Digital Commons Network^™

Novel Physical And Biological Applications Of Carbon Ion Radiotherapy, Danushka Seneviratne, Prapannajeet Biswal, Sunil Krishnan

The Brown Foundation: Institute of Molecular Medicine

Carbon ion radiation therapy (CIRT) is a high-LET radiotherapy, which distinguishes itself from traditional low-LET radiation, such as photons and protons, through its unique physical aspects, biological attributes, and the dramatically increased damage it causes within cellular DNA. Given its distinctive characteristics, it is expected to improve the therapeutic ratio of radiation treatments and enhance treatment outcomes in traditionally radiation-resistant tumor histologies. Despite these unique properties, much remains to be understood regarding the clinical use of CIRT before its full potential can be realized. In this review, we summarize the distinct advantages of CIRT with regard to its physical and …

Impact Of Chilling, Freezing, And Repeated Freeze–Thaw Cycles On Physical Quality Of Buffen, Chevon, And Chicken Meat, Tarique Ahmed Khokhar, Atta Hussain Shah, Muneer Ahmed Jamali, Asghar Ali Kamboh, Faiz Muhammad Khand, Muhammad Awais Soomro, Zafar Ali Khoso, Muhammad Mohsen Rahimoon

Journal of Bioresource Management

Chilling, freezing, and repeated freeze–thaw cycles are common meat preservation methods; however, they can alter key physicochemical properties. Comparative data across different species under standardized conditions are limited. To compare the effects of chilled storage, frozen storage, and repeated freeze–thaw cycles on pH, water-holding capacity (WHC), thaw loss, cooking loss, and drip loss in buffen (buffalo), chevon (goat), and chicken meat. Longissimus dorsi muscles from buffalo and goat, and breast meat from broiler chickens, were stored under chilled (2–4 °C), frozen (–10 to –12 °C), or repeated freeze–thaw conditions. "Measurements were performed at defined intervals of chilling, freezing and freeze …

Effect Of Supplementation With Valine, Isoleucine, And Tryptophan Amino Acid On Growth Performance, Carcass Traits, And Nitrogen Excretion, Of Broiler Chickens Fed Low-Protein Diets, Ahmed Abd-Elaziz Abdallah, Mona A. Mahmoud, Mohamed M. Khalifah, Marwa R. El-Deken, Bahaa M. Abou-Shehema, Mohamed E. Farag, Mervat S. E. Yossef

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

This study investigated the effects of supplementing low-protein diets with valine (Val), isoleucine (Ile), and tryptophan (Trp) on growth performance, carcass traits, blood parameters, and nitrogen excretion in broiler chickens. A total of 168 one-day-old unsexed Ross-308 broiler chicks were randomly divided into six groups: a positive control (PC) fed a basal diet, a negative control (NC) fed a low-protein diet supplemented with six essential amino acids, and four groups fed the NC diet with additional Val+Ile (5% or 10%) and Trp (5% or 10%). The results showed that the NC+5% Val+Ile group had significantly higher body weight gain (BWG) …

A Comparison Of Social, Economics, And Communication Factors Between Adopting And Non-Adopting Conservation Agriculture Wheat Farmers In Nineveh Governorate, Iraq, Mahmood Khalaf Wasmi Alkhulaifi, Abid Ali Hasan Al-Doski

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

The research aimed to examine and compare the key socioeconomic and communication factors influencing wheat farmers’ adoption and non-adoption of conservation agriculture (CA) techniques in Nineveh Governorate, Iraq, during the 2023–2024 agricultural season. A total of 450 respondents were selected for the study—225 adopters (representing the entire group of CA adopters) and 225 non-adopters—drawn from a total farming population of 1,061 within the same adoption areas of Nineveh Governorate.

A combination of descriptive and quantitative analyses was employed to process the data, utilizing both t-tests and z-tests. The significance analysis revealed statistically significant correlations between CA adoption and several socioeconomic …

Integrated Vermicompost And Microbial Inoculation Enhance Growth, Yield, And Volatile Oil Composition Of Coriandrum Sativum L., Fatma Ahmed Fouad, Fatima A.A. Al Otaibi, Ahmed Ali Mahmoud

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

An eleven-treatment field trial examined the effects of different rates of vermicompost (vermi.) (100%, 75%, and 50% of the recommended dose) in combination with bio-fertilizers [Azotobacter sp. and arbuscular mycorrhizal fungi (AMF)] on the performance of Coriandrum sativum L. during the winter seasons of 2023-2024 and 2024-2025. The treatments comprised an unfertilized control and all factorial permutations of vermicompost level with Azotobacter and/or AMF inoculation (100% vermicompost, 100 % vermicompost + Azotobacter, 100% vermicompost + AMF, 100% vermicompost + Azotobacter + AMF, 75% vermicompost + Azotobacter, 75% vermicompost + AMF, 75 % vermicompost + Azotobacter + …

Molecular Profiling Of Fungi Using Specific Primers, Faten A. S. Alsulaimany

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Accurate information about fungal identification is very important in various fields, such as medical, agronomic, environmental, and industrial. Traditional morphological and biochemical-based assays can be time-consuming, nonspecific, and fail to detect cryptic or uncultured species. Conversely, molecular profiling based particularly on the use of specific primers in polymerase chain reaction (PCR) methods offers a highly efficient alternative, as it is sensitive, highly specific, and relatively fast. This paper presents general aspects of fungal molecular profiling, the main genetic regions commonly employed: Internal Transcribed Spacer (ITS), Large Subunit (LSU), and Beta-tubulin(β-tubulin), and how to use specific primers for varied …

Spatial Variation Of Heavy Metals Uptake In Ashar Plant (Calotropis Procera) Organs: Implications For Air Pollution Mitigation In Riyadh, Mazen Fawaz Alraddadi, Mohammed Saba, Samir Gamil Al-Solaimani, Mansour Ahmed Alghamdi

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Phytoremediation is an eco-friendly and effective method that uses plants to reduce heavy metal pollution by absorbing and accumulating contaminants from the environment. This research focused on the native Al-Ashar plant and examined its potential as a bioindicator and agent for cleaning heavy metal contamination near a cement factory in Riyadh, Saudi Arabia. Soil and plant samples were gathered from sites at different distances from the factory (5 m, 50 m, 100 m), including a control site, and analyzed for metals such as copper, iron, manganese, chromium, cobalt, lead, and nickel.

The results showed elevated levels of these metals in …

Invasive Candidiasis In Critically Ill Patients: Fundamental Concepts And Future Directions, María Alejandra Pérez, Wesley J Hoffmann, J Christian Pérez, Max W Adelman

Faculty, Staff and Student Publications

Topic importance: Invasive candidiasis (IC) is a common complication in patients in ICUs. IC can be divided into bloodstream infections (candidemia) and deep-seated infections. Candida infections are associated with high mortality and longer hospital stays. Moreover, the emergence of Candida auris and other species prone to cause ICU outbreaks highlights the importance of this pathogen.

Review findings: Candidemia represents about 20% of bloodstream infections in ICU patients, whereas intraabdominal candidiasis, the most common form of deep-seated infection, predominantly affects surgical ICU patients. Regarding species distribution, Candida albicans is the most common species; however, non-albicans species have become more prevalent in …

Dcpr: A Deep Learning Framework For Circadian Phase Reconstruction, Xiao Han, Xiaochen Cen, Zhijin Li, Xiaobo Zhou, Zhiwei Ji

Faculty, Staff and Student Publications

Background: The circadian clock is an evolutionarily conserved system that orchestrates 24-h physiological rhythms through transcriptional and translational feedback loops. Mounting evidence suggests a bidirectional relationship between circadian rhythm alteration and disease progression, positioning the circadian clock as a potential therapeutic target. Due to the scarcity of high-resolution temporal omics data, it remains very challenging to elucidate the underlying regulatory mechanisms of the circadian system. As a practical alternative, public untimed transcriptomic datasets offer the potential to infer gene expression oscillations retrospectively. However, existing computational approaches for circadian phase estimation often suffer from limited predictive accuracy, reducing their ability to …

Towards Computational Methods In Medical Data Analysis: From Speech And Text To Imaging, Kristin Qi

Graduate Doctoral Dissertations

Early detection of cognitive decline and efficient medical image analysis remain critical challenges in healthcare. Traditional clinical assessments are infrequent and resource-intensive, while everyday speech data and unlabeled medical images remain largely unexploited. This dissertation develops computational methods integrating machine learning and artificial intelligence across speech, text, and imaging modalities to address challenges in medical data processing. For cognitive monitoring, this work first introduces methods using voice assistant systems to collect longitudinal speech data in home environments, demonstrating that incorporating historical session patterns significantly enhances detection of mild cognitive impairment. Building on this foundation, a framework combining large language model-driven …

In Silico Target Identification For Antioxidant And Anti-Inflammatory Activity Of Oil Palm Leaves Extract After Biotransformation Process, Galuh Permatasari, Irma Kresnawaty, Annisa Aulia Aksa, Djoko Santoso, Widodo Widodo

Makara Journal of Science

Oil palm leaf extract (OPLE) contains abundant phenolic and flavonoid compounds with recognized antioxidant and anti-inflammatory potential; however, its pharmacological applications remain underexplored. This study aimed to optimize the enrichment process of OPLE and characterize its bioactive compounds using integrated in vitro and in silico approaches. The extraction was optimized by incorporating trichloroacetic acid and extending the incubation time to 48 h, resulting in significantly increased total phenolic content and antioxidant activity compared with the control. LC–MS/MS profiling identified 14 flavonoid compounds with diverse biological functions. Among these, Rhamnetin-3-O-β-D-glucopyranoside, Kaempferol-3-O-rutinoside, and Nelumboroside A exhibited the strongest antioxidant and free radical …

Development Of Shigella Flexneri Detection Method By Real-Time Polymerase Chain Reaction Targeting The Sfmd Gene, Muktiningsih Nurjayadi, Puan Aqila Azizah, Agus Setiawan, Ananda Indah Putri Sihombing, Anisa Fitriyanti, Grace Grace, Gusti Angieta Putri, Helzi Angelina, Royna Rahma Musie, Jefferson Lynford Declan, Gladys Indira Putri, Dandy Akbar Juliansyah, Siti Fatimah, Tiara Fahriza, Irma Ratna Kartika, Fera Kurniadewi, Novitasari Novitasari, Bassam Abomoelak, Hesham Ali El Enshasy, Shyi-Tien Chen

Makara Journal of Science

Shigella flexneri can cause shigellosis, which results in high fever, vomiting, diarrhea, or death. This study developed a detection method based on real-time polymerase chain reaction that targets the sfmD gene of S. flexneri given that the virulence factor encoded by this gene is thought to facilitate adhesion to a host surface. The proposed method involves primer design, DNA isolation, the optimization of primer annealing temperature, and confirmation, specificity, and sensitivity tests. A sfmD primer with an amplicon length of 155 bp was annealed to the target DNA at an optimized temperature of 60 ℃ (range 54 °C–62 °C). This …

Terrestrial Gartersnake (Thamnophis Elegans) Consuming A Western Meadow Vole (Microtus Drummondii) In The Sangre De Cristo Mountains Of New Mexico, Joseph W. Paysen, Peggy M. Huss, Jacob C. Cooper, Lance J. Bernal, Carter Kruse, Keith Geluso

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The Terrestrial Gartersnake (Thamnophis elegans) is a dietary generalist occurring in the western half of the United States, southwestern Canada, and northern Mexico. Terrestrial Gartersnakes are known to consume a variety of small mammals, including voles (Microtus). Herein we report on an observation of the Terrestrial Gartersnake consuming a Western Meadow Vole (Microtus drummondii). On 27 June 2025, we captured a large adult Terrestrial Gartersnake underneath a log just upstream of a North American Beaver (Castor canadensis) dam on the Vermejo River, Colfax County, New Mexico that regurgitated a partially digested adult …

The Evolving Therapeutic Landscape Of Nanoscale Cancer Drug Delivery Systems: Future Perspectives, Nafeesa Qudsia Hanif, Bushra Arshad, Anila Fariq, Syed Imam Hussain Abidi, Sohail Ameer Marwat, Aneela Fatima

Journal of Bioresource Management

Cancer is one of the main causes of deaths in the world. Conventional cancer therapeutic approaches such as chemo- and radiotherapy have burdened the cancer patients with arduous physical and psychological challenges. Moreover, in case of onset of this disease, huge amount is required against the medications (chemotherapy and radiotherapy). It is estimated that annually, the increasing cancer disease incidence rate is alarming. In developed countries, the health support is given by the nation. Therefore, the health managements in the developed nations are over-burdened due to heavy expanses against expansive cancer therapy treatments. Interestingly, tumor treatments have undergone a comprehensive …

Biofunctional Characterization Of A Polyherbal Formulation, Muhammad Ameer Qarib Naqvi, Iqra Saleem, Fatma Hussain

Journal of Bioresource Management

Polyherbal formulations (PHFs) have greater medicinal importance due to their enhanced bioactivities. To check whether a combination of several plants enhances bioactivities, the current study was designed. Methanol, aqueous and n-hexane solvents were used to prepare PHF of Syzgium cumini, Origanum vulgare, Aloe vera barbadensis Miller and Gymnema sylvestre. DPPH (2, 2-diphenyl-1-picrylhydrazyl scavenging) assay was used to analyze antioxidant activity. The total phenolic content (TPC) and total flavonoid content (TFC) estimations were done by Folin-Ciocalteu reagent and AlCl₃ colourimetric techniques, respectively. Bactericidal activity was measured by agar well diffusion method, anti-diabetic profile was assessed by …

Economic Analysis And Technical Efficiency Of Cassava Production In Rural Households Of Yewa South Local Government Ogun State, Babatunde Taiye Oluwasola, Babatunde Oluyemisi Omowunmi, Andokeke Nkemdiri Nobert

Journal of Bioresource Management

The study examined economic analysis and technical efficiency of cassava production in rural household in Yewa South local Government area of Ogun state. Structure questionnaires were administered to one hundred registered cassava farmers within the ten (10) villages. Descriptive and inferential statistics was used to analyze the data; results revealed that the age of the cassava farmers ranged between (25 – 45) years. Only 55.0 % of the farmers were married, having both primary and secondary education respectively, majority (63.0 %) having 11-15 years of experience. The result of the frontier on the efficiency of cassava production of farmers showed …

Archaeology Of Roads: A Case Study Of The 18th-Century Surosowan–Tasikardi Old Road In Banten Lama As The Sultan’S Road, Destian Pandu Dwicahyo Santoso Putro, Ghilman Assilmi

Paradigma: Jurnal Kajian Budaya

Archaeological studies on roads in Indonesia remain relatively limited, although international research indicates that roads are not merely transportation infrastructure, but also embody social, political, and symbolic dimensions. A significant example is the ancient road in Banten Lama, which connects the Surosowan Palace with the artificial lake of Tasikardi. This study aims to present archaeological data and identify the distinctive characteristics of royal roads compared to common roads, applying a landscape archaeology approach within a post-processual paradigm. The research stages include data collection, processing, and interpretation through qualitative methods, encompassing literature review and field observation. The analysis shows that the …

Ending Gender-Based Sexual Violence On Canadian Campuses: Peer Educator Perspectives, Jason A. Laker

Faculty Research, Scholarly, and Creative Activity

Gender-based and sexual violence (GBSV) remains a pervasive problem in higher education, disproportionately affecting marginalized students and undermining their safety, well-being, and academic success. Post-secondary institutions (PSIs) increasingly rely on peer educators (PeerEds) to deliver prevention and response programs, leveraging their shared student experience to foster trust and engagement. This study explores the motivations and experiences of GBSV PeerEds in Canada and the United States, revealing how personal trauma, institutional critique, and allyship drive their involvement. Findings highlight the emotional labour, secondary trauma, and systemic constraints PeerEds face, alongside their contributions to campus culture and advocacy. The study critiques institutional …

Adaptive Energy-Aware Communication For Healthcare Iot Systems: A Simulation-Based Approach, Huthaifa Ayad Al-Ani

Al-Farahidi Expert Systems Journal

Healthcare Internet of Things (HIoT) systems play a pivotal role in continuous patient monitoring, yet they face persistent challenges related to limited energy capacity and strict latency requirements. This study proposes an adaptive, energy-aware communication strategy for HIoT devices that minimizes energy consumption while ensuring rapid data delivery during critical health events. Using the publicly available UCI Smart Heart Monitoring System dataset (2,200 real patient records), a Python 3.11-based simulation framework was developed utilizing NumPy, Pandas, and Matplotlib libraries. The proposed adaptive transmission model dynamically adjusts data transmission frequency in response to real-time physiological states and is directly compared with …

The Efficacy Of Essential Oils In Promoting Youthful Skin: A Review, Diaa El Din Ashraf Hemdan, Riham A. El-Shiekh

Bulletin of Faculty of Pharmacy Cairo University

Background Skincare essential oils [EOs] are gaining recognition for their effectiveness as natural solutions to promote youthful skin. These concentrated plant extracts provide a variety of benefits, including hydration, antioxidant protection, and anti-inflammatory properties. Purpose This review highlights the potential of the most common used EOs for healthy skin. Methods The search was conducted using all available MeSH terms for anti-aging & EOs. Results Notable oils such as lavender, rose, and geranium are celebrated for their moisturizing and rejuvenating effects, making them popular choices in anti-aging skincare formulations. In addition to their hydrating properties, EOs like lemon and frankincense play …

Investigations On The Pharmacognostic Characteristics Of Capparis Species I-Lectins, Hussein Ali Hussein Al-Sa'idy, Abbas Khazaal Okab, Hussein K. Alkufi, Hayder Naji Sameer

Maaen Journal for Medical Sciences

Background: As glycoproteins widely distributed in the plants of carbohydrate binding specificity, lectins are considered macromolecules of paramount significance. Their sugar based binding dependent agglutination property nominates them for blood grouping as well as GIT complications management.

Objective: Exploring the nature, classifications, and pharmacological properties of lectins, particularly those found in Capparis species and their aqueous extracts within the last 20-25 years is the aim of this review.

Methods: This review evaluates pharmacological studies of Capparis lectins, emphasizing therapeutic effects identified through focused keyword searches.

Results: Capparis lectins and aqueous extracts exhibit diverse biological activities, including anti-rheumatic, hypoglycemic, immunomodulatory, and …

Installation Characteristics In Historical Sites, Marwa Metwally

Journal of Art, Design and Music

One of the most popular artistic movements of the modern period is installation art. Numerous inspirations have been crucial in defining it and emphasizing its many facets, representing varied viewpoints and feelings pertaining to the recipient on the one hand and the artist on the other. How the artwork is interpreted artistically is also greatly influenced by its aspects and components. many historical sites represent integrated artworks that incorporate the various characteristics that constitute the art of installation art. On the one hand, they blend many forms of architecture and art, and on the other, they produce a significant cultural, …

The Impact Of Egyptian Cultural Cartoons On The Child’S Culture, Sandra Ashraf Gamal Fahmy, Nagwa Yehia El Adawy, Niveen Ezzat Gamaleldien

Journal of Art, Design and Music

The field of animation has been used for years by animation companies to create cartoons, animated movies and character that is loved by adults and children and participates in teaching the viewer life lessons. The objective of the research is to illustrate the importance of creating Egyptian cartoons to educate the children about their own country, culture, beliefs and values and to decrease the impact of foreign cartoons. The research also discusses examples of well-known Egyptian cartoons and the impact they had on children. In addition to that, the research explains how the lack of Egyptian cartoons leads children to …

Digital Technology: A New Frontier For Sculpture In Urban Spaces, Muhammad Muhammad Ali Shaheen, Marwan Abdullah Hussein, Dina Radwan Mohamed Radwan

Journal of Art, Design and Music

Digital technology has transformed the field of sculpture by expanding creative possibilities and redefining the relationship between form, space, and audience. This research explores how contemporary sculptors employ digital tools—such as virtual modeling, 3D design, and digital media—to create innovative works in open urban spaces. These technologies have enabled the development of kinetic and interactive sculptures that respond to environmental stimuli or viewer interaction, enhancing public engagement and allowing for more complex, large-scale, and conceptually rich works. . The research is based on a descriptive analytical approach, which examines the intersection of the creative talent of the sculptor designer with …

Influence Of Family Health History And Parental Education On Body Mass Index, Blood Pressure, And Lipid Levels In 5th Grade Children: A Secondary Data Analysis Of The Cardiac Project, Madha Rani Das, Lee A. Plyes, Eloise Elliott, Christa L. Lilly

Journal of Appalachian Health

Introduction: Childhood obesity and related cardiovascular risks reflect the interplay of genetic predispositions and socioeconomic adversity. Appalachia’s poverty, limited health care, and educational gaps worsen family health risks, driving early cardio-metabolic problems in children, highlighting the need for effective interventions.

Purpose: The purpose of this study is to examine the association of family health history and parental education with BMI, BP, and lipid profiles among 5^th grade children in West Virginia (WV).

Methods: The study used WV CARDIAC data from 2006–2009. Outcomes were BMI, SBP/DBP, and fasting lipids (HDL, LDL, TG). Predictors were parental education and family health history …

Umwelt, Sujetos Transindividuales E Intencionalidad Compartida: Cuerpo, Significación Y Socialidad En La Construcción Del Conocimiento, Juan C. González Vidal

Journal of Roleplaying Studies and STEAM

En este trabajo abordamos, desde el punto de vista semiótico, el vínculo indisoluble que existe entre el cuerpo humano, la significación y la socialidad. Partimos del postulado de que el cuerpo es, desde el nacimiento, una entidad sintiente; luego, una vez adquirida la capacidad de generar procesos semiósicos primarios, empieza a ordenar y a clasificar los estímulos exteriores, hecho en el que se asienta el fundamento de su orientación básica en el entorno. Conforme aumentan sus competencias semiósicas, se incrementan sus capacidades perceptivas y cognitivas que, al ser afirmadas, lo llevan a alcanzar finalmente los más altos grados de socialidad. …

From The Pages To The Gaming Table: Designing A Homebrew System To Adapt A Book Series Into A Ttrpg, Ricardo Victoria Uribe, Nazario Robles Bastida, Chris Birmingham

Journal of Roleplaying Studies and STEAM

Adapting media properties, in particular fantasy, science fiction, and horror books, has been a staple of the development of tabletop role-playing games since their inception. Different properties, ranging from Lord of the Rings to Call of Cthulhu and everything in between has been undergoing this process. Developing an indie game based on indie and self-published books can be used as a promoting tool on overlapping audiences, which is the case for the selected book series for this design exercise. This paper has the aim of sharing these developing experiences during the early stages of creating a quick start guide supplement …

Journal Of Roleplaying Studies And Steam (Jrpssteam) Vol. 4 [2025], Número 2 (Issue 2), Cristo Leon, Romano Ponce-Díaz Phd, Ivan Avila Gonzalez Phd, James Lipuma Dr., Bruce G. Bukiet, Ricardo Victoria-Uribe, Nazario Robles-Bastida, Chris Birmingham, Ximena Diaz Santillan, Edgar Francisco Vázquez Martínez He, Jorge Prieto Terrones, Juan Carlos C. González Vidal S, Edgar Meritano, Laura Magela Garcés Ramírez

Journal of Roleplaying Studies and STEAM

En una sesión de juego por medio del registro lingüístico se organiza la escena, se orienta la manera de nombrar las tareas, se distribuyen los roles actanciales, se establecen la expectativas; por lo tanto, se establece una puesta en escena. De tal forma, las prácticas lúdicas y ficcionales se configuran a partir de nuestra mirada del mundo e irremediablemente también reconfiguran esa misma mirada. El ser y el estar en un espacio es la especificidad mediática fundamental de los juegos de rol; dicho de otra manera, en los sistemas de juego de rol dentro de sus universos narrativos, en su …

Traversing The Internal And External Worlds: An Analysis Of Du Fu’S Use Of Nature Imagery, Arwen Mox

Rushton Journal of Undergraduate Humanities Research

Born in 712, the Chinese poet Du Fu lived in the cultural peak of the High Tang and the devastating events and aftermath of the An Lushan Rebellion in 755. This essay explores how Du Fu employs nature imagery as a medium for reflection the internal and external worlds. By tracking the use of this motif across the three major periods of his work as embodied in three different poems, the nuanced shifts in his portrayal of nature and humanity becomes apparent. This essay argues that nature is a versatile medium within Du Fu’s work.

Under The Influence: New York’S Crisis Of Addiction, Exploitation, And Drug Policy Within Depression-Era Films, Simone White

Rushton Journal of Undergraduate Humanities Research

During the 1930s, New York City stood at the center of media innovation and cultural influence. It was also the center of the continuing opioid epidemic and a pivotal site for the reception and promotion of addiction films. This article argues that Depression-era films, The Struggle (1931), Narcotic (1933), and Assassin of Youth (1938), reflected economic, political, and moral anxieties surrounding drug abuse. Using National Board of Review records, studio pressbooks, and contemporary periodicals, this study examines how cinematic portrayals of addiction influenced ideologies, criminalized users, and deepened social stigma.