synaptic plasticity, which is the ability to strengthen or weaken synaptic connections, plays a key role in learning, memory, and reward learning. Disruptions to synaptic plasticity play a central role in addiction, particularly in brain circuits involved in reward and motivation. The mesolimbic reward system, which includes the ventral tegmental area (VTA) and its dopaminergic projections, is a primary target of drugs of abuse, including opioids and cannabinoids. However, the physiological consequences of combined exposure to opioids and cannabinoids and the potential for psychedelics to reverse drug-induced neuroadaptations …

Uhsp Master Of Public Health Student Handbook 2025-2026

Handbooks

No abstract provided.

Bellyache, Valerie Braylovskiy

Canterbury Scholars

My manuscript of poems, called "Bellyache," speaks to my experience with endometriosis and how it intersects with both womanhood, and the pain we inherit from our ancestors that becomes stored in our bodies over time. This project gave me the permission to write poems that grapple with both escaping and recreating what it’s like to be a woman inside the medical system which continues to equate pain with hysteria, and inside a world that either says you’re sick, or you aren’t.

Cardiac Amyloid, The Great Imitator, Nolan R. Fox, Nicholas J. Fox, Emily Newman, Brian Osler, Eugene Storozynsky

Division of Cardiology Faculty Papers

BACKGROUND: Although endomyocardial biopsy (EMB) is the criterion standard for diagnosis of infiltrative cardiac disease, cardiac sarcoidosis (CS) or cardiac amyloid can be diagnosed noninvasively through both clinical suspicion and advanced imaging techniques of cardiac magnetic resonance imaging (CMR) or cardiac positron emission tomography (PET).

CASE SUMMARY: A 79-year-old man with mediastinal sarcoidosis presented with new chest pain and a right bundle branch block, raising concern for CS. CMR and cardiac PET also supported the diagnosis of CS, but EMB ultimately revealed transthyretin amyloid cardiomyopathy. The patient was started on tafamidis and showed improvement at 1-year follow-up.

DISCUSSION: This case …

Good Faith, Bad Faith, And Ugly Tactics: Bad Faith In Modern Insurance Litigation, John M. Forbes

Mercer Law Review

This Article seeks to explain bad faith in insurance litigation. Its purpose is to provide a general overview of the cause of action, as well as outline some of the nuances which make bad faith difficult to litigate for all involved. In this Article, Part III will introduce the general idea of the cause of action and discuss some of its history. Part IV will discuss the mechanics, including: first and third-party claims, procedural prerequisites, the origins of a claim, whether insurers must pay a claim to avoid bad faith, assignment, damages, and summary judgment. Part V will explain why …

Fundamental Dimensions Of Law And Legal Education: Developing A Model Of A Modern Legal System And Its Application To The Transnational Dimensions Of Law, Mark L. Jones

Mercer Law Review

The present article is the fourth in a series of articles addressing the fundamental dimensions of law and lawyering and urging the reliberalization of U.S. legal education. It is largely an exercise in analytical jurisprudence. Parts I and II seek to provide an account of a modern legal system and legal evolution that combines and integrates my own fundamental dimensions of law taxonomy with the accounts of a legal system given by the legal philosopher H.L.A. Hart and the comparatist John Henry Merryman. The model of a modern legal system these Parts develop should be part of the cognitive equipment …

Expressing Sincere Gratitude In Writing: A Modest Step Towards Being A Better And More Effective Lawyer, Bret Rappaport

Mercer Law Review

In my antique desk, at the far back of the big hard-to-open drawer, sits a large brown envelope. The envelope holds about forty years’ worth of thank-you notes to me. Some from clients. Some from coworkers. Some from students. Why do I keep them? Maybe I will be able to answer that question by the time I finish writing this Article. As I write this Introduction, I’m not sure. I don’t specifically remember each card or letter, but a couple do come to mind. They do so with blazing clarity. One is from my high school English teacher, Mrs. Severns. …

The Pressure Points Of Professional Identity For Judges In The Modern Era, Charles Gardner Geyh

Mercer Law Review

The duties core to the professional identity of a judge are encapsulated in an ethical directive at the literal forefront of the Model Code of Judicial Conduct, some variation of which all state and federal judiciaries have adopted. Rule 1.2 provides that “[a] judge shall act at all times in a manner that promotes public confidence in the independence, integrity, and impartiality of the judiciary[.]” This directive implicates three challenges, or pressure points, relevant to a judge’s identity: 1) insofar as judges begin their legal careers as practicing lawyers, when they ascend the bench their professional identities must transition from …

The Routledge Handbook Of Cultural Ecosystem Services, Pamela D. Mcelwee, Karen E. Allen, Rachelle K. Gould, Minna Hsu, Jun He

Open Access Fund Publications

The Routledge Handbook of Cultural Ecosystem Services provides an overview of Cultural Ecosystem Services (CES), which are the nonmaterial aspects of benefits that people derive from nature. These diverse and multifaceted contributions can include experiences, capabilities, and identities, among others. The Handbook addresses how these CES are valued, how they reflect human–nonhuman relationships, and what roles they can play in improved human well-being, ecosystem management, and trajectories towards sustainability.

This Handbook presents a wide array of perspectives on the roles CES can play in understanding relationships to nature, and on how those relationships might translate into policy. The Handbook includes …

Spatiotemporal Calcium Signaling Patterns Underlying Opposing Effects Of Histamine And Tas2r Agonists In Airway Smooth Muscle, Stanley Conaway, Joshua Richard, Deepak A. Deshpande

Center for Translational Medicine Faculty Papers

Intracellular calcium (Ca²⁺) release via phospholipase C (PLC) following G-protein-coupled receptor (GPCR) activation is typically linked to membrane depolarization and airway smooth muscle (ASM) contraction. However, recent findings show that bitter taste receptor agonists, such as chloroquine (CQ), induce a paradoxical and potent relaxation response despite activating the Ca²⁺ signaling pathway. This relaxation has been hypothesized to be driven by a distinct compartmentalization of calcium ions toward the cellular periphery, subsequently leading to membrane hyperpolarization, in contrast to the contractile effects of histamine. In this study, we further investigate the spatiotemporal dynamics of Ca²⁺ signaling in …

From Epidemics To Experimental Treatments: Amphibian Mass Mortality Events And A Potential Treatment For Chytridiomycosis, Daniel Callahan

Graduate Masters Theses

Worldwide, amphibian populations have experienced dramatic declines due to a variety of threats. Among them, disease has been particularly deleterious and continues to impact populations. In the United States and Canada, the three leading causes of amphibian mass mortality events are ranavirosis, chytridiomycosis, and severe perkinsea infection, all caused by infectious pathogens. While research and policy have helped populations recover from these diseases, more work needs to be done to develop practical and efficient treatments for these infections. Of these three diseases, chytridiomycosis has had the most devastating effects on amphibian populations globally. Caused by the chytrid fungi Batrachochytrium dendrobatidis …

Loper Bright: Resurrecting Skidmore In A New Era, Bernard W. Bell

Seton Hall Law Review

No abstract provided.

Living In Action: A Critical Phenomenological Study Of School-Based Mental Health Counselors’ Engagement In Social Justice Practices, Kerry Whiterell

Graduate Doctoral Dissertations

This study argues that a problem facing school-based mental health counselors is that neither traditional counseling psychology practices nor the public educational system in the United States were designed to meet the needs of students experiencing intersectional oppression. This study therefore described and compared traditional counseling psychology theory and practices with that of liberation psychology, and outlined social justice frameworks that are applicable to school-based mental health counselors. The overarching research question for this study then asked, “What are the experiences of social justice-oriented mental health counselors who work within public schools in Massachusetts?” To answer this question, a critical …

Microplastic Production And Toxicity Of Marine Ropes On Nantucket Island, Massachusetts, Amelia Lawson

Graduate Masters Theses

Marine environments have been affected greatly over the last 50 years by anthropogenic marine waste, particularly plastic. Plastic waste in the oceans comes from many sectors, such as textiles, shipping, and the fishing industry. As plastic litter degrades, it produces microplastics, including five major forms: foam, films, fragments, beads, and fibers. Fibers are the most prevalent microplastic type and are often formed from marine ropes, which are frequently discarded or lost at sea. These ropes contribute to entanglement, ingestion hazards, and microplastic pollution. While the shedding of microplastic fibers from ropes during active use has been studied, much less is …