Digital Commons Network^™

Inward Versus Outward Foreign Direct Investment And Economic Growth: A Case Study Of China, Xiaoning Chen

Plymouth Business School Theses

The thesis aims to investigate the determinants of IFD and OFDI and their impact on economic growth. To bridge the research gap, this study uses China as a case study and structures three empirical chapters to investigate the relationship between IFDI, OFDI and economic growth.The structure of the study consists of six chapters, the first empirical study uses time series data and applies the Autoregressive Distributed Lag (ARDL) techniques to investigate the determinants of IFDI from 1980 to 2023, aiming to investigate the determinants of China’s IFDI. The findings demonstrate market openness, human capital, inflation and market size are the …

Prediction Of Phytocompounds For Environmental Sustainability: A Framework Using Computational Tools, Ankita Halder, Sayoni Dam, Sisir Nandi, Asmita Samadder

Trends in advanced sciences and technology

In response to the abruptly elevated environmental impact caused by the usage of chemical-based synthetic compounds in agricultural fields and pharmaceutical pollution, phytocompound-based products have become the choice of use for their ability to foster environmental sustainability. The potential of new phyto-based compounds has been explored in agriculture, phytoremediation, etc. Computer-based in silico prediction through ADMETlab 2.0, SwissADME, and Way2Drug software secured an important role in screening of these phyto-based compounds in terms of lethal concentration (LC₅₀FM, LC₅₀DM), Bioconcentration Factors, IGC50, and role in the TOX21 pathway ahead of their environmental exposure. These aforementioned softwares also …

Empirical Modeling For Prediction Green-Nanofluids Stability Using Minitab Software Towards In Using As Sustainable Coolants, Basma Abdelmoniem, Azza Barakat, Nariman E. Elbaly, Abdelhay.M Abdelhay, Mohamed O. Helmy

Trends in advanced sciences and technology

This research study uses empirical modeling to predict the stability of nano-green fluids, which are designed with a full factorial experimentation design. All experiments were designed, and the analysis was performed by Minitab software. The stability of Al₂O₃/CNT-castor oil was measured by zeta potential, and Al₂O₃/ CNT-jojoba oil was measured by visual sedimentation over days. The dependent variables in each design are magnetic stirring and sonication bath times with three levels for each oil type. The resulting empirical models proved highly effective, with R-squared values exceeding 95% for all formulations. Specifically, the models for castor oil stability reached R-squared values …

Integrated Seismic And Sequence Stratigraphic Analysis Of The Abu Madi Formation, Baltim Field, Nile Delta, Egypt, Nouran Mostafa Eissa, Mostafa Toni, Alhussein Adham Basheer, Amr Talaat, Amir Ismail

Trends in advanced sciences and technology

Despite the economic significance of the Messinian Abu Madi Formation as a primary gas reservoir target in the Nile Delta Basin, a high-resolution, field-scale integration of seismic sequence stratigraphy with quantitative petrophysical characterization remains lacking for the Baltim area. This study addresses this gap by presenting an integrated seismic sequence stratigraphic and petrophysical analysis of the Upper Miocene Abu Madi Formation within the prolific Baltim gas fields, offshore Nile Delta, Egypt. The objectives are to characterize its depositional architecture, delineate reservoir distribution, and assess hydrocarbon potential. The workflow synthesizes well log data from five key wells with a grid of …

Joyful Literature As Life-Giving Pedagogy In Teacher Education, Katherine Egan Cunningham

Education Faculty Publications

No abstract provided.

The Importance Of Hippotherapy: Improving The Lives Of The Disabled Through Alternative Therapy, Jennifer N. Stapleton

UROP Posters

For centuries, horses have been suggested as “healers” and “helpers,” although it wasn’t until the 1900s that horseback riding was scientifically proven as a treatment and rehabilitation method. The exploitation of hippotherapy, the implementation of the three-dimensional pelvic movement stimulated by the oscillation and gait of the horse to combat symptoms of diseases and disorders, has since become a flourishing field of study, but one that is often overlooked. Benefits of hippotherapy often include increased motor neuron function, facilitating proper anatomical alignment, and reducing spasticity. This research analyzes the diverse and dynamic nature of treatment that hippotherapy facilitates, exploring the …

Determining Genes Involved In Recovery From Chemotherapy In 4t1, Emt6, And Eo771 Breast Cancer Cells, Akash Jagdeesh, Joseph Landry Ph.D.

UROP Posters

Breast cancer is one of the most common types of cancer, and often has poor prognosis. Traditional treatments for breast cancer include chemotherapy, which involves a chemical attack on all growing cells within the body. However, these treatments are not 100% effective, and patients might experience recurrence in their cancer months or years after achieving remission. Cancer cells can evade chemotherapy through five mechanisms: senescence, quiescence, cytoprotective autophagy, and apoptosis/necroptosis suppression. Prior studies have conducted CRISPR screens and experiments involving inhibition of epigenetic regulators, to alter the regulation of genes that can contribute to breast cancer chemotherapy resistance. This study …

Establishment Of A Conditionally Replicating Guinea Pig Cytomegalovirus Model For Molecular Characterization Of Latency, Akshay R. Molakalapalli, Saketh Majeti, Michael A. Mcvoy, Jian Ben Wang

UROP Posters

Human cytomegalovirus (HCMV) is a member of the Herpesviridae that establishes life-long latent infections that pose risks of life-threatening disease upon reactivation in immunocompromised individuals. Understanding the molecular mechanisms that govern the latent state is critical for developing effective treatments. However, molecular characterization has been impeded by the scarcity of latently infected cells in vivo and the inability of current in vitro models to support the expansion of clonal latent cell lines. To address these limitations, we developed a novel cell culture model utilizing a conditionally replicating guinea pig cytomegalovirus, a relative of HCMV that mimics HCMV pathology and provides …

Sox11 Overexpression Restores Embryonic Pro-Growth Transcription In Mature Corticospinal Tract Neurons, Eliazbeth Batsel, Zimei Wang, Elizabeth Otten, Syed Roshan, Rabia Mohammad, Paula Pascual, Darby O'Shea, Jose Rosas, Pantelis Tsoulfas, Murray G. Blackmore

Biomedical Sciences Faculty Research and Publications

Neurons in the central nervous system (CNS) display a high capacity for axon growth during early development but lose this ability at a pivotal differentiation stage marked by synaptic maturation, circuit integration, and a profound shift in gene transcription. Once mature, most CNS neurons fail to reverse this transcriptional switch after axon injury, fundamentally constraining their intrinsic capacity for axon regeneration. Here, we show with single-nucleus RNA sequencing that forced expression of the transcription factor Sox11 in mature corticospinal tract (CST) neurons produces large-scale and stable changes in gene expression that are highly enriched for growth-relevant processes, and which strongly …

Clickwrap Accountability, Alicia Solow-Niederman

GW Law Faculty Publications & Other Works

Picture a public-facing generative AI chatbot on a government website that can answer questions about benefits eligibility.  Systems like these expose a sociotechnical-legal divide: they route around the standard due process framework, because there has been no formal government determination, yet they induce reliance from users, above and beyond past rounds of automated legal guidance.  Moreover, if there is an error, current doctrine on government errors and equitable estoppel makes relief unlikely.

This Essay focuses on government deployment of public-facing generative AI chatbots and critically assesses the front-end power dynamics that determine who is filtered out of government programs before …

Creative Destruction For The Patent System? Impact Of Generative Ai, Henry H. Perritt Jr.

Minnesota Journal of Law, Science & Technology

AI raises the provocative possibility that patents could one day become obsolete. AI has the ability both to generate inventions and to simulate the perspective of a person having ordinary skill in the art (PHOSITA). This article explores the transformative impact of generative artificial intelligence (AI) on the United States patent system. The article supports a scenario in which everything becomes invented—and simultaneously, everything becomes obvious—thus challenging a foundational criterion for patentability. These developments can occur within established principles of inventorship, obviousness, and subject matter eligibility under U.S. patent law. Using a narrative case study and a test invention, the …

The Right To Share: Affording Americans Meaningful Control Over Their Data, Kevin Frazier

Minnesota Journal of Law, Science & Technology

Americans today face unprecedented opportunities to leverage their personal data for health, education, and economic benefit; yet state and federal privacy laws increasingly restrict their ability to do so. This Article argues that the prevailing regulatory paradigm—rooted in paternalism, behavioral assumptions, and a deep distrust of both firms and individuals— has produced a system that paradoxically denies people meaningful control over their own information. As artificial intelligence tools grow more capable, the inability of individuals to share data freely threatens to entrench inequities, concentrate access to high-quality AI systems among the wealthy, and accelerate the formation of an “AI abyss” …

Using Drawings To Understand Undergraduates’ Perceptions Of Politics—The Us And Ireland, John Hogan, Sharon Feeney, Paul Kosempel

Research Outputs: 2025-Present

Purpose: This article seeks to gain insights from the interpretations of freehand drawings produced by American and Irish students, young voters, in response to the question: “What is American/Irish politics?” Our goal in using freehand drawing is to foster a collaborative and critical learning environment where participants enhance their ability to interpret and engage in self-reflection. Design/methodology/approach: Freehand drawing is a visual representation method that can bypass cognitive verbal processing pathways as part of a critical pedagogy. This approach enables participants to create clear, more critical, and inclusive depictions of their understanding of a topic, regardless of their vocabulary. Over …

Advancing Greenhouse Air Filtration: Biodegradable Nanofiber Filters With Sustained Antimicrobial Performance, Amirali Bajgholi, Reza Jafari, Alireza Saidi

Études primaires

Air quality management in greenhouses is critical to safeguarding plant health and occupational safety, yet conventional filtration methods often fall short in performance and sustainability. These enclosed environments are prone to the accumulation of bioaerosols, including fungi, bacteria, pollen, and dust particles, which can compromise crop productivity and pose health risks to workers. This review explores recent advancements in air filtration technologies for controlled environments such as greenhouses, where airborne particulate matter, bioaerosols, and volatile organic compounds (VOCs) present ongoing challenges. Special focus is given to the development of filtration media based on electrospun nanofibers, which offer high surface area, …

Occupational Exposure To Pesticides Increases The Risk Of Amyotrophyc Lateral Sclerosis: A Systematic Review And Meta-Analysis, France Labrèche, Pamela Prudhomme, Maryse Gagnon, Nicolas Dupré, Sabrina Gravel

Études primaires

Objective To systematically review the evidence on the association between occupational exposure to pesticides and the risk of amyotrophic lateral sclerosis (ALS).

Methods A systematic search, conducted in eight bibliographic databases for publications between 1990 and 2025, identified observational studies estimating the risk of ALS after occupational pesticide exposure. Study quality was assessed using the WHO Risk of Bias (RoB) assessment instrument for systematic reviews, with the ROBINS-E (RoB in non-randomised studies of exposure) tool domains of bias. Pooled risk estimates were produced using random-effects models with restricted maximum likelihood, heterogeneity was assessed with I² statistics, and meta-regressions and publication …

Parental Beliefs And Behaviors Surrounding Childhood Vaccination, Kamara Braylock, Caitlin Davis, Avery Huff, Alex Springer

MSN Research Projects

Parental hesitancy toward childhood vaccinations continues to present challenges for healthcare providers, public health agencies, and communities striving to protect children from preventable diseases. This project explored the factors that influence parents' decisions about vaccinating their children, using Rosenstock's Health Belief Model (HBM) as the guiding theoretical framework. A review of the literature indicated that vaccine hesitancy rarely stems from a single cause; rather, it reflects a combination of concerns, including fear of side effects, mistrust in the healthcare system, inconsistent information, cultural influences, and varying levels of confidence in medical recommendations. A quantitative, cross-sectional survey design was used to …

Being &Becoming, Valeentina Rodrigues Da Rocha

Grado en Diseño de Moda

Actualmente, vivimos la moda desde ciclos productivos acelerados e industrializados, siendo cada vez más difícil volver a lo imperecedero. Las casas de moda, que antes actuaban con ritmos calmados, se encuentran operando bajo un calendario acelerado, presentando de 4 a 6 colecciones anuales. Contribuyendo a la pérdida de valor del tiempo, el saber hacer y la creatividad. En sus colecciones comerciales cada vez vemos menos atención en la construcción de las prendas, y a más aún en sus materiales y acabados. Este proyecto tiene como objetivo analizar y reinterpretar las técnicas constructivas de la Alta Costura. Se pretende aprender y …

Lgbtq People's Experiences With Crime, Victimization, And The Criminal Legal System, Vanessa R. Panfil

Sociology & Criminal Justice Faculty Publications

The ebb and flow of social control efforts aimed at LGBTQ people necessitate a thorough investigation into their experiences. This review of the literature is organized around four key themes that characterize LGBTQ people's experiences with crime, criminalization, victimization, and the criminal legal system—including police, courts, and carceral facilities. LGBTQ people experience excessive rates of arrest and incarceration and have higher rates of victimization, which illustrate disproportionality. Their experiences differ from those of their cisgender and heterosexual counterparts and are conditioned by age, race, class, gender, and sexual orientation, illustrating intersectionality. The two primary, interrelated mechanisms driving LGBTQ criminalization and …

Revisiting The Rural Folk Devil: Rural 'Othering' And The Connections Between Media Stereotypes And Rural Issues, Brooke Baker, Ida L. Oesteraas, Stephen T. Young, Elizabeth Monk-Turner

Sociology & Criminal Justice Faculty Publications

The current study is a discourse analysis investigating anti-idyllic cinematic representations, specifically in the horror genre, of rural people, places, and cultures. Findings reveal that anti-idyllic images and discourses are prominent within recently released horror films, which rely heavily on framing rural people as the deviant “other.” Special attention is given to the cultural work of these stereotypical depictions and the associated social harms for rural communities. Specifically, we argue that (1) corporations, particularly film companies, contribute to social harm in rural areas by disseminating negative and anti-idyllic representations; (2) these portrayals have tangible and detrimental effects on both people …

Seasonal Wastewater Monitoring And Quantitative Microbial Risk Assessment Of Escherichia Coli In A University Wastewater System, Pathum Thani, Central Thailand, Natsima Tokhun, Natagarn Tongphanpharn, Weerawat Ounsaneha, Montip Jankeaw, Wiriyabhorn Klomsungcharoen, Patsara Wongsudi, Yawanart Ngamnon, Cheerawit Rattanapan, Kwang Mo Yang

Applied Environmental Research

In this study, the physicochemical properties of wastewater were characterized, and a quantitative microbial risk assessment (QMRA) of E. coli was conducted in the wastewater treatment system of the Faculty of Science and Technology, Valaya Alongkorn Rajabhat University, under the Royal Patronage, Pathum Thani, Thailand (VRU-SciTech). This study was conducted because the current water-quality assessment does not include the QMRA or evaluate the occupa-tional and incidental public risk of infection. Over a one-year monitoring period, this study quantified wastewater generation (~6.09 L person-1 day-1; ~3.21 × 103 m3 year-1) and analyzed its physicochemical parameters and E. coli concentrations. High concentrations …

Evaluation Of Soil Moisture Content, Ph, And Dominant Microorganisms In Crude Oil–Contaminated Soil Treated With Cow Dung, Indole-3-Acetic Acid (Iaa), And Simulated Microgravity, Amenze Ovenseri, Tawari-Fufeyin P.

Applied Environmental Research

Crude oil negatively affects soil physicochemical properties and microbial activity, thereby hindering plant growth and posing notable environmental and agricultural issues. The combined effects of cow dung, indole-3-acetic acid (IAA), and simulated microgravity on the recovery of soil degraded by crude oil were explored using Zea mays as the test plant. Soil was contaminated with crude oil at different concentrations (0%, 1%, 3%, and 5% v/w), with each concentration comprising eight treatments: cow dung, Zea mays seeds exposed to microgravity, and IAA alone or in combination. Changes in plant height, soil pH, soil moisture content, and soil microbial diversity were …

Channel-Opening Kinetics Of Complex Kainate Receptors, Noah S. Saunders

Electronic Theses & Dissertations (2024 - present)

Ionotropic glutamate receptors (iGluRs) are found both pre- and postsynaptically in neuronal membranes, and mediate the majority of fast excitatory synaptic transmission in response to the binding of glutamate, a major excitatory neurotransmitter in the central nervous system (CNS). Ionotropic glutamate receptors are divided into three distinct subtypes: kainate, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), and N-methyl-D-aspartic acid (NMDA) receptors. Auxiliary proteins specific to each receptor subtype also play a role in tuning both receptor expression and gating properties, such as neuropilin and tolloid-like (NETO) proteins that modulate kainate receptors, and transmembrane AMPA receptor regulatory proteins (TARPs) that regulate AMPA receptors. Like …

Meaningful Work: A Phenomenological Study Of Embedded Writing Peer Mentors, Susan S. Detwiler

Electronic Theses & Dissertations (2024 - present)

This phenomenological case study examines the experiences of writing peer mentors who are embedded in a first-year inquiry-based writing seminar. It aims to understand how peer mentors who are engaged in the complex practice of supporting first-year writers in a writing classroom make sense of themselves and writing. At a large R-1 diverse university, I interviewed 6 writing peer mentors 3 times over 1 calendar year. I traced their development from mentees, (first-year writing students), through their three semesters of peer mentoring. They also shared written reflections from their training praxis course (a course for peer mentors focusing on their …

Concentration Or Coincidence? Rethinking Random Effects In Spatial And Spatiotemporal Concentration Of Burglary Through A Target-Based Approach, Yichao Gao

Electronic Theses & Dissertations (2024 - present)

Studies of crime and place have long asked how much random processes contribute to the spatial and spatiotemporal concentration of crime. Traditionally, simulations assume that crime incidents occur randomly across microgeographic units—such as block groups, street segments, and parcels—by selecting geographic units at random with replacement. This dissertation takes a different approach, modeling crime incidents as random selections among potential targets, also with replacement. In this framework focusing primarily on burglary, simulated patterns reflect the spatial distribution of potential targets (i.e., properties). This dissertation relies on burglary data from San Antonio, Texas (2017–2019), and measures available burglary targets as individual …

The Communicative Constitution Of Resilience In Graduate-Student Parenthood: Ventriloqual Analysis, Intersectionality, And Sociomaterial Assemblages, Lin Lin

Electronic Theses & Dissertations (2024 - present)

Graduate education is often organized around norms of uninterrupted productivity, flexibility, and professional availability, making graduate study especially challenging for students who are simultaneously raising children. Although prior research has documented the structural barriers faced by graduate student parents (GSPs), less attention has been paid to how resilience is communicatively enacted within the intersection of academic work and family life. This dissertation examines how GSPs communicatively constitute resilience while navigating work-life disruptions. Drawing on Communication Theory of Resilience (CTR) and the communicative constitution of organizations (CCO) perspective, particularly ventriloqual analysis, this study explores how resilience emerges through interactions among human …

Combating Antibiotic Resistance With Plasmid-Dependent Phages, Rhiannon T. Mariano

Electronic Theses & Dissertations (2024 - present)

The alarming rise of carbapenem-resistant bacteria poses an urgent global health threat, driven in large part by the horizontal spread of carbapenemase-encoding plasmids (Ma et al., 2023). These plasmids are often highly mobile and transmissible, enabling rapid dissemination of resistance genes across diverse bacterial populations. Their mobility is largely mediated by conjugation, a process dependent on the formation of pili, which serve as physical bridges for plasmid transfer between cells (Murray et al. 2022; San Millan and MacLean 2017; Virolle et al. 2020). Beyond their role in gene exchange, these pili also act as entry points for a unique class …

When Helpfulness Becomes Harmful: Jailbreaking Llms For Malicious Code Generation, Noelle Capodieci

Electronic Theses & Dissertations (2024 - present)

Generative AI (GenAI) and Large Language Models (LLMs) have made large strides in coding task capabilities, with many software developers integrating agentic engineering into their workflow. While GenAI has largely benefited professional software engineers who can automate their work, it has also created room for those with little coding expertise to also create fully fledged programs and applications. It is commonly noted that GenAI is trained with two major goals in mind: to be as helpful as possible, and be as harmless as possible. There exist moments where helpfulness may be prioritized over harmlessness when these goals conflict. LLMs may …

Fluorescent Protein Imaging Approaches Uncover Dynamic Subcellular Distribution Of Core Clock Proteins In Neurospora Crassa, Ziyan Wang

Dartmouth College Ph.D Dissertations

Circadian clocks are endogenous self-sustained timekeeping systems that allow organisms to anticipate and adapt to daily environmental cycles. Found in diverse forms of life, these molecular clocks regulate the expression of ~ 40% of the genome in animals, fungi, and plants. In animals and fungi, circadian oscillators are built on transcription-translation feedback loops (TTFLs), in which positive regulators drive the expression of negative regulators which, once synthesized and imported into the nucleus, inhibit their own activators. This precisely regulated negative feedback incorporates multiple steps of delays that are essential for generating ~24-hour rhythms. Through these mechanisms, circadian clocks temporally coordinate …

The Serotonin 1b Receptor In Psilocybin’S Therapeutic-Like Mechanisms: From Behavior To Network Reorganization, Sixtine Fleury

Dartmouth College Ph.D Dissertations

Mood disorders represent a substantial and growing global health crisis, with ~10 million adults in the US meeting criteria for a major depressive disorder (MDD). Current first-line treatments such as SSRIs require long-term daily administration and fail a significant proportion of patients, driving renewed interest in rapid-acting alternatives. Psilocybin, a serotonergic psychedelic, shows growing clinical evidence of efficacy in treating depressive and anxiety disorders, often producing therapeutic effects persisting weeks to months following a single dose. Yet, the neural mechanisms underlying these enduring effects remain poorly understood and have been largely attributed to the serotonin 2A receptor (5-HT2AR) based on …

Governing Agroecological Transitions: Landscape Legacies, Participation, And Socioecological Change In The Northeastern United States, Kristen Jovanelly

Dartmouth College Ph.D Dissertations

Agroecological transitions are often presented as purposeful shifts toward more resilient, equitable, and ecologically sustainable landscapes. In practice, these transitions unfold through histories, ecological feedback, institutional arrangements, and contested forms of participation. This dissertation examines how these forces shape what agroecological transitions become, for whom, and with what socioecological consequences across urban and working landscapes in the northeastern United States.

Drawing on historical and critical analysis, ecological modeling, greenhouse experimentation, ethnographic fieldwork, and institutional analysis, I trace transition through urban forests, community-garden seed banks and soils, temperate agroforestry systems, and a participatory tree nursery. Analyses of urban greening and agroforestry …