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Investigating Factors That Affect Total Ige Antibody Levels Of A Canine Population In Louisville, Ky, Iris N. Gillespie

Undergraduate Theses

Canine atopic dermatitis (CAD) is a genetically predisposed condition that causes inflammatory and pruritic (itchy) skin reactions in response to environmental and food allergens. The main purpose of this study is to determine if there is a correlation between pollen counts and total canine IgE antibody levels of dogs living in Louisville, KY. Additionally, data is analyzed to look for trends documented in previous studies related to the impacts of sex, age, and allergic symptoms on total IgE count. In collaboration with the Downtown Animal Hospital, blood samples were drawn from 16 dogs at one point in February (when pollen …

Insm1 Governs A Neuronal Progenitor State That Drives Glioblastoma In A Human Stem Cell Model, Patrick A Desouza, Matthew Ishahak, Xuan Qu, Colin Mccornack, Devi Annamalai, Diane D Mao, Rajanikanth Vangipurapu, Yiwei Fu, Alexandre T Vessoni, Ryan T Cleary, Rowland H Han, Punn Augsornworawat, Timothy Woodiwiss, Darby Agovino, Braxton Sizemore, Jessica Kline, Maryam Borhani-Haghighi, Hao Chen, Sangami Pugazenthi, Hiroko Yano, Ting Wang, Luis F Z Batista, Jeffrey R Millman, Albert H Kim

2020-Current year OA Pubs

Glioblastoma is a lethal brain cancer marked by functional plasticity driven by tumor cell-intrinsic mutations and their interplay with developmental programs. To investigate how canonical glioblastoma mutations promote functional plasticity, we have developed an isogenic human neural stem cell (NSC) model of glioblastoma by sequential addition of TERT promoter, TP53, and PDGFRA point mutations. TP53 loss-of-function increases TERT expression during serial mutagenesis, but only triple mutant NSCs reliably form lethal brain tumors in vivo that recapitulate glioblastoma. Tumor cell evolution triggers stress-related metabolic changes and transitions toward a neuronal progenitor network driven by transcription factor INSM1. INSM1 is highly expressed …

The Importance Of A Pressure Injury Prevention Program In Acute Hospital Settings, Sarah Orial

Student Scholarly Projects

Practice Problem: The identified practice problem for this project was the lack of a standardized pressure injury prevention program in a 350-bed acute care hospital. The lack of a standard program could be leading to increased hospital-acquired pressure injuries. PICOT: In adult inpatients in a medical/surgical unit (P), does the implementation of a standard unit-based pressure injury prevention program (I) compared to the current practice (C) increase the percentage of nursing skin risk assessment documentation (O) over a 10-week period (T)?

Evidence: The literature supports the development of standard pressure injury prevention programs and continuing education to …

Anticonvulsant Activity Of Simvastatin On Experimentally Induced Epileptic Seizures In Mice, Uday Abdul-Reda Hussein, Nargis Amer Nayef, Baneen Adel Abdul-Hussein, Tamara Hassan Mawazi, Zahraa Kadhim Hussein, Noor Alhuda Ali Saadon, Zainab Mohammed Abd, Fatima Mohammed Alwan, Huda Bassim Latif, Hassanein Mohammed , Razak, Mohammed Rida Majeed, Mohammed Abdul-Elah Abdul-Hamid

Al-Ameed Journal for Medical Research and Health Sciences

Background: Epilepsy is a common neurological disorder characterized by recurrent seizures. Simvastatin was recognized as a new candidate that exhibits a variety of neuroprotective effects, including antioxidant and anti-inflammatory effects that have the ability to inhibit neuronal hyperexcitability and seizure susceptibility.

Aim: The purpose of this study is to assess the possible anticonvulsant action of simvastatin in the mouse seizure model.

Material and Methods: The eighteen adult albino mice (25–30 g) were allotted randomly to three groups (n = 6). Thirty minutes before the induction of convulsion, the groups received different intraperitoneal pretreatments: Group 1: Distilled water (0.1 ml), Group …

Proteome-Wide Association Study Of Prostate Cancer Risk Across Populations, Hua Zhong, Jingjing Zhu, Shuai Liu, Chong Wu, Liang Wang, Seamus P. Whelton, Catherine H. Marshall, Michael J. Blaha, Peter Durda, Xiuqing Guo, Craig W. Johnson, Henry J. Lin, Kent D. Taylor, Russell P. Tracy, Ronit I. Yarden, Ani W. Manichaikul, Stephen S. Rich, Jerome I. Rotter, Rajat Deo, Ruth F. Dubin, Peter Ganz, Lang Wu

School of Graduate Studies Faculty Publications

There is insufficient understanding of the molecular basis of prostate cancer (PCa) across different populations. We perform a large-scale proteome-wide association study (PWAS) to identify proteins with genetically regulated expression in plasma to be associated with PCa risk across populations. We develop genetic prediction models for expression of 1578, 1993, 1218, and 1390 proteins for African (n = 450), European (n = 758), Asian (n = 289), and Hispanic/Latino (n = 474) males, respectively, and evaluate associations of genetically regulated protein expression with PCa risk in 19,391 PCa cases and 61,608 controls of African population, 122,188 cases and 604,640 controls …

Double Burden Stress In Women And The Role Of Psycho-Religious Worship In Alleviating It, Fahmi Mandala Putra, Zata Ismah, Rizky Indah Syahfitri, Citra Cahyati Nasution, Az-Zahra Atika Putri, Fitria Amirah, Tri Amelia Rahmitha Helmi

Folia Medica Indonesiana

It has been recognized that women are twice as likely to experience depression compared to men. In addition to biological vulnerability, there is also a combined effect of bearing the burden of household responsibilities while contributing financially through employment. One coping strategy that helps women endure these challenges is meditation, which in Islam includes the practice of dhikr (remembrance of God). This study aims to analyze the phenomenon of double burden stress in women and how psychoreligious practices can help reduce stress levels. The study employed a prospective cohort design, tracking the respondents' dhikr habits over a 21-day period. On …

Elm: The Case Of Experiential Programming, Matthew Miller, Lynette Campogiani

Faculty and Staff Publications & Presentations

Experiential Programs (EPs) provide immersive, destination-focused experiences within luxury resort settings. However, research has yet to apply the elaboration likelihood model (ELM) to examine how guests evaluate their experiences with EPs, particularly within luxury tourism or resort contexts. Using the ELM framework, this study examined how the experience of luxury resort EPs influences guests’ revisit intentions. Guests’ experiences were categorized into central and peripheral processing cues and qualitative interview responses were analyzed. The findings indicate that elements such as ambient music and scenic views associated with peripheral processing had a significantly stronger positive impact on guests’ intentions to return than …

Actin Dysregulation Induces Neuroendocrine Plasticity And Immune Evasion: A Vulnerability Of Small Cell Lung Cancer, Yoojeong Seo, Shengzhe Zhang, Jinho Jang, Kyung-Pil Ko, Kee-Beom Kim, Yuanjian Huang, Dong-Wook Kim, Bongjun Kim, Gengyi Zou, Jie Zhang, Sohee Jun, Wonhong Chu, Nicole A Kirk, Ye Eun Hwang, Young Ho Ban, Shilpa S Dhar, Joseph M Chan, Min Gyu Lee, Charles M Rudin, Kwon-Sik Park, Jae-Il Park

Faculty, Staff and Student Publications

Small cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. Capping protein inhibiting regulator of actin dynamics (CRACD) that promotes actin polymerization, is frequently inactivated in SCLC. However, the role of CRACD loss in SCLC is unknown. Here we show that CRACD depletion drives neuroendocrine (NE) cell plasticity and immune evasion in SCLC. Mechanistically, CRACD inactivation disrupts actin organization, leading to suppression of Yap1-NOTCH signaling and subsequent NE gene upregulation. Simultaneously, CRACD loss drives EZH2-mediated histone methylation via nuclear actin disruption, leading to repression of MHC-I genes and depletion of CD8⁺ T cells. Consequently, CRACD-downregulated tumors exhibit …

An Updated Annotated Checklist Of The Mammals Of The Crane Trust, Hall County, Nebraska, Bethany L. Ostrom, Amanda H. Medaries, Andrew J. Caven, Jenna M. Malzahn, Alexa Rojas, Matthew R. Schaaf, David M. Baasch, Thomas E. Labedz, Greg D. Wright

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The Crane Trust is a regional nonprofit conservation organization that has protected land in the biologically important Central Platte River Valley for over four decades. A mammal inventory was conducted on the Crane Trust’s main habitat complex in 1980. Since, a variety of environmental conditions have shifted locally, regionally, and globally. An analysis of the mammal community was conducted using past and recent data to determine how species composition and relative abundance have shifted categorically from 1980 to 2021. We used all available data to categorize relative abundance during two distinct time periods per a modified “DAFOR” scale including 7 …

Evaluation Of Antibacterial Activity Of Amaranthus Spinosus Extract Against Streptococcus Mutans: An In-Vitro Study, Fakhrun Nisa, Juen Carla Warella, Valentine Hursepuny, Johan Bruyif Bension, Khairunnida Rahma

Folia Medica Indonesiana

Streptococcus mutans is a component of the normal oral flora that can become a primary pathogen, leading to dental caries and tooth decay. Tooth decay and dental caries are the most common oral health issues worldwide. Treatment of dental caries and tooth decay represents a crucial effort in addressing global health concerns. One alternative treatment the community used to treat dental caries and tooth decay is thorn spinach (Amaranthus spinosus). Thorn spinach leaves contain bioactive compounds with potential antibacterial properties, including flavonoids, tannins, saponins, and alkaloids. This study aimed to evaluate the antibacterial activity of thorn spinach leaf …

Sex Hormones Influence Ormdl3 Expression: Implications For Sex-Associated Asthma Phenotype, Elisabetta Granato, Ida Cerqua, Antonietta Rossi, Maria Antonietta Riemma, Maria Chiara Monti, Giusy Ferraro, Barbara Romano, Maria Francesca Nanì, Danilo D'Avino, Martina Simonelli, Joshua Malo, Francesca Polverino, Bruno D'Agostino, Giuseppe Cirino, Fiorentina Roviezzo

Faculty, Staff and Students Publications

Background: Genetic polymorphisms in sphingolipid metabolism, particularly involving the orosomucoid-like 3 (ORMDL3) gene, have been associated with asthma risk. Notably, asthma prevalence and severity exhibit pronounced sex differences, emerging in childhood and persisting into adulthood. However, the molecular mechanisms underlying this sexual dimorphism remain incompletely elucidated.

Objective: We investigated whether ORMDL3 contributes to sex differences in airway function and asthma-like features.

Methods: ORMDL3 expression was measured in lung tissues from healthy male and female human donors and in human bronchial epithelial cells (BEAS-2B) after exposure to 17β-estradiol (E2), Dermatophagoides pteronyssinus 1 (Der p 1), or both. A murine preparation of …

Islamic Prophetic Counseling: An Intervention Strategy In Developing Students' Noble Character, Hardi Santosa, Ahmad Zaki Annafiri, Iin Inawati, Akhmad Fajar Prasetya, Muhammad Sabri Bin Sahrir

Buletin Konseling Inovatif

This study aims to test the effectiveness of Islamic prophetic counseling in developing students' noble morals. The research method uses a true experiment involving a control group. The selection of the control group uses the waiting-list control group model, with consideration of the ethical aspects of the study. The research sample involved 244 students captured the profile of noble morals and their spiritual activism. While the hypothesis test involved 50 students who were divided into control and experimental groups. The sample selection was carried out randomly with the random assignment technique. The research data were collected using a noble moral …

Private Foundations And Tax Reform: Composition And Concepts, William J. Lehrfeld

Tax Adviser

No abstract provided.

A Distance Based Embedding Method Using Nlp Methods To Identify Proximity To A Network, Shuhan Zhang, Anurag Tangri, Chinmay Narendra Sonar, Lin Meng, Can Liu, Chiranjeet Chetia

Defensive Publications Series

The present disclosure relates to the field of Artificial Intelligence (AI), in particular to AI methods and systems for analyzing transactional data using Natural Language Processing (NLP) techniques to identify latent relationships and proximity within networks. The disclosed system utilizes text fields within datasets to categorize input data into appropriate classifications. The input comprises a dataset containing text data that provides contextual information related to transactions. Feature embeddings are generated using a sentence-based Language Learning Model (LLM), which captures semantic meaning of sentences. The LLM converts input data of varying lengths into fixed-dimension embeddings. The sentence-based LLM is fine-tuned based …

Artificial Minds, Alien Experiences: Navigating The Uncharted Territory Of Ai Phenomenology, Kevin H. Smith

University of Memphis Law Review

This Article advocates for a fundamental shift in the way artificial intelligence (“AI”) consciousness is evaluated, moving beyond anthropocentric models that rely on human cognitive benchmarks. Traditional tests, such as the Turing Test, assume that human-like behavior is the ultimate criterion for consciousness, overlooking the possibility of novel, non-human modes of consciousness. Instead, this Article proposes a multi-dimensional framework that assesses AI systems based on their unique architectures and cognitive processes. By combining dimensions such as information integration, autonomous goal-pursuit, metacognitive self-modeling, affective motivation, social communication, counterfactual simulation, imaginative reasoning, and causal modeling, this framework provides a comprehensive and empirically …

The Restatement Of Torts And Recovery For Loss Of The Human-Pet Bond Aftern An Intentional Tort, Merle H. Weiner

University of Memphis Law Review

Owners1 of pets2 are often unable to recover for the loss of the human-pet bond when their pets are tortiously injured or killed. However, empirical research confirms the owners may experience the loss as real harm.3 Pets have an especially important role in a “stressful and frenetic” world characterized by unstable family relationships.4 Indeed, a 2015 Harris Poll found that 95% of American dog and cat owners regard their pets as family members.5 This Article seeks to explain why some courts refuse to allow recovery for loss of the human-pet bond even in cases involving intentional torts, such as conversion …

The Tax Adviser, Volume 1, Number 3, March 1970, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Insights Into The Economic Aspects Of Egyptian Fisheries And Their Impact On Fishermen Communities, Noura Hassan

Blue Economy

This review highlights the economic aspects of Egyptian fisheries and their impact on fishing communities. Local fish production increased by about 46% between 2012 and 2021, yet consumption demand continues to outpace supply, creating a food gap that is filled through imports. Fish imports peaked in 2019 at around 506 thousand tons, putting pressure on Egypt’s trade balance. Fish is a key dietary component for Egyptians, offering a relatively affordable source of protein compared to red meat and poultry. However, production from natural fisheries (seas, lakes, and the Nile) faces numerous challenges such as overfishing, pollution, weak management, and environmental …

The Student Movement Volume 110 Issue 10: Joy To The World Changers, Anna Rybachek, Aiko J. Ayala Rios, Corinna Bevier, Caleb Chung, Megan Constantine, Jj Nixon, Andrew Francis, Isa Demoraes, Ayanda Dewa, Timi Olatunde, Joey Carrion, Moraya Truman, Madison Vath, Nathaniel Reid, Nicoleta Cojan

The Student Movement V. 110 (2025-2026)

ARTS & ENTERTAINMENT

The Origins of Classic Christmas Traditions, Anna Rybachek

Feel the Joyful Christmas Spirit with the Music Department, Aiko J. Ayala Rios

Labubus and The Rockettes: A Macy's Parade for Everyone, Corinna Bevier

The Christmas Tradition, Caleb Chung

HUMANS

The Power of Pairing: Andrews Students Build Bonds Through Best Buddies, Megan Constantine

Charting Her Path: Aleah Crayton's Andrews Experience, JJ Nixon

NEWS

Former Student Missionaries Start New "Project Launch" Initiative with CFE, Andrew Francis

Andrews Students Spread Kindness on Second Show Love Here Day, Isa DeMoraes

IDEAS

One Swipe Away from Destiny, Ayanda Dewa

When an "I Love …

The Making Of Constantinople Ii: Reception And Renewal Of Conciliar Christology, A.D. 428–553, Joshua Miller

Dissertations (1934 -)

The Second Council of Constantinople in 553, recognized by many Christian traditions as the fifth ecumenical council, represents a pivotal moment in the development and articulation of the Church’s understanding of the central mystery of her faith, that of the Incarnation of the Word of God who is Jesus Christ. Constantinople II provides a clarification of the symmetrical statement of Christology produced at the Council of Chalcedon in 451 by reading it in continuity with the preceding conciliar tradition, especially the Council of Ephesus in 431, and by retrieving neglected tenets of Cyril of Alexandria’s more asymmetrical account of Christology, …

From Collision To Coexistence: Data-Driven Approaches To Reducing Wildlife Rehabilitation Center Intakes, Alice Anastos

Honors Projects

This project investigates the primary anthropogenic drivers of wildlife admissions at Lake Erie Nature and Science Center using a quantitative analysis of 10,172 intake records from the WILD-ONe database. Window collisions were by far the leading cause of admission, accounting for 54% of all intakes. Orphaning represented 12%, followed by vehicle collisions (5%) and domestic cat attacks (4%). By integrating findings from current wildlife rehabilitation research, this study identifies evidence-based strategies, such as bird-safe window treatments, public education on natural animal behavior, and targeted urban planning, that can substantially reduce preventable injuries. These results underscore the need for context-specific outreach …

Holistic Approaches To Lyme Disease Symptom Management, Leah Van Antwerp

Honors Theses

Lyme disease is a multisystem tick-borne infection that can lead to long-lasting symptoms even after standard antibiotic therapy, with Lyme arthritis being one of the most common and persistent complications. Due to limited research on this issue, rheumatoid arthritis (RA) will be discussed as a reference for understanding treatment options because it is a similar condition. Since many people continue to experience debilitating pain and reduced quality of life after treatment for Lyme disease, holistic approaches have become increasingly popular for symptom management. This literature review examines three holistic modalities-yoga, acupuncture, and diet modifications- and their effectiveness in alleviating arthritic …

Plant Vs. Animal Protein: Effect On Recovery, Performance, And Long-Term Health, Claudia Stachura

Honors Theses

Protein plays a fundamental role in muscle repair, growth, and athletic performance, which has led to increased interest in how different protein sources compare, particularly as plant-based diets become more common among athletes and physically active individuals. The debate surrounding plant-based versus animal-based protein sources primarily focuses on differences in protein quality, amino acid composition, digestibility, and potential long-term health implications. This paper examines current evidence comparing the effectiveness of plant and animal protein sources in supporting muscle protein synthesis (MPS), resistance training adaptations, recovery, and performance, while also considering broader health and environmental outcomes.

Protein supports muscle growth by …

Semantic Networks In Relapsing-Remitting Multiple Sclerosis Exhibit Reduced Efficiency, Interconnectivity, And Flexibility, Sophia Lall, Jennifer Pardo, Joshua Sandry

Department of Psychology Faculty Scholarship and Creative Works

Background

Word-finding deficits are common in persons with relapsing-remitting multiple sclerosis (pwRRMS); this may be related to the inefficient organization of semantic information.

Objective

To understand whether the semantic organization and semantic retrieval are impacted in pwRRMS.

Methods

Semantic fluency data from 64 pwRRMS and 73 controls was utilized to (1) derive standard verbal fluency measures using the Semantic Network and Fluency Utility R package and (2) build semantic networks via the correlation-based network approach in the SemNet R package. Subjective word-finding concerns were assessed in a subgroup of the sample. Group differences were evaluated.

Results

PwRRMS endorsed more frequent …

The Good Life And Human Flourishing: Timeless Principles From Aristotle To Tolstoy, Daniel Mark Kelly

Honors Capstone Projects and Theses

No abstract provided.

Influence Of Lunar Light On Vertical Distributions Of Myctophid, Hygophum Taaningi, Meta Hughes

All HCAS Student Capstones, Theses, and Dissertations

Hygophum taaningi (Myctophidae) likely undertakes lunar vertical migration (LVM), an asynchronous migration, but there is a lack of literature supporting this behavior in the northern Gulf of Mexico basin. The aim of this study was to assess how effective modeled lunar phase and lunar light intensity are at predicting standardized counts of H. taaningi in the northern Gulf. The R package moonlit was used to provide retroactive calculations of lunar phase and lunar light intensity for standardized count data from the Offshore Nekton Sampling and Analysis Program (ONSAP). A generalized additive model (GAM) was used to investigate the relationship between …

“Chords Of Inquiry”: Alternate Guitar Tunings, Harmony, And Text-Music Relations In Joni Mitchell’S Early Songs, Peter Kaminsky, Megan Lyons

Open Access Fund Publications

In the 2003 documentary Woman of Heart and Mind, Joni Mitchell states, “Chords are depictions of emotions. These chords that I was getting by twisting the knobs on the guitar until I could get these chords that I heard inside that suited me, they feel like my feelings. You know, I called them, not knowing, chords of inquiry.” In investigating Mitchell’s music, we address the integration of guitar, harmony, and expression of feeling exemplified by “chords of inquiry.” We take as a corpus her early songs from 1968 to 1972 in which she accompanies herself on guitar. Our study …

U-Glide Program Fall 2025, Unf Office Of Undergraduate Research, Unf Graduate School

Undergraduate – Graduate Learning, Inquiry, and Distinctive Experimentation (U-GLIDE) Symposium Programs

No abstract provided.

Radiation-Induced Brachial Plexopathy: Current Understanding, Diagnosis, And Treatment Options, Alex G. Lambi, Tomas Holly, Ryan E. Tomlinson, Mary F. Barbe

Department of Orthopaedic Surgery Faculty Papers

Radiation-induced brachial plexopathy (RIBP) is a gruesome complication of cancers treated with radiation therapy around the lung and chest wall, head and neck, and breast and axilla. It can occur in an early-onset (transient) or a late-onset (chronic) fashion. The diagnosis involves exclusion of a compressive neoplastic process, either new or recurrent, and relies largely on patient symptomatology without well-validated, objective scoring systems. Treatment options remain limited as no major advances have been made to prevent or halt disease progression. This article reviews the background incidence, pathophysiology, and diagnosis of RIBP. In addition to surgical treatment options, nonsurgical modalities, often …

Sharks On The Move: Investigating The Link Between Climate Change And Rising Shark-Human Encounters, Keira E.B. Blakey

USF St. Petersburg campus Honors Program Theses (Undergraduate)

Sharks have long captivated the public imagination, evoking fascination and fear through enduring myths and media portrayals of negative interactions with humans. In recent years, an increase in shark sightings and attacks along the U.S. coastline has prompted scientific inquiry and public concern. This literature review explores the relationship between rising global temperatures and the frequency of shark attacks, focusing on how climate change affects shark behavior, migration patterns, and habitat distribution. Sharks move into warmer waters as ocean temperatures rise, altering migration routes and prolonging active seasons. This increases the likelihood of shark-human encounters, particularly in coastal regions that …