Digital Commons Network^™

Regulating Cutthroat Business, Luke Herrine

Articles

The production of meat is almost entirely controlled by a small group of multinational agribusinesses. These "packers" own everything from animal genetics to feed to wholesaling to slaughtering to butchering-leaving only the raising of the animals to nominally independent farmers, who are, in turn, controlled through one-sided contracts. Packers use this power both to push down costs and make raising and slaughtering animals more specialized and efficient and to extract more money from farmers, workers, retailers, consumers, and state and local governments. They also wield their resources to avoid accountability for the costs they impose on others and to shape …

The Role Of Cleavage And Polyadenylation Spcific Factor 6 (Cpsf6) In Hematopoiesis, Fengxi Ye

Dissertations and Theses (Open Access)

Cleavage and polyadenylation specific factor 6 (Cpsf6) translocation is frequently reported in APLL, which is Acute Promyelocytic Leukemia (APL)-like acute myeloid leukemia (AML) and other types of blood diseases associated with abnormal hematopoiesis. CPSF6 is a subunit of the Cleavage Factor I mammalian (CFIm) complex, which regulates post-transcriptional alternative polyadenylation (APA) of pre-mRNAs. Previous research indicated that Cpsf6 plays an essential role in alternative polyadenylation, development, and tumorigenesis. However, the role of Cpsf6 in hematopoiesis is unknown. Given its roles in APA, development and cancer, we hypothesize that Cpsf6 plays a critical role in hematopoiesis and that its …

Migratory Patterns Of Juvenile Shortfin Makos (Isurus Oxyrinchus): Evidence Of A Nursery In The Western North Atlantic, Julia A. Crews

Electronic Theses and Dissertations

Shortfin Makos, Isurus oxyrinchus Rafinesque, 1810, are lamnids that have a global distribution in temperate and tropical oceans. Locations of critical early life history events including birthing and nursery areas are unknown or unconfirmed for most populations. The objective of this study was to identify if a nursery area for Shortfin Makos in the northern waters of the Mid-Atlantic Bight using the criteria articulated by Heupel et al. (2007). Satellite tags were used to track the movement of juveniles (<200 cm TL, n=7) up to 5 months. Tag detections (n=882) confirmed that young makos stay in continental shelf waters of the northern Mid-Atlantic Bight off Long Island through the meteorological summer (June–August) and early meteorological fall (September–October) when sea surface temperatures are 18–23°C. There was clear migratory movement from juveniles once sea surface temperatures fell below 15°C. During late fall, some young sharks moved south towards Cape Hatteras, North Carolina, while one shark moved east up to 1,800 km into the open north Atlantic Ocean into meteorological winter. These movement data of juvenile Shortfin Makos combined with multi-year catches and sightings (2018–2024) provide strong evidence for a nursery area in the northern Mid-Atlantic Bight. By identifying a nursery area for Shortfin Makos, knowledge gaps that currently exist for this vulnerable species and support effective management can be closed.

Site Fidelity, Seasonality, Movement, And Fish Associates Of Sand Tigers Carcharias Taurus In North Carolina, Ara L. Mcclanahan

Electronic Theses and Dissertations

Sand tigers Carcharias taurus are mackerel sharks with a disjunct global distribution in tropical and temperate seas. In the northwest Atlantic, sand tigers migrate along the coast of the eastern United States from the Gulf of Maine to Florida and occupy structurally complex benthic habitats. The long-term, underwater camera installation, SharkCam, at Frying Pan Tower, off Cape Fear, North Carolina, USA, sits atop an expanse of hard bottom reef frequented by sand tigers. The citizen-science platform Spot A Shark USA (SAS USA) uses images of sand tigers to identify and track individuals. This study utilized image encounters from SAS USA …

A Multi-Isotope Investigation Of Mammoth Diet, Habitat, And Movement Patterns In The Central Great Plains, U.S.A., Jacob Mccloskey

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

During the Last Glacial Maximum (LGM), the Great Plains in Nebraska consisted of wooded parklands and grasslands, whereas spruce (Picea) forests, parklands, and steppe grasslands dominated east of the Missouri River. I analyzed bulk carbon (δ¹³C), oxygen (δ¹⁸O), and strontium (⁸⁷Sr/⁸⁶Sr) isotopes from tooth enamel in isolated mammoth (Mammuthus) molars to compare diet and movement patterns in two late Pleistocene assemblages: one in Nebraska (n = 24), and one in western Iowa and Missouri (n = 17). Furthermore, I identified a morphometric subset of molars as …

Evaluation Of Performance Characteristics And Groundwater Contamination Risks Associated With On-Farm Swine Carcass Disposal Via Composting And Shallow Burial With Carbon, Gustavo Castro Garcia

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation evaluates the performance of three on-farm swine carcass disposal methods: whole carcass composting (WCC), ground carcass composting (GCC), and shallow burial with carbon (SBC), focusing on biosecurity factors and groundwater contamination risks. Foreign animal diseases (FADs), such as African swine fever and classical swine fever, pose severe economic and animal well-being risks if introduced to the United States. With confirmation of an FAD, swine movement will be halted, creating an urgent need for practical, biosecure, and environmentally responsible on-farm disposal strategies for swine carcasses. Nebraska, as a leading swine-producing state, exemplifies the vulnerability of high-density livestock regions to …

Hormonal Modulation Of Sexual Approach And Avoidance Among Women With A History Of Sexual Trauma, Anneliis Susan Sartin-Tarm

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

A history of sexual trauma places women at a high risk for sexual dysfunction and other health sequelae, yet the influence of ovarian hormones in this population is poorly understood. This dissertation tested the theory that the effects of ovarian hormones are mediated by cognitive approach-avoidance systems to shape sexual well-being, and that this process is moderated by sexual trauma history. This was investigated across three studies examining the menstrual cycle, hormonal contraceptive use, and menopause. Across each chapter, I present complementary evidence demonstrating that hormones interact with the interpretation of ambiguous internal and external cues with respect to sexual …

Dreaming, Building, And Enduring Black Voices: Black Media In Omaha In The Post-Civil Rights Era, Elodie C. Galeazzi-Kelly

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation examines the purposes and roles of Black media in Omaha during the post–Civil Rights Era. It asks how African Americans and their allies in Omaha developed innovative media forms, institutions, and communication strategies to amplify Black voices, build community, and advocate for Black interests amid the rapidly shifting political and social landscape of the time. The study focuses first on three traditional forms of media (newspapers, radio, and television) and then broadens the definition of media to include key Black cultural institutions. These include a dramatic arts collective, a historical museum and archive, a memorial foundation, and an …

The Advancement Of Automation In Beef Packaging Pack-Off Systems, Matthew Newman

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Marble Technologies has developed a new system for beef, pork, and lamb producers that improves quality and worker experience in the packing of products. This work explores the augmentation of this system with the introduction of robotic packing to further reduce labor, increasing worker availability for value-added tasks.

Experimentation conducted to date has explored handling delicate meat products in the standard Marble system and the proposed robotic systems. These mechanical subsystems are critical intermediaries in safely and reliably delivering products to robots and from robots to boxes. Two case studies are presented to walk through the process and challenges of …

Egg White Hydrolysate In Hypertension: A Mechanistic Investigation Of Gut Microbiota Dependent And Independent Pathways, Emerson David Nolasco

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Cardiovascular diseases are one of the leading causes of mortality worldwide in which hypertension is a risk factor. Present pharmacological interventions require long-term adherence to the therapy and are often associated with undesirable side effects. Moreover, treatments have overlooked the role of the microbiome in the development of hypertension. Egg white hydrolysate (EWH) has exhibited antihypertensive properties with potential to be used as a natural alternative for the prevention and management of hypertension. However, EWH peptide’s effect on the gut microbiome remains yet to be elucidated. Studies have described that a portion of the ingested protein can remain undigested as …

Functional Genomics Of Phosphatidylcholine Biosynthesis In Saccharomyces Cerevisiae, Amanda Marie Maliva

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Phosphatidylcholine (PtdCho) is a prominent structural building block of cell and organelle membranes in animal, plant, and fungal cells and some bacteria. Due to its abundant nature in the plasma membrane and intracellular organelle membranes in eukaryotes, the biosynthesis of PtdCho must remain regulated to preserve the correct membrane lipid composition. Dysregulations in PtdCho metabolism can lead to mitochondrial dysfunction, cell death, and the development of diseases including cancer, atherosclerosis, and hepatic diseases. Knowledge of PtdCho has remained limited to the genes involved in its three biosynthetic pathways (Kennedy (K), methylation (M), and acyltransferase (A)), despite the growing realization of …

Characterization Of Undergraduate Biology Instructors’ Goals And Strategies For Implementing Quantitative Reasoning, Anum Khushal

School of Natural Resources: Dissertations, Theses, and Student Research

Quantitative reasoning (QR) is the application of mathematics and statistics to real-life and scientific contexts. It is essential for understanding complex biological phenomena and analyzing large datasets in both academic and professional settings. In response to the growing demand for QR skills, biology educators and researchers have engaged in curricular reforms and education research. This qualitative study explores how undergraduate biology instructors integrate QR into their teaching using a framework informed by pedagogical content knowledge (PCK) and QR. The study involved 21 biology faculty from various U.S. institutions who intentionally incorporated QR in their instruction. Data was collected through semi-structured …

Aptamer Selection And Development Of Electrochemical Aptamer-Based Sensors For Neuropeptide Y, Evelyn Adela Carreto Guevara

Department of Chemistry: Dissertations, Theses, and Student Research

In this thesis, we report the results of four aptamers obtained from an aptamer selection process called the systematic evolution of ligands by exponential enrichment (SELEX) with affinity to Neuropeptide Y (NPY). NPY is a highly abundant peptide transmitter with widespread distribution throughout the body which affects various physiological functions. These functions include energy homeostasis, appetite regulation, stress response, and anxiety regulation. Dynamic monitoring of NPY levels is crucial for better understanding behaviors in individuals with neurological disorders associated with NPY. Aptamers are synthetic oligonucleotides obtained through SELEX which have a binding affinity to a target of interest when in …

Depuration Of A Solitary Ascidian Depletes Transient Bacteria Without Altering Microbiome Alpha-Diversity, Brenna Hutchings, Susanna López-Legentil, Lauren M. Stefaniak, Marie L. Nydam, Patrick M. Erwin

Marine Science

Depuration, or the process of clearing impurities from the gut, is commonly applied to marine food products due to its efficacy in removing human pathogens from shellfish and edible ascidians. Recent studies also reported that depuration of filter-feeding animals helped reduce transient bacteria and identify resident symbionts in gut microbiome studies. Here, we examined the impact of depuration on bacteria in the branchial sac, gut, and hepatic gland of the solitary ascidian Pyura vittata. Replicates were kept in filtered seawater for 4 days prior to dissection (aquaria-depuration) and compared to samples that were immediately processed following collection (wild-no depuration) and …

Scaling Laws Of Political Regime Dynamics: Stability Of Democracies And Autocracies In The Twentieth Century, Paula Pirker-Diaz, Matthew Wilson, Soenke Beier, Karoline Wiesner

Faculty Publications

In light of the current rise of authoritarian regimes and the anti-liberal tendencies in some established democracies, understanding the dynamic and statistical properties of political regimes is of critical importance. Despite their relevance, a comprehensive quantitative assessment of these dynamics on a historical scale remains largely unexplored, and the notion that democratization is an irreversible process has gone mostly unchallenged. This study provides a rigorous and quantitative analysis of political regimes worldwide by examining changes in freedoms of expression, association and electoral quality throughout the twentieth century. Utilizing the multidimensional V-Dem dataset, which covers over 170 countries across more than …

Visceral, Neural, And Immunotoxicity Of Per- And Polyfluoroalkyl Substances: A Mini Review, Pietro Martano, Samira Mahdi, Tong Zhou, Yasmin Barazandegan, Rebecca Iha, Hannah Do, Joel Burken, Paul Ki-Souk Nam, Qingbo Yang, Ruipu Mu

Chemistry Faculty Research & Creative Works

Per- and polyfluoroalkyl substances (PFASs) have gained significant attention due to their widespread distribution in the environment and potential adverse health effects. While ingestion, especially through contaminated drinking water, is considered the primary route of human exposure, recent research suggests that other pathways, such as inhalation and dermal absorption, also play a significant role. This review provides a concise overview of the toxicological impacts of both legacy and emerging PFASs, such as GenX and perfluoro butane sulfonic acid (PFBS), with a particular focus on their effects on the liver, kidneys, and immune and nervous systems, based on findings from recent …

Bridging Theory To Practice: An Evidence-Based Training Program For Implementing Animal-Assisted Therapy In Appalachian Clinical Settings, Lauren Kessler

Occupational Therapy Doctorate Capstone Posters

No abstract provided.

The Use Of Sensory Interventions For Stress Management In College Students, Cassidy Cain

Occupational Therapy Doctorate Capstone Posters

For my doctoral capstone, I partnered with the Student Success Center (SSC) at Eastern Kentucky University and the director of the SSC, Dr. Ashley Sweat, to explore the connections between commonly used occupational therapy sensory intervention techniques and stress management for college students. The focus of my project is education and program development for the Student Success Center. In my literature review, I identified stress as one of the largest contributors to students not returning to college. The Student Success Center provides services for students who are already at a high risk of not continuing their college education. Based on …

3,5-Dihydroxy-4-Isopropylstilbene (Tapinarof) Is A Partial Aryl Hydrocarbon Receptor Agonist In Fish, Conner A. Dicks

All Theses

The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is essential in regulating development, immune homeostasis, and drug and xenobiotic metabolism. Activation of the AHR by specific ligands results in its translocation to the nucleus where it induces a myriad of gene products, including cytochrome P450 (CYP) drug metabolizing enzymes (e.g., CYP1A1) and other components of the chemical defensome, as well as inflammatory control. Interestingly, the AHR can bind a wide variety of endogenous and xenobiotic ligands which are able to induce unique downstream effects dependent on cell type, inflammatory context, and ligand stability. The AHR is …

Azalea Regional Welcomes New Library Manager, Ivy Corder

Georgia Library Quarterly

No abstract provided.

Low Energy Ion Irradiation Effects In Electronic Devices And Materials, David C. Mccall

All Dissertations

The physics and engineering of ion-solid interactions are governed by the ion beam characteristics (flux, charge, energy) and target(s) in question. Here I present work on two projects related to the extraction of a high flux of low charge state Argon ions from a commercial plasma source and the irradiation of an engineered target, a transistor, with high charge state Argon ions.

An end-Hall ion source that produces a a high current plasma of ions and electrons in a rough vacuum environment is characterized. Using a Langmuir probe and multiple pressure measurements, the ion and electron content of the source …

Partition, Passport And The Documentary Life Of Belonging, Haimanti Roy

History Faculty Publications

As India and Pakistan emerged as two new nation-states after 1947, questions around nationality and citizenship animated official and public discourses. While there were constitutional and legal pronouncements to clarify these matters, this article suggests that particular documents governing mobility became central to how such issues were framed and understood. In particular, this article focuses on the Indian passport and similar documents of mobility control, such as the domicile certificate, permits, and so on, to examine how they worked singly and in conjunction to frame the documentary life of belonging. The article also focuses on particular mobile groups, Muslim minorities …

Cognitive And Affective Factors Related To Geoscience Academic And Career Choice, Amanda Diane Manzanares

Dissertations

Recruitment and retention continue to be a challenge for Science, Technology, Engineering, and Math (STEM) fields. Research shows that both cognitive and affective factors influence student learning, which can then shape academic and career choice. Therefore, my alternatively formatted dissertation includes three articles examining two STEM disciplines: geosciences and Interdisciplinary Environmental and Sustainability programs adding to prior research and further uncovering specific factors that could predict student educational and professional aspirations.

Regarding cognition, students often begin STEM courses with pre-existing mental frameworks, also referred to as schemas that are formed by their prior experiences. These schemas may conflict with established …

Updates To Administrative Coding Systems Limits Longitudinal Study Of Patients With Congenital Heart Disease., Natalie Jayaram, Dhaval Chauhan, Matt Hall, Janelle R. Noel-Macdonnell Phd, Philip M. Allen, Brett R. Anderson

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Truth, Justice, And The American Way: Negotiating Identity Among Superhero Cosplayers At International Comic Book Conventions, James Scanlan

Graduate Theses and Dissertations

Cosplay performances in convention spaces, and the increasing commercialization and commodification of both, remain largely unexplored domains that are rapidly expanding into global phenomena. The influx of capital internationally and the growing popularity of cosplay and conventions offers the opportunity to document and describe processes of performance, identity construction, and negotiation of the global phenomena within local contexts (“glocalization”) in non-Western spaces. I conducted ethnographic research at more than half a dozen research sites throughout Europe, the Middle East, South Asia, East Asia, and South and Central America, photographing convention spaces and cosplayers and conducting interviews with cosplayers. By focusing …

Onward, Christian Soldiers: The Material Rhetoric Of Becoming Fascist In Parachurch Scouting Organizations, Madeline Aubrey Studebaker

Graduate Theses and Dissertations

This thesis provides a material rhetorical analysis of Trail Life USA and American Heritage Girls, two Christian nationalist scouting organizations that aim to renew and restore their cultural dominance across America. In examining how these programs route children’s bodies through ritual and affective indoctrination, I find that a fascist becoming underpins these groups’ (re)production of perfect, patriotic children. The first chapter discusses how boys enrolled in Trail Life USA become fascist as self-defense against American boyhood’s perceived eradication. Trail Life USA restores masculinity through rituals of autogenetic sovereignty, returns to originality through homosocial and affective intensity, and invocations of exceptional …

Environmental Drivers Of Vegetation Dynamics In Constructed And Natural Wetlands Of The Chihuahuan Desert, Enrique David Garcia

Open Access Theses & Dissertations

Desert wetlands are critical ecosystems that provide water, food, and habitat for many different species at different trophic levels. Additionally, they have the capacity to recharge aquifers, control floods, and purify water, among others. Unfortunately, they have been facing multiple environmental challenges due to different human activities, sometimes with disastrous consequences. There is an urgent need to better understand the structure and function of wetlands of different types and in different biomes in order to conserve, restore, and even create them so we can continue to obtain all the ecological services they provide. In this dissertation, I investigated how environmental …

Cellular And Noncellular Influences On Lipid Nanoparticle Tropism In The Liver, Mario Yomir Mata Corral

Open Access Theses & Dissertations

Hepatocellular carcinoma (HCC) is currently ranked as the second leading cause of cancer-related mortality worldwide, causing more than 700,000 deaths a year. The liver is important in blood filtration and metabolism, and for this reason is a prime target for drug delivery, with lipid nanoparticles (LNPs) showing promise as carriers due to their natural hepatic tropism. However, LNP efficacy is decreased in HCC due to the limited understanding of liver physiology in cancerous environments. This project proposes to address this gap by using a tissue-clearing technique known as CLARITY along with a chemically tagged LNP for comprehensive visualization of LNPs …

Spatial And Thermal Aspects Of The Ecology Of Three Sympatric Rattlesnakes In The Montane Northern Chihuahuan Desert, Joshua James Mead

Open Access Theses & Dissertations

To understand how animals coexist on the landscape, the individual aspects of a species life history must first be understood. Animals need to find locations that provide the resources they need to survive. Movement, microhabitats, and temperature can alter such areas where animals occur. Understanding animal movements provide important information on space use and microhabitats on the landscape. Ectothermic animals must acquiesce to ambient temperatures or use behavioral modifications to alter their body temperature. The ability to maintain suitable body temperature is essential for physiological function, reproduction, and ability to avoid predation. Research on the variation in a species ecology …

Expression Of Glycine Transporter 1 In The Rodent Basal Ganglia: Glial Vs. Neuronal, Rosa Atziri Perez

Open Access Theses & Dissertations

Glycine functions as an inhibitory neurotransmitter in the central nervous system (CNS),and it is mainly involved in autonomic functions. The levels of extracellular glycine are regulated by two membrane transporters, glycine transporter 1 and glycine transporter 2 (GlyT1 and GlyT2, respectively). These transporters differ in function and localization within the CNS. For many years, studies suggested that only GlyT2 served as a neuronal marker; however, GlyT1 has been localized in neurons in recent studies. The expression of GlyT1 is widespread compared to GlyT2; hence, the main objective is to determine the nature of the expression of GlyT1 in areas devoid …