Digital Commons Network^™

Annual Comprehensive Financial Report, Tipton County, For The Year Ended June 30, 2025, Tennessee. Comptroller Of The Treasury.

Tennessee County Audit Reports

No abstract provided.

Do Poverty Traps Exist In Uganda? Household Level Evidence From Panel Data, Alex Aliga, Susan Kavuma, Oryema John Bosco

Tanzanian Economic Review

This study aimed at providing new evidence on the existence of poverty trap among Uganda’s households using Uganda National Panel data. Evidence of the existence of a poverty trap is fundamental in guiding the development of sound policies and interventions targeted to assist in pulling households out of poverty trap. Analysis was based on two sets of panel data comprising 8,122 households from 3 waves (2009/2010-2011/2012) and 12,199 households from 4 waves (2013/2014-2019/2020). Using the PCA constructed asset index approach based on a parametric regression model, we show that a poverty trap exists. This is revealed by the negative quartic …

Understanding The Complementarity And Substitutability Of Cooking Fuels In Developing Countries: Evidence From 2020/21 Tanzania National Panel Survey, Samwel Saimon Lwiza, Monica Sebastian Kauky

Tanzanian Economic Review

Increasing access to alternative energy sources in developing countries might be a potential for multiple energy consumption rather than switching from traditional to modern ones. This study aims to examine the complementarity and substitutability of cooking fuels and factors influencing households’ choices of such fuels in developing countries. Two categories of cooking energy were considered: traditional (dirty) fuels - firewood, charcoal and kerosene; and modern (cleaner) fuels - Liquefied Petroleum Gas (LPG) and electricity. Based on a nationally representative sample of 5,199 households from the Tanzania National Panel Survey (NPS) of 2020/21, results from a Multivariate Probit model indicate that …

Integration Of Mechanism-Driven Computational Modeling And Public Data Resources For Chemical Toxicity Assessment, Elena Chung

Theses and Dissertations

Regulatory toxicology depends primarily on animal testing, which limits throughput, mechanistic interpretability, and applicability to human-relevant endpoints. This dissertation presents computational approaches that integrate publicly available bioactivity data with machine learning to support chemical safety evaluation. Oral carcinogenicity was modeled using curated chemicals from the US Environmental Protection Agency’s Integrated Risk Information System (IRIS) and activity data from over 1,900 PubChem assays. Quantitative structure-activity relationship (QSAR) models trained on statistically prioritized assays demonstrated strong predictive performance and were applied to rank the carcinogenic potential of more than 16,000 compounds. Hepatotoxicity was evaluated using a hybrid modeling approach that combined structural …

Anti-Lung Cancer Activity Of The Herbal Medicinal Plant Cycas Revoluta, Mohammed Raheem Khraibet, Enas Jawad Kadhim

Hilla University College Journal For Medical Science

Background: Phytochemicals have demonstrated strong potential in cancer therapy, and several researchers became interested in evaluating the anti-cancer effects of Cycas revoluta, a plant in herbal medicine.

Objectives: The present study examined the anti-proliferative effect of the n-butanol fraction from Cycas revoluta root extract on A549 human lung adenocarcinoma cells.

Materials and Methods: The roots were defatted with n-hexane and then extracted. The reflux technique—Soxhlet extraction with 85% ethanol and 15% distilled water—was then used to obtain the crude extract of the root, which was subsequently fractionated using the solvents chloroform, ethyl acetate, and n-butanol, respectively. Cytotoxicity was evaluated …

A Pedagogical Analysis Of How Unprefixed Verbs Of Motion Are Presented In Instructional Materials For Beginner Russian Language Learners, Elena Petrova, Kris Lewis

Russian Language Journal

It is well-known that verbs of motion (VoM) are quite challenging for Russian language learners. We analyze four VoM-specific pedagogical materials (three textbooks and one mobile application) for their usefulness in supporting second language acquisition and the development of new thinking-for-speaking (TFS) patterns in beginner-level Russian language learners. Focusing on directionality, scaffolding, comprehensible input, the use of visuals, and communicative activities, we highlight how these materials lay a foundation for understanding VoM but are not sufficient for helping learners fully develop new TFS patterns. We pose recommendations for future research, teaching, learning, and materials development in the area of Russian …

Antibiofilm Activity Of Amylases Isolated From The Bacteria Associated With The Soft Coral Sarcophyton Trocheliophorum, Asmaa Marshoud Al Harbi, Mamdoh T Jamal, Sathianeson Satheesh

Journal of King Abdulaziz University: Marine Science

Amylases are one of the important enzymes with tremendous biotechnological applications. In this study, the amylase enzyme producing bacterial strains associated with the soft coral Sarcophyton trocheliophorum was isolated and identified. The amylases were produced in a specific growth medium and the stability was tested under different pH and temperature conditions. The crude amylases were tested for the antibiofilm activity against two biofilm-forming bacterial strains. The amylase enzyme extracted from two bacterial strains (KAU-AS1 and KAU-AS3) showed good activity in the antibiofilm activity assays. The amylases reduced the growth and attachment of the biofilm bacteria. Also, the amylase enzymes degraded …

Lifecycle Of Greater Wax Moth Galleria Mellonella (Lepidoptera: Pyralidae) And Its Control By Natural Products, Tahani A. Alzahrani, Hanan S. Alyahya, Shatha I. Alqurashi, Jazem A. Mahyoub

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

The great wax moth (Galleria mellonella) is a major pest that affects honeybee colonies, causing serious damage to the honeycomb and disrupting beekeeping operations. This paper aims to review the life cycle of this insect and the natural control strategies used to manage its populations. This paper examines the different stages of growth of the great wax moth, including the stages of eggs, larva, pupae, and adults. The life cycle of this insect depends largely on environmental conditions, especially temperature, humidity and food quality, in addition, this paper focuses on natural control strategies, such as the use of plant extracts …

Optimizing The Processing Temperature For Synthesis Of Silver Nanoparticles Within Cellulose-Wool Keratin Supramolecular Matrix Using Butylmethylimmidazolium Chloride Ionic Liquid, Ngesa E. Mushi

Tanzania Journal of Engineering and Technology (TJET)

To date, the synthesis of silver nanoparticles on the surface of cellulose and wool keratin biopolymer, while dissolved in ionic liquid, is attractive because of its biomedical potential. However, the optimal processing temperature for the nanoparticle formation is unclear. The previously reported temperature of approximately 120°C gives unpredictable results. The current study employs a combination of 50% cellulose and 50% keratin, along with 69 mg of silver chloride, in Butylmethylimidazolium Chloride BMImCl ionic liquid, using a single-pot process to produce a supramolecular film via non-derivatized mechanochemical interactions. The primary objective is to experimentally establish the processing temperature to achieve stable …

Targeting The Pi3k/Akt/Mtor Pathway In Hormone-Receptor Positive Breast Cancer: A New Frontier In Precision Therapy, Rina Mehra, Arjun Nair, Sneha Iyer, Karthik Raman, Meera Joshi

Muthanna Medical Journal

Background: Hormone receptor-positive (HR+) breast cancer represents the most common subtype among Indian women and is typically managed with endocrine therapies. However, resistance to such therapies-often driven by activation of the PI3K/AKT/mTOR signaling pathway-poses a significant clinical challenge and necessitates the development of targeted treatment strategies. Objective: This review aims to evaluate the molecular basis, therapeutic efficacy, safety profiles, and real-world applicability of PI3K/AKT/mTOR inhibitors in the management of HR+ breast cancer, with a focus on their relevance within the Indian healthcare landscape. Methods: A comprehensive narrative review was conducted by searching PubMed, Scopus, Web of Science, and Google Scholar …

Bayesian-Weighted Mendelian Randomization Reveals Sleep Apnea Syndrome Mediates The Bmi-Chronic Pain Link, Wenbao Shi, Jing Luo, Liu Yang, Dalin Chen, Yongqin Zhang, Jun Peng, Kurt Ruetzler, Manyun Sun, Hua Jin

Faculty, Staff and Student Publications

Background: Body mass index (BMI) has a complex association with a variety of chronic pain conditions, which may be influenced by sleep apnea syndrome (SAS). However, the role of SAS within the causal pathway linking BMI to chronic pain remains unconfirmed. This study explored whether and to what extent SAS serves as a mediator between BMI and chronic pain using Bayesian-weighted Mendelian randomization (BWMR) techniques.

Methods: This study utilized genome-wide association study (GWAS) summary data for BMI (N=461,460) and SAS (N=476,853; based on ICD-10 code diagnostic registries) from the IEU OpenGWAS database, along with chronic pain GWAS data (ICD-10 code-based …

Production And Characterization Of Biodiesel From Malapari Seed Oil (Pongamia Pinnata L.): Evaluation Of Quality Parameters Based On The Indonesian National Standard (Sni) 04-7182-2015, Desi Adriyanti Nina Taebenu, Ni Luh Arpiwi, Ida Ayu Astarini

Makara Journal of Science

This study produced biodiesel from Malapari seed oil (Pongamia pinnata L.) by optimizing the esterification and transesterification processes. The objectives of this study were to determine the sulfuric acid (H₂SO₄) catalyst concentration in the esterification reaction that can reduc the free fatty acid (FFA) content of the seed oil to ≤2%, analyze the oil to methanol molar ratio (i.e.,1:6, 1:9, and 1:12) and KOH concentration (i.e.,2%, 4%, and 6%) that will produce the highest biodiesel yield, and evaluate the quality of the produced biodiesel according to the Indonesian National Standar (SNI) 04-7182-2015. The research was …

Cox Communications, Inc. V. Sony Music Entertainment, No. 24-171 (U.S. June 30, 2025), Charles Duan

Amicus Briefs & Court Filings

Under the Copyright Act, “[a]nyone who violates any of the exclusive rights of the copyright owner . . . is an infringer of the copyright." 17 U.S.C. §501(a). This Court has also recognized two categories of secondary liability, which means liability for the copyright infringement of another. Those two categories are “contributory” liability and “vicarious” liability. Metro-Goldwyn-Mayer Studios Inc. v. Grokster, Ltd., 545 U. S. 913, 930. This case concerns contributory liability, which requires that a provider intended its service to be used for infringement. A copyright owner can show the requisite intent in two ways. First, it can show …

Effect Of Genotype On Herbivory And Growth Rate In Heliconia Stricta In A Common Garden Experiment In The Amazon, Xaali O’Reilly-Berkeley, Abhiraj Chakraborty, Javier L. Patiño Uyaguari, Hannah L. Mossman, Richard F. Preziosi, Jennifer K. Rowntree

School of Biological and Marine Sciences

Plant genotype is known to affect plant-invertebrate interactions. However, in megadiverse tropical habitats there has been relatively little exploration of the influence of the plant genotype on plant growth and biotic interactions in an experimental setting. We set-up three adjacent plots in rainforest at the foothills of the Andes (Orellana, Ecuador), where we planted clones of 37 individual Heliconia stricta rhizomes collected from up to 4 km away. Each rhizome was split into at least three individual pieces, resulting in three genetically identical replicates. At least one representative of each genotype was planted in each plot. Shoot height was measured …

Therapeutic Potential Of Bone Marrow-Derived Stem Cells In The Treatment Of Ewing Sarcoma: New Approach, Nasser Ghaly Yousif, Fadhil G. Alamran, Ahmed Altimimi

Muthanna Medical Journal

Background: Ewing Sarcoma is a challenging pediatric bone cancer with limited treatment options, particularly in advanced stages. Recent research has highlighted the potential of bone marrow-derived stem cells (BMSCs) as a novel therapeutic approach due to their tumor-targeting capabilities and ability to modulate the tumor microenvironment. Objective: This study aims to explore the therapeutic potential of BMSCs in the treatment of Ewing Sarcoma, focusing on innovative strategies that leverage their unique properties to enhance treatment efficacy and patient outcomes. Methods: This study involved a comprehensive review of the literature on BMSCs and their application in cancer therapy, …

Data Protection’S Function In Society: A Search For The Limits Of A Non-Absolute Right, Katherine Nolan

Research Outputs: 2025-Present

No abstract provided.

The Epilepsy Centers Of Excellence At The Veterans Health Administration, Zulfi Haneef, Caleb A Casanova, Vincent Zhang, Jennifer R Bonds King, Rizwana Rehman, Nina I Garga, Glenn D Graham, Alan R Towne

Faculty, Staff and Students Publications

Introduction: The Veterans Health Administration (VHA) Epilepsy Centers of Excellence (ECoE) was established in 2008 to provide specialized care for veterans with epilepsy. Although established more than a decade ago, there has been no systematic evaluation of the ECoE's performance in key mission areas. We evaluated their performance in several key mission areas-clinical care, research, education, and outreach-since inception to evaluate their success in meeting the initial mandate.

Materials and methods: We analyzed available data from relevant literature, ECoE annual reports, and the ECoE website between 2011 and 2023. Clinical care is the primary mission of the ECoE and was …

"Holy Cow, Where Do I Sign Up?" Attitudes Of Military Veterans Toward Epigenomic Biomarker Toxic Exposure Testing, Stacey Pereira, Calvin Apodaca, Kyle Slominski, Rachele K Lipsky, Cristian Coarfa, Cheryl L Walker, Amy L Mcguire, Lea Steele, Drew A Helmer

Center for Medical Ethics and Health Policy Staff Publications

Introduction: After the Sergeant First Class Heath Robinson Honoring Our Promise to Address Comprehensive Toxics Promise to Address Comprehensive Toxics (PACT) Act in 2022, there has been a great interest in studying toxic exposures encountered during military service. Development of epigenomic biomarkers for exposures could facilitate understanding of exposure-related health effects, but such testing could also provide unwanted information.

Materials and methods: We explored attitudes toward epigenomic biomarker research and the potential to test for past exposures using semistructured interviews with Veterans (n = 22) who experienced potentially harmful exposures.

Results: Twenty Veterans said they would hypothetically want to receive …

Lurasidone For Pediatric Bipolar Disorder: A Systematic Review, Alexia Koukopoulos, Claudia Calderoni, Georgios D Kotzalidis, Tommaso Callovini, Lorenzo Moccia, Silvia Montanari, Gianna Autullo, Alessio Simonetti, Mario Pinto, Giovanni Camardese, Gabriele Sani, Delfina Janiri

Faculty, Staff and Students Publications

Background/Objectives: Lurasidone ((3aR,4S,7R,7aS)-2-{(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylmethyl]cyclohexylmethyl}hexahydro-4,7-methano-2H-isoindole-1,3-dione) is a second-generation antipsychotic approved for schizophrenia and mood disorders. Adolescents and children with bipolar disorder receive treatments that expose them to weight gain and metabolic syndrome. Lurasidone is relatively free from such side effects, so it may constitute a useful alternative for the treatment of these patients. We focused on the use of lurasidone in children and adolescents with bipolar disorder.

Methods: On 11 June 2025, we used the following strategy on PubMed: lurasidone AND ("bipolar disorder" OR "bipolar depression" OR mania OR manic). We filtered for humans and ages 0-18 years and included …

The Enhanced Booklet Technique And Its Impact On Learning Outcomes In The Motor Education Course, Magdy Mahmoud Fahim Mohamed, Amira Mahmoud Taha Abdelrahim

Modern Sport

This study aims to examine the effect of enhanced Booklet Technique on the learning outcomes of the motor education course. The researchers adopted a quasi-experimental methodology employing a two-group post-test design, with one experimental and one control group. The sample, randomly selected, consisted of 120 first-year students from the Faculty of Physical Education at the University of Sadat City during the academic year 2023/2024, representing 16.74% of the total population. The participants were divided equally into an experimental group (n = 60) and a control group (n = 60). An additional exploratory sample of 60 students (8.37% of the total …

Potential Use Of Pump As Turbine Coupled To Self-Excited Induction Generator For Micro-Hydro Cooking And Cooling Applications, Emanuel J. Nyirenda

Tanzania Journal of Engineering and Technology (TJET)

Clean cooking and efficient cooling in developing countries have recently become areas of great focus. Further, the environmental impact of flooding in high-capacity hydroelectric plants has become a major concern. As a result, there is growing emphasis on developing sustainable and decentralized energy solutions, focusing on the potential of micro-hydro systems, especially in rural and remote areas. Although there are several alternative energy generation methods, their application is not straightforward. One of the latest technologies under research is using pumps as turbines coupled to an induction generator. This paper explores through a rigorous experimental approach the possibility of using a …

Gesture-Based Digital Currency Note Counting And Selection, Ajay Prasad

Defensive Publications Series

Current digital currency wallet interfaces often rely on repetitive single-note selection methods, such as individual swipes or taps, which can be inefficient and tedious for selecting multiple notes, particularly for larger transactions. This document describes a gesture-based interaction mechanism for digital currency applications. The mechanism allows a user to initiate a counting mode by tapping and holding a stack of virtual notes. While maintaining the tap, a user may slide their finger along the side of the stack, mimicking the action of counting physical bills, with haptic and visual feedback provided for each counted note. The disclosed technology may enhance …

From Paralysis To Heart Block: A Diagnostic Challenge In Andersen-Tawil Syndrome, Andrew Nguyen

Graduate Medical Education Research Journal

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When Milk Is Not Taken Out To Pasteur: A Case Study On Brucella In An Otherwise Healthy Child, Hunter Meyers

Graduate Medical Education Research Journal

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The Advanced Practice Provider’S Role In Fellow Medical Education And Training: A Mixed Methods Survey Study To Evaluate Current Educational Interactions, Perspectives, And Models, Jennifer Berger

Graduate Medical Education Research Journal

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Correlation Of Serial Lung Ultrasound Scores And Sonographic Measurements Of Diaphragmatic Excursion With Extubation Success In Intubated Nicu Patients Receiving A Dexamethasone Taper, Caleb Cave

Graduate Medical Education Research Journal

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Endovascular Management For Refractory Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (Tips) Creation, Jacob Schneider

Graduate Medical Education Research Journal

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Ventricular Tachycardia Ablation In Patients With Valvular Heart Disease, Fouad Khalil

Graduate Medical Education Research Journal

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Chronic Immunosuppression May Increase The Risk Of Coronary Artery Perforation In Patients Undergoing Cto-Pci, Mina Bhatnagar

Graduate Medical Education Research Journal

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Health Disparities Among Patients Referred To Multidisciplinary Heart Failure Clinic: A Retrospective Analysis, Garima Bhandari

Graduate Medical Education Research Journal

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