Digital Commons Network^™

Development Of A Procedure For Prion Surveillance In The Laboratory Setting, Damian Gorski, Isaac Schauer, Kane Spicker, Ananya Tupaki-Sreepurna, Fei Wang, Claudio Soto, Sandra Pritzkow

Faculty, Staff and Student Publications

Infectious prions readily adhere to common surfaces, retain infectivity, and are highly resistant to conventional decontamination, posing significant biosafety challenges in the medical and research environments. Recent occupational exposures underscore the urgency of improving safety measures. Here, we describe an approach combining foam-swab surface sampling and protein misfolding cyclic amplification to enhance prion surveillance. Our results demonstrate the ability to detect prions most relevant to human health directly from contaminated surfaces, even at 100 million-fold dilutions of the brain. We applied our method to assess the completeness of prion decontamination and show that high prion quantities can resist even approved …

Updating The Epidemiology Of Blastomycosis And Histoplasmosis In The United States, Using National Electronic Health Record Data, 2013-2023., Juliana G E Bartels, Simon K. Camponuri, Theo T. Snow, Brittany L Morgan Bustamante, Natalie J. Kane, Rose Reynolds, Aidan Lee, Mark A. Hoffman, Theodore C. White, Justin V. Remais, Jennifer R. Head

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Where surveillance data are limited, nationally representative electronic health records allow for geographic, temporal, and demographic characterization of the fungal diseases blastomycosis and histoplasmosis.

METHODS: We identified incident blastomycosis and histoplasmosis cases from 2013 to 2023 within Oracle EHR Real-World Data, which comprises 1.6 billion healthcare encounters nationally. To characterize spatiotemporal incidence trends, we used generalized estimating equations weighted for nonrepresentativeness of electronic health record-reporting facilities. We computed standardized incidence rate ratios (sIRRs), which relay relative differences in standardized incidence rates between regions, race/ethnicity, gender, and age subgroups and the national population.

RESULTS: National incidence rates in 2023 were …

Student-Centered Approaches For Improving Teaching Quality In College Animation Courses Under Possibility Neutrosophic Soft Sets, Xiao'ou Ji, Juan Song

Neutrosophic Sets and Systems

No abstract provided.

Animation And Game Design Effectiveness Analysis For Skill Development: An Analytical Framework Using Neutrosophic Hesitant Fuzzy Set, Na Ji, Xiao'ou Ji

Neutrosophic Sets and Systems

No abstract provided.

Crediting Prison Crime, Jacob Gordon

NULR Online

No abstract provided.

Differential Impacts Of Wind And Waves On Albatross Flight Performance In Two Ocean Basins, Ian J. Maywar, Richard A. Phillips, Rachael A. Orben, Melinda G. Conners, Scott A. Shaffer, Lesley H. Thorne

Faculty Research, Scholarly, and Creative Activity

Background: Albatrosses can commute long distances to feed during the breeding season by avoiding energetically costly flapping flight. Energy from both wind and waves can be used to sustain soaring and reduce flapping flight, yet most studies of albatross flight have focused solely on the influence of wind. Methods: To examine how wind and waves allow albatrosses to reduce energetic costs by limiting flapping flight, we analyzed how the flap rates of five albatross species (370 individuals) across two ocean basins varied with wind speed and swell height. Results: For all study species, soaring using both wind and waves resulted …

A Modular Design And Construction Framework For Enhancing The Sustainability Of National Housing Projects In Egypt, Ayman Ahmed Ezzat, Farah Ibrahim El Sahzly

Mansoura Engineering Journal

Egypt’s national housing sector faces mounting sustainability challenges due to outdated design and construction practices that cause material waste, high costs, and inefficient resource use. This study develops a framework for integrating modular design and construction principles into Egypt’s National Housing Projects (NHPs) to strengthen their social, economic, and environmental sustainability. A mixed-method approach combined a literature review, case studies, and a survey of Egyptian Architectural Design Firms (ADFs). The literature review revealed a global consensus on the benefits of modular design and construction, such as improved efficiency, reduced waste, and faster project delivery, yet found limited adoption in Egypt …

Dialogic Engagement In Scientific Discourse: An Appraisal Analysis Of Discussion Sections By Arab L2 And Native English Writers, Mohammed Ahmed Mohammed Alzahrani

UB Journal for Humanities

The discussion section of a research article is a critical site of persuasion, where writers must strategically negotiate claims, credibility, and collegiality. This study investigates how cultural and linguistic backgrounds shape this delicate rhetorical act by conducting a contrastive analysis of dialogic engagement in scientific discussions. Employing Martin and White’s (2005) Appraisal Theory, specifically the Engagement Framework, the researcher analyzed a specialized corpus of 40 research articles in Molecular Biology and Organic Chemistry, written by Arab L2 and Native English (NE) writers. The analysis reveals a stark, statistically significant divergence in the frequency and distribution of these resources: Arab L2 …

An Analysis Of Developmental Changes In Twitch Patterning During Rem Sleep, Claire Wolfer-Jenkins, Taylor Svoboda

The Journal of Purdue Undergraduate Research

No abstract provided.

Straw Cover Increases Garden Soil Microbial Biodiversity, Emory Walker, Mara Welty, Emma Creviston

The Journal of Purdue Undergraduate Research

No abstract provided.

Using Neural Networks To Predict Microstructure Evolution In Granular Materials, Prashant Rajesh Iyer

The Journal of Purdue Undergraduate Research

No abstract provided.

A Qualitative Analysis Of Cyclical Patterns In Bobcat Movement In Relation To Seasonal Flooding And Species Life History, Sierra A. Hunnicutt

The Journal of Purdue Undergraduate Research

No abstract provided.

The Evolution Of Tyrosine Kinase Activity And Chance, Contingency, And Necessity In Evolution, Michael Gardner

The Journal of Purdue Undergraduate Research

No abstract provided.

Computational Analysis Of Calcium Binding Sites In Calmodulin And Their Role In Activating Adenylyl Cyclase 1, Shreya Krishnan

The Journal of Purdue Undergraduate Research

No abstract provided.

Making A Splash: Using Mass Spectrometry To Measure Dopamine And Serotonin Activity In Brains Of Water-Enriched Pekin Ducks, Nina Wilson

The Journal of Purdue Undergraduate Research

No abstract provided.

Validation Of Innovative Method Of Murine Vertebral Compression Testing, Sarah Staller

The Journal of Purdue Undergraduate Research

Murine vertebral compression testing is a common technique to quantify trabecular bone biomechanics. Having a precise method of vertebral compression is important for aiding researchers in making clinically relevant discoveries in musculoskeletal research. While many methods exist in literature, there has yet to be established a universal protocol for this procedure. Many challenges exist in vertebral compression, such as the irregular shape of the vertebral body (trabecular region of interest), uneven endplate surface morphology, and surrounding cortical processes. Therefore, the aim of this study was to develop a new method of vertebral compression that accounts for these factors and to …

Just "Beet" It? A Comparison Of Road Salt Effects On The Life History Of Daphnia Magna, Koby Sellner

The Journal of Purdue Undergraduate Research

In areas that experience snow and ice, deicing reagents such as road salts are often used on roads to promote safer driving conditions. However, road salts run off into local vegetation, soil systems, and (my focus) freshwater systems. The impacts of excess salt and chloride in freshwater have been studied extensively on a broad diversity of organisms under different conditions, but previous studies have rarely used different types of road salts. Zooplankton are primary consumers in many freshwater systems, feeding on phytoplankton and serving as prey for predator species higher in the trophic chain. These animals generally are impacted negatively …

The Automation Of Lamp Biomolecular Assays Using The Eppendorf Epmotion™ 5075 Robotic Pipettor, Shamalaa Sathiasealan

The Journal of Purdue Undergraduate Research

Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique known for its specificity and efficiency in less controlled environments than laboratories. Designing novel LAMP reagents requires strict contamination control, and unlike the more commonly automated polymerase chain reaction, LAMP’s heightened sensitivity poses unique challenges to automation. To address this, we optimized automation procedures for LAMP using a robotic pipettor without altering the core assay itself. This project focuses on minimizing contamination using sealed plates, reducing operator intervention by automating pipetting, and preventing enzyme degradation using cooling plates. Our approach employs pre-slit pierceable seals and cooling blocks to prevent cross-contamination …

Effects Of Alcohol Exposure On Recognition Memory And Marble-Burying Tasks In Male And Female Aged Mice, Roma Kamat, Tori Burke

The Journal of Purdue Undergraduate Research

Alcohol consumption in aging humans is a risk factor for cognitive impairment. This experiment assessed the effects of binge-like alcohol drinking in aged mice on memory (using the object recognition memory [ORM] task) and on anxiety-and compulsive-like behavior (using the marble-burying task). Subjects were 8 female and 10 male mice, 14–15 months old, selectively bred for low alcohol preference (LAP). Mice consumed either tap water or a 20% alcohol (v/v) solution in tap water through a drinking in the dark (DID) procedure for 4 consecutive days per week, for 3 consecutive weeks. One and 11 days after DID, mice completed …

The Due Process And Policy Implications Of The Laken Riley Act, Abigail Adu

University of Cincinnati Law Review

No abstract provided.

Enabling Unpredictability And The Perils Of Judicial Science And Math In Ohio V. Epa, Neil Taylor, Bradford Mank

University of Cincinnati Law Review

No abstract provided.

The Bruderhof's "System Of Objects": A Case Study In Material Culture And Christian Praxis, 1920-2001, David J. Howlett

Communal Societies

No abstract provided.

A Visit To Iptingen, John S. Ruch

Communal Societies

No abstract provided.

Translation, Controversy, And Research Strategy: What Can Be Learned From George Rapp's Response To A Shaker's Inquiry, Walter A. Brumm

Communal Societies

No abstract provided.

Property And The Management Of Culture: The Construction Of Community At Hopedale, 1842-1856, Thomas Stone

Communal Societies

No abstract provided.

A Cave In Miocene Conglomerate: The Törökpince-Abaliget Cave System, Hungary, Krisztina Sebe, Piroska Pazonyi, Márton Bauer, Bálint Szappanos, Márton Szabó, Zoltán Szentesi, Mihály Gasparik, Ákos Juhász, Luca Pandolfi, Máté Gregorits, József Haász, Ágnes Novothny, Zsófia Ruszkiczay-Rüdiger

International Journal of Speleology

Conglomerate caves are rare, and only a few have been described in the scientific literature. Here, we present a newly discovered and significant cave system in SW Hungary, comprising over 500 m of upper passages and a shorter, lower section of a through-cave developed in Lower–Middle Miocene conglomerates. The formation of these cave passages was controlled chiefly by bedding and fractures. Dissolution has produced typical karstification morphologies, whereas corrasion, granular disintegration, and rock collapse have also played a role in shaping the cave. The cave is dominated by vadose-zone morphologies, but sediment infills indicating upward water flow, along with ceiling …

Dark Error's Night Will Soon Be Gone!: Dynamics Of Participation In New Harmony, 1824-1827, Peter Hohn

Communal Societies

No abstract provided.

The Brotherhood Of The New Life, Brocton: Fictionalized Accounts Of Community, Catherine Mcallister

Communal Societies

No abstract provided.

A Prospective Observational Study On Role Of Intraoperative Renal & Muscle Oxygen Saturation On Post-Operative Serum Creatinine Level In Patients Undergoing Cardiac Surgery On Cardiopulmonary Bypass, Bhakti Banerjee, Haripada Das, Lini Srivastava, Snigdha . Pramanik, Diptimay Majumder

Journal of the Saudi Heart Association

Objective Near Infra-Red Spectroscopy (NIRS), can be used to monitor renal tissue oxygenation (SrO2), as well as thenar muscle oxygenation (SmO2). In this study, we have examined the ability of SrO2 and SmO2 in predicting cardiac surgery related change in serum creatinine level (ΔsCr) and explored any correlation between these two parameters.

Methods This study included 55 adult patients (18 to 60 years), who were scheduled for elective cardiac surgery with cardiopulmonary bypass (CPB), having no pre-existing renal impairment, with skin-to-kidney depth ofSmO2, preoperatively. ΔsCr was investigated at 24, 48 and 72 hours post-operatively. Relative thresholds of SrO2 and SmO2 …

Pheonix Imagery In Early Christian Art, Annie Spach

Studia Antiqua

In Early Christianity, often Christians used popular symbols that would point back to greater truths taught in their new faith. This paper discusses how early Christians followed his council through the use of the imperial representation of the phoenix rather than the common representation, highlighting their belief in resurrection, the majesty of Christ and their hope for eternal life given to all believers, while also speaking to a greater tradition outside of Christianity. The continued use of the phoenix as a symbol of resurrection, renewal, immortality and eternal life in the paradise of God is discussed, as well as the …